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Results for sox17

Z-value: 0.59

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Transcription factors associated with sox17

Gene Symbol Gene ID Gene Info
ENSDARG00000101717 SRY-box transcription factor 17

Activity profile of sox17 motif

Sorted Z-values of sox17 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of sox17

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr18_+_20571619 2.33 ENSDART00000040074
WEE1 homolog 2 (S. pombe)
chr23_+_32174669 1.33 ENSDART00000000992
ENSDARG00000000887
chr22_-_20236308 1.23

chr5_-_23211957 1.18 ENSDART00000019992
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 1
chr12_-_3042394 1.12 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr5_-_32433490 1.08

chr24_-_9880951 1.06 ENSDART00000137250
zgc:173856
chr14_+_29932533 1.05 ENSDART00000017122
N-acylsphingosine amidohydrolase (acid ceramidase) 1a
chr21_+_3627192 1.03 ENSDART00000139813
torsin family 1
chr5_-_49417365 1.00

chr22_+_1837102 0.99 ENSDART00000163288
zinc finger protein 1174
chr21_-_32747592 0.97

chr24_+_9887575 0.96 ENSDART00000172773
si:ch211-146l10.8
chr13_+_11418060 0.95 ENSDART00000166908
desumoylating isopeptidase 2
chr18_+_17545564 0.94 ENSDART00000061007
metallothionein 2
chr7_+_66660882 0.91 ENSDART00000082664
SET binding factor 2
chr19_+_33360759 0.89 ENSDART00000052091
ATPase, H+ transporting, lysosomal, V1 subunit C1b
chr7_+_38078338 0.86 ENSDART00000010046
rhophilin, Rho GTPase binding protein 2
chr22_+_30041252 0.78 ENSDART00000165313
si:dkey-286j15.3
chr18_-_958923 0.78

chr23_+_19728953 0.78 ENSDART00000104441
abhydrolase domain containing 6b
chr17_-_16414577 0.78 ENSDART00000150149
tyrosyl-DNA phosphodiesterase 1
chr2_-_26941084 0.76 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr3_+_13034056 0.76

KN150339v1_-_39357 0.74 ENSDART00000169638
wu:fa19b12
chr3_+_18287783 0.73 ENSDART00000144690
TBC1 domain family, member 16
chr13_+_11417882 0.70 ENSDART00000034935
desumoylating isopeptidase 2
chr5_-_32433573 0.69

chr8_-_44617367 0.68 ENSDART00000063396
BCL2-associated athanogene 4
chr2_-_26941232 0.68 ENSDART00000134685
ENSDART00000056787
zgc:113691
chr10_-_45182378 0.68 ENSDART00000161815
polymerase (DNA directed), mu
chr13_-_402878 0.68 ENSDART00000038315
nuclear VCP-like
chr23_+_30803518 0.68 ENSDART00000134141
additional sex combs like transcriptional regulator 1
chr1_+_8468971 0.68 ENSDART00000081343
polo-like kinase 1 (Drosophila)
chr3_+_18287645 0.68 ENSDART00000136243
TBC1 domain family, member 16
chr10_+_19625897 0.67

chr16_+_25192196 0.66 ENSDART00000033211
zgc:66448
chr1_-_45958767 0.66 ENSDART00000053222
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr13_+_50990946 0.65

chr2_+_223139 0.65 ENSDART00000113021
DEAH (Asp-Glu-Ala-His) box helicase 30
chr20_-_21033044 0.65 ENSDART00000152415
BTB (POZ) domain containing 6b
chr18_+_20571460 0.64 ENSDART00000151990
WEE1 homolog 2 (S. pombe)
chr21_-_37750338 0.63 ENSDART00000133585
family with sequence similarity 114, member A2
chr21_+_11943637 0.63 ENSDART00000141306
zgc:162344
chr14_+_15788442 0.62 ENSDART00000159181
inner membrane protein, mitochondrial (mitofilin)
chr7_+_10319999 0.61 ENSDART00000168801
zinc finger, AN1-type domain 6
chr1_+_52686620 0.61 ENSDART00000176087
TBC1 domain family, member 9 (with GRAM domain)
chr19_-_43434166 0.61

chr12_+_35855929 0.61

chr1_+_52686770 0.60 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr9_-_21287478 0.60 ENSDART00000018570
tryptophanyl tRNA synthetase 2, mitochondrial
KN149908v1_+_8072 0.60

chr12_-_30244042 0.59 ENSDART00000152878
tudor domain containing 1
chr2_+_38042821 0.58 ENSDART00000134211
ENSDART00000144868
heterogeneous nuclear ribonucleoprotein C
chr18_+_35253031 0.58

chr13_-_33186642 0.57 ENSDART00000110295
transmembrane protein 234
chr24_+_12691540 0.57

chr21_+_3627046 0.57 ENSDART00000139813
torsin family 1
chr22_+_1335355 0.57 ENSDART00000169629
zinc finger 45 like
chr12_-_926596 0.56 ENSDART00000088351
sperm associated antigen 9
chr8_-_44617324 0.55 ENSDART00000063396
BCL2-associated athanogene 4
chr12_-_30244575 0.55 ENSDART00000152981
tudor domain containing 1
chr5_+_51186708 0.55 ENSDART00000165276
PAP associated domain containing 4
chr16_-_55211053 0.55 ENSDART00000156533
keratinocyte differentiation factor 1a
chr24_-_16835352 0.55 ENSDART00000005331
ENSDART00000128446
kelch-like family member 15
chr15_-_18273640 0.54 ENSDART00000141508
bloodthirsty-related gene family, member 16
chr23_+_32175042 0.54 ENSDART00000138849
ENSDARG00000000887
chr19_-_17306473 0.54 ENSDART00000007906
stathmin 1a
chr22_-_9790536 0.54

chr12_-_49212400 0.52 ENSDART00000112479
acyl-CoA dehydrogenase, short/branched chain
chr12_-_33256599 0.52 ENSDART00000066233
ENSDART00000148165
solute carrier family 16 (monocarboxylate transporter), member 3
chr22_+_32274436 0.51 ENSDART00000092082
mesencephalic astrocyte-derived neurotrophic factor
chr5_+_38498787 0.51 ENSDART00000006079
BMP2 inducible kinase
chr20_-_46079578 0.50 ENSDART00000153228
ENSDARG00000096676
chr8_-_44617200 0.50 ENSDART00000063396
BCL2-associated athanogene 4
chr7_+_10320142 0.49 ENSDART00000168801
zinc finger, AN1-type domain 6
chr5_+_36904127 0.49 ENSDART00000165465
si:ch1073-224n8.1
chr3_+_28729443 0.48 ENSDART00000077235
ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr5_+_35930704 0.48 ENSDART00000006899
immunoglobulin (CD79A) binding protein 1
chr23_-_24615681 0.48 ENSDART00000132265
ATPase type 13A2
chr15_+_6462943 0.48 ENSDART00000065824
beta-site APP-cleaving enzyme 2
chr11_-_27290434 0.48 ENSDART00000173444
protein tyrosine phosphatase domain containing 1a
chr25_-_13394261 0.48 ENSDART00000056721
lactate dehydrogenase D
chr16_+_35952050 0.48 ENSDART00000162411
SH3 domain containing 21
chr18_+_20571513 0.47 ENSDART00000136710
WEE1 homolog 2 (S. pombe)
chr20_-_49067167 0.47 ENSDART00000163071
ENSDART00000170617
5'-3' exoribonuclease 2
chr13_-_4535689 0.47 ENSDART00000023803
C1D nuclear receptor corepressor
chr15_-_31104074 0.46 ENSDART00000157005
neurofibromin 1a
chr2_+_22753634 0.46 ENSDART00000171853
zgc:56628
chr13_-_31557441 0.45 ENSDART00000085989
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
chr25_+_20596490 0.45 ENSDART00000073648
KxDL motif containing 1
chr18_-_46185361 0.45 ENSDART00000021192
potassium channel, subfamily K, member 6
chr24_-_10935904 0.45 ENSDART00000003195
charged multivesicular body protein 4C
chr11_+_25302044 0.45 ENSDART00000035602
CXXC finger protein 1b
chr20_+_40560443 0.45 ENSDART00000153119
serine incorporator 1
chr16_+_41767185 0.44 ENSDART00000015170
metadherin b
chr23_+_30803887 0.44 ENSDART00000134141
additional sex combs like transcriptional regulator 1
chr4_+_13413303 0.44 ENSDART00000003694
cullin-associated and neddylation-dissociated 1
chr13_+_11307037 0.44 ENSDART00000138312
zinc finger and BTB domain containing 18
chr5_+_51186666 0.44 ENSDART00000165276
PAP associated domain containing 4
chr1_-_51863300 0.44 ENSDART00000004233
aspartoacylase (aminocyclase) 3, tandem duplicate 2
chr2_+_38042740 0.43 ENSDART00000134211
ENSDART00000144868
heterogeneous nuclear ribonucleoprotein C
chr23_+_28464642 0.43 ENSDART00000133736
ENSDARG00000093306
chr14_+_26268810 0.43 ENSDART00000173056
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr21_+_11943609 0.43 ENSDART00000155426
ENSDART00000102463
zgc:162344
chr17_-_11904068 0.43 ENSDART00000105236
SET and MYND domain containing 3
chr12_-_3042573 0.43 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr23_+_16848278 0.42 ENSDART00000104791
zgc:153722
chr20_-_46079529 0.42 ENSDART00000153228
ENSDARG00000096676
chr6_-_8156471 0.42 ENSDART00000081561
interleukin enhancer binding factor 3a
chr11_-_33605979 0.42 ENSDART00000171439
si:ch211-227n13.3
chr3_+_34690574 0.41

chr24_-_24884787 0.41 ENSDART00000168254
nucleoporin 58
chr4_-_3215313 0.41 ENSDART00000112210
pleckstrin homology domain containing, family A member 5
chr7_-_39107780 0.41 ENSDART00000173659
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr17_-_19943767 0.41 ENSDART00000154251
cholinergic receptor, muscarinic 3a
chr1_+_57891538 0.41 ENSDART00000158425
ENSDARG00000105176
chr11_+_25302180 0.41 ENSDART00000035602
CXXC finger protein 1b
chr6_-_29386437 0.41 ENSDART00000168905
transmembrane protein 131
chr7_-_13555920 0.40 ENSDART00000172852
si:cabz01068815.1
chr13_+_31557497 0.40 ENSDART00000076479
solute carrier family 38, member 6
chr21_+_7570420 0.40 ENSDART00000161921
zgc:113019
chr13_-_30938624 0.40 ENSDART00000112653
WDFY family member 4
chr9_-_46475965 0.40 ENSDART00000165238
histone deacetylase 4
chr19_+_43316957 0.39 ENSDART00000151298
cAMP-regulated phosphoprotein, 21
chr25_+_20596613 0.39 ENSDART00000073648
KxDL motif containing 1
chr16_-_28723759 0.39 ENSDART00000148456
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr12_-_16403282 0.38 ENSDART00000037601
ribonuclease P/MRP 30 subunit
chr15_-_31103957 0.38 ENSDART00000080328
neurofibromin 1a
chr12_-_3042545 0.38 ENSDART00000002867
ENSDART00000126315
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_+_57878303 0.38 ENSDART00000162460
si:ch73-221f6.3
chr18_-_44365869 0.37 ENSDART00000166935
PR domain containing 10
chr16_-_47366405 0.37 ENSDART00000169697
missing oocyte, meiosis regulator, homolog (Drosophila)
chr18_-_21736549 0.37 ENSDART00000089853
FANCD2/FANCI-associated nuclease 1
chr17_-_20198477 0.37 ENSDART00000063523
O-6-methylguanine-DNA methyltransferase
chr16_+_28829383 0.37 ENSDART00000122433
tripartite motif containing 33, like
chr9_+_38648006 0.37 ENSDART00000142512
minichromosome maintenance complex component 3 associated protein
chr10_-_6587281 0.36 ENSDART00000163788
ENSDART00000171833
chromodomain helicase DNA binding protein 1
chr2_+_52225622 0.36 ENSDART00000170353
ENSDARG00000103108
chr10_+_39971944 0.36 ENSDART00000003435
small fragment nuclease
chr23_+_25047201 0.36 ENSDART00000047020
caspase 9, apoptosis-related cysteine peptidase
chr17_+_11921705 0.36 ENSDART00000155329
consortin, connexin sorting protein a
chr11_-_30388949 0.36 ENSDART00000063775
ENSDARG00000043442
chr13_+_11306913 0.36 ENSDART00000138312
zinc finger and BTB domain containing 18
chr5_-_53776769 0.36 ENSDART00000164595
coenzyme Q4 homolog (S. cerevisiae)
chr14_-_46477165 0.36 ENSDART00000173209
ENSDART00000164837
EH-domain containing 1a
chr3_+_34876160 0.35 ENSDART00000029451
protein kinase C, beta b
chr20_+_19045423 0.34 ENSDART00000035447
myotubularin related protein 9
chr24_+_12693997 0.34

chr2_-_17820860 0.34 ENSDART00000024302
lysine (K)-specific demethylase 4A, genome duplicate b
chr21_-_16442202 0.34

chr10_-_6587375 0.34 ENSDART00000163788
ENSDART00000171833
chromodomain helicase DNA binding protein 1
chr24_-_24884729 0.34 ENSDART00000168254
nucleoporin 58
chr8_-_53593850 0.33

chr4_-_12782246 0.33 ENSDART00000058020
helicase (DNA) B
chr8_-_2471264 0.33 ENSDART00000056767
acetyl-CoA acyltransferase 2
chr13_+_11306998 0.33 ENSDART00000138312
zinc finger and BTB domain containing 18
chr11_+_25302072 0.33 ENSDART00000035602
CXXC finger protein 1b
chr21_-_32748287 0.32 ENSDART00000031028
CCR4-NOT transcription complex, subunit 6a
chr10_+_36718872 0.32 ENSDART00000063359
uncoupling protein 3
chr19_-_17306333 0.31 ENSDART00000132662
stathmin 1a
chr7_+_23224924 0.31 ENSDART00000142401
zgc:109889
chr19_-_2314696 0.30 ENSDART00000166669
biotinidase
chr23_+_16848213 0.30 ENSDART00000104791
zgc:153722
chr22_-_9790451 0.30

chr5_-_22364806 0.30 ENSDART00000057541
apolipoprotein O-like
chr19_+_33360835 0.30 ENSDART00000052091
ATPase, H+ transporting, lysosomal, V1 subunit C1b
chr13_-_9034919 0.30 ENSDART00000135373
si:dkey-33c12.4
chr22_+_1965847 0.30

chr24_-_16835253 0.30 ENSDART00000005331
ENSDART00000128446
kelch-like family member 15
chr18_+_7584201 0.30 ENSDART00000163709
zgc:77650
chr11_+_11050173 0.29

chr4_+_18427325 0.29

chr16_+_38251653 0.29 ENSDART00000044971
myosin IE, b
chr3_+_34690515 0.29

chr18_-_44366076 0.29 ENSDART00000166935
PR domain containing 10
chr18_+_20571785 0.29 ENSDART00000040074
WEE1 homolog 2 (S. pombe)
chr21_-_32747544 0.28

chr19_+_42863138 0.28 ENSDART00000076938
pogo transposable element derived with ZNF domain a
chr1_+_52686829 0.28 ENSDART00000143909
TBC1 domain family, member 9 (with GRAM domain)
chr24_+_26918580 0.28 ENSDART00000161327
La ribonucleoprotein domain family, member 4B
chr19_-_35380449 0.28

chr2_-_21954556 0.27 ENSDART00000145040
v-ral simian leukemia viral oncogene homolog Ab (ras related)
chr3_-_39048361 0.27 ENSDART00000013167
retinol saturase (all-trans-retinol 13,14-reductase)
chr14_+_11836698 0.27 ENSDART00000012438
heat shock protein 9
chr19_-_44469947 0.27 ENSDART00000006338
mitochondrial transcription termination factor 3
chr6_-_37534996 0.27 ENSDART00000147826
jade family PHD finger 3
KN150699v1_-_7850 0.26

chr17_+_12878081 0.26 ENSDART00000115208
F-box protein 33
chr2_+_22753590 0.26 ENSDART00000171853
zgc:56628
chr2_-_26949759 0.26

chr18_-_44366105 0.26 ENSDART00000166935
PR domain containing 10
chr10_+_187740 0.26 ENSDART00000167367
v-ets avian erythroblastosis virus E26 oncogene homolog 2
chr7_+_23224800 0.25 ENSDART00000115299
ENSDART00000101423
zgc:109889
chr19_-_42988039 0.25 ENSDART00000128278
si:dkey-267n13.1
chr22_+_2386743 0.25 ENSDART00000132925
zgc:112977
chr23_-_15280634 0.25 ENSDART00000056570
PHD finger protein 20, b
chr17_+_18012036 0.24 ENSDART00000022758
SET domain containing 3
chr23_-_27515964 0.24 ENSDART00000167838
disco-interacting protein 2 homolog Ba
chr16_+_38251717 0.23 ENSDART00000044971
myosin IE, b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.7 GO:0060631 regulation of meiosis I(GO:0060631)
0.5 1.6 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 1.9 GO:0035283 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.2 0.6 GO:0006940 regulation of smooth muscle contraction(GO:0006940) vascular smooth muscle contraction(GO:0014829) positive regulation of muscle contraction(GO:0045933)
0.2 1.0 GO:0000012 single strand break repair(GO:0000012)
0.1 0.7 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 0.5 GO:0003334 keratinocyte development(GO:0003334) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 1.1 GO:0060251 regulation of glial cell proliferation(GO:0060251)
0.1 0.9 GO:0043536 positive regulation of blood vessel endothelial cell migration(GO:0043536) positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.4 GO:0010265 SCF complex assembly(GO:0010265)
0.1 1.2 GO:0030259 lipid glycosylation(GO:0030259)
0.1 1.1 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.5 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.7 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.1 1.2 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.1 0.5 GO:0021588 cerebellum formation(GO:0021588)
0.1 0.4 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 0.3 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.1 0.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.2 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.3 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.2 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.1 0.2 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.1 0.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.6 GO:0097324 beta-amyloid metabolic process(GO:0050435) melanocyte migration(GO:0097324)
0.1 0.4 GO:0006868 glutamine transport(GO:0006868)
0.1 0.2 GO:0072003 kidney rudiment formation(GO:0072003) pronephros formation(GO:0072116)
0.1 1.1 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.1 0.3 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.6 GO:2000601 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 1.5 GO:0097205 renal filtration(GO:0097205)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.7 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.7 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 0.2 GO:0042373 vitamin K metabolic process(GO:0042373) cellular response to fluid shear stress(GO:0071498)
0.0 0.4 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 0.6 GO:0000959 mitochondrial RNA metabolic process(GO:0000959)
0.0 1.5 GO:0050821 protein stabilization(GO:0050821)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 2.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.6 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.7 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.4 GO:0033683 nucleotide-excision repair, DNA incision(GO:0033683)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 0.1 GO:0046755 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.0 0.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.3 GO:0009409 response to cold(GO:0009409)
0.0 0.3 GO:0042026 protein refolding(GO:0042026)
0.0 0.2 GO:1901985 positive regulation of protein acetylation(GO:1901985) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0 0.4 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.3 GO:0010507 negative regulation of autophagy(GO:0010507)
0.0 0.1 GO:0010525 regulation of transposition, RNA-mediated(GO:0010525) negative regulation of transposition, RNA-mediated(GO:0010526) transposition, RNA-mediated(GO:0032197) positive regulation of neuron apoptotic process(GO:0043525) positive regulation of neuron death(GO:1901216)
0.0 0.1 GO:0097354 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.7 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.9 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.5 GO:0009636 response to toxic substance(GO:0009636)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.0 0.2 GO:0036302 atrioventricular canal development(GO:0036302)
0.0 0.4 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone metabolic process(GO:1901661) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.4 GO:0051607 defense response to virus(GO:0051607)
0.0 1.6 GO:0060027 convergent extension involved in gastrulation(GO:0060027)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.3 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.3 GO:0030537 larval locomotory behavior(GO:0008345) larval behavior(GO:0030537)
0.0 0.4 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.5 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 0.4 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.2 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0 0.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.9 GO:0051169 nucleocytoplasmic transport(GO:0006913) nuclear transport(GO:0051169)
0.0 0.5 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.1 GO:0045003 double-strand break repair via synthesis-dependent strand annealing(GO:0045003)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.2 1.1 GO:0035517 PR-DUB complex(GO:0035517)
0.2 1.1 GO:0071546 pi-body(GO:0071546)
0.1 0.4 GO:0070390 transcription export complex 2(GO:0070390)
0.1 0.5 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 0.2 GO:0070985 TFIIK complex(GO:0070985)
0.0 1.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.7 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.5 GO:0061617 MICOS complex(GO:0061617)
0.0 1.6 GO:0030426 growth cone(GO:0030426)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 2.1 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 0.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.5 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.5 GO:0005902 microvillus(GO:0005902)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.7 GO:0030496 midbody(GO:0030496)
0.0 0.0 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.2 GO:0043204 perikaryon(GO:0043204)
0.0 1.4 GO:0005769 early endosome(GO:0005769)
0.0 0.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0030175 filopodium(GO:0030175)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.9 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 1.1 GO:0034584 piRNA binding(GO:0034584)
0.3 1.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.3 1.0 GO:0017064 fatty acid amide hydrolase activity(GO:0017064)
0.2 1.0 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.1 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.6 GO:0099528 G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.1 0.4 GO:0004457 lactate dehydrogenase activity(GO:0004457)
0.1 1.7 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.4 GO:0070336 flap-structured DNA binding(GO:0070336)
0.1 1.6 GO:0019894 kinesin binding(GO:0019894)
0.1 0.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.4 GO:0004046 aminoacylase activity(GO:0004046)
0.1 0.5 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 3.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.5 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) efflux transmembrane transporter activity(GO:0015562)
0.1 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.6 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.5 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.4 GO:0035173 histone kinase activity(GO:0035173)
0.1 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 1.2 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0022841 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 0.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.4 GO:0097200 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.5 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 1.1 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.3 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) single-stranded DNA-dependent ATPase activity(GO:0043142)
0.0 0.6 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.4 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0015616 DNA translocase activity(GO:0015616)
0.0 1.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 1.0 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.0 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.3 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.4 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.1 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 3.1 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.7 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 0.1 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.7 GO:0003724 RNA helicase activity(GO:0003724)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.7 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 1.0 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)