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Results for sox12

Z-value: 0.33

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Transcription factors associated with sox12

Gene Symbol Gene ID Gene Info
sox12
ENSDARG00000025847 SRY-box transcription factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox12dr10_dc_chr11_-_23954234_23954320-0.476.6e-02Click!

Activity profile of sox12 motif

Sorted Z-values of sox12 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of sox12

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr10_-_32716794 0.34 ENSDART00000141013
atg101
autophagy related 101
chr20_-_14218080 0.30 ENSDART00000104032
si:ch211-223m11.2
si:ch211-223m11.2
chr17_-_23689233 0.29 ENSDART00000124661
papss2a
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr20_+_1364879 0.27 ENSDART00000145981
ENSDART00000152709
mmachc
methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria
chr17_+_7377230 0.27 ENSDART00000157123
shprh
SNF2 histone linker PHD RING helicase
chr7_-_24249672 0.26 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr8_+_54034258 0.26 ENSDART00000170712
ENSDART00000164153
BRPF1
bromodomain and PHD finger containing 1
chr7_-_28293919 0.25 ENSDART00000028887
tmem9b
TMEM9 domain family, member B
chr2_-_31849916 0.24 ENSDART00000109460
nol7
nucleolar protein 7
chr12_-_22279843 0.23 ENSDART00000153194
si:dkey-38p12.3
si:dkey-38p12.3
chr6_+_29763568 0.22 ENSDART00000151784
ptmaa
prothymosin, alpha a
chr22_-_746251 0.22 ENSDART00000061775
rbbp5
retinoblastoma binding protein 5
chr5_-_23727236 0.22 ENSDART00000143492
senp3a
SUMO1/sentrin/SMT3 specific peptidase 3a
chr16_-_16329761 0.22 ENSDART00000111912
rbm12b
RNA binding motif protein 12B
chr2_-_56933166 0.22 ENSDART00000167441
ARMC6
armadillo repeat containing 6
chr14_+_45685886 0.22

chr24_-_41403824 0.21 ENSDART00000063504
ENSDART00000169374
xylb
xylulokinase homolog (H. influenzae)
chr3_-_15960288 0.20 ENSDART00000051807
lasp1
LIM and SH3 protein 1
chr16_-_10006640 0.20 ENSDART00000104058
ncalda
neurocalcin delta a
chr24_-_2453890 0.20 ENSDART00000093331
rreb1a
ras responsive element binding protein 1a
chr7_-_24724911 0.20 ENSDART00000173791
rcor2
REST corepressor 2
chr18_+_8954323 0.20 ENSDART00000134827
tmem243a
transmembrane protein 243, mitochondrial a
chr6_-_12787256 0.19 ENSDART00000157139
tmbim1a
transmembrane BAX inhibitor motif containing 1a
chr22_+_21593142 0.19 ENSDART00000133939
tle2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr3_-_15960491 0.19 ENSDART00000064838
lasp1
LIM and SH3 protein 1
chr8_-_19283046 0.18 ENSDART00000164780
rgl1
ral guanine nucleotide dissociation stimulator-like 1
chr24_+_37810878 0.18 ENSDART00000066556
zmp:0000000624
zmp:0000000624
chr17_-_25284710 0.18 ENSDART00000167992
ppie
peptidylprolyl isomerase E (cyclophilin E)
chr18_+_6339577 0.18 ENSDART00000136333
wash1
WAS protein family homolog 1
chr14_-_21320696 0.17 ENSDART00000043162
reep2
receptor accessory protein 2
chr5_-_23727210 0.17 ENSDART00000143492
senp3a
SUMO1/sentrin/SMT3 specific peptidase 3a
chr3_+_10182687 0.17 ENSDART00000156700
cbx2
chromobox homolog 2 (Drosophila Pc class)
chr10_-_32716718 0.16 ENSDART00000063544
atg101
autophagy related 101
chr17_+_51851738 0.16 ENSDART00000053422
ttll5
tubulin tyrosine ligase-like family, member 5
chr4_-_3014778 0.16 ENSDART00000128934
ENSDART00000019518
aebp2
AE binding protein 2
chr4_-_17028492 0.16

chr20_+_14218237 0.15 ENSDART00000044937
kcns3b
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3b
chr16_+_12922320 0.15 ENSDART00000008535
u2af2a
U2 small nuclear RNA auxiliary factor 2a
chr18_+_8954512 0.14 ENSDART00000134827
tmem243a
transmembrane protein 243, mitochondrial a
chr13_+_35639424 0.14 ENSDART00000100156
agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr3_+_10182994 0.14 ENSDART00000156700
cbx2
chromobox homolog 2 (Drosophila Pc class)
chr22_+_21593704 0.14

chr15_+_27000467 0.14 ENSDART00000023842
ppm1da
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr16_+_12922781 0.13 ENSDART00000008535
u2af2a
U2 small nuclear RNA auxiliary factor 2a
chr3_+_40142679 0.13 ENSDART00000009411
bud31
BUD31 homolog (S. cerevisiae)
chr16_-_26633959 0.13 ENSDART00000139663
CR391910.2
ENSDARG00000093592
chr22_-_746441 0.13 ENSDART00000061775
rbbp5
retinoblastoma binding protein 5
chr3_-_35734943 0.13 ENSDART00000135957
suz12a
SUZ12 polycomb repressive complex 2a subunit
chr17_-_25284780 0.12 ENSDART00000167992
ppie
peptidylprolyl isomerase E (cyclophilin E)
chr6_-_12787356 0.12 ENSDART00000157139
tmbim1a
transmembrane BAX inhibitor motif containing 1a
chr17_+_30826890 0.12 ENSDART00000149600
tpp1
tripeptidyl peptidase I
chr17_-_23689380 0.12 ENSDART00000124661
papss2a
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr12_-_22279890 0.12 ENSDART00000153194
si:dkey-38p12.3
si:dkey-38p12.3
chr17_-_23689317 0.12 ENSDART00000124661
papss2a
3'-phosphoadenosine 5'-phosphosulfate synthase 2a
chr17_+_15528691 0.12

chr3_-_35735315 0.12 ENSDART00000102952
suz12a
SUZ12 polycomb repressive complex 2a subunit
chr14_-_49973159 0.12 ENSDART00000124192
si:dkeyp-121d2.7
si:dkeyp-121d2.7
chr2_-_31850133 0.12 ENSDART00000109460
nol7
nucleolar protein 7
chr7_+_28844711 0.11 ENSDART00000052345
tradd
tnfrsf1a-associated via death domain
chr5_-_37784663 0.11 ENSDART00000051233
mink1
misshapen-like kinase 1
chr17_-_7377094 0.11

chr1_+_40784540 0.11 ENSDART00000142508
si:ch211-89o9.6
si:ch211-89o9.6
chr18_+_14368973 0.11

chr23_+_30803887 0.11 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr14_-_6637670 0.10 ENSDART00000126279
clk4a
CDC-like kinase 4a
chr2_-_56933194 0.10 ENSDART00000178179
ARMC6
armadillo repeat containing 6
chr5_-_27549500 0.10 ENSDART00000051515
zgc:110329
zgc:110329
chr2_-_24413154 0.10 ENSDART00000145526
slc12a7a
solute carrier family 12 (potassium/chloride transporter), member 7a
chr7_-_24249630 0.10 ENSDART00000077039
faah2b
fatty acid amide hydrolase 2b
chr22_-_746334 0.10 ENSDART00000061775
rbbp5
retinoblastoma binding protein 5
chr10_+_5267937 0.09 ENSDART00000114491
ror2
receptor tyrosine kinase-like orphan receptor 2
chr8_+_54034431 0.09 ENSDART00000170712
ENSDART00000164153
BRPF1
bromodomain and PHD finger containing 1
chr6_+_46404956 0.09 ENSDART00000131203
ENSDART00000103472
ENSDART00000132845
ENSDART00000138567
ENSDART00000168440
pbrm1l
polybromo 1, like
chr15_-_28654137 0.09 ENSDART00000156049
ssh2a
slingshot protein phosphatase 2a
chr5_+_25620803 0.09 ENSDART00000007587
gtf2h2
general transcription factor IIH, polypeptide 2
chr22_+_39012456 0.08 ENSDART00000176985
CABZ01044615.1
ENSDARG00000108810
chr9_-_34145854 0.08

chr21_-_26369503 0.08 ENSDART00000137312
eif4ebp3
eukaryotic translation initiation factor 4E binding protein 3
chr7_-_24724452 0.08 ENSDART00000173791
rcor2
REST corepressor 2
chr6_-_12786937 0.08 ENSDART00000157139
tmbim1a
transmembrane BAX inhibitor motif containing 1a
chr12_-_22279713 0.07 ENSDART00000153194
si:dkey-38p12.3
si:dkey-38p12.3
chr10_+_5268009 0.07 ENSDART00000114491
ror2
receptor tyrosine kinase-like orphan receptor 2
chr24_+_26223767 0.07

chr2_-_56933086 0.07 ENSDART00000167441
ARMC6
armadillo repeat containing 6
chr20_+_31372117 0.07

chr6_-_55287399 0.07

chr23_+_30803518 0.07 ENSDART00000134141
asxl1
additional sex combs like transcriptional regulator 1
chr1_-_25838798 0.07

chr5_+_44538762 0.07 ENSDART00000172702
ENSDART00000136002
smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_-_28293954 0.06 ENSDART00000028887
tmem9b
TMEM9 domain family, member B
chr6_+_27676886 0.06 ENSDART00000159624
ENSDART00000049177
rab6ba
RAB6B, member RAS oncogene family a
chr9_+_25109716 0.06 ENSDART00000037025
slc39a10
solute carrier family 39 (zinc transporter), member 10
chr1_-_33694144 0.06

chr4_+_28374965 0.06 ENSDART00000150424
si:ch73-263o4.4
si:ch73-263o4.4
chr20_-_14218236 0.06 ENSDART00000168434
si:ch211-223m11.2
si:ch211-223m11.2
chr15_+_27000248 0.06 ENSDART00000023842
ppm1da
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr9_-_46609555 0.05

chr8_-_9531866 0.05 ENSDART00000044000
plxna3
plexin A3
chr23_-_36349563 0.05

chr6_-_11594818 0.05 ENSDART00000151602
AL929243.1
ENSDARG00000096290
chr13_+_35639263 0.05 ENSDART00000100156
agpat4
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr13_+_4040744 0.05

chr17_+_23102283 0.04 ENSDART00000138069
rasgrp3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr17_+_15528825 0.04

chr11_+_23657658 0.04 ENSDART00000160394
CR354444.2
ENSDARG00000103549
chr5_-_68712571 0.03 ENSDART00000109487
CABZ01032476.1
ENSDARG00000074645
chr7_-_26653629 0.03 ENSDART00000124363
alx4a
ALX homeobox 4a
chr7_+_38395803 0.03 ENSDART00000013394
mtch2
mitochondrial carrier homolog 2
chr6_+_46404650 0.03 ENSDART00000131203
ENSDART00000103472
ENSDART00000132845
ENSDART00000138567
ENSDART00000168440
pbrm1l
polybromo 1, like
chr24_-_37793048 0.03 ENSDART00000078828
ENSDART00000131342
anks3
ankyrin repeat and sterile alpha motif domain containing 3
chr22_+_21593358 0.03 ENSDART00000133939
tle2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr23_-_36350288 0.03 ENSDART00000110478
zgc:174906
zgc:174906
chr23_-_26799063 0.02 ENSDART00000157844
hspg2
heparan sulfate proteoglycan 2
chr3_-_35735085 0.02 ENSDART00000135957
suz12a
SUZ12 polycomb repressive complex 2a subunit
chr17_+_7377152 0.02 ENSDART00000157123
shprh
SNF2 histone linker PHD RING helicase
chr17_+_23102259 0.02 ENSDART00000178403
rasgrp3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr19_-_3208863 0.02

chr17_-_37040694 0.01 ENSDART00000126823
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr5_-_68712851 0.01 ENSDART00000109487
CABZ01032476.1
ENSDARG00000074645
chr13_+_9227395 0.01 ENSDART00000047740
wdr32
WD repeat domain 32
chr18_+_44635321 0.01

chr9_-_33116897 0.01

chr7_-_26653672 0.01 ENSDART00000124363
alx4a
ALX homeobox 4a
chr15_+_27000663 0.01 ENSDART00000023842
ppm1da
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
chr18_-_14368801 0.01 ENSDART00000164100
hsbp1b
heat shock factor binding protein 1b
chr4_-_13568618 0.00 ENSDART00000169582
mdm1
Mdm1 nuclear protein homolog (mouse)
chr1_+_45817971 0.00

chr15_-_1519571 0.00 ENSDART00000129356
si:dkeyp-97b10.3
si:dkeyp-97b10.3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0050427 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 0.2 GO:0005997 xylulose metabolic process(GO:0005997)
0.0 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.2 GO:0046660 female sex differentiation(GO:0046660)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0048755 branching morphogenesis of a nerve(GO:0048755)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0035517 PR-DUB complex(GO:0035517)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0016586 RSC complex(GO:0016586)
0.0 0.2 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.5 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.3 GO:0000792 heterochromatin(GO:0000792)
0.0 0.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.2 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004020 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.2 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.3 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0070739 protein-glutamic acid ligase activity(GO:0070739) tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis