Project
DANIO-CODE
Navigation
Downloads
Results for sox10
Z-value: 1.31
Motif logo
Transcription factors associated with sox10
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| sox10 | dr10_dc_chr3_+_2013046_2013122 | 0.19 | 4.8e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of sox10
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr10_-_45155460 Show fit | 5.05 |
ENSDART00000170767
|
ventrally expressed dharma/bozozok antagonist |
|
| chr1_-_50066633 Show fit | 3.34 |
|
|
|
| chr5_+_26925238 Show fit | 2.68 |
ENSDART00000051491
|
secreted frizzled-related protein 1a |
|
| chr5_-_24982964 Show fit | 2.67 |
ENSDART00000031665
ENSDART00000161043 |
annexin A1a |
|
| chr7_+_24770873 Show fit | 2.43 |
ENSDART00000165314
|
ENSDARG00000103682 |
|
| chr13_+_22545318 Show fit | 2.37 |
ENSDART00000143312
|
zgc:193505 |
|
| chr9_-_18903879 Show fit | 2.35 |
ENSDART00000138785
|
si:dkey-239h2.3 |
|
| chr16_-_51543374 Show fit | 2.13 |
ENSDART00000090530
|
si:ch211-107n13.1 |
|
| chr1_-_50831155 Show fit | 1.93 |
ENSDART00000152719
|
sprouty-related, EVH1 domain containing 2a |
|
| chr6_-_39315024 Show fit | 1.89 |
ENSDART00000012644
|
keratin 4 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 5.1 | GO:0042661 | regulation of mesodermal cell fate specification(GO:0042661) |
| 0.1 | 4.3 | GO:0061386 | closure of optic fissure(GO:0061386) |
| 0.9 | 2.7 | GO:0071887 | positive regulation of adaptive immune response(GO:0002821) positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002824) negative regulation of phospholipase activity(GO:0010519) positive regulation of vesicle fusion(GO:0031340) type 2 immune response(GO:0042092) regulation of fatty acid biosynthetic process(GO:0042304) T-helper 2 cell differentiation(GO:0045064) leukocyte apoptotic process(GO:0071887) regulation of leukocyte apoptotic process(GO:2000106) |
| 0.3 | 2.4 | GO:0033278 | cell proliferation in midbrain(GO:0033278) |
| 0.1 | 2.4 | GO:0007097 | nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023) |
| 0.0 | 2.4 | GO:0048843 | negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668) |
| 0.5 | 1.9 | GO:0010801 | regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801) |
| 0.2 | 1.7 | GO:0021553 | olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628) |
| 0.1 | 1.4 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.0 | 1.4 | GO:0048024 | regulation of mRNA splicing, via spliceosome(GO:0048024) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.5 | GO:0043235 | receptor complex(GO:0043235) |
| 0.3 | 2.7 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.2 | 2.4 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.7 | 2.0 | GO:1990590 | ATF1-ATF4 transcription factor complex(GO:1990590) |
| 0.1 | 1.9 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 1.6 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 1.3 | GO:0005665 | DNA-directed RNA polymerase II, core complex(GO:0005665) DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.1 | 1.1 | GO:0097546 | ciliary base(GO:0097546) |
| 0.1 | 0.9 | GO:0098827 | endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827) |
| 0.0 | 0.7 | GO:0005776 | autophagosome(GO:0005776) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.3 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.1 | 3.0 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.3 | 2.7 | GO:0055102 | phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102) |
| 0.0 | 2.4 | GO:0045499 | semaphorin receptor binding(GO:0030215) chemorepellent activity(GO:0045499) |
| 0.1 | 2.3 | GO:0019209 | kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295) |
| 0.0 | 2.3 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 1.9 | GO:0019901 | protein kinase binding(GO:0019901) |
| 0.2 | 1.6 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.1 | 1.6 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393) |
| 0.1 | 1.5 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.7 | PID FGF PATHWAY | FGF signaling pathway |
| 0.0 | 1.4 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 0.9 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.0 | 0.8 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.1 | 0.7 | SIG PIP3 SIGNALING IN B LYMPHOCYTES | Genes related to PIP3 signaling in B lymphocytes |
| 0.0 | 0.7 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 0.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.0 | 0.4 | PID IL8 CXCR2 PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.0 | 0.3 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 0.2 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 2.4 | REACTOME FGFR2C LIGAND BINDING AND ACTIVATION | Genes involved in FGFR2c ligand binding and activation |
| 0.6 | 1.8 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.0 | 1.4 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 1.3 | REACTOME VIRAL MESSENGER RNA SYNTHESIS | Genes involved in Viral Messenger RNA Synthesis |
| 0.1 | 1.0 | REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE | Genes involved in Amino acid transport across the plasma membrane |
| 0.1 | 0.9 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.9 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 0.8 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 0.8 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.0 | 0.7 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |