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Results for smad3a+smad3b

Z-value: 0.78

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Transcription factors associated with smad3a+smad3b

Gene Symbol Gene ID Gene Info
smad3b
ENSDARG00000010207 SMAD family member 3b
smad3a
ENSDARG00000036096 SMAD family member 3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
smad3adr10_dc_chr7_-_33878076_338781470.401.3e-01Click!
smad3bdr10_dc_chr18_+_19783732_197837880.381.5e-01Click!

Activity profile of smad3a+smad3b motif

Sorted Z-values of smad3a+smad3b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of smad3a+smad3b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr5_+_23802054 2.14 ENSDART00000144226
ctsll
cathepsin L, like
chr2_-_20941256 1.88 ENSDART00000114199
si:ch211-267e7.3
si:ch211-267e7.3
chr2_-_59047356 1.67

chr19_-_3226831 1.67 ENSDART00000145710
ENSDART00000110763
ENSDART00000074620
stm
starmaker
chr21_+_26035166 1.38 ENSDART00000134939
rpl23a
ribosomal protein L23a
chr8_-_13503775 1.36 ENSDART00000063834
ENSDARG00000043482
ENSDARG00000043482
chr12_-_17357133 1.30 ENSDART00000079115
papss2b
3'-phosphoadenosine 5'-phosphosulfate synthase 2b
chr3_-_44113070 1.25 ENSDART00000160717
znf750
zinc finger protein 750
chr1_+_46487300 1.18 ENSDART00000158432
ENSDART00000074450
morc3b
MORC family CW-type zinc finger 3b
chr24_-_33377293 1.13 ENSDART00000124938
si:ch1073-406l10.2
si:ch1073-406l10.2
chr14_+_38445969 1.11 ENSDART00000164440
si:ch211-195b11.3
si:ch211-195b11.3
chr6_-_40774050 1.10 ENSDART00000076200
h1fx
H1 histone family, member X
chr14_+_27936303 1.06 ENSDART00000003293
mid2
midline 2
chr6_-_39311711 1.06

chr9_+_3147601 1.06 ENSDART00000135619
ftr52p
finTRIM family, member 52, pseudogene
chr10_+_26020615 1.05 ENSDART00000128292
ENSDART00000170275
ENSDART00000166164
ENSDART00000108808
frem2a
Fras1 related extracellular matrix protein 2a
chr25_+_35796086 1.04 ENSDART00000112196
HIST2H4B
zgc:163040
chr3_+_48362748 1.04 ENSDART00000157199
mkl2b
MKL/myocardin-like 2b
chr8_-_38168395 1.03 ENSDART00000155189
pdlim2
PDZ and LIM domain 2 (mystique)
chr23_-_9556986 1.01 ENSDART00000139688
soga1
suppressor of glucose, autophagy associated 1
chr4_+_29842350 0.99

chr22_-_28922834 0.97 ENSDART00000104828
gtpbp2b
GTP binding protein 2b
chr25_+_35765309 0.94 ENSDART00000128547
hist1h4l
histone 1, H4, like
chr6_+_6333766 0.89 ENSDART00000140827
bcl11ab
B-cell CLL/lymphoma 11Ab
chr8_+_1122000 0.87 ENSDART00000127252
slc35d2
solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr4_-_72067910 0.87 ENSDART00000170308
BX855614.3
ENSDARG00000101193
chr6_-_50705420 0.83 ENSDART00000074100
osgn1
oxidative stress induced growth inhibitor 1
chr23_-_46250905 0.83 ENSDART00000160110
tgm1l4
transglutaminase 1 like 4
chr19_-_9043897 0.82 ENSDART00000104657
mrps21
mitochondrial ribosomal protein S21
chr23_-_24755654 0.80 ENSDART00000104035
ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr7_-_69639922 0.79

chr11_-_23079615 0.75 ENSDART00000125024
golt1a
golgi transport 1A
chr23_+_2597825 0.73 ENSDART00000159039
ENSDARG00000089986
ENSDARG00000089986
KN149816v1_-_3337 0.72

chr20_-_53271601 0.72

KN150670v1_-_72156 0.68

chr25_+_34560773 0.68 ENSDART00000157248
ENSDARG00000097103
ENSDARG00000097103
chr21_-_26035057 0.66 ENSDART00000141382
rab34b
RAB34, member RAS oncogene family b
chr14_-_27754549 0.63 ENSDART00000135337
zgc:64189
zgc:64189
chr12_-_3741925 0.62 ENSDART00000092983
ENSDARG00000063555
ENSDARG00000063555
chr8_-_37011436 0.62 ENSDART00000139567
renbp
renin binding protein
chr7_-_57941497 0.61 ENSDART00000114008
unm_hu7910
un-named hu7910
chr4_-_14330113 0.58 ENSDART00000091151
nell2b
neural EGFL like 2b
chr14_+_6239755 0.57 ENSDART00000097214
adam19b
ADAM metallopeptidase domain 19b
chr4_-_74907755 0.55 ENSDART00000132323
ftr51
finTRIM family, member 51
chr13_+_1314139 0.55

chr15_-_41777233 0.54 ENSDART00000154230
ftr90
finTRIM family, member 90
chr18_-_36956268 0.54

chr8_+_8673307 0.54 ENSDART00000110854
elk1
ELK1, member of ETS oncogene family
chr2_+_54911012 0.53 ENSDART00000027313
ndufv2
NADH dehydrogenase (ubiquinone) flavoprotein 2
chr10_+_29351676 0.52 ENSDART00000088973
sytl2a
synaptotagmin-like 2a
chr3_-_28741820 0.52 ENSDART00000138840
eef2kmt
eukaryotic elongation factor 2 lysine methyltransferase
chr2_-_37914464 0.51 ENSDART00000129852
hbl1
hexose-binding lectin 1
chr7_-_6273677 0.50 ENSDART00000173419
si:ch73-368j24.1
si:ch73-368j24.1
chr2_-_59293269 0.49 ENSDART00000148286
ftr39p
finTRIM family, member 39, pseudogene
chr25_+_34551602 0.49 ENSDART00000121825
hist1h4l
histone 1, H4, like
chr11_-_14943957 0.49 ENSDART00000162938
hug
HuG
chr20_+_46309812 0.47 ENSDART00000100532
stx7l
syntaxin 7-like
chr6_+_58704352 0.46 ENSDART00000172466
igsf8
immunoglobulin superfamily, member 8
chr2_-_20941390 0.46 ENSDART00000114199
si:ch211-267e7.3
si:ch211-267e7.3
chr5_-_57016269 0.45 ENSDART00000074264
crfb12
cytokine receptor family member B12
chr3_-_40385307 0.43

chr25_-_34642724 0.43 ENSDART00000121963
hist1h4l
histone 1, H4, like
chr9_-_16845777 0.43 ENSDART00000160273
ENSDARG00000102261
ENSDARG00000102261
chr23_-_46251021 0.43 ENSDART00000160110
tgm1l4
transglutaminase 1 like 4
chr14_+_8198019 0.42 ENSDART00000123364
vegfba
vascular endothelial growth factor Ba
KN150423v1_-_9765 0.42

chr1_+_53384116 0.42 ENSDART00000149760
triobpa
TRIO and F-actin binding protein a
chr19_+_628049 0.41 ENSDART00000098884
ENSDART00000170433
tert
telomerase reverse transcriptase
chr20_+_19662825 0.41 ENSDART00000103798
nme6
NME/NM23 nucleoside diphosphate kinase 6
chr5_+_35198499 0.40

chr17_-_45403518 0.38 ENSDART00000156002
tmem206
transmembrane protein 206
chr2_+_23038657 0.38 ENSDART00000089012
kif1ab
kinesin family member 1Ab
chr17_+_14878846 0.37 ENSDART00000010507
ENSDART00000131052
ptger2a
prostaglandin E receptor 2a (subtype EP2)
chr23_+_25381458 0.37 ENSDART00000140463
esyt1a
extended synaptotagmin-like protein 1a
chr7_-_24119645 0.36 ENSDART00000141769
ptgr1
prostaglandin reductase 1
chr1_+_44414936 0.36

chr7_+_21455482 0.35

chr7_+_5837533 0.35 ENSDART00000110813
hist1h4l
histone 1, H4, like
chr25_-_22242337 0.35

chr5_+_1164747 0.35 ENSDART00000129490
gb:bc139872
expressed sequence BC139872
chr15_+_46129807 0.33 ENSDART00000153936
si:ch1073-340i21.2
si:ch1073-340i21.2
chr21_-_17566461 0.32 ENSDART00000044078
ENSDART00000168495
ENSDART00000020048
gsna
gelsolin a
chr17_-_27254921 0.31 ENSDART00000077087
id3
inhibitor of DNA binding 3
chr1_-_22170553 0.31 ENSDART00000139412
SMIM18
small integral membrane protein 18
chr10_-_22881453 0.31

chr1_+_46487378 0.31 ENSDART00000137448
morc3b
MORC family CW-type zinc finger 3b
chr13_+_19115 0.30 ENSDART00000176574
CABZ01089797.1
ENSDARG00000107538
chr20_+_46969915 0.30 ENSDART00000158124
ENSDARG00000103380
ENSDARG00000103380
chr1_+_23093475 0.30

chr4_-_75690772 0.30 ENSDART00000174183
CABZ01063884.1
ENSDARG00000105697
chr5_+_30725475 0.30

chr4_-_14330048 0.29 ENSDART00000091151
nell2b
neural EGFL like 2b
chr5_+_20340093 0.29 ENSDART00000139260
limk2
LIM domain kinase 2
chr7_+_73603232 0.29 ENSDART00000112685
hist1h4l
histone 1, H4, like
chr20_-_53271658 0.29

chr9_+_24089828 0.28 ENSDART00000127859
trim63b
tripartite motif containing 63b
chr17_+_44666606 0.28 ENSDART00000155096
tmem63c
transmembrane protein 63C
chr14_+_20614087 0.28 ENSDART00000160318
lygl2
lysozyme g-like 2
chr18_+_17622557 0.27 ENSDART00000046891
cetp
cholesteryl ester transfer protein, plasma
chr24_+_4402474 0.27 ENSDART00000066836
GJD4
gap junction protein delta 4
chr12_-_16514995 0.26 ENSDART00000128811
si:dkey-239j18.3
si:dkey-239j18.3
chr20_+_4840692 0.26

chr13_+_36638875 0.26 ENSDART00000111832
atl1
atlastin GTPase 1
chr25_-_20170375 0.25 ENSDART00000138763
dnajb9a
DnaJ (Hsp40) homolog, subfamily B, member 9a
chr23_+_35954132 0.25 ENSDART00000103149
hoxc13a
homeobox C13a
chr15_+_9096765 0.24 ENSDART00000080196
si:dkey-202g17.3
si:dkey-202g17.3
chr16_-_2570425 0.24

chr3_+_31793328 0.24 ENSDART00000127330
ENSDART00000126773
ENSDART00000055279
snrnp70
small nuclear ribonucleoprotein 70 (U1)
chr1_-_29562875 0.24 ENSDART00000125759
si:dkey-22o12.2
si:dkey-22o12.2
chr17_-_53266905 0.24

chr21_+_25496520 0.24 ENSDART00000134052
si:dkey-17e16.8
si:dkey-17e16.8
chr14_-_6822151 0.23 ENSDART00000171311
si:ch73-43g23.1
si:ch73-43g23.1
chr3_+_24059652 0.23 ENSDART00000034762
prr15la
proline rich 15-like a
chr8_-_18167468 0.23 ENSDART00000137005
elovl8b
ELOVL fatty acid elongase 8b
chr24_-_25189173 0.22

chr19_-_6963103 0.21

chr10_+_17634410 0.21 ENSDART00000168635
KCNN2
potassium calcium-activated channel subfamily N member 2
chr25_+_17906515 0.20

chr8_+_23172960 0.20 ENSDART00000028946
tpd52l2a
tumor protein D52-like 2a
chr8_+_39726489 0.19 ENSDART00000037914
cox6a1
cytochrome c oxidase subunit VIa polypeptide 1
chr21_+_25496914 0.19 ENSDART00000134052
si:dkey-17e16.8
si:dkey-17e16.8
chr25_-_35451402 0.19 ENSDART00000066987
mphosph6
M-phase phosphoprotein 6
chr8_-_18167570 0.19 ENSDART00000142114
elovl8b
ELOVL fatty acid elongase 8b
chr25_+_30838768 0.17

chr20_-_54364559 0.17

chr16_-_48189682 0.17

chr24_+_42193701 0.16 ENSDART00000067734
snx16
sorting nexin 16
KN150423v1_-_9882 0.16

chr25_-_17906739 0.16 ENSDART00000149696
cep290
centrosomal protein 290
chr17_-_44895892 0.16 ENSDART00000123971
fam161b
family with sequence similarity 161, member B
chr23_+_14172256 0.15 ENSDART00000155326
si:dkey-90a13.10
si:dkey-90a13.10
chr5_-_31116505 0.15 ENSDART00000131443
dpm2
dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
chr3_-_4590689 0.14 ENSDART00000163052
ENSDART00000164569
ENSDARG00000098540
ENSDARG00000098540
chr19_+_48166365 0.14

chr25_+_17906724 0.14

chr24_-_41917835 0.14

chr3_+_36497377 0.13

chr10_+_21760897 0.12 ENSDART00000176794
pcdh1gb9
protocadherin 1 gamma b 9
chr7_+_59494488 0.12

chr22_+_1509147 0.12 ENSDART00000164089
si:ch211-255f4.6
si:ch211-255f4.6
chr2_+_35505943 0.10 ENSDART00000131248
CR855337.1
ENSDARG00000094295
chr18_+_17564926 0.10

chr19_+_9868101 0.09 ENSDART00000138310
cacng6a
calcium channel, voltage-dependent, gamma subunit 6a
chr24_-_42193714 0.09

chr3_-_32457740 0.09

chr23_+_25005457 0.09 ENSDART00000136162
klhl21
kelch-like family member 21
chr6_+_19476202 0.09 ENSDART00000113911
micall1a
MICAL-like 1a
chr5_-_1164454 0.08 ENSDART00000054070
surf2
surfeit 2
chr3_-_40385511 0.08

chr8_-_3287944 0.06 ENSDART00000057874
FUT9 (1 of many)
fucosyltransferase 9
chr5_-_336852 0.06

chr5_+_62696901 0.06 ENSDART00000124616
rab14
RAB14, member RAS oncogene family
chr17_+_44896297 0.06 ENSDART00000133103
coq6
coenzyme Q6 monooxygenase
chr12_-_46943791 0.05 ENSDART00000084557
lhpp
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr7_-_51210658 0.05 ENSDART00000174026
nhsl2
NHS-like 2
chr25_+_35451459 0.05

chr25_+_19889409 0.05 ENSDART00000178266
ENSDART00000121226
FO704882.1
ENSDARG00000085826
chr9_-_23107452 0.05 ENSDART00000007392
arl5a
ADP-ribosylation factor-like 5A
chr24_-_25189252 0.05

chr12_-_18438618 0.03 ENSDART00000078172
bricd5
BRICHOS domain containing 5
chr16_-_24646282 0.03 ENSDART00000126274
si:ch211-79k12.2
si:ch211-79k12.2
chr7_-_2230502 0.03 ENSDART00000173879
si:cabz01007794.1
si:cabz01007794.1
chr17_-_53266811 0.02

chr25_+_35451721 0.01

chr18_-_20570874 0.01 ENSDART00000141367
si:ch211-238n5.4
si:ch211-238n5.4
chr16_-_32250329 0.00 ENSDART00000143928
rwdd1
RWD domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0045299 otolith mineralization(GO:0045299)
0.2 1.3 GO:0050427 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 0.6 GO:0042264 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.2 0.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.1 1.3 GO:0018149 peptide cross-linking(GO:0018149)
0.1 1.1 GO:0050994 regulation of lipid catabolic process(GO:0050994)
0.1 0.3 GO:0071554 cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.1 0.3 GO:0055091 triglyceride-rich lipoprotein particle remodeling(GO:0034370) very-low-density lipoprotein particle remodeling(GO:0034372) reverse cholesterol transport(GO:0043691) phospholipid homeostasis(GO:0055091)
0.1 0.4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 1.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.4 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.4 GO:0060753 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.1 0.6 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.4 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 1.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.9 GO:0050773 regulation of dendrite development(GO:0050773)
0.0 0.1 GO:1902514 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 2.5 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.2 GO:0007622 rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:0098927 protein targeting to lysosome(GO:0006622) early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 1.1 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.3 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 1.1 GO:0033334 fin morphogenesis(GO:0033334)
0.0 2.3 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.4 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0001845 phagolysosome assembly(GO:0001845)
0.0 0.3 GO:0051014 actin filament severing(GO:0051014)
0.0 0.4 GO:0007596 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.0 1.3 GO:0008544 epidermis development(GO:0008544)
0.0 1.0 GO:0010506 regulation of autophagy(GO:0010506)
0.0 0.3 GO:0003094 glomerular filtration(GO:0003094)
0.0 2.4 GO:0006955 immune response(GO:0006955)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.0 0.2 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.0 GO:0031941 filamentous actin(GO:0031941)
0.0 3.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.3 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0005685 U1 snRNP(GO:0005685)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0005461 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.2 1.3 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 1.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.4 GO:0004953 icosanoid receptor activity(GO:0004953)
0.1 0.4 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.1 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.1 0.9 GO:0005080 protein kinase C binding(GO:0005080)
0.1 0.8 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 1.0 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.4 GO:0019843 rRNA binding(GO:0019843)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0030619 U1 snRNA binding(GO:0030619)
0.0 0.3 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.1 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 3.0 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.4 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.6 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.4 GO:0004896 cytokine receptor activity(GO:0004896)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance