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Results for snai1b+snai3

Z-value: 0.81

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Transcription factors associated with snai1b+snai3

Gene Symbol Gene ID Gene Info
snai3
ENSDARG00000031243 snail family zinc finger 3
snai1b
ENSDARG00000046019 snail family zinc finger 1b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
snai1bdr10_dc_chr23_-_2573949_2573956-0.611.2e-02Click!
snai3dr10_dc_chr7_+_54811485_548114990.542.9e-02Click!

Activity profile of snai1b+snai3 motif

Sorted Z-values of snai1b+snai3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of snai1b+snai3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_+_58448953 3.60 ENSDART00000024185
zgc:56231
zgc:56231
chr1_+_41762057 3.25 ENSDART00000137609
ctnna2
catenin (cadherin-associated protein), alpha 2
chr7_-_55346967 2.70 ENSDART00000135304
pabpn1l
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr22_+_25113293 2.08 ENSDART00000171851
si:ch211-226h8.4
si:ch211-226h8.4
chr9_-_28444272 1.79 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr13_-_21541531 1.77 ENSDART00000067537
elovl6l
ELOVL family member 6, elongation of long chain fatty acids like
chr12_+_22551105 1.69 ENSDART00000123808
ENSDART00000159864
cdca9
cell division cycle associated 9
chr20_-_23527234 1.66 ENSDART00000004625
zar1
zygote arrest 1
chr7_+_58449163 1.66 ENSDART00000167166
zgc:56231
zgc:56231
chr19_+_33552393 1.57 ENSDART00000043039
fam84b
family with sequence similarity 84, member B
chr10_+_37229202 1.53 ENSDART00000136510
ksr1a
kinase suppressor of ras 1a
chr12_-_2834771 1.52 ENSDART00000114854
ENSDART00000163759
zdhhc16b
zinc finger, DHHC-type containing 16b
chr9_-_28444024 1.46 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr5_-_11530803 1.42 ENSDART00000159896
gatsl3
GATS protein-like 3
chr7_+_58449127 1.40 ENSDART00000167166
zgc:56231
zgc:56231
chr22_+_22413803 1.36 ENSDART00000147825
kif14
kinesin family member 14
chr20_-_43846604 1.17 ENSDART00000150078
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr5_-_23192997 1.09 ENSDART00000167629
rnf128a
ring finger protein 128a
chr12_-_35467285 1.03 ENSDART00000160336
sec24c
SEC24 homolog C, COPII coat complex component
chr22_-_26231695 0.93 ENSDART00000142821
ccdc130
coiled-coil domain containing 130
chr9_-_28443972 0.93 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr22_+_2237813 0.90

chr5_-_23192934 0.87 ENSDART00000021462
rnf128a
ring finger protein 128a
chr7_+_58448909 0.85 ENSDART00000024185
zgc:56231
zgc:56231
chr8_-_10912137 0.76 ENSDART00000064058
ENSDART00000162109
ENSDART00000101277
pqlc2
PQ loop repeat containing 2
chr20_-_43846553 0.75 ENSDART00000150078
si:dkeyp-50f7.2
si:dkeyp-50f7.2
chr19_-_32314264 0.72

chr25_+_27301039 0.70 ENSDART00000149456
wasla
Wiskott-Aldrich syndrome-like a
chr6_-_10492724 0.68 ENSDART00000002247
sp3b
Sp3b transcription factor
chr16_-_29470491 0.67 ENSDART00000175571
tlr18
toll-like receptor 18
chr12_+_16831493 0.64 ENSDART00000020824
pank1b
pantothenate kinase 1b
chr23_+_34120843 0.63 ENSDART00000143339
chchd6a
coiled-coil-helix-coiled-coil-helix domain containing 6a
chr22_+_22413878 0.62 ENSDART00000147825
kif14
kinesin family member 14
chr2_-_56632969 0.61 ENSDART00000089158
hmha1a
histocompatibility (minor) HA-1 a
chr21_-_35291005 0.61 ENSDART00000134780
ublcp1
ubiquitin-like domain containing CTD phosphatase 1
chr15_+_1238560 0.60 ENSDART00000167760
ENSDART00000163827
mfsd1
major facilitator superfamily domain containing 1
chr15_+_12127861 0.58

chr9_-_28444210 0.58 ENSDART00000160387
ccnyl1
cyclin Y-like 1
chr1_+_40134375 0.57 ENSDART00000177517
CR387992.1
ENSDARG00000108790
chr7_+_73583860 0.57 ENSDART00000166244
si:ch73-252p3.1
si:ch73-252p3.1
chr6_-_37771729 0.56 ENSDART00000078324
nipa1
non imprinted in Prader-Willi/Angelman syndrome 1
chr16_+_41110027 0.55 ENSDART00000141130
scap
SREBF chaperone
chr7_+_67475893 0.55 ENSDART00000160086
zgc:162592
zgc:162592
chr14_-_30747372 0.55 ENSDART00000002250
hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr1_-_529071 0.55 ENSDART00000147610
si:ch73-41e3.7
si:ch73-41e3.7
chr23_+_34121048 0.50 ENSDART00000143339
chchd6a
coiled-coil-helix-coiled-coil-helix domain containing 6a
chr22_-_26231606 0.49 ENSDART00000060888
ccdc130
coiled-coil domain containing 130
chr17_+_24571678 0.46 ENSDART00000092941
rlf
rearranged L-myc fusion
chr7_+_20829933 0.41 ENSDART00000173612
serpinh2
serine (or cysteine) peptidase inhibitor, clade H, member 2
chr5_-_68712851 0.41 ENSDART00000109487
CABZ01032476.1
ENSDARG00000074645
chr20_-_25731057 0.36

KN150232v1_+_13079 0.36 ENSDART00000174701
CABZ01084889.1
ENSDARG00000107269
chr3_+_14492079 0.34 ENSDART00000091070
zgc:158403
zgc:158403
chr11_+_6893104 0.33 ENSDART00000144006
crtc1b
CREB regulated transcription coactivator 1b
chr8_-_17736169 0.33 ENSDART00000063592
ENSDART00000175064
prkcz
protein kinase C, zeta
chr25_+_27300835 0.33 ENSDART00000103519
wasla
Wiskott-Aldrich syndrome-like a
chr24_-_41160119 0.31 ENSDART00000173529
ENSDART00000159738
ttc21a
tetratricopeptide repeat domain 21A
chr5_-_21548930 0.30 ENSDART00000002938
mtmr8
myotubularin related protein 8
chr6_-_21756764 0.28 ENSDART00000167937
p4hb
prolyl 4-hydroxylase, beta polypeptide
chr13_-_21541412 0.25 ENSDART00000067537
elovl6l
ELOVL family member 6, elongation of long chain fatty acids like
chr25_+_5232982 0.24

chr14_-_14849759 0.22 ENSDART00000172666
uvssa
UV-stimulated scaffold protein A
chr2_-_56632913 0.22 ENSDART00000089158
hmha1a
histocompatibility (minor) HA-1 a
chr7_-_30654776 0.20 ENSDART00000075421
sord
sorbitol dehydrogenase
chr13_-_36400356 0.19 ENSDART00000175311
pacs2
phosphofurin acidic cluster sorting protein 2
chr5_-_11530880 0.18 ENSDART00000159896
gatsl3
GATS protein-like 3
chr22_-_26504565 0.18 ENSDART00000087623
zgc:194330
zgc:194330
chr17_-_25865861 0.17

chr16_-_9939497 0.16 ENSDART00000148528
grhl2a
grainyhead-like transcription factor 2a
chr21_-_26678542 0.14 ENSDART00000053794
banf1
barrier to autointegration factor 1
chr5_-_68712571 0.14 ENSDART00000109487
CABZ01032476.1
ENSDARG00000074645
chr23_-_3813451 0.13

chr23_-_29897606 0.12 ENSDART00000020616
zgc:194189
zgc:194189
chr23_+_42449089 0.10 ENSDART00000171119
cyp2aa9
cytochrome P450, family 2, subfamily AA, polypeptide 9
chr20_-_21773327 0.08 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr8_+_21974863 0.07

chr23_+_42779461 0.07

chr14_-_30747259 0.06 ENSDART00000002250
hs6st2
heparan sulfate 6-O-sulfotransferase 2
chr9_+_331815 0.06 ENSDART00000170312
actr5
ARP5 actin related protein 5 homolog
chr20_-_23527004 0.05 ENSDART00000004625
zar1
zygote arrest 1
chr16_-_22394481 0.03

chr4_-_12792010 0.03 ENSDART00000067131
irak3
interleukin-1 receptor-associated kinase 3
chr25_+_5233045 0.01

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.7 4.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.2 0.5 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 1.0 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.0 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 2.0 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.1 GO:0042407 cristae formation(GO:0042407)
0.1 0.5 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.1 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 9.5 GO:0007018 microtubule-based movement(GO:0007018)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.6 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.7 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 0.3 GO:0090049 regulation of cell migration involved in sprouting angiogenesis(GO:0090049)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 1.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0019405 alditol catabolic process(GO:0019405)
0.0 0.2 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 1.5 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.0 1.4 GO:0017148 negative regulation of translation(GO:0017148)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.7 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 9.5 GO:0005871 kinesin complex(GO:0005871)
0.1 1.4 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 1.1 GO:0061617 MICOS complex(GO:0061617)
0.1 1.0 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 3.2 GO:0030424 axon(GO:0030424)
0.0 2.0 GO:0005770 late endosome(GO:0005770)
0.0 2.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.0 GO:0005884 actin filament(GO:0005884)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:1903231 mRNA binding involved in posttranscriptional gene silencing(GO:1903231)
0.2 9.5 GO:0003777 microtubule motor activity(GO:0003777)
0.1 0.5 GO:0004936 alpha-adrenergic receptor activity(GO:0004936) alpha1-adrenergic receptor activity(GO:0004937)
0.1 0.6 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 2.0 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 4.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.5 GO:0035197 siRNA binding(GO:0035197)
0.1 3.2 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.3 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 2.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.2 GO:0000993 RNA polymerase II core binding(GO:0000993)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.0 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus