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Results for rreb1a+rreb1b

Z-value: 1.03

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Transcription factors associated with rreb1a+rreb1b

Gene Symbol Gene ID Gene Info
rreb1b
ENSDARG00000042652 ras responsive element binding protein 1b
rreb1a
ENSDARG00000063701 ras responsive element binding protein 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
rreb1bdr10_dc_chr2_+_21342233_213423980.741.1e-03Click!
rreb1adr10_dc_chr24_-_2453890_2453929-0.712.2e-03Click!

Activity profile of rreb1a+rreb1b motif

Sorted Z-values of rreb1a+rreb1b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of rreb1a+rreb1b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr8_+_54171992 3.11 ENSDART00000122692
CABZ01112317.1
ENSDARG00000086057
chr22_+_37944019 2.78

chr13_-_508202 2.59 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)
chr19_-_5441932 2.40 ENSDART00000105034
cyt1l
type I cytokeratin, enveloping layer, like
KN150170v1_+_10738 2.36 ENSDART00000159076
HUS1
HUS1 checkpoint clamp component
chr23_-_9833729 2.35 ENSDART00000045126
lama5
laminin, alpha 5
chr1_-_4845236 2.26 ENSDART00000103755
ENSDART00000023692
fn1b
fibronectin 1b
chr13_-_508050 2.15 ENSDART00000066080
ENSDART00000128969
slit1a
slit homolog 1a (Drosophila)
chr12_+_42281025 2.11 ENSDART00000167324
ebf3a
early B-cell factor 3a
chr12_+_2642541 2.08 ENSDART00000093113
antxr1c
anthrax toxin receptor 1c
chr5_-_71229872 1.98

chr18_+_284399 1.89 ENSDART00000158040
larp6
La ribonucleoprotein domain family, member 6
chr21_+_28408329 1.85 ENSDART00000077871
pygma
phosphorylase, glycogen, muscle A
chr4_+_15870605 1.84 ENSDART00000178674
BX004864.1
ENSDARG00000107641
chr13_-_11404389 1.77 ENSDART00000018155
adss
adenylosuccinate synthase
chr6_-_22504772 1.73 ENSDART00000170039
sept9b
septin 9b
KN149816v1_-_3337 1.68

chr25_+_34270560 1.66 ENSDART00000146669
wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr11_+_44809527 1.65 ENSDART00000037819
ENSDART00000159886
tmc6b
transmembrane channel-like 6b
chr23_+_2101659 1.63

chr21_-_44013995 1.61 ENSDART00000028960
ndufa2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
chr21_-_43020159 1.51 ENSDART00000065097
dpysl3
dihydropyrimidinase-like 3
chr14_-_9216303 1.50 ENSDART00000054689
atoh8
atonal bHLH transcription factor 8
chr19_+_48499602 1.49

chr8_-_1904720 1.47 ENSDART00000081563
si:dkey-178e17.3
si:dkey-178e17.3
chr9_-_34146631 1.46 ENSDART00000177897
AL590134.2
ENSDARG00000107869
chr9_+_30483319 1.45 ENSDART00000148148
srpx
sushi-repeat containing protein, X-linked
chr9_+_21911860 1.44 ENSDART00000102021
sox1a
SRY (sex determining region Y)-box 1a
chr9_+_37136519 1.43 ENSDART00000135281
ENSDART00000113562
si:dkey-3d4.3
si:dkey-3d4.3
chr19_+_31046291 1.43 ENSDART00000052124
fam49al
family with sequence similarity 49, member A-like
chr16_-_55320569 1.41 ENSDART00000156368
ENSDARG00000069583
ENSDARG00000069583
chr2_-_44330405 1.40 ENSDART00000111246
cadm3
cell adhesion molecule 3
chr17_+_8166167 1.40 ENSDART00000169900
cdc42bpaa
CDC42 binding protein kinase alpha (DMPK-like) a
chr25_+_11317025 1.38

chr7_-_2230502 1.38 ENSDART00000173879
si:cabz01007794.1
si:cabz01007794.1
chr8_+_4311821 1.36 ENSDART00000015214
pptc7a
PTC7 protein phosphatase homolog a
chr19_-_5464238 1.36 ENSDART00000105806
cyt1
type I cytokeratin, enveloping layer
chr19_+_43414160 1.33 ENSDART00000033724
fabp3
fatty acid binding protein 3, muscle and heart
chr11_-_4216204 1.29 ENSDART00000121716
ENSDARG00000086300
ENSDARG00000086300
chr16_-_39181608 1.28 ENSDART00000075517
gdf6a
growth differentiation factor 6a
chr5_-_71340996 1.27 ENSDART00000162526
smyd1a
SET and MYND domain containing 1a
chr6_+_59788008 1.27

chr7_-_73530653 1.26 ENSDART00000166633
ENSDART00000009888
ENSDART00000171254
casq1b
calsequestrin 1b
KN150596v1_+_18342 1.21 ENSDART00000169155
ppic
peptidylprolyl isomerase C
chr10_+_22802607 1.20 ENSDART00000144845
tmem88a
transmembrane protein 88 a
chr11_-_25803101 1.18 ENSDART00000088888
kaznb
kazrin, periplakin interacting protein b
chr17_+_1610578 1.18 ENSDART00000082101
ppp2r5ca
protein phosphatase 2, regulatory subunit B', gamma a
chr25_-_36886647 1.15 ENSDART00000160688
psma1
proteasome subunit alpha 1
chr13_-_20387917 1.14 ENSDART00000167916
ENSDART00000165310
ENSDART00000168955
gfra1a
gdnf family receptor alpha 1a
chr7_-_12656353 1.13 ENSDART00000023301
ENSDART00000172901
ENSDART00000163045
ENSDART00000163461
sh3gl3a
SH3-domain GRB2-like 3a
chr4_-_16356071 1.12 ENSDART00000079521
kera
keratocan
chr25_+_5162045 1.12 ENSDART00000169540
ENSDARG00000101164
ENSDARG00000101164
chr7_+_31567166 1.12 ENSDART00000099785
ENSDART00000122506
mybpc3
myosin binding protein C, cardiac
chr3_+_16115708 1.10 ENSDART00000122519
st8sia6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr13_-_25067585 1.10 ENSDART00000159585
adka
adenosine kinase a
chr3_-_38550961 1.09 ENSDART00000155042
mpp3a
membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3)
chr14_+_34174018 1.09 ENSDART00000024440
foxi3b
forkhead box I3b
chr5_-_71643185 1.09 ENSDART00000029014
pax8
paired box 8
chr16_+_5470544 1.08

chr25_-_207828 1.08 ENSDART00000169152
srpk2
SRSF protein kinase 2
chr15_+_37204488 1.07 ENSDART00000157762
aplp1
amyloid beta (A4) precursor-like protein 1
chr13_-_31304614 1.07

chr6_-_53426323 1.01 ENSDART00000162791
mst1
macrophage stimulating 1
chr8_+_166461 1.00

chr15_-_40328793 0.99 ENSDART00000155018
si:ch211-281l24.3
si:ch211-281l24.3
chr23_+_45020761 0.99 ENSDART00000159104
atp1b2a
ATPase, Na+/K+ transporting, beta 2a polypeptide
chr11_+_23522743 0.98 ENSDART00000121874
nfasca
neurofascin homolog (chicken) a
chr25_+_57432 0.95 ENSDART00000128281
cntn1a
contactin 1a
chr3_+_59716594 0.95 ENSDART00000157351
ENSDART00000153928
si:ch211-110e21.3
si:ch211-110e21.3
chr16_+_22672315 0.94 ENSDART00000142241
she
Src homology 2 domain containing E
chr25_+_17366098 0.94

chr23_+_22350713 0.94 ENSDART00000130375
rap1gap
RAP1 GTPase activating protein
chr19_-_6856033 0.94 ENSDART00000170952
pvrl2l
poliovirus receptor-related 2 like
chr12_+_41016238 0.93 ENSDART00000170976
kif5bb
kinesin family member 5B, b
chr12_+_1370058 0.93 ENSDART00000026303
rasd1
RAS, dexamethasone-induced 1
chr6_+_59762717 0.93 ENSDART00000050457
zgc:65895
zgc:65895
chr14_-_46646747 0.92

chr17_-_20830398 0.92 ENSDART00000149630
ank3a
ankyrin 3a
chr21_-_45573799 0.90 ENSDART00000158489
zgc:77058
zgc:77058
chr25_+_5232865 0.90

chr18_+_284567 0.90 ENSDART00000158040
larp6
La ribonucleoprotein domain family, member 6
KN150039v1_-_936 0.89 ENSDART00000168136
HDGFL3
HDGF like 3
chr19_-_9192541 0.88

KN149973v1_+_28300 0.88

chr15_-_16271208 0.88

chr18_+_30391910 0.88 ENSDART00000158871
gse1
Gse1 coiled-coil protein
chr25_+_36878565 0.87 ENSDART00000157596
ric3b
RIC3 acetylcholine receptor chaperone b
chr5_-_1498277 0.87

chr17_+_53224434 0.87 ENSDART00000166517
asb2b
ankyrin repeat and SOCS box containing 2b
chr5_-_70915664 0.86

chr5_+_474163 0.86 ENSDART00000055681
tek
TEK tyrosine kinase, endothelial
chr10_+_24476213 0.85 ENSDART00000146370
slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr21_-_41445163 0.85 ENSDART00000170457
hmp19
HMP19 protein
chr12_+_13206107 0.85 ENSDART00000105896
atp2a1l
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 like
chr9_-_216905 0.84 ENSDART00000163068
aaas
achalasia, adrenocortical insufficiency, alacrimia
chr10_-_43466392 0.84 ENSDART00000062631
hapln1b
hyaluronan and proteoglycan link protein 1b
chr22_-_29577 0.82 ENSDART00000158058
NBL1
MINOS1-NBL1 readthrough
chr10_-_43466478 0.81 ENSDART00000062631
hapln1b
hyaluronan and proteoglycan link protein 1b
chr17_+_52736192 0.81 ENSDART00000158273
ENSDART00000161414
meis2a
Meis homeobox 2a
chr13_+_22545318 0.81 ENSDART00000143312
zgc:193505
zgc:193505
KN149968v1_+_15749 0.80 ENSDART00000168977
ENSDARG00000102503
ENSDARG00000102503
chr20_-_35343242 0.80 ENSDART00000113294
fzd3a
frizzled class receptor 3a
chr21_+_25729090 0.80 ENSDART00000021664
cldnb
claudin b
chr9_-_46272322 0.79 ENSDART00000169682
hdac4
histone deacetylase 4
chr2_+_23038657 0.78 ENSDART00000089012
kif1ab
kinesin family member 1Ab
chr24_+_26944182 0.77 ENSDART00000089541
dip2ca
disco-interacting protein 2 homolog Ca
KN149987v1_-_29629 0.77 ENSDART00000159555
ENSDART00000168161
ENSDARG00000103311
ENSDARG00000103311
chr9_+_22953351 0.76 ENSDART00000090875
tnfaip6
tumor necrosis factor, alpha-induced protein 6
chr14_-_46646451 0.76

chr20_-_10133201 0.75 ENSDART00000144970
meis2b
Meis homeobox 2b
chr7_+_16677929 0.73

chr25_+_33364224 0.73 ENSDART00000121449
roraa
RAR-related orphan receptor A, paralog a
chr8_+_388003 0.72 ENSDART00000067668
pym1
PYM homolog 1, exon junction complex associated factor
chr25_+_7660590 0.72 ENSDART00000155016
dgkzb
diacylglycerol kinase, zeta b
chr19_-_47897712 0.72

chr22_+_1169970 0.71 ENSDART00000171060
ENSDART00000167710
eps8l3a
EPS8-like 3a
chr22_-_95158 0.71

chr17_-_20830287 0.71 ENSDART00000149630
ank3a
ankyrin 3a
chr24_-_2373152 0.70

chr14_+_503643 0.70

chr10_-_38372282 0.68 ENSDART00000149580
nrip1b
nuclear receptor interacting protein 1b
chr10_-_45535333 0.68

chr17_-_5703094 0.66 ENSDART00000058894
si:ch73-340m8.2
si:ch73-340m8.2
chr9_+_1225808 0.66 ENSDART00000177730
CABZ01114359.1
ENSDARG00000107255
chr21_+_45693978 0.66 ENSDART00000160324
CABZ01102047.1
ENSDARG00000099648
KN150487v1_+_17905 0.65

chr23_-_45250886 0.65 ENSDART00000163367
ENSDARG00000103727
ENSDARG00000103727
chr6_+_54231519 0.64 ENSDART00000149542
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr5_-_337100 0.64

chr2_+_53253623 0.63 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr23_-_1124499 0.63

chr13_-_45386047 0.62 ENSDART00000137566
rhd
Rh blood group, D antigen
KN150233v1_-_1233 0.62

chr14_+_51848088 0.61 ENSDART00000168874
rpl26
ribosomal protein L26
chr12_+_10015987 0.61 ENSDART00000078497
slc4a1b
solute carrier family 4 (anion exchanger), member 1b (Diego blood group)
chr12_+_7421078 0.60 ENSDART00000163114
phyhiplb
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr16_+_10974655 0.60

chr7_+_34394526 0.59

chr11_+_18817797 0.58

chr22_+_980836 0.57 ENSDART00000149743
pparda
peroxisome proliferator-activated receptor delta a
chr11_+_44035254 0.56

chr6_+_55091896 0.56

KN150503v1_-_598 0.56 ENSDART00000174608
CABZ01110189.1
ENSDARG00000108333
chr21_-_36495488 0.55

chr2_-_44893769 0.54 ENSDART00000041806
acsm3
acyl-CoA synthetase medium-chain family member 3
chr3_+_1455242 0.54 ENSDART00000065922
wbp2nl
WBP2 N-terminal like
chr21_+_5293086 0.54

chr14_+_151136 0.54 ENSDART00000165766
mcm7
minichromosome maintenance complex component 7
chr16_-_12579115 0.54 ENSDART00000147483
ephb6
eph receptor B6
chr12_+_49091872 0.53 ENSDART00000178771
CABZ01075125.4
ENSDARG00000107503
chr19_-_5448129 0.53 ENSDART00000004812
cyt1
type I cytokeratin, enveloping layer
KN150411v1_-_12184 0.52

chr8_+_54088321 0.52

chr12_+_42281154 0.52 ENSDART00000167324
ebf3a
early B-cell factor 3a
chr23_+_4440723 0.51

chr21_+_44586326 0.51

chr15_+_18710214 0.50 ENSDART00000166555
cadm1b
cell adhesion molecule 1b
chr6_-_43679553 0.50 ENSDART00000150128
foxp1b
forkhead box P1b
chr2_+_2259793 0.49 ENSDART00000109073
dsg2l
desmoglein 2 like
chr16_+_6693574 0.49

chr14_+_23296676 0.47 ENSDART00000159573
med12
mediator complex subunit 12
chr25_-_4296732 0.47

chr23_-_339083 0.47 ENSDART00000140986
uhrf1bp1
UHRF1 binding protein 1
KN150423v1_-_9765 0.46

chr10_-_36882126 0.46 ENSDART00000111104
phf12a
PHD finger protein 12a
chr9_+_19584625 0.45 ENSDART00000168357
si:dkey-281i8.1
si:dkey-281i8.1
chr18_+_30392138 0.45 ENSDART00000165450
gse1
Gse1 coiled-coil protein
chr18_+_21133694 0.45 ENSDART00000060015
chka
choline kinase alpha
chr14_-_46646556 0.44

chr2_+_28906539 0.44 ENSDART00000078232
cdh10a
cadherin 10, type 2a (T2-cadherin)
chr8_-_387982 0.43

chr15_-_3120500 0.43

chr12_-_1931281 0.43 ENSDART00000005676
ENSDART00000127937
sox9a
SRY (sex determining region Y)-box 9a
chr16_+_11027394 0.43 ENSDART00000172949
pou2f2a
POU class 2 homeobox 2a
chr12_-_28248133 0.43 ENSDART00000016283
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr23_-_7048903 0.43 ENSDART00000149656
edem2
ER degradation enhancer, mannosidase alpha-like 2
chr12_-_41128584 0.42

chr20_-_7141247 0.42 ENSDART00000160910
si:ch211-121a2.4
si:ch211-121a2.4
chr16_+_5470419 0.41

chr23_-_4919504 0.41 ENSDART00000133701
slc6a1a
solute carrier family 6 (neurotransmitter transporter), member 1a
chr10_+_33956052 0.40

chr3_+_23573114 0.40 ENSDART00000024256
hoxb6a
homeobox B6a
chr5_+_30880165 0.40 ENSDART00000098197
ENSDARG00000035471
ENSDARG00000035471
chr5_+_1164747 0.40 ENSDART00000129490
gb:bc139872
expressed sequence BC139872
chr1_+_51712192 0.40

chr10_+_213828 0.38 ENSDART00000138812
mpzl1l
myelin protein zero-like 1 like
chr17_+_23102259 0.38 ENSDART00000178403
rasgrp3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr21_+_19797559 0.37 ENSDART00000147555
ccdc80l2
coiled-coil domain containing 80 like 2
chr21_+_25588388 0.37 ENSDART00000134678
ENSDARG00000078256
ENSDARG00000078256
chr21_+_8334453 0.37 ENSDART00000055336
dennd1a
DENN/MADD domain containing 1A
chr16_+_54729975 0.37

chr21_+_19797435 0.36 ENSDART00000147555
ccdc80l2
coiled-coil domain containing 80 like 2
chr16_+_25845432 0.36

chr11_-_3888456 0.35 ENSDART00000175310
ENSDART00000082404
rpn1
ribophorin I
chr10_-_45212226 0.35 ENSDART00000170413
mrps24
mitochondrial ribosomal protein S24
chr1_-_51862897 0.34 ENSDART00000136469
acy3.2
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr16_+_68014 0.33 ENSDART00000159652
sox4b
SRY (sex determining region Y)-box 4b
KN149797v1_+_49 0.33 ENSDART00000176987
CABZ01113190.1
ENSDARG00000107708
chr23_+_11734349 0.33 ENSDART00000091416
cntn3a.1
contactin 3a, tandem duplicate 1
chr6_-_43679476 0.33 ENSDART00000150128
foxp1b
forkhead box P1b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:1901998 toxin transport(GO:1901998)
0.5 2.3 GO:0006953 acute-phase response(GO:0006953)
0.4 1.3 GO:0043703 blood vessel maturation(GO:0001955) retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.4 1.3 GO:0014819 regulation of skeletal muscle contraction(GO:0014819)
0.4 1.2 GO:2000725 cardiac cell fate commitment(GO:0060911) regulation of cardiocyte differentiation(GO:1905207) regulation of cardiac muscle cell differentiation(GO:2000725)
0.4 1.5 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.4 1.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 5.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.3 1.6 GO:0036371 protein localization to T-tubule(GO:0036371)
0.3 1.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.3 1.1 GO:0044209 AMP salvage(GO:0044209)
0.3 0.8 GO:0036073 perichondral ossification(GO:0036073)
0.3 1.0 GO:0003210 cardiac atrium formation(GO:0003210)
0.2 0.7 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.2 0.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 2.3 GO:0035141 medial fin morphogenesis(GO:0035141)
0.2 1.1 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.2 1.9 GO:0009251 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.1 0.9 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.1 1.7 GO:0060021 palate development(GO:0060021)
0.1 0.1 GO:0010885 cholesterol storage(GO:0010878) regulation of cholesterol storage(GO:0010885)
0.1 1.1 GO:0072098 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.1 0.2 GO:0003211 cardiac ventricle formation(GO:0003211)
0.1 0.5 GO:0021982 pineal gland development(GO:0021982)
0.1 1.2 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 1.3 GO:0030241 skeletal muscle thin filament assembly(GO:0030240) skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 1.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.6 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.6 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.1 1.0 GO:0019226 transmission of nerve impulse(GO:0019226)
0.1 0.7 GO:0003209 cardiac atrium morphogenesis(GO:0003209)
0.1 0.5 GO:0007343 egg activation(GO:0007343)
0.1 0.5 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.7 GO:0021754 facial nucleus development(GO:0021754)
0.1 0.4 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.1 0.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.3 GO:0006528 asparagine metabolic process(GO:0006528)
0.1 1.0 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 1.2 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 1.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.6 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.5 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.3 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.5 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.0 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.0 0.8 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 1.0 GO:0030282 bone mineralization(GO:0030282)
0.0 0.9 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.3 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 1.7 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.1 GO:0046636 negative regulation of alpha-beta T cell activation(GO:0046636) negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.3 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.2 GO:0016572 histone phosphorylation(GO:0016572)
0.0 1.1 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.7 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.1 GO:0007601 visual perception(GO:0007601)
0.0 0.2 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.3 GO:0070654 sensory epithelium regeneration(GO:0070654) epithelium regeneration(GO:1990399)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:0061386 closure of optic fissure(GO:0061386)
0.0 1.5 GO:0002040 sprouting angiogenesis(GO:0002040)
0.0 1.3 GO:0001947 heart looping(GO:0001947)
0.0 1.7 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 0.8 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.3 GO:0032543 mitochondrial translation(GO:0032543)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 2.3 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 1.0 GO:1904949 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.1 1.6 GO:0030315 T-tubule(GO:0030315)
0.1 1.3 GO:0031430 M band(GO:0031430)
0.1 1.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.7 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.4 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.3 GO:1990246 uniplex complex(GO:1990246)
0.0 4.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 1.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.5 GO:0030426 growth cone(GO:0030426)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 1.7 GO:0042641 actomyosin(GO:0042641)
0.0 0.5 GO:0042555 MCM complex(GO:0042555)
0.0 0.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 1.8 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.5 GO:0070822 Sin3-type complex(GO:0070822)
0.0 1.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.8 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.8 GO:0005871 kinesin complex(GO:0005871)
0.0 7.1 GO:0005615 extracellular space(GO:0005615)
0.0 0.8 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.3 GO:0016607 nuclear speck(GO:0016607)
0.0 0.6 GO:0016323 basolateral plasma membrane(GO:0016323)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 5.1 GO:0048495 Roundabout binding(GO:0048495)
0.4 1.7 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.4 1.9 GO:0008184 phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.4 1.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.3 2.3 GO:0001948 glycoprotein binding(GO:0001948) proteoglycan binding(GO:0043394)
0.2 1.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 2.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.1 1.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 1.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.3 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 1.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.0 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.8 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:0004046 aminoacylase activity(GO:0004046)
0.1 1.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 2.3 GO:0005178 integrin binding(GO:0005178)
0.1 0.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.5 GO:0050699 WW domain binding(GO:0050699)
0.1 0.9 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.1 1.2 GO:0030165 PDZ domain binding(GO:0030165)
0.1 0.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.2 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.1 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0015924 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.1 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.5 GO:0015645 fatty acid ligase activity(GO:0015645)
0.0 0.7 GO:0043022 ribosome binding(GO:0043022)
0.0 0.3 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.2 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.3 GO:0005125 cytokine activity(GO:0005125)
0.0 0.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.7 GO:0060090 binding, bridging(GO:0060090)
0.0 5.9 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.1 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.9 PID ATR PATHWAY ATR signaling pathway
0.1 0.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.2 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 2.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 1.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.9 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.9 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.1 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 1.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.1 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 1.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)