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Results for sox32

Z-value: 0.83

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Transcription factors associated with sox32

Gene Symbol Gene ID Gene Info
sox32
ENSDARG00000100591 SRY-box transcription factor 32

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox32dr10_dc_chr7_-_58524285_58524309-0.136.3e-01Click!

Activity profile of sox32 motif

Sorted Z-values of sox32 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of sox32

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_-_11113032 3.62 ENSDART00000027598
tpm3
tropomyosin 3
chr15_-_23711689 3.27 ENSDART00000128644
ckmb
creatine kinase, muscle b
chr23_-_26150495 2.87 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr2_+_33057931 2.61

chr21_-_41286846 2.45 ENSDART00000167339
msx2b
muscle segment homeobox 2b
chr12_+_29994735 2.40 ENSDART00000042572
ENSDART00000153025
ablim1b
actin binding LIM protein 1b
chr13_-_25067585 2.13 ENSDART00000159585
adka
adenosine kinase a
chr1_-_49004615 1.94 ENSDART00000134399
slkb
STE20-like kinase b
chr17_+_27417635 1.91 ENSDART00000052446
vgll2b
vestigial-like family member 2b
chr9_+_11616740 1.89 ENSDART00000146585
si:dkey-69o16.5
si:dkey-69o16.5
chr15_-_35394535 1.77 ENSDART00000144153
mff
mitochondrial fission factor
chr10_+_4962403 1.76 ENSDART00000134679
CU074419.2
ENSDARG00000093688
chr25_-_17483202 1.68 ENSDART00000073684
mmp15a
matrix metallopeptidase 15a
KN149968v1_+_15749 1.50 ENSDART00000168977
ENSDARG00000102503
ENSDARG00000102503
chr24_-_36938495 1.50 ENSDART00000112694
fam171a2b
family with sequence similarity 171, member A2b
chr25_-_28054271 1.45

chr25_-_22541525 1.40 ENSDART00000073583
islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr11_+_10557530 1.27 ENSDART00000132365
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr19_-_42892975 1.24 ENSDART00000131715
psmb4
proteasome subunit beta 4
chr14_+_6239755 1.16 ENSDART00000097214
adam19b
ADAM metallopeptidase domain 19b
chr24_+_35899507 1.16 ENSDART00000122408
si:dkeyp-7a3.1
si:dkeyp-7a3.1
chr2_-_42784609 1.15

chr10_+_31362144 1.13

chr8_+_13465718 1.09 ENSDART00000034740
fut9d
fucosyltransferase 9d
chr5_-_67233396 1.09 ENSDART00000051833
ENSDART00000124890
gsx1
GS homeobox 1
chr19_-_19883594 1.01

chr19_+_5562107 0.99 ENSDART00000082080
jupb
junction plakoglobin b
chr10_-_7954888 0.98 ENSDART00000139661
slc35e4
solute carrier family 35, member E4
chr19_-_10941519 0.97 ENSDART00000169118
ENSDART00000160599
CU855694.1
ENSDARG00000098513
chr18_-_40493952 0.94

chr12_+_26530620 0.81 ENSDART00000046959
arhgap12b
Rho GTPase activating protein 12b
chr7_-_18448121 0.75 ENSDART00000112359
si:ch211-119e14.9
si:ch211-119e14.9
chr11_+_44108192 0.72 ENSDART00000165219
ENSDART00000160678
srsf7b
serine/arginine-rich splicing factor 7b
chr2_-_25340798 0.70 ENSDART00000169711
ENSDART00000144795
ENSDART00000111507
slc35g2a
solute carrier family 35, member G2a
chr25_-_22541628 0.68 ENSDART00000163001
islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr12_+_29994880 0.67 ENSDART00000042572
ENSDART00000153025
ablim1b
actin binding LIM protein 1b
KN150630v1_+_44324 0.66

chr15_-_37949371 0.65 ENSDART00000031418
hsc70
heat shock cognate 70
chr6_+_44891278 0.65

chr8_+_16690670 0.64 ENSDART00000144621
smim15
small integral membrane protein 15
chr2_-_27730279 0.57 ENSDART00000147100
toe1
target of EGR1, member 1 (nuclear)
chr3_-_53467621 0.55 ENSDART00000032788
rdh8a
retinol dehydrogenase 8a
chr21_-_19293600 0.54 ENSDART00000101462
mrps18c
mitochondrial ribosomal protein S18C
chr20_-_4723724 0.51 ENSDART00000147071
ak7a
adenylate kinase 7a
chr22_+_699548 0.47 ENSDART00000017305
znf76
zinc finger protein 76
chr19_-_29849858 0.47 ENSDART00000052108
ENSDART00000171908
fndc5b
fibronectin type III domain containing 5b
chr2_+_17129963 0.44 ENSDART00000145778
eif4g1a
eukaryotic translation initiation factor 4 gamma, 1a
chr19_-_29849805 0.42 ENSDART00000114442
fndc5b
fibronectin type III domain containing 5b
chr9_+_33049445 0.40 ENSDART00000168992
si:dkey-145p14.5
si:dkey-145p14.5
chr20_+_571020 0.40 ENSDART00000152149
si:dkey-121j17.6
si:dkey-121j17.6
chr9_-_23222916 0.39 ENSDART00000022392
ENSDART00000122036
rnd3b
Rho family GTPase 3b
chr9_+_11616570 0.38 ENSDART00000146585
si:dkey-69o16.5
si:dkey-69o16.5
chr4_+_27111238 0.37 ENSDART00000141908
alg12
ALG12, alpha-1,6-mannosyltransferase
chr2_-_42784707 0.37

chr9_+_33049549 0.34 ENSDART00000121751
si:dkey-145p14.5
si:dkey-145p14.5
chr7_+_17923953 0.34 ENSDART00000109171
rce1a
Ras converting CAAX endopeptidase 1a
chr5_-_1296190 0.34

chr16_+_40074850 0.28 ENSDART00000110100
hint3
histidine triad nucleotide binding protein 3
chr10_+_15106739 0.22 ENSDART00000128967
parm1
prostate androgen-regulated mucin-like protein 1
chr22_-_12837665 0.20 ENSDART00000145156
ENSDART00000137280
glsa
glutaminase a
chr21_-_32244805 0.15 ENSDART00000178765
BX927388.2
ENSDARG00000107266
chr1_+_16983711 0.09 ENSDART00000030665
slc25a4
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
chr7_+_41141295 0.07 ENSDART00000083967
chpf2
chondroitin polymerizing factor 2
chr22_+_5652765 0.06 ENSDART00000131308
dnase1l4.2
deoxyribonuclease 1 like 4, tandem duplicate 2
chr15_-_21756778 0.06 ENSDART00000039865
sdhdb
succinate dehydrogenase complex, subunit D, integral membrane protein b
chr8_-_16614882 0.05 ENSDART00000135319
osbpl9
oxysterol binding protein-like 9
chr10_+_31362087 0.04

chr7_-_52113622 0.03 ENSDART00000174186
wdr93
WD repeat domain 93
chr19_+_10941495 0.00 ENSDART00000169962
si:ch73-347e22.4
si:ch73-347e22.4

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0044209 AMP salvage(GO:0044209)
0.4 3.3 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.2 1.1 GO:0036065 fucosylation(GO:0036065)
0.1 1.7 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 3.1 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.1 3.6 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 0.5 GO:0008210 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.1 0.7 GO:0042026 protein refolding(GO:0042026)
0.1 1.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 1.2 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.4 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.2 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 2.1 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.2 GO:0043650 dicarboxylic acid biosynthetic process(GO:0043650)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.6 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0015860 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) purine-containing compound transmembrane transport(GO:0072530) mitochondrial ATP transmembrane transport(GO:1990544)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.5 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.2 GO:0005839 proteasome core complex(GO:0005839)
0.0 3.6 GO:0005884 actin filament(GO:0005884)
0.0 0.6 GO:0015030 Cajal body(GO:0015030)
0.0 1.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0004001 adenosine kinase activity(GO:0004001)
0.4 3.3 GO:0004111 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.4 1.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 2.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.5 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 0.5 GO:0004127 cytidylate kinase activity(GO:0004127)
0.1 1.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 3.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 6.7 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471)
0.0 2.1 GO:0017171 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 0.9 GO:0005179 hormone activity(GO:0005179)
0.0 0.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 1.0 GO:0015297 antiporter activity(GO:0015297)
0.0 0.4 GO:0000030 mannosyltransferase activity(GO:0000030)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 2.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.2 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.4 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein