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Results for scrt1a+scrt1b+scrt2

Z-value: 1.16

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Transcription factors associated with scrt1a+scrt1b+scrt2

Gene Symbol Gene ID Gene Info
scrt1b
ENSDARG00000040214 scratch family zinc finger 1b
scrt2
ENSDARG00000056175 scratch family zinc finger 2
scrt1a
ENSDARG00000100821 scratch family zinc finger 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
scrt2dr10_dc_chr8_+_28493742_284937550.801.9e-04Click!
scrt1adr10_dc_chr19_+_1626598_16266180.638.4e-03Click!
scrt1bdr10_dc_chr16_-_31230568_312305720.292.8e-01Click!

Activity profile of scrt1a+scrt1b+scrt2 motif

Sorted Z-values of scrt1a+scrt1b+scrt2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of scrt1a+scrt1b+scrt2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_-_32543497 5.06 ENSDART00000026635
nr2e1
nuclear receptor subfamily 2, group E, member 1
chr16_-_45258675 3.37 ENSDART00000158855
fxyd1
FXYD domain containing ion transport regulator 1 (phospholemman)
chr16_-_9978112 3.35 ENSDART00000149312
ncalda
neurocalcin delta a
chr2_-_30675594 3.32 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr9_-_34491458 3.32 ENSDART00000049805
ildr2
immunoglobulin-like domain containing receptor 2
chr16_+_29716279 3.19 ENSDART00000137153
tmod4
tropomodulin 4 (muscle)
chr16_-_39620777 3.09 ENSDART00000039832
tgfbr2b
transforming growth factor beta receptor 2b
chr2_-_23516930 2.82 ENSDART00000165355
prrx1a
paired related homeobox 1a
chr15_-_41288480 2.61 ENSDART00000155359
smco4
single-pass membrane protein with coiled-coil domains 4
chr16_+_5778398 2.39 ENSDART00000011166
ENSDART00000126445
zgc:158689
zgc:158689
chr20_+_22321303 2.37 ENSDART00000049204
kdr
kinase insert domain receptor (a type III receptor tyrosine kinase)
chr23_-_6588073 2.27 ENSDART00000092214
ENSDART00000138020
bmp7b
bone morphogenetic protein 7b
chr7_+_59445089 2.26 ENSDART00000175691
ENSDART00000179121
CR384075.1
ENSDARG00000108680
chr7_+_47014195 2.22 ENSDART00000114669
dpy19l3
dpy-19-like 3 (C. elegans)
chr4_+_8531280 2.20 ENSDART00000162065
wnt5b
wingless-type MMTV integration site family, member 5b
chr7_+_38626646 2.14 ENSDART00000172251
ENSDART00000164019
creb3l1
cAMP responsive element binding protein 3-like 1
chr11_+_36215554 2.13 ENSDART00000128245
ldlrad2
low density lipoprotein receptor class A domain containing 2
chr20_-_19646761 2.10

chr20_+_40247918 2.09 ENSDART00000121818
trdn
triadin
chr1_+_50835265 2.07 ENSDART00000162226
meis1a
Meis homeobox 1 a
chr9_+_44233139 2.04 ENSDART00000162406
itga4
integrin alpha 4
chr7_-_54407681 2.03 ENSDART00000162795
ccnd1
cyclin D1
chr24_-_34449257 1.93 ENSDART00000128690
agap3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr2_+_33057931 1.89

chr9_+_48717490 1.83 ENSDART00000163353
lrp2a
low density lipoprotein receptor-related protein 2a
chr7_-_29021031 1.82 ENSDART00000086753
dapk2a
death-associated protein kinase 2a
chr12_+_28739504 1.76 ENSDART00000152991
nfe2l1b
nuclear factor, erythroid 2-like 1b
chr5_-_65103730 1.72 ENSDART00000169616
notch1b
notch 1b
chr10_+_9716807 1.70 ENSDART00000064977
si:ch211-243g18.2
si:ch211-243g18.2
chr5_-_65103664 1.69 ENSDART00000130888
notch1b
notch 1b
chr25_-_13518274 1.66 ENSDART00000165510
fa2h
fatty acid 2-hydroxylase
chr15_+_5935952 1.65 ENSDART00000152520
ENSDART00000145827
sh3bgr
SH3 domain binding glutamate-rich protein
chr3_-_30027552 1.63 ENSDART00000103502
si:ch211-152f23.5
si:ch211-152f23.5
chr16_-_17164459 1.62 ENSDART00000178443
tnfrsf1a
tumor necrosis factor receptor superfamily, member 1a
chr16_+_5778650 1.57 ENSDART00000131575
zgc:158689
zgc:158689
chr7_-_54407461 1.55 ENSDART00000162795
ccnd1
cyclin D1
chr7_-_52283383 1.50 ENSDART00000165649
tcf12
transcription factor 12
chr19_+_31944725 1.47 ENSDART00000136289
tmem64
transmembrane protein 64
chr17_-_2513630 1.47 ENSDART00000135374
ptpn21
protein tyrosine phosphatase, non-receptor type 21
chr14_+_37206949 1.45

chr14_+_6117282 1.40 ENSDART00000051556
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr20_+_34608782 1.39 ENSDART00000061588
prrx1b
paired related homeobox 1b
chr20_-_52459338 1.38 ENSDART00000135463
rhpn1
rhophilin, Rho GTPase binding protein 1
chr21_+_41684338 1.32 ENSDART00000169511
ppp2r2bb
protein phosphatase 2, regulatory subunit B, beta b
chr1_+_6995893 1.28 ENSDART00000163488
en1b
engrailed homeobox 1b
chr7_-_41188744 1.27 ENSDART00000174087
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr3_+_37433008 1.26 ENSDART00000055225
wnt9b
wingless-type MMTV integration site family, member 9B
chr23_+_35984675 1.24 ENSDART00000053295
hoxc10a
homeobox C10a
chr25_+_3884499 1.24 ENSDART00000104926
ENSDARG00000058108
ENSDARG00000058108
chr23_-_18203680 1.23 ENSDART00000016976
nucks1b
nuclear casein kinase and cyclin-dependent kinase substrate 1b
chr16_+_11138924 1.22 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr13_+_25356121 1.19 ENSDART00000057689
bag3
BCL2-associated athanogene 3
chr21_-_11554253 1.16 ENSDART00000133443
cast
calpastatin
chr16_+_11138879 1.16 ENSDART00000091183
erfl3
Ets2 repressor factor like 3
chr21_+_7578326 1.16 ENSDART00000164883
CU655836.1
ENSDARG00000105204
chr5_+_26925238 1.14 ENSDART00000051491
sfrp1a
secreted frizzled-related protein 1a
chr13_+_25356184 1.12 ENSDART00000057689
bag3
BCL2-associated athanogene 3
chr13_+_32013916 1.10 ENSDART00000020270
osr1
odd-skipped related transciption factor 1
chr18_+_41323776 1.02 ENSDART00000048985
veph1
ventricular zone expressed PH domain-containing 1
chr13_+_13447540 1.01 ENSDART00000101673
foxi2
forkhead box I2
chr24_+_26922969 0.99

chr4_+_8531350 0.94 ENSDART00000162065
wnt5b
wingless-type MMTV integration site family, member 5b
chr17_+_34238628 0.93 ENSDART00000014306
mpp5a
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr8_+_7655655 0.92 ENSDART00000170184
fgd1
FYVE, RhoGEF and PH domain containing 1
chr2_-_53156364 0.92

chr24_+_25767893 0.90 ENSDART00000143099
map3k15
mitogen-activated protein kinase kinase kinase 15
chr7_+_22314304 0.90 ENSDART00000149144
chrnb1l
cholinergic receptor, nicotinic, beta 1 (muscle) like
chr2_-_23516991 0.84 ENSDART00000165355
prrx1a
paired related homeobox 1a
chr13_-_4204592 0.84 ENSDART00000122406
znf318
zinc finger protein 318
chr20_+_40248154 0.81 ENSDART00000121818
trdn
triadin
chr3_+_34716733 0.80 ENSDART00000055263
itga3a
integrin, alpha 3a
chr20_-_32543458 0.80 ENSDART00000026635
nr2e1
nuclear receptor subfamily 2, group E, member 1
chr6_-_34955205 0.80 ENSDART00000131610
serbp1a
SERPINE1 mRNA binding protein 1a
chr23_-_32231333 0.80 ENSDART00000000876
nr4a1
nuclear receptor subfamily 4, group A, member 1
chr17_-_52435859 0.80

chr5_+_26925392 0.77 ENSDART00000051491
sfrp1a
secreted frizzled-related protein 1a
chr22_-_12723704 0.75 ENSDART00000080741
plcd4a
phospholipase C, delta 4a
chr7_+_60874319 0.74 ENSDART00000110671
zgc:194930
zgc:194930
chr2_-_7560202 0.73 ENSDART00000164494
asip2b
agouti signaling protein, nonagouti homolog (mouse) 2b
chr25_+_29631901 0.71 ENSDART00000154849
ENSDARG00000029431
ENSDARG00000029431
chr22_-_23518719 0.69 ENSDART00000161253
crb1
crumbs family member 1, photoreceptor morphogenesis associated
chr25_-_28691412 0.67 ENSDART00000067066
parp6b
poly (ADP-ribose) polymerase family, member 6b
chr17_+_21270766 0.63

chr7_-_41188699 0.57 ENSDART00000150146
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr3_-_55774195 0.52 ENSDART00000113030
ENSDART00000160876
ENSDART00000168198
ENSDART00000161499
ENSDART00000157764
cep112
centrosomal protein 112
chr17_+_612173 0.52

chr14_-_47909935 0.52 ENSDART00000058789
qdpra
quinoid dihydropteridine reductase a
chr23_-_6442213 0.52 ENSDART00000112667
ppp1r12b
protein phosphatase 1, regulatory subunit 12B
chr11_+_36215760 0.52 ENSDART00000128245
ldlrad2
low density lipoprotein receptor class A domain containing 2
chr23_+_35984885 0.49 ENSDART00000130260
hoxc10a
homeobox C10a
chr24_+_12845250 0.49 ENSDART00000126842
flj11011l
hypothetical protein FLJ11011-like (H. sapiens)
chr10_-_41430693 0.48 ENSDART00000052971
ENSDART00000128156
rab11fip1b
RAB11 family interacting protein 1 (class I) b
chr21_+_29190291 0.45 ENSDART00000013641
adra1ba
adrenoceptor alpha 1Ba
chr4_+_16721264 0.44 ENSDART00000035899
pkp2
plakophilin 2
chr8_-_30415016 0.42

chr22_+_4947542 0.42 ENSDART00000150202
MYO9B
myosin IXB
chr4_-_21745163 0.42 ENSDART00000139962
pawr
PRKC, apoptosis, WT1, regulator
chr14_-_21854679 0.39 ENSDART00000115422
nudcd2
NudC domain containing 2
chr8_+_31812204 0.39 ENSDART00000077053
plcxd3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr2_-_23516868 0.36 ENSDART00000165355
prrx1a
paired related homeobox 1a
chr10_-_13438574 0.36 ENSDART00000030976
il11ra
interleukin 11 receptor, alpha
chr24_+_25767966 0.36 ENSDART00000143099
map3k15
mitogen-activated protein kinase kinase kinase 15
chr24_-_34449346 0.33 ENSDART00000128690
agap3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr6_-_34955083 0.32 ENSDART00000135425
serbp1a
SERPINE1 mRNA binding protein 1a
chr7_+_29969936 0.30 ENSDART00000109243
sema4bb
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr7_+_47013995 0.30 ENSDART00000114669
dpy19l3
dpy-19-like 3 (C. elegans)
chr4_+_16721069 0.29 ENSDART00000035899
pkp2
plakophilin 2
chr3_-_49010673 0.29 ENSDART00000109544
si:ch1073-100f3.2
si:ch1073-100f3.2
chr22_+_28854577 0.24 ENSDART00000129476
tp53bp2b
tumor protein p53 binding protein, 2b
chr7_-_20565207 0.24 ENSDART00000052977
cldn15a
claudin 15a
chr4_+_10367008 0.23 ENSDART00000138890
kcnd2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr21_-_4684440 0.21 ENSDART00000168930
notch1a
notch 1a
chr13_-_46535490 0.20

chr11_+_328781 0.14 ENSDART00000147426
pdrg1
p53 and DNA-damage regulated 1
chr6_-_52677210 0.14 ENSDART00000083830
sdc4
syndecan 4
chr14_-_49044809 0.13 ENSDART00000169300
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr16_-_24682800 0.12 ENSDART00000156407
ENSDART00000154072
si:dkey-56f14.4
si:dkey-56f14.4
chr8_+_10785326 0.10 ENSDART00000081341
mapk13
mitogen-activated protein kinase 13
chr6_+_27371540 0.09 ENSDART00000065238
crocc2
ciliary rootlet coiled-coil, rootletin family member 2
chr17_+_23442934 0.08 ENSDART00000112959
ankrd1a
ankyrin repeat domain 1a (cardiac muscle)
chr25_-_28630945 0.06 ENSDART00000165603
arid3b
AT rich interactive domain 3B (BRIGHT-like)
chr11_+_36215690 0.06 ENSDART00000128245
ldlrad2
low density lipoprotein receptor class A domain containing 2
chr12_-_13611954 0.04 ENSDART00000124638
ENSDART00000124364
stat5b
signal transducer and activator of transcription 5b
chr10_-_22942639 0.04 ENSDART00000131992
si:ch1073-143l10.2
si:ch1073-143l10.2
chr12_+_13704914 0.01 ENSDART00000152257
ppp1r16a
protein phosphatase 1, regulatory subunit 16A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
1.0 4.0 GO:0086019 atrial cardiac muscle cell action potential(GO:0086014) cell-cell signaling involved in cardiac conduction(GO:0086019) atrial cardiac muscle cell to AV node cell signaling(GO:0086026) cell communication involved in cardiac conduction(GO:0086065) atrial cardiac muscle cell to AV node cell communication(GO:0086066)
0.6 2.5 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.6 2.3 GO:0010660 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.5 3.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.5 2.6 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) mitotic G1 DNA damage checkpoint(GO:0031571) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.5 4.0 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.3 1.8 GO:0070293 renal absorption(GO:0070293)
0.3 2.7 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
0.3 3.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.3 1.1 GO:0035776 pronephric proximal tubule development(GO:0035776)
0.2 0.7 GO:0032369 negative regulation of lipid transport(GO:0032369) endocrine process(GO:0050886) positive regulation of feeding behavior(GO:2000253)
0.2 1.0 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.2 1.4 GO:0033700 phospholipid efflux(GO:0033700)
0.2 1.8 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.2 0.5 GO:0010460 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996) positive regulation of blood pressure by epinephrine-norepinephrine(GO:0003321) positive regulation of heart rate(GO:0010460)
0.1 1.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 1.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 1.2 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 1.3 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.7 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 0.5 GO:0006559 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 2.4 GO:0035924 cellular response to vascular endothelial growth factor stimulus(GO:0035924)
0.1 1.6 GO:0030593 neutrophil chemotaxis(GO:0030593)
0.1 2.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 0.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 0.3 GO:0071422 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.1 2.1 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 2.0 GO:0001946 lymphangiogenesis(GO:0001946)
0.1 1.2 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.4 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 1.2 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 3.1 GO:0071559 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.0 3.3 GO:0007492 endoderm development(GO:0007492)
0.0 0.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 1.8 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 8.2 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 2.1 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 1.5 GO:0001837 epithelial to mesenchymal transition(GO:0001837)
0.0 0.2 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 1.7 GO:0006633 fatty acid biosynthetic process(GO:0006633)
0.0 1.8 GO:0010942 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 1.0 GO:0042471 ear morphogenesis(GO:0042471)
0.0 0.8 GO:0071375 cellular response to peptide hormone stimulus(GO:0071375) cellular response to peptide(GO:1901653)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 1.8 GO:0071564 npBAF complex(GO:0071564)
0.1 0.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 3.2 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.1 2.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 2.3 GO:0008305 integrin complex(GO:0008305)
0.1 5.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 0.7 GO:0014704 intercalated disc(GO:0014704)
0.1 3.6 GO:0014069 postsynaptic density(GO:0014069)
0.1 2.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.3 GO:0030018 Z disc(GO:0030018)
0.0 1.7 GO:0005882 intermediate filament(GO:0005882)
0.0 3.7 GO:0043235 receptor complex(GO:0043235)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026) type I transforming growth factor beta receptor binding(GO:0034713)
0.3 1.6 GO:0005035 death receptor activity(GO:0005035)
0.3 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 2.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.3 2.3 GO:0070700 BMP receptor binding(GO:0070700)
0.2 2.4 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.2 1.4 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 3.2 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.0 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.2 2.3 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.7 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 4.4 GO:0005109 frizzled binding(GO:0005109)
0.1 2.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.5 GO:0004937 alpha-adrenergic receptor activity(GO:0004936) alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.5 GO:0070402 NADPH binding(GO:0070402)
0.1 1.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.8 GO:0042562 hormone binding(GO:0042562)
0.1 2.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 0.9 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 5.9 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 3.3 GO:0045296 cadherin binding(GO:0045296)
0.1 0.3 GO:0015131 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140) succinate transmembrane transporter activity(GO:0015141)
0.1 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.8 GO:0051020 GTPase binding(GO:0051020)
0.0 2.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 3.9 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 1.2 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.7 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.2 GO:0002039 p53 binding(GO:0002039)
0.0 1.7 GO:0020037 heme binding(GO:0020037)
0.0 0.2 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0019955 cytokine binding(GO:0019955)
0.0 1.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.5 1.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3 2.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 2.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 4.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.3 1.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.3 6.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 2.6 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 1.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels