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Results for sox21a+sox21b

Z-value: 1.06

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Transcription factors associated with sox21a+sox21b

Gene Symbol Gene ID Gene Info
sox21b
ENSDARG00000008540 SRY-box transcription factor 21b
sox21a
ENSDARG00000031664 SRY-box transcription factor 21a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox21bdr10_dc_chr9_+_53736715_537367630.862.2e-05Click!
sox21adr10_dc_chr6_+_7257078_72571440.811.3e-04Click!

Activity profile of sox21a+sox21b motif

Sorted Z-values of sox21a+sox21b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of sox21a+sox21b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr15_+_28753020 3.57 ENSDART00000155815
nova2
neuro-oncological ventral antigen 2
chr8_-_49443058 3.12 ENSDART00000011453
sypb
synaptophysin b
chr12_-_37560192 2.85 ENSDART00000140353
sdk2b
sidekick cell adhesion molecule 2b
chr6_+_52235389 2.52 ENSDART00000056319
cox6c
cytochrome c oxidase subunit VIc
chr14_+_25168063 2.49 ENSDART00000173436
si:dkey-280e21.3
si:dkey-280e21.3
chr10_-_17527124 2.33 ENSDART00000137905
nt5c2l1
5'-nucleotidase, cytosolic II, like 1
chr24_-_12794057 2.20 ENSDART00000024084
pck2
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr16_-_42486580 2.14 ENSDART00000148475
cspg5a
chondroitin sulfate proteoglycan 5a
chr6_+_7742042 2.14 ENSDART00000112290
ENSDART00000062740
palm3
paralemmin 3
chr25_-_33920256 1.98

chr5_-_33225263 1.95 ENSDART00000139371
BX005445.1
ENSDARG00000095064
chr21_+_26352675 1.87 ENSDART00000077197
tmsb
thymosin, beta
chr4_+_5767840 1.85 ENSDART00000076494
ngs
notochord granular surface
chr10_+_43360137 1.81 ENSDART00000012522
vcanb
versican b
chr3_+_39425125 1.79 ENSDART00000146867
aldoaa
aldolase a, fructose-bisphosphate, a
chr4_+_5498355 1.74 ENSDART00000150785
mapk11
mitogen-activated protein kinase 11
chr16_-_40891298 1.64

chr8_+_39964695 1.63 ENSDART00000073782
ggt5a
gamma-glutamyltransferase 5a
KN149679v1_-_32359 1.61 ENSDART00000172177
surf4
surfeit gene 4
chr7_+_25794014 1.58 ENSDART00000174010
ENSDART00000173815
CT027989.1
ENSDARG00000105638
chr6_-_16156494 1.57

chr9_-_6683651 1.56 ENSDART00000061593
pou3f3a
POU class 3 homeobox 3a
chr5_-_15774816 1.55 ENSDART00000090684
kremen1
kringle containing transmembrane protein 1
chr1_-_4757890 1.51 ENSDART00000114035
mnx2b
motor neuron and pancreas homeobox 2b
chr4_-_5325164 1.50 ENSDART00000067375
osgep
O-sialoglycoprotein endopeptidase
chr16_-_42968807 1.50 ENSDART00000154757
txnipb
thioredoxin interacting protein b
chr15_+_32853646 1.44 ENSDART00000167515
postnb
periostin, osteoblast specific factor b
chr14_+_20045365 1.44 ENSDART00000167637
aff2
AF4/FMR2 family, member 2
chr15_-_16076874 1.43 ENSDART00000144138
hnf1ba
HNF1 homeobox Ba
chr8_-_28285565 1.41 ENSDART00000078545
lmod1a
leiomodin 1a (smooth muscle)
chr20_-_5184885 1.36 ENSDART00000114851
ccdc85cb
coiled-coil domain containing 85C, b
chr1_+_38834751 1.33 ENSDART00000137676
tenm3
teneurin transmembrane protein 3
chr9_-_55204516 1.28

chr1_+_33563354 1.28 ENSDART00000075584
kctd12.2
potassium channel tetramerisation domain containing 12.2
chr16_-_24280209 1.26 ENSDART00000048599
rps19
ribosomal protein S19
chr20_-_35938683 1.24 ENSDART00000037855
tnfrsf21
tumor necrosis factor receptor superfamily, member 21
chr12_+_16845837 1.19 ENSDART00000138174
slc16a12b
solute carrier family 16, member 12b
chr21_+_38770125 1.19 ENSDART00000149085
hnf1bb
HNF1 homeobox Bb
chr10_-_8336541 1.17 ENSDART00000163803
plpp1a
phospholipid phosphatase 1a
chr21_-_5852663 1.15 ENSDART00000130521
CACFD1
calcium channel flower domain containing 1
chr12_-_5383331 1.14 ENSDART00000152622
ENSDART00000028043
noc3l
NOC3-like DNA replication regulator
chr18_-_14868444 1.14 ENSDART00000045232
mtss1la
metastasis suppressor 1-like a
chr3_-_60197547 1.13

chr6_-_59510397 1.12 ENSDART00000170685
gli1
GLI family zinc finger 1
chr7_+_39139248 1.10 ENSDART00000165594
CT030188.1
ENSDARG00000099385
chr23_+_6861489 1.09 ENSDART00000092131
si:ch211-117c9.5
si:ch211-117c9.5
chr16_-_42968860 1.08 ENSDART00000102345
txnipb
thioredoxin interacting protein b
chr12_-_44867369 1.07 ENSDART00000154859
trim65
tripartite motif containing 65
chr16_-_37461878 1.05 ENSDART00000142916
si:ch211-208k15.1
si:ch211-208k15.1
chr1_-_13547500 1.04 ENSDART00000044896
camk2d2
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr25_-_12107407 1.03 ENSDART00000159800
ENSDART00000091727
ntrk3a
neurotrophic tyrosine kinase, receptor, type 3a
chr22_-_6977038 1.03 ENSDART00000133143
ENSDART00000146813
gpd1b
glycerol-3-phosphate dehydrogenase 1b
chr8_+_2428689 1.01 ENSDART00000081325
dynll1
dynein, light chain, LC8-type 1
KN150630v1_+_44324 1.00

chr6_-_2294751 0.99 ENSDART00000165223
pbx1b
pre-B-cell leukemia homeobox 1b
chr12_-_37124892 0.99 ENSDART00000146142
pmp22b
peripheral myelin protein 22b
chr16_-_38117896 0.96 ENSDART00000114266
plekho1b
pleckstrin homology domain containing, family O member 1b
chr2_-_18275994 0.95 ENSDART00000155124
ptprfb
protein tyrosine phosphatase, receptor type, f, b
chr20_-_51746555 0.95 ENSDART00000065231
disp1
dispatched homolog 1 (Drosophila)
chr9_-_23307419 0.93 ENSDART00000020884
lypd6
LY6/PLAUR domain containing 6
chr12_-_30897542 0.89 ENSDART00000145967
tcf7l2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr25_-_14948922 0.89 ENSDART00000161165
pax6a
paired box 6a
chr8_-_23744125 0.88 ENSDART00000141871
INAVA
innate immunity activator
chr21_-_8304754 0.87 ENSDART00000055328
nek6
NIMA-related kinase 6
chr14_-_49115338 0.86 ENSDART00000056712
etfdh
electron-transferring-flavoprotein dehydrogenase
chr14_-_2298998 0.82 ENSDART00000054891
pcdh2ab2
protocadherin 2 alpha b2
chr21_-_4086050 0.80 ENSDART00000099389
dnlz
DNL-type zinc finger
chr16_+_49423377 0.79 ENSDART00000015694
rab5ab
RAB5A, member RAS oncogene family, b
chr6_+_24299180 0.78 ENSDART00000167482
tgfbr3
transforming growth factor, beta receptor III
chr23_-_22020043 0.78 ENSDART00000148120
ephb2a
eph receptor B2a
chr11_-_33697442 0.78 ENSDART00000087597
col6a2
collagen, type VI, alpha 2
chr1_-_661529 0.76 ENSDART00000166786
ENSDART00000170483
appa
amyloid beta (A4) precursor protein a
chr18_-_17527321 0.74

chr18_+_12687027 0.73 ENSDART00000144246
tbxas1
thromboxane A synthase 1 (platelet)
chr13_-_18064929 0.72 ENSDART00000079902
slc25a16
solute carrier family 25 (mitochondrial carrier; Graves disease autoantigen), member 16
chr21_-_41994224 0.72 ENSDART00000092821
ENSDART00000165743
ENSDART00000075740
gabrg2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr21_+_27241416 0.71

chr25_-_21618526 0.70 ENSDART00000152011
DOCK4 (1 of many)
dedicator of cytokinesis 4
chr25_+_36872560 0.69 ENSDART00000163178
slc10a3
solute carrier family 10, member 3
chr6_-_52234513 0.68 ENSDART00000133554
tomm34
translocase of outer mitochondrial membrane 34
chr20_-_45757288 0.68 ENSDART00000124582
ENSDART00000100290
napbb
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr18_-_50527399 0.66 ENSDART00000033591
cd276
CD276 molecule
chr4_-_73683521 0.66

chr20_-_34898276 0.65 ENSDART00000048375
ENSDART00000132426
stmn4
stathmin-like 4
chr7_-_39266252 0.65 ENSDART00000173965
otog
otogelin
chr22_+_12773735 0.65 ENSDART00000005720
stat1a
signal transducer and activator of transcription 1a
chr6_+_48207747 0.65 ENSDART00000075172
cttnbp2nla
CTTNBP2 N-terminal like a
chr2_+_39653315 0.65 ENSDART00000077108
zgc:136870
zgc:136870
chr2_+_24718602 0.64 ENSDART00000022379
nr2f6a
nuclear receptor subfamily 2, group F, member 6a
chr14_-_50145578 0.63 ENSDART00000042421
ppp2ca
protein phosphatase 2, catalytic subunit, alpha isozyme
chr8_+_28046911 0.63 ENSDART00000078533
kcnd3
potassium voltage-gated channel, Shal-related subfamily, member 3
chr10_+_35332098 0.63 ENSDART00000077404
pora
P450 (cytochrome) oxidoreductase a
chr3_+_44468134 0.63 ENSDART00000164561
ENSDARG00000098547
ENSDARG00000098547
chr17_+_37268262 0.62 ENSDART00000104009
slc30a1b
solute carrier family 30 (zinc transporter), member 1b
chr17_+_44666606 0.62 ENSDART00000155096
tmem63c
transmembrane protein 63C
chr11_-_3339651 0.62

KN150708v1_+_30684 0.61

chr16_+_37632680 0.61 ENSDART00000169331
adgrb1a
adhesion G protein-coupled receptor B1a
chr13_+_49436597 0.60 ENSDART00000037559
ENSDART00000168799
ENSDART00000097845
ggps1
geranylgeranyl diphosphate synthase 1
chr3_-_20888014 0.59 ENSDART00000002393
rundc3aa
RUN domain containing 3Aa
chr15_-_35802739 0.58 ENSDART00000174714
CR848683.2
ENSDARG00000106192
chr23_+_25392850 0.57

chr25_-_22850980 0.57 ENSDART00000175228
CU462979.1
ENSDARG00000107627
chr8_-_32497168 0.56 ENSDART00000164826
RFESD (1 of many)
Rieske Fe-S domain containing
chr25_+_4711457 0.56 ENSDART00000168016
gnb5a
guanine nucleotide binding protein (G protein), beta 5a
chr5_+_5186074 0.55

chr12_-_9094842 0.55 ENSDART00000066471
adam8b
ADAM metallopeptidase domain 8b
chr14_-_11150618 0.55 ENSDART00000110424
si:ch211-153b23.4
si:ch211-153b23.4
chr18_+_35861883 0.53 ENSDART00000131121
ppp1r13l
protein phosphatase 1, regulatory subunit 13 like
chr21_-_25649117 0.52 ENSDART00000101205
phkg1b
phosphorylase kinase, gamma 1b (muscle)
chr12_-_48643687 0.52 ENSDART00000178135
ENSDART00000176040
CABZ01078412.1
ENSDARG00000107260
chr7_+_25793777 0.52 ENSDART00000174010
ENSDART00000173815
CT027989.1
ENSDARG00000105638
chr23_+_33457343 0.51 ENSDART00000114423
rapgef3
Rap guanine nucleotide exchange factor (GEF) 3
chr16_+_23683879 0.50 ENSDART00000131627
kcnn3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr6_-_2294717 0.49 ENSDART00000165223
pbx1b
pre-B-cell leukemia homeobox 1b
chr9_+_34832049 0.47 ENSDART00000100735
ENSDART00000133996
shox
short stature homeobox
chr8_+_23763721 0.47 ENSDART00000062968
si:ch211-163l21.8
si:ch211-163l21.8
chr1_+_13696269 0.47 ENSDART00000103346
fip1l1b
FIP1 like 1b (S. cerevisiae)
chr5_-_28167936 0.45 ENSDART00000043466
traf2a
Tnf receptor-associated factor 2a
chr6_+_29095988 0.43 ENSDART00000175422
rpl5b
ribosomal protein L5b
chr25_+_32348377 0.42 ENSDART00000162188
ETFA
electron transfer flavoprotein alpha subunit
chr8_+_1834454 0.42 ENSDART00000056208
snap29
synaptosomal-associated protein 29
chr6_-_52234640 0.42 ENSDART00000133554
tomm34
translocase of outer mitochondrial membrane 34
chr5_+_12028418 0.42 ENSDART00000131644
rfc5
replication factor C (activator 1) 5
chr5_-_56277572 0.41

chr21_-_2143830 0.41

chr19_-_25880088 0.41 ENSDART00000112915
UMAD1
UBAP1-MVB12-associated (UMA) domain containing 1
chr16_-_31763281 0.40 ENSDART00000169109
rbp5
retinol binding protein 1a, cellular
chr8_+_39478197 0.39

chr24_-_32115473 0.39 ENSDART00000168419
rsu1
Ras suppressor protein 1
chr15_+_926222 0.39 ENSDART00000156395
si:dkey-7i4.9
si:dkey-7i4.9
chr11_+_36781811 0.38 ENSDART00000109235
bicd2
bicaudal D homolog 2 (Drosophila)
chr8_+_16690670 0.38 ENSDART00000144621
smim15
small integral membrane protein 15
chr8_-_13182911 0.38 ENSDART00000090541
si:ch73-61d6.3
si:ch73-61d6.3
chr18_-_17527112 0.37

chr6_-_55704190 0.37

chr15_+_28753150 0.36 ENSDART00000060244
nova2
neuro-oncological ventral antigen 2
chr21_+_13196717 0.36 ENSDART00000163767
adora2ab
adenosine A2a receptor b
chr7_-_47900141 0.36 ENSDART00000174262
mtss1lb
metastasis suppressor 1-like b
chr19_+_2803373 0.35 ENSDART00000160847
hgh1
HGH1 homolog (S. cerevisiae)
chr4_+_59770753 0.35 ENSDART00000162832
znf1104
zinc finger protein 1104
chr25_+_34244186 0.34 ENSDART00000087364
wwp2
WW domain containing E3 ubiquitin protein ligase 2
chr18_+_29971911 0.34 ENSDART00000146431
ENSDART00000099285
atmin
ATM interactor
chr16_+_37519702 0.34

chr7_+_24864542 0.32 ENSDART00000164261
exoc6b
exocyst complex component 6B
chr12_-_8780030 0.32 ENSDART00000113148
jmjd1cb
jumonji domain containing 1Cb
chr16_+_37519812 0.32

chr6_-_52234826 0.31 ENSDART00000001803
tomm34
translocase of outer mitochondrial membrane 34
chr20_-_26521700 0.30 ENSDART00000110883
akap12b
A kinase (PRKA) anchor protein 12b
chr18_-_17410180 0.30 ENSDART00000060949
zfpm1
zinc finger protein, FOG family member 1
chr21_-_40653250 0.30 ENSDART00000162623
arxb
aristaless related homeobox b
chr8_+_39964882 0.30 ENSDART00000134452
ggt5a
gamma-glutamyltransferase 5a
chr8_-_19457039 0.29

chr18_+_38918883 0.29 ENSDART00000159202
myo5aa
myosin VAa
chr10_-_8476067 0.28 ENSDART00000108643
tctn1
tectonic family member 1
chr14_-_6831373 0.28 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr24_+_8764274 0.27 ENSDART00000140924
gnal
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr8_-_13183034 0.27 ENSDART00000090541
si:ch73-61d6.3
si:ch73-61d6.3
chr14_-_32414754 0.27 ENSDART00000160631
BX088596.1
ENSDARG00000099054
chr12_+_20461659 0.27 ENSDART00000170035
arsg
arylsulfatase G
chr14_-_2409585 0.26 ENSDART00000114302
pcdh2aa1
protocadherin 2 alpha a 1
chr14_-_6831308 0.26 ENSDART00000054803
trpt1
tRNA phosphotransferase 1
chr5_+_67129480 0.26

chr19_+_19620893 0.25 ENSDART00000161570
mrpl3
mitochondrial ribosomal protein L3
chr11_-_26124572 0.22 ENSDART00000115037
foxj3
forkhead box J3
chr24_-_5995073 0.21 ENSDART00000040865
pdss1
prenyl (decaprenyl) diphosphate synthase, subunit 1
chr6_+_6621888 0.21 ENSDART00000143359
sec23b
Sec23 homolog B, COPII coat complex component
chr13_-_19668751 0.20 ENSDART00000058032
fam204a
family with sequence similarity 204, member A
chr15_-_19162052 0.20

chr11_-_16261123 0.20 ENSDART00000115085
lrig1
leucine-rich repeats and immunoglobulin-like domains 1
chr14_-_8150455 0.19 ENSDART00000016727
eif1ad
eukaryotic translation initiation factor 1A domain containing
chr23_-_29931398 0.19 ENSDART00000109506
tmem201
transmembrane protein 201
chr25_+_26368695 0.18

chr4_+_14107347 0.18 ENSDART00000150748
CU469420.1
ENSDARG00000086259
chr5_-_30434967 0.18 ENSDART00000086534
cyb5d2
cytochrome b5 domain containing 2
chr7_+_39139117 0.17 ENSDART00000165594
CT030188.1
ENSDARG00000099385
chr21_-_39900518 0.17 ENSDART00000175055
CABZ01065291.1
ENSDARG00000107374
chr9_+_13762263 0.16 ENSDART00000141314
ENSDART00000138254
abi2a
abl-interactor 2a
chr18_-_17527155 0.15

chr17_-_8498935 0.14 ENSDART00000148990
ctbp2a
C-terminal binding protein 2a
chr15_+_23508351 0.14 ENSDART00000162997
phykpl
5-phosphohydroxy-L-lysine phospho-lyase
chr10_-_34927807 0.12 ENSDART00000138755
dclk1a
doublecortin-like kinase 1a
chr14_+_18956828 0.11 ENSDART00000005738
slitrk2
SLIT and NTRK-like family, member 2
chr6_-_7619366 0.11 ENSDART00000105232
myh9a
myosin, heavy chain 9a, non-muscle
chr19_-_2803212 0.11 ENSDART00000159253
exosc7
exosome component 7
chr13_-_36400356 0.11 ENSDART00000175311
pacs2
phosphofurin acidic cluster sorting protein 2
chr21_-_13133786 0.10 ENSDART00000023834
setb
SET nuclear proto-oncogene b
chr20_+_47639141 0.10 ENSDART00000043938
tram2
translocation associated membrane protein 2
chr24_+_39314937 0.10 ENSDART00000129371
CABZ01072827.1
ENSDARG00000087471
chr17_+_37268209 0.10 ENSDART00000104009
slc30a1b
solute carrier family 30 (zinc transporter), member 1b
chr17_+_8018808 0.10 ENSDART00000131200
myct1b
myc target 1b
chr18_-_1745485 0.10

chr11_-_25495956 0.10 ENSDART00000171935
brpf3a
bromodomain and PHD finger containing, 3a
chr6_-_39278397 0.09 ENSDART00000148531
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr15_-_44581550 0.09

chr4_+_14659537 0.09

chr7_-_25794648 0.09

chr13_-_49934345 0.09 ENSDART00000034541
gpatch11
G patch domain containing 11
chr13_-_14777916 0.09 ENSDART00000112771
ap5s1
adaptor-related protein complex 5, sigma 1 subunit
chr11_+_44696462 0.08 ENSDART00000158188
mgea5l
meningioma expressed antigen 5 (hyaluronidase) like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.6 1.9 GO:0019730 antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
0.6 2.2 GO:0046327 propionate metabolic process(GO:0019541) propionate catabolic process(GO:0019543) glycerol biosynthetic process from pyruvate(GO:0046327) cellular response to dexamethasone stimulus(GO:0071549)
0.5 1.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.5 3.9 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.5 1.9 GO:0006751 glutathione catabolic process(GO:0006751)
0.4 1.3 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.4 1.2 GO:0050864 regulation of B cell activation(GO:0050864)
0.4 1.1 GO:0021563 glossopharyngeal nerve development(GO:0021563) abducens nucleus development(GO:0021742)
0.3 1.0 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.3 1.5 GO:0048901 anterior lateral line neuromast development(GO:0048901) anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.2 0.7 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.2 1.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.2 1.8 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 0.9 GO:0010226 response to lithium ion(GO:0010226)
0.2 0.7 GO:0032475 otolith formation(GO:0032475)
0.2 1.0 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.2 1.0 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 0.6 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.2 1.0 GO:1901739 regulation of myoblast fusion(GO:1901739)
0.2 0.7 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.2 1.0 GO:0042694 muscle cell fate specification(GO:0042694)
0.1 1.3 GO:0072098 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.1 1.0 GO:1990089 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.1 0.9 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 0.9 GO:0022904 respiratory electron transport chain(GO:0022904)
0.1 0.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 1.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 1.3 GO:0045646 central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284) regulation of erythrocyte differentiation(GO:0045646)
0.1 0.5 GO:0044090 positive regulation of vacuole organization(GO:0044090)
0.1 0.9 GO:0060827 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823) regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 1.9 GO:0060035 notochord cell development(GO:0060035)
0.1 1.4 GO:0016203 muscle attachment(GO:0016203)
0.1 1.5 GO:0097178 ruffle assembly(GO:0097178)
0.1 1.8 GO:0030388 thigmotaxis(GO:0001966) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.7 GO:0051932 synaptic transmission, GABAergic(GO:0051932) regulation of postsynaptic membrane potential(GO:0060078)
0.1 1.3 GO:0021986 habenula development(GO:0021986)
0.1 0.5 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 3.0 GO:0007416 synapse assembly(GO:0007416)
0.1 0.3 GO:0032060 bleb assembly(GO:0032060) slow muscle cell migration(GO:1904969)
0.1 0.6 GO:0071357 response to type I interferon(GO:0034340) type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.1 0.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.3 GO:0030219 megakaryocyte differentiation(GO:0030219)
0.1 0.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.1 0.4 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.5 GO:0098787 mRNA cleavage involved in mRNA processing(GO:0098787) pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 2.2 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.0 0.7 GO:0050852 T cell receptor signaling pathway(GO:0050852)
0.0 2.5 GO:0006119 oxidative phosphorylation(GO:0006119)
0.0 0.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 3.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.7 GO:1902749 regulation of cell cycle G2/M phase transition(GO:1902749)
0.0 0.4 GO:0001973 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 2.3 GO:0071466 cellular response to xenobiotic stimulus(GO:0071466)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.4 GO:0072393 microtubule anchoring at microtubule organizing center(GO:0072393)
0.0 0.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.6 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0 0.7 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.7 GO:0070830 apical junction assembly(GO:0043297) bicellular tight junction assembly(GO:0070830)
0.0 0.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.2 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.5 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.0 1.1 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 1.4 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.7 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.3 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.8 GO:1903844 regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.0 1.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.5 GO:0030282 bone mineralization(GO:0030282)
0.0 0.8 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.8 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.1 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0035301 Hedgehog signaling complex(GO:0035301)
0.2 0.9 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.2 1.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.2 0.8 GO:0098842 postsynaptic early endosome(GO:0098842)
0.2 1.0 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 0.7 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.7 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.1 1.4 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.5 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 1.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.8 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.3 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.4 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 1.2 GO:0005901 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 0.3 GO:0098802 plasma membrane receptor complex(GO:0098802)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.0 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 3.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.9 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 8.6 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 2.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.9 GO:0000502 proteasome complex(GO:0000502)
0.0 0.5 GO:0043025 neuronal cell body(GO:0043025)
0.0 4.0 GO:0045202 synapse(GO:0045202)
0.0 1.7 GO:0043005 neuron projection(GO:0043005)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0036374 peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.6 2.2 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.3 0.9 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.3 2.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.3 1.4 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.3 1.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.2 0.7 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.2 1.0 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2 1.8 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 0.7 GO:0008503 benzodiazepine receptor activity(GO:0008503) GABA-gated chloride ion channel activity(GO:0022851)
0.2 0.9 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.2 2.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 0.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 1.9 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.9 GO:0048039 ubiquinone binding(GO:0048039)
0.1 3.1 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.6 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 1.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.7 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 1.4 GO:0005523 tropomyosin binding(GO:0005523)
0.1 0.4 GO:0008665 tRNA 2'-phosphotransferase activity(GO:0000215) 2'-phosphotransferase activity(GO:0008665)
0.1 0.4 GO:0008097 5S rRNA binding(GO:0008097)
0.1 1.0 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 0.6 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 0.6 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.4 GO:0034452 dynactin binding(GO:0034452)
0.1 1.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.4 GO:0016918 retinal binding(GO:0016918)
0.1 1.5 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.2 GO:0005521 lamin binding(GO:0005521)
0.1 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.4 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.8 GO:0051087 chaperone binding(GO:0051087)
0.0 1.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.8 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.2 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 1.7 GO:0008201 heparin binding(GO:0008201)
0.0 0.1 GO:0004471 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 1.4 GO:0031072 heat shock protein binding(GO:0031072)
0.0 2.8 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.9 GO:0008013 beta-catenin binding(GO:0008013)
0.0 1.6 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 0.7 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.7 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 1.1 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0051018 protein kinase A binding(GO:0051018)
0.0 3.2 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 2.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.9 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.5 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.0 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.7 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 0.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 3.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 0.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.4 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.5 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex