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Results for roraa+rorab

Z-value: 0.39

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Transcription factors associated with roraa+rorab

Gene Symbol Gene ID Gene Info
ENSDARG00000001910 RAR-related orphan receptor A, paralog b
ENSDARG00000031768 RAR-related orphan receptor A, paralog a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rorabdr10_dc_chr7_-_29354323_293543840.448.8e-02Click!
roraadr10_dc_chr25_+_33364224_333643020.381.5e-01Click!

Activity profile of roraa+rorab motif

Sorted Z-values of roraa+rorab motif

Network of associatons between targets according to the STRING database.

First level regulatory network of roraa+rorab

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_-_22881453 0.52

chr25_-_30818836 0.50 ENSDART00000156828
proline rich 33
chr6_-_39767452 0.48 ENSDART00000085277
phosphofructokinase, muscle b
chr21_+_7844259 0.45 ENSDART00000027268
orthopedia homeobox a
chr13_+_50062513 0.42 ENSDART00000124142
ENSDART00000099537
cytochrome c oxidase subunit Vb 2
chr9_-_53220424 0.41

chr11_+_30482530 0.39 ENSDART00000103270
solute carrier family 22 (organic anion transporter), member 7a
chr23_+_20183765 0.38 ENSDART00000054664
troponin C type 1b (slow)
chr15_-_12338925 0.36 ENSDART00000170093
si:dkey-36i7.3
chr21_-_19789339 0.35

chr2_+_42342148 0.35 ENSDART00000144716
caveolae associated protein 4a
chr1_-_50215233 0.34 ENSDART00000137648
si:dkeyp-123h10.2
chr20_+_40247918 0.34 ENSDART00000121818
triadin
chr7_-_3900148 0.32 ENSDART00000019949
NDRG family member 2
chr13_-_21557620 0.31 ENSDART00000063825
shadow of prion protein
chr18_+_36650892 0.31 ENSDART00000098980
zinc finger protein 296
chr16_-_28921444 0.31 ENSDART00000078543
synaptotagmin XIb
chr5_-_29818204 0.30 ENSDART00000098285
activating transcription factor 5a
chr14_-_33114284 0.30 ENSDART00000109615
transmembrane protein 255A
chr12_+_30673985 0.29 ENSDART00000160422
aldehyde dehydrogenase 18 family, member A1
chr12_-_43939028 0.28 ENSDART00000170723
zgc:112964
chr20_-_39002962 0.28

chr1_+_30840735 0.28 ENSDART00000075286
solute carrier family 2 (facilitated glucose transporter), member 15b
chr19_+_20392669 0.27 ENSDART00000052627
neuropeptide VF precursor
chr3_-_16056593 0.27

chr19_-_5186692 0.27 ENSDART00000037007
triosephosphate isomerase 1a
chr22_-_10324166 0.27 ENSDART00000092050
stabilin 1
chr10_+_37983342 0.27 ENSDART00000172548
basic helix-loop-helix family, member a9
chr24_-_5995073 0.25 ENSDART00000040865
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr9_-_21257082 0.24 ENSDART00000124533
T-box 15
chr14_-_33114322 0.24 ENSDART00000173267
transmembrane protein 255A
chr7_+_39957385 0.24 ENSDART00000052222
protein tyrosine phosphatase, receptor type, N polypeptide 2
chr24_-_21768269 0.24 ENSDART00000081178
C1q and TNF related 9
chr4_+_14658179 0.23 ENSDART00000168152
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr11_+_24874769 0.23 ENSDART00000147546
ndrg family member 3a
chr10_+_20156511 0.22 ENSDART00000139722
dematin actin binding protein
chr6_-_10086031 0.22

chr4_-_17640519 0.21 ENSDART00000108814
nuclear receptor interacting protein 2
chr20_-_14784875 0.21 ENSDART00000063857
secernin 2
chr14_-_30150071 0.21 ENSDART00000173107
mitochondrial calcium uptake family, member 3b
chr1_+_30840656 0.21 ENSDART00000075286
solute carrier family 2 (facilitated glucose transporter), member 15b
chr11_+_39768864 0.21 ENSDART00000130278
si:dkey-264d12.1
chr8_+_6533379 0.21 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr7_-_29070193 0.21 ENSDART00000147251
transient receptor potential cation channel, subfamily M, member 1a
chr7_-_3900223 0.20 ENSDART00000019949
NDRG family member 2
chr11_+_39768718 0.19 ENSDART00000130278
si:dkey-264d12.1
chr19_+_38033219 0.19 ENSDART00000158960
thrombospondin, type I, domain containing 7Aa
chr21_+_5775383 0.19 ENSDART00000165065
ubiquinol-cytochrome c reductase, complex III subunit X
chr17_+_33388313 0.19 ENSDART00000077553
xanthine dehydrogenase
chr18_-_48498261 0.18 ENSDART00000146346
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr24_+_29902165 0.17 ENSDART00000168422
ENSDART00000100092
ENSDART00000113304
ferric-chelate reductase 1b
chr13_+_42276937 0.16

chr18_-_11439124 0.16

chr4_-_1346961 0.16 ENSDART00000164623
pleiotrophin
chr18_-_15641443 0.16 ENSDART00000127614
aryl hydrocarbon receptor nuclear translocator-like 2
chr1_-_44476084 0.15 ENSDART00000034549
zgc:111983
chr7_+_51499409 0.15 ENSDART00000007767
glutamic-oxaloacetic transaminase 2b, mitochondrial
chr6_-_15444945 0.14

chr7_+_30698873 0.14 ENSDART00000155974
tight junction protein 1a
chr17_-_7661762 0.14 ENSDART00000135538
required for meiotic nuclear division 1 homolog
chr10_+_4924008 0.14 ENSDART00000108595
solute carrier family 46 member 2
chr14_-_29518685 0.13 ENSDART00000136380
sorbin and SH3 domain containing 2b
chr22_+_18521411 0.13

chr18_+_17564926 0.13

chr6_-_39767422 0.13 ENSDART00000085277
phosphofructokinase, muscle b
chr11_+_30482504 0.12 ENSDART00000103270
solute carrier family 22 (organic anion transporter), member 7a
chr3_+_13487523 0.12 ENSDART00000166000
si:ch211-194b1.1
chr22_+_29694605 0.12

chr25_-_21058459 0.11 ENSDART00000156257
WNK lysine deficient protein kinase 1a
chr7_+_28862183 0.11 ENSDART00000052346
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr7_-_23775835 0.11 ENSDART00000144616
dehydrogenase/reductase (SDR family) member 4
chr3_+_44928592 0.11 ENSDART00000168864
zgc:112146
chr3_-_26060748 0.11 ENSDART00000144726
yippee-like 3
chr12_-_24711169 0.11 ENSDART00000066317
forkhead box N2b
chr19_+_21140010 0.11 ENSDART00000090757
K(lysine) acetyltransferase 2B
chr11_+_24662538 0.11 ENSDART00000148023
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr17_+_30431520 0.10 ENSDART00000153826
lipin 1
chr16_-_30775394 0.10

chr18_-_12483329 0.10 ENSDART00000092522
si:ch211-1e14.1
chr10_+_4924065 0.10 ENSDART00000108595
solute carrier family 46 member 2
chr2_-_14757989 0.10 ENSDART00000162816
ENSDARG00000099630
chr3_+_1413640 0.10 ENSDART00000055430
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6
chr14_-_4166292 0.09 ENSDART00000127318
FERM and PDZ domain containing 1b
chr7_-_33080261 0.09 ENSDART00000114041
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr7_-_29300402 0.09 ENSDART00000099477
RAR-related orphan receptor A, paralog b
chr18_-_11439216 0.09

chr23_-_24562107 0.09 ENSDART00000155593
transmembrane protein 82
chr24_+_37839153 0.09

chr23_+_42920817 0.09 ENSDART00000055577
myosin, light chain 9a, regulatory
chr15_+_5124690 0.09 ENSDART00000101937
phosphoglucomutase 2-like 1
chr6_-_42951571 0.09 ENSDART00000003298
ER degradation enhancer, mannosidase alpha-like 1
chr18_+_45574464 0.09

chr19_+_44073707 0.09 ENSDART00000051723
si:ch211-193k19.1
chr6_+_9801649 0.08 ENSDART00000149537
succinate-CoA ligase, ADP-forming, beta subunit
chr13_+_15669924 0.08 ENSDART00000146234
apoptogenic 1, mitochondrial
chr20_+_45531190 0.08

chr8_+_48888672 0.08

chr17_-_7661725 0.08 ENSDART00000143870
required for meiotic nuclear division 1 homolog
chr6_-_45993454 0.07 ENSDART00000154392
carbonic anhydrase XVI b
chr17_-_45140696 0.07

chr11_+_31346560 0.07 ENSDART00000124830
ENSDART00000162768
zgc:162816
chr7_-_50546498 0.07

chr6_+_40525779 0.07 ENSDART00000033819
protein kinase C, delta a
chr1_+_23093114 0.07

chr7_+_48532096 0.07

chr18_+_29984261 0.07

chr5_-_68751287 0.07 ENSDART00000112692
ENSDARG00000077155
chr7_+_22521055 0.07 ENSDART00000146801
RNA binding motif protein 4.3
chr1_+_58608231 0.07 ENSDART00000161872
ENSDART00000160658
poly(A)-specific ribonuclease (deadenylation nuclease)
chr6_-_40314512 0.07 ENSDART00000033844
collagen, type VII, alpha 1
chr14_+_23220869 0.07 ENSDART00000112930
si:ch211-221f10.2
chr5_-_54773058 0.06 ENSDART00000145791
prune homolog 2 (Drosophila)
chr14_-_14353451 0.06 ENSDART00000170355
ENSDART00000159888
NAD(P) dependent steroid dehydrogenase-like
chr1_+_46640008 0.06 ENSDART00000053284
B-cell CLL/lymphoma 9
chr8_-_7547623 0.06 ENSDART00000178825
host cell factor C1b
chr11_+_24662673 0.06 ENSDART00000148023
translocase of inner mitochondrial membrane 17 homolog A (yeast)
chr1_+_16834347 0.06 ENSDART00000005593
ENSDART00000140076
caspase 3, apoptosis-related cysteine peptidase a
chr14_-_4117151 0.06

chr7_-_29956782 0.06 ENSDART00000173514
zinc finger protein 710b
chr8_+_7974156 0.06

chr7_-_55879342 0.06 ENSDART00000098438
spastic paraplegia 7
chr14_+_33542705 0.06 ENSDART00000019396
chloride intracellular channel 2
chr7_-_48532099 0.05 ENSDART00000015884
milk fat globule-EGF factor 8 protein a
chr21_+_37668284 0.05 ENSDART00000131188
nuclear receptor binding SET domain protein 1b
chr7_-_55879197 0.05 ENSDART00000098438
spastic paraplegia 7
chr6_-_1562203 0.05 ENSDART00000067586
coiled-coil-helix-coiled-coil-helix domain containing 6b
chr6_-_10600358 0.05 ENSDART00000135065
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c3 (subunit 9) b
chr7_-_48532462 0.05 ENSDART00000015884
milk fat globule-EGF factor 8 protein a
chr7_+_26730804 0.05

chr22_+_39067994 0.05

chr20_-_53123015 0.05 ENSDART00000162812
farnesyl-diphosphate farnesyltransferase 1
chr25_-_21058792 0.05 ENSDART00000156257
WNK lysine deficient protein kinase 1a
chr3_-_26060787 0.05 ENSDART00000113843
yippee-like 3
chr14_-_15776937 0.05 ENSDART00000165656
MAX dimerization protein 3
chr18_-_15641870 0.04 ENSDART00000127614
aryl hydrocarbon receptor nuclear translocator-like 2
chr19_-_5416317 0.04 ENSDART00000010373
keratin, type 1, gene 19d
chr7_+_13238684 0.04 ENSDART00000053535
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 like
chr6_-_42951769 0.04 ENSDART00000147208
ER degradation enhancer, mannosidase alpha-like 1
chr7_+_48532543 0.04 ENSDART00000145375
carnitine palmitoyltransferase 1Aa (liver)
chr23_+_41935781 0.03 ENSDART00000171885
sterol carrier protein 2b
chr10_-_4924455 0.03

chr6_-_52484566 0.03 ENSDART00000112146
family with sequence similarity 83, member C
chr7_+_39812659 0.03 ENSDART00000099046
ENSDARG00000036489
chr2_-_45118469 0.03 ENSDART00000018818
mitochondrial E3 ubiquitin protein ligase 1a
chr18_+_9413668 0.03 ENSDART00000061886
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr6_-_39655998 0.03 ENSDART00000155859
La ribonucleoprotein domain family, member 4Ab
chr22_-_4867420 0.03 ENSDART00000132942
nicalin
chr4_-_3340275 0.03 ENSDART00000009076
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr2_+_10858655 0.03 ENSDART00000091570
family with sequence similarity 69, member Aa
chr24_-_8637129 0.02 ENSDART00000082362
male germ cell-associated kinase
chr3_+_44928323 0.02 ENSDART00000170913
zgc:112146
chr8_+_21192955 0.02 ENSDART00000129210
cryptochrome circadian clock 1ba
chr4_-_9780352 0.02 ENSDART00000080744
SVOP-like
chr13_-_36719000 0.02 ENSDART00000129562
ENSDART00000150899
ninein (GSK3B interacting protein)
chr12_-_24711074 0.02 ENSDART00000066317
forkhead box N2b
chr12_+_18407435 0.02 ENSDART00000146260
methionine sulfoxide reductase B1b
chr12_+_23742199 0.02

chr8_-_49227232 0.02

chr3_-_26060702 0.02 ENSDART00000144726
yippee-like 3
chr4_-_9779763 0.02 ENSDART00000134280
SVOP-like
chr9_-_30997261 0.02 ENSDART00000146300
Kruppel-like factor 5b
chr13_-_22776819 0.01 ENSDART00000143097
RUN and FYVE domain containing 2
chr11_+_25063488 0.01

chr13_-_37002066 0.01 ENSDART00000135510
spectrin repeat containing, nuclear envelope 2b
chr1_+_58608185 0.01 ENSDART00000161872
ENSDART00000160658
poly(A)-specific ribonuclease (deadenylation nuclease)
chr2_-_5811839 0.01 ENSDART00000100924
CWC25 spliceosome-associated protein homolog (S. cerevisiae)
chr2_-_14758209 0.01 ENSDART00000162816
ENSDARG00000099630
chr5_-_34856057 0.01 ENSDART00000051312
tetratricopeptide repeat domain 33
chr7_+_39812522 0.01 ENSDART00000099046
ENSDARG00000036489
chr15_-_11798324 0.01

chr13_+_33578737 0.01 ENSDART00000161465
ENSDARG00000104106
chr18_+_9413588 0.01 ENSDART00000061886
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr15_+_5124897 0.01 ENSDART00000101937
phosphoglucomutase 2-like 1
chr21_+_15613081 0.01 ENSDART00000065772
D-dopachrome tautomerase
chr18_-_20605032 0.01 ENSDART00000134722
BCL2-like 13 (apoptosis facilitator)
chr21_-_17001108 0.00 ENSDART00000101263
ubiquitin-conjugating enzyme E2G 1b (UBC7 homolog, yeast)
chr7_+_48532749 0.00 ENSDART00000145375
carnitine palmitoyltransferase 1Aa (liver)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0050886 sleep(GO:0030431) endocrine process(GO:0050886)
0.1 0.3 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.6 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.3 GO:1901492 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.3 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.1 0.2 GO:0006531 aspartate metabolic process(GO:0006531)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.4 GO:0021767 mammillary body development(GO:0021767)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.1 GO:1903010 regulation of bone development(GO:1903010)
0.0 0.2 GO:0010765 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0071236 cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.3 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.2 GO:0046113 nucleobase catabolic process(GO:0046113)
0.0 0.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.3 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.1 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.0 0.2 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.3 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.4 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.3 GO:0008929 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.1 0.6 GO:0070095 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.1 0.2 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.2 GO:0030151 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725) molybdenum ion binding(GO:0030151)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.2 GO:0017081 chloride channel regulator activity(GO:0017081) chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.0 0.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.2 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.2 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.1 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0004309 exopolyphosphatase activity(GO:0004309)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE