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Results for sox8a+sox8b

Z-value: 0.38

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Transcription factors associated with sox8a+sox8b

Gene Symbol Gene ID Gene Info
sox8b
ENSDARG00000037782 SRY-box transcription factor 8b
sox8a
ENSDARG00000105301 SRY-box transcription factor 8a

Activity profile of sox8a+sox8b motif

Sorted Z-values of sox8a+sox8b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of sox8a+sox8b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr15_-_12484651 0.73 ENSDART00000162258
BX901957.1
ENSDARG00000098363
chr17_+_2373108 0.72 ENSDART00000156843
si:dkey-248g15.3
si:dkey-248g15.3
chr24_-_21778717 0.58 ENSDART00000131944
tagln3b
transgelin 3b
chr3_-_27516974 0.55 ENSDART00000151675
si:ch211-157c3.4
si:ch211-157c3.4
chr23_-_35595271 0.51 ENSDART00000164616
tuba1c
tubulin, alpha 1c
chr14_+_38445969 0.50 ENSDART00000164440
si:ch211-195b11.3
si:ch211-195b11.3
chr5_-_6004819 0.46 ENSDART00000099570
tnks1bp1
tankyrase 1 binding protein 1
chr15_+_28435937 0.45 ENSDART00000142298
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr25_+_24520476 0.42

chr2_-_24898678 0.41 ENSDART00000145145
cnn2
calponin 2
chr13_+_33151628 0.40 ENSDART00000135200
ccdc28b
coiled-coil domain containing 28B
chr11_-_18027225 0.39

chr17_-_32913432 0.37 ENSDART00000077476
prox1a
prospero homeobox 1a
chr3_-_6922655 0.36

chr2_+_10148323 0.33 ENSDART00000158214
tsen15
TSEN15 tRNA splicing endonuclease subunit
chr3_-_27517052 0.32 ENSDART00000151625
si:ch211-157c3.4
si:ch211-157c3.4
chr24_-_41356844 0.30 ENSDART00000121592
ENSDART00000019975
ENSDART00000166034
acvr2b
activin A receptor, type IIB
chr21_+_43674754 0.30 ENSDART00000136025
tmlhe
trimethyllysine hydroxylase, epsilon
chr14_+_6239755 0.28 ENSDART00000097214
adam19b
ADAM metallopeptidase domain 19b
chr11_-_37730181 0.28 ENSDART00000102870
slc41a1
solute carrier family 41 (magnesium transporter), member 1
chr5_+_69036145 0.26 ENSDART00000174403
fsd1l
fibronectin type III and SPRY domain containing 1-like
chr9_-_43736549 0.25 ENSDART00000140526
znf385b
zinc finger protein 385B
chr13_-_8560564 0.25 ENSDART00000144553
plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr7_-_50137683 0.24 ENSDART00000083346
hypk
huntingtin interacting protein K
chr7_+_64897785 0.22 ENSDART00000113602
ENSDART00000167822
ipo7
importin 7
chr11_-_29891067 0.22 ENSDART00000172106
scml2
sex comb on midleg-like 2 (Drosophila)
chr19_-_27864181 0.22 ENSDART00000079251
vars2
valyl-tRNA synthetase 2, mitochondrial (putative)
chr20_+_54525614 0.21 ENSDART00000160409
arf6a
ADP-ribosylation factor 6a
chr17_+_24668907 0.21 ENSDART00000034263
ENSDART00000135794
sepn1
selenoprotein N, 1
chr7_-_18295101 0.20 ENSDART00000173969
rgs12a
regulator of G protein signaling 12a
chr6_+_7165326 0.20 ENSDART00000065500
abcc4
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr3_+_41584507 0.20 ENSDART00000154401
chst12a
carbohydrate (chondroitin 4) sulfotransferase 12a
chr22_-_38635149 0.20 ENSDART00000098330
nppc
natriuretic peptide C
chr2_+_10148394 0.19 ENSDART00000158214
tsen15
TSEN15 tRNA splicing endonuclease subunit
chr4_+_22576862 0.19 ENSDART00000077707
llph
LLP homolog, long-term synaptic facilitation (Aplysia)
chr7_-_52574822 0.18 ENSDART00000172951
map1aa
microtubule-associated protein 1Aa
chr8_+_46378250 0.17 ENSDART00000129661
ENSDART00000084081
ogg1
8-oxoguanine DNA glycosylase
chr1_-_9256864 0.17 ENSDART00000041849
tmem8a
transmembrane protein 8A
chr16_-_25691856 0.17 ENSDART00000077447
ENSDART00000131528
zgc:110410
zgc:110410
chr20_-_54669179 0.16

chr1_+_5948527 0.16 ENSDART00000138919
ube2f
ubiquitin-conjugating enzyme E2F (putative)
chr16_+_25180444 0.15 ENSDART00000157346
ENSDART00000155032
si:ch211-261d7.3
si:ch211-261d7.3
chr7_-_38521262 0.15 ENSDART00000157416
si:dkey-23n7.10
si:dkey-23n7.10
chr8_-_46378116 0.15 ENSDART00000136602
qars
glutaminyl-tRNA synthetase
chr1_+_37643126 0.14 ENSDART00000075086
cep44
centrosomal protein 44
chr17_+_14776302 0.14 ENSDART00000154229
RTRAF
zgc:56576
chr19_-_27284726 0.14 ENSDART00000089699
prrt1
proline-rich transmembrane protein 1
chr10_+_16009487 0.14 ENSDART00000136709
apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr21_-_43332911 0.13 ENSDART00000114955
sowahaa
sosondowah ankyrin repeat domain family member Aa
chr6_-_37765778 0.13 ENSDART00000149068
nipa2
non imprinted in Prader-Willi/Angelman syndrome 2 (human)
chr14_-_25154966 0.12 ENSDART00000148652
slc26a2
solute carrier family 26 (anion exchanger), member 2
chr10_+_9762039 0.12

chr19_-_27864288 0.11 ENSDART00000079251
vars2
valyl-tRNA synthetase 2, mitochondrial (putative)
chr5_+_18797669 0.11 ENSDART00000165119
rusc2
RUN and SH3 domain containing 2
chr6_+_13273286 0.10 ENSDART00000032331
gmppab
GDP-mannose pyrophosphorylase Ab
chr9_+_17415990 0.09 ENSDART00000112884
kbtbd7
kelch repeat and BTB (POZ) domain containing 7
chr12_+_30591482 0.09 ENSDART00000133869
kcnk1a
potassium channel, subfamily K, member 1a
chr10_-_14587464 0.08 ENSDART00000057865
ier3ip1
immediate early response 3 interacting protein 1
chr21_+_37668334 0.07 ENSDART00000143621
nsd1b
nuclear receptor binding SET domain protein 1b
chr18_-_20880226 0.07 ENSDART00000090079
synm
synemin, intermediate filament protein
chr8_+_20592099 0.07 ENSDART00000160421
nfic
nuclear factor I/C
chr9_-_3028101 0.07 ENSDART00000144046
rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr21_-_22441376 0.06

chr13_-_8560620 0.06 ENSDART00000144553
plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr2_+_25114775 0.06 ENSDART00000078854
mpv17l2
MPV17 mitochondrial membrane protein-like 2
chr17_+_11961595 0.06

chr5_+_54642472 0.05 ENSDART00000131060
pcsk5a
proprotein convertase subtilisin/kexin type 5a
chr15_+_28435875 0.04 ENSDART00000168453
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr14_+_49875056 0.04 ENSDART00000167810
zgc:154054
zgc:154054
chr7_+_22710714 0.04 ENSDART00000122449
ccnb3
cyclin B3
chr20_+_30676086 0.03 ENSDART00000131422
ENSDART00000010494
fgfr1op
FGFR1 oncogene partner
chr6_+_49927433 0.03 ENSDART00000018523
ahcy
adenosylhomocysteinase
chr2_+_42923652 0.03 ENSDART00000168318
BX005083.1
ENSDARG00000097562
chr4_+_6825027 0.02 ENSDART00000165179
dock4b
dedicator of cytokinesis 4b
chr19_-_12032026 0.02 ENSDART00000024861
ENSDART00000110513
ENSDART00000163478
cpsf1
cleavage and polyadenylation specific factor 1
chr20_+_26037296 0.01 ENSDART00000141265
znf106b
zinc finger protein 106b
chr11_+_39694880 0.01 ENSDART00000024304
per3
period circadian clock 3
chr10_+_5267746 0.01 ENSDART00000114491
ror2
receptor tyrosine kinase-like orphan receptor 2
chr20_+_31371853 0.01

chr20_-_29602821 0.01 ENSDART00000148278
klf11a
Kruppel-like factor 11a
chr8_-_14014576 0.00 ENSDART00000135811
atp2b3a
ATPase, Ca++ transporting, plasma membrane 3a
chr16_+_50355723 0.00 ENSDART00000166664
ENSDARG00000102916
ENSDARG00000102916

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097484 dendrite extension(GO:0097484)
0.0 0.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.3 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.5 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.4 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.4 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.5 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.1 GO:0061668 mitochondrial ribosome assembly(GO:0061668)
0.0 0.2 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.3 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.1 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.2 GO:0031114 regulation of microtubule depolymerization(GO:0031114)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.3 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.1 GO:0008905 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters