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Results for runx2a+runx2b

Z-value: 1.89

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Transcription factors associated with runx2a+runx2b

Gene Symbol Gene ID Gene Info
runx2a
ENSDARG00000040261 RUNX family transcription factor 2a
runx2b
ENSDARG00000059233 RUNX family transcription factor 2b

Activity profile of runx2a+runx2b motif

Sorted Z-values of runx2a+runx2b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of runx2a+runx2b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_-_24093289 8.82 ENSDART00000064789
txn
thioredoxin
chr21_-_99353 5.71 ENSDART00000040422
bhmt
betaine-homocysteine methyltransferase
chr7_-_50827308 5.07 ENSDART00000121574
col4a6
collagen, type IV, alpha 6
chr11_+_37639045 4.63 ENSDART00000111157
si:ch211-112f3.4
si:ch211-112f3.4
chr13_-_39033893 4.04 ENSDART00000045434
col9a1b
collagen, type IX, alpha 1b
chr24_-_4941954 3.97 ENSDART00000127597
zic1
zic family member 1 (odd-paired homolog, Drosophila)
chr25_+_5232865 3.95

chr7_+_25758469 3.86 ENSDART00000101126
alox12
arachidonate 12-lipoxygenase
chr23_+_23730717 3.83

chr9_-_37940101 3.78 ENSDART00000087663
sema5ba
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5Ba
chr8_+_23759741 3.62 ENSDART00000162924
SCARNA2
Small Cajal body-specific RNA 2
chr23_+_36002332 3.58 ENSDART00000103139
hoxc8a
homeobox C8a
chr9_-_14533551 3.41 ENSDART00000056103
nrp2b
neuropilin 2b
chr16_-_9978112 3.33 ENSDART00000149312
ncalda
neurocalcin delta a
chr5_+_56667388 3.32 ENSDART00000012586
slc31a1
solute carrier family 31 (copper transporter), member 1
chr9_-_23307419 3.24 ENSDART00000020884
lypd6
LY6/PLAUR domain containing 6
chr25_+_7858886 3.23 ENSDART00000171904
ucmab
upper zone of growth plate and cartilage matrix associated b
chr1_+_46537108 3.23

chr14_+_38445969 3.21 ENSDART00000164440
si:ch211-195b11.3
si:ch211-195b11.3
chr6_+_56163589 3.19 ENSDART00000150219
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr23_+_36023748 3.16

chr24_+_11194381 3.06 ENSDART00000143171
si:dkey-12l12.1
si:dkey-12l12.1
chr6_-_7281412 3.03 ENSDART00000053776
fkbp11
FK506 binding protein 11
chr21_+_13063614 3.02

chr14_-_23953804 3.00 ENSDART00000114169
bnip1a
BCL2/adenovirus E1B interacting protein 1a
chr20_+_52653111 2.99 ENSDART00000057980
tsta3
tissue specific transplantation antigen P35B
chr1_+_1953714 2.98 ENSDART00000164488
ENSDART00000167050
ENSDART00000122626
ENSDART00000128187
mbnl2
muscleblind-like splicing regulator 2
chr19_+_31046291 2.98 ENSDART00000052124
fam49al
family with sequence similarity 49, member A-like
chr11_-_23151247 2.95

chr1_+_1541977 2.94 ENSDART00000048828
atp1a1a.4
ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 4
chr21_-_20305406 2.92 ENSDART00000065659
rbp4l
retinol binding protein 4, like
chr21_-_7703717 2.89 ENSDART00000158852
egfl7
EGF-like-domain, multiple 7
chr11_+_8119829 2.85 ENSDART00000011183
prkacba
protein kinase, cAMP-dependent, catalytic, beta a
chr21_-_11539798 2.84 ENSDART00000144770
cast
calpastatin
chr24_-_21778717 2.81 ENSDART00000131944
tagln3b
transgelin 3b
chr2_-_30198789 2.80 ENSDART00000019149
rpl7
ribosomal protein L7
chr7_-_11812634 2.79 ENSDART00000101537
mex3b
mex-3 RNA binding family member B
chr20_-_14158114 2.77 ENSDART00000009549
rhag
Rh-associated glycoprotein
chr23_-_2084541 2.72 ENSDART00000091532
ndnf
neuron-derived neurotrophic factor
chr22_+_9841541 2.70 ENSDART00000141085
si:dkey-253d23.4
si:dkey-253d23.4
chr9_-_29056763 2.70 ENSDART00000060321
ENSDARG00000056704
ENSDARG00000056704
chr24_+_17125429 2.69 ENSDART00000017605
spag6
sperm associated antigen 6
chr1_-_37475807 2.64 ENSDART00000020409
hand2
heart and neural crest derivatives expressed 2
chr4_-_19895115 2.64 ENSDART00000105967
cacna2d1a
calcium channel, voltage-dependent, alpha 2/delta subunit 1a
chr11_-_11591394 2.63 ENSDART00000142208
zgc:110712
zgc:110712
chr20_-_35343242 2.62 ENSDART00000113294
fzd3a
frizzled class receptor 3a
chr12_-_8448482 2.62 ENSDART00000062855
egr2b
early growth response 2b
chr18_-_44914637 2.62 ENSDART00000169636
si:ch211-71n6.4
si:ch211-71n6.4
chr3_+_31490043 2.60 ENSDART00000076636
fzd2
frizzled class receptor 2
chr19_+_22478256 2.60 ENSDART00000100181
sall3b
spalt-like transcription factor 3b
chr20_+_20600211 2.55 ENSDART00000036124
six1b
SIX homeobox 1b
chr18_+_38307946 2.54 ENSDART00000134247
lmo2
LIM domain only 2 (rhombotin-like 1)
chr22_-_10430130 2.53 ENSDART00000064801
ogn
osteoglycin
chr3_-_40159349 2.52 ENSDART00000055186
atp5j2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2
chr10_-_25695574 2.52 ENSDART00000110751
tiam1a
T-cell lymphoma invasion and metastasis 1a
chr19_+_16318256 2.51 ENSDART00000137189
ptprua
protein tyrosine phosphatase, receptor type, U, a
chr15_-_42250788 2.49 ENSDART00000015843
pax3b
paired box 3b
chr7_+_25587183 2.47 ENSDART00000148780
mtmr1a
myotubularin related protein 1a
chr16_-_29593569 2.46 ENSDART00000150028
onecutl
one cut domain, family member, like
chr7_-_48392300 2.46

chr14_+_6117282 2.43 ENSDART00000051556
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr13_+_22545318 2.41 ENSDART00000143312
zgc:193505
zgc:193505
chr2_+_21067708 2.41 ENSDART00000148400
ENSDART00000021168
rxrga
retinoid x receptor, gamma a
chr13_-_33574216 2.39 ENSDART00000065435
cst3
cystatin C (amyloid angiopathy and cerebral hemorrhage)
chr8_+_21321765 2.39 ENSDART00000131691
alas2
aminolevulinate, delta-, synthase 2
chr16_-_42063851 2.39 ENSDART00000045403
etv2
ets variant 2
chr23_+_28656263 2.38 ENSDART00000020296
nadl1.2
neural adhesion molecule L1.2
chr2_+_24649130 2.34 ENSDART00000078972
fitm1
fat storage-inducing transmembrane protein 1
chr25_+_30746445 2.32 ENSDART00000156916
lsp1
lymphocyte-specific protein 1
chr2_-_40170303 2.32 ENSDART00000165602
epha4a
eph receptor A4a
chr9_-_42894582 2.28 ENSDART00000144744
col5a2a
collagen, type V, alpha 2a
chr19_-_22904687 2.28 ENSDART00000141503
pleca
plectin a
chr5_+_34022151 2.26 ENSDART00000141338
enc1
ectodermal-neural cortex 1
chr11_-_38940966 2.26 ENSDART00000105133
wnt4a
wingless-type MMTV integration site family, member 4a
chr10_-_43924675 2.25 ENSDART00000052307
arrdc3b
arrestin domain containing 3b
chr20_+_54289892 2.23 ENSDART00000060444
rps29
ribosomal protein S29
chr19_+_17461581 2.23 ENSDART00000159838
lye
lymphocyte antigen-6, epidermis
chr2_-_30675594 2.23 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr18_+_12207888 2.22

chr6_+_45917081 2.21 ENSDART00000149450
ENSDART00000149642
h6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr12_-_26760324 2.20 ENSDART00000047724
zeb1b
zinc finger E-box binding homeobox 1b
chr15_+_19902697 2.20 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr13_-_42986821 2.19 ENSDART00000164439
si:ch211-106f21.1
si:ch211-106f21.1
chr15_-_10345337 2.16

chr19_+_14103214 2.16

chr1_-_24486146 2.15 ENSDART00000144711
tmem154
transmembrane protein 154
chr11_-_18004437 2.14 ENSDART00000125800
CABZ01112210.1
ENSDARG00000088766
chr4_+_15870605 2.13 ENSDART00000178674
BX004864.1
ENSDARG00000107641
chr3_+_19471228 2.13 ENSDART00000025358
itgb3a
integrin beta 3a
chr8_-_4903896 2.12 ENSDART00000004986
igsf9b
immunoglobulin superfamily, member 9b
chr21_+_7844259 2.12 ENSDART00000027268
otpa
orthopedia homeobox a
chr15_-_23441268 2.08 ENSDART00000078570
c1qtnf5
C1q and TNF related 5
chr1_+_49894978 2.08 ENSDART00000020412
pkd2
polycystic kidney disease 2
chr22_+_18927612 2.08 ENSDART00000136390
hcn2b
hyperpolarization activated cyclic nucleotide-gated potassium channel 2b
chr23_-_15381030 2.07

chr16_+_33041823 2.07 ENSDART00000170157
prss35
protease, serine, 35
chr3_-_57691670 2.05 ENSDART00000156522
cant1a
calcium activated nucleotidase 1a
chr15_-_18066180 2.03 ENSDART00000154524
phldb1b
pleckstrin homology-like domain, family B, member 1b
chr1_-_44886649 2.03

chr21_-_26459113 2.02 ENSDART00000157255
cd248b
CD248 molecule, endosialin b
chr23_-_20837809 2.01 ENSDART00000089750
znf362b
zinc finger protein 362b
chr22_+_13862110 1.99 ENSDART00000105711
sh3bp4a
SH3-domain binding protein 4a
chr8_-_41266057 1.99 ENSDART00000108518
rnf10
ring finger protein 10
chr2_-_9950224 1.97 ENSDART00000146407
si:ch1073-170o4.1
si:ch1073-170o4.1
chr20_-_35343057 1.97 ENSDART00000113294
fzd3a
frizzled class receptor 3a
KN150256v1_-_9467 1.96

chr11_+_5467173 1.95

chr3_-_39031305 1.95 ENSDART00000022393
si:dkeyp-57f11.2
si:dkeyp-57f11.2
chr9_+_36051713 1.93 ENSDART00000134447
rcan1a
regulator of calcineurin 1a
chr16_-_16796313 1.91

chr24_+_37834148 1.88

chr25_-_22890657 1.86

chr2_+_54060488 1.86 ENSDART00000167239
CABZ01050249.1
ENSDARG00000099376
chr13_-_36996246 1.85 ENSDART00000133242
syne2b
spectrin repeat containing, nuclear envelope 2b
chr8_+_7297981 1.85 ENSDART00000170975
BX469901.2
ENSDARG00000103232
chr14_+_34174018 1.84 ENSDART00000024440
foxi3b
forkhead box I3b
chr16_+_38327295 1.79 ENSDART00000085143
bnipl
BCL2/adenovirus E1B 19kD interacting protein, like
chr17_-_9869142 1.79 ENSDART00000008355
cfl2
cofilin 2 (muscle)
chr4_-_11604184 1.76 ENSDART00000170136
net1
neuroepithelial cell transforming 1
chr15_+_30442890 1.76 ENSDART00000048847
nos2b
nitric oxide synthase 2b, inducible
chr14_+_4489377 1.75 ENSDART00000041468
ap1ar
adaptor-related protein complex 1 associated regulatory protein
chr16_-_24280209 1.73 ENSDART00000048599
rps19
ribosomal protein S19
chr17_-_2513630 1.73 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr5_+_26252925 1.73

chr24_+_19374200 1.72 ENSDART00000056081
ENSDART00000027022
sulf1
sulfatase 1
chr6_-_7281346 1.71 ENSDART00000133096
fkbp11
FK506 binding protein 11
chr10_+_10393377 1.71 ENSDART00000109432
cercam
cerebral endothelial cell adhesion molecule
chr4_-_16417703 1.71 ENSDART00000013085
dcn
decorin
chr16_+_42067930 1.71 ENSDART00000102789
fli1b
Fli-1 proto-oncogene, ETS transcription factor b
chr23_+_34079219 1.67 ENSDART00000132668
si:ch211-207e14.4
si:ch211-207e14.4
chr18_+_6692992 1.67

chr5_-_31845371 1.66 ENSDART00000157295
ENSDART00000159522
ncs1a
neuronal calcium sensor 1a
chr2_-_30071872 1.63 ENSDART00000056747
shhb
sonic hedgehog b
chr7_-_33558771 1.63 ENSDART00000074729
uacab
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr20_-_20634087 1.62 ENSDART00000125039
six6b
SIX homeobox 6b
chr4_-_19895001 1.62 ENSDART00000014440
cacna2d1a
calcium channel, voltage-dependent, alpha 2/delta subunit 1a
chr1_-_38189932 1.61 ENSDART00000136102
vegfc
vascular endothelial growth factor c
chr7_-_18346474 1.59

chr22_+_5657904 1.59 ENSDART00000138102
dnase1l4.2
deoxyribonuclease 1 like 4, tandem duplicate 2
chr7_+_25649559 1.59 ENSDART00000026295
arrb2b
arrestin, beta 2b
chr13_-_4204592 1.58 ENSDART00000122406
znf318
zinc finger protein 318
chr9_-_47041677 1.57 ENSDART00000054137
igfbp5b
insulin-like growth factor binding protein 5b
chr11_-_18004011 1.57 ENSDART00000125800
CABZ01112210.1
ENSDARG00000088766
chr17_+_48999061 1.56 ENSDART00000177390
tiam2a
T-cell lymphoma invasion and metastasis 2a
chr4_+_8531280 1.55 ENSDART00000162065
wnt5b
wingless-type MMTV integration site family, member 5b
chr15_-_35394535 1.54 ENSDART00000144153
mff
mitochondrial fission factor
chr7_+_59773957 1.54 ENSDART00000051524
etnppl
ethanolamine-phosphate phospho-lyase
chr22_+_17091411 1.53 ENSDART00000170076
frem1b
Fras1 related extracellular matrix 1b
chr13_+_1484997 1.53

chr23_-_29138952 1.52 ENSDART00000002812
casz1
castor zinc finger 1
chr1_-_19001718 1.52 ENSDART00000143303
BX323590.2
ENSDARG00000095388
chr14_-_14260824 1.51 ENSDART00000159056
si:dkey-27i16.2
si:dkey-27i16.2
chr6_-_24003717 1.50 ENSDART00000164915
scinla
scinderin like a
chr7_-_40713381 1.49 ENSDART00000031700
en2a
engrailed homeobox 2a
chr23_+_22051774 1.49 ENSDART00000145172
eif4g3b
eukaryotic translation initiation factor 4 gamma, 3b
chr6_-_12079553 1.48 ENSDART00000157058
si:dkey-276j7.1
si:dkey-276j7.1
chr17_+_16557246 1.48 ENSDART00000015729
ENSDART00000136874
foxn3
forkhead box N3
chr15_-_24934442 1.46 ENSDART00000127047
tusc5a
tumor suppressor candidate 5a
chr19_+_3925188 1.46

chr2_-_44429891 1.46 ENSDART00000163040
ENSDART00000056372
ENSDART00000109251
ENSDART00000166923
ENSDART00000132682
mpz
myelin protein zero
chr20_+_18803167 1.46 ENSDART00000019476
eif5
eukaryotic translation initiation factor 5
chr4_-_25080470 1.46 ENSDART00000179640
gata3
GATA binding protein 3
chr8_-_38308535 1.45

chr3_+_55779906 1.45

chr16_-_22947908 1.45 ENSDART00000133910
shc1
SHC (Src homology 2 domain containing) transforming protein 1
chr22_-_14247636 1.44

chr8_-_23744125 1.42 ENSDART00000141871
INAVA
innate immunity activator
chr9_-_306569 1.41 ENSDART00000166059
si:ch211-166e11.5
si:ch211-166e11.5
chr2_+_23038657 1.41 ENSDART00000089012
kif1ab
kinesin family member 1Ab
chr9_-_695593 1.41 ENSDART00000115030
dip2a
disco-interacting protein 2 homolog A
chr6_+_48156180 1.40 ENSDART00000019706
phc2b
polyhomeotic homolog 2b (Drosophila)
chr13_-_10128903 1.39 ENSDART00000080808
six3a
SIX homeobox 3a
chr13_+_10100146 1.38 ENSDART00000080805
six2a
SIX homeobox 2a
chr20_-_3970778 1.38 ENSDART00000178724
ENSDART00000178565
TRIM67
tripartite motif containing 67
chr18_+_22120282 1.38 ENSDART00000147230
zgc:158868
zgc:158868
chr21_-_2143830 1.37

chr14_+_6639864 1.36 ENSDART00000061001
gnb2l1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
chr22_-_14247765 1.35

chr5_-_31845561 1.35 ENSDART00000157295
ENSDART00000159522
ncs1a
neuronal calcium sensor 1a
chr1_-_57842604 1.33

chr23_-_6707246 1.32 ENSDART00000023793
mipb
major intrinsic protein of lens fiber b
chr16_+_11833310 1.31 ENSDART00000060266
ceacam1
carcinoembryonic antigen-related cell adhesion molecule 1
chr13_-_10128836 1.31 ENSDART00000080808
six3a
SIX homeobox 3a
chr21_-_3548719 1.31 ENSDART00000137844
atp8b1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr7_+_55883471 1.31 ENSDART00000073594
ankrd11
ankyrin repeat domain 11
chr1_+_14451504 1.31 ENSDART00000111475
pcdh7a
protocadherin 7a
chr16_+_25425398 1.28

chr18_-_41384938 1.28 ENSDART00000098673
ptx3a
pentraxin 3, long a
chr24_+_2322328 1.28 ENSDART00000132530
si:ch211-266d19.4
si:ch211-266d19.4
chr5_+_23093316 1.28 ENSDART00000006983
kat5a
K(lysine) acetyltransferase 5a
chr4_+_14361655 1.27 ENSDART00000007103
nuak1a
NUAK family, SNF1-like kinase, 1a
chr5_-_28025315 1.27 ENSDART00000131729
tnc
tenascin C
chr7_+_34394526 1.27

chr10_-_7954888 1.27 ENSDART00000139661
slc35e4
solute carrier family 35, member E4
chr9_-_22394674 1.27 ENSDART00000101869
crygm2d12
crystallin, gamma M2d12
chr24_+_25326286 1.26 ENSDART00000066625
smpx
small muscle protein, X-linked
chr23_-_24240728 1.26 ENSDART00000113598
arhgef19
Rho guanine nucleotide exchange factor (GEF) 19
chr1_-_41281418 1.25 ENSDART00000014678
adra1d
adrenoceptor alpha 1D
chr1_-_57329034 1.25 ENSDART00000160970
caspb
caspase b
chr11_+_23694891 1.25 ENSDART00000000486
cntn2
contactin 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
1.2 7.3 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
1.1 3.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
1.0 3.0 GO:0097702 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246) response to oscillatory fluid shear stress(GO:0097702) cellular response to oscillatory fluid shear stress(GO:0097704)
1.0 3.9 GO:0051122 lipoxygenase pathway(GO:0019372) linoleic acid metabolic process(GO:0043651) hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.9 2.7 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.9 2.6 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.8 3.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.8 7.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.8 4.0 GO:0048853 forebrain morphogenesis(GO:0048853)
0.7 2.2 GO:0070587 regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.7 2.2 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.7 3.3 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.6 1.9 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887) positive regulation of neuromuscular junction development(GO:1904398)
0.6 2.5 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.6 1.8 GO:0009957 epidermal cell fate specification(GO:0009957)
0.6 1.8 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.6 2.8 GO:0031646 positive regulation of neurological system process(GO:0031646)
0.5 1.6 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.5 1.6 GO:0002031 G-protein coupled receptor internalization(GO:0002031) regulation of protein binding(GO:0043393)
0.5 4.6 GO:0021754 facial nucleus development(GO:0021754)
0.5 2.5 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.5 3.2 GO:0070527 platelet aggregation(GO:0070527)
0.4 1.8 GO:0030043 actin filament fragmentation(GO:0030043)
0.4 2.6 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.4 2.5 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.4 1.3 GO:0003321 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.4 3.2 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.4 1.2 GO:1902024 serine transport(GO:0032329) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.4 1.6 GO:0033499 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.4 3.4 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.4 3.2 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.3 3.8 GO:0003348 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.3 1.0 GO:0042554 superoxide anion generation(GO:0042554)
0.3 2.3 GO:0031641 regulation of myelination(GO:0031641)
0.3 2.8 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.3 1.3 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.3 1.2 GO:0035776 pronephric proximal tubule development(GO:0035776)
0.3 2.4 GO:0033700 phospholipid efflux(GO:0033700)
0.3 1.8 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.3 0.9 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.3 1.8 GO:1900024 regulation of substrate adhesion-dependent cell spreading(GO:1900024)
0.3 2.6 GO:0048937 lateral line nerve glial cell differentiation(GO:0048895) myelination of lateral line nerve axons(GO:0048897) posterior lateral line nerve glial cell differentiation(GO:0048931) myelination of posterior lateral line nerve axons(GO:0048932) lateral line nerve glial cell development(GO:0048937) lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048938) posterior lateral line nerve glial cell development(GO:0048941) posterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048942)
0.3 1.5 GO:0045582 positive regulation of T cell differentiation(GO:0045582)
0.3 0.9 GO:0042908 xenobiotic transport(GO:0042908)
0.3 1.1 GO:0021523 somatic motor neuron differentiation(GO:0021523) cell-cell signaling involved in cell fate commitment(GO:0045168)
0.3 5.1 GO:0071711 basement membrane organization(GO:0071711)
0.3 4.7 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.3 1.6 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.3 1.1 GO:1901998 toxin transport(GO:1901998)
0.3 4.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.3 2.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.3 2.6 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.3 1.3 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379) cellular response to fatty acid(GO:0071398)
0.2 2.7 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.2 2.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.2 1.6 GO:0034653 diterpenoid catabolic process(GO:0016103) terpenoid catabolic process(GO:0016115) retinoic acid catabolic process(GO:0034653)
0.2 0.8 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 0.8 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.2 3.2 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.2 2.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 2.2 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.2 5.2 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.2 2.1 GO:0021884 forebrain neuron development(GO:0021884)
0.2 0.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 3.7 GO:0010508 positive regulation of autophagy(GO:0010508)
0.2 0.7 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929) response to cAMP(GO:0051591) cellular response to cAMP(GO:0071320) negative regulation of synaptic vesicle transport(GO:1902804) negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 0.5 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 2.9 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 2.8 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 2.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.0 GO:0006735 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 3.1 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 2.4 GO:0032526 response to retinoic acid(GO:0032526)
0.1 4.4 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.1 1.0 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 1.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.8 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.1 1.6 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 1.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 5.3 GO:0001570 vasculogenesis(GO:0001570)
0.1 0.8 GO:0007584 response to nutrient(GO:0007584)
0.1 0.6 GO:0009180 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.1 1.2 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.1 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.1 0.9 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 0.5 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.0 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.9 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 2.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 1.5 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 2.9 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.3 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.3 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.1 3.2 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.1 1.3 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 0.2 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.1 0.9 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.1 0.6 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.5 GO:0021602 cranial nerve morphogenesis(GO:0021602)
0.1 1.3 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0071684 hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 1.3 GO:0001843 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 4.7 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 1.2 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 3.4 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.7 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.3 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.0 1.3 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.0 0.8 GO:0032506 cytokinetic process(GO:0032506)
0.0 0.7 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 0.6 GO:0051014 actin filament severing(GO:0051014)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.5 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.7 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 1.3 GO:0030166 proteoglycan biosynthetic process(GO:0030166)
0.0 3.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 0.8 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.5 GO:0006813 potassium ion transport(GO:0006813)
0.0 0.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.6 GO:0033339 pectoral fin development(GO:0033339)
0.0 0.1 GO:0070572 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.1 GO:0032869 cellular response to insulin stimulus(GO:0032869)
0.0 1.9 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.9 GO:0007601 visual perception(GO:0007601)
0.0 0.6 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.3 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.7 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 1.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.6 GO:0022904 respiratory electron transport chain(GO:0022904)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.4 GO:0098644 complex of collagen trimers(GO:0098644)
0.9 4.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.4 3.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.3 1.0 GO:0043020 NADPH oxidase complex(GO:0043020)
0.3 1.3 GO:0061702 inflammasome complex(GO:0061702)
0.3 1.3 GO:0043034 costamere(GO:0043034)
0.2 1.0 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 3.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 1.3 GO:0016234 inclusion body(GO:0016234)
0.2 2.3 GO:0030056 hemidesmosome(GO:0030056)
0.2 1.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.2 2.1 GO:0045180 basal cortex(GO:0045180)
0.1 1.0 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 1.0 GO:0097651 phosphatidylinositol 3-kinase complex, class IB(GO:0005944) phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.1 0.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 1.5 GO:0043209 myelin sheath(GO:0043209)
0.1 3.0 GO:0008305 integrin complex(GO:0008305)
0.1 2.4 GO:0035102 PRC1 complex(GO:0035102)
0.1 5.0 GO:0005581 collagen trimer(GO:0005581)
0.1 4.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.6 GO:0002102 podosome(GO:0002102)
0.1 1.3 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 0.9 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.2 GO:0034457 Mpp10 complex(GO:0034457)
0.1 0.3 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 2.8 GO:0022626 cytosolic large ribosomal subunit(GO:0022625) cytosolic ribosome(GO:0022626)
0.1 9.1 GO:0009986 cell surface(GO:0009986)
0.0 0.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 3.0 GO:0031201 SNARE complex(GO:0031201)
0.0 1.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 22.2 GO:0005615 extracellular space(GO:0005615)
0.0 0.5 GO:0030904 retromer complex(GO:0030904)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.5 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.1 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 2.1 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.8 GO:0005902 microvillus(GO:0005902)
0.0 4.0 GO:0030424 axon(GO:0030424)
0.0 1.3 GO:0042641 actomyosin(GO:0042641)
0.0 3.8 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.7 GO:0030018 Z disc(GO:0030018)
0.0 0.4 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.6 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.4 GO:0044420 extracellular matrix component(GO:0044420)
0.0 3.9 GO:0005576 extracellular region(GO:0005576)
0.0 0.8 GO:0005882 intermediate filament(GO:0005882)
0.0 2.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.1 GO:0012506 vesicle membrane(GO:0012506)
0.0 0.5 GO:0005643 nuclear pore(GO:0005643)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 6.6 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
1.1 3.2 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.7 2.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.7 2.0 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.7 3.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.6 1.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.6 2.9 GO:0034632 retinol transporter activity(GO:0034632)
0.5 3.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 2.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.4 4.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.4 2.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.4 4.9 GO:0005272 sodium channel activity(GO:0005272)
0.4 1.7 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.4 1.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.4 2.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.4 3.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.4 7.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.4 3.8 GO:0005113 patched binding(GO:0005113)
0.4 1.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.4 4.7 GO:0001968 fibronectin binding(GO:0001968)
0.4 3.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 2.8 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.3 8.8 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.3 1.3 GO:0004936 alpha-adrenergic receptor activity(GO:0004936) alpha1-adrenergic receptor activity(GO:0004937)
0.3 1.8 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.3 1.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.3 3.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.3 1.6 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.3 1.3 GO:0015250 water channel activity(GO:0015250)
0.2 2.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.9 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 0.7 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.2 0.6 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.2 1.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.2 2.3 GO:0030506 ankyrin binding(GO:0030506)
0.2 2.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.2 1.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.2 1.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 1.5 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.2 2.7 GO:0005003 ephrin receptor activity(GO:0005003)
0.2 0.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 3.9 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 9.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 4.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.2 1.6 GO:0070569 uridylyltransferase activity(GO:0070569)
0.1 1.6 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.0 GO:0003872 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.1 1.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 1.0 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.8 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.1 4.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 1.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 3.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.5 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 0.9 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.9 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.1 2.9 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.1 3.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 2.4 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 0.5 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 3.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.1 GO:0005112 Notch binding(GO:0005112) PDZ domain binding(GO:0030165)
0.1 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.1 2.7 GO:0008201 heparin binding(GO:0008201)
0.1 3.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 5.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 4.8 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:1990939 ATP-dependent microtubule motor activity(GO:1990939)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 0.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 6.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.7 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0034595 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.0 0.4 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.2 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 1.3 GO:0015297 antiporter activity(GO:0015297)
0.0 0.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 1.2 GO:0019838 growth factor binding(GO:0019838)
0.0 2.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 31.7 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0 0.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 9.4 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.1 GO:0019956 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 1.5 GO:0020037 heme binding(GO:0020037)
0.0 2.3 GO:0042393 histone binding(GO:0042393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.4 8.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.3 7.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 4.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 2.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 1.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.8 PID IGF1 PATHWAY IGF1 pathway
0.1 1.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 2.6 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 3.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 1.0 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 0.4 PID BMP PATHWAY BMP receptor signaling
0.1 2.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 5.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 2.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 2.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.5 PID EPO PATHWAY EPO signaling pathway
0.0 1.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 1.0 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 2.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 8.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.4 1.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.3 2.8 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.3 1.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 2.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 1.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 2.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 2.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.2 6.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 3.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 5.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 0.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.3 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 2.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 4.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.1 1.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 0.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 2.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 2.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.3 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.9 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.0 0.9 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.5 REACTOME TRANSLATION Genes involved in Translation
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.6 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation