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Results for shox2_uncx4.1_lhx2a_vsx1_shox
Z-value: 2.71
Motif logo
Transcription factors associated with shox2_uncx4.1_lhx2a_vsx1_shox
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
shox2
|
ENSDARG00000075713 | short stature homeobox 2 |
|
uncx4.1
|
ENSDARG00000037760 | Unc4.1 homeobox (C. elegans) |
|
lhx2a
|
ENSDARG00000037964 | LIM homeobox 2a |
|
vsx1
|
ENSDARG00000056292 | visual system homeobox 1 homolog, chx10-like |
|
shox
|
ENSDARG00000025891 | short stature homeobox |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| uncx4.1 | dr10_dc_chr1_+_8605984_8606049 | -0.89 | 4.4e-06 | Click! |
| shox2 | dr10_dc_chr15_-_2224784_2224832 | -0.66 | 5.4e-03 | Click! |
| shox | dr10_dc_chr9_+_34832049_34832055 | -0.60 | 1.4e-02 | Click! |
| vsx1 | dr10_dc_chr17_-_21046246_21046260 | -0.17 | 5.3e-01 | Click! |
Activity profile of shox2_uncx4.1_lhx2a_vsx1_shox motif
Sorted Z-values of shox2_uncx4.1_lhx2a_vsx1_shox motif
Network of associatons between targets according to the STRING database.
First level regulatory network of shox2_uncx4.1_lhx2a_vsx1_shox
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr18_-_40718244 | 23.50 |
ENSDART00000077577
|
si:ch211-132b12.8
|
si:ch211-132b12.8 |
| chr21_+_25740782 | 21.21 |
ENSDART00000021620
|
cldnd
|
claudin d |
| chr24_-_14446593 | 19.71 |
|
|
|
| chr5_+_37303599 | 18.86 |
ENSDART00000097754
ENSDART00000162470 |
tmprss4b
|
transmembrane protease, serine 4b |
| chr14_+_34150130 | 17.67 |
ENSDART00000132193
ENSDART00000141058 |
wnt8a
BX927327.1
|
wingless-type MMTV integration site family, member 8a ENSDARG00000105311 |
| chr11_-_44539778 | 17.60 |
ENSDART00000161846
|
map1lc3c
|
microtubule-associated protein 1 light chain 3 gamma |
| chr8_+_45326435 | 16.82 |
ENSDART00000134161
|
pabpc1l
|
poly(A) binding protein, cytoplasmic 1-like |
| chr16_+_39209567 | 16.05 |
ENSDART00000121756
|
sybu
|
syntabulin (syntaxin-interacting) |
| chr10_-_21404605 | 15.92 |
ENSDART00000125167
|
avd
|
avidin |
| chr10_-_34971985 | 15.80 |
ENSDART00000141201
|
ccna1
|
cyclin A1 |
| chr11_-_6442588 | 15.24 |
ENSDART00000137879
|
zgc:162969
|
zgc:162969 |
| chr18_-_43890836 | 15.06 |
ENSDART00000087382
|
ddx6
|
DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| chr13_-_6875290 | 13.70 |
|
|
|
| chr8_-_23759076 | 13.29 |
ENSDART00000145894
|
zgc:195245
|
zgc:195245 |
| chr10_-_25246786 | 12.73 |
ENSDART00000036906
|
kpna7
|
karyopherin alpha 7 (importin alpha 8) |
| KN149710v1_+_38638 | 12.37 |
|
|
|
| chr24_+_19270877 | 12.19 |
|
|
|
| chr17_+_16038358 | 11.47 |
ENSDART00000155336
|
si:ch73-204p21.2
|
si:ch73-204p21.2 |
| chr10_-_34058331 | 11.06 |
ENSDART00000046599
|
zar1l
|
zygote arrest 1-like |
| KN150456v1_-_19515 | 10.94 |
ENSDART00000168786
|
h1m
|
linker histone H1M |
| chr19_-_20819101 | 10.77 |
ENSDART00000137590
|
dazl
|
deleted in azoospermia-like |
| chr2_-_26941084 | 10.73 |
ENSDART00000134685
ENSDART00000056787 |
zgc:113691
|
zgc:113691 |
| chr24_+_12689711 | 10.71 |
ENSDART00000114762
|
nanog
|
nanog homeobox |
| chr11_-_1524107 | 10.69 |
ENSDART00000110097
|
si:ch73-303b9.1
|
si:ch73-303b9.1 |
| chr19_-_20819477 | 10.36 |
ENSDART00000151356
|
dazl
|
deleted in azoospermia-like |
| chr7_-_47990610 | 9.97 |
ENSDART00000147968
|
rbpms2b
|
RNA binding protein with multiple splicing 2b |
| chr3_+_42383724 | 9.18 |
|
|
|
| chr20_-_23527234 | 9.07 |
ENSDART00000004625
|
zar1
|
zygote arrest 1 |
| chr2_-_26941232 | 8.91 |
ENSDART00000134685
ENSDART00000056787 |
zgc:113691
|
zgc:113691 |
| chr20_-_6542402 | 8.77 |
ENSDART00000054653
|
mcm3l
|
MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), like |
| chr1_-_18118467 | 8.37 |
ENSDART00000142026
|
si:dkey-167i21.2
|
si:dkey-167i21.2 |
| chr24_+_8702288 | 8.30 |
ENSDART00000114810
|
sycp2l
|
synaptonemal complex protein 2-like |
| chr17_+_16038103 | 8.20 |
ENSDART00000155005
|
si:ch73-204p21.2
|
si:ch73-204p21.2 |
| chr19_+_15536640 | 8.05 |
ENSDART00000098970
|
lin28a
|
lin-28 homolog A (C. elegans) |
| chr20_-_29961498 | 7.92 |
ENSDART00000132278
|
rnf144ab
|
ring finger protein 144ab |
| chr13_-_25590425 | 7.78 |
ENSDART00000142404
|
si:dkey-192p21.6
|
si:dkey-192p21.6 |
| chr20_-_29961589 | 7.57 |
ENSDART00000132278
|
rnf144ab
|
ring finger protein 144ab |
| chr2_+_6341404 | 7.36 |
ENSDART00000076700
|
zp3b
|
zona pellucida glycoprotein 3b |
| chr10_-_32550351 | 7.10 |
ENSDART00000129395
|
uvrag
|
UV radiation resistance associated gene |
| chr23_-_33783345 | 7.00 |
ENSDART00000143333
|
pou6f1
|
POU class 6 homeobox 1 |
| chr24_-_23793117 | 6.91 |
|
|
|
| chr1_+_35253862 | 6.90 |
ENSDART00000139636
|
zgc:152968
|
zgc:152968 |
| chr5_+_6391432 | 6.82 |
ENSDART00000170564
ENSDART00000086666 |
stpg2
|
sperm-tail PG-rich repeat containing 2 |
| chr10_-_34971926 | 6.79 |
ENSDART00000141201
|
ccna1
|
cyclin A1 |
| chr23_+_28464194 | 6.76 |
ENSDART00000133736
|
CT025585.1
|
ENSDARG00000093306 |
| chr15_-_16241412 | 6.54 |
ENSDART00000156352
|
si:ch211-259g3.4
|
si:ch211-259g3.4 |
| chr11_-_2437396 | 6.53 |
|
|
|
| chr19_-_18664720 | 6.40 |
ENSDART00000108627
|
snx10a
|
sorting nexin 10a |
| chr14_+_23420053 | 6.21 |
ENSDART00000006373
|
ndfip1
|
Nedd4 family interacting protein 1 |
| chr24_+_12689887 | 6.10 |
ENSDART00000114762
|
nanog
|
nanog homeobox |
| chr10_-_21587697 | 6.04 |
ENSDART00000029122
|
zgc:165539
|
zgc:165539 |
| chr8_-_20198473 | 6.04 |
ENSDART00000063400
|
mllt1a
|
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1a |
| chr3_+_28729443 | 5.89 |
ENSDART00000077235
|
alg1
|
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase |
| chr10_+_19625897 | 5.88 |
|
|
|
| chr21_-_32027717 | 5.72 |
ENSDART00000131651
|
ENSDARG00000073961
|
ENSDARG00000073961 |
| chr2_-_26940965 | 5.71 |
ENSDART00000134685
ENSDART00000056787 |
zgc:113691
|
zgc:113691 |
| chr10_-_25448712 | 5.61 |
ENSDART00000140023
|
grik1a
|
glutamate receptor, ionotropic, kainate 1a |
| chr23_-_35691369 | 5.58 |
ENSDART00000142369
|
mfsd5
|
major facilitator superfamily domain containing 5 |
| chr1_-_54570813 | 5.56 |
ENSDART00000098615
|
nanos3
|
nanos homolog 3 |
| chr23_+_2786407 | 5.51 |
ENSDART00000066086
|
zgc:114123
|
zgc:114123 |
| chr8_-_44247277 | 5.31 |
|
|
|
| chr22_+_17235696 | 5.30 |
ENSDART00000134798
|
tdrd5
|
tudor domain containing 5 |
| chr16_+_25202230 | 5.29 |
ENSDART00000163244
|
si:ch211-261d7.6
|
si:ch211-261d7.6 |
| chr15_-_25164321 | 5.29 |
ENSDART00000154628
|
fam101b
|
family with sequence similarity 101, member B |
| chr24_-_24999240 | 5.24 |
ENSDART00000152104
|
phldb2b
|
pleckstrin homology-like domain, family B, member 2b |
| chr20_+_19304349 | 5.14 |
|
|
|
| chr8_+_11387135 | 5.10 |
|
|
|
| chr11_+_23799984 | 5.04 |
|
|
|
| chr2_-_27892824 | 5.00 |
|
|
|
| chr5_+_57254393 | 4.98 |
ENSDART00000050949
|
btg4
|
B-cell translocation gene 4 |
| chr11_+_24583090 | 4.97 |
ENSDART00000135443
|
kdm5ba
|
lysine (K)-specific demethylase 5Ba |
| chr4_+_9466175 | 4.95 |
ENSDART00000012659
|
zgc:55888
|
zgc:55888 |
| chr6_+_40925259 | 4.87 |
ENSDART00000002728
ENSDART00000145153 |
eif4enif1
|
eukaryotic translation initiation factor 4E nuclear import factor 1 |
| chr16_+_42567707 | 4.70 |
ENSDART00000166640
|
si:ch211-215k15.5
|
si:ch211-215k15.5 |
| chr5_+_37303707 | 4.64 |
ENSDART00000097754
ENSDART00000162470 |
tmprss4b
|
transmembrane protease, serine 4b |
| chr11_-_6442490 | 4.60 |
ENSDART00000137879
|
zgc:162969
|
zgc:162969 |
| chr9_-_35824470 | 4.57 |
ENSDART00000140356
|
zp2l1
|
zona pellucida glycoprotein 2, like 1 |
| chr1_+_18118735 | 4.56 |
ENSDART00000078610
|
slc25a51a
|
solute carrier family 25, member 51a |
| chr23_+_28464143 | 4.53 |
ENSDART00000133736
|
CT025585.1
|
ENSDARG00000093306 |
| chr10_+_6925373 | 4.44 |
ENSDART00000128866
|
ddx4
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 |
| chr8_-_22720007 | 4.35 |
|
|
|
| chr16_-_29452509 | 4.29 |
ENSDART00000148787
|
s100a1
|
S100 calcium binding protein A1 |
| chr8_+_44619220 | 4.15 |
ENSDART00000063392
|
lsm1
|
LSM1, U6 small nuclear RNA associated |
| chr16_-_24727689 | 4.05 |
ENSDART00000167121
|
fxyd6l
|
FXYD domain containing ion transport regulator 6 like |
| chr15_-_43402935 | 4.01 |
ENSDART00000041677
|
serpine2
|
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| chr11_-_44539726 | 3.99 |
ENSDART00000173360
|
map1lc3c
|
microtubule-associated protein 1 light chain 3 gamma |
| chr23_+_28396415 | 3.95 |
ENSDART00000142179
|
birc5b
|
baculoviral IAP repeat containing 5b |
| chr13_+_38688704 | 3.95 |
ENSDART00000110976
|
col19a1
|
collagen, type XIX, alpha 1 |
| chr5_-_61134500 | 3.87 |
ENSDART00000079855
|
im:7138535
|
im:7138535 |
| chr8_+_11287550 | 3.83 |
ENSDART00000115057
|
tjp2b
|
tight junction protein 2b (zona occludens 2) |
| chr23_+_43868027 | 3.79 |
ENSDART00000112598
ENSDART00000169576 |
otud4
|
OTU deubiquitinase 4 |
| chr2_-_15656155 | 3.77 |
ENSDART00000015655
|
tecrl2b
|
trans-2,3-enoyl-CoA reductase-like 2b |
| chr8_+_45326523 | 3.74 |
ENSDART00000145011
|
pabpc1l
|
poly(A) binding protein, cytoplasmic 1-like |
| chr11_-_6442547 | 3.69 |
ENSDART00000137879
|
zgc:162969
|
zgc:162969 |
| chr11_-_34909095 | 3.64 |
ENSDART00000017393
|
traip
|
TRAF-interacting protein |
| chr24_-_14446522 | 3.62 |
|
|
|
| chr24_+_1110206 | 3.58 |
ENSDART00000152063
|
BX005461.1
|
ENSDARG00000096447 |
| chr14_+_23419864 | 3.55 |
ENSDART00000006373
|
ndfip1
|
Nedd4 family interacting protein 1 |
| chr3_-_26052785 | 3.51 |
ENSDART00000147517
|
si:ch211-11k18.4
|
si:ch211-11k18.4 |
| chr20_-_28898117 | 3.49 |
ENSDART00000049462
|
rab15
|
RAB15, member RAS oncogene family |
| chr19_-_20819057 | 3.47 |
ENSDART00000136826
|
dazl
|
deleted in azoospermia-like |
| chr15_-_16241500 | 3.45 |
ENSDART00000156352
|
si:ch211-259g3.4
|
si:ch211-259g3.4 |
| chr2_+_38305689 | 3.45 |
ENSDART00000170672
|
nedd8l
|
neural precursor cell expressed, developmentally down-regulated 8, like |
| chr10_+_17277353 | 3.34 |
ENSDART00000038780
|
sppl3
|
signal peptide peptidase 3 |
| chr2_+_6341345 | 3.33 |
ENSDART00000058256
|
zp3b
|
zona pellucida glycoprotein 3b |
| chr23_+_28464298 | 3.27 |
ENSDART00000133736
|
CT025585.1
|
ENSDARG00000093306 |
| chr23_+_28464642 | 3.22 |
ENSDART00000133736
|
CT025585.1
|
ENSDARG00000093306 |
| chr19_-_18664670 | 3.21 |
ENSDART00000108627
|
snx10a
|
sorting nexin 10a |
| chr24_-_14447519 | 3.18 |
|
|
|
| chr15_-_23484927 | 3.18 |
ENSDART00000148840
|
kmt2a
|
lysine (K)-specific methyltransferase 2A |
| KN150040v1_-_6426 | 3.15 |
|
|
|
| chr2_+_38305772 | 3.14 |
ENSDART00000170672
|
nedd8l
|
neural precursor cell expressed, developmentally down-regulated 8, like |
| chr19_+_39689450 | 3.12 |
|
|
|
| chr14_-_21816253 | 3.09 |
ENSDART00000113752
|
si:dkey-6i22.5
|
si:dkey-6i22.5 |
| chr20_+_29306677 | 3.09 |
ENSDART00000141252
|
katnbl1
|
katanin p80 subunit B-like 1 |
| chr20_-_23355244 | 3.09 |
|
|
|
| chr7_-_54170414 | 3.08 |
|
|
|
| chr24_-_14447825 | 3.08 |
|
|
|
| chr14_+_34150232 | 3.07 |
ENSDART00000148044
|
wnt8a
|
wingless-type MMTV integration site family, member 8a |
| chr7_+_28341426 | 3.05 |
ENSDART00000019991
|
slc7a6os
|
solute carrier family 7, member 6 opposite strand |
| chr8_+_50964745 | 3.03 |
ENSDART00000013870
|
ENSDARG00000007359
|
ENSDARG00000007359 |
| chr8_-_21039978 | 3.02 |
ENSDART00000137606
ENSDART00000146532 |
zgc:112962
|
zgc:112962 |
| chr20_+_29306863 | 3.02 |
ENSDART00000141252
|
katnbl1
|
katanin p80 subunit B-like 1 |
| chr14_+_25950244 | 3.01 |
ENSDART00000113804
ENSDART00000159054 |
CCDC69
|
coiled-coil domain containing 69 |
| chr24_-_14447655 | 2.97 |
|
|
|
| chr6_+_18941135 | 2.94 |
ENSDART00000044519
|
cx44.2
|
connexin 44.2 |
| chr24_+_16402587 | 2.91 |
ENSDART00000164319
|
sema5a
|
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| chr8_-_23591293 | 2.89 |
ENSDART00000025024
|
slc38a5b
|
solute carrier family 38, member 5b |
| chr17_-_45021393 | 2.88 |
|
|
|
| chr14_-_8634381 | 2.87 |
ENSDART00000129030
|
zgc:153681
|
zgc:153681 |
| chr23_-_33692244 | 2.81 |
|
|
|
| chr4_+_9466147 | 2.80 |
ENSDART00000012659
|
zgc:55888
|
zgc:55888 |
| chr20_-_37910887 | 2.77 |
ENSDART00000147529
|
batf3
|
basic leucine zipper transcription factor, ATF-like 3 |
| chr8_-_25015215 | 2.76 |
ENSDART00000170511
|
nfyal
|
nuclear transcription factor Y, alpha, like |
| chr11_+_34909167 | 2.76 |
ENSDART00000110839
|
mon1a
|
MON1 secretory trafficking family member A |
| chr20_+_6542597 | 2.76 |
|
|
|
| chr11_+_34909244 | 2.75 |
ENSDART00000110839
|
mon1a
|
MON1 secretory trafficking family member A |
| chr3_-_20944579 | 2.72 |
ENSDART00000153739
|
nlk1
|
nemo-like kinase, type 1 |
| chr17_+_20231630 | 2.72 |
ENSDART00000155584
|
BX005375.1
|
ENSDARG00000097982 |
| chr15_+_21327206 | 2.70 |
ENSDART00000101000
|
gkup
|
glucuronokinase with putative uridyl pyrophosphorylase |
| chr8_+_41003546 | 2.70 |
ENSDART00000129344
|
gpat2
|
glycerol-3-phosphate acyltransferase 2, mitochondrial |
| chr16_+_25202272 | 2.69 |
ENSDART00000163244
|
si:ch211-261d7.6
|
si:ch211-261d7.6 |
| chr14_-_33605295 | 2.64 |
ENSDART00000168546
|
zdhhc24
|
zinc finger, DHHC-type containing 24 |
| chr3_-_26052601 | 2.64 |
ENSDART00000147517
|
si:ch211-11k18.4
|
si:ch211-11k18.4 |
| chr12_+_22459177 | 2.63 |
ENSDART00000171725
|
capgb
|
capping protein (actin filament), gelsolin-like b |
| chr10_+_6925975 | 2.59 |
|
|
|
| chr25_-_28630138 | 2.58 |
|
|
|
| KN150699v1_-_15078 | 2.58 |
ENSDART00000159861
|
ENSDARG00000098739
|
ENSDARG00000098739 |
| chr19_-_5186692 | 2.58 |
ENSDART00000037007
|
tpi1a
|
triosephosphate isomerase 1a |
| chr8_-_7188791 | 2.56 |
ENSDART00000092426
|
grip2a
|
glutamate receptor interacting protein 2a |
| chr12_+_22459218 | 2.56 |
ENSDART00000171725
|
capgb
|
capping protein (actin filament), gelsolin-like b |
| chr18_+_19467527 | 2.55 |
ENSDART00000079695
|
zwilch
|
zwilch kinetochore protein |
| chr16_+_35448634 | 2.50 |
ENSDART00000171608
|
rab42b
|
RAB42, member RAS oncogene family |
| chr2_-_38380883 | 2.49 |
ENSDART00000088026
|
prmt5
|
protein arginine methyltransferase 5 |
| chr21_+_34053739 | 2.47 |
ENSDART00000147519
|
mtmr1b
|
myotubularin related protein 1b |
| chr10_+_35209240 | 2.46 |
ENSDART00000126105
|
nsun5
|
NOP2/Sun domain family, member 5 |
| chr19_-_19806070 | 2.44 |
ENSDART00000165206
|
smarcc1b
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1b |
| chr7_+_23752492 | 2.38 |
ENSDART00000141165
|
tinf2
|
TERF1 (TRF1)-interacting nuclear factor 2 |
| chr16_+_33209956 | 2.36 |
ENSDART00000101943
|
rragca
|
Ras-related GTP binding Ca |
| chr15_+_35089305 | 2.36 |
ENSDART00000156515
|
zgc:55621
|
zgc:55621 |
| chr3_-_32741894 | 2.30 |
ENSDART00000075277
|
zgc:113090
|
zgc:113090 |
| chr7_-_54170186 | 2.27 |
|
|
|
| chr17_+_10582214 | 2.27 |
ENSDART00000051527
|
tbpl2
|
TATA box binding protein like 2 |
| chr8_-_5834829 | 2.26 |
ENSDART00000179217
|
ENSDARG00000106522
|
ENSDARG00000106522 |
| chr19_+_42657913 | 2.26 |
ENSDART00000131574
ENSDART00000135436 |
jtb
|
jumping translocation breakpoint |
| chr7_+_24374240 | 2.26 |
ENSDART00000087691
|
gba2
|
glucosidase, beta (bile acid) 2 |
| chr7_-_50974318 | 2.23 |
ENSDART00000174297
|
CR354588.1
|
ENSDARG00000105693 |
| chr23_-_31986679 | 2.20 |
ENSDART00000085054
|
mtfr2
|
mitochondrial fission regulator 2 |
| chr24_+_39630741 | 2.18 |
ENSDART00000132939
|
dcun1d3
|
defective in cullin neddylation 1 domain containing 3 |
| chr25_-_3742327 | 2.17 |
ENSDART00000075663
|
cracr2b
|
calcium release activated channel regulator 2B |
| KN150040v1_+_6648 | 2.16 |
|
|
|
| chr7_+_36628318 | 2.15 |
|
|
|
| chr18_+_20571460 | 2.14 |
ENSDART00000151990
|
wee2
|
WEE1 homolog 2 (S. pombe) |
| chr20_+_27813565 | 2.13 |
ENSDART00000008306
|
zbtb1
|
zinc finger and BTB domain containing 1 |
| chr24_-_14447136 | 2.12 |
|
|
|
| chr2_+_50873843 | 2.11 |
|
|
|
| chr20_-_19611724 | 2.10 |
ENSDART00000168521
|
snx17
|
sorting nexin 17 |
| chr21_+_34053590 | 2.08 |
ENSDART00000147519
ENSDART00000158115 ENSDART00000029599 ENSDART00000145123 |
mtmr1b
|
myotubularin related protein 1b |
| chr17_+_10582044 | 2.07 |
ENSDART00000051527
|
tbpl2
|
TATA box binding protein like 2 |
| chr16_+_25201900 | 2.07 |
ENSDART00000163244
|
si:ch211-261d7.6
|
si:ch211-261d7.6 |
| chr25_-_13394261 | 2.07 |
ENSDART00000056721
|
ldhd
|
lactate dehydrogenase D |
| chr16_+_42567668 | 2.06 |
ENSDART00000166640
|
si:ch211-215k15.5
|
si:ch211-215k15.5 |
| chr6_-_40715613 | 2.05 |
ENSDART00000153702
|
si:ch211-157b11.12
|
si:ch211-157b11.12 |
| chr8_-_1833095 | 2.04 |
ENSDART00000114476
ENSDART00000091235 ENSDART00000140077 |
pi4kab
|
phosphatidylinositol 4-kinase, catalytic, alpha b |
| chr6_-_19556029 | 2.03 |
ENSDART00000136019
|
ppp1r12c
|
protein phosphatase 1, regulatory subunit 12C |
| chr21_-_25765319 | 1.99 |
ENSDART00000101219
|
mettl27
|
methyltransferase like 27 |
| chr14_-_6901209 | 1.98 |
ENSDART00000167994
ENSDART00000166532 |
stox2b
|
storkhead box 2b |
| chr3_-_32205961 | 1.98 |
ENSDART00000156551
|
si:dkey-16p21.8
|
si:dkey-16p21.8 |
| chr18_-_2580747 | 1.97 |
|
|
|
| chr9_-_50304120 | 1.97 |
ENSDART00000161648
ENSDART00000168514 |
scn1a
|
sodium channel, voltage-gated, type I, alpha |
| chr24_-_24999348 | 1.96 |
ENSDART00000152104
|
phldb2b
|
pleckstrin homology-like domain, family B, member 2b |
| chr22_-_17627900 | 1.90 |
ENSDART00000138483
|
si:ch73-243b8.4
|
si:ch73-243b8.4 |
| chr11_-_40154790 | 1.89 |
ENSDART00000086296
|
trim62
|
tripartite motif containing 62 |
| chr22_-_20899539 | 1.87 |
ENSDART00000100642
|
ell
|
elongation factor RNA polymerase II |
| chr16_-_17289585 | 1.84 |
ENSDART00000135146
|
gapdh
|
glyceraldehyde-3-phosphate dehydrogenase |
| chr8_+_26377369 | 1.83 |
ENSDART00000087151
|
amt
|
aminomethyltransferase |
| chr16_-_42105636 | 1.82 |
ENSDART00000102798
|
zp3d.2
|
zona pellucida glycoprotein 3d tandem duplicate 2 |
| chr20_+_32620786 | 1.81 |
ENSDART00000147319
|
scml4
|
sex comb on midleg-like 4 (Drosophila) |
| chr12_+_26785950 | 1.80 |
ENSDART00000087329
|
znf438
|
zinc finger protein 438 |
| chr18_-_20605032 | 1.79 |
ENSDART00000134722
|
bcl2l13
|
BCL2-like 13 (apoptosis facilitator) |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.2 | 26.1 | GO:0060149 | negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967) |
| 5.1 | 20.4 | GO:0039015 | spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111) |
| 4.8 | 19.0 | GO:0043622 | cortical microtubule organization(GO:0043622) |
| 2.5 | 10.0 | GO:0051151 | regulation of smooth muscle cell differentiation(GO:0051150) negative regulation of smooth muscle cell differentiation(GO:0051151) |
| 2.4 | 9.6 | GO:0070986 | left/right axis specification(GO:0070986) |
| 1.7 | 5.2 | GO:1990511 | piRNA biosynthetic process(GO:1990511) |
| 1.6 | 16.0 | GO:0019896 | axonal transport of mitochondrion(GO:0019896) |
| 1.5 | 11.8 | GO:0034063 | stress granule assembly(GO:0034063) |
| 1.4 | 5.5 | GO:0033206 | meiotic cytokinesis(GO:0033206) polar body extrusion after meiotic divisions(GO:0040038) |
| 1.3 | 4.0 | GO:0051311 | meiotic metaphase plate congression(GO:0051311) |
| 1.3 | 3.9 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
| 1.3 | 8.8 | GO:1902975 | cell cycle DNA replication initiation(GO:1902292) nuclear cell cycle DNA replication initiation(GO:1902315) mitotic DNA replication initiation(GO:1902975) |
| 1.1 | 16.6 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 1.1 | 12.7 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 1.0 | 4.9 | GO:0060631 | regulation of meiosis I(GO:0060631) |
| 0.9 | 3.8 | GO:0070498 | interleukin-1-mediated signaling pathway(GO:0070498) |
| 0.9 | 2.6 | GO:0046166 | methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166) |
| 0.8 | 21.2 | GO:0043297 | apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830) |
| 0.8 | 13.7 | GO:0060046 | binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344) |
| 0.7 | 2.8 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
| 0.7 | 4.9 | GO:0090244 | Wnt signaling pathway involved in somitogenesis(GO:0090244) |
| 0.7 | 6.2 | GO:0043046 | DNA methylation involved in gamete generation(GO:0043046) |
| 0.7 | 2.0 | GO:0031048 | chromatin silencing by small RNA(GO:0031048) |
| 0.6 | 9.5 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.6 | 1.2 | GO:0048210 | Golgi vesicle fusion to target membrane(GO:0048210) |
| 0.6 | 0.6 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.5 | 2.6 | GO:0072395 | signal transduction involved in cell cycle checkpoint(GO:0072395) |
| 0.5 | 4.2 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.5 | 1.8 | GO:0019464 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 0.4 | 18.4 | GO:0032436 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800) |
| 0.4 | 1.6 | GO:0042364 | water-soluble vitamin biosynthetic process(GO:0042364) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823) aldehyde biosynthetic process(GO:0046184) |
| 0.4 | 10.9 | GO:0031398 | positive regulation of protein ubiquitination(GO:0031398) |
| 0.4 | 4.8 | GO:0035493 | SNARE complex assembly(GO:0035493) |
| 0.4 | 23.0 | GO:1904029 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029) |
| 0.4 | 1.9 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.4 | 2.2 | GO:0072584 | caveolin-mediated endocytosis(GO:0072584) negative regulation of clathrin-mediated endocytosis(GO:1900186) regulation of caveolin-mediated endocytosis(GO:2001286) negative regulation of caveolin-mediated endocytosis(GO:2001287) |
| 0.4 | 10.9 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.3 | 3.1 | GO:0048532 | anatomical structure arrangement(GO:0048532) |
| 0.3 | 2.0 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 0.3 | 1.0 | GO:0051645 | Golgi localization(GO:0051645) |
| 0.3 | 4.4 | GO:0051445 | regulation of meiotic cell cycle(GO:0051445) |
| 0.3 | 1.5 | GO:0043268 | positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651) |
| 0.3 | 6.8 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.3 | 3.3 | GO:0006465 | signal peptide processing(GO:0006465) |
| 0.3 | 3.8 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.3 | 4.3 | GO:0016233 | telomere capping(GO:0016233) |
| 0.3 | 3.2 | GO:0048339 | paraxial mesoderm development(GO:0048339) |
| 0.3 | 2.3 | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153) |
| 0.3 | 3.6 | GO:1902305 | regulation of sodium ion transmembrane transport(GO:1902305) regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.3 | 2.3 | GO:0006622 | protein targeting to lysosome(GO:0006622) |
| 0.3 | 1.5 | GO:0099514 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.2 | 1.0 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 0.2 | 1.0 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.2 | 1.2 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.2 | 6.9 | GO:0006623 | protein targeting to vacuole(GO:0006623) |
| 0.2 | 1.1 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.2 | 3.5 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.2 | 2.9 | GO:0050796 | regulation of insulin secretion(GO:0050796) |
| 0.2 | 0.8 | GO:0097577 | intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577) |
| 0.2 | 1.5 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.2 | 5.6 | GO:0048599 | oocyte development(GO:0048599) |
| 0.2 | 0.7 | GO:0046078 | dUMP biosynthetic process(GO:0006226) dUMP metabolic process(GO:0046078) |
| 0.2 | 1.8 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) CDP-diacylglycerol metabolic process(GO:0046341) |
| 0.2 | 0.5 | GO:0051654 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) establishment of mitochondrion localization(GO:0051654) |
| 0.1 | 3.7 | GO:0035249 | synaptic transmission, glutamatergic(GO:0035249) |
| 0.1 | 2.5 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.1 | 3.2 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.1 | 2.1 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.1 | 1.7 | GO:0098734 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
| 0.1 | 1.5 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.1 | 0.9 | GO:0016572 | histone phosphorylation(GO:0016572) |
| 0.1 | 3.9 | GO:0071230 | cellular response to amino acid stimulus(GO:0071230) |
| 0.1 | 0.5 | GO:0043092 | amino acid import(GO:0043090) L-amino acid import(GO:0043092) |
| 0.1 | 0.4 | GO:0030817 | regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761) |
| 0.1 | 0.9 | GO:0070098 | chemokine-mediated signaling pathway(GO:0070098) |
| 0.1 | 0.5 | GO:0010990 | SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.1 | 2.1 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.1 | 0.7 | GO:0035264 | multicellular organism growth(GO:0035264) |
| 0.1 | 4.3 | GO:0018198 | peptidyl-cysteine modification(GO:0018198) |
| 0.1 | 4.5 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.1 | 0.6 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 0.1 | 8.0 | GO:0017148 | negative regulation of translation(GO:0017148) |
| 0.1 | 0.6 | GO:0018342 | protein prenylation(GO:0018342) prenylation(GO:0097354) |
| 0.1 | 1.0 | GO:0042772 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772) |
| 0.1 | 1.2 | GO:0090481 | pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.1 | 0.2 | GO:0051315 | attachment of spindle microtubules to kinetochore(GO:0008608) attachment of mitotic spindle microtubules to kinetochore(GO:0051315) |
| 0.1 | 0.6 | GO:0034122 | negative regulation of toll-like receptor signaling pathway(GO:0034122) |
| 0.1 | 10.1 | GO:0070507 | regulation of microtubule cytoskeleton organization(GO:0070507) |
| 0.1 | 1.8 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.1 | 1.6 | GO:0021952 | central nervous system projection neuron axonogenesis(GO:0021952) |
| 0.1 | 1.0 | GO:0017121 | phospholipid scrambling(GO:0017121) |
| 0.1 | 2.2 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.1 | 6.1 | GO:0015698 | inorganic anion transport(GO:0015698) |
| 0.1 | 5.5 | GO:0045930 | negative regulation of mitotic cell cycle(GO:0045930) |
| 0.1 | 2.4 | GO:0042761 | very long-chain fatty acid biosynthetic process(GO:0042761) |
| 0.1 | 1.6 | GO:0099518 | vesicle cytoskeletal trafficking(GO:0099518) |
| 0.1 | 0.7 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.1 | 0.9 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.1 | 0.2 | GO:1900364 | negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364) |
| 0.1 | 0.3 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 0.1 | 1.2 | GO:0072310 | glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310) |
| 0.1 | 2.5 | GO:0000281 | mitotic cytokinesis(GO:0000281) |
| 0.1 | 1.5 | GO:0008078 | mesodermal cell migration(GO:0008078) |
| 0.1 | 0.2 | GO:0043504 | mitochondrial DNA repair(GO:0043504) |
| 0.1 | 6.6 | GO:0006338 | chromatin remodeling(GO:0006338) |
| 0.1 | 3.4 | GO:0072329 | monocarboxylic acid catabolic process(GO:0072329) |
| 0.1 | 0.5 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
| 0.0 | 0.9 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
| 0.0 | 1.6 | GO:0032543 | mitochondrial translation(GO:0032543) |
| 0.0 | 0.2 | GO:0071922 | regulation of sister chromatid cohesion(GO:0007063) regulation of cohesin loading(GO:0071922) |
| 0.0 | 4.3 | GO:0006352 | DNA-templated transcription, initiation(GO:0006352) |
| 0.0 | 0.4 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.0 | 0.8 | GO:1903321 | negative regulation of protein ubiquitination(GO:0031397) negative regulation of protein modification by small protein conjugation or removal(GO:1903321) |
| 0.0 | 0.4 | GO:0046146 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.0 | 0.6 | GO:0008354 | germ cell migration(GO:0008354) |
| 0.0 | 2.6 | GO:0030177 | positive regulation of Wnt signaling pathway(GO:0030177) |
| 0.0 | 1.0 | GO:0007605 | sensory perception of sound(GO:0007605) |
| 0.0 | 1.9 | GO:0016575 | histone deacetylation(GO:0016575) |
| 0.0 | 1.0 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.4 | GO:0061383 | trabecula morphogenesis(GO:0061383) heart trabecula morphogenesis(GO:0061384) |
| 0.0 | 1.3 | GO:0010951 | negative regulation of endopeptidase activity(GO:0010951) |
| 0.0 | 0.2 | GO:1901907 | purine nucleoside monophosphate catabolic process(GO:0009128) ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
| 0.0 | 0.2 | GO:2001106 | regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.0 | 1.4 | GO:0030166 | proteoglycan biosynthetic process(GO:0030166) |
| 0.0 | 0.6 | GO:0014066 | regulation of phosphatidylinositol 3-kinase signaling(GO:0014066) positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068) |
| 0.0 | 0.7 | GO:0007050 | cell cycle arrest(GO:0007050) |
| 0.0 | 1.5 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.0 | 1.1 | GO:0048278 | vesicle docking(GO:0048278) |
| 0.0 | 0.7 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.0 | 1.1 | GO:0051260 | protein homooligomerization(GO:0051260) |
| 0.0 | 0.5 | GO:0071427 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
| 0.0 | 0.2 | GO:0040001 | establishment of mitotic spindle localization(GO:0040001) |
| 0.0 | 0.5 | GO:0051607 | defense response to virus(GO:0051607) |
| 0.0 | 0.3 | GO:0043967 | histone H4 acetylation(GO:0043967) |
| 0.0 | 0.6 | GO:0003341 | cilium movement(GO:0003341) |
| 0.0 | 0.2 | GO:0006596 | polyamine biosynthetic process(GO:0006596) |
| 0.0 | 1.8 | GO:0016197 | endosomal transport(GO:0016197) |
| 0.0 | 1.1 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 0.3 | GO:0043524 | negative regulation of neuron apoptotic process(GO:0043524) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.5 | 22.6 | GO:0097124 | cyclin A2-CDK2 complex(GO:0097124) |
| 5.1 | 20.4 | GO:0097189 | apoptotic body(GO:0097189) |
| 2.1 | 6.2 | GO:0033391 | chromatoid body(GO:0033391) |
| 1.0 | 3.1 | GO:0000818 | nuclear MIS12/MIND complex(GO:0000818) |
| 1.0 | 32.3 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.8 | 4.2 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 0.7 | 10.3 | GO:0045180 | basal cortex(GO:0045180) |
| 0.7 | 3.3 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
| 0.6 | 3.9 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.6 | 16.0 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.6 | 17.1 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.6 | 4.3 | GO:0070187 | telosome(GO:0070187) |
| 0.6 | 11.7 | GO:0043186 | P granule(GO:0043186) |
| 0.6 | 3.9 | GO:0034448 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.5 | 4.9 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.5 | 8.8 | GO:0042555 | MCM complex(GO:0042555) |
| 0.4 | 3.5 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
| 0.3 | 0.9 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.3 | 22.7 | GO:0005923 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.3 | 2.8 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.3 | 2.9 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.2 | 2.2 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.2 | 0.7 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.2 | 0.5 | GO:0070390 | transcription export complex 2(GO:0070390) |
| 0.2 | 2.4 | GO:0071564 | npBAF complex(GO:0071564) |
| 0.1 | 4.9 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.1 | 6.7 | GO:0001726 | ruffle(GO:0001726) |
| 0.1 | 3.2 | GO:0044665 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.1 | 10.9 | GO:0000786 | nucleosome(GO:0000786) |
| 0.1 | 2.0 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 1.7 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.1 | 0.9 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 1.2 | GO:0032154 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 0.4 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
| 0.1 | 21.5 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.1 | 1.1 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.1 | 0.7 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.1 | 0.7 | GO:0005868 | cytoplasmic dynein complex(GO:0005868) |
| 0.1 | 0.2 | GO:0035101 | FACT complex(GO:0035101) |
| 0.1 | 0.6 | GO:0000974 | Prp19 complex(GO:0000974) |
| 0.1 | 2.5 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 0.7 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.0 | 1.2 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 2.1 | GO:0031970 | mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970) |
| 0.0 | 2.4 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.5 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 0.3 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.0 | 5.6 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
| 0.0 | 2.6 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 0.2 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.0 | 0.4 | GO:0044666 | MLL3/4 complex(GO:0044666) |
| 0.0 | 2.5 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.0 | 5.3 | GO:0005813 | centrosome(GO:0005813) |
| 0.0 | 0.2 | GO:0030915 | Smc5-Smc6 complex(GO:0030915) |
| 0.0 | 16.3 | GO:0005654 | nucleoplasm(GO:0005654) |
| 0.0 | 2.2 | GO:0005769 | early endosome(GO:0005769) |
| 0.0 | 1.2 | GO:0031228 | integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228) |
| 0.0 | 6.2 | GO:0005694 | chromosome(GO:0005694) |
| 0.0 | 1.1 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 1.4 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 2.0 | GO:0005938 | cell cortex(GO:0005938) |
| 0.0 | 1.1 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 0.2 | GO:0035869 | ciliary transition zone(GO:0035869) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 18.1 | GO:1903231 | mRNA binding involved in posttranscriptional gene silencing(GO:1903231) |
| 3.2 | 15.9 | GO:0009374 | biotin binding(GO:0009374) |
| 2.4 | 26.1 | GO:0008494 | translation activator activity(GO:0008494) |
| 1.7 | 19.2 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 1.4 | 10.9 | GO:0050699 | WW domain binding(GO:0050699) |
| 1.3 | 3.9 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 1.2 | 10.7 | GO:0035804 | structural constituent of egg coat(GO:0035804) |
| 1.1 | 16.0 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.9 | 2.6 | GO:0004807 | triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929) |
| 0.8 | 23.5 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.8 | 12.7 | GO:0061608 | nuclear import signal receptor activity(GO:0061608) |
| 0.7 | 2.8 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
| 0.7 | 3.5 | GO:0004128 | cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128) |
| 0.7 | 2.1 | GO:0004457 | lactate dehydrogenase activity(GO:0004457) |
| 0.7 | 4.6 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.6 | 20.3 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.6 | 3.5 | GO:0004366 | glycerol-3-phosphate O-acyltransferase activity(GO:0004366) |
| 0.6 | 3.3 | GO:0042500 | aspartic endopeptidase activity, intramembrane cleaving(GO:0042500) |
| 0.5 | 6.0 | GO:1904315 | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315) |
| 0.5 | 4.5 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.5 | 16.9 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.4 | 1.7 | GO:0034584 | piRNA binding(GO:0034584) |
| 0.4 | 3.0 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.4 | 2.6 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.4 | 8.8 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.4 | 24.2 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.3 | 3.8 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.3 | 2.0 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.3 | 3.6 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.3 | 24.2 | GO:0031625 | ubiquitin protein ligase binding(GO:0031625) |
| 0.3 | 1.8 | GO:0004605 | phosphatidate cytidylyltransferase activity(GO:0004605) |
| 0.3 | 1.5 | GO:0017081 | chloride channel regulator activity(GO:0017081) chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870) |
| 0.3 | 4.0 | GO:0043028 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028) |
| 0.3 | 0.9 | GO:0031730 | CCR1 chemokine receptor binding(GO:0031726) CCR4 chemokine receptor binding(GO:0031729) CCR5 chemokine receptor binding(GO:0031730) |
| 0.3 | 55.0 | GO:0042802 | identical protein binding(GO:0042802) |
| 0.3 | 10.9 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.3 | 1.1 | GO:0046624 | ceramide transporter activity(GO:0035620) sphingolipid transporter activity(GO:0046624) ceramide 1-phosphate binding(GO:1902387) ceramide 1-phosphate transporter activity(GO:1902388) |
| 0.3 | 1.9 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.2 | 2.1 | GO:0016531 | copper chaperone activity(GO:0016531) |
| 0.2 | 16.0 | GO:0003724 | RNA helicase activity(GO:0003724) |
| 0.2 | 4.3 | GO:0016251 | obsolete general RNA polymerase II transcription factor activity(GO:0016251) |
| 0.2 | 3.2 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.2 | 5.9 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.2 | 1.0 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 0.2 | 1.6 | GO:0016641 | oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641) |
| 0.2 | 1.0 | GO:0005163 | nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165) |
| 0.2 | 1.1 | GO:0035197 | siRNA binding(GO:0035197) |
| 0.2 | 4.3 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.2 | 2.7 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.2 | 3.5 | GO:0016769 | transferase activity, transferring nitrogenous groups(GO:0016769) |
| 0.2 | 4.2 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.2 | 1.0 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.2 | 0.5 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.2 | 6.2 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.2 | 0.9 | GO:0005537 | mannose binding(GO:0005537) |
| 0.1 | 1.6 | GO:0031267 | small GTPase binding(GO:0031267) |
| 0.1 | 0.9 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.1 | 0.7 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.1 | 1.5 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.1 | 1.0 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 0.9 | GO:0043295 | glutathione binding(GO:0043295) |
| 0.1 | 1.1 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
| 0.1 | 0.7 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.1 | 0.5 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.1 | 1.2 | GO:0005459 | UDP-galactose transmembrane transporter activity(GO:0005459) |
| 0.1 | 0.7 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.1 | 1.9 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 0.8 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.1 | 4.9 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.1 | 0.8 | GO:0004322 | ferroxidase activity(GO:0004322) ferric iron binding(GO:0008199) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.1 | 0.4 | GO:0101006 | protein histidine phosphatase activity(GO:0101006) |
| 0.1 | 7.4 | GO:0004527 | exonuclease activity(GO:0004527) |
| 0.1 | 0.6 | GO:0008318 | protein prenyltransferase activity(GO:0008318) |
| 0.1 | 0.7 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
| 0.1 | 1.5 | GO:0008474 | palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599) |
| 0.1 | 1.3 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.1 | 1.4 | GO:0035250 | UDP-galactosyltransferase activity(GO:0035250) |
| 0.1 | 4.3 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 2.0 | GO:0001103 | RNA polymerase II repressing transcription factor binding(GO:0001103) |
| 0.1 | 1.0 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.1 | 0.3 | GO:0004415 | hyalurononglucosaminidase activity(GO:0004415) |
| 0.1 | 11.2 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.1 | 3.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.1 | 2.5 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.1 | 0.7 | GO:0045505 | dynein intermediate chain binding(GO:0045505) |
| 0.1 | 0.2 | GO:0003896 | DNA primase activity(GO:0003896) |
| 0.1 | 4.6 | GO:0015103 | inorganic anion transmembrane transporter activity(GO:0015103) |
| 0.1 | 5.9 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.0 | 0.5 | GO:0005283 | sodium:amino acid symporter activity(GO:0005283) |
| 0.0 | 0.4 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.0 | 2.4 | GO:0016627 | oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627) |
| 0.0 | 0.2 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.0 | 0.7 | GO:0019239 | deaminase activity(GO:0019239) |
| 0.0 | 4.7 | GO:0019901 | protein kinase binding(GO:0019901) |
| 0.0 | 0.2 | GO:0070035 | ATP-dependent DNA helicase activity(GO:0004003) ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035) |
| 0.0 | 0.5 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 11.7 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.2 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) |
| 0.0 | 0.6 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 1.9 | GO:0019904 | protein domain specific binding(GO:0019904) |
| 0.0 | 3.8 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.0 | 0.3 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393) |
| 0.0 | 0.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.0 | 0.7 | GO:0009055 | electron carrier activity(GO:0009055) |
| 0.0 | 0.2 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.4 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 2.6 | GO:0008168 | methyltransferase activity(GO:0008168) |
| 0.0 | 2.0 | GO:0008017 | microtubule binding(GO:0008017) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 22.6 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.3 | 22.4 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.3 | 2.8 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 2.0 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 4.4 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.1 | 4.0 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 5.6 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 1.3 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 1.2 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.0 | 2.2 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 1.4 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.1 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
| 0.0 | 0.9 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 0.2 | PID ARF 3PATHWAY | Arf1 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 22.6 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 1.0 | 15.9 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.2 | 4.9 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.2 | 2.3 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.2 | 1.0 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.2 | 1.5 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.2 | 3.5 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.2 | 5.9 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.1 | 1.2 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 1.8 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 3.9 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 4.3 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.1 | 0.5 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.1 | 0.4 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 2.3 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.1 | 0.8 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.1 | 1.4 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.1 | 1.9 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.1 | 2.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 3.0 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.1 | 0.7 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.1 | 1.2 | REACTOME INTERFERON ALPHA BETA SIGNALING | Genes involved in Interferon alpha/beta signaling |
| 0.0 | 0.7 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.0 | 2.7 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 0.7 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 1.0 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.0 | 0.9 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 0.0 | 0.8 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.0 | 0.4 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.0 | 0.6 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.4 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.0 | 0.3 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 0.0 | 0.2 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.0 | 0.1 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |