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Results for si:ch1073-357b18.4

Z-value: 4.36

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Transcription factors associated with si:ch1073-357b18.4

Gene Symbol Gene ID Gene Info
ENSDARG00000096602 si_ch1073-357b18.4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
si:ch1073-357b18.4dr10_dc_chr12_-_280962_2810880.683.8e-03Click!

Activity profile of si:ch1073-357b18.4 motif

Sorted Z-values of si:ch1073-357b18.4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of si:ch1073-357b18.4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_24063849 13.57 ENSDART00000135084
apolipoprotein A-II
chr25_-_32344881 13.07 ENSDART00000012862
ISL LIM homeobox 2a
chr19_-_5441932 12.80 ENSDART00000105034
type I cytokeratin, enveloping layer, like
chr17_+_19479310 11.19 ENSDART00000077804
solute carrier family 22, member 15
chr22_-_37414940 10.87 ENSDART00000104493
SRY (sex determining region Y)-box 2
chr9_-_47041677 9.49 ENSDART00000054137
insulin-like growth factor binding protein 5b
chr6_-_39315024 9.41 ENSDART00000012644
keratin 4
chr2_+_22324846 9.31 ENSDART00000044371
thymocyte selection-associated high mobility group box
chr25_-_30845998 8.82 ENSDART00000027661
myogenic differentiation 1
chr14_-_24463906 8.61 ENSDART00000126199
slit homolog 3 (Drosophila)
chr3_+_23557320 8.39 ENSDART00000046638
homeobox B8a
chr23_+_23559246 8.38 ENSDART00000172214
agrin
chr4_-_12863235 8.20 ENSDART00000080536
high mobility group AT-hook 2
chr19_-_5435448 7.99 ENSDART00000027701
keratin 92
chr9_+_54612545 7.98 ENSDART00000104475
thymosin, beta 4 x
chr13_+_1595986 7.78

chr3_+_23546802 7.77 ENSDART00000023674
homeobox B9a
chr9_-_23081918 7.69 ENSDART00000143888
nebulin
chr25_+_31547276 7.31 ENSDART00000090727
dual oxidase
chr5_+_37053530 7.15 ENSDART00000161051
spectrin, beta, non-erythrocytic 2
chr3_-_6078015 7.12 ENSDART00000165715
ENSDARG00000098850
chr18_+_38768524 7.10 ENSDART00000143735
si:ch211-215d8.2
chr23_-_31446156 7.00 ENSDART00000053367
high mobility group nucleosomal binding domain 3
chr4_-_12862869 6.99 ENSDART00000080536
high mobility group AT-hook 2
chr13_+_28574593 6.99 ENSDART00000126845
LIM domain binding 1a
chr2_+_55859099 6.97 ENSDART00000097753
ENSDART00000141688
nicotinamide riboside kinase 2
chr5_+_12786897 6.91

chr16_-_40891298 6.88

chr6_+_56163589 6.86 ENSDART00000150219
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr13_+_11305781 6.83

chr9_-_23081250 6.82

chr21_-_28883441 6.70 ENSDART00000132884
CXXC finger protein 5a
chr14_+_21531709 6.63 ENSDART00000144367
C-terminal binding protein 1
chr23_-_9924987 6.62 ENSDART00000005015
protein kinase C binding protein 1, like
chr12_+_7421078 6.61 ENSDART00000163114
phytanoyl-CoA 2-hydroxylase interacting protein-like b
chr4_-_8610868 6.61 ENSDART00000067322
F-box and leucine-rich repeat protein 14b
chr4_-_12862708 6.59 ENSDART00000080536
high mobility group AT-hook 2
chr24_-_31772736 6.57

chr6_+_28886741 6.53 ENSDART00000065137
tumor protein p63
chr7_+_15623852 6.45 ENSDART00000161608
paired box 6b
chr19_-_22956977 6.42 ENSDART00000019505
plectin a
chr7_+_20699191 6.38 ENSDART00000062003
ephrin-B3b
chr1_+_35933511 6.37 ENSDART00000010632
endothelin receptor type Aa
chr11_+_5745644 6.33 ENSDART00000179139
AT rich interactive domain 3A (BRIGHT-like)
chr10_+_6316944 6.32 ENSDART00000162428
tropomyosin 2 (beta)
chr3_+_34540552 6.31 ENSDART00000007073
ENSDART00000133457
distal-less homeobox 4a
chr7_-_11812634 6.29 ENSDART00000101537
mex-3 RNA binding family member B
chr15_-_41288480 6.28 ENSDART00000155359
single-pass membrane protein with coiled-coil domains 4
chr21_-_41286846 6.28 ENSDART00000167339
muscle segment homeobox 2b
chr9_-_55204516 6.24

chr24_+_24308055 6.02

chr1_-_16894589 5.99 ENSDART00000039917
acyl-CoA synthetase long-chain family member 1a
chr8_+_28584427 5.96 ENSDART00000097213
transcription factor 15
chr13_+_29640492 5.88 ENSDART00000160944
paired box 2a
chr4_-_20435099 5.87 ENSDART00000055317
leucine rich repeat containing 17
chr7_+_19300351 5.79 ENSDART00000169060
si:ch211-212k18.5
chr9_+_21911860 5.78 ENSDART00000102021
SRY (sex determining region Y)-box 1a
chr14_-_32624823 5.77 ENSDART00000114973
caudal type homeobox 4
chr12_-_36415239 5.68

chr19_-_5464238 5.64 ENSDART00000105806
type I cytokeratin, enveloping layer
chr16_-_29593569 5.63 ENSDART00000150028
one cut domain, family member, like
chr20_-_53560663 5.60 ENSDART00000146001
WAS protein family, member 1
chr17_-_44135924 5.56 ENSDART00000156648
orthodenticle homeobox 2
chr14_-_26406720 5.56 ENSDART00000078563
neurogenin 1
chr10_+_18994733 5.55 ENSDART00000146517
dihydropyrimidinase-like 2b
chr8_+_17148864 5.52 ENSDART00000140531
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr2_-_18275994 5.51 ENSDART00000155124
protein tyrosine phosphatase, receptor type, f, b
chr2_+_47864913 5.50

chr25_+_19636029 5.50 ENSDART00000067354
zgc:101783
chr24_-_26165778 5.48 ENSDART00000080113
apolipoprotein Db
chr6_-_8501230 5.48 ENSDART00000143956
caveolae associated protein 2b
chr10_+_22759607 5.46

chr15_-_18638643 5.41 ENSDART00000142010
neural cell adhesion molecule 1b
chr23_-_29138952 5.36 ENSDART00000002812
castor zinc finger 1
chr17_+_33766838 5.29 ENSDART00000132294
fucosyltransferase 8a (alpha (1,6) fucosyltransferase)
chr19_+_3713027 5.28 ENSDART00000125673
neural precursor cell expressed, developmentally down-regulated 9
chr10_+_10428297 5.25 ENSDART00000179214
sarcosine dehydrogenase
chr15_-_14616083 5.25 ENSDART00000171169
numb homolog (Drosophila)-like
chr25_-_13580057 5.13 ENSDART00000090226
zinc finger protein 319b
chr14_-_40454194 5.08 ENSDART00000166621
E74-like factor 1 (ets domain transcription factor)
chr13_+_19191645 5.08 ENSDART00000058036
empty spiracles homeobox 2
chr1_-_19900799 5.07 ENSDART00000124770
UDP glycosyltransferase 8
chr2_-_30198789 5.03 ENSDART00000019149
ribosomal protein L7
chr1_-_6976446 5.00 ENSDART00000085203
ephrin-B2b
chr24_-_40968409 4.97 ENSDART00000169315
ENSDART00000171543
slow myosin heavy chain 1
chr3_-_44113070 4.96 ENSDART00000160717
zinc finger protein 750
chr7_-_52283383 4.96 ENSDART00000165649
transcription factor 12
chr13_-_1980818 4.94 ENSDART00000110814
family with sequence similarity 83, member B
chr7_-_33558939 4.89 ENSDART00000074729
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr1_+_30992553 4.88 ENSDART00000112333
cyclin and CBS domain divalent metal cation transport mediator 2b
chr24_+_21200975 4.86 ENSDART00000126519
shisa family member 2b
chr3_+_12287067 4.86 ENSDART00000158060
vasorin b
chr23_+_10552781 4.85

chr13_+_11305846 4.84

chr9_-_54126121 4.77 ENSDART00000126314
protocadherin 8
chr19_-_5142310 4.74 ENSDART00000130062
chromodomain helicase DNA binding protein 4a
chr5_-_41672394 4.72 ENSDART00000164363
si:ch211-207c6.2
chr3_+_48362748 4.71 ENSDART00000157199
MKL/myocardin-like 2b
chr1_+_45503061 4.63 ENSDART00000010894
SRY (sex determining region Y)-box 1b
chr21_-_11561855 4.63 ENSDART00000162426
calpastatin
chr19_+_14197118 4.61 ENSDART00000166230
trophoblast glycoprotein a
chr15_-_16076874 4.59 ENSDART00000144138
HNF1 homeobox Ba
chr6_-_32106882 4.55 ENSDART00000144772
ENSDARG00000095311
chr1_+_41523935 4.55 ENSDART00000110860
catenin (cadherin-associated protein), alpha 2
chr25_+_13580892 4.53 ENSDART00000007029
U6 snRNA biogenesis 1
chr6_-_49674729 4.51 ENSDART00000112226
adenomatosis polyposis coli down-regulated 1-like
chr25_+_34135377 4.50 ENSDART00000157519
transient receptor potential cation channel, subfamily M, member 1b
chr20_+_40247918 4.42 ENSDART00000121818
triadin
chr12_-_34621359 4.42

chr5_+_59845054 4.39 ENSDART00000130565
transmembrane protein 132E
chr7_+_56375651 4.36 ENSDART00000112242
zgc:194679
chr5_-_24568752 4.35 ENSDART00000145061
patatin-like phospholipase domain containing 7b
chr1_-_46047321 4.35

chr14_+_7626822 4.29 ENSDART00000109941
CXXC finger protein 5b
chr16_-_10089440 4.29 ENSDART00000066372
inhibitor of DNA binding 4
chr17_+_24668907 4.25 ENSDART00000034263
ENSDART00000135794
selenoprotein N, 1
chr3_-_39287733 4.23

chr25_-_13456748 4.22 ENSDART00000139290
anoctamin 10b
chr12_-_36565562 4.21 ENSDART00000153259
si:ch211-216b21.2
chr2_-_49114158 4.21

chr10_-_27261937 4.18

chr13_+_1741432 4.17 ENSDART00000161162
bone morphogenetic protein 5
chr5_+_59844830 4.16 ENSDART00000130565
transmembrane protein 132E
chr19_+_34582100 4.16 ENSDART00000135592
POC1 centriolar protein homolog B (Chlamydomonas), like
chr19_-_30975279 4.16 ENSDART00000171006
hippocalcin like 4
chr14_+_49921861 4.14 ENSDART00000173240
zgc:154054
chr19_-_22957035 4.08 ENSDART00000019505
plectin a
chr12_+_28252623 4.08 ENSDART00000066294
cyclin-dependent kinase 5, regulatory subunit 1b (p35)
chr19_-_42721857 4.06 ENSDART00000150919
ENSDART00000151034
si:ch211-191i18.2
chr6_-_43806125 4.06

chr10_+_10393377 4.05 ENSDART00000109432
cerebral endothelial cell adhesion molecule
chr5_-_70939686 4.03

chr13_+_17541579 4.03 ENSDART00000137776
catechol-O-methyltransferase domain containing 1
chr8_-_31044627 4.01 ENSDART00000109885
small nuclear ribonucleoprotein 200 (U5)
chr23_-_18203680 3.96 ENSDART00000016976
nuclear casein kinase and cyclin-dependent kinase substrate 1b
chr20_+_27194162 3.96 ENSDART00000024595
ubiquitin protein ligase E3 component n-recognin 7
chr19_+_20202737 3.94 ENSDART00000164677
homeobox A4a
chr13_+_1741474 3.93 ENSDART00000161162
bone morphogenetic protein 5
chr19_-_10635235 3.86 ENSDART00000104539
lens intrinsic membrane protein 2.4
chr17_+_38314814 3.86 ENSDART00000017493
NK2 homeobox 1
chr25_-_13057808 3.84 ENSDART00000172571
sphingomyelin phosphodiesterase 3, neutral
chr12_+_27026112 3.83 ENSDART00000076154
homeobox B8b
chr12_-_7951265 3.82

chr8_+_6989445 3.82 ENSDART00000134440
glycerol-3-phosphate dehydrogenase 1a
chr20_-_8036478 3.81 ENSDART00000083898
phospholipid phosphatase 3
chr10_+_17494274 3.80

chr7_-_33558771 3.78 ENSDART00000074729
uveal autoantigen with coiled-coil domains and ankyrin repeats b
chr9_-_1969197 3.77 ENSDART00000080608
homeobox D10a
chr19_+_23414927 3.73 ENSDART00000151090
growth differentiation factor 6b
chr9_+_8920445 3.69 ENSDART00000147820
carbohydrate kinase domain containing
chr5_-_57016269 3.68 ENSDART00000074264
cytokine receptor family member B12
chr6_-_54103765 3.64 ENSDART00000083880
hyaluronoglucosaminidase 2a
chr2_+_29862841 3.62 ENSDART00000135918
si:ch211-207d6.2
chr3_-_58488929 3.59 ENSDART00000042386
un-named sa1261
chr4_-_16417703 3.58 ENSDART00000013085
decorin
chr10_+_17893555 3.57 ENSDART00000113666
PHD finger protein 24
chr16_-_13733759 3.57 ENSDART00000164344
si:dkeyp-69b9.6
chr6_-_44282665 3.56 ENSDART00000157215
PDZ domain containing RING finger 3b
chr24_+_24924379 3.54 ENSDART00000115165
APC membrane recruitment protein 2
chr1_-_24486146 3.53 ENSDART00000144711
transmembrane protein 154
chr14_-_1081316 3.53

chr9_-_1983772 3.52 ENSDART00000082339
homeobox D12a
chr12_+_2988101 3.52 ENSDART00000044690
ENSDART00000122905
ras-related C3 botulinum toxin substrate 3b (rho family, small GTP binding protein Rac3)
chr19_-_5452918 3.50 ENSDART00000105004
keratin 17
chr16_-_19154920 3.49 ENSDART00000088818
formin homology 2 domain containing 3b
chr13_+_23152038 3.49 ENSDART00000171676
KH domain containing, RNA binding, signal transduction associated 2
chr24_+_19374200 3.48 ENSDART00000056081
ENSDART00000027022
sulfatase 1
chr21_-_24552672 3.44

chr5_+_44722544 3.43 ENSDART00000084411
ADAM metallopeptidase with thrombospondin type 1 motif, 3
chr23_+_11350727 3.41

chr16_+_1073570 3.40

chr8_-_39944817 3.39 ENSDART00000083066
aspartate beta-hydroxylase domain containing 2
chr13_-_49695322 3.37

chr19_-_22182031 3.36 ENSDART00000104279
zinc finger protein 516
chr17_+_38307512 3.35 ENSDART00000005296
NK2 transcription factor related, locus 9 (Drosophila)
chr8_+_39525254 3.33

chr3_-_23513177 3.32 ENSDART00000078425
even-skipped-like1
chr1_-_13547500 3.30 ENSDART00000044896
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr17_-_44133941 3.28 ENSDART00000126097
orthodenticle homeobox 2
chr11_+_19894772 3.27 ENSDART00000103997
FEZ family zinc finger 2
chr3_-_12818954 3.26 ENSDART00000158747
ENSDART00000158815
platelet-derived growth factor alpha polypeptide b
chr11_-_3968366 3.25 ENSDART00000171093
glycosyltransferase 8 domain containing 1
chr11_+_19894390 3.21 ENSDART00000103997
FEZ family zinc finger 2
chr9_-_47042015 3.20 ENSDART00000054137
insulin-like growth factor binding protein 5b
chr23_+_44782492 3.16 ENSDART00000125198
profilin 1
chr14_+_7145893 3.15 ENSDART00000130388
GDNF family receptor alpha 3
chr9_+_32267615 3.15

chr1_+_14451504 3.12 ENSDART00000111475
protocadherin 7a
chr11_-_27253835 3.10 ENSDART00000065889
wingless-type MMTV integration site family, member 7Aa
chr23_-_4175790 3.09 ENSDART00000109807
ENSDARG00000076299
chr14_-_29552242 2.93 ENSDART00000088004
sorbin and SH3 domain containing 2b
chr19_+_38033219 2.93 ENSDART00000158960
thrombospondin, type I, domain containing 7Aa
chr7_-_29300402 2.93 ENSDART00000099477
RAR-related orphan receptor A, paralog b
KN150196v1_+_15525 2.92

chr19_+_42491631 2.91 ENSDART00000150949
nuclear transcription factor Y, gamma
chr3_-_54414513 2.90 ENSDART00000053106
sphingosine-1-phosphate receptor 2
chr19_+_21783429 2.90 ENSDART00000024639
teashirt zinc finger homeobox 1
chr12_-_10384063 2.89 ENSDART00000052004
zgc:153595
chr10_-_7827244 2.87 ENSDART00000111058
myeloid-specific peroxidase
chr17_-_29885237 2.86 ENSDART00000009104
estrogen-related receptor gamma a

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.6 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
2.6 13.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
2.4 7.3 GO:0042554 superoxide anion generation(GO:0042554)
2.4 14.1 GO:0003311 pancreatic D cell differentiation(GO:0003311)
2.2 8.8 GO:0002074 extraocular skeletal muscle development(GO:0002074)
2.2 10.9 GO:0021982 pineal gland development(GO:0021982)
1.9 7.7 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
1.8 5.5 GO:0097374 sensory neuron axon guidance(GO:0097374)
1.4 8.7 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
1.4 5.6 GO:0021516 dorsal spinal cord development(GO:0021516)
1.3 9.3 GO:0050910 detection of mechanical stimulus involved in sensory perception of sound(GO:0050910)
1.3 5.3 GO:1901052 sarcosine metabolic process(GO:1901052)
1.3 12.7 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
1.2 11.0 GO:0060114 vestibular receptor cell differentiation(GO:0060114) vestibular receptor cell development(GO:0060118)
1.2 2.4 GO:1901490 regulation of lymphangiogenesis(GO:1901490) positive regulation of lymphangiogenesis(GO:1901492)
1.2 7.0 GO:0071326 cellular response to carbohydrate stimulus(GO:0071322) cellular response to monosaccharide stimulus(GO:0071326) cellular response to hexose stimulus(GO:0071331) cellular response to glucose stimulus(GO:0071333)
1.1 4.6 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
1.1 6.6 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
1.1 5.3 GO:0090527 actin filament reorganization(GO:0090527)
1.0 9.4 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
1.0 2.9 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.9 4.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.9 5.5 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.9 2.7 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.9 12.3 GO:0036302 atrioventricular canal development(GO:0036302)
0.9 3.5 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.8 4.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.8 4.9 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.8 2.4 GO:0031639 regulation of collagen metabolic process(GO:0010712) regulation of granulocyte differentiation(GO:0030852) plasminogen activation(GO:0031639) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246) regulation of neutrophil differentiation(GO:0045658)
0.8 7.8 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.8 7.7 GO:0048730 epidermis morphogenesis(GO:0048730)
0.8 3.8 GO:0006116 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.8 5.3 GO:0036065 fucosylation(GO:0036065)
0.7 4.5 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.7 1.5 GO:0021703 locus ceruleus development(GO:0021703)
0.7 3.4 GO:0021572 rhombomere 5 development(GO:0021571) rhombomere 6 development(GO:0021572)
0.7 2.0 GO:0061550 cranial ganglion development(GO:0061550)
0.7 10.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.6 9.0 GO:0021654 rhombomere boundary formation(GO:0021654)
0.6 6.4 GO:0042310 vasoconstriction(GO:0042310)
0.6 3.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.6 5.4 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.6 2.3 GO:0045168 cell-cell signaling involved in cell fate commitment(GO:0045168)
0.6 1.7 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.5 1.5 GO:0045905 positive regulation of translational termination(GO:0045905)
0.5 5.5 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.5 2.4 GO:0060579 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) ventral spinal cord interneuron fate commitment(GO:0060579)
0.5 4.7 GO:0051639 actin filament network formation(GO:0051639)
0.5 5.6 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.4 3.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.4 2.0 GO:1902221 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.4 8.6 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.4 6.5 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.4 1.9 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.4 11.8 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.4 1.1 GO:0000388 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)(GO:0000388)
0.4 4.0 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.4 8.6 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.3 1.4 GO:0035776 pronephric proximal tubule development(GO:0035776)
0.3 1.7 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.3 1.9 GO:0046822 regulation of nucleocytoplasmic transport(GO:0046822)
0.3 4.4 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.3 6.8 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.3 2.2 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.3 5.0 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.3 2.7 GO:0031641 regulation of myelination(GO:0031641)
0.3 4.5 GO:0030223 neutrophil differentiation(GO:0030223)
0.3 5.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.3 0.8 GO:0021564 vagus nerve development(GO:0021564)
0.3 6.9 GO:0031167 rRNA methylation(GO:0031167)
0.2 3.8 GO:0061300 cerebellum vasculature development(GO:0061300)
0.2 3.6 GO:0010508 positive regulation of autophagy(GO:0010508)
0.2 0.7 GO:0006481 C-terminal protein methylation(GO:0006481)
0.2 1.8 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.2 0.9 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.2 1.5 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.2 2.9 GO:2000377 regulation of reactive oxygen species metabolic process(GO:2000377)
0.2 6.6 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.2 0.8 GO:0051660 establishment of centrosome localization(GO:0051660)
0.2 2.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2 5.4 GO:0000302 response to reactive oxygen species(GO:0000302)
0.2 1.8 GO:0045471 response to ethanol(GO:0045471)
0.2 4.5 GO:0051262 protein tetramerization(GO:0051262)
0.2 2.5 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.2 1.8 GO:0015693 magnesium ion transport(GO:0015693)
0.2 2.6 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.2 1.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 1.3 GO:0060325 face morphogenesis(GO:0060325)
0.2 2.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 4.1 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.1 5.5 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 3.1 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.1 4.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 6.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 1.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 4.9 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.1 4.8 GO:0030834 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) actin filament capping(GO:0051693)
0.1 9.3 GO:0002521 leukocyte differentiation(GO:0002521)
0.1 2.7 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.1 1.3 GO:0016486 peptide hormone processing(GO:0016486)
0.1 1.7 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.1 4.1 GO:0043406 positive regulation of MAP kinase activity(GO:0043406)
0.1 5.9 GO:0050919 negative chemotaxis(GO:0050919)
0.1 10.1 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.1 6.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.7 GO:0080009 mRNA methylation(GO:0080009)
0.1 3.7 GO:0007599 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.1 0.6 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 2.8 GO:0007601 visual perception(GO:0007601)
0.1 7.6 GO:0006936 muscle contraction(GO:0006936)
0.1 2.9 GO:0071599 otic vesicle development(GO:0071599)
0.1 2.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 8.4 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.1 9.0 GO:0001947 heart looping(GO:0001947)
0.1 2.8 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.1 5.0 GO:0008544 epidermis development(GO:0008544)
0.1 2.1 GO:0006270 DNA replication initiation(GO:0006270)
0.1 6.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.9 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.1 13.6 GO:0000280 nuclear division(GO:0000280)
0.1 0.6 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.1 17.2 GO:0045944 positive regulation of transcription from RNA polymerase II promoter(GO:0045944)
0.0 4.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 5.7 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 2.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 3.9 GO:0030111 regulation of Wnt signaling pathway(GO:0030111)
0.0 0.9 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 2.6 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 4.6 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 1.1 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 1.5 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 1.4 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107) peptidyl-threonine modification(GO:0018210)
0.0 0.4 GO:0048920 posterior lateral line neuromast primordium migration(GO:0048920)
0.0 3.4 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 3.8 GO:0045664 regulation of neuron differentiation(GO:0045664)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.6 GO:0048840 otolith development(GO:0048840)
0.0 3.1 GO:0006364 rRNA processing(GO:0006364)
0.0 1.4 GO:0006334 nucleosome assembly(GO:0006334)
0.0 1.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.1 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 26.0 GO:0006357 regulation of transcription from RNA polymerase II promoter(GO:0006357)
0.0 1.4 GO:0033674 positive regulation of kinase activity(GO:0033674)
0.0 1.2 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.0 1.0 GO:0051169 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0043020 NADPH oxidase complex(GO:0043020)
1.4 7.2 GO:0008091 spectrin(GO:0008091)
1.0 10.5 GO:0030056 hemidesmosome(GO:0030056)
0.6 3.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.6 42.1 GO:0005882 intermediate filament(GO:0005882)
0.5 1.6 GO:0033270 paranode region of axon(GO:0033270)
0.5 5.6 GO:0031209 SCAR complex(GO:0031209)
0.4 2.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 11.0 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.3 2.9 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.3 2.8 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 2.9 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 4.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 14.3 GO:0005795 Golgi stack(GO:0005795)
0.2 1.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 5.5 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.2 2.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.7 GO:0046695 SLIK (SAGA-like) complex(GO:0046695)
0.1 0.6 GO:0043034 costamere(GO:0043034)
0.1 7.7 GO:0030018 Z disc(GO:0030018)
0.1 1.4 GO:0000813 ESCRT I complex(GO:0000813)
0.1 5.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.7 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.1 2.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 4.5 GO:0016459 myosin complex(GO:0016459)
0.1 27.2 GO:0000785 chromatin(GO:0000785)
0.1 13.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 46.6 GO:0005615 extracellular space(GO:0005615)
0.1 20.2 GO:0005576 extracellular region(GO:0005576)
0.1 3.6 GO:0045202 synapse(GO:0045202)
0.1 3.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 1.6 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 17.9 GO:0043005 neuron projection(GO:0043005)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.7 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 18.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.4 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.1 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 8.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.5 GO:0005643 nuclear pore(GO:0005643)
0.0 0.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.7 GO:0005770 late endosome(GO:0005770)
0.0 1.2 GO:0030141 secretory granule(GO:0030141)
0.0 7.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 6.2 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.0 0.8 GO:0016324 apical plasma membrane(GO:0016324) apical part of cell(GO:0045177)
0.0 125.4 GO:0005634 nucleus(GO:0005634)
0.0 1.4 GO:0005764 lysosome(GO:0005764)
0.0 67.5 GO:0016021 integral component of membrane(GO:0016021)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.8 GO:0005694 chromosome(GO:0005694)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 7.3 GO:0016175 NAD(P)H oxidase activity(GO:0016174) superoxide-generating NADPH oxidase activity(GO:0016175)
2.1 14.4 GO:0070888 E-box binding(GO:0070888)
1.8 5.3 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
1.7 7.0 GO:0030274 LIM domain binding(GO:0030274)
1.6 14.5 GO:0048495 Roundabout binding(GO:0048495)
1.6 4.7 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
1.4 7.0 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262)
1.4 6.9 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.3 13.4 GO:0008327 methyl-CpG binding(GO:0008327)
1.3 12.7 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
1.0 4.0 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
1.0 4.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
1.0 10.5 GO:0030506 ankyrin binding(GO:0030506)
0.9 8.1 GO:0070700 BMP receptor binding(GO:0070700)
0.8 4.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.8 5.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.8 3.8 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.7 2.9 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.7 2.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.6 5.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.6 6.1 GO:0008417 fucosyltransferase activity(GO:0008417)
0.6 6.0 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.6 2.4 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.6 5.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.6 10.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.5 4.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.5 4.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.4 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 3.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.4 5.5 GO:0005080 protein kinase C binding(GO:0005080)
0.4 2.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.4 6.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 1.7 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.3 4.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.3 2.2 GO:0015145 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.3 3.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 4.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.3 3.3 GO:0003785 actin monomer binding(GO:0003785)
0.3 2.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 3.1 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 1.8 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.3 4.5 GO:0008143 poly(A) binding(GO:0008143)
0.2 4.9 GO:0005518 collagen binding(GO:0005518)
0.2 4.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.2 3.9 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 0.7 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.2 9.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 2.4 GO:0048018 receptor activator activity(GO:0030546) receptor agonist activity(GO:0048018)
0.2 10.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 5.9 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 7.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 8.0 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.2 1.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 9.3 GO:0031490 chromatin DNA binding(GO:0031490)
0.2 4.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 3.3 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 6.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 2.6 GO:0035497 cAMP response element binding(GO:0035497)
0.1 2.9 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.1 1.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 3.9 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.3 GO:0030165 PDZ domain binding(GO:0030165)
0.1 4.6 GO:0005109 frizzled binding(GO:0005109)
0.1 5.5 GO:0008201 heparin binding(GO:0008201)
0.1 4.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 29.5 GO:0051015 actin filament binding(GO:0051015)
0.1 6.6 GO:0051287 NAD binding(GO:0051287)
0.1 1.8 GO:0035591 signaling adaptor activity(GO:0035591)
0.1 2.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 3.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 1.6 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.1 5.1 GO:0016859 cis-trans isomerase activity(GO:0016859)
0.1 39.4 GO:0005198 structural molecule activity(GO:0005198)
0.1 0.9 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 5.5 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 4.1 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.1 4.5 GO:0005262 calcium channel activity(GO:0005262)
0.1 118.0 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1 3.7 GO:0005125 cytokine activity(GO:0005125)
0.1 3.5 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 2.5 GO:0008194 UDP-glycosyltransferase activity(GO:0008194)
0.0 1.5 GO:0004601 peroxidase activity(GO:0004601)
0.0 14.0 GO:0003712 transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712)
0.0 3.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 3.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 6.7 GO:0016757 transferase activity, transferring glycosyl groups(GO:0016757)
0.0 4.6 GO:0019901 protein kinase binding(GO:0019901)
0.0 12.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.9 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 2.9 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 4.0 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0 2.2 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 5.7 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 1.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.1 GO:0003724 RNA helicase activity(GO:0003724)
0.0 1.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.9 GO:0003779 actin binding(GO:0003779)
0.0 0.5 GO:0008083 growth factor activity(GO:0008083)
0.0 0.3 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0009931 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 18.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.5 8.3 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.4 14.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.4 6.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.4 10.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.3 2.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.3 2.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 2.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 11.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 9.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.1 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 3.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 9.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 2.4 PID LKB1 PATHWAY LKB1 signaling events
0.1 6.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 1.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.6 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 11.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
1.7 13.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.2 2.4 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
1.0 7.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.7 14.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.7 14.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.5 16.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.5 8.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.4 2.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.4 2.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.3 2.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.2 10.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 1.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 1.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.2 1.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.2 2.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2 2.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 1.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 3.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.9 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 1.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 3.4 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.1 1.8 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 5.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 0.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.0 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements