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DANIO-CODE

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Results for sox4a+sox4b

Z-value: 0.74

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Transcription factors associated with sox4a+sox4b

Gene Symbol Gene ID Gene Info
ENSDARG00000004588 SRY-box transcription factor 4a
ENSDARG00000098834 SRY-box transcription factor 4b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sox4adr10_dc_chr19_-_29205158_29205231-0.656.1e-03Click!
sox4bdr10_dc_chr16_+_68014_68039-0.391.4e-01Click!

Activity profile of sox4a+sox4b motif

Sorted Z-values of sox4a+sox4b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of sox4a+sox4b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_43471879 1.25 ENSDART00000166324
catenin (cadherin-associated protein), delta 1
chr14_-_32755189 1.21 ENSDART00000074720
discs, large homolog 3 (Drosophila)
chr14_+_14850200 1.18 ENSDART00000167966
zgc:158852
chr12_+_30673985 1.17 ENSDART00000160422
aldehyde dehydrogenase 18 family, member A1
chr8_+_29626848 1.14 ENSDART00000139029
ENSDART00000091409
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr16_+_35582277 1.02 ENSDART00000167001
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr16_+_35582648 1.01 ENSDART00000171675
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr23_-_36349563 1.00

chr5_+_3567992 0.99 ENSDART00000129329
RPA interacting protein
chr22_-_6995611 0.99 ENSDART00000003422
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr3_-_27515161 0.95 ENSDART00000151027
si:ch211-157c3.4
chr3_-_15960491 0.92 ENSDART00000064838
LIM and SH3 protein 1
chr14_+_38509671 0.88

chr1_+_43471798 0.87 ENSDART00000166324
catenin (cadherin-associated protein), delta 1
chr8_-_44617324 0.86 ENSDART00000063396
BCL2-associated athanogene 4
chr7_-_64745132 0.86 ENSDART00000112166
family with sequence similarity 60, member A, like
chr23_-_34017934 0.84 ENSDART00000133223
ENSDARG00000070393
chr16_-_47446494 0.83 ENSDART00000032188
si:dkey-256h2.1
chr7_-_69883542 0.82

chr7_-_24724911 0.82 ENSDART00000173791
REST corepressor 2
chr23_-_35384257 0.80 ENSDART00000113643
F-box protein 25
chr17_+_7377230 0.79 ENSDART00000157123
SNF2 histone linker PHD RING helicase
chr24_+_19270877 0.78

chr5_-_22099244 0.77 ENSDART00000161298
non-POU domain containing, octamer-binding
chr14_+_38510523 0.77

chr5_+_22541236 0.77 ENSDART00000171719
alpha thalassemia/mental retardation syndrome X-linked, like
chr14_-_32755454 0.76 ENSDART00000074720
discs, large homolog 3 (Drosophila)
chr21_-_37341980 0.75 ENSDART00000076483
zgc:77151
chr8_-_44617367 0.73 ENSDART00000063396
BCL2-associated athanogene 4
chr1_-_22617455 0.73 ENSDART00000137567
small integral membrane protein 14
chr7_-_31346802 0.73 ENSDART00000111388
immunoglobulin superfamily, DCC subclass, member 3
chr4_-_25921887 0.72 ENSDART00000175487
FYVE, RhoGEF and PH domain containing 6
chr3_+_60299938 0.70 ENSDART00000053482
TSEN54 tRNA splicing endonuclease subunit
chr5_+_44246311 0.69 ENSDART00000145299
ENSDART00000136521
KN motif and ankyrin repeat domains 1a
chr7_-_69883581 0.69

chr16_-_33151404 0.68 ENSDART00000145055
proline-rich nuclear receptor coactivator 2
chr7_-_31346844 0.67 ENSDART00000111388
immunoglobulin superfamily, DCC subclass, member 3
chr1_+_18390488 0.67 ENSDART00000002886
ENSDART00000158745
exosome component 9
chr4_-_25921780 0.66 ENSDART00000175487
FYVE, RhoGEF and PH domain containing 6
chr2_-_19585211 0.65 ENSDART00000169384
cell division cycle 20 homolog
chr16_+_35582411 0.64 ENSDART00000171675
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4b
chr25_+_15176959 0.62 ENSDART00000045659
t-complex 11, testis-specific-like 1
chr5_-_66070385 0.62 ENSDART00000032909
K(lysine) acetyltransferase 5b
chr16_-_55211053 0.62 ENSDART00000156533
keratinocyte differentiation factor 1a
chr19_-_18689437 0.61 ENSDART00000016135
nuclear factor, erythroid 2-like 3
chr24_-_21828216 0.59 ENSDART00000030592
acyl-CoA thioesterase 9, tandem duplicate 1
chr5_-_18393623 0.59 ENSDART00000010101
ENSDART00000099434
acetoacetyl-CoA synthetase
chr7_-_73628151 0.59 ENSDART00000123136
Histone H2B 1/2
chr23_-_16755868 0.59 ENSDART00000020810
syndecan binding protein (syntenin) 2
chr20_+_6543305 0.58 ENSDART00000135005
ENSDART00000166356
si:ch211-191a24.4
chr20_-_3301951 0.58 ENSDART00000123096
myristoylated alanine-rich protein kinase C substrate a
chr1_+_43471906 0.58 ENSDART00000166324
catenin (cadherin-associated protein), delta 1
chr1_+_43472177 0.57 ENSDART00000170512
catenin (cadherin-associated protein), delta 1
chr7_+_10320931 0.56 ENSDART00000173125
zinc finger, AN1-type domain 6
chr1_+_43471683 0.56 ENSDART00000166324
catenin (cadherin-associated protein), delta 1
chr6_-_6818607 0.56 ENSDART00000151822
tubulin, alpha 8 like 4
chr19_+_7717962 0.54 ENSDART00000112404
cingulin b
chr1_+_43471754 0.53 ENSDART00000166324
catenin (cadherin-associated protein), delta 1
chr8_+_29626894 0.53 ENSDART00000139029
ENSDART00000091409
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr4_-_25921852 0.52 ENSDART00000175487
FYVE, RhoGEF and PH domain containing 6
chr5_-_27549500 0.52 ENSDART00000051515
zgc:110329
chr13_-_43503453 0.52 ENSDART00000127930
ENSDART00000084474
family with sequence similarity 160, member B1
chr3_+_30187036 0.52 ENSDART00000151006
ENSDARG00000096295
chr6_-_9046536 0.51 ENSDART00000159506
coiled-coil domain containing 14
chr23_-_3815871 0.50 ENSDART00000137826
high mobility group AT-hook 1a
chr5_-_22466262 0.50 ENSDART00000172549
si:dkey-237j10.2
chr12_-_22279843 0.50 ENSDART00000153194
si:dkey-38p12.3
chr20_-_3301898 0.49 ENSDART00000123096
myristoylated alanine-rich protein kinase C substrate a
chr6_-_8008902 0.49 ENSDART00000151358
ral guanine nucleotide dissociation stimulator-like 3a
chr4_-_15005050 0.49 ENSDART00000067048
kelch domain containing 10
chr5_+_20319483 0.49 ENSDART00000142894
LIM domain kinase 2
chr16_+_42567707 0.48 ENSDART00000166640
si:ch211-215k15.5
chr24_+_26223767 0.48

chr12_-_22279890 0.48 ENSDART00000153194
si:dkey-38p12.3
chr16_+_26858575 0.47 ENSDART00000138496
RAD54 homolog B (S. cerevisiae)
chr23_-_10810190 0.47 ENSDART00000140745
eukaryotic translation initiation factor 4E family member 3
chr18_+_18416922 0.46 ENSDART00000080174
nedd4 binding protein 1
chr25_+_15177176 0.46 ENSDART00000045659
t-complex 11, testis-specific-like 1
chr8_-_44617200 0.44 ENSDART00000063396
BCL2-associated athanogene 4
chr14_+_38510427 0.44

chr1_+_30840656 0.44 ENSDART00000075286
solute carrier family 2 (facilitated glucose transporter), member 15b
chr22_-_7976467 0.44 ENSDART00000162028
sc:d217
chr1_-_46260853 0.43

chr2_-_24413154 0.43 ENSDART00000145526
solute carrier family 12 (potassium/chloride transporter), member 7a
chr12_+_10078043 0.43 ENSDART00000152369
si:dkeyp-118b1.2
chr3_+_18657831 0.42 ENSDART00000055757
transportin 2 (importin 3, karyopherin beta 2b)
chr5_-_18393705 0.41 ENSDART00000010101
ENSDART00000099434
acetoacetyl-CoA synthetase
chr2_+_43355846 0.41 ENSDART00000056402
par-3 family cell polarity regulator alpha, b
chr7_-_31669675 0.40 ENSDART00000131009
brain-derived neurotrophic factor
chr3_-_52406525 0.40 ENSDART00000138018
zgc:113210
chr7_-_31346991 0.39 ENSDART00000111388
immunoglobulin superfamily, DCC subclass, member 3
chr13_+_15802079 0.39 ENSDART00000131390
fidgetin-like 1
chr2_+_38019437 0.39 ENSDART00000139564
DDB1 and CUL4 associated factor 8
chr14_+_14536088 0.38 ENSDART00000158291
stem-loop binding protein
chr14_+_6656429 0.38 ENSDART00000150050
heterogeneous nuclear ribonucleoprotein A/Ba
chr9_+_27518890 0.38 ENSDART00000111039
GTP binding protein 8 (putative)
chr14_-_32755370 0.37 ENSDART00000074720
discs, large homolog 3 (Drosophila)
chr13_+_762105 0.37

chr19_-_31212648 0.36 ENSDART00000125893
ENSDART00000145581
tRNA isopentenyltransferase 1
chr17_-_49994799 0.36

chr1_+_30840599 0.36 ENSDART00000075286
solute carrier family 2 (facilitated glucose transporter), member 15b
chr8_+_29626728 0.36 ENSDART00000139029
ENSDART00000091409
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 a
chr23_-_36350288 0.36 ENSDART00000110478
zgc:174906
chr5_-_7591547 0.36 ENSDART00000158447
nipped-B homolog a (Drosophila)
chr7_+_10320888 0.36 ENSDART00000173125
zinc finger, AN1-type domain 6
chr1_-_17073539 0.35

chr8_-_19437095 0.35 ENSDART00000162010
zgc:92140
chr22_-_6995444 0.35 ENSDART00000003422
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr21_-_37342215 0.35 ENSDART00000076483
zgc:77151
chr18_+_18417187 0.35 ENSDART00000080174
nedd4 binding protein 1
chr6_-_8009143 0.34 ENSDART00000151358
ral guanine nucleotide dissociation stimulator-like 3a
chr12_+_33818555 0.34 ENSDART00000085888
tripartite motif containing 8b
chr16_+_12726556 0.34

chr7_-_73628090 0.33 ENSDART00000123136
Histone H2B 1/2
chr17_+_43916865 0.33 ENSDART00000049503
pellino E3 ubiquitin protein ligase family member 2
chr7_-_51351777 0.33 ENSDART00000174111
NHS-like 2
chr5_+_30880165 0.32 ENSDART00000098197
ENSDARG00000035471
chr25_+_3381632 0.32 ENSDART00000157777
zgc:153293
chr12_+_19199002 0.32 ENSDART00000066389
transmembrane protein 184ba
chr23_-_34017830 0.32 ENSDART00000133223
ENSDARG00000070393
chr23_-_34018069 0.31 ENSDART00000133223
ENSDARG00000070393
chr1_-_54089140 0.31

chr7_-_73628049 0.30 ENSDART00000123136
Histone H2B 1/2
chr23_-_31883578 0.29 ENSDART00000139076
HBS1-like translational GTPase
chr5_+_20319434 0.29 ENSDART00000093185
LIM domain kinase 2
chr22_+_38322821 0.29 ENSDART00000104498
REST corepressor 3
chr23_-_10810264 0.29 ENSDART00000013768
eukaryotic translation initiation factor 4E family member 3
chr8_-_37072691 0.28 ENSDART00000004041
zgc:162200
chr11_-_2226711 0.28

chr16_+_51317682 0.28 ENSDART00000157736
high mobility group nucleosomal binding domain 2
chr19_+_7505348 0.28 ENSDART00000004622
splicing factor 3b, subunit 4
chr14_+_6655894 0.28 ENSDART00000148394
heterogeneous nuclear ribonucleoprotein A/Ba
chr20_-_8847351 0.28 ENSDART00000141375
ENSDARG00000091901
chr25_-_413809 0.27

chr5_-_12586284 0.26 ENSDART00000051664
yippee-like 1
chr13_-_5128884 0.26 ENSDART00000110610
si:dkey-78p8.1
chr14_+_6655541 0.26 ENSDART00000148447
heterogeneous nuclear ribonucleoprotein A/Ba
chr17_+_21797517 0.25 ENSDART00000079011
IKAROS family zinc finger 5
chr21_-_40759658 0.25 ENSDART00000075808
amyloid beta (A4) precursor protein-binding, family B, member 3
chr22_-_7976568 0.25 ENSDART00000162028
sc:d217
chr24_-_26224123 0.25 ENSDART00000080039
leucine rich repeat containing 31
chr17_+_30529610 0.25 ENSDART00000154385
NHS-like 1a
chr19_+_40439831 0.24 ENSDART00000123647
splicing factor proline/glutamine-rich
chr14_-_32755624 0.24 ENSDART00000074720
discs, large homolog 3 (Drosophila)
chr5_-_37281096 0.24 ENSDART00000084819
Rho GTPase activating protein 35b
chr11_+_26366532 0.24 ENSDART00000159505
dynein, light chain, roadblock-type 1
chr17_-_7377094 0.24

chr23_-_3816422 0.24 ENSDART00000132205
high mobility group AT-hook 1a
chr12_-_19998765 0.24 ENSDART00000112768
UBA-like domain containing 1a
chr23_-_17502717 0.24

chr11_+_44962456 0.23 ENSDART00000172792
si:ch73-100l22.3
chr16_+_9835124 0.23 ENSDART00000020859
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b
chr25_-_34619603 0.23 ENSDART00000114767
ENSDARG00000076129
chr15_+_12497915 0.22 ENSDART00000168997
transmembrane protease, serine 4a
chr12_+_33818414 0.22 ENSDART00000085888
tripartite motif containing 8b
chr20_+_13885812 0.21 ENSDART00000142999
lysophosphatidylglycerol acyltransferase 1
chr17_-_45395144 0.21 ENSDART00000132969
zinc finger protein 106a
chr20_-_7079663 0.21 ENSDART00000040793
sirtuin 5
chr21_-_40759739 0.21 ENSDART00000075808
amyloid beta (A4) precursor protein-binding, family B, member 3
chr18_+_16726839 0.21 ENSDART00000166849
eukaryotic translation initiation factor 4, gamma 2b
chr16_-_16329761 0.21 ENSDART00000111912
RNA binding motif protein 12B
chr20_-_7079708 0.20 ENSDART00000040793
sirtuin 5
chr8_+_54034431 0.20 ENSDART00000170712
ENSDART00000164153
bromodomain and PHD finger containing 1
chr16_+_42567668 0.20 ENSDART00000166640
si:ch211-215k15.5
chr10_-_1669268 0.20 ENSDART00000125188
serine/arginine-rich splicing factor 9
chr9_-_55250643 0.20 ENSDART00000085693
glycoprotein M6Bb
chr19_-_30265997 0.20 ENSDART00000024292
taxilin alpha
chr6_-_8009055 0.20 ENSDART00000151358
ral guanine nucleotide dissociation stimulator-like 3a
chr23_-_29897606 0.20 ENSDART00000020616
zgc:194189
chr25_+_28380674 0.20 ENSDART00000067072
nuclear transcription factor Y, beta b
chr5_+_41463969 0.19 ENSDART00000035235
si:ch211-202a12.4
chr9_-_34145854 0.19

chr4_+_90885 0.19 ENSDART00000169805
epidermal growth factor receptor pathway substrate 8
chr1_+_30840735 0.19 ENSDART00000075286
solute carrier family 2 (facilitated glucose transporter), member 15b
chr12_+_2769741 0.19 ENSDART00000178262
MMS19 homolog, cytosolic iron-sulfur assembly component
chr12_-_5153412 0.19 ENSDART00000160037
FRA10A associated CGG repeat 1
chr6_-_53333532 0.18 ENSDART00000172465
guanine nucleotide binding protein (G protein), beta polypeptide 1b
chr20_-_25731057 0.18

chr21_-_35806609 0.18 ENSDART00000172245
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr16_-_33151504 0.17 ENSDART00000145055
proline-rich nuclear receptor coactivator 2
chr6_+_21896033 0.17 ENSDART00000163394
diacylglycerol kinase, epsilon
chr18_-_36291663 0.17

chr8_-_20830316 0.17 ENSDART00000147267
si:ch211-133l5.8
chr25_-_3377472 0.17 ENSDART00000173269
protein kinase cAMP-dependent type II regulatory subunit beta
chr16_+_26858600 0.17 ENSDART00000138496
RAD54 homolog B (S. cerevisiae)
chr8_+_4747546 0.16 ENSDART00000045533
transmembrane protein 127
chr9_+_34623833 0.16 ENSDART00000175455
si:ch211-269e2.1
chr2_-_33693243 0.16 ENSDART00000141192
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr23_+_35984969 0.16 ENSDART00000130260
homeobox C10a
chr2_+_38019291 0.16 ENSDART00000139564
DDB1 and CUL4 associated factor 8
chr12_+_19198701 0.16 ENSDART00000100075
transmembrane protein 184ba
chr10_+_32114762 0.16 ENSDART00000175047
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) a
chr7_-_41232765 0.16 ENSDART00000173577
ENSDARG00000105669
chr5_-_22098977 0.15 ENSDART00000011699
non-POU domain containing, octamer-binding
chr14_-_17270741 0.15 ENSDART00000161355
ENSDART00000168959
ring finger protein 4
chr12_+_26970745 0.15 ENSDART00000153426
Snf2-related CREBBP activator protein
chr3_+_34856462 0.15 ENSDART00000121981
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr22_+_30386668 0.14 ENSDART00000059923
max interactor 1, dimerization protein
chr12_-_28732946 0.14 ENSDART00000153200
si:ch211-194k22.8
chr2_-_23310316 0.14 ENSDART00000146014
Sin3A-associated protein b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0032024 positive regulation of peptide secretion(GO:0002793) positive regulation of insulin secretion(GO:0032024) positive regulation of hormone secretion(GO:0046887) positive regulation of peptide hormone secretion(GO:0090277)
0.2 1.2 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 2.0 GO:0000729 DNA double-strand break processing(GO:0000729)
0.2 0.7 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.2 0.6 GO:0010482 keratinocyte development(GO:0003334) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.2 4.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.1 2.8 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 0.7 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 1.3 GO:0006337 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.1 0.4 GO:0036047 regulation of ketone biosynthetic process(GO:0010566) protein demalonylation(GO:0036046) peptidyl-lysine demalonylation(GO:0036047) protein desuccinylation(GO:0036048) peptidyl-lysine desuccinylation(GO:0036049) protein deglutarylation(GO:0061698)
0.1 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.3 GO:0071908 determination of intestine left/right asymmetry(GO:0071908)
0.1 0.3 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.1 0.2 GO:0061511 centriole elongation(GO:0061511)
0.1 0.2 GO:0051580 neurotransmitter uptake(GO:0001504) regulation of neurotransmitter uptake(GO:0051580) neurotransmitter reuptake(GO:0098810)
0.1 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.2 GO:0021547 midbrain-hindbrain boundary initiation(GO:0021547)
0.1 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.2 GO:0051660 neuroblast proliferation(GO:0007405) establishment of centrosome localization(GO:0051660)
0.0 0.2 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.0 0.9 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 2.0 GO:0050821 protein stabilization(GO:0050821)
0.0 0.8 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) negative regulation of proteasomal protein catabolic process(GO:1901799) negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051)
0.0 0.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.7 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:1902946 protein localization to early endosome(GO:1902946)
0.0 0.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.0 GO:0008643 carbohydrate transport(GO:0008643)
0.0 0.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.1 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.1 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.6 GO:0007416 synapse assembly(GO:0007416)
0.0 0.0 GO:0016446 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.9 GO:0071599 otic vesicle development(GO:0071599)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.9 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.5 GO:0051453 regulation of intracellular pH(GO:0051453)
0.0 0.5 GO:0070304 positive regulation of stress-activated MAPK cascade(GO:0032874) positive regulation of stress-activated protein kinase signaling cascade(GO:0070304)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 2.8 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1 1.1 GO:0071564 npBAF complex(GO:0071564)
0.1 0.2 GO:0097361 CIA complex(GO:0097361)
0.1 2.0 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.8 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.7 GO:0000177 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.5 GO:0016605 PML body(GO:0016605)
0.0 0.6 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 5.5 GO:0005912 adherens junction(GO:0005912)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.5 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 1.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.9 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 1.5 GO:0016607 nuclear speck(GO:0016607)
0.0 0.5 GO:0016459 myosin complex(GO:0016459)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0010997 anaphase-promoting complex binding(GO:0010997) ubiquitin ligase activator activity(GO:1990757)
0.2 0.8 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.2 0.6 GO:0045545 syndecan binding(GO:0045545)
0.1 2.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.6 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.4 GO:0036054 protein-malonyllysine demalonylase activity(GO:0036054) protein-succinyllysine desuccinylase activity(GO:0036055) protein-glutaryllysine deglutarylase activity(GO:0061697)
0.1 0.4 GO:0005165 nerve growth factor receptor binding(GO:0005163) neurotrophin receptor binding(GO:0005165)
0.1 4.5 GO:0045296 cadherin binding(GO:0045296)
0.1 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.6 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 1.0 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 0.4 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 1.2 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.3 GO:0034452 dynactin binding(GO:0034452)
0.0 0.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0061608 nuclear import signal receptor activity(GO:0061608)
0.0 0.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 0.0 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 2.4 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 2.8 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.1 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 1.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.0 GO:0032135 DNA insertion or deletion binding(GO:0032135)
0.0 0.1 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 0.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.2 4.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.2 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 0.8 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.2 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm