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DANIO-CODE

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Results for rxrab

Z-value: 1.21

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Transcription factors associated with rxrab

Gene Symbol Gene ID Gene Info
rxrab
ENSDARG00000035127 retinoid x receptor, alpha b

Activity profile of rxrab motif

Sorted Z-values of rxrab motif

Network of associatons between targets according to the STRING database.

First level regulatory network of rxrab

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr8_+_933677 6.07 ENSDART00000149528
fabp1b.1
fatty acid binding protein 1b, tandem duplicate 1
chr1_+_25157675 5.05 ENSDART00000136984
fabp2
fatty acid binding protein 2, intestinal
chr22_-_17570306 4.57 ENSDART00000139361
gpx4a
glutathione peroxidase 4a
chr12_-_5085227 4.33 ENSDART00000160729
rbp4
retinol binding protein 4, plasma
chr8_+_31426328 3.80 ENSDART00000135101
sepp1a
selenoprotein P, plasma, 1a
chr17_+_443558 3.73 ENSDART00000171386
zgc:194887
zgc:194887
chr3_-_31672763 3.37 ENSDART00000028270
gfap
glial fibrillary acidic protein
chr25_+_5162045 3.12 ENSDART00000169540
ENSDARG00000101164
ENSDARG00000101164
chr18_-_17426513 2.93 ENSDART00000150077
ces2
carboxylesterase 2 (intestine, liver)
KN149726v1_+_1094 2.81

chr2_-_43110857 2.74 ENSDART00000098303
oc90
otoconin 90
chr5_-_36237656 2.70 ENSDART00000032481
ckma
creatine kinase, muscle a
chr23_+_44817648 2.67 ENSDART00000143688
dlg4b
discs, large homolog 4b (Drosophila)
chr25_+_21732255 2.65 ENSDART00000027393
ckmt1
creatine kinase, mitochondrial 1
chr13_+_28689749 2.63 ENSDART00000101653
CU639469.1
ENSDARG00000062790
chr10_-_44180588 2.63 ENSDART00000145404
crybb1
crystallin, beta B1
chr5_+_8415025 2.59 ENSDART00000046440
agpat9l
1-acylglycerol-3-phosphate O-acyltransferase 9, like
chr5_+_40722565 2.59 ENSDART00000097546
arid3c
AT rich interactive domain 3C (BRIGHT-like)
chr11_-_35501227 2.53 ENSDART00000026017
bhlhe40
basic helix-loop-helix family, member e40
chr13_-_37001997 2.51 ENSDART00000135510
syne2b
spectrin repeat containing, nuclear envelope 2b
chr16_-_24697750 2.50 ENSDART00000163305
fxyd6l
FXYD domain containing ion transport regulator 6 like
chr3_+_39425125 2.47 ENSDART00000146867
aldoaa
aldolase a, fructose-bisphosphate, a
chr16_-_39181608 2.43 ENSDART00000075517
gdf6a
growth differentiation factor 6a
chr6_+_59788008 2.43

chr7_+_38626646 2.39 ENSDART00000172251
ENSDART00000164019
creb3l1
cAMP responsive element binding protein 3-like 1
chr16_+_42925950 2.36 ENSDART00000159730
ENSDART00000014956
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr12_+_27370834 2.31 ENSDART00000105661
meox1
mesenchyme homeobox 1
chr5_-_1325831 2.29

chr14_-_49115338 2.29 ENSDART00000056712
etfdh
electron-transferring-flavoprotein dehydrogenase
chr25_+_35797357 2.27 ENSDART00000152449
CR354435.1
ENSDARG00000039547
chr4_-_16461748 2.24 ENSDART00000128835
wu:fc23c09
wu:fc23c09
chr19_-_19290260 2.19

chr17_+_12254292 2.16 ENSDART00000160722
khk
ketohexokinase
chr21_+_20734431 2.14 ENSDART00000079732
oxct1b
3-oxoacid CoA transferase 1b
chr23_+_27985224 2.13 ENSDART00000171859
ENSDARG00000100606
ENSDARG00000100606
chr16_+_24697776 2.13

chr19_+_41274734 2.09 ENSDART00000126470
zgc:85777
zgc:85777
chr21_-_18969970 1.96 ENSDART00000080269
pgam2
phosphoglycerate mutase 2 (muscle)
chr16_-_29779166 1.94 ENSDART00000067854
tnfaip8l2b
tumor necrosis factor, alpha-induced protein 8-like 2b
chr6_-_39315024 1.94 ENSDART00000012644
krt4
keratin 4
chr6_-_30876091 1.93 ENSDART00000155330
pde4ba
phosphodiesterase 4B, cAMP-specific a
chr14_-_48951428 1.93 ENSDART00000157785
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr11_+_24720057 1.90 ENSDART00000145647
sulf2a
sulfatase 2a
chr12_+_27032862 1.90

chr9_+_33167554 1.87 ENSDART00000007630
nhlh2
nescient helix loop helix 2
chr15_+_19902697 1.84 ENSDART00000101204
alcamb
activated leukocyte cell adhesion molecule b
chr16_-_32022177 1.84 ENSDART00000139664
styk1
serine/threonine/tyrosine kinase 1
chr14_+_35906366 1.84 ENSDART00000105602
elovl6
ELOVL fatty acid elongase 6
chr4_-_2615160 1.84 ENSDART00000140760
e2f7
E2F transcription factor 7
chr20_+_30894667 1.82 ENSDART00000145066
nhsl1b
NHS-like 1b
chr22_+_38276148 1.82 ENSDART00000104504
si:ch211-284e20.8
si:ch211-284e20.8
chr5_+_37053530 1.76 ENSDART00000161051
sptbn2
spectrin, beta, non-erythrocytic 2
chr12_+_31558667 1.74 ENSDART00000152971
dnmbp
dynamin binding protein
chr5_-_64315770 1.72 ENSDART00000169287
zgc:110283
zgc:110283
chr25_+_4490129 1.71

chr2_+_53253623 1.70 ENSDART00000121980
creb3l3b
cAMP responsive element binding protein 3-like 3b
chr11_-_18166056 1.64 ENSDART00000155752
sfmbt1
Scm-like with four mbt domains 1
chr19_+_32579358 1.63 ENSDART00000021798
fabp11a
fatty acid binding protein 11a
chr25_+_15551474 1.62 ENSDART00000137375
spon1b
spondin 1b
chr20_+_13279404 1.62 ENSDART00000025644
ppp2r5a
protein phosphatase 2, regulatory subunit B', alpha isoform
chr3_-_56474209 1.58 ENSDART00000156398
si:ch211-189a21.1
si:ch211-189a21.1
chr9_-_1969197 1.57 ENSDART00000080608
hoxd10a
homeobox D10a
chr14_+_6122948 1.56 ENSDART00000149783
ENSDART00000148461
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr3_-_24989269 1.56 ENSDART00000154724
chadla
chondroadherin-like a
chr10_+_5693933 1.53 ENSDART00000159769
pam
peptidylglycine alpha-amidating monooxygenase
chr11_+_11217547 1.51 ENSDART00000087105
myom2a
myomesin 2a
chr2_+_48448974 1.49 ENSDART00000023040
hes6
hes family bHLH transcription factor 6
chr21_+_25199691 1.47 ENSDART00000168140
ENSDART00000112783
tmem45b
transmembrane protein 45B
chr7_+_31567166 1.45 ENSDART00000099785
ENSDART00000122506
mybpc3
myosin binding protein C, cardiac
chr3_-_18642744 1.45 ENSDART00000134208
hagh
hydroxyacylglutathione hydrolase
chr12_-_31342432 1.44 ENSDART00000148603
acsl5
acyl-CoA synthetase long-chain family member 5
chr2_-_39052185 1.44 ENSDART00000048838
rbp2b
retinol binding protein 2b, cellular
chr8_-_12171624 1.32 ENSDART00000132824
dab2ipa
DAB2 interacting protein a
chr23_+_32409339 1.31 ENSDART00000149698
slc39a5
solute carrier family 39 (zinc transporter), member 5
chr3_-_45420882 1.30 ENSDART00000161507
zgc:153426
zgc:153426
chr5_+_18827478 1.30 ENSDART00000089078
acacb
acetyl-CoA carboxylase beta
chr25_+_30701751 1.29

chr15_-_20297270 1.23 ENSDART00000123910
ppp1r14ab
protein phosphatase 1, regulatory (inhibitor) subunit 14Ab
chr20_+_15119519 1.23 ENSDART00000039345
myoc
myocilin
chr12_-_34612821 1.23 ENSDART00000153272
bahcc1b
BAH domain and coiled-coil containing 1b
chr9_-_41982635 1.22 ENSDART00000144573
obsl1b
obscurin-like 1b
chr11_+_30482530 1.22 ENSDART00000103270
slc22a7a
solute carrier family 22 (organic anion transporter), member 7a
chr17_+_51816782 1.22 ENSDART00000159072
flvcr2a
feline leukemia virus subgroup C cellular receptor family, member 2a
chr23_+_27141681 1.21 ENSDART00000054238
mipa
major intrinsic protein of lens fiber a
chr7_-_31170266 1.21 ENSDART00000075398
cilp
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr9_-_22347397 1.19 ENSDART00000146188
crygm2d16
crystallin, gamma M2d16
chr23_+_44951868 1.19

chr5_-_29891016 1.18 ENSDART00000138464
phldb1a
pleckstrin homology-like domain, family B, member 1a
chr15_+_3296905 1.18 ENSDART00000171723
foxo1a
forkhead box O1 a
chr19_-_20508993 1.17 ENSDART00000129917
mpp6b
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr6_+_60060297 1.16 ENSDART00000178621
pck1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr23_-_624534 1.16 ENSDART00000132175
nadl1.1
neural adhesion molecule L1.1
chr7_-_23775835 1.15 ENSDART00000144616
dhrs4
dehydrogenase/reductase (SDR family) member 4
chr25_-_34608926 1.12 ENSDART00000130395
hist1h4l
histone 1, H4, like
chr16_-_22218191 1.11 ENSDART00000140175
si:dkey-71b5.3
si:dkey-71b5.3
chr20_-_53162473 1.10 ENSDART00000164460
gata4
GATA binding protein 4
chr21_-_12958161 1.09 ENSDART00000133517
MYORG
si:dkey-228b2.5
chr12_-_34612758 1.09 ENSDART00000153272
bahcc1b
BAH domain and coiled-coil containing 1b
chr23_+_42370612 1.05 ENSDART00000161812
cyp2aa9
cytochrome P450, family 2, subfamily AA, polypeptide 9
chr10_-_30016761 1.04 ENSDART00000078800
lim2.1
lens intrinsic membrane protein 2.1
chr19_+_32570656 1.04 ENSDART00000005255
mrpl53
mitochondrial ribosomal protein L53
chr21_-_45852590 1.01 ENSDART00000169816
galnt10
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10)
chr20_+_15119754 1.01 ENSDART00000039345
myoc
myocilin
chr22_-_26971466 1.01 ENSDART00000087202
ENSDARG00000061256
ENSDARG00000061256
chr5_-_63031745 0.99

chr15_-_47264693 0.98

chr5_-_21520111 0.98

chr10_+_31358236 0.98 ENSDART00000145562
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr17_-_16079935 0.97

chr16_+_55167489 0.97 ENSDART00000149795
nr0b2a
nuclear receptor subfamily 0, group B, member 2a
chr21_+_13063614 0.95

chr22_-_20101177 0.95 ENSDART00000138688
creb3l3a
cAMP responsive element binding protein 3-like 3a
chr19_+_43525255 0.94

chr19_+_11061965 0.94 ENSDART00000142975
si:ch1073-70f20.1
si:ch1073-70f20.1
chr1_+_50348973 0.93

chr5_+_26804344 0.93 ENSDART00000121886
ENSDART00000005025
hdr
hematopoietic death receptor
chr21_+_15737517 0.93 ENSDART00000151161
ENSDARG00000044755
ENSDARG00000044755
chr19_+_43525673 0.92

chr23_-_3814291 0.91

chr9_+_1968455 0.90

chr16_-_8711133 0.89

chr10_-_17484971 0.88

chr18_+_17622557 0.86 ENSDART00000046891
cetp
cholesteryl ester transfer protein, plasma
chr15_-_16948863 0.85 ENSDART00000062135
ENSDARG00000042379
ENSDARG00000042379
chr4_+_25637474 0.85 ENSDART00000066942
ENSDART00000041965
acot15
acyl-CoA thioesterase 15
chr20_+_25567046 0.84 ENSDART00000153071
pfas
phosphoribosylformylglycinamidine synthase
chr14_-_27754549 0.84 ENSDART00000135337
zgc:64189
zgc:64189
chr19_+_41628053 0.84

chr2_+_46179589 0.82 ENSDART00000125971
gpc1b
glypican 1b
chr20_-_48773402 0.82 ENSDART00000161769
mgst3a
microsomal glutathione S-transferase 3a
chr14_-_32449229 0.82 ENSDART00000172996
AL590151.1
ENSDARG00000053570
chr8_+_25984588 0.81

chr13_-_40600924 0.81 ENSDART00000099847
ENSDART00000057046
st3gal7
ST3 beta-galactoside alpha-2,3-sialyltransferase 7
chr1_+_11485480 0.80 ENSDART00000132560
stra6l
STRA6-like
chr14_-_9216303 0.79 ENSDART00000054689
atoh8
atonal bHLH transcription factor 8
chr3_+_12633028 0.79 ENSDART00000168382
cyp2k8
cytochrome P450, family 2, subfamily K, polypeptide 8
chr19_-_22914312 0.78

chr5_+_37600633 0.78 ENSDART00000100769
hsd20b2
hydroxysteroid (20-beta) dehydrogenase 2
chr12_-_34621359 0.76

chr25_+_3884499 0.75 ENSDART00000104926
ENSDARG00000058108
ENSDARG00000058108
chr17_-_24666272 0.75 ENSDART00000105457
morn2
MORN repeat containing 2
chr9_+_28301359 0.75

chr16_-_1479139 0.73 ENSDART00000036348
sim1a
single-minded family bHLH transcription factor 1a
chr18_+_12687027 0.73 ENSDART00000144246
tbxas1
thromboxane A synthase 1 (platelet)
chr20_-_49307929 0.73 ENSDART00000057700
naa20
N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr4_+_2725218 0.73 ENSDART00000007638
bcap29
B-cell receptor-associated protein 29
chr16_+_46239355 0.71 ENSDART00000168145
bola1
bolA family member 1
chr1_+_23093114 0.70

chr3_+_33629940 0.70 ENSDART00000169337
ier2a
immediate early response 2a
chr22_-_17570275 0.68 ENSDART00000099056
gpx4a
glutathione peroxidase 4a
chr25_+_21919595 0.67 ENSDART00000156517
ENSDARG00000062199
ENSDARG00000062199
chr7_+_20377678 0.66 ENSDART00000173710
si:dkey-19b23.15
si:dkey-19b23.15
chr19_+_4142216 0.66

chr1_-_49274993 0.66 ENSDART00000050603
hadh
hydroxyacyl-CoA dehydrogenase
chr15_-_47264619 0.66

chr2_-_49060868 0.65

chr13_-_44492897 0.65

chr6_-_43892838 0.65 ENSDART00000148646
ENSDART00000148909
foxp1b
forkhead box P1b
chr20_+_13279491 0.65 ENSDART00000025644
ppp2r5a
protein phosphatase 2, regulatory subunit B', alpha isoform
chr11_-_30971376 0.65 ENSDART00000170700
nacc1b
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing b
chr15_-_1880456 0.63 ENSDART00000102410
taf15
TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_-_30005139 0.63 ENSDART00000146968
cnpy1
canopy1
chr8_+_30654835 0.63 ENSDART00000138750
adora2aa
adenosine A2a receptor a
chr21_-_4086050 0.62 ENSDART00000099389
dnlz
DNL-type zinc finger
chr7_-_51186389 0.61 ENSDART00000174328
arhgap6
Rho GTPase activating protein 6
chr20_+_49273889 0.61 ENSDART00000166051
ENSDART00000112689
crnkl1
crooked neck pre-mRNA splicing factor 1
chr22_-_15694002 0.61 ENSDART00000105692
mrpl54
mitochondrial ribosomal protein L54
chr3_+_49166063 0.60 ENSDART00000156347
epn3a
epsin 3a
chr14_-_6939857 0.59 ENSDART00000108796
stox2b
storkhead box 2b
chr16_+_5470419 0.59

chr17_+_43605118 0.59 ENSDART00000156271
cfap99
cilia and flagella associated protein 99
chr13_-_25068717 0.58 ENSDART00000057605
adka
adenosine kinase a
chr12_+_27035744 0.57 ENSDART00000025966
hoxb6b
homeobox B6b
chr2_-_6351592 0.57

chr18_-_48498261 0.56 ENSDART00000146346
kcnj1a.6
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr18_+_16755239 0.56 ENSDART00000133490
lyve1b
lymphatic vessel endothelial hyaluronic receptor 1b
chr2_+_3992842 0.55 ENSDART00000103596
ENSDART00000161880
npc1
Niemann-Pick disease, type C1
chr19_-_22914516 0.55

chr22_+_18218979 0.55

chr1_-_51086211 0.54 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
chr16_+_28667291 0.54 ENSDART00000018235
crot
carnitine O-octanoyltransferase
chr10_-_6453139 0.53 ENSDART00000168549
ca9
carbonic anhydrase IX
chr11_+_30035395 0.53 ENSDART00000122756
si:dkey-163f14.6
si:dkey-163f14.6
chr2_+_23600656 0.53

chr21_+_15737192 0.53 ENSDART00000151161
ENSDARG00000044755
ENSDARG00000044755
chr12_+_29994880 0.51 ENSDART00000042572
ENSDART00000153025
ablim1b
actin binding LIM protein 1b
chr21_-_34809442 0.51 ENSDART00000029708
zgc:56585
zgc:56585
chr23_+_36241656 0.50 ENSDART00000011201
copz1
coatomer protein complex, subunit zeta 1
chr5_-_47519273 0.50

chr13_-_37002066 0.49 ENSDART00000135510
syne2b
spectrin repeat containing, nuclear envelope 2b
chr18_+_18465885 0.49 ENSDART00000165079
siah1
siah E3 ubiquitin protein ligase 1
chr15_-_29900 0.49

chr13_+_45843396 0.48 ENSDART00000005195
ENSDART00000074547
bsdc1
BSD domain containing 1
chr24_-_21768269 0.48 ENSDART00000081178
c1qtnf9
C1q and TNF related 9
chr15_+_494813 0.48 ENSDART00000155682
nipsnap2
nipsnap homolog 2
chr6_+_28127514 0.47

chr2_-_10602948 0.47 ENSDART00000016369
wls
wntless Wnt ligand secretion mediator
chr8_+_7974156 0.47

chr14_-_48951396 0.45 ENSDART00000157785
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr1_+_43881022 0.45 ENSDART00000003022
ENSDART00000137980
med19b
mediator complex subunit 19b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578)
0.8 2.5 GO:0045475 locomotor rhythm(GO:0045475)
0.8 2.4 GO:0046552 blood vessel maturation(GO:0001955) retinal cone cell fate determination(GO:0042671) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate determination(GO:0043703) retinal cone cell fate commitment(GO:0046551) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.7 5.4 GO:0046314 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.6 5.1 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.6 1.8 GO:0032875 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.5 2.1 GO:0046950 cellular ketone body metabolic process(GO:0046950) ketone body metabolic process(GO:1902224)
0.5 1.4 GO:0010747 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) regulation of organic acid transport(GO:0032890) positive regulation of organic acid transport(GO:0032892) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transport(GO:1903793) regulation of anion transmembrane transport(GO:1903959) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.4 1.3 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.4 1.2 GO:0097037 heme export(GO:0097037)
0.4 1.2 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.4 2.7 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.3 1.3 GO:0003210 cardiac atrium formation(GO:0003210)
0.3 2.3 GO:0061056 sclerotome development(GO:0061056)
0.3 2.2 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.3 1.2 GO:0019543 propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) glycerol biosynthetic process from pyruvate(GO:0046327) cellular response to dexamethasone stimulus(GO:0071549)
0.3 0.9 GO:0034372 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372) reverse cholesterol transport(GO:0043691) phospholipid homeostasis(GO:0055091)
0.3 1.8 GO:0021885 forebrain cell migration(GO:0021885)
0.2 1.0 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.2 1.9 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 2.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341)
0.2 2.2 GO:0001952 regulation of cell-matrix adhesion(GO:0001952)
0.2 1.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.2 1.9 GO:0048795 swim bladder morphogenesis(GO:0048795)
0.2 2.2 GO:0009746 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.2 1.5 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.2 1.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.2 0.6 GO:0098751 bone cell development(GO:0098751)
0.2 0.7 GO:0035776 pronephric proximal tubule development(GO:0035776)
0.2 0.7 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 1.5 GO:0046185 aldehyde catabolic process(GO:0046185)
0.2 1.2 GO:0006833 water transport(GO:0006833)
0.2 1.8 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.2 0.7 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.6 GO:0044209 AMP salvage(GO:0044209)
0.1 2.5 GO:0030388 thigmotaxis(GO:0001966) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.8 GO:0097475 motor neuron migration(GO:0097475)
0.1 5.0 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 0.5 GO:0061355 Wnt protein secretion(GO:0061355)
0.1 0.8 GO:0033555 multicellular organismal response to stress(GO:0033555)
0.1 2.1 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 2.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.6 GO:0061469 regulation of cell proliferation involved in tissue homeostasis(GO:0060784) regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.4 GO:0006751 glutathione catabolic process(GO:0006751) response to estradiol(GO:0032355)
0.1 9.7 GO:0033993 response to lipid(GO:0033993)
0.1 1.6 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.1 0.5 GO:0033700 phospholipid efflux(GO:0033700)
0.1 2.4 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.8 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.8 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 2.0 GO:0007520 myoblast fusion(GO:0007520)
0.1 1.0 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.1 0.4 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
0.1 3.8 GO:0007601 visual perception(GO:0007601)
0.1 2.9 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 1.0 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.4 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 3.8 GO:0006979 response to oxidative stress(GO:0006979)
0.0 1.8 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.0 1.1 GO:0030835 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) actin filament capping(GO:0051693)
0.0 0.5 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.2 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.0 0.3 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.0 0.4 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0043545 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0 0.4 GO:0061512 protein localization to cilium(GO:0061512)
0.0 1.3 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.4 GO:0030073 insulin secretion(GO:0030073)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107) potassium ion import across plasma membrane(GO:1990573)
0.0 1.2 GO:0021782 glial cell development(GO:0021782)
0.0 0.9 GO:0031647 regulation of protein stability(GO:0031647)
0.0 1.5 GO:0006936 muscle contraction(GO:0006936)
0.0 1.3 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.8 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.5 GO:0007416 synapse assembly(GO:0007416)
0.0 0.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0008091 spectrin(GO:0008091)
0.2 2.7 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 1.5 GO:0031430 M band(GO:0031430)
0.1 0.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 1.9 GO:0045095 keratin filament(GO:0045095)
0.1 2.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.2 GO:0045180 basal cortex(GO:0045180)
0.1 0.4 GO:0032420 stereocilium(GO:0032420)
0.1 0.7 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.1 2.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 2.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.6 GO:0000974 Prp19 complex(GO:0000974) U2-type catalytic step 2 spliceosome(GO:0071007)
0.1 3.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.8 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 3.4 GO:0005795 Golgi stack(GO:0005795)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 2.2 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 1.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 1.1 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 3.8 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.6 GO:0030125 clathrin vesicle coat(GO:0030125)
0.0 0.0 GO:1902737 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.0 16.6 GO:0005576 extracellular region(GO:0005576)
0.0 1.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.6 GO:0030424 axon(GO:0030424)
0.0 1.1 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
1.0 11.1 GO:0005504 fatty acid binding(GO:0005504)
0.9 4.3 GO:0034632 retinol transporter activity(GO:0034632)
0.7 5.4 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.5 2.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.4 2.6 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.4 1.5 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) amidine-lyase activity(GO:0016842)
0.4 2.3 GO:0048039 ubiquinone binding(GO:0048039)
0.3 2.0 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.3 1.2 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.3 2.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 0.8 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.3 5.0 GO:0035497 cAMP response element binding(GO:0035497)
0.2 2.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.2 2.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.0 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.2 1.2 GO:0015250 water channel activity(GO:0015250)
0.2 0.6 GO:0004001 adenosine kinase activity(GO:0004001)
0.2 2.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.2 0.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2 1.8 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 0.5 GO:0016415 octanoyltransferase activity(GO:0016415)
0.2 4.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 1.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 0.7 GO:0019808 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.1 1.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 1.4 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 0.4 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.1 1.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.1 2.3 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 1.2 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.6 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 1.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.8 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.5 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 1.8 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.1 1.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.3 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 2.2 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 1.0 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.8 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.9 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 1.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 2.4 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 6.7 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 3.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 2.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID CERAMIDE PATHWAY Ceramide signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.3 2.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.3 1.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 3.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 3.4 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 0.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 0.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.8 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 2.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.3 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 2.2 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates