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DANIO-CODE

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Results for sox19a+sox19b+sox3

Z-value: 2.92

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Transcription factors associated with sox19a+sox19b+sox3

Gene Symbol Gene ID Gene Info
sox19a
ENSDARG00000010770 SRY-box transcription factor 19a
sox19b
ENSDARG00000040266 SRY-box transcription factor 19b
sox3
ENSDARG00000053569 SRY-box transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox19bdr10_dc_chr7_-_26226451_26226578-0.971.2e-09Click!
sox19adr10_dc_chr5_-_23697487_236978170.802.3e-04Click!
sox3dr10_dc_chr14_-_32404076_324041770.757.5e-04Click!

Activity profile of sox19a+sox19b+sox3 motif

Sorted Z-values of sox19a+sox19b+sox3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of sox19a+sox19b+sox3

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_12733209 8.94 ENSDART00000167021
mcm6
minichromosome maintenance complex component 6
chr10_+_33227967 8.37 ENSDART00000159666
myl10
myosin, light chain 10, regulatory
chr9_-_42894582 8.35 ENSDART00000144744
col5a2a
collagen, type V, alpha 2a
chr1_+_16683931 8.14 ENSDART00000103262
ENSDART00000145068
ENSDART00000169619
ENSDART00000010526
fat1a
FAT atypical cadherin 1a
chr10_+_18994733 7.70 ENSDART00000146517
dpysl2b
dihydropyrimidinase-like 2b
chr19_-_18316262 7.50 ENSDART00000151133
top2b
topoisomerase (DNA) II beta
chr12_-_30662709 7.24 ENSDART00000126466
entpd1
ectonucleoside triphosphate diphosphohydrolase 1
chr2_-_43110857 7.20 ENSDART00000098303
oc90
otoconin 90
chr13_-_13163676 6.75 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
chr1_+_44205158 6.49 ENSDART00000142820
wu:fc21g02
wu:fc21g02
chr16_+_23482744 6.43 ENSDART00000148961
s100a10b
S100 calcium binding protein A10b
chr1_-_48853800 6.43 ENSDART00000137357
zgc:175214
zgc:175214
chr5_+_34857986 6.42 ENSDART00000141239
erlin2
ER lipid raft associated 2
chr20_+_31366832 6.33 ENSDART00000133353
apobb.1
apolipoprotein Bb, tandem duplicate 1
chr6_-_43094573 6.24 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr23_+_21610798 6.09 ENSDART00000111966
arhgef10lb
Rho guanine nucleotide exchange factor (GEF) 10-like b
chr14_-_36037883 6.01 ENSDART00000173006
gpm6aa
glycoprotein M6Aa
chr8_-_16662185 5.97 ENSDART00000076542
rpe65b
retinal pigment epithelium-specific protein 65b
chr19_+_5399813 5.75 ENSDART00000145749
si:dkeyp-113d7.1
si:dkeyp-113d7.1
chr18_+_22617072 5.49 ENSDART00000128965
bcar1
breast cancer anti-estrogen resistance 1
chr23_+_32573474 5.44 ENSDART00000134811
si:dkey-261h17.1
si:dkey-261h17.1
chr10_+_21850059 5.43 ENSDART00000164634
ENSDART00000172513
pcdh1g32
protocadherin 1 gamma 32
chr21_+_27346176 5.37 ENSDART00000005682
actn3a
actinin alpha 3a
chr21_-_35806638 5.33 ENSDART00000172245
sgcd
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr19_-_19888074 5.31

chr14_+_11151485 5.27 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr16_+_24045774 5.19 ENSDART00000133484
apoeb
apolipoprotein Eb
chr24_+_10276926 5.18 ENSDART00000145771
ENSDART00000157350
CT573344.1
ENSDARG00000093108
chr7_-_57030751 5.06

chr23_+_36832325 4.95

chr13_+_22545318 4.95 ENSDART00000143312
zgc:193505
zgc:193505
chr14_-_7774262 4.84 ENSDART00000045109
zgc:92242
zgc:92242
chr11_-_41357639 4.81 ENSDART00000055709
her2
hairy-related 2
chr20_-_20412830 4.74 ENSDART00000114779
ENSDARG00000079369
ENSDARG00000079369
chr11_-_43331509 4.61

chr3_+_30790513 4.60 ENSDART00000130422
cldni
claudin i
chr4_-_8610868 4.59 ENSDART00000067322
fbxl14b
F-box and leucine-rich repeat protein 14b
chr24_-_33869817 4.57 ENSDART00000079283
tmeff1b
transmembrane protein with EGF-like and two follistatin-like domains 1b
chr5_-_36349284 4.55 ENSDART00000047269
h3f3b.1
H3 histone, family 3B.1
chr24_-_40968409 4.54 ENSDART00000169315
ENSDART00000171543
smyhc1
slow myosin heavy chain 1
chr13_+_28601627 4.52 ENSDART00000015773
ldb1a
LIM domain binding 1a
chr23_+_35609887 4.52 ENSDART00000179393
tuba1b
tubulin, alpha 1b
chr5_-_33006537 4.48 ENSDART00000048350
si:dkey-34e4.1
si:dkey-34e4.1
chr24_-_41448993 4.47 ENSDART00000041349
crygn2
crystallin, gamma N2
chr23_+_23730717 4.45

chr2_-_59531831 4.42 ENSDART00000168568
CU861477.1
ENSDARG00000100128
chr16_+_34569479 4.41 ENSDART00000041007
stmn1b
stathmin 1b
chr1_+_46537108 4.40

chr13_+_25298383 4.40

chr23_-_7892862 4.34 ENSDART00000157612
ENSDART00000165427
myt1b
myelin transcription factor 1b
chr13_-_13163801 4.33 ENSDART00000156968
fgfr3
fibroblast growth factor receptor 3
chr7_-_7442720 4.31 ENSDART00000091105
mfap3l
microfibrillar-associated protein 3-like
chr6_+_47845002 4.25 ENSDART00000140943
padi2
peptidyl arginine deiminase, type II
chr5_-_14148028 4.23 ENSDART00000113037
sema4c
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr19_-_18316039 4.23 ENSDART00000151133
top2b
topoisomerase (DNA) II beta
chr23_-_30119058 4.19 ENSDART00000103480
ccdc187
coiled-coil domain containing 187
chr11_+_24479085 4.19 ENSDART00000145217
ENSDARG00000070571
ENSDARG00000070571
chr25_+_17774363 4.11 ENSDART00000136797
btbd10a
BTB (POZ) domain containing 10a
chr14_-_26406720 4.11 ENSDART00000078563
neurog1
neurogenin 1
chr3_-_16100715 4.10 ENSDART00000146699
bckdhbl
branched chain keto acid dehydrogenase E1, beta polypeptide, like
chr2_+_20118917 4.08 ENSDART00000038648
ptbp2b
polypyrimidine tract binding protein 2b
chr22_+_17091411 4.07 ENSDART00000170076
frem1b
Fras1 related extracellular matrix 1b
chr8_-_12171624 3.96 ENSDART00000132824
dab2ipa
DAB2 interacting protein a
chr19_+_12995955 3.95 ENSDART00000132892
cthrc1a
collagen triple helix repeat containing 1a
chr7_+_39173765 3.94 ENSDART00000173748
tnnt3b
troponin T type 3b (skeletal, fast)
chr7_-_7164950 3.93 ENSDART00000012637
zgc:101810
zgc:101810
chr23_-_7889744 3.92 ENSDART00000164117
myt1b
myelin transcription factor 1b
chr2_-_30675594 3.92 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr22_-_37417903 3.91 ENSDART00000149948
FP102167.1
ENSDARG00000095844
chr14_-_40918015 3.87 ENSDART00000147389
tmem35
transmembrane protein 35
chr1_-_50147413 3.87 ENSDART00000080389
fam13a
family with sequence similarity 13, member A
chr6_+_29800606 3.87 ENSDART00000017424
ptmaa
prothymosin, alpha a
chr17_-_36988937 3.82 ENSDART00000145236
dpysl5a
dihydropyrimidinase-like 5a
chr7_-_32888309 3.81 ENSDART00000173461
BX571811.2
ENSDARG00000105655
chr18_-_15498798 3.79 ENSDART00000109410
endouc
endonuclease, polyU-specific C
chr20_+_34867305 3.70 ENSDART00000018304
mcm3
minichromosome maintenance complex component 3
chr23_+_20183765 3.70 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr25_+_19992389 3.61 ENSDART00000143441
tnni4b.2
troponin I4b, tandem duplicate 2
KN150173v1_-_16439 3.60 ENSDART00000162810
SNORD60
Small nucleolar RNA SNORD60
chr6_+_27156169 3.59 ENSDART00000088364
kif1aa
kinesin family member 1Aa
chr12_-_36138709 3.58 ENSDART00000130985
st6galnac
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase
chr11_+_37345024 3.57 ENSDART00000077496
hp1bp3
heterochromatin protein 1, binding protein 3
chr25_-_22089794 3.56 ENSDART00000139110
pkp3a
plakophilin 3a
chr1_-_34921848 3.56 ENSDART00000142154
frem3
Fras1 related extracellular matrix 3
chr18_+_40535215 3.55 ENSDART00000132833
vwa7
von Willebrand factor A domain containing 7
chr6_-_12616971 3.54 ENSDART00000056764
bmpr2a
bone morphogenetic protein receptor, type II a (serine/threonine kinase)
chr5_-_54890685 3.53 ENSDART00000148436
gna14
guanine nucleotide binding protein (G protein), alpha 14
chr21_+_25651712 3.52 ENSDART00000135123
si:dkey-17e16.17
si:dkey-17e16.17
chr6_-_43094926 3.52 ENSDART00000084389
lrrn1
leucine rich repeat neuronal 1
chr13_+_27102308 3.52 ENSDART00000145901
rin2
Ras and Rab interactor 2
chr11_+_30048913 3.49

chr6_+_54231519 3.43 ENSDART00000149542
pacsin1b
protein kinase C and casein kinase substrate in neurons 1b
chr15_-_4537178 3.42 ENSDART00000155619
ENSDART00000128602
tfdp2
transcription factor Dp-2
KN150230v1_-_36595 3.37

chr5_-_45905518 3.37 ENSDART00000111589
hapln1a
hyaluronan and proteoglycan link protein 1a
chr9_-_33584190 3.36 ENSDART00000138844
caska
calcium/calmodulin-dependent serine protein kinase a
chr13_+_27102377 3.36 ENSDART00000138043
rin2
Ras and Rab interactor 2
chr10_+_44195410 3.35 ENSDART00000046172
cryba4
crystallin, beta A4
chr2_+_3125365 3.35 ENSDART00000164308
ENSDART00000167649
pik3r3a
phosphoinositide-3-kinase, regulatory subunit 3a (gamma)
chr10_+_31362144 3.35

chr25_+_30746445 3.34 ENSDART00000156916
lsp1
lymphocyte-specific protein 1
chr10_-_36690119 3.32 ENSDART00000077161
rsf1b.1
remodeling and spacing factor 1b, tandem duplicate 1
chr8_+_23071884 3.32 ENSDART00000063075
zgc:100920
zgc:100920
chr6_+_30441419 3.31

chr16_-_38117896 3.30 ENSDART00000114266
plekho1b
pleckstrin homology domain containing, family O member 1b
chr12_-_7669319 3.25

chr16_-_32022177 3.25 ENSDART00000139664
styk1
serine/threonine/tyrosine kinase 1
chr22_-_3264630 3.23 ENSDART00000170992
si:zfos-943e10.1
si:zfos-943e10.1
chr9_+_4188263 3.23 ENSDART00000164543
kalrna
kalirin RhoGEF kinase a
chr11_+_24687813 3.17 ENSDART00000131431
sulf2a
sulfatase 2a
chr9_+_41301317 3.14 ENSDART00000000250
slc40a1
solute carrier family 40 (iron-regulated transporter), member 1
chr13_+_11305781 3.13

chr19_+_5399877 3.12 ENSDART00000145749
si:dkeyp-113d7.1
si:dkeyp-113d7.1
chr7_+_23843682 3.12 ENSDART00000173899
mrpl52
mitochondrial ribosomal protein L52
chr12_+_3043444 3.11 ENSDART00000149427
sgca
sarcoglycan, alpha
chr5_+_15167637 3.11 ENSDART00000127015
srrm4
serine/arginine repetitive matrix 4
chr6_+_30681170 3.09 ENSDART00000112294
ttc22
tetratricopeptide repeat domain 22
chr14_+_23980348 3.07 ENSDART00000160984
BX005228.1
ENSDARG00000105465
chr1_+_45063098 3.07 ENSDART00000084512
pkn1a
protein kinase N1a
chr5_+_64411412 3.07 ENSDART00000158484
BX001023.2
ENSDARG00000101163
chr21_-_20674965 3.05 ENSDART00000065649
ENSDARG00000044676
ENSDARG00000044676
chr3_-_12032297 3.00 ENSDART00000140123
hmox2b
heme oxygenase 2b
chr5_-_65349550 3.00 ENSDART00000164228
nrarpb
notch-regulated ankyrin repeat protein b
chr14_+_34146377 2.99 ENSDART00000131861
tmsb2
thymosin beta 2
chr1_+_39844690 2.98 ENSDART00000122059
scoca
short coiled-coil protein a
chr4_+_5733160 2.97 ENSDART00000110243
pou3f2a
POU class 3 homeobox 2a
chr12_-_7572970 2.96 ENSDART00000158095
slc16a9b
solute carrier family 16, member 9b
chr13_-_869704 2.93

chr17_+_16557246 2.92 ENSDART00000015729
ENSDART00000136874
foxn3
forkhead box N3
chr3_+_28450576 2.89 ENSDART00000150893
sept12
septin 12
chr14_+_47326080 2.88 ENSDART00000047525
cryba1l1
crystallin, beta A1, like 1
chr15_-_31687 2.87

chr5_-_31275147 2.85 ENSDART00000098160
tmem119b
transmembrane protein 119b
chr14_-_46407410 2.84 ENSDART00000173078
si:ch211-168f7.5
si:ch211-168f7.5
chr8_+_17148864 2.83 ENSDART00000140531
dimt1l
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr10_-_27261937 2.82

chr3_+_17387551 2.81 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr13_+_1051015 2.80 ENSDART00000033528
tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr3_+_14238188 2.78 ENSDART00000165452
ENSDART00000171726
tmem56b
transmembrane protein 56b
chr6_-_13654186 2.78 ENSDART00000150102
ENSDART00000041269
cryba2a
crystallin, beta A2a
chr10_+_4717800 2.77 ENSDART00000161789
palm2
paralemmin 2
chr2_-_59047356 2.77

chr10_+_22566353 2.75 ENSDART00000079514
efnb3a
ephrin-B3a
chr20_+_23599157 2.75 ENSDART00000149922
palld
palladin, cytoskeletal associated protein
chr4_+_4223606 2.74

chr24_-_24306469 2.74 ENSDART00000154149
BX323067.1
ENSDARG00000097984
chr19_+_15538967 2.73 ENSDART00000171403
lin28a
lin-28 homolog A (C. elegans)
chr7_-_26036887 2.71 ENSDART00000146935
zgc:77439
zgc:77439
chr17_-_29102320 2.71 ENSDART00000104204
foxg1a
forkhead box G1a
chr11_+_15478585 2.71 ENSDART00000163289
ENSDART00000066033
gdf11
growth differentiation factor 11
chr14_+_38445969 2.71 ENSDART00000164440
si:ch211-195b11.3
si:ch211-195b11.3
chr24_+_20414578 2.70 ENSDART00000131677
hhatlb
hedgehog acyltransferase-like, b
chr11_+_41401893 2.70 ENSDART00000171655
AL929185.1
ENSDARG00000103982
chr2_-_31037043 2.69 ENSDART00000087026
emilin2a
elastin microfibril interfacer 2a
chr4_+_18854068 2.67 ENSDART00000066977
bik
BCL2-interacting killer (apoptosis-inducing)
chr5_+_64411584 2.65 ENSDART00000158484
BX001023.2
ENSDARG00000101163
chr17_+_25503946 2.63

chr7_+_20272091 2.63 ENSDART00000052917
slc3a2a
solute carrier family 3 (amino acid transporter heavy chain), member 2a
chr15_-_16271208 2.62

chr7_-_69399273 2.61 ENSDART00000159823
ENSDART00000075178
ENSDART00000168942
ENSDART00000126739
tspan5a
tetraspanin 5a
chr8_-_13503775 2.61 ENSDART00000063834
ENSDARG00000043482
ENSDARG00000043482
chr23_-_43595189 2.61

chr14_-_425659 2.60

chr2_-_24614261 2.60 ENSDART00000099532
vmhc
ventricular myosin heavy chain
chr3_-_30027552 2.58 ENSDART00000103502
si:ch211-152f23.5
si:ch211-152f23.5
chr5_-_51109419 2.57 ENSDART00000163464
lhfpl2b
lipoma HMGIC fusion partner-like 2b
chr20_+_20600211 2.57 ENSDART00000036124
six1b
SIX homeobox 1b
chr5_-_40310638 2.56 ENSDART00000133183
parp8
poly (ADP-ribose) polymerase family, member 8
chr16_+_51317933 2.53 ENSDART00000157736
hmgn2
high mobility group nucleosomal binding domain 2
chr9_-_22311713 2.53 ENSDART00000108748
crygm2d18
crystallin, gamma M2d18
chr23_-_18945009 2.49 ENSDART00000080064
CR847953.1
ENSDARG00000057403
chr2_+_56339323 2.49 ENSDART00000123392
rab11bb
RAB11B, member RAS oncogene family, b
chr2_+_38178934 2.48 ENSDART00000044264
mmp14b
matrix metallopeptidase 14b (membrane-inserted)
chr15_-_39756101 2.48

chr3_+_19096030 2.47 ENSDART00000134514
smarca4a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4a
chr18_+_44656323 2.46 ENSDART00000059063
ehd2b
EH-domain containing 2b
chr19_-_20148533 2.46 ENSDART00000163790
evx1
even-skipped homeobox 1
chr9_-_13991784 2.45 ENSDART00000061156
raph1a
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a
chr10_-_42111408 2.45 ENSDART00000033121
morn3
MORN repeat containing 3
chr3_-_21217799 2.44 ENSDART00000114906
fam171a2a
family with sequence similarity 171, member A2a
chr9_-_22371512 2.44 ENSDART00000101809
crygm2d6
crystallin, gamma M2d6
chr13_-_31310439 2.43 ENSDART00000076571
rtn1a
reticulon 1a
chr17_-_44133941 2.43 ENSDART00000126097
otx2
orthodenticle homeobox 2
chr17_-_6219019 2.42

chr8_-_38168395 2.42 ENSDART00000155189
pdlim2
PDZ and LIM domain 2 (mystique)
chr24_+_24924379 2.42 ENSDART00000115165
amer2
APC membrane recruitment protein 2
chr8_+_14120313 2.41 ENSDART00000080832
si:dkey-6n6.2
si:dkey-6n6.2
chr9_-_3700395 2.41 ENSDART00000102900
sp5a
Sp5 transcription factor a
chr19_+_5375413 2.41 ENSDART00000141237
si:dkeyp-113d7.10
si:dkeyp-113d7.10
chr20_+_26408687 2.40

chr6_+_29420644 2.39 ENSDART00000065293
usp13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr3_-_40263048 2.38 ENSDART00000154236
AL928657.1
ENSDARG00000097119
chr5_-_30015572 2.38 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr20_+_53310252 2.36 ENSDART00000175125
CABZ01089116.1
ENSDARG00000106770
chr1_+_45503061 2.34 ENSDART00000010894
sox1b
SRY (sex determining region Y)-box 1b
chr17_-_35011682 2.33

chr8_-_18502159 2.32 ENSDART00000148802
ENSDART00000149081
ENSDART00000148962
nexn
nexilin (F actin binding protein)
chr15_+_28435937 2.32 ENSDART00000142298
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr16_+_16941228 2.31 ENSDART00000142155
myh14
myosin, heavy chain 14, non-muscle
chr15_-_18110169 2.31

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.3 GO:0003322 pancreatic A cell development(GO:0003322)
1.9 5.8 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
1.6 9.7 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
1.4 4.3 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
1.4 9.8 GO:0021553 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
1.4 5.5 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
1.3 11.8 GO:0007412 axon target recognition(GO:0007412)
1.2 7.2 GO:0071405 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
1.2 13.2 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208)
1.1 12.5 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
1.1 5.5 GO:0090527 actin filament reorganization(GO:0090527)
1.1 12.6 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) mitotic DNA replication(GO:1902969)
1.0 7.2 GO:0050482 icosanoid secretion(GO:0032309) arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
1.0 4.1 GO:0021516 dorsal spinal cord development(GO:0021516)
0.9 2.8 GO:0001659 temperature homeostasis(GO:0001659) sleep(GO:0030431)
0.9 2.8 GO:0035523 protein K29-linked deubiquitination(GO:0035523) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.9 2.7 GO:0050748 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.8 3.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.8 4.8 GO:0007405 neuroblast proliferation(GO:0007405)
0.8 3.0 GO:0006788 heme oxidation(GO:0006788)
0.7 5.9 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.7 2.8 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.7 0.7 GO:1903429 regulation of cell maturation(GO:1903429)
0.7 2.1 GO:0097037 heme export(GO:0097037)
0.7 4.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.6 4.2 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579)
0.6 2.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.6 4.5 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.5 2.1 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.5 3.0 GO:0042989 sequestering of actin monomers(GO:0042989)
0.5 3.0 GO:0061635 regulation of protein complex stability(GO:0061635)
0.5 3.4 GO:0060088 auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
0.5 7.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.5 6.3 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.5 1.9 GO:0032732 positive regulation of interleukin-1 production(GO:0032732)
0.5 3.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.4 3.1 GO:0048823 nucleate erythrocyte development(GO:0048823)
0.4 8.0 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.4 29.5 GO:0007601 visual perception(GO:0007601)
0.4 4.7 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.4 0.8 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.4 2.3 GO:0045056 transcytosis(GO:0045056)
0.4 7.6 GO:0003009 skeletal muscle contraction(GO:0003009)
0.4 0.7 GO:0043282 pharyngeal muscle development(GO:0043282)
0.4 2.2 GO:0010332 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.4 3.2 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.4 12.4 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.3 3.1 GO:0021754 facial nucleus development(GO:0021754)
0.3 3.9 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.3 1.3 GO:0010226 response to lithium ion(GO:0010226)
0.3 2.5 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.3 0.9 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.3 0.9 GO:0000390 spliceosomal complex disassembly(GO:0000390)
0.3 2.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.3 5.4 GO:0051764 actin crosslink formation(GO:0051764)
0.3 6.5 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.3 1.7 GO:0003232 bulbus arteriosus development(GO:0003232)
0.3 3.2 GO:0043584 nose development(GO:0043584)
0.2 3.0 GO:0010002 cardioblast differentiation(GO:0010002)
0.2 2.0 GO:0007398 ectoderm development(GO:0007398)
0.2 0.9 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.2 3.0 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2 0.9 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 2.3 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.2 0.7 GO:0021523 somatic motor neuron differentiation(GO:0021523) hypochord development(GO:0055016) radial glial cell differentiation(GO:0060019)
0.2 3.4 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.2 3.9 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.2 1.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 0.6 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.2 2.1 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 2.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 0.6 GO:0032355 response to estradiol(GO:0032355)
0.2 1.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 0.7 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.2 1.8 GO:0044030 regulation of DNA methylation(GO:0044030)
0.2 0.5 GO:0045905 positive regulation of translational termination(GO:0045905)
0.2 0.8 GO:0006582 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.2 0.9 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 2.8 GO:0015807 L-amino acid transport(GO:0015807)
0.1 1.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 4.0 GO:0048570 notochord morphogenesis(GO:0048570)
0.1 0.6 GO:0021512 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.1 0.8 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.1 2.0 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 4.4 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.5 GO:0043981 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1 0.8 GO:0051601 exocyst localization(GO:0051601)
0.1 1.4 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 3.2 GO:0043297 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.1 1.8 GO:0051310 metaphase plate congression(GO:0051310)
0.1 0.9 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 3.5 GO:0031167 rRNA methylation(GO:0031167)
0.1 0.6 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.1 2.7 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.1 2.0 GO:0010508 positive regulation of autophagy(GO:0010508)
0.1 1.6 GO:0070828 heterochromatin organization(GO:0070828)
0.1 2.0 GO:0010737 protein kinase A signaling(GO:0010737)
0.1 1.9 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 1.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 1.1 GO:0042551 neuron maturation(GO:0042551)
0.1 0.6 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) regulation of mitotic attachment of spindle microtubules to kinetochore(GO:1902423) positive regulation of attachment of mitotic spindle microtubules to kinetochore(GO:1902425) RNA localization to chromatin(GO:1990280)
0.1 4.0 GO:0032456 endocytic recycling(GO:0032456)
0.1 1.9 GO:0032944 regulation of mononuclear cell proliferation(GO:0032944) regulation of T cell proliferation(GO:0042129) regulation of lymphocyte proliferation(GO:0050670) regulation of leukocyte proliferation(GO:0070663)
0.1 1.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 1.3 GO:0070509 calcium ion import(GO:0070509)
0.1 2.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 3.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 0.8 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 0.8 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.1 3.2 GO:0007528 neuromuscular junction development(GO:0007528)
0.1 4.6 GO:0050919 negative chemotaxis(GO:0050919)
0.1 0.7 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.1 3.1 GO:0032543 mitochondrial translation(GO:0032543)
0.1 2.0 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 1.0 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.8 GO:0009649 entrainment of circadian clock(GO:0009649) entrainment of circadian clock by photoperiod(GO:0043153)
0.1 2.4 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 1.3 GO:0006270 DNA replication initiation(GO:0006270)
0.1 2.2 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 1.9 GO:0060401 cytosolic calcium ion transport(GO:0060401) calcium ion transport into cytosol(GO:0060402)
0.1 0.6 GO:0003319 cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.1 3.2 GO:0060028 convergent extension involved in axis elongation(GO:0060028)
0.1 2.4 GO:0048332 mesoderm morphogenesis(GO:0048332)
0.1 1.5 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.8 GO:0021681 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 3.0 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 1.8 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.1 0.9 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 3.2 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.1 0.2 GO:0061400 positive regulation of transcription from RNA polymerase II promoter in response to calcium ion(GO:0061400)
0.1 0.8 GO:0060974 cell migration involved in heart formation(GO:0060974)
0.1 1.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 5.3 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.2 GO:0045665 negative regulation of neuron differentiation(GO:0045665)
0.0 0.8 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.8 GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043280)
0.0 0.5 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 2.4 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.6 GO:0090398 cellular senescence(GO:0090398)
0.0 2.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 4.9 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 1.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 1.2 GO:1901880 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) negative regulation of protein complex disassembly(GO:0043242) actin filament capping(GO:0051693) regulation of protein depolymerization(GO:1901879) negative regulation of protein depolymerization(GO:1901880)
0.0 1.3 GO:0019722 calcium-mediated signaling(GO:0019722)
0.0 0.6 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 0.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.6 GO:0031103 axon regeneration(GO:0031103)
0.0 0.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 1.7 GO:0048278 vesicle docking(GO:0048278)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.3 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.2 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 0.5 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 1.4 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 2.0 GO:1901342 regulation of vasculature development(GO:1901342)
0.0 1.8 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 5.8 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 2.0 GO:0070507 regulation of microtubule cytoskeleton organization(GO:0070507)
0.0 1.5 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.9 GO:0035272 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.0 0.2 GO:0046627 regulation of insulin receptor signaling pathway(GO:0046626) negative regulation of insulin receptor signaling pathway(GO:0046627) regulation of cellular response to insulin stimulus(GO:1900076) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 1.5 GO:0030705 cytoskeleton-dependent intracellular transport(GO:0030705)
0.0 0.1 GO:0045010 actin nucleation(GO:0045010)
0.0 1.0 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.7 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 0.5 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.6 GO:0016358 dendrite development(GO:0016358)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.3 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.7 GO:0006414 translational elongation(GO:0006414)
0.0 0.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.3 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 3.5 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 0.3 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.7 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.7 GO:0009416 response to light stimulus(GO:0009416)
0.0 0.9 GO:0045055 regulated exocytosis(GO:0045055)
0.0 0.6 GO:0031101 fin regeneration(GO:0031101)
0.0 0.3 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 8.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
2.4 11.8 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
2.0 12.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
1.3 7.6 GO:0016012 sarcoglycan complex(GO:0016012)
0.9 6.0 GO:0044295 axonal growth cone(GO:0044295)
0.7 3.0 GO:0016586 RSC complex(GO:0016586)
0.7 2.2 GO:0071914 prominosome(GO:0071914)
0.7 12.6 GO:0042555 MCM complex(GO:0042555)
0.5 11.5 GO:0005861 troponin complex(GO:0005861)
0.3 1.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.3 1.1 GO:0043083 synaptic cleft(GO:0043083)
0.3 1.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 2.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.2 1.9 GO:0005921 gap junction(GO:0005921)
0.2 1.2 GO:0008091 spectrin(GO:0008091)
0.2 2.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 2.9 GO:0031010 ISWI-type complex(GO:0031010)
0.2 0.8 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.2 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.2 3.4 GO:0032587 ruffle membrane(GO:0032587)
0.1 0.6 GO:0097189 apoptotic body(GO:0097189)
0.1 1.0 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 2.9 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 1.8 GO:0036038 MKS complex(GO:0036038)
0.1 0.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 5.3 GO:0016459 myosin complex(GO:0016459)
0.1 12.1 GO:0031012 extracellular matrix(GO:0031012)
0.1 1.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 2.1 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.1 0.6 GO:0000803 sex chromosome(GO:0000803) inactive sex chromosome(GO:0098577)
0.1 5.3 GO:0044420 extracellular matrix component(GO:0044420)
0.1 3.3 GO:0031941 filamentous actin(GO:0031941)
0.1 0.6 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.1 1.4 GO:0000145 exocyst(GO:0000145)
0.1 1.2 GO:0045180 basal cortex(GO:0045180)
0.1 3.9 GO:0005581 collagen trimer(GO:0005581)
0.1 1.6 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.0 GO:0043209 myelin sheath(GO:0043209)
0.1 2.8 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.1 GO:0036379 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.1 3.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 0.8 GO:0014704 intercalated disc(GO:0014704)
0.1 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.1 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 4.9 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 3.5 GO:0014069 postsynaptic density(GO:0014069)
0.1 1.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.9 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.8 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 1.7 GO:0030424 axon(GO:0030424)
0.1 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 3.1 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.0 1.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 3.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.8 GO:0000922 spindle pole(GO:0000922)
0.0 2.3 GO:0030018 Z disc(GO:0030018)
0.0 3.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.9 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.3 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 8.7 GO:0005874 microtubule(GO:0005874)
0.0 0.4 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 1.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.5 GO:0055037 recycling endosome(GO:0055037)
0.0 3.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 1.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.2 GO:0005882 intermediate filament(GO:0005882)
0.0 20.6 GO:0005576 extracellular region(GO:0005576)
0.0 45.5 GO:0005886 plasma membrane(GO:0005886)
0.0 0.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 2.2 GO:0000786 nucleosome(GO:0000786)
0.0 1.8 GO:0045202 synapse(GO:0045202)
0.0 0.6 GO:0016605 PML body(GO:0016605)
0.0 1.1 GO:0030659 vesicle membrane(GO:0012506) cytoplasmic vesicle membrane(GO:0030659)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 11.8 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
2.2 8.9 GO:1990518 ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
1.9 5.8 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
1.9 13.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
1.6 6.3 GO:0070325 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
1.4 5.5 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.1 4.5 GO:0030274 LIM domain binding(GO:0030274)
1.1 3.2 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
1.0 3.9 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.9 26.4 GO:0005212 structural constituent of eye lens(GO:0005212)
0.9 4.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.8 3.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.8 3.0 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.7 11.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.7 7.2 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.7 3.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.7 2.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.7 10.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.7 7.2 GO:0004623 phospholipase A2 activity(GO:0004623)
0.6 1.8 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.6 4.1 GO:0070888 E-box binding(GO:0070888)
0.5 2.7 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.5 3.9 GO:0031013 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.5 1.8 GO:0008158 hedgehog receptor activity(GO:0008158)
0.4 2.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 3.5 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.4 1.1 GO:0048019 receptor inhibitor activity(GO:0030547) co-receptor binding(GO:0039706) receptor antagonist activity(GO:0048019)
0.3 3.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 3.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 8.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 1.1 GO:0099528 G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.3 1.9 GO:0035613 RNA stem-loop binding(GO:0035613)
0.3 0.8 GO:0001222 transcription corepressor binding(GO:0001222)
0.3 3.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3 1.0 GO:0050694 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.2 3.0 GO:0003785 actin monomer binding(GO:0003785)
0.2 6.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 8.6 GO:0015485 cholesterol binding(GO:0015485)
0.2 2.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 0.9 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
0.2 3.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.1 GO:0005523 tropomyosin binding(GO:0005523)
0.2 1.9 GO:0022829 wide pore channel activity(GO:0022829)
0.2 2.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 3.5 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
0.2 0.8 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.2 2.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 3.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 0.6 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.2 2.0 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.2 10.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 1.8 GO:0015026 coreceptor activity(GO:0015026)
0.2 0.5 GO:0000403 Y-form DNA binding(GO:0000403)
0.2 0.8 GO:0019215 intermediate filament binding(GO:0019215)
0.2 1.5 GO:0048495 Roundabout binding(GO:0048495)
0.2 3.1 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.2 3.3 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 7.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 0.9 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.2 1.9 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.2 1.8 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.6 GO:0015232 heme transporter activity(GO:0015232)
0.1 2.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 1.5 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 2.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 3.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 1.0 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.6 GO:0001097 TFIIH-class transcription factor binding(GO:0001097) poly(C) RNA binding(GO:0017130)
0.1 1.5 GO:0010181 FMN binding(GO:0010181)
0.1 1.1 GO:0005158 insulin receptor binding(GO:0005158)
0.1 4.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 0.8 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.1 0.8 GO:0052812 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.1 0.6 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.5 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.1 4.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 37.1 GO:0005509 calcium ion binding(GO:0005509)
0.1 1.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 3.2 GO:0005262 calcium channel activity(GO:0005262)
0.1 0.2 GO:0019807 aspartoacylase activity(GO:0019807)
0.1 3.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.9 GO:0051020 GTPase binding(GO:0051020)
0.1 12.4 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.8 GO:0019201 nucleotide kinase activity(GO:0019201)
0.0 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 9.6 GO:0015631 tubulin binding(GO:0015631)
0.0 4.8 GO:0003774 motor activity(GO:0003774)
0.0 3.8 GO:0031406 carboxylic acid binding(GO:0031406)
0.0 19.5 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.6 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.0 GO:0005179 hormone activity(GO:0005179)
0.0 33.7 GO:0001159 core promoter proximal region sequence-specific DNA binding(GO:0000987) core promoter proximal region DNA binding(GO:0001159)
0.0 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 6.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.7 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 1.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 7.6 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.8 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.8 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0005522 profilin binding(GO:0005522)
0.0 1.0 GO:0060090 binding, bridging(GO:0060090)
0.0 2.0 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 0.9 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.6 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 0.7 GO:0031625 ubiquitin protein ligase binding(GO:0031625)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.4 3.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 5.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 3.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.2 4.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 1.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.6 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 3.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 6.5 PID E2F PATHWAY E2F transcription factor network
0.1 1.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.5 PID FGF PATHWAY FGF signaling pathway
0.1 2.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 2.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 2.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 12.5 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.8 12.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.6 3.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.4 5.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.4 3.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.4 2.2 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.4 5.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 1.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 2.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 4.0 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.2 3.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.2 2.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.2 1.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 0.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.3 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 1.0 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 2.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.5 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.5 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 1.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME NCAM SIGNALING FOR NEURITE OUT GROWTH Genes involved in NCAM signaling for neurite out-growth