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DANIO-CODE

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Results for sox10

Z-value: 1.31

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Transcription factors associated with sox10

Gene Symbol Gene ID Gene Info
sox10
ENSDARG00000077467 SRY-box transcription factor 10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox10dr10_dc_chr3_+_2013046_20131220.194.8e-01Click!

Activity profile of sox10 motif

Sorted Z-values of sox10 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of sox10

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_-_45155460 5.05 ENSDART00000170767
ved
ventrally expressed dharma/bozozok antagonist
chr1_-_50066633 3.34

chr5_+_26925238 2.68 ENSDART00000051491
sfrp1a
secreted frizzled-related protein 1a
chr5_-_24982964 2.67 ENSDART00000031665
ENSDART00000161043
anxa1a
annexin A1a
chr7_+_24770873 2.43 ENSDART00000165314
AL954715.1
ENSDARG00000103682
chr13_+_22545318 2.37 ENSDART00000143312
zgc:193505
zgc:193505
chr9_-_18903879 2.35 ENSDART00000138785
si:dkey-239h2.3
si:dkey-239h2.3
chr16_-_51543374 2.13 ENSDART00000090530
si:ch211-107n13.1
si:ch211-107n13.1
chr1_-_50831155 1.93 ENSDART00000152719
spred2a
sprouty-related, EVH1 domain containing 2a
chr6_-_39315024 1.89 ENSDART00000012644
krt4
keratin 4
chr3_+_24067387 1.85 ENSDART00000055609
atf4b
activating transcription factor 4b
chr16_+_4825019 1.78 ENSDART00000167665
LIN28A
lin-28 homolog A
chr8_-_38168395 1.70 ENSDART00000155189
pdlim2
PDZ and LIM domain 2 (mystique)
chr15_-_1625846 1.69 ENSDART00000081875
nnr
nanor
chr18_+_40365208 1.66 ENSDART00000167134
sema6dl
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like
chr25_-_34616997 1.63 ENSDART00000137502
si:ch73-36p18.1
si:ch73-36p18.1
chr1_-_31123999 1.61 ENSDART00000152493
nt5c2b
5'-nucleotidase, cytosolic IIb
chr1_-_18695214 1.56

chr23_-_24468191 1.51 ENSDART00000044918
epha2b
eph receptor A2 b
chr1_+_16683931 1.50 ENSDART00000103262
ENSDART00000145068
ENSDART00000169619
ENSDART00000010526
fat1a
FAT atypical cadherin 1a
chr23_+_24711233 1.50

chr17_-_43896998 1.43 ENSDART00000156513
BX465227.1
ENSDARG00000097825
chr13_-_33137075 1.39 ENSDART00000138096
oip5-as1
oip5 antisense RNA 1
chr8_-_50992034 1.39 ENSDART00000004065
zgc:91909
zgc:91909
chr7_+_56076854 1.38

chr4_-_11604184 1.38 ENSDART00000170136
net1
neuroepithelial cell transforming 1
chr20_-_21773202 1.35 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr22_+_17091411 1.31 ENSDART00000170076
frem1b
Fras1 related extracellular matrix 1b
chr8_-_16662185 1.30 ENSDART00000076542
rpe65b
retinal pigment epithelium-specific protein 65b
chr14_-_30556788 1.29 ENSDART00000087918
slc7a3b
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3b
chr3_-_16100715 1.28 ENSDART00000146699
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr13_-_46292762 1.28 ENSDART00000149125
fgfr2
fibroblast growth factor receptor 2
chr18_-_5796081 1.26 ENSDART00000097696
ENSDART00000151453
si:ch1073-459b3.2
si:ch1073-459b3.2
chr22_-_36561247 1.26 ENSDART00000056188
polr2h
info polymerase (RNA) II (DNA directed) polypeptide H
chr4_-_7721419 1.22

chr21_-_44610563 1.20 ENSDART00000099528
spry4
sprouty homolog 4 (Drosophila)
chr1_+_27174549 1.20 ENSDART00000102337
dnajb14
DnaJ (Hsp40) homolog, subfamily B, member 14
KN149859v1_+_16751 1.13 ENSDART00000167610
ENSDARG00000103399
ENSDARG00000103399
chr3_+_30962542 1.12 ENSDART00000153074
si:dkey-66i24.9
si:dkey-66i24.9
chr25_-_12691849 1.12 ENSDART00000158551
slc7a5
solute carrier family 7 (amino acid transporter light chain, L system), member 5
chr17_-_48722470 1.12 ENSDART00000160893
kif6
kinesin family member 6
chr6_-_43094573 1.12 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr22_+_14073249 1.11 ENSDART00000080335
ENSDART00000018432
he1b
hatching enzyme 1b
chr14_-_31184501 1.09

chr14_-_7774262 1.09 ENSDART00000045109
zgc:92242
zgc:92242
chr20_-_21773327 1.08 ENSDART00000133286
si:ch211-207i1.2
si:ch211-207i1.2
chr2_-_22692538 1.07

chr17_+_24830545 1.05 ENSDART00000062917
cx35.4
connexin 35.4
chr13_-_13163676 1.03 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
chr14_+_38505346 1.02 ENSDART00000129958
ENSDART00000144599
hnrnpa0b
heterogeneous nuclear ribonucleoprotein A0b
chr5_+_56885728 1.02

chr18_-_782643 1.01 ENSDART00000161084
si:dkey-205h23.1
si:dkey-205h23.1
chr25_+_31457309 0.94 ENSDART00000022325
parp16
poly (ADP-ribose) polymerase family, member 16
chr5_-_14148028 0.93 ENSDART00000113037
sema4c
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr3_-_26073676 0.92 ENSDART00000169123
gdpd3a
glycerophosphodiester phosphodiesterase domain containing 3a
chr3_-_38642067 0.92 ENSDART00000155518
znf281a
zinc finger protein 281a
chr23_+_18565721 0.91

chr13_+_1051015 0.88 ENSDART00000033528
tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr8_-_52729505 0.87 ENSDART00000168241
tubb2b
tubulin, beta 2b
chr9_+_36023553 0.86 ENSDART00000122169
si:dkey-67c22.2
si:dkey-67c22.2
chr22_-_15567180 0.86 ENSDART00000123125
tpm4a
tropomyosin 4a
chr1_-_44009572 0.85 ENSDART00000144900
ENSDARG00000079632
ENSDARG00000079632
chr20_+_29307142 0.81 ENSDART00000153016
katnbl1
katanin p80 subunit B-like 1
chr22_-_3661536 0.81 ENSDART00000153634
FP565432.1
ENSDARG00000097145
chr12_-_30662709 0.81 ENSDART00000126466
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr5_-_43686611 0.81 ENSDART00000146080
si:ch73-337l15.2
si:ch73-337l15.2
chr19_-_3208938 0.80

chr19_+_31817286 0.79 ENSDART00000078459
tmem55a
transmembrane protein 55A
chr8_+_2517472 0.79 ENSDART00000112914
si:ch211-51h9.7
si:ch211-51h9.7
chr7_-_2367001 0.78 ENSDART00000174011
si:cabz01007812.1
si:cabz01007812.1
chr11_+_6138968 0.76 ENSDART00000082223
tax1bp3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr21_-_25719352 0.74 ENSDART00000002341
cldnc
claudin c
chr2_-_43110857 0.74 ENSDART00000098303
oc90
otoconin 90
chr14_+_35880163 0.73 ENSDART00000148319
pitx2
paired-like homeodomain 2
chr8_+_23334921 0.73 ENSDART00000085361
ENSDART00000046460
ENSDART00000145062
dnmt3ba
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a
chr20_-_22576513 0.73 ENSDART00000103510
pdgfra
platelet-derived growth factor receptor, alpha polypeptide
chr12_+_31623806 0.73

chr13_-_46292975 0.72 ENSDART00000167402
ENSDART00000080914
ENSDART00000080916
fgfr2
fibroblast growth factor receptor 2
chr6_-_27963880 0.72 ENSDART00000163747
BX914220.1
ENSDARG00000098603
chr10_+_45138195 0.72 ENSDART00000162566
h2afvb
H2A histone family, member Vb
chr1_-_50576110 0.71 ENSDART00000146612
esf1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr16_+_40610589 0.71 ENSDART00000038294
tp53inp1
tumor protein p53 inducible nuclear protein 1
chr4_+_50923792 0.70 ENSDART00000161370
BX640547.3
ENSDARG00000100076
chr3_-_58590651 0.70 ENSDART00000057640
dhrs7ca
dehydrogenase/reductase (SDR family) member 7Ca
chr6_-_49512935 0.69 ENSDART00000166238
rplp2
ribosomal protein, large P2
chr3_+_30962827 0.68 ENSDART00000153074
si:dkey-66i24.9
si:dkey-66i24.9
chr17_+_1986151 0.67 ENSDART00000103775
pak6a
p21 protein (Cdc42/Rac)-activated kinase 6a
chr9_-_34491458 0.65 ENSDART00000049805
ildr2
immunoglobulin-like domain containing receptor 2
chr17_+_24045786 0.65 ENSDART00000132755
b3gnt2b
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2b
chr13_-_13163801 0.65 ENSDART00000156968
fgfr3
fibroblast growth factor receptor 3
chr6_+_10491884 0.64 ENSDART00000151017
BX936397.2
ENSDARG00000096373
chr7_-_6281491 0.64 ENSDART00000172795
si:ch73-368j24.12
si:ch73-368j24.12
chr21_-_39900518 0.63 ENSDART00000175055
CABZ01065291.1
ENSDARG00000107374
chr15_-_17818432 0.63 ENSDART00000157198
CT573342.1
ENSDARG00000097333
chr16_+_53238110 0.59 ENSDART00000102170
CABZ01053976.1
ENSDARG00000069929
chr16_-_26858511 0.58 ENSDART00000135860
rnf41l
ring finger protein 41, like
chr6_-_43094926 0.57 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr11_+_37345024 0.57 ENSDART00000077496
hp1bp3
heterochromatin protein 1, binding protein 3
chr9_+_36023025 0.55 ENSDART00000122169
si:dkey-67c22.2
si:dkey-67c22.2
chr10_-_8336541 0.55 ENSDART00000163803
plpp1a
phospholipid phosphatase 1a
chr11_+_30048913 0.54

chr7_+_20008453 0.53 ENSDART00000012450
dvl2
dishevelled segment polarity protein 2
chr18_+_45564871 0.53

chr12_+_18622682 0.53 ENSDART00000153456
mkl1b
megakaryoblastic leukemia (translocation) 1b
chr20_-_25726868 0.53 ENSDART00000126716
paics
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr25_+_20618512 0.51 ENSDART00000144748
ergic2
ERGIC and golgi 2
chr11_+_30049041 0.50

chr5_+_25521198 0.50 ENSDART00000002221
bco2l
beta-carotene 15, 15-dioxygenase 2, like
chr7_+_49391403 0.50 ENSDART00000131210
rassf7b
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7b
chr22_-_20284307 0.49 ENSDART00000159604
mbd3b
methyl-CpG binding domain protein 3b
chr11_+_25063488 0.48

chr1_-_23603046 0.48

chr9_+_38975508 0.48

chr7_-_71092394 0.48 ENSDART00000081245
dhx15
DEAH (Asp-Glu-Ala-His) box helicase 15
chr7_+_19583578 0.47 ENSDART00000149812
ovol1
ovo-like zinc finger 1
chr5_+_39619826 0.47 ENSDART00000114078
si:dkey-193c22.2
si:dkey-193c22.2
chr14_+_38509121 0.46 ENSDART00000052511
hnrnpa0l
heterogeneous nuclear ribonucleoprotein A0, like
chr2_-_42510909 0.46 ENSDART00000144274
si:dkey-7l6.3
si:dkey-7l6.3
chr5_-_51351827 0.45 ENSDART00000097194
serinc5
serine incorporator 5
chr20_-_47123598 0.45 ENSDART00000100320
dnmt3aa
DNA (cytosine-5-)-methyltransferase 3 alpha a
chr8_-_12171624 0.45 ENSDART00000132824
dab2ipa
DAB2 interacting protein a
chr13_-_46292862 0.45 ENSDART00000150061
fgfr2
fibroblast growth factor receptor 2
chr22_-_18521227 0.45 ENSDART00000105404
cirbpb
cold inducible RNA binding protein b
chr21_-_25704662 0.44 ENSDART00000101211
cldnh
claudin h
chr17_-_6191539 0.44 ENSDART00000081707
ENSDARG00000058775
ENSDARG00000058775
chr15_-_16140187 0.43 ENSDART00000080413
srsf1a
serine/arginine-rich splicing factor 1a
chr19_-_18689571 0.43 ENSDART00000016135
nfe2l3
nuclear factor, erythroid 2-like 3
chr25_-_35820568 0.42 ENSDART00000152766
CR354435.4
Histone H2B 1/2
chr20_+_52778914 0.41 ENSDART00000138641
si:dkey-235d18.5
si:dkey-235d18.5
chr19_-_18315998 0.41 ENSDART00000151133
top2b
topoisomerase (DNA) II beta
chr19_+_13492428 0.41 ENSDART00000165033
srsf4
serine/arginine-rich splicing factor 4
chr19_-_3208863 0.40

chr23_+_44782492 0.40 ENSDART00000125198
pfn1
profilin 1
chr17_-_20216303 0.39 ENSDART00000029380
bnip4
BCL2/adenovirus E1B interacting protein 4
KN149932v1_+_27584 0.39

chr7_-_6323808 0.39 ENSDART00000173158
zgc:112234
zgc:112234
chr11_-_18016658 0.39

chr11_+_14263376 0.39 ENSDART00000132997
ptbp1b
polypyrimidine tract binding protein 1b
chr3_+_15355472 0.38 ENSDART00000141714
nupr1
nuclear protein 1
chr11_-_2227358 0.38 ENSDART00000018131
hnrnpa1a
heterogeneous nuclear ribonucleoprotein A1a
chr14_-_50145578 0.38 ENSDART00000042421
ppp2ca
protein phosphatase 2, catalytic subunit, alpha isozyme
chr20_-_25731057 0.38

chr18_-_38235232 0.37 ENSDART00000114224
si:dkey-10o6.2
si:dkey-10o6.2
chr16_-_36061564 0.36 ENSDART00000175847
CABZ01065723.1
ENSDARG00000105999
chr7_-_71290605 0.36 ENSDART00000111797
acer2
alkaline ceramidase 2
chr2_+_39653315 0.36 ENSDART00000077108
zgc:136870
zgc:136870
chr14_-_38487071 0.36 ENSDART00000160000
spdl1
spindle apparatus coiled-coil protein 1
chr6_-_9471808 0.36 ENSDART00000039280
fzd7b
frizzled class receptor 7b
chr7_-_57030751 0.35

chr20_+_25669615 0.35 ENSDART00000063107
cyp2p7
cytochrome P450, family 2, subfamily P, polypeptide 7
chr5_+_69401770 0.35

chr4_+_33077499 0.34

chr19_+_42863138 0.34 ENSDART00000076938
pogza
pogo transposable element derived with ZNF domain a
chr22_+_2681009 0.34

chr13_-_7897936 0.34 ENSDART00000139728
si:ch211-250c4.4
si:ch211-250c4.4
chr9_-_19951894 0.33 ENSDART00000146841
si:ch211-141e20.2
si:ch211-141e20.2
chr6_-_120518 0.33 ENSDART00000148911
keap1b
kelch-like ECH-associated protein 1b
chr17_-_14697094 0.33 ENSDART00000154281
ptp4a2a
protein tyrosine phosphatase type IVA, member 2a
chr12_-_20493683 0.33

chr25_+_35784213 0.33 ENSDART00000152761
CR354435.7
ENSDARG00000094744
chr19_+_15617624 0.32 ENSDART00000003164
ppp1r8a
protein phosphatase 1, regulatory subunit 8a
chr11_-_17620732 0.32 ENSDART00000154627
eogt
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr18_+_38793474 0.32 ENSDART00000059208
fam214a
family with sequence similarity 214, member A
chr7_+_71262935 0.32 ENSDART00000100396
ppp1r15a
protein phosphatase 1, regulatory subunit 15A
chr3_+_62051743 0.32 ENSDART00000168063
zgc:173575
zgc:173575
chr2_+_2930605 0.32 ENSDART00000124882
thoc1
THO complex 1
chr19_+_43448344 0.31 ENSDART00000015632
nkain1
sodium/potassium transporting ATPase interacting 1
chr5_+_69096325 0.31 ENSDART00000014649
ugt2a5
UDP glucuronosyltransferase 2 family, polypeptide A5
chr3_+_62081343 0.31 ENSDART00000058719
znf1124
zinc finger protein 1124
chr9_-_9264634 0.31 ENSDART00000021191
u2af1
U2 small nuclear RNA auxiliary factor 1
chr19_-_29205158 0.30 ENSDART00000026992
sox4a
SRY (sex determining region Y)-box 4a
chr21_-_767364 0.30 ENSDART00000130648
scarb2c
scavenger receptor class B, member 2c
chr19_+_19330545 0.30 ENSDART00000157523
slc39a7
solute carrier family 39 (zinc transporter), member 7
chr9_-_23346038 0.30 ENSDART00000135461
lypd6b
LY6/PLAUR domain containing 6B
chr16_+_51319421 0.30

chr20_+_49975268 0.30 ENSDART00000008808
hmbox1b
homeobox containing 1 b
chr14_+_10350292 0.29 ENSDART00000127594
atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr7_+_20008083 0.29 ENSDART00000012450
dvl2
dishevelled segment polarity protein 2
chr8_+_8934762 0.28 ENSDART00000133137
bcap31
B-cell receptor-associated protein 31
chr18_+_40535215 0.28 ENSDART00000132833
vwa7
von Willebrand factor A domain containing 7
chr7_+_40879017 0.28

chr15_+_43192811 0.28

chr5_+_64411584 0.27 ENSDART00000158484
BX001023.2
ENSDARG00000101163
chr19_+_20199890 0.27 ENSDART00000161019
hoxa4a
homeobox A4a
chr24_+_14095643 0.27 ENSDART00000124740
ncoa2
nuclear receptor coactivator 2
chr9_-_39190534 0.27

chr14_+_6122644 0.26 ENSDART00000149783
ENSDART00000148461
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr11_+_37453275 0.26 ENSDART00000050296
snrpe
small nuclear ribonucleoprotein polypeptide E
chr21_-_28883441 0.26 ENSDART00000132884
cxxc5a
CXXC finger protein 5a
chr18_-_36291301 0.25

chr4_+_29775735 0.25 ENSDART00000166510
BX530097.1
ENSDARG00000104762
chr21_+_37405904 0.24 ENSDART00000148956
znf346
zinc finger protein 346
chr18_+_41537683 0.24 ENSDART00000146972
selt1b
selenoprotein T, 1b
chr16_-_31664756 0.24 ENSDART00000176939
phf20l1
PHD finger protein 20-like 1
chr24_+_16402613 0.24 ENSDART00000164319
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr16_-_33151504 0.24 ENSDART00000145055
pnrc2
proline-rich nuclear receptor coactivator 2
chr21_-_25704793 0.23 ENSDART00000101211
cldnh
claudin h
chr23_+_2391317 0.23

chr10_-_43815475 0.23 ENSDART00000027392
mef2ca
myocyte enhancer factor 2ca
chr13_+_25298383 0.23

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0071887 positive regulation of adaptive immune response(GO:0002821) positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002824) negative regulation of phospholipase activity(GO:0010519) positive regulation of vesicle fusion(GO:0031340) type 2 immune response(GO:0042092) regulation of fatty acid biosynthetic process(GO:0042304) T-helper 2 cell differentiation(GO:0045064) leukocyte apoptotic process(GO:0071887) regulation of leukocyte apoptotic process(GO:2000106)
0.5 1.9 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.5 5.1 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.4 1.3 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.3 2.4 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.3 0.9 GO:0071947 protein K29-linked deubiquitination(GO:0035523) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.2 1.7 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.2 0.8 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.2 0.7 GO:0061072 iris morphogenesis(GO:0061072)
0.2 0.5 GO:0016121 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.1 0.7 GO:1903963 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.1 0.8 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.1 2.4 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 1.2 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.1 0.8 GO:0090179 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 4.3 GO:0061386 closure of optic fissure(GO:0061386)
0.1 1.4 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 0.7 GO:0003315 heart rudiment formation(GO:0003315)
0.1 0.5 GO:0038026 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948) reelin-mediated signaling pathway(GO:0038026)
0.1 0.4 GO:0071459 protein localization to kinetochore(GO:0034501) protein localization to chromosome, centromeric region(GO:0071459)
0.1 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.3 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 0.3 GO:0010922 positive regulation of phosphatase activity(GO:0010922) positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 1.0 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 0.2 GO:0001502 cartilage condensation(GO:0001502) cell aggregation(GO:0098743)
0.1 0.2 GO:0044806 multicellular organism aging(GO:0010259) G-quadruplex DNA unwinding(GO:0044806)
0.1 1.3 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.1 0.5 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 0.8 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.2 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 1.2 GO:0051788 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.4 GO:0007412 axon target recognition(GO:0007412)
0.0 2.4 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.6 GO:0070828 heterochromatin organization(GO:0070828)
0.0 0.5 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.1 GO:0008347 glial cell migration(GO:0008347)
0.0 0.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.6 GO:0009409 response to cold(GO:0009409) positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.2 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.4 GO:1902110 positive regulation of mitochondrial membrane permeability(GO:0035794) mitochondrial outer membrane permeabilization(GO:0097345) positive regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902110) mitochondrial outer membrane permeabilization involved in programmed cell death(GO:1902686)
0.0 1.2 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 0.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 1.0 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0031294 lymphocyte costimulation(GO:0031294) T cell costimulation(GO:0031295)
0.0 0.3 GO:0033700 phospholipid efflux(GO:0033700)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0071577 cellular zinc ion homeostasis(GO:0006882) zinc ion homeostasis(GO:0055069) zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.7 GO:0060037 pharyngeal system development(GO:0060037)
0.0 0.3 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.1 GO:0045887 regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887) positive regulation of neuromuscular junction development(GO:1904398)
0.0 0.4 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.1 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.0 0.2 GO:0009743 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0035308 negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.0 1.4 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 1.4 GO:0021510 spinal cord development(GO:0021510)
0.0 0.3 GO:0042738 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)
0.0 0.8 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.7 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 0.1 GO:0010002 cardioblast differentiation(GO:0010002)
0.0 0.6 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.7 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.4 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.3 GO:0032784 regulation of DNA-templated transcription, elongation(GO:0032784)
0.0 0.1 GO:0016137 glycoside metabolic process(GO:0016137) glycoside catabolic process(GO:0016139)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0002028 regulation of sodium ion transport(GO:0002028)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.3 2.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 2.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.9 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 0.3 GO:0034709 methylosome(GO:0034709)
0.1 1.1 GO:0097546 ciliary base(GO:0097546)
0.1 1.9 GO:0045095 keratin filament(GO:0045095)
0.1 0.4 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.1 1.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665) DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.3 GO:0016234 inclusion body(GO:0016234)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0005883 neurofilament(GO:0005883)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 6.5 GO:0043235 receptor complex(GO:0043235)
0.0 0.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.5 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.2 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 0.5 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.7 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.3 2.7 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.3 4.3 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 1.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 0.5 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.1 0.4 GO:0043515 kinetochore binding(GO:0043515)
0.1 1.5 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.5 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 0.3 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 0.4 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.7 GO:0004623 phospholipase A2 activity(GO:0004623)
0.1 0.8 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 1.0 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 1.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 3.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 1.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 2.3 GO:0019209 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.1 0.8 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 0.2 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 2.4 GO:0045499 semaphorin receptor binding(GO:0030215) chemorepellent activity(GO:0045499)
0.0 0.3 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.2 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.0 GO:0015179 L-amino acid transmembrane transporter activity(GO:0015179)
0.0 0.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 0.1 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 2.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.9 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.3 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID FGF PATHWAY FGF signaling pathway
0.1 0.7 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.0 0.9 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.7 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.4 2.4 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.1 1.3 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 1.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 0.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.8 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway