Project

DANIO-CODE

Navigation
Downloads

Results for sox1a+sox1b

Z-value: 0.96

Motif logo

logo of

Transcription factors associated with sox1a+sox1b

Gene Symbol Gene ID Gene Info
sox1b
ENSDARG00000008131 SRY-box transcription factor 1b
sox1a
ENSDARG00000069866 SRY-box transcription factor 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox1adr10_dc_chr9_+_21911860_219119820.766.3e-04Click!
sox1bdr10_dc_chr1_+_45503061_455031400.731.3e-03Click!

Activity profile of sox1a+sox1b motif

Sorted Z-values of sox1a+sox1b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of sox1a+sox1b

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr14_+_9115745 6.68 ENSDART00000123652
hmgn6
high mobility group nucleosome binding domain 6
chr1_-_31123999 3.76 ENSDART00000152493
nt5c2b
5'-nucleotidase, cytosolic IIb
chr14_-_9114872 3.46 ENSDART00000081158
sh3bgrl
SH3 domain binding glutamate-rich protein like
chr1_+_50835265 2.83 ENSDART00000162226
meis1a
Meis homeobox 1 a
chr2_+_7917776 2.80 ENSDART00000134178
ENSDART00000130781
eif4a2
eukaryotic translation initiation factor 4A, isoform 2
chr23_+_31888903 2.80 ENSDART00000075730
myb
v-myb avian myeloblastosis viral oncogene homolog
chr24_-_9151388 2.51 ENSDART00000149875
tgif1
TGFB-induced factor homeobox 1
chr14_+_26137608 2.37 ENSDART00000175459
gpr137
G protein-coupled receptor 137
chr14_+_6122948 2.12 ENSDART00000149783
ENSDART00000148461
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr19_+_12058673 1.67 ENSDART00000111568
polr2k
polymerase (RNA) II (DNA directed) polypeptide K
chr19_-_41887040 1.57 ENSDART00000062026
dlx5a
distal-less homeobox 5a
chr5_-_11723101 1.45 ENSDART00000161706
nos1
nitric oxide synthase 1 (neuronal)
chr14_+_20045365 1.35 ENSDART00000167637
aff2
AF4/FMR2 family, member 2
chr16_+_51319421 1.34

chr4_+_64539374 1.15 ENSDART00000170893
znf1070
zinc finger protein 1070
chr5_-_47106694 1.06 ENSDART00000165249
cox7c
cytochrome c oxidase, subunit VIIc
chr7_+_31154762 1.02 ENSDART00000138456
eif3jb
eukaryotic translation initiation factor 3, subunit Jb
chr11_+_37345024 0.99 ENSDART00000077496
hp1bp3
heterochromatin protein 1, binding protein 3
chr17_-_37107310 0.89 ENSDART00000151921
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr7_-_71092394 0.83 ENSDART00000081245
dhx15
DEAH (Asp-Glu-Ala-His) box helicase 15
chr5_+_29920060 0.78 ENSDART00000013431
hmbsa
hydroxymethylbilane synthase a
chr20_+_27194162 0.78 ENSDART00000024595
ubr7
ubiquitin protein ligase E3 component n-recognin 7
chr17_-_52735250 0.73

chr7_+_1228148 0.70 ENSDART00000143762
khnyn
KH and NYN domain containing
chr15_-_44957335 0.68

chr5_-_54151518 0.65

chr14_+_9115489 0.65 ENSDART00000123652
hmgn6
high mobility group nucleosome binding domain 6
chr19_-_12058215 0.64 ENSDART00000122962
si:ch73-49k18.1
si:ch73-49k18.1
chr11_-_45057353 0.64 ENSDART00000173106
rfc4
replication factor C (activator 1) 4
chr5_-_15774729 0.50 ENSDART00000090684
kremen1
kringle containing transmembrane protein 1
chr16_-_35634313 0.49 ENSDART00000162172
scmh1
sex comb on midleg homolog 1 (Drosophila)
chr12_+_30053414 0.47 ENSDART00000138252
ablim1b
actin binding LIM protein 1b
chr24_-_9151598 0.47 ENSDART00000149875
tgif1
TGFB-induced factor homeobox 1
chr2_+_31325256 0.47 ENSDART00000027090
yes1
YES proto-oncogene 1, Src family tyrosine kinase
chr9_+_2337092 0.43 ENSDART00000123340
atp5g3a
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9), genome duplicate a
chr14_+_46896395 0.41 ENSDART00000114790
flrt1b
fibronectin leucine rich transmembrane protein 1b
chr14_+_6122803 0.36 ENSDART00000149783
ENSDART00000148461
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr2_-_10020770 0.30 ENSDART00000046587
ap2m1a
adaptor-related protein complex 2, mu 1 subunit, a
chr25_-_36499819 0.30 ENSDART00000150178
wwox
WW domain containing oxidoreductase
chr19_+_20593503 0.26 ENSDART00000133873
tra2a
transformer 2 alpha homolog
chr20_-_40473621 0.23 ENSDART00000041229
fabp7b
fatty acid binding protein 7, brain, b
chr18_-_4851522 0.22 ENSDART00000143614
zbbx
zinc finger, B-box domain containing
chr11_+_31061296 0.20 ENSDART00000088093
sipa1l2
signal-induced proliferation-associated 1 like 2
chr9_-_27838603 0.18

chr16_+_35633745 0.17

chr7_-_71092598 0.15 ENSDART00000149682
dhx15
DEAH (Asp-Glu-Ala-His) box helicase 15
chr20_-_46345447 0.14 ENSDART00000100544
ENSDART00000152925
taar10
trace amine-associated receptor 10
chr12_+_26421153 0.13 ENSDART00000066264
chad
chondroadherin
chr7_+_57374714 0.13 ENSDART00000110623
arsj
arylsulfatase family, member J
chr14_+_6122644 0.09 ENSDART00000149783
ENSDART00000148461
abca1b
ATP-binding cassette, sub-family A (ABC1), member 1B
chr11_+_16082265 0.07 ENSDART00000081035
slc25a26
solute carrier family 25 (S-adenosylmethionine carrier), member 26
chr5_-_54151599 0.04

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0045658 regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.5 1.4 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.3 2.6 GO:0033700 phospholipid efflux(GO:0033700)
0.2 2.4 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.2 1.6 GO:0021628 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.2 3.0 GO:0072091 regulation of stem cell proliferation(GO:0072091)
0.1 1.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.8 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.1 0.5 GO:0048903 anterior lateral line neuromast development(GO:0048901) anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.1 3.1 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) serotonin receptor signaling pathway(GO:0007210)
0.0 0.9 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 2.8 GO:0009880 embryonic pattern specification(GO:0009880)
0.0 0.7 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.5 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 1.7 GO:0005736 DNA-directed RNA polymerase II, core complex(GO:0005665) DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 1.4 GO:0044309 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.0 8.8 GO:0000785 chromatin(GO:0000785)
0.0 2.4 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.3 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.0 0.5 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.5 3.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.4 2.6 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 7.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.8 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.1 0.6 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 3.8 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.9 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 2.8 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.0 0.7 GO:0004521 endoribonuclease activity(GO:0004521)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 3.0 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.4 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 3.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 1.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 1.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases