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Results for relb

Z-value: 0.66

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Transcription factors associated with relb

Gene Symbol Gene ID Gene Info
ENSDARG00000086173 v-rel avian reticuloendotheliosis viral oncogene homolog B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
relbdr10_dc_chr15_+_17164373_171644290.234.0e-01Click!

Activity profile of relb motif

Sorted Z-values of relb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of relb

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_-_37418967 1.57 ENSDART00000015723
protein kinase C, iota
chr11_+_34788205 1.23 ENSDART00000124800
family with sequence similarity 212, member Aa
chr3_-_39316317 1.17

chr8_+_39762186 1.14 ENSDART00000143413
si:ch211-170d8.2
chr2_+_21698100 1.09 ENSDART00000145670
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b
chr3_-_22240424 1.07

chr7_+_40878834 0.98

chr16_+_35582277 0.83 ENSDART00000167001
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr7_-_37283707 0.81 ENSDART00000148905
ENSDART00000150229
cylindromatosis (turban tumor syndrome), a
chr6_-_10492123 0.76 ENSDART00000002247
Sp3b transcription factor
chr1_-_30299017 0.66

chr10_-_1933874 0.64 ENSDART00000101023
teratocarcinoma-derived growth factor 1
chr16_-_55211053 0.61 ENSDART00000156533
keratinocyte differentiation factor 1a
chr6_-_10492276 0.60 ENSDART00000002247
Sp3b transcription factor
chr2_-_37419017 0.58 ENSDART00000015723
protein kinase C, iota
chr21_+_15660479 0.56 ENSDART00000101956
ENSDART00000026903
protein tyrosine phosphatase, receptor type, A
chr5_+_58564789 0.53 ENSDART00000045518
PRKR interacting protein 1 (IL11 inducible)
chr8_-_1669966 0.52

chr13_+_36832090 0.49 ENSDART00000024386
FERM domain containing 6
chr23_-_33811895 0.49 ENSDART00000131680
si:ch211-210c8.7
chr19_-_7151715 0.47 ENSDART00000168755
TAP binding protein (tapasin), tandem duplicate 2
chr1_-_54585975 0.47 ENSDART00000152504
si:ch211-286b5.4
chr5_+_58564645 0.47 ENSDART00000045518
PRKR interacting protein 1 (IL11 inducible)
chr23_-_18671263 0.46 ENSDART00000008847
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr15_+_6462447 0.46 ENSDART00000065824
beta-site APP-cleaving enzyme 2
chr19_+_46667326 0.43 ENSDART00000158032
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1a (glutamate binding)
chr10_-_1933761 0.42 ENSDART00000101023
teratocarcinoma-derived growth factor 1
chr2_-_30216377 0.42 ENSDART00000130142
ubiquitin-conjugating enzyme E2W (putative)
chr3_-_9755642 0.42 ENSDART00000168366
CREB binding protein b
chr5_-_11074111 0.41

chr25_-_6263768 0.40 ENSDART00000166084
SIN3 transcription regulator family member Aa
chr22_+_21996941 0.39 ENSDART00000149586
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1
chr8_-_50899562 0.38 ENSDART00000053750
acyl-CoA synthetase long-chain family member 2
chr3_-_3646681 0.38 ENSDART00000165648
ENSDART00000046454
ENSDART00000115282
ENSDART00000164463
ENSDARG00000076771
chr4_-_12782246 0.37 ENSDART00000058020
helicase (DNA) B
chr13_-_4863766 0.37 ENSDART00000159679
nucleolar and coiled-body phosphoprotein 1
chr25_+_15901398 0.36 ENSDART00000140047
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr16_+_35582411 0.36 ENSDART00000171675
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr3_+_17728616 0.36 ENSDART00000167953
DnaJ (Hsp40) homolog, subfamily C, member 7
chr23_+_17428538 0.35

chr20_+_16982314 0.35 ENSDART00000146625
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a
chr2_-_37555425 0.35 ENSDART00000143496
rho/rac guanine nucleotide exchange factor (GEF) 18a
chr5_+_57050210 0.34

chr5_+_23582676 0.33 ENSDART00000139520
tumor protein p53
chr1_+_54059634 0.32 ENSDART00000162075
phosphatidylinositol 4-kinase type 2 alpha
chr22_+_1445227 0.31 ENSDART00000164685
si:dkeyp-53d3.5
chr16_-_24916921 0.31 ENSDART00000153731
si:dkey-79d12.5
chr11_+_36093297 0.30 ENSDART00000077649
synaptophysin-like 2a
chr21_+_21242470 0.30 ENSDART00000148346
inositol-trisphosphate 3-kinase Ca
chr13_+_22586873 0.29 ENSDART00000134122
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr5_-_67395562 0.29 ENSDART00000165052
ENSDART00000018792
sperm associated antigen 7
chr2_+_21516908 0.28 ENSDART00000079518
DnaJ (Hsp40) homolog, subfamily C, member 1
chr21_+_19381959 0.27 ENSDART00000080110
alpha-methylacyl-CoA racemase
chr5_+_23582805 0.27 ENSDART00000137298
tumor protein p53
chr7_+_6629933 0.26

chr3_-_39316355 0.26

chr13_-_46424420 0.25

chr24_+_5863770 0.25 ENSDART00000161104
microtubule associated serine/threonine kinase-like
chr23_-_18671336 0.25 ENSDART00000008847
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr22_-_2828572 0.24

chr13_+_15685745 0.24 ENSDART00000137061
kinesin light chain 1a
chr6_-_10492439 0.23 ENSDART00000002247
Sp3b transcription factor
chr17_+_12788541 0.23 ENSDART00000016597
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b
chr24_-_21788942 0.22 ENSDART00000113092
abhydrolase domain containing 10b
chr11_-_42934175 0.22 ENSDART00000172929
spectrin, beta, non-erythrocytic 1
chr22_-_10410949 0.22 ENSDART00000111962
ENSDART00000064809
nucleolar protein 8
chr2_-_30216703 0.22 ENSDART00000130142
ubiquitin-conjugating enzyme E2W (putative)
chr15_+_38113499 0.21

chr5_+_23582396 0.20 ENSDART00000051549
ENSDART00000135934
tumor protein p53
chr7_+_13130367 0.20 ENSDART00000166318
diacylglycerol lipase, alpha
chr7_-_50546498 0.20

chr2_-_32755182 0.19 ENSDART00000041146
nuclear receptor binding protein 2a
chr20_-_5008341 0.19

chr15_+_17164373 0.18 ENSDART00000123197
ENSDART00000154418
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr23_+_3570243 0.18 ENSDART00000092258
spermatogenesis associated 2
chr25_-_34634739 0.18 ENSDART00000157370
Histone H3.2
chr13_+_36831946 0.18 ENSDART00000024386
FERM domain containing 6
chr9_-_9264634 0.17 ENSDART00000021191
U2 small nuclear RNA auxiliary factor 1
chr21_+_13689239 0.17 ENSDART00000112451
solute carrier family 31 (copper transporter), member 2
chr25_-_10532989 0.16 ENSDART00000177834
protein phosphatase 6, regulatory subunit 3
chr11_+_40280114 0.16 ENSDART00000175424
membrane metallo-endopeptidase-like 1
chr25_-_6263829 0.16 ENSDART00000166084
SIN3 transcription regulator family member Aa
chr12_+_23939657 0.16 ENSDART00000021298
ankyrin repeat and SOCS box containing 3
chr13_-_34667689 0.16 ENSDART00000025719
isthmin 1
chr15_+_38113014 0.15

chr3_-_31487744 0.15 ENSDART00000124559
minamoto
chr5_+_6391432 0.15 ENSDART00000170564
ENSDART00000086666
sperm-tail PG-rich repeat containing 2
chr10_+_42714071 0.15 ENSDART00000005496
potassium channel tetramerization domain containing 9b
chr15_-_23594718 0.14 ENSDART00000152543
hydroxymethylbilane synthase, b
chr25_+_34546629 0.14 ENSDART00000133379
histone cluster 2, H3c
chr25_+_15901561 0.14 ENSDART00000140047
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr6_+_3174047 0.14 ENSDART00000160290
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr13_+_22589282 0.14 ENSDART00000057672
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr2_-_30216240 0.13 ENSDART00000130142
ubiquitin-conjugating enzyme E2W (putative)
chr16_-_32174276 0.13 ENSDART00000137699
CCR4-NOT transcription complex, subunit 3a
chr20_-_21775455 0.13

chr18_-_16934961 0.13 ENSDART00000122102
WEE1 G2 checkpoint kinase
chr15_+_6462607 0.13 ENSDART00000065824
beta-site APP-cleaving enzyme 2
chr5_+_24378828 0.13 ENSDART00000111302
rhomboid domain containing 3
chr24_-_11365575 0.12 ENSDART00000140217
pre-mRNA processing factor 4Bb
chr15_-_37202518 0.12 ENSDART00000165867
zmp:0000001114
chr2_-_30216333 0.12 ENSDART00000130142
ubiquitin-conjugating enzyme E2W (putative)
chr8_-_17755104 0.12 ENSDART00000131276
si:ch211-150o23.2
chr5_-_43219303 0.12 ENSDART00000022481
methylcrotonoyl-CoA carboxylase 2 (beta)
chr5_-_28522443 0.12 ENSDART00000144802
deafness, autosomal recessive 31b
chr21_+_19511167 0.11 ENSDART00000058487
retinoic acid induced 14
chr15_+_17164535 0.11 ENSDART00000155350
v-rel avian reticuloendotheliosis viral oncogene homolog B
chr21_+_21754830 0.10 ENSDART00000151654
sialidase 3 (membrane sialidase), tandem duplicate 1
chr2_+_8981028 0.10 ENSDART00000134308
zinc finger, ZZ-type containing 3
chr9_-_11291927 0.10 ENSDART00000113847
chondroitin polymerizing factor a
chr20_+_31375056 0.10

chr9_+_42805317 0.10 ENSDART00000138133
GULP, engulfment adaptor PTB domain containing 1a
chr7_+_40879017 0.10

chr1_-_22603603 0.08 ENSDART00000013263
UDP-glucose 6-dehydrogenase
chr20_+_31375136 0.08

chr15_-_38113404 0.08

chr9_+_492726 0.08 ENSDART00000112635
ENSDARG00000078172
chr19_-_17039269 0.07

chr25_+_34557335 0.07 ENSDART00000089844
zgc:113983
chr7_+_13130332 0.07 ENSDART00000166318
diacylglycerol lipase, alpha
chr7_-_37283894 0.06 ENSDART00000148905
ENSDART00000150229
cylindromatosis (turban tumor syndrome), a
chr12_-_28732946 0.04 ENSDART00000153200
si:ch211-194k22.8
chr19_-_307085 0.04 ENSDART00000145916
leucine rich repeat and Ig domain containing 4a
chr5_-_52318158 0.04 ENSDART00000166267
zinc finger protein-like 1
chr3_+_35276575 0.04 ENSDART00000102994
retinoblastoma binding protein 6
chr1_+_28407560 0.04 ENSDART00000053924
insulin receptor substrate 2a
chr20_+_23602537 0.03

chr25_+_15901662 0.03 ENSDART00000140047
PTPRF interacting protein, binding protein 2b (liprin beta 2)
chr8_-_12394879 0.03 ENSDART00000101174
TNF receptor-associated factor 1
chr17_-_28794581 0.03 ENSDART00000132811
G2/M-phase specific E3 ubiquitin protein ligase
chr17_+_51593393 0.03 ENSDART00000004379
nucleolar protein 10
chr13_+_36832145 0.02 ENSDART00000024386
FERM domain containing 6
chr14_-_6096258 0.02

chr20_-_6153384 0.02 ENSDART00000161566
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
chr22_-_37092134 0.02

chr6_-_48474815 0.01 ENSDART00000154237
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr23_-_36349563 0.00

chr13_-_22964527 0.00 ENSDART00000089242
kif1 binding protein

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.4 1.1 GO:0072045 convergent extension involved in nephron morphogenesis(GO:0072045)
0.2 0.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.2 0.6 GO:0010481 keratinocyte development(GO:0003334) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.8 GO:0010525 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.1 0.9 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 0.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.6 GO:0050435 beta-amyloid metabolic process(GO:0050435) melanocyte migration(GO:0097324)
0.1 0.3 GO:0098920 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) retrograde trans-synaptic signaling by lipid(GO:0098920) retrograde trans-synaptic signaling by endocannabinoid(GO:0098921) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.4 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.0 0.2 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.4 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.1 GO:0010939 regulation of tumor necrosis factor-mediated signaling pathway(GO:0010803) regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.0 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0007141 male meiosis I(GO:0007141)
0.0 0.3 GO:0007032 endosome organization(GO:0007032)
0.0 0.1 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.1 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.3 GO:1903707 negative regulation of hemopoiesis(GO:1903707)
0.0 0.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.1 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 1.0 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 0.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.3 GO:0038061 NIK/NF-kappaB signaling(GO:0038061)
0.0 0.1 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0005915 cell-cell adherens junction(GO:0005913) zonula adherens(GO:0005915)
0.1 0.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:1905202 methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.3 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.5 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.1 1.1 GO:0070697 activin receptor binding(GO:0070697)
0.1 0.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 1.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.3 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.1 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
0.0 0.3 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.6 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.0 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.0 0.2 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.4 GO:0043142 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 0.1 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.3 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.6 GO:0003713 transcription coactivator activity(GO:0003713)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.1 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.7 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 1.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint