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Results for sox14

Z-value: 1.10

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Transcription factors associated with sox14

Gene Symbol Gene ID Gene Info
sox14
ENSDARG00000070929 SRY-box transcription factor 14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox14dr10_dc_chr6_-_26569321_265693720.721.8e-03Click!

Activity profile of sox14 motif

Sorted Z-values of sox14 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of sox14

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_12733209 2.74 ENSDART00000167021
mcm6
minichromosome maintenance complex component 6
chr11_-_29910947 2.35 ENSDART00000156121
scml2
sex comb on midleg-like 2 (Drosophila)
chr7_+_25642061 2.20 ENSDART00000135728
hmgb3a
high mobility group box 3a
chr1_+_25662652 2.10 ENSDART00000113020
tet2
tet methylcytosine dioxygenase 2
chr16_+_26989962 2.09 ENSDART00000140673
galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr14_+_11151485 2.07 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr14_+_47326080 2.05 ENSDART00000047525
cryba1l1
crystallin, beta A1, like 1
chr9_-_42894582 2.04 ENSDART00000144744
col5a2a
collagen, type V, alpha 2a
chr13_-_13163676 1.92 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
chr10_+_18994733 1.92 ENSDART00000146517
dpysl2b
dihydropyrimidinase-like 2b
chr25_+_34069931 1.87

chr19_-_7531709 1.79 ENSDART00000104750
mllt11
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11
chr23_+_36832325 1.76

chr23_+_37754409 1.74

chr11_+_15478585 1.73 ENSDART00000163289
ENSDART00000066033
gdf11
growth differentiation factor 11
chr7_+_25641990 1.68 ENSDART00000129924
hmgb3a
high mobility group box 3a
chr6_+_7309023 1.67 ENSDART00000160128
erbb3a
erb-b2 receptor tyrosine kinase 3a
chr14_-_32449229 1.60 ENSDART00000172996
AL590151.1
ENSDARG00000053570
chr10_+_33227967 1.60 ENSDART00000159666
myl10
myosin, light chain 10, regulatory
chr6_-_39767452 1.52 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr10_+_4962403 1.52 ENSDART00000134679
CU074419.2
ENSDARG00000093688
chr9_-_11589126 1.51 ENSDART00000146832
cryba2b
crystallin, beta A2b
chr6_+_30681170 1.48 ENSDART00000112294
ttc22
tetratricopeptide repeat domain 22
chr4_-_76620869 1.46

chr23_-_19789409 1.43 ENSDART00000131860
rpl10
ribosomal protein L10
chr10_-_27261937 1.43

chr23_-_6707246 1.42 ENSDART00000023793
mipb
major intrinsic protein of lens fiber b
chr1_+_25662910 1.35 ENSDART00000113020
tet2
tet methylcytosine dioxygenase 2
chr16_+_14697969 1.29 ENSDART00000133566
deptor
DEP domain containing MTOR-interacting protein
chr9_+_1177938 1.28 ENSDART00000176589
CABZ01066921.1
ENSDARG00000106418
chr2_-_56224858 1.28 ENSDART00000060745
uba52
ubiquitin A-52 residue ribosomal protein fusion product 1
chr13_-_31339870 1.25 ENSDART00000076574
rtn1a
reticulon 1a
chr8_-_13503775 1.24 ENSDART00000063834
ENSDARG00000043482
ENSDARG00000043482
chr12_-_28840796 1.24

chr13_-_13163801 1.24 ENSDART00000156968
fgfr3
fibroblast growth factor receptor 3
chr21_+_20734431 1.21 ENSDART00000079732
oxct1b
3-oxoacid CoA transferase 1b
chr7_-_38590391 1.20 ENSDART00000037361
ENSDART00000173629
ENSDART00000173953
phf21aa
PHD finger protein 21Aa
chr4_-_72097569 1.19 ENSDART00000108669
zgc:171551
zgc:171551
chr8_-_22945616 1.19

chr10_+_5413893 1.18 ENSDART00000138821
nfil3
nuclear factor, interleukin 3 regulated
chr21_+_25651712 1.18 ENSDART00000135123
si:dkey-17e16.17
si:dkey-17e16.17
chr21_-_35806638 1.17 ENSDART00000172245
sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr10_-_11806373 1.16 ENSDART00000009715
adamts6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr4_+_28860191 1.16 ENSDART00000110358
ENSDART00000162069
znf1059
zinc finger protein 1059
chr3_-_38642067 1.12 ENSDART00000155518
znf281a
zinc finger protein 281a
chr6_+_33556031 1.11 ENSDART00000147625
pik3r3b
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr23_+_36032206 1.11 ENSDART00000103132
hoxc4a
homeobox C4a
chr8_-_49183600 1.11 ENSDART00000134269
fkbp1aa
FK506 binding protein 1Aa
chr12_+_29931452 1.10 ENSDART00000153394
ablim1b
actin binding LIM protein 1b
chr19_-_19290260 1.09

chr2_+_56339323 1.09 ENSDART00000123392
rab11bb
RAB11B, member RAS oncogene family, b
chr13_-_31304614 1.07

chr25_-_28691412 1.05 ENSDART00000067066
parp6b
poly (ADP-ribose) polymerase family, member 6b
chr14_-_25301744 1.04 ENSDART00000131886
slc25a48
solute carrier family 25, member 48
chr21_+_43674754 1.03 ENSDART00000136025
tmlhe
trimethyllysine hydroxylase, epsilon
chr18_-_13234871 1.00 ENSDART00000142942
klhl36
kelch-like family member 36
chr9_-_306569 0.99 ENSDART00000166059
si:ch211-166e11.5
si:ch211-166e11.5
chr9_-_23340795 0.97 ENSDART00000133017
lypd6b
LY6/PLAUR domain containing 6B
chr12_-_17357133 0.97 ENSDART00000079115
papss2b
3'-phosphoadenosine 5'-phosphosulfate synthase 2b
chr8_-_17031599 0.97 ENSDART00000132687
rab3c
RAB3C, member RAS oncogene family
chr19_+_47719438 0.96 ENSDART00000138295
ext1c
exostoses (multiple) 1c
chr9_+_1177862 0.94 ENSDART00000176589
CABZ01066921.1
ENSDARG00000106418
chr11_-_18393802 0.93 ENSDART00000125453
dido1
death inducer-obliterator 1
chr19_-_44043806 0.93 ENSDART00000138009
ENSDART00000086138
fam83hb
family with sequence similarity 83, member Hb
chr9_-_22371512 0.92 ENSDART00000101809
crygm2d6
crystallin, gamma M2d6
chr23_-_7892862 0.90 ENSDART00000157612
ENSDART00000165427
myt1b
myelin transcription factor 1b
chr7_-_57030751 0.89

chr12_+_22558928 0.88 ENSDART00000077548
ablim2
actin binding LIM protein family, member 2
chr25_-_36760720 0.87 ENSDART00000111862
ldlrad3
low density lipoprotein receptor class A domain containing 3
chr15_+_15479719 0.85 ENSDART00000127436
zgc:92630
zgc:92630
chr13_-_20387917 0.84 ENSDART00000167916
ENSDART00000165310
ENSDART00000168955
gfra1a
gdnf family receptor alpha 1a
chr15_-_33960811 0.82 ENSDART00000158325
n4bp2l2
NEDD4 binding protein 2-like 2
chr2_+_36957471 0.82 ENSDART00000143915
gadd45bb
growth arrest and DNA-damage-inducible, beta b
chr18_+_21133694 0.82 ENSDART00000060015
chka
choline kinase alpha
chr22_+_5657904 0.80 ENSDART00000138102
dnase1l4.2
deoxyribonuclease 1 like 4, tandem duplicate 2
chr1_-_32825184 0.79 ENSDART00000075632
creb1a
cAMP responsive element binding protein 1a
chr11_-_42626842 0.79 ENSDART00000052912
pcdh20
protocadherin 20
chr22_+_38837247 0.77 ENSDART00000144318
anos1b
anosmin 1b
chr18_+_37034218 0.75

chr19_-_44043682 0.75 ENSDART00000138009
ENSDART00000086138
fam83hb
family with sequence similarity 83, member Hb
chr15_+_657554 0.72 ENSDART00000156007
si:ch73-144d13.8
si:ch73-144d13.8
chr11_+_23694891 0.70 ENSDART00000000486
cntn2
contactin 2
chr19_-_41819752 0.69 ENSDART00000167772
shfm1
split hand/foot malformation (ectrodactyly) type 1
chr2_-_39052185 0.68 ENSDART00000048838
rbp2b
retinol binding protein 2b, cellular
chr17_-_5703094 0.68 ENSDART00000058894
si:ch73-340m8.2
si:ch73-340m8.2
chr3_+_52901602 0.67 ENSDART00000114343
brd4
bromodomain containing 4
chr6_+_33556155 0.66 ENSDART00000147625
pik3r3b
phosphoinositide-3-kinase, regulatory subunit 3b (gamma)
chr4_-_25807510 0.65 ENSDART00000122881
tmcc3
transmembrane and coiled-coil domain family 3
chr23_-_17078715 0.64 ENSDART00000080545
dnmt3bb.2
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate b.2
chr4_-_38406131 0.63

chr5_-_57016269 0.62 ENSDART00000074264
crfb12
cytokine receptor family member B12
chr18_+_45203251 0.61 ENSDART00000015786
gyltl1b
glycosyltransferase-like 1b
chr12_+_22455344 0.61 ENSDART00000172053
capgb
capping protein (actin filament), gelsolin-like b
chr6_-_37765778 0.61 ENSDART00000149068
nipa2
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr16_-_42157129 0.60

chr14_-_952510 0.59 ENSDART00000130801
acsl1b
acyl-CoA synthetase long-chain family member 1b
chr6_+_43429115 0.57 ENSDART00000056457
mitfa
microphthalmia-associated transcription factor a
chr21_-_21477423 0.57 ENSDART00000164076
pvrl3b
poliovirus receptor-related 3b
chr8_+_26502909 0.56 ENSDART00000046863
sema3bl
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3bl
chr23_-_3815492 0.56 ENSDART00000131536
hmga1a
high mobility group AT-hook 1a
chr19_-_7531649 0.56 ENSDART00000104750
mllt11
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11
chr16_+_26990064 0.56 ENSDART00000140673
galnt1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1
chr15_-_37832225 0.54 ENSDART00000059568
si:ch211-137j23.6
si:ch211-137j23.6
chr19_-_34328673 0.54 ENSDART00000164563
elmo1
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr21_-_2222412 0.53 ENSDART00000169448
si:ch73-299h12.1
si:ch73-299h12.1
chr5_+_296856 0.53

chr14_-_29565869 0.50 ENSDART00000172349
sorbs2b
sorbin and SH3 domain containing 2b
chr20_+_35479428 0.50 ENSDART00000159483
ENSDART00000031091
BX511024.1
vsnl1a
ENSDARG00000104812
visinin-like 1a
chr1_+_2074153 0.48 ENSDART00000058877
rap2ab
RAP2A, member of RAS oncogene family b
chr13_+_12651778 0.47 ENSDART00000090000
si:ch211-233a24.2
si:ch211-233a24.2
chr5_-_55745399 0.47

chr12_-_425381 0.46 ENSDART00000083827
hs3st3l
heparan sulfate (glucosamine) 3-O-sulfotransferase 3-like
chr20_+_49975268 0.46 ENSDART00000008808
hmbox1b
homeobox containing 1 b
chr20_+_53716378 0.46 ENSDART00000139794
pak6b
p21 protein (Cdc42/Rac)-activated kinase 6b
chr22_+_18762028 0.46 ENSDART00000105399
cbarpb
calcium channel, voltage-dependent, beta subunit associated regulatory protein b
chr20_+_54247734 0.45 ENSDART00000143172
wdr20b
WD repeat domain 20b
chr16_+_25158949 0.44 ENSDART00000155465
si:dkeyp-84f3.9
si:dkeyp-84f3.9
chr6_+_30469823 0.44 ENSDART00000121492
FP236735.1
ENSDARG00000087805
chr13_-_13163647 0.43 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
chr4_-_13394059 0.43 ENSDART00000175909
ENSDART00000174861
BX511038.1
ENSDARG00000108089
chr3_-_28534446 0.43 ENSDART00000151670
fbxl16
F-box and leucine-rich repeat protein 16
chr23_+_42920817 0.42 ENSDART00000055577
myl9a
myosin, light chain 9a, regulatory
chr25_-_22850980 0.42 ENSDART00000175228
CU462979.1
ENSDARG00000107627
chr17_-_37266525 0.42 ENSDART00000128715
kif3cb
kinesin family member 3Cb
chr11_-_18016658 0.41

chr9_-_13991784 0.41 ENSDART00000061156
raph1a
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr13_-_31340029 0.40 ENSDART00000076574
rtn1a
reticulon 1a
chr3_-_49104540 0.40 ENSDART00000138503
btr02
bloodthirsty-related gene family, member 2
chr25_-_34607624 0.40 ENSDART00000128017
CU302436.1
ENSDARG00000051726
chr2_-_26987186 0.40 ENSDART00000132854
u2surp
U2 snRNP-associated SURP domain containing
chr7_+_54347388 0.39 ENSDART00000158898
fgf4
fibroblast growth factor 4
chr11_+_13000957 0.38 ENSDART00000161532
zfyve9b
zinc finger, FYVE domain containing 9b
chr22_-_15666856 0.38 ENSDART00000141861
si:ch1073-396h14.1
si:ch1073-396h14.1
chr25_+_21735567 0.37 ENSDART00000148299
ckmt1
creatine kinase, mitochondrial 1
chr5_-_24208617 0.35 ENSDART00000033630
ENSDARG00000022772
ENSDARG00000022772
chr6_+_3356712 0.35 ENSDART00000151607
faah
fatty acid amide hydrolase
chr10_-_27262050 0.34

chr13_-_20388016 0.34 ENSDART00000167916
ENSDART00000165310
ENSDART00000168955
gfra1a
gdnf family receptor alpha 1a
chr14_+_29933552 0.34

chr1_-_32825274 0.34 ENSDART00000075632
creb1a
cAMP responsive element binding protein 1a
chr3_-_25144722 0.34 ENSDART00000055445
ddx5
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr8_-_23754376 0.32 ENSDART00000114800
INAVA
innate immunity activator
chr21_-_22694225 0.32 ENSDART00000101797
fbxo40.1
F-box protein 40, tandem duplicate 1
chr19_-_28382815 0.31 ENSDART00000110016
ube2ql1
ubiquitin-conjugating enzyme E2Q family-like 1
chr19_+_47719402 0.30 ENSDART00000138295
ext1c
exostoses (multiple) 1c
chr10_-_175160 0.30

chr10_-_9294185 0.30

chr4_-_22509152 0.29 ENSDART00000176950
ppfia2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr14_+_23419894 0.29 ENSDART00000006373
ndfip1
Nedd4 family interacting protein 1
chr23_-_27930478 0.29 ENSDART00000043462
acvrl1
activin A receptor type II-like 1
chr12_+_2958777 0.29 ENSDART00000082297
lrrc45
leucine rich repeat containing 45
chr13_+_5442296 0.28 ENSDART00000134506
si:dkey-196j8.2
si:dkey-196j8.2
chr11_+_11284217 0.28 ENSDART00000026814
ptp4a1
protein tyrosine phosphatase type IVA, member 1
chr12_-_2766066 0.27 ENSDART00000152682
ubtd1b
ubiquitin domain containing 1b
chr16_-_45450439 0.27

chr20_-_21775455 0.27

chr17_+_33862300 0.27

chr16_+_54350976 0.27 ENSDART00000172622
ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr21_+_37751640 0.26 ENSDART00000076328
pgrmc1
progesterone receptor membrane component 1
chr12_-_27497159 0.25 ENSDART00000066282
dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr14_-_2268924 0.24 ENSDART00000160205
pcdh2ab12
protocadherin 2 alpha b 12
chr16_-_25793780 0.23

chr10_-_27262098 0.22

chr4_-_47142181 0.21 ENSDART00000150426
znf1064
zinc finger protein 1064
chr23_-_12305794 0.20

chr7_+_28782951 0.19

chr12_-_16035939 0.18 ENSDART00000090881
si:dkey-100n10.2
si:dkey-100n10.2
chr19_+_46631965 0.18 ENSDART00000158703
vps28
vacuolar protein sorting 28 (yeast)
chr10_-_14604287 0.18

chr25_+_3551924 0.17 ENSDART00000154348
prnprs3
prion protein, related sequence 3
chr17_+_8768744 0.17

chr19_-_44044039 0.17 ENSDART00000138009
ENSDART00000086138
fam83hb
family with sequence similarity 83, member Hb
chr7_-_38590218 0.17 ENSDART00000133491
phf21aa
PHD finger protein 21Aa
chr1_-_499082 0.16 ENSDART00000144406
ENSDART00000031635
ercc5
excision repair cross-complementation group 5
chr8_+_18800414 0.16 ENSDART00000160732
mpnd
MPN domain containing
chr2_-_56265681 0.16 ENSDART00000036240
cers4b
ceramide synthase 4b
chr5_+_38143180 0.15 ENSDART00000137658
si:dkey-58f10.6
si:dkey-58f10.6
chr19_+_42768795 0.14

chr18_+_15872911 0.14 ENSDART00000141800
eea1
early endosome antigen 1
chr5_-_21430034 0.14

chr18_+_37279031 0.13 ENSDART00000135444
tbcb
tubulin folding cofactor B
chr19_-_15324958 0.13 ENSDART00000055619
phactr4a
phosphatase and actin regulator 4a
chr18_+_14509074 0.13 ENSDART00000146472
kcng4a
potassium voltage-gated channel, subfamily G, member 4a
chr5_+_38904048 0.12 ENSDART00000121460
prdm8b
PR domain containing 8b
chr13_-_49430733 0.11

chr6_-_39767422 0.11 ENSDART00000085277
pfkmb
phosphofructokinase, muscle b
chr19_+_13492428 0.10 ENSDART00000165033
srsf4
serine/arginine-rich splicing factor 4
chr3_+_41573049 0.09 ENSDART00000155440
eif3ba
eukaryotic translation initiation factor 3, subunit Ba
chr7_+_55217611 0.09 ENSDART00000149915
cdt1
chromatin licensing and DNA replication factor 1
chr8_-_45752084 0.08 ENSDART00000025620
ppiaa
peptidylprolyl isomerase Aa (cyclophilin A)
chr2_-_37151666 0.08 ENSDART00000146123
elavl1
ELAV like RNA binding protein 1
chr23_-_27930393 0.08 ENSDART00000043462
acvrl1
activin A receptor type II-like 1
chr20_+_34019004 0.08 ENSDART00000161363
lmx1a
LIM homeobox transcription factor 1, alpha
chr1_+_53353287 0.07 ENSDART00000012104
dla
deltaA
chr24_-_31257591 0.07 ENSDART00000158808
cnn3a
calponin 3, acidic a
chr13_+_23767450 0.07 ENSDART00000002244
sf3b5
splicing factor 3b, subunit 5
chr6_+_9801649 0.06 ENSDART00000149537
sucla2
succinate-CoA ligase, ADP-forming, beta subunit
chr5_+_38143502 0.05 ENSDART00000137658
si:dkey-58f10.6
si:dkey-58f10.6
chr2_+_37992682 0.05 ENSDART00000179233
CR376839.1
ENSDARG00000108815
chr15_-_723851 0.05

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0006211 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
0.5 2.3 GO:0090199 regulation of mitochondrial membrane potential(GO:0051881) membrane depolarization(GO:0051899) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.3 1.2 GO:0046950 cellular ketone body metabolic process(GO:0046950) ketone body metabolic process(GO:1902224)
0.2 1.6 GO:0006007 glucose catabolic process(GO:0006007) NADH regeneration(GO:0006735) glycolytic process through fructose-6-phosphate(GO:0061615) glycolytic process through glucose-6-phosphate(GO:0061620) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 2.7 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) mitotic DNA replication(GO:1902969)
0.2 0.9 GO:0003322 pancreatic A cell development(GO:0003322)
0.2 1.4 GO:0006833 water transport(GO:0006833)
0.2 0.7 GO:0048682 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.2 1.9 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
0.2 1.0 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 0.7 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.2 1.0 GO:0034036 sulfate assimilation(GO:0000103) purine ribonucleoside bisphosphate metabolic process(GO:0034035) purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 0.5 GO:0051701 interaction with host(GO:0051701)
0.1 0.3 GO:1903429 regulation of cell maturation(GO:1903429)
0.1 0.5 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 1.8 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.1 0.9 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.1 3.6 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.8 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.6 GO:0051570 regulation of histone H3-K9 methylation(GO:0051570)
0.1 0.5 GO:0045955 negative regulation of calcium ion-dependent exocytosis(GO:0045955) negative regulation of regulated secretory pathway(GO:1903306)
0.1 1.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.2 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.1 4.5 GO:0007601 visual perception(GO:0007601)
0.1 0.4 GO:0034405 response to fluid shear stress(GO:0034405)
0.1 1.0 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 1.0 GO:0051181 cofactor transport(GO:0051181)
0.1 0.8 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.7 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.4 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.0 0.3 GO:0000012 single strand break repair(GO:0000012)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.8 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 1.3 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.9 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 1.1 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 1.0 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.6 GO:0051014 actin filament severing(GO:0051014)
0.0 0.5 GO:0002429 immune response-activating cell surface receptor signaling pathway(GO:0002429)
0.0 0.1 GO:0055016 hypochord development(GO:0055016)
0.0 1.8 GO:0007623 circadian rhythm(GO:0007623)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.5 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.0 3.1 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.9 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.0 0.6 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.0 0.4 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.9 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.6 GO:0007599 blood coagulation(GO:0007596) hemostasis(GO:0007599)
0.0 0.2 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 2.6 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.4 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.6 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 1.1 GO:0045055 regulated exocytosis(GO:0045055)
0.0 0.1 GO:0003313 heart rudiment development(GO:0003313)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 1.6 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.2 1.7 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 2.7 GO:0042555 MCM complex(GO:0042555)
0.1 0.4 GO:0070724 BMP receptor complex(GO:0070724)
0.1 0.9 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.1 1.7 GO:0045095 keratin filament(GO:0045095)
0.1 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.8 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 1.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.3 GO:0022626 cytosolic ribosome(GO:0022626)
0.0 1.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.0 1.6 GO:0055037 recycling endosome(GO:0055037)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.7 2.7 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.3 1.0 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.3 1.3 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.3 1.2 GO:0008410 CoA-transferase activity(GO:0008410)
0.3 1.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.2 1.4 GO:0015250 water channel activity(GO:0015250)
0.2 1.6 GO:0003872 6-phosphofructokinase activity(GO:0003872) fructose-6-phosphate binding(GO:0070095)
0.2 3.9 GO:0008301 DNA binding, bending(GO:0008301)
0.2 3.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 1.0 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.2 4.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.8 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.1 1.0 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.1 0.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 1.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.3 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.1 0.7 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.3 GO:0031386 protein tag(GO:0031386)
0.1 0.6 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 1.8 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.4 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.0 0.9 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.4 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.6 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 2.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.7 GO:0019838 growth factor binding(GO:0019838)
0.0 1.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 1.0 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.1 GO:0004775 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.0 2.6 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.7 GO:0005125 cytokine activity(GO:0005125)
0.0 1.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0044325 ion channel binding(GO:0044325)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.5 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0070122 isopeptidase activity(GO:0070122)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 PID FGF PATHWAY FGF signaling pathway
0.0 0.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.3 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.3 1.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 2.7 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.6 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.5 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 1.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis