ISMARA results: sp1

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Results for sp1

Z-value: 4.19

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Transcription factors associated with sp1

Gene Symbol	Gene ID	Gene Info
sp1 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000088347	sp1 transcription factor

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
sp1	dr10_dc_chr11_-_28193_28230	-0.69	2.9e-03	Click!

Activity profile of sp1 motif

Sorted Z-values of sp1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of sp1

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr20_+_33391554 Show fit	14.47	ENSDART00000024104	mycn NCBI UniProt ZFIN ENSEMBL Google Show fit	MYCN proto-oncogene, bHLH transcription factor
chr13_+_11913290 Show fit	12.65	ENSDART00000079398	gng2 NCBI UniProt ZFIN ENSEMBL Google Show fit	guanine nucleotide binding protein (G protein), gamma 2
chr16_-_46799406 Show fit	11.61	ENSDART00000115244	MEX3A NCBI UniProt ZFIN ENSEMBL Google Show fit	mex-3 RNA binding family member A
chr5_-_43896815 Show fit	10.95	ENSDART00000110076	gas1a NCBI UniProt ZFIN ENSEMBL Google Show fit	growth arrest-specific 1a
chr18_-_41660821 Show fit	10.64	ENSDART00000024087	fzd9b NCBI UniProt ZFIN ENSEMBL Google Show fit	frizzled class receptor 9b
chr3_+_22412059 Show fit	10.39
chr19_-_32214978 Show fit	10.04	ENSDART00000103640	hey1 NCBI UniProt ZFIN ENSEMBL Google Show fit	hes-related family bHLH transcription factor with YRPW motif 1
chr16_+_46327528 Show fit	9.80	ENSDART00000040769	nr2f5 NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear receptor subfamily 2, group F, member 5
chr10_+_4094568 Show fit	9.71	ENSDART00000114533	mn1a NCBI UniProt ZFIN ENSEMBL Google Show fit	meningioma 1a
chr22_+_13862110 Show fit	9.46	ENSDART00000105711	sh3bp4a NCBI UniProt ZFIN ENSEMBL Google Show fit	SH3-domain binding protein 4a
chr3_+_16115708 Show fit	9.43	ENSDART00000122519	st8sia6 NCBI UniProt ZFIN ENSEMBL Google Show fit	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr16_-_7525980 Show fit	9.27	ENSDART00000017445	prdm1a NCBI UniProt ZFIN ENSEMBL Google Show fit	PR domain containing 1a, with ZNF domain
chr6_-_39315024 Show fit	9.13	ENSDART00000012644	krt4 NCBI UniProt ZFIN ENSEMBL Google Show fit	keratin 4
chr2_+_11973282 Show fit	9.03	ENSDART00000057268	greb1l NCBI UniProt ZFIN ENSEMBL Google Show fit	growth regulation by estrogen in breast cancer-like
chr5_+_4372660 Show fit	8.54	ENSDART00000067599	angptl2a NCBI UniProt ZFIN ENSEMBL Google Show fit	angiopoietin-like 2a
chr3_+_32394653 Show fit	8.43	ENSDART00000150897	si:ch73-367p23.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-367p23.2
chr24_-_38068071 Show fit	8.28	ENSDART00000041805	metrn NCBI UniProt ZFIN ENSEMBL Google Show fit	meteorin, glial cell differentiation regulator
chr7_+_34417030 Show fit	8.23	ENSDART00000108473	plekhg4 NCBI UniProt ZFIN ENSEMBL Google Show fit	pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr23_+_10412852 Show fit	8.18	ENSDART00000142595	krt18 NCBI UniProt ZFIN ENSEMBL Google Show fit	keratin 18
chr12_-_26760324 Show fit	8.14	ENSDART00000047724	zeb1b NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger E-box binding homeobox 1b
chr18_-_11216447 Show fit	8.14	ENSDART00000040500	tspan9a NCBI UniProt ZFIN ENSEMBL Google Show fit	tetraspanin 9a
chr22_+_10622013 Show fit	8.08	ENSDART00000145459	rassf1 NCBI UniProt ZFIN ENSEMBL Google Show fit	Ras association (RalGDS/AF-6) domain family 1
chr5_-_43896757 Show fit	8.01	ENSDART00000110076	gas1a NCBI UniProt ZFIN ENSEMBL Google Show fit	growth arrest-specific 1a
chr1_-_50066633 Show fit	8.01
chr11_+_25022419 Show fit	7.99
chr5_+_6054781 Show fit	7.98	ENSDART00000060532	zgc:110796 NCBI UniProt ZFIN ENSEMBL Google Show fit	zgc:110796
chr15_+_19902697 Show fit	7.87	ENSDART00000101204	alcamb NCBI UniProt ZFIN ENSEMBL Google Show fit	activated leukocyte cell adhesion molecule b
chr8_+_1122000 Show fit	7.74	ENSDART00000127252	slc35d2 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
chr22_-_35967525 Show fit	7.72	ENSDART00000176971	CABZ01037120.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ENSDARG00000106725
chr11_-_471166 Show fit	7.61	ENSDART00000154888	cnbpb NCBI UniProt ZFIN ENSEMBL Google Show fit	CCHC-type zinc finger, nucleic acid binding protein b
chr21_+_25199691 Show fit	7.54	ENSDART00000168140 ENSDART00000112783	tmem45b NCBI UniProt ZFIN ENSEMBL Google Show fit	transmembrane protein 45B
chr7_+_21455138 Show fit	7.51	ENSDART00000173992	kdm6ba NCBI UniProt ZFIN ENSEMBL Google Show fit	lysine (K)-specific demethylase 6B, a
chr18_-_49324015 Show fit	7.48	ENSDART00000098419	sb:cb81 NCBI UniProt ZFIN ENSEMBL Google Show fit	sb:cb81
chr9_-_24431684 Show fit	7.43	ENSDART00000039399	cavin2a NCBI UniProt ZFIN ENSEMBL Google Show fit	caveolae associated protein 2a
chr13_-_33696425 Show fit	7.37	ENSDART00000143703	flrt3 NCBI UniProt ZFIN ENSEMBL Google Show fit	fibronectin leucine rich transmembrane 3
chr11_+_23522743 Show fit	7.33	ENSDART00000121874	nfasca NCBI UniProt ZFIN ENSEMBL Google Show fit	neurofascin homolog (chicken) a
chr13_+_11912981 Show fit	7.27	ENSDART00000158244	gng2 NCBI UniProt ZFIN ENSEMBL Google Show fit	guanine nucleotide binding protein (G protein), gamma 2
chr1_-_18110990 Show fit	7.25	ENSDART00000020970	pgm2 NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphoglucomutase 2
chr11_-_32461160 Show fit	7.21	ENSDART00000155592	pcdh17 NCBI UniProt ZFIN ENSEMBL Google Show fit	protocadherin 17
chr25_-_325847 Show fit	7.15	ENSDART00000059514	prickle1a NCBI UniProt ZFIN ENSEMBL Google Show fit	prickle homolog 1a
chr20_-_25063937 Show fit	7.08	ENSDART00000159122	epha7 NCBI UniProt ZFIN ENSEMBL Google Show fit	eph receptor A7
chr8_+_20125687 Show fit	7.06	ENSDART00000124809	acsbg2 NCBI UniProt ZFIN ENSEMBL Google Show fit	acyl-CoA synthetase bubblegum family member 2
chr19_+_48582114 Show fit	7.03	ENSDART00000157424	CU693379.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ENSDARG00000098777
chr3_-_53304694 Show fit	6.96	ENSDART00000073930	notch3 NCBI UniProt ZFIN ENSEMBL Google Show fit	notch 3
chr7_-_23965038 Show fit	6.93	ENSDART00000010124	slc7a8a NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 7 (amino acid transporter light chain, L system), member 8a
chr8_-_53508979 Show fit	6.86	ENSDART00000158789	chdh NCBI UniProt ZFIN ENSEMBL Google Show fit	choline dehydrogenase
chr17_-_124685 Show fit	6.82	ENSDART00000158825	actc1b NCBI UniProt ZFIN ENSEMBL Google Show fit	actin, alpha, cardiac muscle 1b
chr15_+_46114986 Show fit	6.80	ENSDART00000156366	si:ch1073-340i21.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch1073-340i21.3
chr10_-_33678206 Show fit	6.80	ENSDART00000128049	hunk NCBI UniProt ZFIN ENSEMBL Google Show fit	hormonally up-regulated Neu-associated kinase
chr19_-_15951003 Show fit	6.74	ENSDART00000133059	cited4a NCBI UniProt ZFIN ENSEMBL Google Show fit	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
chr3_-_62143464 Show fit	6.73	ENSDART00000155853	gprc5ba NCBI UniProt ZFIN ENSEMBL Google Show fit	G protein-coupled receptor, class C, group 5, member Ba
chr22_+_30234718 Show fit	6.70	ENSDART00000172496	add3a NCBI UniProt ZFIN ENSEMBL Google Show fit	adducin 3 (gamma) a
chr19_+_42491631 Show fit	6.66	ENSDART00000150949	nfyc NCBI UniProt ZFIN ENSEMBL Google Show fit	nuclear transcription factor Y, gamma
chr5_-_7134405 Show fit	6.65	ENSDART00000177935	bmpr1ba NCBI UniProt ZFIN ENSEMBL Google Show fit	bone morphogenetic protein receptor, type IBa
chr1_-_44888989 Show fit	6.65	ENSDART00000135089	atf7ip NCBI UniProt ZFIN ENSEMBL Google Show fit	activating transcription factor 7 interacting protein
chr20_-_54192057 Show fit	6.56	ENSDART00000023550	hsp90aa1.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2
chr16_-_24220413 Show fit	6.55	ENSDART00000103176	bcam NCBI UniProt ZFIN ENSEMBL Google Show fit	basal cell adhesion molecule (Lutheran blood group)
chr23_-_24468191 Show fit	6.54	ENSDART00000044918	epha2b NCBI UniProt ZFIN ENSEMBL Google Show fit	eph receptor A2 b
chr7_-_50827308 Show fit	6.52	ENSDART00000121574	col4a6 NCBI UniProt ZFIN ENSEMBL Google Show fit	collagen, type IV, alpha 6
chr15_-_11257445 Show fit	6.50
chr20_+_30917073 Show fit	6.48
chr13_-_33574216 Show fit	6.44	ENSDART00000065435	cst3 NCBI UniProt ZFIN ENSEMBL Google Show fit	cystatin C (amyloid angiopathy and cerebral hemorrhage)
chr11_-_19612693 Show fit	6.44	ENSDART00000037894	namptb NCBI UniProt ZFIN ENSEMBL Google Show fit	nicotinamide phosphoribosyltransferase b
chr23_-_45250886 Show fit	6.44	ENSDART00000163367	ENSDARG00000103727 NCBI UniProt ZFIN ENSEMBL Google Show fit	ENSDARG00000103727
chr10_-_32580145 Show fit	6.39	ENSDART00000137608	dgat2 NCBI UniProt ZFIN ENSEMBL Google Show fit	diacylglycerol O-acyltransferase 2
chr22_+_11726312 Show fit	6.35	ENSDART00000155366	krt96 NCBI UniProt ZFIN ENSEMBL Google Show fit	keratin 96
chr8_+_21163236 Show fit	6.32	ENSDART00000091307	col2a1a NCBI UniProt ZFIN ENSEMBL Google Show fit	collagen, type II, alpha 1a
chr10_-_42032702 Show fit	6.24
chr12_+_689413 Show fit	6.21	ENSDART00000174804	abcc3 NCBI UniProt ZFIN ENSEMBL Google Show fit	ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr3_+_28450576 Show fit	6.17	ENSDART00000150893	sept12 NCBI UniProt ZFIN ENSEMBL Google Show fit	septin 12
chr23_+_36832325 Show fit	6.13
chr9_+_36051713 Show fit	6.04	ENSDART00000134447	rcan1a NCBI UniProt ZFIN ENSEMBL Google Show fit	regulator of calcineurin 1a
chr4_-_25075693 Show fit	6.01	ENSDART00000025153	gata3 NCBI UniProt ZFIN ENSEMBL Google Show fit	GATA binding protein 3
chr8_-_14142049 Show fit	5.98	ENSDART00000126432	rhoaa NCBI UniProt ZFIN ENSEMBL Google Show fit	ras homolog gene family, member Aa
chr1_-_40536800 Show fit	5.98	ENSDART00000134739	rgs12b NCBI UniProt ZFIN ENSEMBL Google Show fit	regulator of G protein signaling 12b
chr9_-_48098629 Show fit	5.95
chr14_+_4810147 Show fit	5.94	ENSDART00000114678	nanos1 NCBI UniProt ZFIN ENSEMBL Google Show fit	nanos homolog 1
chr5_-_4091643 Show fit	5.93	ENSDART00000067594	cst14b.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cystatin 14b, tandem duplicate 1
chr22_+_26543146 Show fit	5.91
chr24_-_1155215 Show fit	5.91	ENSDART00000177356	itgb1a NCBI UniProt ZFIN ENSEMBL Google Show fit	integrin, beta 1a
chr8_+_584353 Show fit	5.91	ENSDART00000048498	CABZ01049925.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ENSDARG00000079790
chr6_+_49096966 Show fit	5.88	ENSDART00000141042 ENSDART00000143369	slc25a22 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr8_+_10267246 Show fit	5.88	ENSDART00000159312 ENSDART00000160766	pim1 NCBI UniProt ZFIN ENSEMBL Google Show fit	Pim-1 proto-oncogene, serine/threonine kinase
chr1_-_674449 Show fit	5.86	ENSDART00000160564	cyyr1 NCBI UniProt ZFIN ENSEMBL Google Show fit	cysteine/tyrosine-rich 1
chr4_-_876235 Show fit	5.86
chr5_+_68410884 Show fit	5.86	ENSDART00000153691	CU928129.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ENSDARG00000097815
chr13_-_22877318 Show fit	5.86	ENSDART00000057638 ENSDART00000171778	hk1 NCBI UniProt ZFIN ENSEMBL Google Show fit	hexokinase 1
chr10_-_32580373 Show fit	5.84	ENSDART00000066793	dgat2 NCBI UniProt ZFIN ENSEMBL Google Show fit	diacylglycerol O-acyltransferase 2
chr19_-_11113032 Show fit	5.82	ENSDART00000027598	tpm3 NCBI UniProt ZFIN ENSEMBL Google Show fit	tropomyosin 3
chr16_+_4825019 Show fit	5.80	ENSDART00000167665	LIN28A NCBI UniProt ZFIN ENSEMBL Google Show fit	lin-28 homolog A
chr23_-_2573949 Show fit	5.72	ENSDART00000123322	snai1b NCBI UniProt ZFIN ENSEMBL Google Show fit	snail family zinc finger 1b
chr3_+_5665300 Show fit	5.72	ENSDART00000101807	si:ch211-106h11.3 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-106h11.3
chr21_+_5693372 Show fit	5.70	ENSDART00000020603	ccng2 NCBI UniProt ZFIN ENSEMBL Google Show fit	cyclin G2
chr16_+_17705704 Show fit	5.64
chr21_+_25729090 Show fit	5.62	ENSDART00000021664	cldnb NCBI UniProt ZFIN ENSEMBL Google Show fit	claudin b
chr5_-_7666964 Show fit	5.59	ENSDART00000167643	slc1a3a NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 1 (glial high affinity glutamate transporter), member 3a
chr3_-_6078015 Show fit	5.58	ENSDART00000165715	BX284638.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ENSDARG00000098850
chr21_-_32403403 Show fit	5.58	ENSDART00000076974	gfpt2 NCBI UniProt ZFIN ENSEMBL Google Show fit	glutamine-fructose-6-phosphate transaminase 2
chr25_+_33527870 Show fit	5.56	ENSDART00000011967	anxa2a NCBI UniProt ZFIN ENSEMBL Google Show fit	annexin A2a
chr10_+_15819127 Show fit	5.53	ENSDART00000140511	apba1b NCBI UniProt ZFIN ENSEMBL Google Show fit	amyloid beta (A4) precursor protein-binding, family A, member 1b
chr5_-_18548689 Show fit	5.53	ENSDART00000137802	fam214b NCBI UniProt ZFIN ENSEMBL Google Show fit	family with sequence similarity 214, member B
chr1_-_31123999 Show fit	5.51	ENSDART00000152493	nt5c2b NCBI UniProt ZFIN ENSEMBL Google Show fit	5'-nucleotidase, cytosolic IIb
chr5_-_36647498 Show fit	5.49	ENSDART00000112312	lrch2 NCBI UniProt ZFIN ENSEMBL Google Show fit	leucine-rich repeats and calponin homology (CH) domain containing 2
chr1_+_29054033 Show fit	5.48	ENSDART00000054066	zic2b NCBI UniProt ZFIN ENSEMBL Google Show fit	zic family member 2 (odd-paired homolog, Drosophila) b
chr6_-_2294751 Show fit	5.42	ENSDART00000165223	pbx1b NCBI UniProt ZFIN ENSEMBL Google Show fit	pre-B-cell leukemia homeobox 1b
chr20_+_17840364 Show fit	5.41	ENSDART00000024627	cdh2 NCBI UniProt ZFIN ENSEMBL Google Show fit	cadherin 2, type 1, N-cadherin (neuronal)
chr22_-_15567180 Show fit	5.41	ENSDART00000123125	tpm4a NCBI UniProt ZFIN ENSEMBL Google Show fit	tropomyosin 4a
chr20_+_30894667 Show fit	5.36	ENSDART00000145066	nhsl1b NCBI UniProt ZFIN ENSEMBL Google Show fit	NHS-like 1b
chr20_+_26408687 Show fit	5.36
chr11_-_44724371 Show fit	5.34	ENSDART00000166501	cant1b NCBI UniProt ZFIN ENSEMBL Google Show fit	calcium activated nucleotidase 1b
chr17_+_45931793 Show fit	5.34	ENSDART00000155372	kif26ab NCBI UniProt ZFIN ENSEMBL Google Show fit	kinesin family member 26Ab
chr15_-_33669717 Show fit	5.34	ENSDART00000161151	stard13b NCBI UniProt ZFIN ENSEMBL Google Show fit	StAR-related lipid transfer (START) domain containing 13b
chr4_+_1750689 Show fit	5.31	ENSDART00000146779	slc38a2 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 38, member 2
chr9_-_9693163 Show fit	5.27	ENSDART00000018228	gsk3b NCBI UniProt ZFIN ENSEMBL Google Show fit	glycogen synthase kinase 3 beta
chr21_-_39013447 Show fit	5.26	ENSDART00000114885	aldh3a2b NCBI UniProt ZFIN ENSEMBL Google Show fit	aldehyde dehydrogenase 3 family, member A2b
chr16_-_32022177 Show fit	5.25	ENSDART00000139664	styk1 NCBI UniProt ZFIN ENSEMBL Google Show fit	serine/threonine/tyrosine kinase 1
chr1_-_50513873 Show fit	5.21	ENSDART00000137172	jag1a NCBI UniProt ZFIN ENSEMBL Google Show fit	jagged 1a
chr1_-_50831155 Show fit	5.19	ENSDART00000152719	spred2a NCBI UniProt ZFIN ENSEMBL Google Show fit	sprouty-related, EVH1 domain containing 2a
chr18_-_45750 Show fit	5.19	ENSDART00000148821	gatm NCBI UniProt ZFIN ENSEMBL Google Show fit	glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr5_-_19357961 Show fit	5.18	ENSDART00000088904 ENSDART00000163701	gltpa NCBI UniProt ZFIN ENSEMBL Google Show fit	glycolipid transfer protein a
chr5_-_40961381 Show fit	5.17
chr1_-_50513645 Show fit	5.17	ENSDART00000047851	jag1a NCBI UniProt ZFIN ENSEMBL Google Show fit	jagged 1a
chr16_-_42486580 Show fit	5.17	ENSDART00000148475	cspg5a NCBI UniProt ZFIN ENSEMBL Google Show fit	chondroitin sulfate proteoglycan 5a
chr10_-_28949111 Show fit	5.17	ENSDART00000030138	alcama NCBI UniProt ZFIN ENSEMBL Google Show fit	activated leukocyte cell adhesion molecule a
chr19_-_24971633 Show fit	5.16	ENSDART00000162801	polr3gla NCBI UniProt ZFIN ENSEMBL Google Show fit	polymerase (RNA) III (DNA directed) polypeptide G like a
chr19_+_12315359 Show fit	5.14	ENSDART00000149221	grhl2b NCBI UniProt ZFIN ENSEMBL Google Show fit	grainyhead-like transcription factor 2b
chr15_-_21901138 Show fit	5.13	ENSDART00000089953	sik2b NCBI UniProt ZFIN ENSEMBL Google Show fit	salt-inducible kinase 2b
chr23_+_44817648 Show fit	5.12	ENSDART00000143688	dlg4b NCBI UniProt ZFIN ENSEMBL Google Show fit	discs, large homolog 4b (Drosophila)
chr1_-_18695214 Show fit	5.08
chr2_-_39710140 Show fit	5.08	ENSDART00000147821	spsb4a NCBI UniProt ZFIN ENSEMBL Google Show fit	splA/ryanodine receptor domain and SOCS box containing 4a
chr23_-_7283514 Show fit	5.08	ENSDART00000156369	CR589876.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ENSDARG00000096997
chr8_+_47861033 Show fit	5.06	ENSDART00000147159	plod1a NCBI UniProt ZFIN ENSEMBL Google Show fit	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1a
chr19_-_7531709 Show fit	5.03	ENSDART00000104750	mllt11 NCBI UniProt ZFIN ENSEMBL Google Show fit	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11
chr13_+_22350043 Show fit	5.03	ENSDART00000136863	ldb3a NCBI UniProt ZFIN ENSEMBL Google Show fit	LIM domain binding 3a
chr14_-_6901415 Show fit	5.01	ENSDART00000167994 ENSDART00000166532	stox2b NCBI UniProt ZFIN ENSEMBL Google Show fit	storkhead box 2b
chr10_-_43815475 Show fit	5.00	ENSDART00000027392	mef2ca NCBI UniProt ZFIN ENSEMBL Google Show fit	myocyte enhancer factor 2ca
chr18_+_38307946 Show fit	5.00	ENSDART00000134247	lmo2 NCBI UniProt ZFIN ENSEMBL Google Show fit	LIM domain only 2 (rhombotin-like 1)
chr15_-_4154407 Show fit	4.98	ENSDART00000090624	lpar6a NCBI UniProt ZFIN ENSEMBL Google Show fit	lysophosphatidic acid receptor 6a
chr20_-_21773202 Show fit	4.97	ENSDART00000133286	si:ch211-207i1.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-207i1.2
chr21_-_36338514 Show fit	4.97	ENSDART00000157826	mpp1 NCBI UniProt ZFIN ENSEMBL Google Show fit	membrane protein, palmitoylated 1
chr17_+_15425559 Show fit	4.97	ENSDART00000026180	fabp7a NCBI UniProt ZFIN ENSEMBL Google Show fit	fatty acid binding protein 7, brain, a
chr6_+_39373026 Show fit	4.96	ENSDART00000157165	si:dkey-195m11.8 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-195m11.8
chr2_-_24275851 Show fit	4.96	ENSDART00000121885	tgfbr1a NCBI UniProt ZFIN ENSEMBL Google Show fit	transforming growth factor, beta receptor 1 a
chr2_-_43998886 Show fit	4.92	ENSDART00000146493	zeb1a NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger E-box binding homeobox 1a
chr16_+_42993841 Show fit	4.88	ENSDART00000156767	CR854827.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	ENSDARG00000097750
chr24_+_28364360 Show fit	4.86	ENSDART00000018037	arhgap29a NCBI UniProt ZFIN ENSEMBL Google Show fit	Rho GTPase activating protein 29a
chr10_+_10830549 Show fit	4.85	ENSDART00000101077 ENSDART00000139143	ptgdsa NCBI UniProt ZFIN ENSEMBL Google Show fit	prostaglandin D2 synthase a
chr11_-_42934175 Show fit	4.85	ENSDART00000172929	sptbn1 NCBI UniProt ZFIN ENSEMBL Google Show fit	spectrin, beta, non-erythrocytic 1
chr20_-_158899 Show fit	4.85	ENSDART00000131635	slc16a10 NCBI UniProt ZFIN ENSEMBL Google Show fit	solute carrier family 16 (aromatic amino acid transporter), member 10
chr7_+_73408688 Show fit	4.85	ENSDART00000159745	PCP4L1 NCBI UniProt ZFIN ENSEMBL Google Show fit	Purkinje cell protein 4 like 1
chr11_-_25693072 Show fit	4.81	ENSDART00000122011	kaznb NCBI UniProt ZFIN ENSEMBL Google Show fit	kazrin, periplakin interacting protein b
chr12_+_11042472 Show fit	4.79	ENSDART00000079336	raraa NCBI UniProt ZFIN ENSEMBL Google Show fit	retinoic acid receptor, alpha a
chr19_+_31046291 Show fit	4.79	ENSDART00000052124	fam49al NCBI UniProt ZFIN ENSEMBL Google Show fit	family with sequence similarity 49, member A-like
chr24_-_21114505 Show fit	4.69	ENSDART00000111025	boc NCBI UniProt ZFIN ENSEMBL Google Show fit	BOC cell adhesion associated, oncogene regulated
chr21_-_11554253 Show fit	4.67	ENSDART00000133443	cast NCBI UniProt ZFIN ENSEMBL Google Show fit	calpastatin
chr19_-_1905372 Show fit	4.63	ENSDART00000029646	rplp1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ribosomal protein, large, P1
chr15_-_9026081 Show fit	4.59	ENSDART00000126708	rhoub NCBI UniProt ZFIN ENSEMBL Google Show fit	ras homolog family member Ub
chr5_-_56984800 Show fit	4.59	ENSDART00000074290	mia NCBI UniProt ZFIN ENSEMBL Google Show fit	melanoma inhibitory activity
chr13_+_22173410 Show fit	4.58	ENSDART00000173405	usp54a NCBI UniProt ZFIN ENSEMBL Google Show fit	ubiquitin specific peptidase 54a
chr20_-_23184142 Show fit	4.57	ENSDART00000176282	CU693368.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	ENSDARG00000108718
chr7_-_64637419 Show fit	4.56	ENSDART00000020456	mmp15b NCBI UniProt ZFIN ENSEMBL Google Show fit	matrix metallopeptidase 15b
chr7_-_24093289 Show fit	4.56	ENSDART00000064789	txn NCBI UniProt ZFIN ENSEMBL Google Show fit	thioredoxin
chr19_-_5338129 Show fit	4.54	ENSDART00000081951	stx1b NCBI UniProt ZFIN ENSEMBL Google Show fit	syntaxin 1B
chr8_+_4641405 Show fit	4.54	ENSDART00000064197	cldn5a NCBI UniProt ZFIN ENSEMBL Google Show fit	claudin 5a
chr23_+_45020761 Show fit	4.53	ENSDART00000159104	atp1b2a NCBI UniProt ZFIN ENSEMBL Google Show fit	ATPase, Na+/K+ transporting, beta 2a polypeptide
chr18_+_26102262 Show fit	4.52	ENSDART00000164495	znf710a NCBI UniProt ZFIN ENSEMBL Google Show fit	zinc finger protein 710a
chr3_+_15656123 Show fit	4.52	ENSDART00000055834	phospho1 NCBI UniProt ZFIN ENSEMBL Google Show fit	phosphatase, orphan 1
chr14_-_40454194 Show fit	4.51	ENSDART00000166621	ef1 NCBI UniProt ZFIN ENSEMBL Google Show fit	E74-like factor 1 (ets domain transcription factor)
chr7_-_16346150 Show fit	4.48	ENSDART00000128488	e2f8 NCBI UniProt ZFIN ENSEMBL Google Show fit	E2F transcription factor 8
chr9_-_22140954 Show fit	4.48	ENSDART00000146528	lmo7a NCBI UniProt ZFIN ENSEMBL Google Show fit	LIM domain 7a
chr3_+_16115532 Show fit	4.47
chr19_-_617298 Show fit	4.47	ENSDART00000171387	cyp51 NCBI UniProt ZFIN ENSEMBL Google Show fit	cytochrome P450, family 51
chr5_-_39910235 Show fit	4.46	ENSDART00000146237 ENSDART00000163302	fsta NCBI UniProt ZFIN ENSEMBL Google Show fit	follistatin a
chr3_+_52901602 Show fit	4.45	ENSDART00000114343	brd4 NCBI UniProt ZFIN ENSEMBL Google Show fit	bromodomain containing 4
chr2_-_38242982 Show fit	4.43	ENSDART00000040357	acin1a NCBI UniProt ZFIN ENSEMBL Google Show fit	apoptotic chromatin condensation inducer 1a
chr1_-_416138 Show fit	4.42	ENSDART00000092524	rasa3 NCBI UniProt ZFIN ENSEMBL Google Show fit	RAS p21 protein activator 3
chr13_+_4276783 Show fit	4.39	ENSDART00000148280	prr18 NCBI UniProt ZFIN ENSEMBL Google Show fit	proline rich 18
chr24_-_4418454 Show fit	4.38	ENSDART00000066835	fzd8a NCBI UniProt ZFIN ENSEMBL Google Show fit	frizzled class receptor 8a
chr20_-_53560663 Show fit	4.36	ENSDART00000146001	wasf1 NCBI UniProt ZFIN ENSEMBL Google Show fit	WAS protein family, member 1
chr10_+_404464 Show fit	4.36	ENSDART00000145124 ENSDART00000124319	dact3a NCBI UniProt ZFIN ENSEMBL Google Show fit	dishevelled-binding antagonist of beta-catenin 3a
KN150495v1_-_20497 Show fit	4.35
chr21_-_43806271 Show fit	4.34	ENSDART00000138710	pdlim4 NCBI UniProt ZFIN ENSEMBL Google Show fit	PDZ and LIM domain 4
chr14_-_2682064 Show fit	4.34	ENSDART00000161677	si:dkey-201i24.6 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-201i24.6
chr23_-_28420470 Show fit	4.33	ENSDART00000145072	neurod4 NCBI UniProt ZFIN ENSEMBL Google Show fit	neuronal differentiation 4
chr15_-_20532537 Show fit	4.32	ENSDART00000018514	dlc NCBI UniProt ZFIN ENSEMBL Google Show fit	deltaC
chr8_+_6989445 Show fit	4.31	ENSDART00000134440	gpd1a NCBI UniProt ZFIN ENSEMBL Google Show fit	glycerol-3-phosphate dehydrogenase 1a
chr14_+_21531709 Show fit	4.30	ENSDART00000144367	ctbp1 NCBI UniProt ZFIN ENSEMBL Google Show fit	C-terminal binding protein 1
chr5_-_65349550 Show fit	4.26	ENSDART00000164228	nrarpb NCBI UniProt ZFIN ENSEMBL Google Show fit	notch-regulated ankyrin repeat protein b
chr11_-_28367271 Show fit	4.24	ENSDART00000065853	dhrs3b NCBI UniProt ZFIN ENSEMBL Google Show fit	dehydrogenase/reductase (SDR family) member 3b
chr10_+_9716807 Show fit	4.24	ENSDART00000064977	si:ch211-243g18.2 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch211-243g18.2
chr18_+_26437604 Show fit	4.24	ENSDART00000060245	ctsh NCBI UniProt ZFIN ENSEMBL Google Show fit	cathepsin H
chr8_-_24991984 Show fit	4.23	ENSDART00000078795	ahcyl1 NCBI UniProt ZFIN ENSEMBL Google Show fit	adenosylhomocysteinase-like 1
chr1_+_54231447 Show fit	4.23	ENSDART00000145652	golga7ba NCBI UniProt ZFIN ENSEMBL Google Show fit	golgin A7 family, member Ba
chr5_+_53854279 Show fit	4.22	ENSDART00000165889	tprn NCBI UniProt ZFIN ENSEMBL Google Show fit	taperin
chr3_+_12401750 Show fit	4.20	ENSDART00000167177	ccnf NCBI UniProt ZFIN ENSEMBL Google Show fit	cyclin F
chr7_+_44373815 Show fit	4.19	ENSDART00000170721	si:dkey-56m19.5 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:dkey-56m19.5
chr6_+_2849460 Show fit	4.18
chr20_+_37940880 Show fit	4.16	ENSDART00000165887	flvcr1 NCBI UniProt ZFIN ENSEMBL Google Show fit	feline leukemia virus subgroup C cellular receptor 1
chr4_+_3344998 Show fit	4.15	ENSDART00000075320	nampta NCBI UniProt ZFIN ENSEMBL Google Show fit	nicotinamide phosphoribosyltransferase a
chr23_+_24141576 Show fit	4.15

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.4	13.1	GO:0070587	regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
4.1	12.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
2.9	8.8	GO:0006600	creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
2.3	6.8	GO:0072025	distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
2.1	4.3	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
2.0	6.1	GO:0042023	regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
1.8	12.3	GO:0021628	olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
1.7	7.0	GO:0035633	maintenance of blood-brain barrier(GO:0035633)
1.7	8.6	GO:0046677	response to antibiotic(GO:0046677)
1.7	5.2	GO:0099550	trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
1.7	5.1	GO:0072578	neurotransmitter-gated ion channel clustering(GO:0072578)
1.7	5.1	GO:0017185	peptidyl-lysine hydroxylation(GO:0017185)
1.7	6.7	GO:0099565	chemical synaptic transmission, postsynaptic(GO:0099565)
1.7	9.9	GO:0061298	retina vasculature development in camera-type eye(GO:0061298)
1.6	8.1	GO:0045582	positive regulation of T cell differentiation(GO:0045582)
1.6	4.7	GO:1990535	neuron projection maintenance(GO:1990535)
1.5	6.1	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
1.5	4.5	GO:0098881	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
1.5	10.4	GO:0060088	auditory receptor cell morphogenesis(GO:0002093) auditory receptor cell stereocilium organization(GO:0060088)
1.5	7.4	GO:0051899	membrane depolarization(GO:0051899)
1.5	4.4	GO:0060898	eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
1.4	8.5	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
1.4	4.2	GO:0097037	heme export(GO:0097037)
1.4	4.1	GO:0009957	epidermal cell fate specification(GO:0009957) cranial ganglion development(GO:0061550)
1.3	5.4	GO:0016199	axon midline choice point recognition(GO:0016199)
1.3	10.8	GO:0071557	histone H3-K27 demethylation(GO:0071557)
1.3	3.9	GO:0033690	positive regulation of osteoblast proliferation(GO:0033690)
1.3	3.9	GO:1904398	regulation of synaptic growth at neuromuscular junction(GO:0008582) axon regeneration at neuromuscular junction(GO:0014814) positive regulation of synaptic growth at neuromuscular junction(GO:0045887) positive regulation of neuromuscular junction development(GO:1904398)
1.3	5.2	GO:0010801	regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
1.3	7.6	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
1.3	6.3	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
1.2	3.7	GO:0014821	phasic smooth muscle contraction(GO:0014821)
1.2	3.7	GO:0061031	endodermal digestive tract morphogenesis(GO:0061031)
1.2	11.0	GO:0001709	cell fate determination(GO:0001709)
1.2	2.4	GO:0018197	peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
1.2	8.3	GO:0019226	transmission of nerve impulse(GO:0019226)
1.1	3.4	GO:1903045	neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
1.1	7.9	GO:0021885	forebrain cell migration(GO:0021885)
1.1	28.8	GO:0048010	vascular endothelial growth factor receptor signaling pathway(GO:0048010)
1.1	3.3	GO:0097435	fibril organization(GO:0097435)
1.1	4.3	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
1.1	3.2	GO:0061614	pri-miRNA transcription from RNA polymerase II promoter(GO:0061614) regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902893) positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
1.1	7.4	GO:0006868	glutamine transport(GO:0006868)
1.1	3.2	GO:0031062	positive regulation of histone methylation(GO:0031062)
1.0	5.2	GO:0048795	swim bladder morphogenesis(GO:0048795)
1.0	17.1	GO:0032526	response to retinoic acid(GO:0032526)
1.0	4.0	GO:0035777	pronephric distal tubule development(GO:0035777)
1.0	6.9	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
1.0	2.9	GO:0002706	regulation of lymphocyte mediated immunity(GO:0002706)
1.0	7.6	GO:0045667	regulation of osteoblast differentiation(GO:0045667)
0.9	7.1	GO:0021535	cell migration in hindbrain(GO:0021535)
0.9	4.3	GO:0001839	neural plate morphogenesis(GO:0001839)
0.9	4.3	GO:0006116	NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.9	9.5	GO:0032986	nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.9	2.6	GO:0032656	interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
0.8	4.2	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.8	2.5	GO:0070983	dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.8	4.8	GO:0007343	egg activation(GO:0007343)
0.8	9.4	GO:0097475	motor neuron migration(GO:0097475)
0.8	3.9	GO:0002455	humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.8	9.2	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.7	3.7	GO:0048635	negative regulation of muscle organ development(GO:0048635)
0.7	15.1	GO:0030878	thyroid gland development(GO:0030878)
0.7	5.0	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.7	2.8	GO:0000050	urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.7	5.0	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.7	2.1	GO:0072045	paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341) convergent extension involved in nephron morphogenesis(GO:0072045)
0.7	2.1	GO:0010586	miRNA metabolic process(GO:0010586)
0.7	5.5	GO:0033278	cell proliferation in midbrain(GO:0033278)
0.7	2.7	GO:0051823	regulation of synapse structural plasticity(GO:0051823)
0.7	2.0	GO:0006478	protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.7	2.0	GO:0050748	N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
0.7	2.0	GO:0003228	atrial cardiac muscle tissue development(GO:0003228)
0.7	6.5	GO:0042572	retinol metabolic process(GO:0042572)
0.6	3.9	GO:0043620	regulation of transcription from RNA polymerase II promoter in response to stress(GO:0043618) regulation of DNA-templated transcription in response to stress(GO:0043620)
0.6	7.1	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.6	3.2	GO:0071379	cellular response to prostaglandin stimulus(GO:0071379)
0.6	22.9	GO:0050772	positive regulation of axonogenesis(GO:0050772)
0.6	8.1	GO:0030574	collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.6	1.8	GO:0038161	prolactin signaling pathway(GO:0038161)
0.6	4.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.6	1.8	GO:0019835	cytolysis(GO:0019835)
0.6	3.5	GO:0045670	regulation of osteoclast differentiation(GO:0045670)
0.6	2.3	GO:0006751	glutathione catabolic process(GO:0006751) response to estradiol(GO:0032355)
0.6	2.9	GO:0061162	establishment of apical/basal cell polarity(GO:0035089) establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.6	3.5	GO:0010960	magnesium ion homeostasis(GO:0010960)
0.6	1.1	GO:1901379	regulation of potassium ion transport(GO:0043266) regulation of potassium ion transmembrane transport(GO:1901379)
0.5	21.9	GO:0007050	cell cycle arrest(GO:0007050)
0.5	6.0	GO:0060974	cell migration involved in heart formation(GO:0060974)
0.5	7.4	GO:0061154	endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.5	4.7	GO:0097341	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.5	4.6	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.5	3.1	GO:0015721	bile acid and bile salt transport(GO:0015721)
0.5	9.1	GO:0071711	basement membrane organization(GO:0071711)
0.5	4.5	GO:0032264	IMP salvage(GO:0032264)
0.5	6.0	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.5	6.9	GO:0015804	neutral amino acid transport(GO:0015804)
0.5	7.4	GO:1903672	positive regulation of sprouting angiogenesis(GO:1903672)
0.5	3.9	GO:0033555	multicellular organismal response to stress(GO:0033555)
0.5	2.8	GO:0033138	positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.5	2.3	GO:0072512	ferric iron transport(GO:0015682) transferrin transport(GO:0033572) trivalent inorganic cation transport(GO:0072512)
0.5	0.5	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.5	6.8	GO:0040023	nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.5	1.4	GO:0031639	plasminogen activation(GO:0031639)
0.5	5.9	GO:0060561	apoptotic process involved in morphogenesis(GO:0060561)
0.4	2.2	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.4	10.2	GO:0007632	visual behavior(GO:0007632)
0.4	1.7	GO:0021703	locus ceruleus development(GO:0021703)
0.4	2.2	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.4	5.2	GO:0033173	calcineurin-NFAT signaling cascade(GO:0033173)
0.4	6.4	GO:0051149	positive regulation of myoblast differentiation(GO:0045663) positive regulation of muscle cell differentiation(GO:0051149)
0.4	7.1	GO:0036376	cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.4	2.9	GO:0006584	catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.4	0.8	GO:0002762	negative regulation of myeloid leukocyte differentiation(GO:0002762) regulation of granulocyte differentiation(GO:0030852) regulation of neutrophil differentiation(GO:0045658)
0.4	4.3	GO:0010770	positive regulation of cell morphogenesis involved in differentiation(GO:0010770)
0.4	7.4	GO:0061462	protein localization to lysosome(GO:0061462)
0.4	9.3	GO:0042149	cellular response to glucose starvation(GO:0042149)
0.4	1.5	GO:0035332	positive regulation of hippo signaling(GO:0035332)
0.4	2.3	GO:0010332	response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.4	4.6	GO:0044247	polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.4	3.0	GO:0048796	swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.4	4.9	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.4	4.5	GO:0001678	cellular glucose homeostasis(GO:0001678)
0.4	6.3	GO:0030199	collagen fibril organization(GO:0030199)
0.4	2.6	GO:0070650	actin filament bundle distribution(GO:0070650)
0.4	0.7	GO:0099601	regulation of neurotransmitter receptor activity(GO:0099601)
0.3	6.6	GO:0050654	chondroitin sulfate proteoglycan metabolic process(GO:0050654)
0.3	7.2	GO:0060219	camera-type eye photoreceptor cell differentiation(GO:0060219)
0.3	1.7	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.3	2.0	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.3	6.7	GO:0031952	regulation of protein autophosphorylation(GO:0031952)
0.3	2.3	GO:0044458	motile cilium assembly(GO:0044458)
0.3	1.3	GO:0035881	amacrine cell differentiation(GO:0035881)
0.3	2.0	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.3	8.7	GO:0060119	inner ear receptor cell development(GO:0060119)
0.3	2.0	GO:0045110	intermediate filament bundle assembly(GO:0045110)
0.3	3.6	GO:0060021	palate development(GO:0060021)
0.3	1.0	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.3	4.6	GO:0045454	cell redox homeostasis(GO:0045454)
0.3	3.9	GO:0061099	negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.3	3.2	GO:0061300	cerebellum vasculature development(GO:0061300)
0.3	1.6	GO:0043535	regulation of blood vessel endothelial cell migration(GO:0043535)
0.3	5.9	GO:0008354	germ cell migration(GO:0008354)
0.3	2.8	GO:1902254	regulation of retinal ganglion cell axon guidance(GO:0090259) negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.3	4.6	GO:0031581	hemidesmosome assembly(GO:0031581)
0.3	16.2	GO:0035567	non-canonical Wnt signaling pathway(GO:0035567)
0.3	1.5	GO:0030316	osteoclast differentiation(GO:0030316)
0.3	3.5	GO:0046620	regulation of organ growth(GO:0046620)
0.3	3.5	GO:0070286	axonemal dynein complex assembly(GO:0070286)
0.3	4.6	GO:0060319	primitive erythrocyte differentiation(GO:0060319)
0.3	6.0	GO:0048268	clathrin coat assembly(GO:0048268)
0.3	3.8	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.3	1.3	GO:0051177	meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.3	3.2	GO:2000601	positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.3	0.8	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.3	2.7	GO:0061337	cardiac conduction(GO:0061337)
0.3	1.3	GO:0006741	NADP biosynthetic process(GO:0006741)
0.3	2.9	GO:0090311	regulation of histone deacetylation(GO:0031063) regulation of protein deacetylation(GO:0090311)
0.2	1.7	GO:0072160	pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014) nephron tubule epithelial cell differentiation(GO:0072160)
0.2	4.2	GO:0048382	mesendoderm development(GO:0048382)
0.2	2.2	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.2	1.7	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.2	20.9	GO:0043062	extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.2	1.5	GO:0061075	positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.2	4.8	GO:0030032	lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.2	9.4	GO:0030835	regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) actin filament capping(GO:0051693)
0.2	0.2	GO:0033144	negative regulation of intracellular steroid hormone receptor signaling pathway(GO:0033144)
0.2	4.9	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.2	1.4	GO:0035094	response to nicotine(GO:0035094)
0.2	0.2	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059) negative regulation of ERBB signaling pathway(GO:1901185)
0.2	2.5	GO:0046686	response to cadmium ion(GO:0046686)
0.2	5.5	GO:0048263	determination of dorsal identity(GO:0048263)
0.2	3.5	GO:0061035	regulation of cartilage development(GO:0061035)
0.2	5.4	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.2	1.9	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.2	1.3	GO:0030216	keratinocyte differentiation(GO:0030216)
0.2	0.4	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.2	1.5	GO:1902914	negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.2	0.9	GO:0007413	axonal fasciculation(GO:0007413)
0.2	5.6	GO:0045666	positive regulation of neuron differentiation(GO:0045666)
0.2	5.5	GO:0060037	pharyngeal system development(GO:0060037)
0.2	4.5	GO:1902653	cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.2	2.0	GO:0030168	platelet activation(GO:0030168)
0.2	0.6	GO:0002934	desmosome organization(GO:0002934)
0.2	3.4	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.2	4.2	GO:0002028	regulation of sodium ion transport(GO:0002028)
0.2	2.0	GO:0051382	kinetochore assembly(GO:0051382)
0.2	0.6	GO:0019242	methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2	1.5	GO:0006013	mannose metabolic process(GO:0006013)
0.2	0.8	GO:0048339	paraxial mesoderm development(GO:0048339)
0.2	9.9	GO:0006414	translational elongation(GO:0006414)
0.2	0.6	GO:0060832	oocyte animal/vegetal axis specification(GO:0060832)
0.2	0.6	GO:0035776	pronephric proximal tubule development(GO:0035776)
0.2	1.9	GO:0000186	activation of MAPKK activity(GO:0000186)
0.2	1.5	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.2	3.5	GO:0043049	otic placode formation(GO:0043049)
0.2	2.4	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.2	1.8	GO:0007398	ectoderm development(GO:0007398)
0.2	3.6	GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.2	3.6	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.2	3.4	GO:0030513	positive regulation of BMP signaling pathway(GO:0030513)
0.2	3.5	GO:0014866	skeletal myofibril assembly(GO:0014866)
0.2	0.7	GO:0006864	pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.2	1.4	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.2	1.0	GO:2001106	regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.2	2.3	GO:0030309	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2	10.2	GO:0001708	cell fate specification(GO:0001708)
0.2	1.0	GO:0045580	regulation of T cell differentiation(GO:0045580)
0.2	2.7	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.2	1.8	GO:0097178	ruffle organization(GO:0031529) ruffle assembly(GO:0097178)
0.2	0.5	GO:0046655	folic acid metabolic process(GO:0046655)
0.1	0.6	GO:0022900	electron transport chain(GO:0022900)
0.1	1.5	GO:0032291	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1	0.6	GO:0010996	response to auditory stimulus(GO:0010996)
0.1	0.9	GO:0008210	estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.1	5.4	GO:0006469	negative regulation of protein kinase activity(GO:0006469)
0.1	0.4	GO:0098773	skin epidermis development(GO:0098773)
0.1	13.9	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1	0.1	GO:1904357	negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.1	1.6	GO:0018279	peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.1	0.7	GO:0010990	SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.1	4.2	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1	0.4	GO:0070640	vitamin D3 metabolic process(GO:0070640)
0.1	1.9	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	0.9	GO:1900449	regulation of glutamate receptor signaling pathway(GO:1900449)
0.1	0.9	GO:0018298	protein-chromophore linkage(GO:0018298)
0.1	1.0	GO:0035305	negative regulation of dephosphorylation(GO:0035305) negative regulation of protein dephosphorylation(GO:0035308)
0.1	3.8	GO:1903844	regulation of transforming growth factor beta receptor signaling pathway(GO:0017015) regulation of cellular response to transforming growth factor beta stimulus(GO:1903844)
0.1	0.5	GO:0008592	regulation of Toll signaling pathway(GO:0008592)
0.1	1.4	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	0.9	GO:0045050	protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050)
0.1	1.4	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.1	0.7	GO:0072576	liver morphogenesis(GO:0072576)
0.1	0.7	GO:0007622	rhythmic behavior(GO:0007622) circadian behavior(GO:0048512)
0.1	6.2	GO:0030155	regulation of cell adhesion(GO:0030155)
0.1	0.4	GO:0032978	protein insertion into membrane from inner side(GO:0032978) protein insertion into mitochondrial membrane from inner side(GO:0032979) protein insertion into mitochondrial membrane(GO:0051204)
0.1	2.0	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.1	0.6	GO:1902624	positive regulation of neutrophil migration(GO:1902624)
0.1	1.9	GO:0050768	negative regulation of neurogenesis(GO:0050768)
0.1	4.1	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
0.1	1.4	GO:0036465	synaptic vesicle recycling(GO:0036465) synaptic vesicle endocytosis(GO:0048488)
0.1	0.8	GO:0046470	phosphatidylcholine metabolic process(GO:0046470)
0.1	6.2	GO:0048565	digestive tract development(GO:0048565)
0.1	0.9	GO:0030259	lipid glycosylation(GO:0030259)
0.1	1.1	GO:0046627	negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1	1.3	GO:0006094	gluconeogenesis(GO:0006094)
0.1	6.4	GO:0050770	regulation of axonogenesis(GO:0050770)
0.1	0.9	GO:0035493	SNARE complex assembly(GO:0035493)
0.1	1.0	GO:0006189	'de novo' IMP biosynthetic process(GO:0006189)
0.1	3.5	GO:0010466	negative regulation of peptidase activity(GO:0010466)
0.1	2.0	GO:0060326	cell chemotaxis(GO:0060326)
0.1	0.4	GO:0051904	melanosome transport(GO:0032402) pigment granule transport(GO:0051904)
0.1	2.4	GO:0070509	calcium ion import(GO:0070509)
0.1	1.5	GO:0046928	regulation of neurotransmitter secretion(GO:0046928)
0.1	1.3	GO:0043627	response to estrogen(GO:0043627)
0.1	1.7	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.1	3.6	GO:0030239	myofibril assembly(GO:0030239)
0.1	1.0	GO:0045766	positive regulation of angiogenesis(GO:0045766)
0.1	2.6	GO:1902600	hydrogen ion transmembrane transport(GO:1902600)
0.1	0.7	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.1	0.3	GO:0036371	protein localization to T-tubule(GO:0036371)
0.1	2.5	GO:0031032	actomyosin structure organization(GO:0031032)
0.1	0.2	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.1	0.2	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.1	2.1	GO:0048278	vesicle docking(GO:0048278)
0.1	1.1	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.1	6.0	GO:0007411	axon guidance(GO:0007411)
0.1	0.8	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1	2.9	GO:0061640	cytoskeleton-dependent cytokinesis(GO:0061640)
0.1	2.2	GO:0070121	Kupffer's vesicle development(GO:0070121)
0.1	6.1	GO:0060548	negative regulation of cell death(GO:0060548)
0.1	0.6	GO:0006911	phagocytosis, engulfment(GO:0006911)
0.1	5.7	GO:0007268	chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916)
0.1	1.1	GO:0007041	lysosomal transport(GO:0007041)
0.1	0.9	GO:0007528	neuromuscular junction development(GO:0007528)
0.0	0.5	GO:0032438	melanosome organization(GO:0032438)
0.0	0.3	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.0	0.8	GO:0007416	synapse assembly(GO:0007416)
0.0	0.7	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	4.2	GO:0006352	DNA-templated transcription, initiation(GO:0006352)
0.0	3.6	GO:0045333	cellular respiration(GO:0045333)
0.0	0.8	GO:0007548	sex differentiation(GO:0007548)
0.0	2.9	GO:0016485	protein processing(GO:0016485)
0.0	0.3	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961)
0.0	0.5	GO:0009950	dorsal/ventral axis specification(GO:0009950)
0.0	0.8	GO:0006909	phagocytosis(GO:0006909)
0.0	0.9	GO:0030705	cytoskeleton-dependent intracellular transport(GO:0030705)
0.0	0.6	GO:0006383	transcription from RNA polymerase III promoter(GO:0006383)
0.0	0.5	GO:0000737	DNA catabolic process, endonucleolytic(GO:0000737)
0.0	0.3	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.8	GO:0006301	postreplication repair(GO:0006301)
0.0	0.6	GO:0051568	histone H3-K4 methylation(GO:0051568)
0.0	1.2	GO:0090090	negative regulation of canonical Wnt signaling pathway(GO:0090090)
0.0	0.4	GO:0006896	Golgi to vacuole transport(GO:0006896)
0.0	0.2	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0	3.3	GO:0007018	microtubule-based movement(GO:0007018)
0.0	1.1	GO:0031018	endocrine pancreas development(GO:0031018)
0.0	1.9	GO:0048024	regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0	0.3	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.3	GO:0043486	histone exchange(GO:0043486)
0.0	0.1	GO:0098969	neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.0	0.4	GO:0090263	positive regulation of canonical Wnt signaling pathway(GO:0090263)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	20.7	GO:0031680	G-protein beta/gamma-subunit complex(GO:0031680)
1.8	9.2	GO:0008091	spectrin(GO:0008091)
1.7	6.7	GO:0070062	extracellular exosome(GO:0070062)
1.6	6.5	GO:0098644	complex of collagen trimers(GO:0098644)
1.2	6.0	GO:0098890	extrinsic component of postsynaptic membrane(GO:0098890)
1.2	14.3	GO:0043209	myelin sheath(GO:0043209)
1.2	9.2	GO:0090533	sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
1.0	10.0	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.9	8.9	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.9	2.6	GO:1990590	ATF1-ATF4 transcription factor complex(GO:1990590)
0.8	5.0	GO:0048179	activin receptor complex(GO:0048179)
0.8	3.9	GO:0005579	membrane attack complex(GO:0005579)
0.7	4.3	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.7	3.5	GO:0048788	cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.7	11.1	GO:0071564	npBAF complex(GO:0071564)
0.7	4.1	GO:1990246	uniplex complex(GO:1990246)
0.7	7.9	GO:0031209	SCAR complex(GO:0031209)
0.7	2.0	GO:0030314	junctional membrane complex(GO:0030314)
0.6	7.7	GO:0014704	intercalated disc(GO:0014704)
0.6	7.6	GO:0005640	nuclear outer membrane(GO:0005640)
0.5	6.8	GO:0005869	dynactin complex(GO:0005869)
0.5	7.2	GO:0044666	MLL3/4 complex(GO:0044666)
0.5	14.3	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.5	38.1	GO:0005882	intermediate filament(GO:0005882)
0.4	4.5	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.4	5.1	GO:0098839	postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.4	4.2	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.4	19.7	GO:0042641	actomyosin(GO:0042641)
0.3	17.6	GO:0005581	collagen trimer(GO:0005581)
0.3	2.9	GO:0009925	basal plasma membrane(GO:0009925)
0.3	2.3	GO:0002116	semaphorin receptor complex(GO:0002116)
0.3	7.4	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.3	1.6	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.3	4.6	GO:0043195	terminal bouton(GO:0043195)
0.3	7.0	GO:0032156	septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.3	1.8	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.3	5.0	GO:0030057	desmosome(GO:0030057)
0.3	15.6	GO:0005871	kinesin complex(GO:0005871)
0.3	10.7	GO:0005604	basement membrane(GO:0005604) extracellular matrix component(GO:0044420)
0.3	1.0	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.3	8.1	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.2	9.9	GO:0005905	clathrin-coated pit(GO:0005905)
0.2	8.2	GO:0005901	caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.2	1.1	GO:0032420	stereocilium(GO:0032420)
0.2	1.5	GO:0042734	presynaptic membrane(GO:0042734)
0.2	8.4	GO:0043197	dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.2	3.3	GO:0048786	presynaptic active zone(GO:0048786)
0.2	1.2	GO:0034704	calcium channel complex(GO:0034704)
0.2	2.9	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.2	9.8	GO:0031012	extracellular matrix(GO:0031012)
0.2	1.1	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.2	6.5	GO:0099572	postsynaptic specialization(GO:0099572)
0.2	1.2	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.2	32.5	GO:0043235	receptor complex(GO:0043235)
0.2	5.0	GO:0031225	anchored component of membrane(GO:0031225)
0.2	21.1	GO:0030424	axon(GO:0030424)
0.2	3.9	GO:0060293	germ plasm(GO:0060293)
0.2	1.7	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.1	6.7	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	4.6	GO:0005811	lipid particle(GO:0005811)
0.1	0.8	GO:0005921	gap junction(GO:0005921)
0.1	4.9	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	0.6	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.1	1.0	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	1.1	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1	1.6	GO:0000145	exocyst(GO:0000145)
0.1	2.2	GO:0032587	ruffle membrane(GO:0032587)
0.1	51.6	GO:0005887	integral component of plasma membrane(GO:0005887)
0.1	2.3	GO:0030426	growth cone(GO:0030426)
0.1	3.0	GO:0042383	sarcolemma(GO:0042383)
0.1	3.9	GO:0016605	PML body(GO:0016605)
0.1	0.2	GO:0060076	excitatory synapse(GO:0060076)
0.1	1.2	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.1	3.1	GO:0030863	cortical cytoskeleton(GO:0030863)
0.1	49.2	GO:0005615	extracellular space(GO:0005615)
0.1	4.6	GO:0005776	autophagosome(GO:0005776)
0.1	1.6	GO:0005801	cis-Golgi network(GO:0005801)
0.1	9.4	GO:0005912	adherens junction(GO:0005912) anchoring junction(GO:0070161)
0.1	1.1	GO:0016272	prefoldin complex(GO:0016272)
0.1	0.5	GO:0000839	Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1	3.3	GO:0022626	cytosolic ribosome(GO:0022626) cytosolic small ribosomal subunit(GO:0022627)
0.1	5.6	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.1	1.4	GO:0043025	neuronal cell body(GO:0043025)
0.1	4.7	GO:0070382	exocytic vesicle(GO:0070382)
0.1	2.9	GO:0016459	myosin complex(GO:0016459)
0.1	2.7	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1	0.9	GO:0072546	ER membrane protein complex(GO:0072546)
0.1	2.7	GO:0005884	actin filament(GO:0005884)
0.1	3.5	GO:0036064	ciliary basal body(GO:0036064)
0.1	5.5	GO:0000786	nucleosome(GO:0000786)
0.1	2.2	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	2.5	GO:0072686	mitotic spindle(GO:0072686)
0.0	3.7	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.0	0.1	GO:1990879	CST complex(GO:1990879)
0.0	0.8	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.8	GO:0042555	MCM complex(GO:0042555)
0.0	0.2	GO:0031501	mannosyltransferase complex(GO:0031501)
0.0	1.3	GO:0005865	striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.0	0.4	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.7	GO:0016282	eukaryotic 43S preinitiation complex(GO:0016282)
0.0	0.6	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	86.0	GO:0016021	integral component of membrane(GO:0016021)
0.0	0.3	GO:0000812	Swr1 complex(GO:0000812)
0.0	4.0	GO:0005681	spliceosomal complex(GO:0005681)
0.0	0.8	GO:0030018	Z disc(GO:0030018)
0.0	1.3	GO:0016592	mediator complex(GO:0016592)
0.0	0.6	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	2.4	GO:0005874	microtubule(GO:0005874)
0.0	0.6	GO:0009986	cell surface(GO:0009986)
0.0	0.7	GO:0035097	histone methyltransferase complex(GO:0035097)
0.0	0.5	GO:0030027	lamellipodium(GO:0030027)
0.0	0.3	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.7	8.0	GO:0070548	glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360) L-glutamine aminotransferase activity(GO:0070548)
2.6	7.8	GO:0098639	C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
2.6	7.7	GO:0005463	UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
1.7	20.7	GO:0031681	G-protein beta-subunit binding(GO:0031681)
1.6	4.8	GO:0070644	vitamin D response element binding(GO:0070644)
1.5	12.2	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
1.4	24.7	GO:0005112	Notch binding(GO:0005112)
1.3	10.8	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
1.3	6.7	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.3	7.9	GO:0016801	hydrolase activity, acting on ether bonds(GO:0016801)
1.3	18.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
1.2	5.0	GO:0016361	activin receptor activity, type I(GO:0016361)
1.1	12.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
1.1	2.2	GO:0050431	transforming growth factor beta binding(GO:0050431)
1.1	6.5	GO:0004745	retinol dehydrogenase activity(GO:0004745)
1.1	20.6	GO:0042813	Wnt-activated receptor activity(GO:0042813)
1.1	4.3	GO:0030274	LIM domain binding(GO:0030274)
1.1	3.2	GO:0004953	icosanoid receptor activity(GO:0004953)
1.0	4.1	GO:0004736	pyruvate carboxylase activity(GO:0004736)
1.0	3.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
1.0	5.0	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
1.0	2.9	GO:0047751	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) enone reductase activity(GO:0035671) cholestenone 5-alpha-reductase activity(GO:0047751)
1.0	5.9	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) glucose binding(GO:0005536) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
1.0	2.9	GO:0008131	primary amine oxidase activity(GO:0008131)
1.0	4.8	GO:0072349	modified amino acid transmembrane transporter activity(GO:0072349)
1.0	6.7	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.9	2.8	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.9	12.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.9	3.7	GO:0005119	smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.9	4.6	GO:0004645	phosphorylase activity(GO:0004645) glycogen phosphorylase activity(GO:0008184)
0.9	7.9	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.9	4.3	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.9	0.9	GO:0005003	ephrin receptor activity(GO:0005003)
0.8	7.4	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.8	4.9	GO:0019956	chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.8	2.4	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.8	10.9	GO:0005080	protein kinase C binding(GO:0005080)
0.8	2.3	GO:0000048	peptidyltransferase activity(GO:0000048) glutathione hydrolase activity(GO:0036374)
0.8	3.9	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.8	3.1	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.7	6.5	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.7	5.6	GO:0004859	phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.7	5.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.7	2.7	GO:0034481	chondroitin sulfotransferase activity(GO:0034481)
0.7	4.0	GO:0048039	ubiquinone binding(GO:0048039)
0.7	6.7	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.7	2.0	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.7	6.6	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.7	2.0	GO:0008476	protein-tyrosine sulfotransferase activity(GO:0008476)
0.7	2.0	GO:0043515	kinetochore binding(GO:0043515)
0.7	5.9	GO:0005504	fatty acid binding(GO:0005504)
0.6	2.6	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.6	4.5	GO:0048185	activin binding(GO:0048185)
0.6	6.3	GO:0016405	CoA-ligase activity(GO:0016405)
0.6	2.5	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.6	1.8	GO:0004925	prolactin receptor activity(GO:0004925)
0.6	12.6	GO:0051393	muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.6	5.3	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.6	2.2	GO:0098882	structural constituent of presynaptic active zone(GO:0098882)
0.5	8.0	GO:0001540	beta-amyloid binding(GO:0001540)
0.5	1.6	GO:0004576	oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.5	4.7	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.5	9.3	GO:0016769	transferase activity, transferring nitrogenous groups(GO:0016769)
0.5	5.7	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.5	2.6	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.5	30.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.5	6.9	GO:0015175	neutral amino acid transmembrane transporter activity(GO:0015175)
0.5	1.9	GO:1990518	ATP-dependent 3'-5' DNA helicase activity(GO:0043140) single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity(GO:1990518)
0.5	2.3	GO:0004998	transferrin receptor activity(GO:0004998)
0.5	14.4	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.5	1.4	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.4	1.7	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.4	6.0	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.4	3.0	GO:0031682	G-protein gamma-subunit binding(GO:0031682)
0.4	4.6	GO:0030506	ankyrin binding(GO:0030506)
0.4	7.1	GO:0001671	ATPase activator activity(GO:0001671)
0.4	1.6	GO:0050211	procollagen galactosyltransferase activity(GO:0050211)
0.4	2.0	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.4	4.2	GO:0015232	heme transporter activity(GO:0015232)
0.4	2.6	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.4	3.6	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.4	6.8	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.4	5.3	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.3	6.4	GO:0046875	ephrin receptor binding(GO:0046875)
0.3	3.4	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.3	4.7	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.3	12.7	GO:0042826	histone deacetylase binding(GO:0042826)
0.3	1.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.3	18.4	GO:0045296	cadherin binding(GO:0045296)
0.3	1.3	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3	1.6	GO:0008312	7S RNA binding(GO:0008312)
0.3	23.6	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.3	1.9	GO:0001223	transcription coactivator binding(GO:0001223)
0.3	0.9	GO:0016918	retinal binding(GO:0016918)
0.3	2.5	GO:0050699	WW domain binding(GO:0050699)
0.3	0.9	GO:0033842	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.3	22.9	GO:0042802	identical protein binding(GO:0042802)
0.3	1.2	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.3	2.0	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.3	1.5	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3	5.8	GO:0031418	L-ascorbic acid binding(GO:0031418)
0.3	10.9	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.3	1.1	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.3	2.0	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.3	1.1	GO:0004362	glutathione-disulfide reductase activity(GO:0004362)
0.3	10.6	GO:0019209	kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.3	7.8	GO:0017147	Wnt-protein binding(GO:0017147)
0.3	0.8	GO:0005243	gap junction channel activity(GO:0005243)
0.3	5.1	GO:0019211	phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.3	3.7	GO:1990782	receptor tyrosine kinase binding(GO:0030971) protein tyrosine kinase binding(GO:1990782)
0.3	3.5	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.3	2.8	GO:0008266	poly(U) RNA binding(GO:0008266)
0.3	5.6	GO:0017075	syntaxin-1 binding(GO:0017075)
0.3	2.3	GO:0017154	semaphorin receptor activity(GO:0017154)
0.3	1.3	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.2	1.0	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.2	11.1	GO:0005179	hormone activity(GO:0005179)
0.2	1.5	GO:0060182	apelin receptor activity(GO:0060182)
0.2	2.9	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.2	9.8	GO:0003777	microtubule motor activity(GO:0003777)
0.2	6.0	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.2	3.9	GO:0019210	protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.2	2.0	GO:0042043	neurexin family protein binding(GO:0042043)
0.2	2.9	GO:0042562	hormone binding(GO:0042562)
0.2	2.4	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2	2.6	GO:0003785	actin monomer binding(GO:0003785)
0.2	1.0	GO:0004639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.2	12.4	GO:0030414	peptidase inhibitor activity(GO:0030414)
0.2	1.6	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.2	90.1	GO:0046983	protein dimerization activity(GO:0046983)
0.2	1.2	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.2	3.1	GO:0030165	PDZ domain binding(GO:0030165)
0.2	1.0	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.2	2.0	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.2	2.1	GO:0005158	insulin receptor binding(GO:0005158)
0.2	4.5	GO:0032451	demethylase activity(GO:0032451)
0.2	7.6	GO:0003727	single-stranded RNA binding(GO:0003727)
0.2	4.4	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.2	3.3	GO:0005245	voltage-gated calcium channel activity(GO:0005245)
0.2	0.7	GO:0015218	pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.2	3.2	GO:0035497	cAMP response element binding(GO:0035497)
0.2	0.7	GO:0004422	hypoxanthine phosphoribosyltransferase activity(GO:0004422)
0.2	0.7	GO:0070412	R-SMAD binding(GO:0070412)
0.2	2.6	GO:0061608	nuclear import signal receptor activity(GO:0061608)
0.2	2.7	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	6.3	GO:0005484	SNAP receptor activity(GO:0005484)
0.1	10.9	GO:0051082	unfolded protein binding(GO:0051082)
0.1	2.4	GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.1	1.4	GO:0022848	acetylcholine-gated cation channel activity(GO:0022848)
0.1	1.3	GO:0032977	membrane insertase activity(GO:0032977)
0.1	0.7	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1	2.4	GO:0098631	protein binding involved in cell adhesion(GO:0098631)
0.1	10.8	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.7	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.1	0.5	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.1	5.8	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.1	5.6	GO:0004521	endoribonuclease activity(GO:0004521)
0.1	2.1	GO:0035198	miRNA binding(GO:0035198)
0.1	1.2	GO:0016208	AMP binding(GO:0016208)
0.1	0.6	GO:0016723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.1	1.7	GO:0016018	cyclosporin A binding(GO:0016018)
0.1	1.0	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.1	0.5	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.1	3.6	GO:0017124	SH3 domain binding(GO:0017124)
0.1	4.1	GO:0005109	frizzled binding(GO:0005109)
0.1	2.1	GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0033764)
0.1	1.3	GO:0005523	tropomyosin binding(GO:0005523)
0.1	0.3	GO:0003874	6-pyruvoyltetrahydropterin synthase activity(GO:0003874)
0.1	1.2	GO:0030552	cAMP binding(GO:0030552)
0.1	4.1	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	2.6	GO:0008528	G-protein coupled peptide receptor activity(GO:0008528)
0.1	0.3	GO:0015230	FAD transmembrane transporter activity(GO:0015230)
0.1	0.3	GO:0047710	bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.1	1.5	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1	3.6	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1	2.3	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1	0.6	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	0.2	GO:0030331	estrogen receptor binding(GO:0030331)
0.1	0.5	GO:0004530	deoxyribonuclease I activity(GO:0004530)
0.1	0.3	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.1	0.4	GO:0035173	histone kinase activity(GO:0035173)
0.1	5.1	GO:0050660	flavin adenine dinucleotide binding(GO:0050660)
0.1	3.3	GO:0019843	rRNA binding(GO:0019843)
0.1	24.1	GO:0003779	actin binding(GO:0003779)
0.1	3.4	GO:1901981	phosphatidylinositol phosphate binding(GO:1901981)
0.1	7.5	GO:0000287	magnesium ion binding(GO:0000287)
0.1	1.8	GO:0005212	structural constituent of eye lens(GO:0005212)
0.1	1.7	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1	3.0	GO:0051287	NAD binding(GO:0051287)
0.1	0.8	GO:0004622	lysophospholipase activity(GO:0004622)
0.1	7.2	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1	2.2	GO:0015171	amino acid transmembrane transporter activity(GO:0015171)
0.1	9.0	GO:0008017	microtubule binding(GO:0008017)
0.1	1.6	GO:0035064	methylated histone binding(GO:0035064)
0.1	0.8	GO:0038191	neuropilin binding(GO:0038191)
0.1	2.0	GO:0045499	semaphorin receptor binding(GO:0030215) chemorepellent activity(GO:0045499)
0.1	0.9	GO:0004559	alpha-mannosidase activity(GO:0004559)
0.1	0.5	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	9.5	GO:0005085	guanyl-nucleotide exchange factor activity(GO:0005085)
0.0	0.6	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	51.0	GO:0000976	transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.0	0.8	GO:0031386	protein tag(GO:0031386)
0.0	3.2	GO:0042626	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0	2.0	GO:0005125	cytokine activity(GO:0005125)
0.0	1.7	GO:0015631	tubulin binding(GO:0015631)
0.0	0.7	GO:0019955	cytokine binding(GO:0019955)
0.0	0.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.5	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.4	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.5	GO:0001786	phosphatidylserine binding(GO:0001786)
0.0	0.1	GO:0035258	steroid hormone receptor binding(GO:0035258)
0.0	0.6	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	1.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.1	GO:0046964	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0	5.2	GO:0005096	GTPase activator activity(GO:0005096)
0.0	0.2	GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0	0.3	GO:0015379	cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0	9.9	GO:0005525	GTP binding(GO:0005525)
0.0	0.2	GO:0004376	glycolipid mannosyltransferase activity(GO:0004376)
0.0	1.3	GO:0015293	symporter activity(GO:0015293)
0.0	0.2	GO:0015026	coreceptor activity(GO:0015026)
0.0	10.0	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.2	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0	2.0	GO:0003735	structural constituent of ribosome(GO:0003735)
0.0	0.4	GO:0044325	ion channel binding(GO:0044325)
0.0	1.0	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.3	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.1	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.6	20.9	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.9	2.8	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.8	17.7	NABA COLLAGENS	Genes encoding collagen proteins
0.7	8.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.6	1.7	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.5	7.6	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.4	14.7	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.4	0.9	PID IL3 PATHWAY	IL3-mediated signaling events
0.4	6.6	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.4	7.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.4	3.9	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.3	3.5	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3	8.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.3	4.8	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.3	5.4	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.3	7.0	PID NOTCH PATHWAY	Notch signaling pathway
0.3	2.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.3	3.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.3	6.0	PID EPHA FWDPATHWAY	EPHA forward signaling
0.3	9.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.3	9.0	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.3	6.2	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.3	22.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	0.5	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.2	4.6	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.2	4.1	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.2	0.6	PID ERBB4 PATHWAY	ErbB4 signaling events
0.2	2.8	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2	7.4	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.2	5.8	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.2	2.5	PID EPO PATHWAY	EPO signaling pathway
0.2	2.5	PID ALK1 PATHWAY	ALK1 signaling events
0.1	6.9	PID P53 REGULATION PATHWAY	p53 pathway
0.1	6.7	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.1	2.7	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1	1.0	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.1	2.9	PID ILK PATHWAY	Integrin-linked kinase signaling
0.1	1.0	ST GA13 PATHWAY	G alpha 13 Pathway
0.1	1.6	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.1	1.4	PID BCR 5PATHWAY	BCR signaling pathway
0.1	1.2	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	2.6	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.1	0.6	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	1.9	PID ATR PATHWAY	ATR signaling pathway
0.1	0.9	PID ATM PATHWAY	ATM pathway
0.1	2.9	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	1.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	3.4	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.0	0.3	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.2	PID BMP PATHWAY	BMP receptor signaling
0.0	1.2	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.5	PID ARF 3PATHWAY	Arf1 pathway
0.0	1.1	PID E2F PATHWAY	E2F transcription factor network
0.0	0.3	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.1	23.0	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
1.7	7.0	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.3	6.7	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
1.3	9.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
1.2	9.9	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
1.2	11.8	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.9	12.1	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.8	6.5	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.8	2.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.7	6.2	REACTOME BILE ACID AND BILE SALT METABOLISM	Genes involved in Bile acid and bile salt metabolism
0.7	4.6	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.6	14.8	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.6	12.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.6	2.8	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.6	2.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.5	1.5	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.5	1.0	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.5	16.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.5	14.3	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.5	5.5	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.4	3.9	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.4	4.7	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.4	3.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.4	3.5	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.4	7.8	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.4	3.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.4	3.9	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.4	7.5	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.3	3.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3	6.5	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.3	2.9	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.3	5.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.3	1.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.3	3.9	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.3	5.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.3	12.1	REACTOME AMYLOIDS	Genes involved in Amyloids
0.2	2.5	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	4.2	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.2	3.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.2	8.9	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.2	2.9	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.2	1.5	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2	5.9	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.2	1.6	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.2	5.1	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.2	2.1	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.2	2.6	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.2	2.4	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.2	2.6	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	2.0	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	10.0	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	10.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.1	2.0	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	1.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.1	0.9	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.1	1.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	1.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.1	5.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	2.9	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	0.6	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.1	2.5	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	2.5	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	1.7	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	2.5	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.1	1.9	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1	1.0	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	1.5	REACTOME TRANSLATION	Genes involved in Translation
0.1	1.1	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	1.0	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1	0.7	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	0.8	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	3.1	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	2.0	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0	0.3	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.9	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	1.1	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	1.3	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0	1.4	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	0.7	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.6	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.4	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.2	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)

Results for sp1

Z-value: 4.19

Motif logo

Transcription factors associated with sp1

Activity-expression correlation:

Activity profile of sp1 motif

Sorted Z-values of sp1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of sp1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: