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Results for si:ch211-69l10.4+tbx15_tbx4_tbx1_mgaa

Z-value: 2.71

Motif logo

Transcription factors associated with si:ch211-69l10.4+tbx15_tbx4_tbx1_mgaa

Gene Symbol Gene ID Gene Info
ENSDARG00000002582 T-box transcription factor 15
ENSDARG00000098036 si_ch211-69l10.4
ENSDARG00000030058 T-box transcription factor 4
ENSDARG00000031891 T-box transcription factor 1
ENSDARG00000078784 MAX dimerization protein MGA a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
mgaadr10_dc_chr17_+_10410393_104104960.758.5e-04Click!
tbx1dr10_dc_chr5_+_14703190_147032280.702.5e-03Click!
tbx15dr10_dc_chr9_-_21257082_212571370.458.3e-02Click!
tbx4dr10_dc_chr15_+_27454643_274546650.401.2e-01Click!

Activity profile of si:ch211-69l10.4+tbx15_tbx4_tbx1_mgaa motif

Sorted Z-values of si:ch211-69l10.4+tbx15_tbx4_tbx1_mgaa motif

Network of associatons between targets according to the STRING database.

First level regulatory network of si:ch211-69l10.4+tbx15_tbx4_tbx1_mgaa

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr23_+_23305483 17.53 ENSDART00000126479
pleckstrin homology domain containing, family N member 1
chr1_-_11439671 12.63 ENSDART00000164817
microsomal triglyceride transfer protein
chr17_+_26946957 9.56 ENSDART00000114215
grainyhead-like transcription factor 3
chr17_-_42293039 9.47 ENSDART00000014296
forkhead box A2
chr21_-_3548719 9.33 ENSDART00000137844
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr5_+_26925238 8.43 ENSDART00000051491
secreted frizzled-related protein 1a
chr11_-_11591394 7.89 ENSDART00000142208
zgc:110712
chr7_+_6814828 7.38 ENSDART00000001649
actinin alpha 3b
chr19_-_7501777 7.02 ENSDART00000081741
RAB25, member RAS oncogene family a
chr19_+_14197118 6.95 ENSDART00000166230
trophoblast glycoprotein a
chr25_-_10919875 6.88 ENSDART00000099572
mesoderm posterior ab
chr14_-_5510157 6.48 ENSDART00000131820
Kazal-type serine peptidase inhibitor domain 2
chr6_+_56157608 6.47 ENSDART00000149665
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr11_-_11925832 6.17

chr14_-_25879853 6.15 ENSDART00000014149
FAT atypical cadherin 2
KN150078v1_+_1387 5.79

chr8_-_38168395 5.54 ENSDART00000155189
PDZ and LIM domain 2 (mystique)
chr3_-_44113070 5.23 ENSDART00000160717
zinc finger protein 750
chr22_-_15567180 5.23 ENSDART00000123125
tropomyosin 4a
chr16_-_26803204 5.21 ENSDART00000162665
epithelial splicing regulatory protein 1
chr1_-_51862897 5.16 ENSDART00000136469
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr15_+_42440802 5.00 ENSDART00000089694
T-cell lymphoma invasion and metastasis 1b
chr25_+_31547276 4.98 ENSDART00000090727
dual oxidase
chr24_+_19374200 4.91 ENSDART00000056081
ENSDART00000027022
sulfatase 1
chr8_-_22486746 4.67 ENSDART00000101616
si:ch211-261n11.5
chr24_+_19374099 4.45 ENSDART00000056081
ENSDART00000027022
sulfatase 1
chr2_-_53772219 4.31 ENSDART00000037557
anti-dorsalizing morphogenic protein
chr15_+_42440952 4.27 ENSDART00000089694
T-cell lymphoma invasion and metastasis 1b
chr23_-_39956151 4.26 ENSDART00000115330
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr7_+_15065241 4.24 ENSDART00000045385
mesoderm posterior ba
chr4_+_9027862 4.23 ENSDART00000102893
aldehyde dehydrogenase 1 family, member L2
chr20_+_17840364 4.22 ENSDART00000024627
cadherin 2, type 1, N-cadherin (neuronal)
chr7_+_15081529 4.21 ENSDART00000006018
mesoderm posterior aa
chr8_-_14142049 4.18 ENSDART00000126432
ras homolog gene family, member Aa
chr14_+_46419051 4.09 ENSDART00000112377
microtubule-associated protein 1 light chain 3 gamma, like
chr3_-_60973097 4.02 ENSDART00000055062
parvalbumin 1
chr6_+_17959219 3.96 ENSDART00000026448
envoplakin a
chr14_+_15698814 3.80

chr3_+_13043951 3.77

chr13_+_14845093 3.77 ENSDART00000011520
notochord homeobox
chr14_-_5510256 3.77 ENSDART00000131820
Kazal-type serine peptidase inhibitor domain 2
chr24_-_18775146 3.76 ENSDART00000144244
carboxypeptidase A6
chr15_-_20297270 3.74 ENSDART00000123910
protein phosphatase 1, regulatory (inhibitor) subunit 14Ab
chr7_-_52142689 3.71 ENSDART00000110265
myocardial zonula adherens protein
chr4_-_11582061 3.62 ENSDART00000049066
neuroepithelial cell transforming 1
chr8_-_4451417 3.58 ENSDART00000141915
si:ch211-166a6.5
chr3_-_23513177 3.55 ENSDART00000078425
even-skipped-like1
chr14_-_32404076 3.52 ENSDART00000075617
SRY (sex determining region Y)-box 3
chr25_+_7660590 3.51 ENSDART00000155016
diacylglycerol kinase, zeta b
chr7_-_58523645 3.51

chr2_-_47578695 3.36 ENSDART00000014350
ENSDART00000038828
paired box 3a
chr20_-_43826667 3.30 ENSDART00000100637
Mix paired-like homeobox
chr14_-_6901415 3.27 ENSDART00000167994
ENSDART00000166532
storkhead box 2b
chr7_-_44332679 3.26 ENSDART00000073745
CKLF-like MARVEL transmembrane domain containing 4
chr3_-_25683205 3.24 ENSDART00000169706
netrin 1b
chr23_+_28656263 3.24 ENSDART00000020296
neural adhesion molecule L1.2
chr3_+_42380497 3.20 ENSDART00000163579
si:dkey-43p13.5
chr6_+_30441419 3.17

chr25_-_31547164 3.11 ENSDART00000110180
dual oxidase 2
chr20_-_19646761 3.08

chr22_-_3134876 3.08 ENSDART00000159580
lamin B2
chr10_-_26468280 3.05 ENSDART00000128894
dachsous cadherin-related 1b
chr10_-_44619155 3.02 ENSDART00000085556
huntingtin interacting protein 1 related a
chr5_+_37053530 3.00 ENSDART00000161051
spectrin, beta, non-erythrocytic 2
chr19_-_35642440 2.99 ENSDART00000167853
ENSDART00000054274
microtubule-actin crosslinking factor 1a
chr17_+_1058137 2.95

chr17_+_16067769 2.95 ENSDART00000155292
si:ch73-204p21.2
chr22_+_1283662 2.93 ENSDART00000124161
si:ch73-138e16.5
chr15_-_30975632 2.88

chr22_-_37468331 2.85 ENSDART00000160940
SOX2 overlapping transcript exon 1
chr18_+_7632469 2.81 ENSDART00000136313
si:dkeyp-1h4.6
chr17_-_42292997 2.78 ENSDART00000014296
forkhead box A2
KN150214v1_-_155944 2.76

chr3_-_19050721 2.75 ENSDART00000131503
regulatory factor X, 1a (influences HLA class II expression)
chr13_-_33696425 2.73 ENSDART00000143703
fibronectin leucine rich transmembrane 3
chr15_-_1625846 2.66 ENSDART00000081875
nanor
chr11_-_1409262 2.65 ENSDART00000155269
phosphatase and actin regulator 3b
chr9_-_22140954 2.57 ENSDART00000146528
LIM domain 7a
chr19_-_23037220 2.55 ENSDART00000090669
plectin a
chr13_+_27102308 2.55 ENSDART00000145901
Ras and Rab interactor 2
chr25_-_10930008 2.49 ENSDART00000156846
mesoderm posterior bb
chr13_+_32013916 2.46 ENSDART00000020270
odd-skipped related transciption factor 1
chr15_+_32853646 2.38 ENSDART00000167515
periostin, osteoblast specific factor b
chr22_-_120677 2.37

chr8_+_32604349 2.37 ENSDART00000126833
hemicentin 2
chr13_+_32894285 2.30 ENSDART00000057377
arginase 2
chr14_-_2728708 2.30 ENSDART00000031211
bicaudal C homolog 2
chr13_+_22165699 2.25

chr17_-_31147256 2.24 ENSDART00000055754
protein kinase domain containing, cytoplasmic b
chr14_+_5078937 2.22 ENSDART00000031508
ladybird homeobox 2
chr13_+_18401965 2.17 ENSDART00000136024
finTRIM family, member 14-like
chr10_-_43711606 2.14 ENSDART00000170891
si:ch73-215f7.1
chr22_-_4414254 2.12 ENSDART00000114465
zgc:195170
chr2_+_20118917 2.11 ENSDART00000038648
polypyrimidine tract binding protein 2b
chr12_-_34786844 2.11 ENSDART00000027379
BRD4 interacting chromatin remodeling complex associated protein like
chr23_+_20522512 2.10 ENSDART00000137294
solute carrier family 35 (GDP-fucose transporter), member C2
chr1_+_50835265 2.09 ENSDART00000162226
Meis homeobox 1 a
chr12_-_43917936 2.09 ENSDART00000159423
forkhead box i1
chr13_+_27102377 2.08 ENSDART00000138043
Ras and Rab interactor 2
chr1_-_51863187 2.07 ENSDART00000004233
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr11_+_23695123 2.00 ENSDART00000000486
contactin 2
chr4_+_899111 1.98 ENSDART00000103631
ripply transcriptional repressor 2
chr2_-_42384993 1.92 ENSDART00000141358
apolipoprotein M
chr9_+_33167554 1.88 ENSDART00000007630
nescient helix loop helix 2
chr13_+_22350043 1.88 ENSDART00000136863
LIM domain binding 3a
chr19_-_791149 1.86 ENSDART00000151782
ENSDART00000037515
misato 1, mitochondrial distribution and morphology regulator
chr24_-_32750010 1.85 ENSDART00000038364
carbonic anhydrase II
chr16_-_26803131 1.85 ENSDART00000103431
epithelial splicing regulatory protein 1
chr16_+_40351223 1.84 ENSDART00000058578
R-spondin 3
chr12_-_31342432 1.83 ENSDART00000148603
acyl-CoA synthetase long-chain family member 5
chr4_-_19027117 1.80 ENSDART00000166160
si:dkey-31f5.11
chr19_-_32175977 1.80

chr10_+_18994733 1.79 ENSDART00000146517
dihydropyrimidinase-like 2b
chr19_+_47720261 1.74 ENSDART00000136647
exostoses (multiple) 1c
chr13_+_22165657 1.74

chr20_-_54645287 1.74 ENSDART00000153389
YY1 transcription factor b
chr7_-_18256512 1.71 ENSDART00000173539
regulator of G protein signaling 12a
chr3_+_43010408 1.71 ENSDART00000169061
ENSDARG00000099842
chr17_-_8155740 1.71 ENSDART00000064678
lefty2
chr11_-_30105047 1.64 ENSDART00000030794
transmembrane protein 169a
chr6_-_3763870 1.62 ENSDART00000171804
tousled-like kinase 1b
chr1_-_18695214 1.62

chr19_+_14197020 1.61 ENSDART00000166230
trophoblast glycoprotein a
chr13_-_36409205 1.61 ENSDART00000043312
serine/arginine-rich splicing factor 5a
chr25_-_12691849 1.59 ENSDART00000158551
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr17_-_10682357 1.54 ENSDART00000064597
lectin, galactoside binding soluble 3b
chr9_-_22141138 1.54 ENSDART00000146528
LIM domain 7a
chr10_-_4979688 1.52 ENSDART00000093228
methionine adenosyltransferase II, alpha-like
chr20_-_8122838 1.49 ENSDART00000113993
si:ch211-232i5.1
chr17_-_20264762 1.49

chr7_+_29969936 1.48 ENSDART00000109243
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4Bb
chr13_+_30190977 1.47

chr17_+_38307512 1.45 ENSDART00000005296
NK2 transcription factor related, locus 9 (Drosophila)
chr8_-_6875110 1.45 ENSDART00000014915
ankyrin repeat and SOCS box containing 6
chr23_+_22763861 1.41

chr16_-_29502741 1.40 ENSDART00000148405
si:ch211-113g11.6
chr10_+_4717800 1.40 ENSDART00000161789
paralemmin 2
chr15_-_104331 1.39 ENSDART00000164323
ENSDART00000161218
cytochrome P450, family 2, subfamily Y, polypeptide 3
chr12_+_25509394 1.39 ENSDART00000077157
SIX homeobox 3b
chr13_+_32894092 1.38 ENSDART00000057377
arginase 2
chr11_+_23694891 1.38 ENSDART00000000486
contactin 2
chr25_-_31218193 1.38 ENSDART00000170673
ENSDART00000166930
laminin, beta 1a
chr16_-_41553835 1.37 ENSDART00000029492
CKLF-like MARVEL transmembrane domain containing 7
chr11_-_26595578 1.37 ENSDART00000153519
IQ motif and Sec7 domain 1b
chr22_-_12130441 1.36 ENSDART00000146785
transmembrane protein 163b
chr21_+_25729090 1.35 ENSDART00000021664
claudin b
chr15_+_40707917 1.33 ENSDART00000154187
ENSDART00000042082
FAT atypical cadherin 3a
chr23_-_24240728 1.33 ENSDART00000113598
Rho guanine nucleotide exchange factor (GEF) 19
chr5_-_44243476 1.33 ENSDART00000161408
fructose-1,6-bisphosphatase 1a
chr10_-_31838886 1.31 ENSDART00000128839
fasciculation and elongation protein zeta 1 (zygin I)
chr8_-_28415750 1.31 ENSDART00000062702
CCAAT/enhancer binding protein (C/EBP), beta
chr9_-_43072092 1.27 ENSDART00000125953
titin, tandem duplicate 1
chr24_-_6129575 1.26 ENSDART00000021609
glutamate decarboxylase 2
chr19_-_5416317 1.26 ENSDART00000010373
keratin, type 1, gene 19d
chr5_+_51992974 1.25 ENSDART00000170341
amyloid beta (A4) precursor protein-binding, family A, member 1a
chr20_+_316191 1.25 ENSDART00000104807
si:dkey-119m7.4
chr10_-_43711513 1.25 ENSDART00000170891
si:ch73-215f7.1
chr12_+_29121368 1.22 ENSDART00000006505
mix-type homeobox gene 2
chr25_+_7147666 1.22 ENSDART00000104712
high mobility group 20A
chr22_+_16471319 1.22 ENSDART00000014330
immediate early response 5
chr3_+_34010958 1.21 ENSDART00000131802
si:dkey-204f11.64
chr17_-_15490279 1.20 ENSDART00000156905
ENSDART00000161374
ENSDART00000080661
si:ch211-266g18.10
chr15_-_41288480 1.20 ENSDART00000155359
single-pass membrane protein with coiled-coil domains 4
chr5_+_34022151 1.19 ENSDART00000141338
ectodermal-neural cortex 1
chr14_-_32704626 1.18 ENSDART00000170626
kinase insert domain receptor like
chr2_+_56946287 1.17

chr19_-_5851328 1.15 ENSDART00000133106
si:ch211-264f5.6
chr14_+_33382973 1.14 ENSDART00000132488
apelin
chr2_+_56946090 1.14

chr22_-_14103803 1.13 ENSDART00000062902
ENSDARG00000042857
chr25_-_32344881 1.12 ENSDART00000012862
ISL LIM homeobox 2a
chr9_+_17431036 1.11 ENSDART00000140852
regulator of cell cycle
chr6_+_30447235 1.11

chr20_-_47576935 1.10 ENSDART00000067776
RAB10, member RAS oncogene family
chr8_-_19166630 1.09

chr1_+_36476280 1.08 ENSDART00000043855
doublecortin-like kinase 2a
chr10_-_31619761 1.06 ENSDART00000023575
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr21_-_2191847 1.06 ENSDART00000159315
si:dkey-50i6.5
chr23_+_23559246 1.06 ENSDART00000172214
agrin
chr11_-_6051096 1.04 ENSDART00000147761
vessel-specific 1
chr16_+_46728964 1.03 ENSDART00000163571
RAB25, member RAS oncogene family b
chr10_-_44619365 1.03 ENSDART00000085556
huntingtin interacting protein 1 related a
chr18_+_18874077 1.03 ENSDART00000091094
plasmolipin
chr22_-_30986222 1.03 ENSDART00000133335
si:dkey-49n23.1
chr11_+_1601946 1.03 ENSDART00000154967
low density lipoprotein receptor-related protein 1Aa
chr2_-_53771952 1.02 ENSDART00000037557
anti-dorsalizing morphogenic protein
chr7_+_32097831 1.01 ENSDART00000169588
leucine rich repeat containing G protein-coupled receptor 4
chr20_-_23949621 1.01

chr1_-_8968543 1.00 ENSDART00000126877
ENSDART00000123773
ENSDART00000126996
UDP glucuronosyltransferase 5 family, polypeptide B1
UDP glucuronosyltransferase 5 family, polypeptide B3
chr21_+_26690161 0.99 ENSDART00000065392
calmodulin 3b (phosphorylase kinase, delta)
chr8_+_20125687 0.99 ENSDART00000124809
acyl-CoA synthetase bubblegum family member 2
chr25_-_17483202 0.99 ENSDART00000073684
matrix metallopeptidase 15a
chr17_-_38494727 0.98 ENSDART00000085438
ribosomal protein S6 kinase, polypeptide 5
chr25_+_35777308 0.97 ENSDART00000073452
si:ch211-113a14.12
chr17_+_31722419 0.96 ENSDART00000155073
Rho GTPase activating protein 5
chr15_-_23711689 0.96 ENSDART00000128644
creatine kinase, muscle b
chr7_+_60054116 0.96 ENSDART00000145201
protein phosphatase 1, regulatory (inhibitor) subunit 14Bb
chr15_-_37973812 0.95 ENSDART00000122439
si:dkey-238d18.4
chr11_+_27970922 0.95 ENSDART00000169360
ENSDART00000043756
eph receptor B2b
chr3_-_23539034 0.94

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 17.6 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
2.7 10.9 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
2.7 5.3 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
2.6 13.0 GO:0032289 central nervous system myelin formation(GO:0032289)
2.3 9.4 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
1.9 3.8 GO:0048322 axial mesodermal cell differentiation(GO:0048321) axial mesodermal cell fate commitment(GO:0048322) axial mesodermal cell fate specification(GO:0048327)
1.7 10.4 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
1.7 5.0 GO:0042554 superoxide anion generation(GO:0042554)
1.4 4.2 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
1.3 3.8 GO:0060832 oocyte animal/vegetal axis specification(GO:0060832)
1.1 10.2 GO:0060325 face morphogenesis(GO:0060325)
0.9 3.7 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.8 3.4 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.8 4.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.8 8.9 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.8 2.4 GO:0043589 skin morphogenesis(GO:0043589)
0.7 2.2 GO:1904105 positive regulation of convergent extension involved in gastrulation(GO:1904105)
0.7 3.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.7 2.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.6 3.2 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.6 2.5 GO:0035776 pronephric proximal tubule development(GO:0035776)
0.6 1.8 GO:0015670 carbon dioxide transport(GO:0015670)
0.6 1.8 GO:1902001 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) regulation of organic acid transport(GO:0032890) positive regulation of organic acid transport(GO:0032892) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transport(GO:1903793) regulation of anion transmembrane transport(GO:1903959) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.6 4.2 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.5 1.5 GO:0048245 eosinophil chemotaxis(GO:0048245) eosinophil migration(GO:0072677)
0.5 3.1 GO:0007343 egg activation(GO:0007343)
0.5 1.9 GO:0048311 mitochondrion distribution(GO:0048311)
0.5 0.5 GO:0006531 aspartate metabolic process(GO:0006531)
0.5 1.4 GO:0055016 hypochord development(GO:0055016)
0.4 6.5 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.4 1.3 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.4 4.0 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.4 3.5 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.4 1.1 GO:0042756 drinking behavior(GO:0042756)
0.4 3.4 GO:0050936 xanthophore differentiation(GO:0050936)
0.3 9.4 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.3 1.3 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.3 10.4 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.3 4.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 4.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.3 1.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.3 0.8 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.3 0.8 GO:0030818 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350) negative regulation of purine nucleotide biosynthetic process(GO:1900372)
0.3 3.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 1.1 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.2 1.7 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.2 4.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 4.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 0.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.2 0.4 GO:0051965 regulation of synapse assembly(GO:0051963) positive regulation of synapse assembly(GO:0051965)
0.2 1.3 GO:0048769 sarcomerogenesis(GO:0048769)
0.2 4.0 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.2 0.7 GO:0070296 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) sarcoplasmic reticulum calcium ion transport(GO:0070296) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.2 0.5 GO:1903385 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.2 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 0.8 GO:0099640 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) axo-dendritic protein transport(GO:0099640)
0.2 1.8 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.2 1.1 GO:0006970 response to osmotic stress(GO:0006970)
0.1 0.7 GO:0033292 T-tubule organization(GO:0033292)
0.1 4.8 GO:0048484 enteric nervous system development(GO:0048484)
0.1 1.8 GO:0016203 muscle attachment(GO:0016203)
0.1 1.0 GO:0016572 histone phosphorylation(GO:0016572)
0.1 14.4 GO:0001558 regulation of cell growth(GO:0001558)
0.1 0.8 GO:0090303 positive regulation of wound healing(GO:0090303)
0.1 1.7 GO:0003128 heart field specification(GO:0003128) specification of organ identity(GO:0010092)
0.1 0.8 GO:0030104 water homeostasis(GO:0030104)
0.1 3.5 GO:0043049 otic placode formation(GO:0043049)
0.1 1.0 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.1 0.6 GO:1900028 negative regulation of Rac protein signal transduction(GO:0035021) wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.1 0.7 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.1 0.1 GO:0048320 axial mesoderm formation(GO:0048320)
0.1 0.9 GO:0042694 muscle cell fate specification(GO:0042694)
0.1 2.3 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.3 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 0.8 GO:0070199 establishment of protein localization to chromosome(GO:0070199) establishment of protein localization to chromatin(GO:0071169)
0.1 0.9 GO:0086003 cardiac muscle cell contraction(GO:0086003)
0.1 1.2 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 1.2 GO:0030878 thyroid gland development(GO:0030878)
0.1 1.4 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.6 GO:0072378 platelet aggregation(GO:0070527) blood coagulation, fibrin clot formation(GO:0072378)
0.1 0.3 GO:0018364 peptidyl-glutamine methylation(GO:0018364) rRNA (guanine-N7)-methylation(GO:0070476)
0.1 1.0 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 0.4 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1 0.5 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.1 3.1 GO:0030834 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) actin filament capping(GO:0051693)
0.1 0.6 GO:0046549 retinal cone cell development(GO:0046549)
0.1 0.2 GO:0098900 regulation of action potential(GO:0098900)
0.1 1.0 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 0.4 GO:0030033 microvillus assembly(GO:0030033) microvillus organization(GO:0032528)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 1.6 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.1 0.9 GO:0044030 regulation of DNA methylation(GO:0044030)
0.1 0.4 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.3 GO:0034650 cortisol metabolic process(GO:0034650)
0.1 6.6 GO:0008544 epidermis development(GO:0008544)
0.1 1.3 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 0.3 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.1 0.3 GO:0051177 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.4 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.1 0.3 GO:2000379 protein import into mitochondrial inner membrane(GO:0045039) positive regulation of reactive oxygen species metabolic process(GO:2000379)
0.1 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 1.7 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1 0.3 GO:0006558 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1 0.2 GO:0090242 mesodermal-endodermal cell signaling(GO:0003131) response to vitamin A(GO:0033189) cellular response to vitamin A(GO:0071299) retinoic acid receptor signaling pathway involved in somitogenesis(GO:0090242)
0.1 0.7 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.6 GO:0043687 post-translational protein modification(GO:0043687)
0.1 0.9 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.0 0.6 GO:0045332 phospholipid translocation(GO:0045332)
0.0 5.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.6 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.0 0.3 GO:0003207 cardiac chamber formation(GO:0003207)
0.0 1.0 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.7 GO:0071696 ectodermal placode development(GO:0071696)
0.0 0.9 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.4 GO:0031577 mitotic spindle assembly checkpoint(GO:0007094) spindle checkpoint(GO:0031577) negative regulation of mitotic metaphase/anaphase transition(GO:0045841) spindle assembly checkpoint(GO:0071173) mitotic spindle checkpoint(GO:0071174)
0.0 0.3 GO:0060061 developmental induction(GO:0031128) Spemann organizer formation(GO:0060061)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.8 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 1.0 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 6.0 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.2 GO:0099565 chemical synaptic transmission, postsynaptic(GO:0099565)
0.0 0.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.4 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.0 0.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.7 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.9 GO:0001706 endoderm formation(GO:0001706)
0.0 1.1 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.0 2.3 GO:0031101 fin regeneration(GO:0031101)
0.0 0.2 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.0 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.8 GO:0060349 bone morphogenesis(GO:0060349)
0.0 0.1 GO:0021846 cell proliferation in forebrain(GO:0021846)
0.0 0.9 GO:0042246 tissue regeneration(GO:0042246)
0.0 2.1 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.0 2.4 GO:0060047 heart contraction(GO:0060047)
0.0 0.3 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)
0.0 0.4 GO:0039021 pronephric glomerulus development(GO:0039021)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.9 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.2 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.8 GO:0016358 dendrite development(GO:0016358)
0.0 1.7 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.0 1.4 GO:0030155 regulation of cell adhesion(GO:0030155)
0.0 2.2 GO:0048701 embryonic cranial skeleton morphogenesis(GO:0048701)
0.0 3.3 GO:0061061 muscle structure development(GO:0061061)
0.0 0.5 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 0.2 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.4 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.2 GO:0032438 melanosome organization(GO:0032438)
0.0 0.6 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.2 GO:0008361 regulation of cell size(GO:0008361)
0.0 0.8 GO:0006865 amino acid transport(GO:0006865)
0.0 0.6 GO:0001947 heart looping(GO:0001947)
0.0 0.8 GO:0001666 response to hypoxia(GO:0001666)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.0 GO:0043020 NADPH oxidase complex(GO:0043020)
1.3 10.3 GO:0005614 interstitial matrix(GO:0005614)
0.9 3.8 GO:0032019 mitochondrial cloud(GO:0032019)
0.6 3.0 GO:0008091 spectrin(GO:0008091)
0.4 4.4 GO:0030056 hemidesmosome(GO:0030056)
0.4 4.2 GO:0014704 intercalated disc(GO:0014704)
0.3 1.5 GO:0001772 immunological synapse(GO:0001772)
0.2 7.3 GO:0031941 filamentous actin(GO:0031941)
0.2 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.2 4.1 GO:0000421 autophagosome membrane(GO:0000421)
0.1 9.8 GO:0005882 intermediate filament(GO:0005882)
0.1 1.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 6.4 GO:0005604 basement membrane(GO:0005604)
0.1 8.5 GO:0005795 Golgi stack(GO:0005795)
0.1 2.8 GO:0016342 catenin complex(GO:0016342)
0.1 1.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 1.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.8 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.3 GO:0016460 myosin II complex(GO:0016460)
0.1 3.6 GO:0005581 collagen trimer(GO:0005581)
0.1 4.5 GO:0005884 actin filament(GO:0005884)
0.1 1.5 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.3 GO:1990130 Iml1 complex(GO:1990130)
0.1 4.2 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 2.9 GO:0030425 dendrite(GO:0030425)
0.1 0.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 8.4 GO:0043005 neuron projection(GO:0043005)
0.1 0.4 GO:0033503 HULC complex(GO:0033503)
0.1 28.9 GO:0005615 extracellular space(GO:0005615)
0.1 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 0.3 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 0.7 GO:0030315 T-tubule(GO:0030315)
0.1 4.4 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.0 1.6 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 5.8 GO:0005912 adherens junction(GO:0005912)
0.0 2.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 17.0 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 0.4 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.9 GO:0005861 troponin complex(GO:0005861)
0.0 0.4 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.6 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.7 GO:0044306 axon terminus(GO:0043679) neuron projection terminus(GO:0044306)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.5 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.7 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 1.5 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.5 GO:0043204 perikaryon(GO:0043204)
0.0 1.8 GO:0008021 synaptic vesicle(GO:0008021)
0.0 6.2 GO:0045202 synapse(GO:0045202)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 1.0 GO:0031012 extracellular matrix(GO:0031012)
0.0 3.5 GO:0005576 extracellular region(GO:0005576)
0.0 0.4 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 8.2 GO:0005739 mitochondrion(GO:0005739)
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)
0.0 3.7 GO:0000785 chromatin(GO:0000785)
0.0 0.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 17.6 GO:1901612 cardiolipin binding(GO:1901612)
1.7 5.0 GO:0016175 NAD(P)H oxidase activity(GO:0016174) superoxide-generating NADPH oxidase activity(GO:0016175)
0.9 9.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.8 4.0 GO:0019215 intermediate filament binding(GO:0019215)
0.8 3.0 GO:0016936 galactoside binding(GO:0016936)
0.7 9.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.7 4.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.4 1.7 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.4 9.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.4 4.4 GO:0030506 ankyrin binding(GO:0030506)
0.4 4.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 3.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.3 7.3 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.3 4.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.3 3.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.3 1.8 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.3 1.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.2 1.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 0.6 GO:0019960 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 4.7 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.2 0.8 GO:0099528 G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.2 1.1 GO:0031704 apelin receptor binding(GO:0031704)
0.2 0.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 23.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2 0.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 1.8 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 8.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.2 1.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 0.5 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 7.0 GO:0045296 cadherin binding(GO:0045296)
0.1 0.3 GO:0070402 NADPH binding(GO:0070402)
0.1 1.3 GO:0043236 laminin binding(GO:0043236)
0.1 0.7 GO:0060182 apelin receptor activity(GO:0060182)
0.1 1.0 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.1 0.6 GO:0015665 alcohol transmembrane transporter activity(GO:0015665)
0.1 0.8 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.9 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.1 2.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.7 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.1 0.9 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.3 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 1.0 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 1.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.0 GO:0016405 CoA-ligase activity(GO:0016405)
0.1 0.4 GO:0016842 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) amidine-lyase activity(GO:0016842)
0.1 11.9 GO:0019904 protein domain specific binding(GO:0019904)
0.1 3.3 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 0.4 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.1 0.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 2.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.3 GO:0032034 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.1 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 3.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.3 GO:0050308 carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.1 5.4 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 0.6 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.7 GO:0031628 opioid receptor binding(GO:0031628)
0.1 3.3 GO:0045499 semaphorin receptor binding(GO:0030215) chemorepellent activity(GO:0045499)
0.1 0.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.9 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 5.3 GO:0008083 growth factor activity(GO:0008083)
0.1 3.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.6 GO:0017046 peptide hormone binding(GO:0017046)
0.0 25.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 9.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.5 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0043176 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.0 0.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 2.8 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 15.3 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.2 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 2.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 9.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 1.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0051959 dynein intermediate chain binding(GO:0045505) dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 4.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.6 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.2 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 4.4 GO:0051015 actin filament binding(GO:0051015)
0.0 0.8 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.5 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 5.2 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.5 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 13.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 1.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 6.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 6.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 4.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.5 NABA COLLAGENS Genes encoding collagen proteins
0.1 8.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 5.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 2.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.8 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 12.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.5 0.9 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.4 3.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 1.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 1.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 4.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.2 4.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.3 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 2.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.0 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.6 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases