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Results for runx1

Z-value: 1.10

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Transcription factors associated with runx1

Gene Symbol Gene ID Gene Info
ENSDARG00000087646 RUNX family transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
runx1dr10_dc_chr1_-_1254253_12542550.273.1e-01Click!

Activity profile of runx1 motif

Sorted Z-values of runx1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of runx1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr25_+_222244 1.20 ENSDART00000155344
ENSDARG00000073905
chr2_-_16896965 1.12 ENSDART00000022549
ATPase, Na+/K+ transporting, beta 3a polypeptide
chr8_-_38168395 1.02 ENSDART00000155189
PDZ and LIM domain 2 (mystique)
chr23_-_3814291 0.92

chr21_-_11539798 0.92 ENSDART00000144770
calpastatin
chr8_-_37217197 0.91 ENSDART00000178556
RNA binding motif protein 39b
chr4_+_50923792 0.86 ENSDART00000161370
ENSDARG00000100076
chr2_+_36916494 0.85 ENSDART00000084859
RAB GTPase activating protein 1-like 2
chr9_-_23307419 0.83 ENSDART00000020884
LY6/PLAUR domain containing 6
chr16_-_9978112 0.81 ENSDART00000149312
neurocalcin delta a
chr11_-_11591394 0.73 ENSDART00000142208
zgc:110712
chr11_+_5467173 0.71

chr11_+_37639045 0.71 ENSDART00000111157
si:ch211-112f3.4
chr8_+_20125687 0.70 ENSDART00000124809
acyl-CoA synthetase bubblegum family member 2
chr25_+_5232865 0.70

chr16_-_45943282 0.69 ENSDART00000133213
antifreeze protein type IV
chr15_-_26703761 0.69 ENSDART00000087632
ENSDARG00000079340
chr23_+_44839349 0.69 ENSDART00000143399
calmodulin binding transcription activator 2
chr21_-_19280266 0.69 ENSDART00000141596
glycerol-3-phosphate acyltransferase 3
chr16_-_17148579 0.67 ENSDART00000138715
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr5_-_17542077 0.67 ENSDART00000144898
ring finger protein 215
chr1_-_50066633 0.67

chr7_-_24093289 0.66 ENSDART00000064789
thioredoxin
chr16_-_51390400 0.66 ENSDART00000148894
serpin peptidase inhibitor, clade B (ovalbumin), member 14
chr18_+_22120282 0.65 ENSDART00000147230
zgc:158868
chr12_+_38382027 0.64 ENSDART00000021069
ribosomal protein L38
chr10_-_43924675 0.64 ENSDART00000052307
arrestin domain containing 3b
chr9_-_14533551 0.63 ENSDART00000056103
neuropilin 2b
chr11_-_22450582 0.63

chr1_-_11439671 0.63 ENSDART00000164817
microsomal triglyceride transfer protein
chr3_+_54506912 0.62 ENSDART00000135913
si:ch211-74m13.1
chr13_-_42986821 0.60 ENSDART00000164439
si:ch211-106f21.1
chr14_-_3264798 0.60 ENSDART00000171601
im:7150988
chr25_+_5233045 0.59

chr13_-_39033893 0.58 ENSDART00000045434
collagen, type IX, alpha 1b
chr8_-_50992034 0.58 ENSDART00000004065
zgc:91909
chr2_-_6139895 0.58 ENSDART00000147509
si:ch211-284b7.3
chr7_+_25758469 0.58 ENSDART00000101126
arachidonate 12-lipoxygenase
chr22_+_2921305 0.57 ENSDART00000143258
centrosomal protein 19
chr7_-_48392300 0.57

chr8_+_21321765 0.56 ENSDART00000131691
aminolevulinate, delta-, synthase 2
chr25_-_34645938 0.55 ENSDART00000108895
ENSDARG00000077587
chr6_-_7281412 0.55 ENSDART00000053776
FK506 binding protein 11
chr21_+_34895120 0.55 ENSDART00000157904
ENSDART00000135806
si:dkey-71d15.2
chr2_-_58822653 0.54 ENSDART00000114286
ENSDART00000114181
SURP and G patch domain containing 1
chr20_+_54289892 0.54 ENSDART00000060444
ribosomal protein S29
chr3_+_3955069 0.54 ENSDART00000092393
phospholipase B domain containing 1
chr2_-_44429891 0.54 ENSDART00000163040
ENSDART00000056372
ENSDART00000109251
ENSDART00000166923
ENSDART00000132682
myelin protein zero
chr4_-_76620869 0.53

chr13_-_36996246 0.53 ENSDART00000133242
spectrin repeat containing, nuclear envelope 2b
chr5_+_60790602 0.52 ENSDART00000127521
leucine-rich repeats and WD repeat domain containing 1
chr24_+_19374200 0.52 ENSDART00000056081
ENSDART00000027022
sulfatase 1
chr6_+_7092350 0.52 ENSDART00000049695
ENSDART00000136088
ENSDART00000083424
ENSDART00000125912
DAZ interacting zinc finger protein 1
chr3_+_37645350 0.51 ENSDART00000134524
ribosomal protein S11
chr12_+_6007990 0.51 ENSDART00000091868
glucose-6-phosphatase a, catalytic subunit, tandem duplicate 2
chr15_+_34131126 0.51 ENSDART00000169487
von Willebrand factor D and EGF domains
chr14_-_2008649 0.50 ENSDART00000161817
protocadherin 2 gamma 16
chr7_+_5372830 0.50 ENSDART00000135271
myeloid associated differentiation marker
chr7_+_65532390 0.50 ENSDART00000156683
ENSDARG00000097673
chr2_-_3202918 0.50

chr8_+_7301525 0.50 ENSDART00000092347
ssu-2 homolog, related sequence 1
chr4_-_72146177 0.50 ENSDART00000150546
si:dkey-262g12.3
chr1_-_54331157 0.49 ENSDART00000083572
zgc:136864
chr6_+_30681170 0.49 ENSDART00000112294
tetratricopeptide repeat domain 22
chr1_-_11163480 0.49 ENSDART00000033361
tweety family member 3b
chr14_+_38445969 0.49 ENSDART00000164440
si:ch211-195b11.3
chr7_-_6296880 0.49 ENSDART00000172954
si:ch1073-153i20.4
chr12_+_16403743 0.48 ENSDART00000058665
kinesin family member 20Bb
chr17_+_24613874 0.48 ENSDART00000093004
mitogen-activated protein kinase kinase kinase kinase 3b
chr12_+_31558667 0.47 ENSDART00000152971
dynamin binding protein
chr2_+_1767497 0.47 ENSDART00000029371
desmoplakin a
chr14_+_47229400 0.47 ENSDART00000136045
microsomal glutathione S-transferase 2
chr8_+_32604349 0.47 ENSDART00000126833
hemicentin 2
chr11_-_471166 0.46 ENSDART00000154888
CCHC-type zinc finger, nucleic acid binding protein b
chr6_+_56163589 0.46 ENSDART00000150219
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr11_+_7570027 0.45 ENSDART00000091550
adhesion G protein-coupled receptor L2a
chr13_-_5953330 0.45 ENSDART00000099224
deltaD
chr18_+_40364675 0.44 ENSDART00000098791
ENSDART00000049171
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr12_-_26760324 0.44 ENSDART00000047724
zinc finger E-box binding homeobox 1b
chr20_+_52653111 0.44 ENSDART00000057980
tissue specific transplantation antigen P35B
chr16_-_51390484 0.43 ENSDART00000148894
serpin peptidase inhibitor, clade B (ovalbumin), member 14
chr2_-_9950224 0.43 ENSDART00000146407
si:ch1073-170o4.1
chr16_-_29593569 0.43 ENSDART00000150028
one cut domain, family member, like
chr17_-_42293039 0.42 ENSDART00000014296
forkhead box A2
chr22_-_613948 0.42 ENSDART00000148692
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a
chr11_-_40415291 0.42

chr10_+_36254196 0.42 ENSDART00000114102
cytochrome c oxidase assembly factor 4 homolog
chr6_+_45917081 0.41 ENSDART00000149450
ENSDART00000149642
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr16_+_4288700 0.41 ENSDART00000159694
inositol polyphosphate-5-phosphatase B
chr11_+_7570097 0.41 ENSDART00000091550
adhesion G protein-coupled receptor L2a
chr4_-_12796590 0.41 ENSDART00000075127
beta-2-microglobulin
chr17_+_15425559 0.41 ENSDART00000026180
fatty acid binding protein 7, brain, a
chr1_-_24486146 0.41 ENSDART00000144711
transmembrane protein 154
chr11_-_42096921 0.40

chr23_+_42396834 0.40 ENSDART00000164249
cytochrome P450, family 2, subfamily AA, polypeptide 4
chr15_-_1061845 0.40 ENSDART00000156003
zinc finger protein 1010
chr12_-_5383331 0.40 ENSDART00000152622
ENSDART00000028043
NOC3-like DNA replication regulator
chr19_+_1356824 0.40 ENSDART00000081779
zinc finger, DHHC-type containing 3b
chr10_+_33227967 0.39 ENSDART00000159666
myosin, light chain 10, regulatory
chr7_-_26153788 0.39

chr10_-_8094671 0.39 ENSDART00000099033
zgc:158494
chr20_-_14158114 0.39 ENSDART00000009549
Rh-associated glycoprotein
chr9_-_216905 0.39 ENSDART00000163068
achalasia, adrenocortical insufficiency, alacrimia
chr20_+_32503118 0.39 ENSDART00000018640
sorting nexin 3
chr9_-_56292487 0.38 ENSDART00000151720
si:ch211-39i22.1
chr4_+_29817277 0.38 ENSDART00000167186
ENSDARG00000104750
chr21_-_2143830 0.38

KN149817v1_+_2207 0.38

chr4_-_2595775 0.38 ENSDART00000132581
ENSDART00000019508
cysteine and glycine-rich protein 2
chr6_-_43273456 0.38

chr8_-_16662185 0.38 ENSDART00000076542
retinal pigment epithelium-specific protein 65b
chr22_-_3264630 0.38 ENSDART00000170992
si:zfos-943e10.1
chr8_+_10267246 0.37 ENSDART00000159312
ENSDART00000160766
Pim-1 proto-oncogene, serine/threonine kinase
chr18_+_27753985 0.37 ENSDART00000141835
tetraspanin 18b
chr5_+_35839198 0.37 ENSDART00000102973
ENSDART00000103020
ectodysplasin A
chr24_+_19374099 0.37 ENSDART00000056081
ENSDART00000027022
sulfatase 1
chr11_-_11347349 0.37 ENSDART00000173019
mitochondrial ribosomal protein L4
chr20_-_47123598 0.36 ENSDART00000100320
DNA (cytosine-5-)-methyltransferase 3 alpha a
chr20_+_34640226 0.36 ENSDART00000076946
ENSDARG00000054723
chr23_+_8671759 0.36 ENSDART00000129997
regulator of G protein signaling 19
chr24_-_37800277 0.36 ENSDART00000141414
zgc:112185
chr7_-_6295302 0.36 ENSDART00000173199
si:ch1073-153i20.5
chr9_-_11589126 0.36 ENSDART00000146832
crystallin, beta A2b
chr7_-_6273677 0.36 ENSDART00000173419
si:ch73-368j24.1
chr22_-_2921219 0.36 ENSDART00000092991
phosphatidylinositol glycan anchor biosynthesis, class X
chr12_+_3043444 0.36 ENSDART00000149427
sarcoglycan, alpha
chr3_-_19218660 0.35 ENSDART00000132987
sphingosine-1-phosphate receptor 5a
chr15_-_15532980 0.35 ENSDART00000004220
ENSDART00000131259
RAB34, member RAS oncogene family a
chr5_+_34022151 0.35 ENSDART00000141338
ectodermal-neural cortex 1
chr14_-_31184501 0.35

chr14_+_24548729 0.35

chr23_+_36208816 0.35 ENSDART00000127174
heterogeneous nuclear ribonucleoprotein A1b
chr3_+_27582726 0.35 ENSDART00000019004
Rho GDP dissociation inhibitor (GDI) gamma
chr4_+_72347854 0.35 ENSDART00000174148
ENSDARG00000105790
chr19_+_7576862 0.34 ENSDART00000010862
mitochondrial ribosomal protein L24
chr15_-_35394535 0.34 ENSDART00000144153
mitochondrial fission factor
chr7_+_5790032 0.34 ENSDART00000173025
si:dkey-23a13.9
chr5_+_23092679 0.34

chr8_-_41266057 0.34 ENSDART00000108518
ring finger protein 10
chr22_-_583831 0.34 ENSDART00000106636
serine/arginine-rich splicing factor 3b
chr23_+_27052594 0.34 ENSDART00000109712
ENSDART00000018654
Rho family GTPase 1b
chr15_-_20254259 0.34 ENSDART00000157149
exocyst complex component 3-like 2b
chr5_+_23093316 0.34 ENSDART00000006983
K(lysine) acetyltransferase 5a
chr20_+_4512872 0.34

chr7_-_11812634 0.34 ENSDART00000101537
mex-3 RNA binding family member B
chr5_-_22090338 0.33

chr5_+_3965645 0.33 ENSDART00000100061
peroxiredoxin 4
chr14_-_26138828 0.33 ENSDART00000140173
si:dkeyp-110e4.6
chr5_+_69369417 0.33

chr21_-_14729288 0.33 ENSDART00000067001
nucleolar complex associated 4 homolog
chr21_+_22808694 0.33 ENSDART00000065555
baculoviral IAP repeat containing 2
chr23_+_23730717 0.32

chr7_+_20215723 0.32 ENSDART00000173724
ENSDART00000173773
si:dkey-33c9.8
chr19_-_9192541 0.32

chr23_-_29138952 0.32 ENSDART00000002812
castor zinc finger 1
chr6_+_59788008 0.32

chr14_+_37206949 0.32

chr13_+_24132617 0.32 ENSDART00000135992
ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr3_+_22962233 0.32 ENSDART00000142884
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a
chr13_-_39821399 0.32 ENSDART00000056996
secreted frizzled-related protein 5
chr23_-_4990023 0.32 ENSDART00000142699
tafazzin
chr2_+_48052054 0.31 ENSDART00000159701
finTRIM family, member 23
chr6_-_34955205 0.31 ENSDART00000131610
SERPINE1 mRNA binding protein 1a
chr5_-_20375703 0.31 ENSDART00000134697
phosphoinositide-3-kinase interacting protein 1
chr1_+_32485317 0.31 ENSDART00000136761
protein kinase, X-linked
chr7_+_31608828 0.31 ENSDART00000138491
myosin binding protein C, cardiac
chr23_-_16755682 0.31 ENSDART00000020810
syndecan binding protein (syntenin) 2
chr11_-_34310102 0.31 ENSDART00000077883
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a
chr22_+_9841541 0.31 ENSDART00000141085
si:dkey-253d23.4
chr1_-_37475807 0.31 ENSDART00000020409
heart and neural crest derivatives expressed 2
chr10_+_29964412 0.31 ENSDART00000117710
Small nucleolar RNA SNORD14
chr5_+_61678124 0.31 ENSDART00000074117
aspartoacylase
chr3_+_19471228 0.30 ENSDART00000025358
integrin beta 3a
chr4_-_6443699 0.30

chr13_+_44720106 0.30 ENSDART00000017770
zinc finger and BTB domain containing 8 opposite strand
chr1_-_11163282 0.30 ENSDART00000033361
tweety family member 3b
chr16_+_26566014 0.30 ENSDART00000041787
tripartite motif containing 35-28
chr4_+_75262389 0.30 ENSDART00000174100
ENSDARG00000105672
chr7_+_31608878 0.30 ENSDART00000099789
myosin binding protein C, cardiac
chr11_+_7570326 0.30 ENSDART00000091550
adhesion G protein-coupled receptor L2a
KN150703v1_-_32804 0.30

chr2_+_33206349 0.29 ENSDART00000145588
ring finger protein 220a
chr19_-_10737772 0.29 ENSDART00000081379
oleoyl-ACP hydrolase
chr8_-_14054145 0.29 ENSDART00000137857
si:ch211-229n2.7
chr4_-_71367238 0.29 ENSDART00000165327
ENSDARG00000100390
chr2_-_30071872 0.29 ENSDART00000056747
sonic hedgehog b
chr7_-_60525749 0.29 ENSDART00000136999
pyruvate carboxylase b
chr7_-_73631286 0.29 ENSDART00000129254
zgc:173552
chr11_-_18068313 0.29

chr18_+_31094840 0.29 ENSDART00000023539
cytochrome b-245, alpha polypeptide
chr11_-_22450525 0.29

chr19_-_3880722 0.29 ENSDART00000169639
ENSDARG00000101034
chr19_+_5501487 0.29 ENSDART00000132874
eukaryotic translation initiation factor 1B
chr2_-_57133471 0.28

chr18_-_40518772 0.28 ENSDART00000021372
cholinergic receptor, nicotinic, alpha 5
chr8_-_49315811 0.28 ENSDART00000147020
prickle homolog 3
chr11_-_42933969 0.28 ENSDART00000172929
spectrin, beta, non-erythrocytic 1
chr9_-_29056763 0.28 ENSDART00000060321
ENSDARG00000056704
chr6_+_247024 0.28 ENSDART00000123769
ribosomal protein S19 binding protein 1
chr5_+_56667388 0.28 ENSDART00000012586
solute carrier family 31 (copper transporter), member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.2 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.2 0.9 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.2 0.8 GO:0019372 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 0.2 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.2 0.5 GO:0043589 skin morphogenesis(GO:0043589)
0.2 0.6 GO:0003210 cardiac atrium formation(GO:0003210)
0.1 0.4 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.1 0.6 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.1 0.4 GO:0051101 regulation of DNA binding(GO:0051101)
0.1 0.4 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 0.4 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.4 GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)(GO:0000388)
0.1 0.4 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.1 0.4 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
0.1 0.7 GO:0071169 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.1 0.3 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.1 0.8 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 0.9 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 0.3 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.1 0.4 GO:0071869 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.1 0.5 GO:0031646 positive regulation of neurological system process(GO:0031646)
0.1 0.7 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.3 GO:0042554 superoxide anion generation(GO:0042554)
0.1 0.4 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 0.3 GO:1905178 regulation of cardiac muscle tissue regeneration(GO:1905178)
0.1 0.3 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1 0.2 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.1 0.3 GO:0010939 regulation of necrotic cell death(GO:0010939) regulation of necroptotic process(GO:0060544)
0.1 0.3 GO:1903726 negative regulation of phospholipid metabolic process(GO:1903726)
0.1 0.2 GO:0097702 response to oscillatory fluid shear stress(GO:0097702) cellular response to oscillatory fluid shear stress(GO:0097704)
0.1 1.0 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 0.6 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.1 0.4 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.1 0.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 0.4 GO:0042539 hypotonic response(GO:0006971) response to salt stress(GO:0009651) hypotonic salinity response(GO:0042539)
0.1 0.6 GO:0060956 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.1 0.2 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.1 0.2 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.2 GO:1990168 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.1 0.3 GO:0051601 exocyst localization(GO:0051601)
0.1 0.2 GO:0006407 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.1 0.2 GO:0006970 response to osmotic stress(GO:0006970)
0.1 0.4 GO:0021781 oligodendrocyte cell fate commitment(GO:0021779) glial cell fate commitment(GO:0021781)
0.1 0.3 GO:0046471 cardiolipin metabolic process(GO:0032048) phosphatidylglycerol metabolic process(GO:0046471)
0.1 0.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.4 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.2 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.0 0.1 GO:2000253 negative regulation of lipid transport(GO:0032369) endocrine process(GO:0050886) positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.3 GO:0035094 response to nicotine(GO:0035094)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.7 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782) protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.3 GO:0070527 platelet aggregation(GO:0070527)
0.0 0.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.5 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.2 GO:1900024 regulation of substrate adhesion-dependent cell spreading(GO:1900024)
0.0 0.4 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.2 GO:0070861 regulation of COPII vesicle coating(GO:0003400) regulation of protein exit from endoplasmic reticulum(GO:0070861) positive regulation of protein exit from endoplasmic reticulum(GO:0070863) regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis(GO:0090113)
0.0 0.1 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.0 0.9 GO:0042476 odontogenesis(GO:0042476)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.6 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.3 GO:0045453 bone resorption(GO:0045453)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.0 0.2 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 1.8 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.5 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.0 0.1 GO:0036037 CD8-positive, alpha-beta T cell activation(GO:0036037)
0.0 0.8 GO:0043588 skin development(GO:0043588)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.7 GO:0006896 Golgi to vacuole transport(GO:0006896)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0006683 galactosylceramide catabolic process(GO:0006683) galactolipid catabolic process(GO:0019376)
0.0 0.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.2 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.0 1.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.0 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.0 0.1 GO:0046416 D-amino acid catabolic process(GO:0019478) D-serine catabolic process(GO:0036088) D-amino acid metabolic process(GO:0046416) D-serine metabolic process(GO:0070178)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.2 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.1 GO:0070544 negative regulation of ossification(GO:0030279) histone H3-K4 demethylation(GO:0034720) histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.0 0.1 GO:0031061 negative regulation of histone methylation(GO:0031061)
0.0 0.1 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.0 0.2 GO:0045471 response to ethanol(GO:0045471)
0.0 0.6 GO:0007632 visual behavior(GO:0007632)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.4 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.0 1.1 GO:0006821 chloride transport(GO:0006821)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.4 GO:0060030 dorsal convergence(GO:0060030)
0.0 0.0 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.0 0.7 GO:0043542 endothelial cell migration(GO:0043542)
0.0 0.2 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.0 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379) cellular response to fatty acid(GO:0071398)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.0 0.1 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.2 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.3 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0007638 mechanosensory behavior(GO:0007638) membrane depolarization during action potential(GO:0086010)
0.0 0.7 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.1 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0016103 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.0 0.1 GO:0019320 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) hexose catabolic process(GO:0019320) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.1 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.2 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.0 0.1 GO:0051567 histone H3-K9 methylation(GO:0051567) histone H3-K9 modification(GO:0061647)
0.0 0.4 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.2 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0050670 regulation of mononuclear cell proliferation(GO:0032944) regulation of T cell proliferation(GO:0042129) regulation of lymphocyte proliferation(GO:0050670) regulation of leukocyte proliferation(GO:0070663)
0.0 0.2 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.0 0.2 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.0 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.0 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.6 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.2 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.4 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:1904949 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.1 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.7 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.4 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.2 GO:0034709 methylosome(GO:0034709)
0.1 0.2 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.7 GO:0014704 intercalated disc(GO:0014704)
0.1 0.2 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.1 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0043209 myelin sheath(GO:0043209)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 1.0 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.1 GO:0061702 inflammasome complex(GO:0061702)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 1.0 GO:0031941 filamentous actin(GO:0031941)
0.0 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 1.3 GO:0005795 Golgi stack(GO:0005795)
0.0 0.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.0 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.7 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.0 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.0 GO:0044304 main axon(GO:0044304)
0.0 0.5 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.2 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.9 GO:0005814 centriole(GO:0005814)
0.0 0.6 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 1.6 GO:0030424 axon(GO:0030424)
0.0 0.5 GO:0030018 Z disc(GO:0030018)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 0.8 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.4 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.4 GO:0019807 aspartoacylase activity(GO:0019807)
0.1 0.9 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 1.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.3 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.1 0.9 GO:0005113 patched binding(GO:0005113)
0.1 0.3 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.6 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.7 GO:0016405 CoA-ligase activity(GO:0016405)
0.1 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.1 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.5 GO:0042805 actinin binding(GO:0042805)
0.1 1.1 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0004736 pyruvate carboxylase activity(GO:0004736)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.4 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.4 GO:0030546 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.2 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.1 GO:0030623 U5 snRNA binding(GO:0030623)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.1 GO:0004336 galactosylceramidase activity(GO:0004336)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0015038 peptide disulfide oxidoreductase activity(GO:0015037) glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0004937 alpha-adrenergic receptor activity(GO:0004936) alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.4 GO:0005112 Notch binding(GO:0005112) PDZ domain binding(GO:0030165)
0.0 0.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0071855 neuropeptide hormone activity(GO:0005184) neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.1 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.4 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0015149 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.0 0.1 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 1.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.1 GO:0038064 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.6 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.5 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0008443 6-phosphofructokinase activity(GO:0003872) phosphofructokinase activity(GO:0008443) fructose-6-phosphate binding(GO:0070095)
0.0 2.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0005344 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.0 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.7 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0019003 GDP binding(GO:0019003)
0.0 0.0 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.0 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 1.0 GO:0020037 heme binding(GO:0020037)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 1.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 PID ATF2 PATHWAY ATF-2 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.7 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 0.7 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.3 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.4 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.2 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)