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Results for rcor1

Z-value: 0.95

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Transcription factors associated with rcor1

Gene Symbol Gene ID Gene Info
rcor1
ENSDARG00000031434 REST corepressor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rcor1dr10_dc_chr17_-_29253918_29253959-0.811.7e-04Click!

Activity profile of rcor1 motif

Sorted Z-values of rcor1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of rcor1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr25_+_182037 3.48 ENSDART00000156469
RPS17
ribosomal protein S17
chr15_-_33816 3.43 ENSDART00000170044
apoa1b
apolipoprotein A-Ib
chr12_-_4351924 2.85 ENSDART00000152168
si:ch211-173d10.1
si:ch211-173d10.1
chr3_-_6078015 2.45 ENSDART00000165715
BX284638.1
ENSDARG00000098850
chr3_-_32686790 2.24 ENSDART00000075465
mylpfa
myosin light chain, phosphorylatable, fast skeletal muscle a
chr3_+_59560881 1.90 ENSDART00000084738
ppp1r27a
protein phosphatase 1, regulatory subunit 27a
chr3_-_60929921 1.87 ENSDART00000055064
pvalb8
parvalbumin 8
chr1_-_9387290 1.77 ENSDART00000135522
ENSDART00000135676
fga
fibrinogen alpha chain
chr7_+_50828119 1.75 ENSDART00000108738
col4a5
collagen, type IV, alpha 5 (Alport syndrome)
chr12_-_4351401 1.74

chr5_-_1698166 1.66 ENSDART00000073462
rplp0
ribosomal protein, large, P0
chr7_-_33558939 1.66 ENSDART00000074729
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr2_+_49837788 1.62 ENSDART00000108861
sema4e
semaphorin 4e
chr1_-_25272318 1.60 ENSDART00000134192
synpo2b
synaptopodin 2b
chr23_+_45020761 1.50 ENSDART00000159104
atp1b2a
ATPase, Na+/K+ transporting, beta 2a polypeptide
chr16_+_7213161 1.50 ENSDART00000168830
ENSDART00000168274
ENSDART00000160383
ENSDART00000163281
bmper
BMP binding endothelial regulator
chr12_-_4033069 1.50 ENSDART00000042200
aldoab
aldolase a, fructose-bisphosphate, b
chr19_-_2399429 1.45 ENSDART00000043595
twist1a
twist family bHLH transcription factor 1a
chr11_+_14618598 1.44 ENSDART00000109308
si:ch73-60h1.1
si:ch73-60h1.1
chr22_+_24131239 1.43 ENSDART00000159165
b3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr3_+_30790513 1.41 ENSDART00000130422
cldni
claudin i
chr23_-_7283514 1.40 ENSDART00000156369
CR589876.1
ENSDARG00000096997
chr4_+_21485280 1.38 ENSDART00000066896
syt1a
synaptotagmin Ia
chr4_-_12863235 1.38 ENSDART00000080536
hmga2
high mobility group AT-hook 2
KN150640v1_+_5728 1.37

chr13_-_28177612 1.31 ENSDART00000045351
lbx1a
ladybird homeobox 1a
chr10_-_27261937 1.28

chr10_+_9052152 1.28 ENSDART00000139466
itga2.2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2
chr14_-_9114872 1.28 ENSDART00000081158
sh3bgrl
SH3 domain binding glutamate-rich protein like
chr8_-_38357549 1.25 ENSDART00000129597
sorbs3
sorbin and SH3 domain containing 3
KN149707v1_+_4014 1.25 ENSDART00000168516
cdo1
cysteine dioxygenase, type I
chr22_-_951880 1.25 ENSDART00000105895
ENSDART00000172206
cacna1sa
calcium channel, voltage-dependent, L type, alpha 1S subunit, a
chr19_+_42183946 1.23 ENSDART00000087096
tinagl1
tubulointerstitial nephritis antigen-like 1
chr9_-_53220424 1.22

chr2_-_55971357 1.21 ENSDART00000154701
ENSDART00000154107
si:ch211-178n15.1
si:ch211-178n15.1
chr4_-_876235 1.19

chr23_+_14461509 1.19 ENSDART00000143618
birc7
baculoviral IAP repeat containing 7
chr8_+_13465718 1.17 ENSDART00000034740
fut9d
fucosyltransferase 9d
chr22_+_10172134 1.16 ENSDART00000132641
pdhb
pyruvate dehydrogenase (lipoamide) beta
chr16_-_24602919 1.15 ENSDART00000147478
cadm4
cell adhesion molecule 4
chr22_+_30060679 1.14 ENSDART00000142529
si:dkey-286j15.1
si:dkey-286j15.1
chr3_-_60930025 1.13 ENSDART00000055064
pvalb8
parvalbumin 8
chr4_-_12862869 1.12 ENSDART00000080536
hmga2
high mobility group AT-hook 2
chr8_+_15968469 1.11 ENSDART00000134787
elavl4
ELAV like neuron-specific RNA binding protein 4
chr2_-_59013059 1.11

chr21_-_36338704 1.09 ENSDART00000157826
mpp1
membrane protein, palmitoylated 1
chr11_-_32461160 1.07 ENSDART00000155592
pcdh17
protocadherin 17
chr7_+_16583234 1.07 ENSDART00000173580
nav2a
neuron navigator 2a
chr4_+_14972481 1.06 ENSDART00000005985
smo
smoothened, frizzled class receptor
chr23_+_29962550 1.06 ENSDART00000149378
mxra8b
matrix-remodelling associated 8b
chr14_-_549816 1.05 ENSDART00000168951
fgf2
fibroblast growth factor 2
chr7_-_33558771 1.05 ENSDART00000074729
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr21_-_36338514 1.04 ENSDART00000157826
mpp1
membrane protein, palmitoylated 1
chr18_+_5456221 1.04

chr9_-_22371512 1.04 ENSDART00000101809
crygm2d6
crystallin, gamma M2d6
chr1_-_14642681 1.04 ENSDART00000109970
dlc1
DLC1 Rho GTPase activating protein
chr10_+_10830549 1.04 ENSDART00000101077
ENSDART00000139143
ptgdsa
prostaglandin D2 synthase a
chr1_+_18842158 1.03 ENSDART00000103089
ENSDARG00000070320
ENSDARG00000070320
chr12_+_16403743 1.02 ENSDART00000058665
kif20bb
kinesin family member 20Bb
chr1_-_18110990 1.02 ENSDART00000020970
pgm2
phosphoglucomutase 2
chr4_+_11312432 1.00 ENSDART00000051792
sema3aa
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa
chr7_+_58384379 1.00 ENSDART00000052332
penkb
proenkephalin b
chr24_-_14567403 0.98 ENSDART00000131830
jph1a
junctophilin 1a
chr20_-_158899 0.98 ENSDART00000131635
slc16a10
solute carrier family 16 (aromatic amino acid transporter), member 10
chr16_-_10089440 0.98 ENSDART00000066372
id4
inhibitor of DNA binding 4
chr6_+_58549236 0.96 ENSDART00000157018
stmn3
stathmin-like 3
chr5_-_43896815 0.96 ENSDART00000110076
gas1a
growth arrest-specific 1a
chr1_+_44660098 0.96 ENSDART00000145486
si:ch211-243a20.3
si:ch211-243a20.3
chr22_+_24131297 0.96 ENSDART00000159165
b3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr2_+_11902170 0.95 ENSDART00000138562
greb1l
growth regulation by estrogen in breast cancer-like
chr8_-_38308535 0.95

chr16_+_12101666 0.94 ENSDART00000143442
p3h3
prolyl 3-hydroxylase 3
chr11_-_13069266 0.92 ENSDART00000169052
elovl1b
ELOVL fatty acid elongase 1b
chr19_+_17941678 0.91 ENSDART00000124597
nr1d2b
nuclear receptor subfamily 1, group D, member 2b
chr7_-_52848084 0.90 ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr1_-_21987718 0.90 ENSDART00000128918
fgfbp1b
fibroblast growth factor binding protein 1b
chr1_-_30298698 0.89

chr20_+_23339698 0.89 ENSDART00000074167
ociad2
OCIA domain containing 2
chr6_+_251026 0.88 ENSDART00000042970
atf4a
activating transcription factor 4a
chr12_-_10372055 0.87 ENSDART00000052001
eef2k
eukaryotic elongation factor 2 kinase
chr10_+_9575 0.87

chr4_-_19027117 0.86 ENSDART00000166160
si:dkey-31f5.11
si:dkey-31f5.11
chr4_+_9393501 0.83 ENSDART00000092013
tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr4_+_14972708 0.83 ENSDART00000005985
smo
smoothened, frizzled class receptor
chr1_+_44044807 0.83 ENSDART00000133926
ENSDART00000049701
p2rx3b
purinergic receptor P2X, ligand-gated ion channel, 3b
chr12_+_30471689 0.82 ENSDART00000124920
nrap
nebulin-related anchoring protein
chr14_-_43191278 0.81 ENSDART00000169615
adh5
alcohol dehydrogenase 5
chr9_-_10561062 0.80 ENSDART00000175269
thsd7ba
thrombospondin, type I, domain containing 7Ba
chr24_+_30343717 0.79 ENSDART00000162377
FP085414.1
ENSDARG00000100270
chr16_-_34304851 0.79 ENSDART00000145485
phactr4b
phosphatase and actin regulator 4b
chr21_+_44586326 0.79

chr16_+_29109050 0.78 ENSDART00000122681
CR848841.1
Nestin
chr18_+_40364675 0.78 ENSDART00000098791
ENSDART00000049171
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr6_-_31246730 0.78 ENSDART00000079173
lepr
leptin receptor
chr5_-_71505131 0.77 ENSDART00000037691
tbx5a
T-box 5a
chr3_+_27684309 0.77

chr1_+_54403123 0.76 ENSDART00000152654
lgalsla
lectin, galactoside-binding-like a
chr5_-_43896757 0.76 ENSDART00000110076
gas1a
growth arrest-specific 1a
chr20_-_25727145 0.76 ENSDART00000126716
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr3_+_16080070 0.76 ENSDART00000137396
rpl19
ribosomal protein L19
chr19_-_15951003 0.76 ENSDART00000133059
cited4a
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
chr19_+_14197118 0.75 ENSDART00000166230
tpbga
trophoblast glycoprotein a
chr16_+_10974655 0.74

chr8_+_20125687 0.74 ENSDART00000124809
acsbg2
acyl-CoA synthetase bubblegum family member 2
chr19_-_28382815 0.74 ENSDART00000110016
ube2ql1
ubiquitin-conjugating enzyme E2Q family-like 1
chr19_+_32679258 0.74

chr8_-_15071283 0.74

chr11_-_44280978 0.73 ENSDART00000099568
gpr137bb
G protein-coupled receptor 137Bb
chr13_-_40190349 0.73 ENSDART00000009343
pyroxd2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr2_+_37985514 0.72 ENSDART00000149224
apol1
apolipoprotein L, 1
chr13_-_219661 0.72 ENSDART00000133731
si:ch1073-291c23.2
si:ch1073-291c23.2
chr4_+_13932849 0.72 ENSDART00000141742
pphln1
periphilin 1
chr11_-_1792616 0.71

chr14_+_34207218 0.71 ENSDART00000135608
gabrp
gamma-aminobutyric acid (GABA) A receptor, pi
KN150361v1_-_15974 0.70 ENSDART00000167588
ENSDARG00000099568
ENSDARG00000099568
chr19_-_34508557 0.70 ENSDART00000160495
si:dkey-184p18.2
si:dkey-184p18.2
chr20_+_1724609 0.69

chr19_+_32679320 0.69

chr12_+_5495284 0.69 ENSDART00000114637
ace
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr16_-_21981065 0.69 ENSDART00000078858
si:ch73-86n18.1
si:ch73-86n18.1
chr25_-_255242 0.68

chr20_+_27748136 0.68 ENSDART00000141697
mthfd1a
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1a, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
chr21_+_19889712 0.66 ENSDART00000147294
tnksa
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase a
chr6_+_9185750 0.66 ENSDART00000161036
kalrnb
kalirin RhoGEF kinase b
chr6_+_41257803 0.65 ENSDART00000042683
cadpsb
Ca2+-dependent activator protein for secretion b
chr18_+_36825511 0.65 ENSDART00000098958
ttc9b
tetratricopeptide repeat domain 9B
chr7_-_33559032 0.63 ENSDART00000074729
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr6_-_16156494 0.63

chr14_-_2278018 0.62 ENSDART00000125674
pcdh2ab9
protocadherin 2 alpha b 9
chr8_-_26848577 0.62

chr7_+_50828247 0.60 ENSDART00000174236
col4a5
collagen, type IV, alpha 5 (Alport syndrome)
chr9_+_21725007 0.60 ENSDART00000045093
arhgef7a
Rho guanine nucleotide exchange factor (GEF) 7a
chr17_+_48999061 0.59 ENSDART00000177390
tiam2a
T-cell lymphoma invasion and metastasis 2a
chr19_-_28192439 0.59 ENSDART00000135348
adcy2b
adenylate cyclase 2b (brain)
chr7_-_26331734 0.59

chr22_-_16971035 0.58 ENSDART00000090237
nfia
nuclear factor I/A
chr20_-_54645287 0.57 ENSDART00000153389
yy1b
YY1 transcription factor b
chr24_+_26944182 0.57 ENSDART00000089541
dip2ca
disco-interacting protein 2 homolog Ca
chr25_-_34638406 0.56 ENSDART00000123853
hist1h4l
histone 1, H4, like
chr18_-_11426 0.56 ENSDART00000159781
WHAMM
WAS protein homolog associated with actin, golgi membranes and microtubules
chr2_-_39052185 0.56 ENSDART00000048838
rbp2b
retinol binding protein 2b, cellular
chr16_-_25370472 0.55 ENSDART00000154543
prelid3a
PRELI domain containing 3A
chr13_+_28382422 0.55 ENSDART00000043117
fbxw4
F-box and WD repeat domain containing 4
chr6_-_60109646 0.55 ENSDART00000057463
ENSDART00000169188
pmepa1
prostate transmembrane protein, androgen induced 1
chr10_+_17490443 0.54

chr6_+_37881015 0.52 ENSDART00000087311
oca2
oculocutaneous albinism II
chr19_+_42491631 0.52 ENSDART00000150949
nfyc
nuclear transcription factor Y, gamma
chr17_-_37040941 0.51 ENSDART00000126823
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr17_-_120568 0.51

chr18_+_19783732 0.51 ENSDART00000043455
smad3b
SMAD family member 3b
chr22_-_16970979 0.50 ENSDART00000090237
nfia
nuclear factor I/A
chr12_-_33792377 0.50 ENSDART00000153280
sema4gb
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Gb
chr3_+_33209227 0.50 ENSDART00000128786
pyya
peptide YYa
chr15_-_33782909 0.49 ENSDART00000167705
stard13b
StAR-related lipid transfer (START) domain containing 13b
chr1_+_44239727 0.49 ENSDART00000141145
si:dkey-9i23.16
si:dkey-9i23.16
chr17_-_120755 0.49

chr24_+_30343687 0.49 ENSDART00000162377
FP085414.1
ENSDARG00000100270
chr12_-_3320438 0.49

chr23_+_33457343 0.48 ENSDART00000114423
rapgef3
Rap guanine nucleotide exchange factor (GEF) 3
chr17_-_117828 0.47

chr15_-_16271208 0.47

chr17_+_11961595 0.47

chr14_-_35985200 0.46 ENSDART00000172783
egf
epidermal growth factor
chr15_+_29190162 0.46 ENSDART00000105222
zgc:101731
zgc:101731
chr22_-_16971180 0.46 ENSDART00000090237
nfia
nuclear factor I/A
chr14_-_9274939 0.46

chr12_+_272930 0.46 ENSDART00000152639
ict1
immature colon carcinoma transcript 1
chr12_-_21918058 0.46 ENSDART00000153187
thrab
thyroid hormone receptor alpha b
chr8_+_22559432 0.46

chr4_-_16344835 0.45 ENSDART00000134449
epyc
epiphycan
chr5_+_22173976 0.45 ENSDART00000142112
vma21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr3_+_22447812 0.44 ENSDART00000112270
tanc2a
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2a
chr3_+_28371725 0.43 ENSDART00000151081
sept12
septin 12
chr4_-_12863112 0.43 ENSDART00000080536
hmga2
high mobility group AT-hook 2
chr8_+_7655655 0.43 ENSDART00000170184
fgd1
FYVE, RhoGEF and PH domain containing 1
chr8_+_30654835 0.43 ENSDART00000138750
adora2aa
adenosine A2a receptor a
chr1_+_52308366 0.43 ENSDART00000108492
inpp4b
inositol polyphosphate-4-phosphatase type II B
chr11_-_16067646 0.43

chr9_-_55878647 0.42

chr14_-_2451650 0.41 ENSDART00000111748
pcdhb
protocadherin b
chr12_+_3686860 0.41 ENSDART00000152482
pagr1
PAXIP1 associated glutamate-rich protein 1
KN150640v1_+_5907 0.41

chr13_-_24248675 0.40 ENSDART00000046360
rhoua
ras homolog family member Ua
chr21_+_5293086 0.40

chr5_-_44243476 0.40 ENSDART00000161408
fbp1a
fructose-1,6-bisphosphatase 1a
chr11_+_44922098 0.40 ENSDART00000172999
mafgb
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Gb
chr23_+_22408855 0.39 ENSDART00000147696
rap1gap
RAP1 GTPase activating protein
chr15_+_9351211 0.39 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr12_-_31342432 0.39 ENSDART00000148603
acsl5
acyl-CoA synthetase long-chain family member 5
chr16_-_20084451 0.39 ENSDART00000079155
hdac9b
histone deacetylase 9b
chr2_-_44429891 0.39 ENSDART00000163040
ENSDART00000056372
ENSDART00000109251
ENSDART00000166923
ENSDART00000132682
mpz
myelin protein zero
chr10_-_29386085 0.39 ENSDART00000022605
tmem126a
transmembrane protein 126A
chr17_+_42003279 0.38 ENSDART00000111537
kiz
kizuna centrosomal protein
chr18_+_45199548 0.38

chr2_+_38244259 0.38 ENSDART00000131384
si:ch211-14a17.11
si:ch211-14a17.11
chr24_-_25021505 0.37 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
KN149959v1_+_21015 0.37 ENSDART00000161495
CABZ01078608.1
ENSDARG00000105028
chr14_-_30467807 0.37 ENSDART00000173262
prss23
protease, serine, 23
chr11_+_14373731 0.37 ENSDART00000161879
BX571942.1
ENSDARG00000099220
chr7_-_24119645 0.37 ENSDART00000141769
ptgr1
prostaglandin reductase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0034433 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372) steroid esterification(GO:0034433) sterol esterification(GO:0034434) cholesterol esterification(GO:0034435) reverse cholesterol transport(GO:0043691) positive regulation of steroid metabolic process(GO:0045940)
0.6 3.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.4 1.2 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.4 1.9 GO:0048745 smooth muscle tissue development(GO:0048745) arterial endothelial cell fate commitment(GO:0060844)
0.3 1.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3 1.6 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.3 2.4 GO:0007412 axon target recognition(GO:0007412)
0.3 0.8 GO:0003294 atrial ventricular junction remodeling(GO:0003294)
0.2 0.7 GO:0097355 protein localization to heterochromatin(GO:0097355)
0.2 0.7 GO:0032212 positive regulation of telomere maintenance via telomerase(GO:0032212) positive regulation of telomere maintenance via telomere lengthening(GO:1904358)
0.2 1.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.2 0.8 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.2 1.0 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.2 1.1 GO:0003232 bulbus arteriosus development(GO:0003232)
0.2 1.1 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.2 0.7 GO:0002762 negative regulation of myeloid leukocyte differentiation(GO:0002762)
0.2 0.9 GO:0003379 establishment of cell polarity involved in gastrulation cell migration(GO:0003379) cell-cell adhesion involved in gastrulation(GO:0070586)
0.2 1.9 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 2.4 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 1.2 GO:0036065 fucosylation(GO:0036065)
0.2 0.8 GO:0046292 formaldehyde metabolic process(GO:0046292) formaldehyde catabolic process(GO:0046294)
0.2 1.8 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 0.5 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154)
0.2 0.5 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.9 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1 0.8 GO:0033198 response to ATP(GO:0033198)
0.1 1.0 GO:0030323 respiratory tube development(GO:0030323) lung development(GO:0030324)
0.1 0.7 GO:1990504 dense core granule exocytosis(GO:1990504)
0.1 0.4 GO:2000193 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) regulation of organic acid transport(GO:0032890) positive regulation of organic acid transport(GO:0032892) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transport(GO:1903793) regulation of anion transmembrane transport(GO:1903959) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.1 0.6 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 0.8 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.3 GO:0019242 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.6 GO:0010990 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1 1.0 GO:0003307 regulation of Wnt signaling pathway involved in heart development(GO:0003307)
0.1 0.4 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520) regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.1 1.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.4 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 1.7 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.6 GO:0061469 regulation of cell proliferation involved in tissue homeostasis(GO:0060784) regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 1.5 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.5 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.1 1.6 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 0.7 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.4 GO:0003160 endocardium morphogenesis(GO:0003160)
0.1 1.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.1 0.6 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.6 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 1.4 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 1.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.8 GO:0009749 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.0 0.7 GO:0035775 pronephric glomerulus morphogenesis(GO:0035775)
0.0 1.5 GO:0014029 neural crest formation(GO:0014029)
0.0 0.9 GO:0032963 collagen metabolic process(GO:0032963) multicellular organismal macromolecule metabolic process(GO:0044259)
0.0 1.1 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 1.7 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0061011 hepatic duct development(GO:0061011) hepatocyte proliferation(GO:0072574) epithelial cell proliferation involved in liver morphogenesis(GO:0072575)
0.0 0.5 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.4 GO:0036302 atrioventricular canal development(GO:0036302)
0.0 0.2 GO:0021698 cerebellar Purkinje cell layer structural organization(GO:0021693) cerebellar cortex structural organization(GO:0021698) nuclear mRNA surveillance of mRNA 3'-end processing(GO:0071031) nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription(GO:0071049)
0.0 0.3 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.9 GO:0048794 swim bladder development(GO:0048794)
0.0 1.5 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.5 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.2 GO:0060282 cGMP-mediated signaling(GO:0019934) positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:0015961 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961)
0.0 1.3 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.3 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.0 1.3 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0006272 leading strand elongation(GO:0006272)
0.0 0.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.4 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.4 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.8 GO:0070509 calcium ion import(GO:0070509)
0.0 0.5 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 1.0 GO:0006006 glucose metabolic process(GO:0006006)
0.0 1.0 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 1.4 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 1.3 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.4 GO:0009755 hormone-mediated signaling pathway(GO:0009755)
0.0 1.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:0042627 chylomicron(GO:0042627)
0.6 1.8 GO:0005577 fibrinogen complex(GO:0005577)
0.4 1.7 GO:0042584 chromaffin granule membrane(GO:0042584)
0.4 1.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.3 1.0 GO:0030314 junctional membrane complex(GO:0030314)
0.3 0.9 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.2 1.5 GO:0098533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.1 0.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 0.9 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 0.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.7 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 1.0 GO:0043679 axon terminus(GO:0043679)
0.0 0.7 GO:0045180 basal cortex(GO:0045180)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 1.3 GO:0008305 integrin complex(GO:0008305)
0.0 2.3 GO:0005604 basement membrane(GO:0005604)
0.0 1.1 GO:0043204 perikaryon(GO:0043204)
0.0 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.4 GO:0043209 myelin sheath(GO:0043209)
0.0 2.4 GO:0030018 Z disc(GO:0030018)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.4 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.0 0.3 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 1.4 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.4 GO:0030027 lamellipodium(GO:0030027)
0.0 1.0 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 6.8 GO:0005615 extracellular space(GO:0005615)
0.0 0.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0008142 oxysterol binding(GO:0008142)
0.4 1.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.3 1.7 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.3 1.2 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.3 0.8 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 0.9 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.2 0.7 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.2 1.0 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.2 2.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 1.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.8 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.6 GO:0004016 adenylate cyclase activity(GO:0004016)
0.1 0.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 0.6 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.8 GO:0035381 purinergic nucleotide receptor activity(GO:0001614) extracellular ATP-gated cation channel activity(GO:0004931) nucleotide receptor activity(GO:0016502) ATP-gated ion channel activity(GO:0035381)
0.1 0.4 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 3.4 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.6 GO:0035586 G-protein coupled adenosine receptor activity(GO:0001609) purinergic receptor activity(GO:0035586)
0.1 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.1 1.0 GO:0031628 opioid receptor binding(GO:0031628)
0.1 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 1.5 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.3 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.2 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.1 3.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 0.7 GO:0016405 CoA-ligase activity(GO:0016405)
0.1 1.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.2 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 1.0 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.1 0.4 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 1.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.5 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.8 GO:0019211 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 2.4 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 1.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.7 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 1.9 GO:0019902 phosphatase binding(GO:0019902)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.4 GO:0019203 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.0 0.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0032977 membrane insertase activity(GO:0032977)
0.0 0.8 GO:0019955 cytokine binding(GO:0019955)
0.0 0.3 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.1 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.0 0.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.9 GO:0019838 growth factor binding(GO:0019838)
0.0 8.4 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.0 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 1.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 1.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 0.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.7 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.3 1.8 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 0.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 1.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.9 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 2.4 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.7 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 2.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.6 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins