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Results for si:dkey-229b18.3+snai2

Z-value: 1.77

Activity profile of si:dkey-229b18.3+snai2 motif

Sorted Z-values of si:dkey-229b18.3+snai2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of si:dkey-229b18.3+snai2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_-_28444272 5.89 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr7_-_55346967 5.64 ENSDART00000135304
pabpn1l
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr20_-_42095643 5.35 ENSDART00000100967
si:dkeyp-114g9.1
si:dkeyp-114g9.1
chr9_-_28444024 4.61 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr1_-_48876924 4.53 ENSDART00000143474
zp3c
zona pellucida glycoprotein 3c
chr17_+_699708 4.25 ENSDART00000165144
siva1
SIVA1, apoptosis-inducing factor
chr17_-_25313024 4.22 ENSDART00000082324
zpcx
zona pellucida protein C
chr12_-_2834771 4.09 ENSDART00000114854
ENSDART00000163759
zdhhc16b
zinc finger, DHHC-type containing 16b
chr20_-_43826667 4.03 ENSDART00000100637
mixl1
Mix paired-like homeobox
chr11_+_29290515 4.01 ENSDART00000103388
wu:fi42e03
wu:fi42e03
chr14_+_29945327 3.74 ENSDART00000173090
mtus1a
microtubule associated tumor suppressor 1a
chr1_+_41762057 3.59 ENSDART00000137609
ctnna2
catenin (cadherin-associated protein), alpha 2
KN150589v1_-_5209 3.50 ENSDART00000157761
ENSDART00000157531
elovl7b
ELOVL fatty acid elongase 7b
chr12_-_2834814 3.20 ENSDART00000114854
ENSDART00000163759
zdhhc16b
zinc finger, DHHC-type containing 16b
chr24_-_38195383 3.16 ENSDART00000056381
crp2
C-reactive protein 2
chr20_-_43846604 3.15 ENSDART00000150078
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr7_+_26730804 3.15

chr7_-_51497945 3.15 ENSDART00000054591
bmp15
bone morphogenetic protein 15
chr22_-_38321005 2.89 ENSDART00000015117
elavl2
ELAV like neuron-specific RNA binding protein 2
chr14_+_14850200 2.77 ENSDART00000167966
zgc:158852
zgc:158852
chr5_-_32636372 2.74 ENSDART00000085512
ENSDART00000144694
kank1b
KN motif and ankyrin repeat domains 1b
chr21_-_804453 2.68

chr20_-_23527234 2.67 ENSDART00000004625
zar1
zygote arrest 1
chr9_-_28443972 2.63 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr9_+_30564831 2.61

chr22_-_10562118 2.56 ENSDART00000105846
si:dkey-42i9.8
si:dkey-42i9.8
chr19_-_48327666 2.56

chr3_-_55252907 2.53 ENSDART00000108995
tex2
testis expressed 2
chr18_+_5616001 2.52 ENSDART00000163629
dut
deoxyuridine triphosphatase
chr7_-_73890499 2.44 ENSDART00000164992
rbpms
RNA binding protein with multiple splicing
chr7_-_69576406 2.44

chr15_-_1625846 2.40 ENSDART00000081875
nnr
nanor
chr2_+_37312637 2.32 ENSDART00000056519
gpr160
G protein-coupled receptor 160
chr2_+_10040130 2.26 ENSDART00000139639
anxa13l
annexin A13, like
chr9_-_28444210 2.26 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr3_-_34398743 2.16 ENSDART00000023039
sept9a
septin 9a
chr20_-_43846553 2.15 ENSDART00000150078
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr7_-_52847458 2.13 ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr23_+_15015854 2.10 ENSDART00000054915
ENSDART00000137410
exosc10
exosome component 10
chr7_-_69576270 2.08

chr10_+_6339059 2.06 ENSDART00000160813
tpm2
tropomyosin 2 (beta)
chr19_+_791656 2.04 ENSDART00000138406
tmem79a
transmembrane protein 79a
chr23_+_6610443 2.02 ENSDART00000005373
spo11
SPO11 meiotic protein covalently bound to DSB
chr18_+_45669615 2.02 ENSDART00000150973
prrg4
proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
chr20_-_3220475 1.95 ENSDART00000123331
spint1b
serine peptidase inhibitor, Kunitz type 1 b
chr12_+_20569659 1.94 ENSDART00000141804
st6galnac1.2
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, tandem duplicate 2
chr14_-_21320696 1.93 ENSDART00000043162
reep2
receptor accessory protein 2
chr1_+_23778514 1.92 ENSDART00000176581
fam160a1a
family with sequence similarity 160, member A1a
chr24_-_36721857 1.90

chr7_-_19116999 1.88 ENSDART00000165680
ntn4
netrin 4
chr22_+_22413803 1.85 ENSDART00000147825
kif14
kinesin family member 14
chr1_+_23778481 1.85 ENSDART00000176581
fam160a1a
family with sequence similarity 160, member A1a
chr17_+_25828037 1.84

KN150455v1_-_14200 1.84

chr16_+_24046472 1.84

chr3_-_25142506 1.80 ENSDART00000145315
ddx5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr10_-_109097 1.79 ENSDART00000127228
ttc3
tetratricopeptide repeat domain 3
chr13_+_34563757 1.79 ENSDART00000133661
tasp1
taspase, threonine aspartase, 1
chr25_-_12148502 1.79

chr3_-_25142301 1.77 ENSDART00000145315
ddx5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr12_-_7201358 1.76 ENSDART00000048866
ipmkb
inositol polyphosphate multikinase b
chr23_+_116397 1.75

chr20_+_49332270 1.75

chr10_+_37229202 1.75 ENSDART00000136510
ksr1a
kinase suppressor of ras 1a
chr11_-_25615491 1.73 ENSDART00000145655
tmem51b
transmembrane protein 51b
chr2_+_44659334 1.72 ENSDART00000155017
pask
PAS domain containing serine/threonine kinase
chr12_+_22551105 1.72 ENSDART00000123808
ENSDART00000159864
cdca9
cell division cycle associated 9
chr20_+_21369047 1.70 ENSDART00000090016
nudt14
nudix (nucleoside diphosphate linked moiety X)-type motif 14
chr14_-_14353451 1.68 ENSDART00000170355
ENSDART00000159888
nsdhl
NAD(P) dependent steroid dehydrogenase-like
chr22_-_26504565 1.66 ENSDART00000087623
zgc:194330
zgc:194330
chr13_+_6091158 1.64 ENSDART00000025910
apmap
adipocyte plasma membrane associated protein
chr7_+_20651600 1.63 ENSDART00000129161
wrap53
WD repeat containing, antisense to TP53
chr3_-_25142556 1.62 ENSDART00000145315
ddx5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr5_-_18458903 1.62 ENSDART00000145210
ankle2
ankyrin repeat and LEM domain containing 2
chr6_-_21756764 1.60 ENSDART00000167937
p4hb
prolyl 4-hydroxylase, beta polypeptide
chr2_-_41598080 1.59 ENSDART00000178357
ENSDART00000176801
ENSDART00000177840
CU302321.2
ENSDARG00000107739
chr10_+_6339177 1.58 ENSDART00000160813
tpm2
tropomyosin 2 (beta)
chr10_-_25808033 1.54 ENSDART00000134176
postna
periostin, osteoblast specific factor a
chr14_+_971438 1.53 ENSDART00000161487
si:ch73-308l14.2
si:ch73-308l14.2
chr2_+_19588034 1.53 ENSDART00000163875
cc2d1b
coiled-coil and C2 domain containing 1B
chr23_+_26099718 1.52 ENSDART00000141553
pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr25_+_31979838 1.46 ENSDART00000012600
galk2
galactokinase 2
chr5_+_6476950 1.44 ENSDART00000176805
CABZ01112925.1
ENSDARG00000108220
chr7_-_15008685 1.43 ENSDART00000173048
ENSDARG00000023868
ENSDARG00000023868
chr1_-_6989681 1.42 ENSDART00000013264
arglu1b
arginine and glutamate rich 1b
chr15_+_20303539 1.42 ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr7_-_22361507 1.41 ENSDART00000165245
si:dkey-112a7.4
si:dkey-112a7.4
chr17_+_25314229 1.40 ENSDART00000082319
tmem54a
transmembrane protein 54a
chr8_-_37989930 1.40

chr15_+_44168674 1.39

chr4_-_72771281 1.38 ENSDART00000164550
ENSDART00000174320
RAB21
RAB21, member RAS oncogene family
chr19_-_6401104 1.38

chr5_+_424789 1.38 ENSDART00000170350
thap1
THAP domain containing, apoptosis associated protein 1
chr3_-_25142093 1.35

chr15_+_20303330 1.35 ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
chr18_-_26799173 1.34 ENSDART00000136776
ENSDART00000076484
kti12
KTI12 chromatin associated homolog
chr15_-_19192862 1.32 ENSDART00000152428
arhgap32a
Rho GTPase activating protein 32a
chr23_+_6610707 1.31 ENSDART00000005373
spo11
SPO11 meiotic protein covalently bound to DSB
chr2_-_56632969 1.31 ENSDART00000089158
hmha1a
histocompatibility (minor) HA-1 a
chr4_+_10693633 1.31

chr5_-_16294335 1.30

chr22_+_23260413 1.28

chr15_-_43283562 1.27 ENSDART00000110352
ap1s3a
adaptor-related protein complex 1, sigma 3 subunit, a
chr24_-_42045374 1.27

chr16_+_33209956 1.26 ENSDART00000101943
rragca
Ras-related GTP binding Ca
chr20_-_3220522 1.25 ENSDART00000008077
spint1b
serine peptidase inhibitor, Kunitz type 1 b
chr7_+_20651775 1.25 ENSDART00000129161
wrap53
WD repeat containing, antisense to TP53
chr21_-_43671213 1.25 ENSDART00000139008
si:dkey-229d11.3
si:dkey-229d11.3
chr25_+_30627755 1.24

chr13_-_44882023 1.24

chr6_-_10492724 1.24 ENSDART00000002247
sp3b
Sp3b transcription factor
chr15_-_19192933 1.23 ENSDART00000152428
arhgap32a
Rho GTPase activating protein 32a
chr10_+_4924065 1.21 ENSDART00000108595
slc46a2
solute carrier family 46 member 2
chr5_-_11530803 1.21 ENSDART00000159896
gatsl3
GATS protein-like 3
chr5_-_16294285 1.21

chr20_+_27341244 1.20 ENSDART00000123950
ENSDARG00000077377
ENSDARG00000077377
chr15_+_12127861 1.19

chr7_+_67475893 1.19 ENSDART00000160086
zgc:162592
zgc:162592
chr10_+_6338988 1.17 ENSDART00000160813
tpm2
tropomyosin 2 (beta)
chr4_-_12979951 1.17 ENSDART00000013839
tmbim4
transmembrane BAX inhibitor motif containing 4
chr20_-_42095478 1.16 ENSDART00000100967
si:dkeyp-114g9.1
si:dkeyp-114g9.1
chr20_-_23354440 1.16 ENSDART00000103365
ociad1
OCIA domain containing 1
chr17_-_25865861 1.16

chr12_-_30244042 1.16 ENSDART00000152878
tdrd1
tudor domain containing 1
chr10_+_43953171 1.15

chr12_-_30244575 1.14 ENSDART00000152981
tdrd1
tudor domain containing 1
chr15_+_20303673 1.14 ENSDART00000152473
spint2
serine peptidase inhibitor, Kunitz type, 2
KN150455v1_-_14097 1.12

chr5_+_22470117 1.10 ENSDART00000020434
brwd3
bromodomain and WD repeat domain containing 3
chr20_-_25731057 1.09

chr9_-_25151812 1.09

chr15_+_1238560 1.09 ENSDART00000167760
ENSDART00000163827
mfsd1
major facilitator superfamily domain containing 1
chr7_-_54170414 1.08

chr10_-_2944295 1.07 ENSDART00000132526
marveld2a
MARVEL domain containing 2a
chr24_-_9153609 1.07 ENSDART00000082434
tgif1
TGFB-induced factor homeobox 1
chr7_-_19116856 1.06 ENSDART00000165680
ntn4
netrin 4
chr20_+_32853879 1.06 ENSDART00000023006
fam84a
family with sequence similarity 84, member A
chr25_-_22791921 1.05 ENSDART00000128250
mob2a
MOB kinase activator 2a
chr7_+_5853590 1.05 ENSDART00000123660
HIST2H2AB (1 of many)
histone cluster 2 H2A family member b
chr12_+_30590876 1.02 ENSDART00000066259
kcnk1a
potassium channel, subfamily K, member 1a
chr5_-_36348618 1.02

chr5_+_58006479 1.02

chr1_-_48876873 1.00 ENSDART00000143474
zp3c
zona pellucida glycoprotein 3c
chr18_+_12157410 1.00

chr7_+_50126951 0.99 ENSDART00000028105
mfap1
microfibrillar-associated protein 1
chr5_+_41658782 0.98 ENSDART00000143738
eral1
Era-like 12S mitochondrial rRNA chaperone 1
chr19_-_15324823 0.98 ENSDART00000169883
phactr4a
phosphatase and actin regulator 4a
chr21_-_35291005 0.98 ENSDART00000134780
ublcp1
ubiquitin-like domain containing CTD phosphatase 1
chr25_-_31547164 0.97 ENSDART00000110180
duox2
dual oxidase 2
chr14_+_29945396 0.96 ENSDART00000173090
mtus1a
microtubule associated tumor suppressor 1a
chr18_+_12157372 0.95

chr24_-_9153466 0.95 ENSDART00000082434
tgif1
TGFB-induced factor homeobox 1
chr7_+_73583860 0.94 ENSDART00000166244
si:ch73-252p3.1
si:ch73-252p3.1
chr9_+_18565169 0.94

chr3_-_32231192 0.93 ENSDART00000012630
prmt1
protein arginine methyltransferase 1
chr7_-_15008648 0.93 ENSDART00000173048
ENSDARG00000023868
ENSDARG00000023868
chr20_+_29663726 0.92

chr1_-_6989486 0.90 ENSDART00000013264
arglu1b
arginine and glutamate rich 1b
chr1_+_28936288 0.90

KN150200v1_+_7856 0.90

chr2_+_26581725 0.90 ENSDART00000030520
palm1b
paralemmin 1b
chr15_-_34810397 0.90

chr16_-_29470491 0.89 ENSDART00000175571
tlr18
toll-like receptor 18
chr18_-_14910358 0.88 ENSDART00000099701
selo
selenoprotein O
chr12_-_292556 0.88 ENSDART00000152608
CU611036.1
ENSDARG00000079888
chr1_+_40428827 0.86 ENSDART00000145272
lrpap1
low density lipoprotein receptor-related protein associated protein 1
chr25_-_22791839 0.86 ENSDART00000128250
mob2a
MOB kinase activator 2a
chr16_+_41110027 0.86 ENSDART00000141130
scap
SREBF chaperone
chr1_-_48876896 0.86 ENSDART00000143474
zp3c
zona pellucida glycoprotein 3c
chr15_+_38319554 0.86 ENSDART00000122134
stim1a
stromal interaction molecule 1a
chr13_-_24538905 0.86 ENSDART00000000831
znf511
zinc finger protein 511
chr3_-_31942015 0.85

chr12_-_36113358 0.84

chr16_-_17807118 0.84 ENSDART00000149275
zgc:174935
zgc:174935
chr17_-_6377533 0.84 ENSDART00000156903
cenpo
centromere protein O
chr5_-_66571831 0.84 ENSDART00000114783
clip1a
CAP-GLY domain containing linker protein 1a
chr8_+_2398268 0.83 ENSDART00000133938
ENSDART00000002764
polb
polymerase (DNA directed), beta
chr4_-_10836696 0.83 ENSDART00000150739
ppfibp1a
PTPRF interacting protein, binding protein 1a (liprin beta 1)
chr22_-_26231695 0.80 ENSDART00000142821
ccdc130
coiled-coil domain containing 130
chr22_+_23260052 0.80

chr15_-_16241500 0.80 ENSDART00000156352
si:ch211-259g3.4
si:ch211-259g3.4
chr19_-_15324909 0.80 ENSDART00000169883
phactr4a
phosphatase and actin regulator 4a
chr17_-_38939665 0.79 ENSDART00000141177
slc24a4a
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4a
chr5_+_50266345 0.78 ENSDART00000092938
col4a3bpa
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr21_-_16442202 0.78

chr3_-_59736167 0.78 ENSDART00000154684
recql5
RecQ helicase-like 5
chr10_-_4924455 0.78

chr16_-_32622630 0.77

chr25_+_27300835 0.77 ENSDART00000103519
wasla
Wiskott-Aldrich syndrome-like a
chr11_-_25615683 0.77 ENSDART00000145655
tmem51b
transmembrane protein 51b
chr6_-_12268874 0.76

chr14_-_30747259 0.76 ENSDART00000002250
hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr18_+_22299937 0.76

chr4_-_16611908 0.76

chr13_-_24538832 0.76 ENSDART00000000831
znf511
zinc finger protein 511
chr10_+_44847446 0.76

chr19_-_307085 0.76 ENSDART00000145916
lingo4a
leucine rich repeat and Ig domain containing 4a
chr21_+_30757998 0.75 ENSDART00000139486
ENSDARG00000030006
ENSDARG00000030006
chr5_+_22470177 0.75 ENSDART00000020434
brwd3
bromodomain and WD repeat domain containing 3
chr22_+_22413878 0.74 ENSDART00000147825
kif14
kinesin family member 14

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 15.4 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
1.1 3.3 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.9 2.7 GO:0046081 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.9 3.6 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.8 3.1 GO:0022602 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.6 10.6 GO:0035803 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.5 2.9 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.4 2.1 GO:0003379 establishment of cell polarity involved in gastrulation cell migration(GO:0003379)
0.4 1.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.3 1.7 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.3 2.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.2 2.9 GO:0070831 basement membrane assembly(GO:0070831)
0.2 0.9 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.2 2.3 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.2 0.9 GO:0010915 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) regulation of lipoprotein particle clearance(GO:0010984) negative regulation of lipoprotein particle clearance(GO:0010985)
0.2 1.9 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.2 1.6 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.2 0.8 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.2 1.5 GO:0006012 galactose metabolic process(GO:0006012)
0.1 0.7 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.8 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.1 1.2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 3.5 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 2.1 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 0.7 GO:0030262 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 0.6 GO:0090199 regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 2.0 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.1 0.7 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 5.9 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.7 GO:0060829 negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060829)
0.1 1.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.8 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 1.4 GO:0035778 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.1 1.5 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.1 4.3 GO:0001706 endoderm formation(GO:0001706)
0.1 0.9 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 4.2 GO:0097191 extrinsic apoptotic signaling pathway(GO:0097191)
0.1 1.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.6 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.1 1.6 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 1.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.6 GO:0001878 response to yeast(GO:0001878)
0.0 0.6 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 4.8 GO:0006936 muscle contraction(GO:0006936)
0.0 0.5 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.3 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.8 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 2.4 GO:0009617 response to bacterium(GO:0009617)
0.0 2.4 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 2.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 2.9 GO:0017148 negative regulation of translation(GO:0017148)
0.0 0.7 GO:0006278 RNA-dependent DNA biosynthetic process(GO:0006278) telomere maintenance via telomerase(GO:0007004)
0.0 0.6 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 2.0 GO:0045055 regulated exocytosis(GO:0045055)
0.0 1.4 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 2.4 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.9 GO:0000819 sister chromatid segregation(GO:0000819)
0.0 0.1 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.0 0.3 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 1.7 GO:0034976 response to endoplasmic reticulum stress(GO:0034976)
0.0 0.4 GO:0009395 phospholipid catabolic process(GO:0009395)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.4 2.6 GO:0001650 fibrillar center(GO:0001650)
0.4 1.1 GO:0061689 tricellular tight junction(GO:0061689)
0.3 2.3 GO:0071546 pi-body(GO:0071546)
0.3 2.9 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 1.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 1.6 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 0.7 GO:0070209 ASTRA complex(GO:0070209)
0.2 1.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2 1.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 0.8 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.2 2.9 GO:0015030 Cajal body(GO:0015030)
0.1 4.8 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 2.1 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 2.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.1 GO:0030057 desmosome(GO:0030057)
0.1 2.4 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 1.3 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 2.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.8 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.5 GO:0008278 cohesin complex(GO:0008278)
0.0 1.0 GO:0043204 perikaryon(GO:0043204)
0.0 4.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 3.3 GO:0000228 nuclear chromosome(GO:0000228)
0.0 1.0 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 0.6 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 3.2 GO:0000785 chromatin(GO:0000785)
0.0 0.2 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.1 GO:0031012 extracellular matrix(GO:0031012)
0.0 9.3 GO:0005794 Golgi apparatus(GO:0005794)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.7 2.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.6 10.6 GO:0032190 acrosin binding(GO:0032190)
0.6 1.8 GO:0016843 amine-lyase activity(GO:0016843) strictosidine synthase activity(GO:0016844)
0.6 2.3 GO:0034584 piRNA binding(GO:0034584)
0.6 2.2 GO:1903231 mRNA binding involved in posttranscriptional gene silencing(GO:1903231)
0.5 3.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.4 3.3 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.4 1.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.3 1.2 GO:0004937 alpha-adrenergic receptor activity(GO:0004936) alpha1-adrenergic receptor activity(GO:0004937)
0.3 1.5 GO:0004335 galactokinase activity(GO:0004335)
0.2 15.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 2.1 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 1.6 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 0.6 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity(GO:0047464)
0.2 0.7 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.2 4.2 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.2 0.9 GO:0048019 receptor antagonist activity(GO:0048019)
0.2 0.8 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 5.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.8 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 3.5 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.0 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 1.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.1 0.8 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 1.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 3.2 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.3 GO:0046592 polyamine oxidase activity(GO:0046592)
0.1 0.9 GO:0016273 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 5.2 GO:0003724 RNA helicase activity(GO:0003724)
0.1 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 2.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 1.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 1.9 GO:0008373 sialyltransferase activity(GO:0008373)
0.1 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 2.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.8 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.5 GO:0032934 sterol binding(GO:0032934)
0.0 2.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 5.0 GO:0008017 microtubule binding(GO:0008017)
0.0 7.7 GO:0051015 actin filament binding(GO:0051015)
0.0 2.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 2.4 GO:0060090 binding, bridging(GO:0060090)
0.0 0.6 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 2.6 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.3 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 1.4 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 2.1 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 1.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 5.6 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.6 PID IGF1 PATHWAY IGF1 pathway
0.0 2.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.1 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.3 4.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 1.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 2.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 2.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 0.8 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 2.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 2.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 1.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 3.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.8 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME EARLY PHASE OF HIV LIFE CYCLE Genes involved in Early Phase of HIV Life Cycle