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Results for rela_nfkb1

Z-value: 0.66

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Transcription factors associated with rela_nfkb1

Gene Symbol Gene ID Gene Info
rela
ENSDARG00000098696 v-rel avian reticuloendotheliosis viral oncogene homolog A
nfkb1
ENSDARG00000105261 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
reladr10_dc_chr7_-_667744_6678110.514.4e-02Click!
nfkb1dr10_dc_chr14_-_50657786_506578540.185.1e-01Click!

Activity profile of rela_nfkb1 motif

Sorted Z-values of rela_nfkb1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of rela_nfkb1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr18_-_16934961 1.30 ENSDART00000122102
wee1
WEE1 G2 checkpoint kinase
chr11_+_6446302 1.29 ENSDART00000140707
ENSDART00000036939
gadd45ba
growth arrest and DNA-damage-inducible, beta a
chr11_+_34788205 1.24 ENSDART00000124800
fam212aa
family with sequence similarity 212, member Aa
chr20_-_35173530 1.00 ENSDART00000019196
lft1
lefty1
chr8_-_1669966 0.95

chr23_+_10412852 0.88 ENSDART00000142595
krt18
keratin 18
chr12_-_30645906 0.84 ENSDART00000066257
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr11_-_19414624 0.81 ENSDART00000157847
atxn7
ataxin 7
chr16_+_4288700 0.81 ENSDART00000159694
inpp5b
inositol polyphosphate-5-phosphatase B
KN149832v1_+_6032 0.80

chr2_+_17112049 0.78 ENSDART00000125647
tfa
transferrin-a
chr5_+_50355421 0.74 ENSDART00000074638
ankrd31
ankyrin repeat domain 31
chr9_-_26776407 0.70

chr7_+_1228387 0.69 ENSDART00000143762
khnyn
KH and NYN domain containing
chr20_+_16982314 0.68 ENSDART00000146625
nfkbiaa
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr5_+_36431907 0.68 ENSDART00000045036
nfkbib
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr22_+_30234718 0.68 ENSDART00000172496
add3a
adducin 3 (gamma) a
KN150670v1_-_72156 0.67

chr3_-_26393945 0.66 ENSDART00000087118
xylt1
xylosyltransferase I
chr12_+_34631310 0.65 ENSDART00000169634
si:dkey-21c1.8
si:dkey-21c1.8
chr2_-_51231808 0.64 ENSDART00000170470
ghrhra
growth hormone releasing hormone receptor a
chr12_+_34631232 0.61 ENSDART00000169634
si:dkey-21c1.8
si:dkey-21c1.8
chr21_-_485916 0.59 ENSDART00000110297
klf4
Kruppel-like factor 4
chr25_+_24520476 0.58

chr15_+_27431469 0.58 ENSDART00000122101
tbx2b
T-box 2b
chr1_+_9426040 0.57 ENSDART00000080576
lratb
lecithin retinol acyltransferase b (phosphatidylcholine-retinol O-acyltransferase)
chr13_-_33696425 0.56 ENSDART00000143703
flrt3
fibronectin leucine rich transmembrane 3
chr4_-_25496215 0.56 ENSDART00000041402
pfkfb3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr7_-_667744 0.52 ENSDART00000159359
rela
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr3_-_24925189 0.52 ENSDART00000156459
ep300b
E1A binding protein p300 b
chr13_+_1051015 0.51 ENSDART00000033528
tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr12_-_18839556 0.51 ENSDART00000172574
ep300a
E1A binding protein p300 a
chr7_-_48392300 0.51

chr3_+_22412059 0.50

chr8_+_22334642 0.50 ENSDART00000146457
ENSDART00000142883
zgc:153631
zgc:153631
chr7_+_1228148 0.49 ENSDART00000143762
khnyn
KH and NYN domain containing
chr4_+_29209923 0.49 ENSDART00000168709
ENSDARG00000104041
ENSDARG00000104041
chr16_+_1227270 0.47

chr20_-_21775455 0.45

chr11_-_5868257 0.44 ENSDART00000104360
gamt
guanidinoacetate N-methyltransferase
chr3_+_35276575 0.43 ENSDART00000102994
rbbp6
retinoblastoma binding protein 6
chr4_-_12796590 0.42 ENSDART00000075127
b2m
beta-2-microglobulin
chr11_+_8558222 0.41 ENSDART00000169141
ENSDART00000126523
tbl1xr1a
transducin (beta)-like 1 X-linked receptor 1a
chr8_+_28240085 0.41 ENSDART00000110857
fam212b
family with sequence similarity 212, member B
chr7_+_15623852 0.41 ENSDART00000161608
pax6b
paired box 6b
chr14_-_30556788 0.39 ENSDART00000087918
slc7a3b
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3b
chr11_-_7129695 0.39 ENSDART00000016472
bmp7a
bone morphogenetic protein 7a
chr3_-_10342940 0.39 ENSDART00000124419
BX539325.2
ENSDARG00000101154
chr8_+_7740132 0.38 ENSDART00000171325
tfe3a
transcription factor binding to IGHM enhancer 3a
chr16_+_24766043 0.37 ENSDART00000114304
ywhabl
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like
chr16_+_49796978 0.37 ENSDART00000157100
ube2e2
ubiquitin-conjugating enzyme E2E 2
chr3_+_54876680 0.35 ENSDART00000111585
hbbe1.3
hemoglobin, beta embryonic 1.3
chr6_+_1895734 0.35 ENSDART00000109679
quo
quattro
chr13_-_35908743 0.34 ENSDART00000133565
si:dkey-157l19.2
si:dkey-157l19.2
chr7_-_46509291 0.34 ENSDART00000173891
tshz3b
teashirt zinc finger homeobox 3b
chr2_-_39709905 0.33 ENSDART00000147821
spsb4a
splA/ryanodine receptor domain and SOCS box containing 4a
chr13_-_24181106 0.33 ENSDART00000004420
rab4a
RAB4a, member RAS oncogene family
chr2_+_58658615 0.33

chr19_-_11290766 0.33 ENSDART00000044426
si:dkey-240h12.4
si:dkey-240h12.4
chr9_+_55999688 0.33 ENSDART00000172063
edar
ectodysplasin A receptor
chr23_+_6043862 0.33

chr17_+_48999061 0.32 ENSDART00000177390
tiam2a
T-cell lymphoma invasion and metastasis 2a
chr11_+_26138359 0.32 ENSDART00000087652
cpne1
copine I
chr2_-_3202918 0.31

chr4_+_119964 0.30 ENSDART00000177177
ENSDART00000159996
tbk1
TANK-binding kinase 1
chr6_+_58921655 0.30 ENSDART00000083628
ddit3
DNA-damage-inducible transcript 3
chr23_-_2084541 0.30 ENSDART00000091532
ndnf
neuron-derived neurotrophic factor
chr1_+_44137973 0.29

chr5_-_43896815 0.29 ENSDART00000110076
gas1a
growth arrest-specific 1a
chr21_+_28921734 0.29 ENSDART00000166575
ppp3ca
protein phosphatase 3, catalytic subunit, alpha isozyme
chr2_+_25106923 0.29 ENSDART00000078866
ifi30
interferon, gamma-inducible protein 30
chr22_-_20316908 0.29 ENSDART00000165667
tcf3b
transcription factor 3b
chr11_+_30049795 0.28

chr24_-_15313198 0.28

chr16_-_31835463 0.28 ENSDART00000148389
chd4b
chromodomain helicase DNA binding protein 4b
chr19_+_43524566 0.27 ENSDART00000129362
eef1a1l2
eukaryotic translation elongation factor 1 alpha 1, like 2
chr5_+_23582396 0.27 ENSDART00000051549
ENSDART00000135934
tp53
tumor protein p53
chr17_+_1950129 0.27 ENSDART00000110529
bub1bb
BUB1 mitotic checkpoint serine/threonine kinase Bb
chr14_-_4014025 0.27 ENSDART00000157782
irf2
interferon regulatory factor 2
chr25_+_5162045 0.27 ENSDART00000169540
ENSDARG00000101164
ENSDARG00000101164
chr22_+_470536 0.26 ENSDART00000135403
nuak2
NUAK family, SNF1-like kinase, 2
chr12_+_36796886 0.26 ENSDART00000125900
hs3st3b1b
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1b
chr21_+_30900987 0.25 ENSDART00000022562
rhogb
ras homolog family member Gb
chr15_-_6979997 0.25 ENSDART00000169944
si:ch73-311h14.2
si:ch73-311h14.2
chr24_+_34227202 0.25 ENSDART00000105572
gbx1
gastrulation brain homeobox 1
KN150680v1_+_10854 0.25

chr16_+_10666588 0.25 ENSDART00000091241
si:ch73-22o12.1
si:ch73-22o12.1
chr13_-_4238408 0.24 ENSDART00000124716
si:dkeyp-121d4.3
si:dkeyp-121d4.3
chr18_-_11707 0.24 ENSDART00000159781
WHAMM
WAS protein homolog associated with actin, golgi membranes and microtubules
chr8_-_38444845 0.24 ENSDART00000075989
inpp5l
inositol polyphosphate-5-phosphatase L
chr16_-_16682692 0.24 ENSDART00000059841
si:ch211-257p13.3
si:ch211-257p13.3
chr17_+_48999102 0.24 ENSDART00000177390
tiam2a
T-cell lymphoma invasion and metastasis 2a
chr7_+_15623685 0.24 ENSDART00000146704
pax6b
paired box 6b
chr20_-_35173500 0.23 ENSDART00000019196
lft1
lefty1
chr24_-_4941954 0.23 ENSDART00000127597
zic1
zic family member 1 (odd-paired homolog, Drosophila)
chr14_-_30739765 0.23 ENSDART00000173282
mbnl3
muscleblind-like splicing regulator 3
chr6_+_33556031 0.23 ENSDART00000147625
pik3r3b
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr2_+_44067425 0.22 ENSDART00000123673
si:ch211-195h23.3
si:ch211-195h23.3
chr20_-_6153133 0.22 ENSDART00000013343
b4galt6
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr6_+_3703684 0.22 ENSDART00000013743
gorasp2
golgi reassembly stacking protein 2
chr22_-_613948 0.22 ENSDART00000148692
apobec2a
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a
chr12_+_27370834 0.21 ENSDART00000105661
meox1
mesenchyme homeobox 1
chr16_-_36022327 0.21 ENSDART00000172252
eva1ba
eva-1 homolog Ba (C. elegans)
chr19_-_35828807 0.21

chr18_-_18554151 0.21 ENSDART00000126460
il34
interleukin 34
chr25_+_3221696 0.21 ENSDART00000104888
slc35b4
solute carrier family 35, member B4
chr2_+_2583068 0.21

chr9_-_34129128 0.21

chr15_-_33782909 0.20 ENSDART00000167705
stard13b
StAR-related lipid transfer (START) domain containing 13b
chr2_-_3203802 0.20 ENSDART00000105818
guk1a
guanylate kinase 1a
chr7_+_40183670 0.20 ENSDART00000173916
ptprn2
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr7_+_40879017 0.20

chr13_+_14873339 0.20 ENSDART00000057810
emx1
empty spiracles homeobox 1
chr8_+_42992323 0.20 ENSDART00000048819
rassf2a
Ras association (RalGDS/AF-6) domain family member 2a
chr7_-_38590391 0.20 ENSDART00000037361
ENSDART00000173629
ENSDART00000173953
phf21aa
PHD finger protein 21Aa
chr8_+_25984588 0.20

chr14_+_38506051 0.19 ENSDART00000144599
hnrnpa0b
heterogeneous nuclear ribonucleoprotein A0b
chr5_+_20596549 0.19 ENSDART00000051586
hs3st1l2
heparan sulfate (glucosamine) 3-O-sulfotransferase 1-like 2
chr14_+_38505790 0.19 ENSDART00000144599
hnrnpa0b
heterogeneous nuclear ribonucleoprotein A0b
chr11_-_35501227 0.19 ENSDART00000026017
bhlhe40
basic helix-loop-helix family, member e40
chr3_-_7769397 0.18

chr15_+_24821561 0.18 ENSDART00000156424
cpda
carboxypeptidase D, a
chr21_-_30378764 0.18 ENSDART00000136247
grpel2
GrpE-like 2, mitochondrial
chr5_+_36431824 0.18 ENSDART00000045036
nfkbib
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr6_-_53333648 0.18 ENSDART00000172465
gnb1b
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr16_+_13964949 0.18 ENSDART00000143983
zgc:174888
zgc:174888
chr11_+_40280114 0.18 ENSDART00000175424
mmel1
membrane metallo-endopeptidase-like 1
chr4_+_13811932 0.18 ENSDART00000067168
pdzrn4
PDZ domain containing ring finger 4
chr13_-_35908796 0.18 ENSDART00000084929
si:dkey-157l19.2
si:dkey-157l19.2
chr5_+_10789834 0.18

chr2_-_42011586 0.18 ENSDART00000045763
keap1a
kelch-like ECH-associated protein 1a
chr4_+_2210362 0.18 ENSDART00000067427
yeats4
YEATS domain containing 4
chr5_-_43896757 0.17 ENSDART00000110076
gas1a
growth arrest-specific 1a
chr6_-_35326559 0.17 ENSDART00000114960
nos1apa
nitric oxide synthase 1 (neuronal) adaptor protein a
chr7_+_16583234 0.17 ENSDART00000173580
nav2a
neuron navigator 2a
chr14_+_150214 0.17 ENSDART00000162480
mcm7
minichromosome maintenance complex component 7
chr3_+_23587156 0.17

chr13_+_35213326 0.17 ENSDART00000019323
jag1b
jagged 1b
KN150183v1_+_12947 0.17

chr23_+_19775308 0.17 ENSDART00000104425
dnase1l1
deoxyribonuclease I-like 1
chr18_+_22285979 0.17

chr2_+_42342148 0.17 ENSDART00000144716
cavin4a
caveolae associated protein 4a
chr7_+_61770242 0.17 ENSDART00000092580
rbpjb
recombination signal binding protein for immunoglobulin kappa J region b
chr7_+_39487676 0.17 ENSDART00000111278
sorcs2
sortilin-related VPS10 domain containing receptor 2
chr10_+_10393377 0.16 ENSDART00000109432
cercam
cerebral endothelial cell adhesion molecule
chr8_+_53390978 0.16 ENSDART00000130104
gnb1a
guanine nucleotide binding protein (G protein), beta polypeptide 1a
chr16_-_13914368 0.16

chr20_-_51494625 0.16 ENSDART00000098833
nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr7_-_46509218 0.15 ENSDART00000173891
tshz3b
teashirt zinc finger homeobox 3b
chr21_+_3556841 0.15

chr21_-_44013995 0.15 ENSDART00000028960
ndufa2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
chr18_+_730277 0.15 ENSDART00000159846
prtga
protogenin homolog a (Gallus gallus)
chr16_+_12740993 0.15 ENSDART00000128497
nat14
N-acetyltransferase 14 (GCN5-related, putative)
chr25_+_16549708 0.14 ENSDART00000110426
cecr2
cat eye syndrome chromosome region, candidate 2
chr9_+_13762263 0.14 ENSDART00000141314
ENSDART00000138254
abi2a
abl-interactor 2a
chr18_-_15132837 0.14 ENSDART00000172273
btbd11b
BTB (POZ) domain containing 11b
chr7_-_73620490 0.14 ENSDART00000158891
ENSDART00000111622
FP236812.3
ENSDARG00000079652
chr3_+_22411884 0.14

chr19_-_32913075 0.14 ENSDART00000052104
fuca1.1
fucosidase, alpha-L- 1, tissue, tandem duplicate 1
chr11_-_32502472 0.14

chr15_-_27431216 0.14 ENSDART00000155933
AL954322.2
ENSDARG00000097072
KN149808v1_+_14146 0.14

chr4_-_2209924 0.14 ENSDART00000082289
cpsf6
cleavage and polyadenylation specific factor 6
chr2_+_25107108 0.14 ENSDART00000136072
ifi30
interferon, gamma-inducible protein 30
chr12_-_13690508 0.14 ENSDART00000078021
foxh1
forkhead box H1
chr17_+_9918253 0.14 ENSDART00000169892
srp54
signal recognition particle 54
chr6_-_53333532 0.14 ENSDART00000172465
gnb1b
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr3_+_35277555 0.13

chr3_+_48362748 0.13 ENSDART00000157199
mkl2b
MKL/myocardin-like 2b
chr16_+_33041823 0.13 ENSDART00000170157
prss35
protease, serine, 35
chr1_+_11448327 0.13 ENSDART00000126020
spink4
serine peptidase inhibitor, Kazal type 4
chr16_+_26892979 0.13 ENSDART00000048036
gem
GTP binding protein overexpressed in skeletal muscle
chr23_-_36319185 0.13 ENSDART00000139328
znf740b
zinc finger protein 740b
chr19_+_20194594 0.13 ENSDART00000169074
hoxa4a
homeobox A4a
KN150437v1_-_892 0.13 ENSDART00000178017
ENSDART00000175804
CABZ01103416.1
ENSDARG00000106284
chr21_+_22808694 0.12 ENSDART00000065555
birc2
baculoviral IAP repeat containing 2
chr13_+_3533517 0.12 ENSDART00000018737
qkib
QKI, KH domain containing, RNA binding b
chr17_+_38314814 0.12 ENSDART00000017493
nkx2.1
NK2 homeobox 1
chr3_+_59608335 0.12 ENSDART00000064311
arhgdia
Rho GDP dissociation inhibitor (GDI) alpha
chr12_-_36145252 0.12

chr7_+_19583578 0.12 ENSDART00000149812
ovol1
ovo-like zinc finger 1
chr16_+_10666906 0.12 ENSDART00000091241
si:ch73-22o12.1
si:ch73-22o12.1
chr8_+_5222065 0.12 ENSDART00000035676
bnip3la
BCL2/adenovirus E1B interacting protein 3-like a
chr11_+_18710724 0.12 ENSDART00000176141
magi1b
membrane associated guanylate kinase, WW and PDZ domain containing 1b
chr11_-_32461160 0.12 ENSDART00000155592
pcdh17
protocadherin 17
chr14_+_35906366 0.11 ENSDART00000105602
elovl6
ELOVL fatty acid elongase 6
chr23_+_31888903 0.11 ENSDART00000075730
myb
v-myb avian myeloblastosis viral oncogene homolog
chr7_+_22314304 0.11 ENSDART00000149144
chrnb1l
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr19_+_43524098 0.11 ENSDART00000129362
eef1a1l2
eukaryotic translation elongation factor 1 alpha 1, like 2
chr10_+_37033 0.11 ENSDART00000157786
riox2
ribosomal oxygenase 2
chr4_+_8007802 0.11 ENSDART00000014036
optn
optineurin
chr2_+_3202934 0.11 ENSDART00000020463
zgc:63882
zgc:63882
chr4_+_45204456 0.11 ENSDART00000158744
BX927336.3
ENSDARG00000102848
chr23_+_17428538 0.11

chr7_-_667670 0.11 ENSDART00000159359
rela
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr16_-_11908084 0.11 ENSDART00000135408
cnfn
cornifelin
chr16_+_29696109 0.10 ENSDART00000153683
VPS72
vacuolar protein sorting 72 homolog
chr13_+_36831946 0.10 ENSDART00000024386
frmd6
FERM domain containing 6
chr12_+_26971596 0.10

chr4_-_12915292 0.10 ENSDART00000067135
msrb3
methionine sulfoxide reductase B3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:1904035 epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.3 0.8 GO:0019731 antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.2 0.8 GO:0071869 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.2 0.6 GO:0046552 retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220) distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
0.2 0.5 GO:0035523 protein K29-linked deubiquitination(GO:0035523) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.1 0.7 GO:0090104 pancreatic epsilon cell differentiation(GO:0090104)
0.1 0.4 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.1 0.8 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.1 0.4 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 0.4 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.1 0.5 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 1.2 GO:0035462 determination of left/right asymmetry in diencephalon(GO:0035462) determination of left/right asymmetry in nervous system(GO:0035545)
0.1 0.3 GO:0060760 positive regulation of cytokine-mediated signaling pathway(GO:0001961) positive regulation of response to cytokine stimulus(GO:0060760)
0.1 0.3 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.1 0.3 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.1 0.5 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.8 GO:0021684 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.2 GO:0051101 regulation of DNA binding(GO:0051101)
0.1 0.2 GO:0014005 microglia development(GO:0014005)
0.1 0.4 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.1 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.1 0.1 GO:0030852 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.1 0.3 GO:0045144 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.2 GO:0035777 pronephric distal tubule development(GO:0035777)
0.0 0.1 GO:0046833 regulation of nucleobase-containing compound transport(GO:0032239) positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of nucleocytoplasmic transport(GO:0046824) regulation of RNA export from nucleus(GO:0046831) positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.2 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.4 GO:0021703 locus ceruleus development(GO:0021703)
0.0 0.7 GO:1903707 negative regulation of hemopoiesis(GO:1903707)
0.0 0.2 GO:0010159 specification of organ position(GO:0010159)
0.0 0.2 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.0 0.5 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 1.2 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.2 GO:0010525 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.0 0.6 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.7 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.2 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.0 0.4 GO:0015671 oxygen transport(GO:0015671)
0.0 0.2 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.0 0.1 GO:1901842 regulation of high voltage-gated calcium channel activity(GO:1901841) negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.0 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.0 0.2 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.5 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.3 GO:1902622 regulation of neutrophil migration(GO:1902622)
0.0 0.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.0 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.1 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.6 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.0 0.2 GO:0033292 T-tubule organization(GO:0033292)
0.0 0.2 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.2 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.8 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.5 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.2 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.0 0.4 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.1 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.3 GO:0042149 cellular response to glucose starvation(GO:0042149)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.4 GO:0071159 NF-kappaB complex(GO:0071159)
0.1 0.4 GO:0005833 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.3 GO:0000780 condensed nuclear chromosome kinetochore(GO:0000778) condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 0.1 GO:0016234 inclusion body(GO:0016234)
0.0 0.1 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.8 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.1 GO:0030062 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947) mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.0 GO:0030314 junctional membrane complex(GO:0030314)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.7 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 1.0 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 0.8 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.6 GO:0017046 peptide hormone binding(GO:0017046)
0.1 0.4 GO:0031720 haptoglobin binding(GO:0031720)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.0 0.3 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.1 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 1.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 1.2 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.1 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.2 GO:0097200 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0019201 nucleotide kinase activity(GO:0019201)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.0 GO:0030623 U5 snRNA binding(GO:0030623)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.9 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA