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Results for sp3b

Z-value: 1.45

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Transcription factors associated with sp3b

Gene Symbol Gene ID Gene Info
ENSDARG00000007812 Sp3b transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
sp3bdr10_dc_chr6_-_10492123_104921680.639.0e-03Click!

Activity profile of sp3b motif

Sorted Z-values of sp3b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of sp3b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_44892852 4.43 ENSDART00000160961
activating transcription factor 7 interacting protein
chr14_+_268119 4.22

chr7_+_44463158 4.15 ENSDART00000066380
carbonic anhydrase VII
KN149861v1_-_5655 4.09

KN150589v1_-_5839 3.64 ENSDART00000157761
ENSDART00000157531
ELOVL fatty acid elongase 7b
chr23_-_31719203 3.60 ENSDART00000148122
serum/glucocorticoid regulated kinase 1
chr3_+_50398735 3.44

chr8_-_410190 3.40 ENSDART00000151155
tripartite motif containing 36
chr16_+_25344257 3.31 ENSDART00000058938
F-box protein 32
chr5_+_65453249 3.26 ENSDART00000073892
zgc:114041
chr6_+_3174047 3.26 ENSDART00000160290
ST3 beta-galactoside alpha-2,3-sialyltransferase 3a
chr17_-_53241446 3.12

chr25_+_22222388 3.10 ENSDART00000154376
cytochrome P450, family 11, subfamily A, polypeptide 1
chr3_-_18653909 3.08

chr1_-_44893257 2.99 ENSDART00000160961
activating transcription factor 7 interacting protein
chr20_-_194135 2.98 ENSDART00000064546
si:ch211-241j12.3
chr13_+_969851 2.97 ENSDART00000139560
protein phosphatase 3, regulatory subunit B, alpha a
KN149861v1_-_6089 2.79

KN149861v1_-_6661 2.76

chr22_-_21021942 2.73 ENSDART00000133982
single stranded DNA binding protein 4
chr7_-_19116999 2.70 ENSDART00000165680
netrin 4
chr10_-_4641624 2.66 ENSDART00000163951
phospholipid phosphatase related 1
chr25_+_21001126 2.66 ENSDART00000079012
RAD52 homolog, DNA repair protein
chr25_+_16259634 2.64 ENSDART00000136454
TEA domain family member 1a
chr8_-_26690715 2.63 ENSDART00000135215
transmembrane protein 51a
chr15_-_33669618 2.61 ENSDART00000161151
StAR-related lipid transfer (START) domain containing 13b
chr16_-_29452509 2.51 ENSDART00000148787
S100 calcium binding protein A1
chr22_+_866803 2.50 ENSDART00000140588
serine/threonine kinase 38b
chr17_-_52233071 2.49

chr24_+_41991604 2.46

chr24_-_7534334 2.46

chr23_+_19728953 2.43 ENSDART00000104441
abhydrolase domain containing 6b
KN150349v1_-_1437 2.42

chr15_-_5913264 2.38 ENSDART00000155156
ENSDART00000155971
si:ch73-281n10.2
chr7_-_73613531 2.38 ENSDART00000128137
zgc:92594
chr5_-_56641061 2.38 ENSDART00000050957
fer (fps/fes related) tyrosine kinase
chr17_-_45021393 2.37

chr22_-_111800 2.37 ENSDART00000163198
ENSDART00000168678
capping protein (actin filament) muscle Z-line, beta
chr18_-_26732762 2.37 ENSDART00000142043
MALT paracaspase 3
chr5_-_56641212 2.36 ENSDART00000050957
fer (fps/fes related) tyrosine kinase
chr16_-_39655528 2.35 ENSDART00000146301
transforming growth factor beta receptor 2b
chr15_+_25554119 2.34 ENSDART00000162482
zgc:152863
chr2_-_44330306 2.34 ENSDART00000111246
cell adhesion molecule 3
chr20_-_50089784 2.32 ENSDART00000058858
kinesin family member 13Bb
chr22_-_11817641 2.32 ENSDART00000000192
protein tyrosine phosphatase, non-receptor type 4b
chr20_+_37891739 2.31 ENSDART00000022060
activating transcription factor 3
chr7_-_73890600 2.31 ENSDART00000164992
RNA binding protein with multiple splicing
chr13_-_15662476 2.31 ENSDART00000145914
ENSDART00000010286
BCL2-associated athanogene 5
chr6_+_41506350 2.29 ENSDART00000136538
cytokine inducible SH2-containing protein
chr6_+_41506220 2.24 ENSDART00000136538
cytokine inducible SH2-containing protein
chr22_-_11817587 2.24 ENSDART00000000192
protein tyrosine phosphatase, non-receptor type 4b
chr19_+_14132473 2.24 ENSDART00000164696
transmembrane protein 222b
chr23_+_25062876 2.23 ENSDART00000145307
ENSDART00000172299
Rho GTPase activating protein 4a
chr7_-_61373495 2.19 ENSDART00000098622
leucine-rich repeats and calponin homology (CH) domain containing 4
chr13_-_15662599 2.18 ENSDART00000145914
ENSDART00000010286
BCL2-associated athanogene 5
chr7_-_73890499 2.15 ENSDART00000164992
RNA binding protein with multiple splicing
chr19_+_14132374 2.15 ENSDART00000164696
transmembrane protein 222b
chr8_-_3974320 2.13 ENSDART00000159895
myotubularin related protein 3
chr7_-_64745132 2.12 ENSDART00000112166
family with sequence similarity 60, member A, like
chr17_+_14957568 2.12 ENSDART00000066604
G protein-coupled receptor 137c
chr5_-_29480173 2.10 ENSDART00000140049
beta-carotene oxygenase 2a
chr1_-_44907320 2.09

chr7_-_19080002 2.08 ENSDART00000166121
ENSDART00000169668
dedicator of cytokinesis 11
chr6_+_41506504 2.07 ENSDART00000084861
cytokine inducible SH2-containing protein
chr16_-_34471672 2.06 ENSDART00000172162
ENSDARG00000105308
chr24_-_38197984 2.06 ENSDART00000078998
C-reactive protein 2
chr7_+_71263100 2.04 ENSDART00000100396
protein phosphatase 1, regulatory subunit 15A
chr7_+_13742576 2.03

KN150589v1_-_5785 2.02 ENSDART00000157761
ENSDART00000157531
ELOVL fatty acid elongase 7b
chr19_+_26756510 2.01 ENSDART00000013497
myosin regulatory light chain interacting protein a
KN149861v1_-_5543 2.01

chr19_+_14490203 2.00 ENSDART00000164386
AT rich interactive domain 1Ab (SWI-like)
chr23_-_14118530 2.00 ENSDART00000139406
glucose-6-phosphate dehydrogenase
chr18_+_46153484 1.99 ENSDART00000015034
biliverdin reductase B
chr5_-_22466262 1.99 ENSDART00000172549
si:dkey-237j10.2
chr22_-_21873054 1.98

chr3_+_51430252 1.98 ENSDART00000159493
BAI1-associated protein 2a
chr3_-_58400454 1.98 ENSDART00000052179
cerebellar degeneration-related protein 2a
chr15_+_29092022 1.98 ENSDART00000141164
si:ch211-137a8.2
chr22_+_26840517 1.97 ENSDART00000158756
CREB binding protein a
chr8_-_410293 1.95 ENSDART00000164886
tripartite motif containing 36
chr7_+_1443102 1.94 ENSDART00000172830
SPT16 homolog, facilitates chromatin remodeling subunit
chr2_+_44659334 1.94 ENSDART00000155017
PAS domain containing serine/threonine kinase
chr22_-_35003371 1.91 ENSDART00000133537
Rho GTPase activating protein 19
chr22_-_10722533 1.90 ENSDART00000081191
SAS-6 centriolar assembly protein
chr17_+_30476515 1.87

chr17_+_11921705 1.87 ENSDART00000155329
consortin, connexin sorting protein a
chr12_+_46641510 1.87 ENSDART00000008009
tripartite motif containing 16
chr15_-_33669589 1.86 ENSDART00000161151
StAR-related lipid transfer (START) domain containing 13b
chr19_-_5142209 1.84 ENSDART00000150980
chromodomain helicase DNA binding protein 4a
KN149861v1_-_6916 1.81 ENSDART00000169003
5.8S ribosomal RNA
chr21_+_10485148 1.81 ENSDART00000165070
collagen and calcium binding EGF domains 1
chr23_+_35327492 1.80 ENSDART00000164658
si:ch211-225h24.2
chr6_+_41506446 1.80 ENSDART00000140108
cytokine inducible SH2-containing protein
chr16_-_52847564 1.80 ENSDART00000147236
antizyme inhibitor 1a
chr13_-_17729510 1.80 ENSDART00000170583
membrane-associated ring finger (C3HC4) 8
chr2_-_52956254 1.78 ENSDART00000044411
guanine nucleotide binding protein (G protein), alpha 11b (Gq class)
chr7_-_73613763 1.78 ENSDART00000128137
zgc:92594
chr11_+_33154781 1.77

chr16_+_25344184 1.77 ENSDART00000058938
F-box protein 32
chr7_-_19080041 1.77 ENSDART00000137575
dedicator of cytokinesis 11
chr23_-_42918086 1.77 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr19_-_6274169 1.75 ENSDART00000140347
ENSDART00000092656
Ets2 repressor factor
chr5_-_56641001 1.73 ENSDART00000149855
fer (fps/fes related) tyrosine kinase
chr15_-_18087085 1.73 ENSDART00000155194
pleckstrin homology-like domain, family B, member 1b
chr17_+_12788541 1.73 ENSDART00000016597
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b
chr25_+_22222336 1.72 ENSDART00000154065
cytochrome P450, family 11, subfamily A, polypeptide 1
chr20_+_4034072 1.72 ENSDART00000092217
tetratricopeptide repeat domain 13
chr19_-_7402329 1.72 ENSDART00000092375
oxidation resistance 1b
chr23_+_25062826 1.71 ENSDART00000172299
Rho GTPase activating protein 4a
chr22_-_20377970 1.70 ENSDART00000010048
mitogen-activated protein kinase kinase 2a
chr17_+_11921923 1.69 ENSDART00000155329
consortin, connexin sorting protein a
chr13_-_44671682 1.68 ENSDART00000099984
glyoxalase 1
chr1_+_23778481 1.68 ENSDART00000176581
family with sequence similarity 160, member A1a
chr20_+_37891795 1.68 ENSDART00000022060
activating transcription factor 3
chr10_-_625501 1.65 ENSDART00000041236
ENSDART00000144882
regulatory factor X, 3 (influences HLA class II expression)
chr3_-_9755642 1.65 ENSDART00000168366
CREB binding protein b
chr2_-_52956344 1.64 ENSDART00000044411
guanine nucleotide binding protein (G protein), alpha 11b (Gq class)
chr14_+_11803542 1.64 ENSDART00000121913
potassium channel tetramerisation domain containing 12b
chr3_+_26682186 1.63 ENSDART00000055537
suppressor of cytokine signaling 1a
chr7_+_71262845 1.63 ENSDART00000100396
protein phosphatase 1, regulatory subunit 15A
chr25_+_4508802 1.60 ENSDART00000021120
protein-glucosylgalactosylhydroxylysine glucosidase
chr19_+_1298795 1.60 ENSDART00000113368
ring finger protein 5
chr24_+_39339095 1.59 ENSDART00000168705
si:ch73-103b11.2
chr8_-_26690680 1.58 ENSDART00000135215
transmembrane protein 51a
chr13_-_31267133 1.58 ENSDART00000008287
phosphoglycerate mutase 1a
chr7_-_61373339 1.57 ENSDART00000148270
leucine-rich repeats and calponin homology (CH) domain containing 4
chr20_+_16274045 1.56 ENSDART00000129633
zyg-11 homolog (C. elegans)
chr1_+_13768098 1.56 ENSDART00000005067
recombination signal binding protein for immunoglobulin kappa J region a
chr19_-_5142238 1.56 ENSDART00000130062
chromodomain helicase DNA binding protein 4a
chr23_+_35327654 1.56 ENSDART00000165034
si:ch211-225h24.2
chr14_+_25950244 1.55 ENSDART00000113804
ENSDART00000159054
coiled-coil domain containing 69
chr15_-_30935719 1.55 ENSDART00000050649
musashi RNA-binding protein 2b
chr7_-_45579815 1.54 ENSDART00000170224
SHC SH2-domain binding protein 1
chr4_-_17364090 1.54 ENSDART00000134467
PARP1 binding protein
chr10_+_384571 1.54 ENSDART00000129757
si:ch211-242f23.8
chr3_+_29338315 1.54 ENSDART00000103592
family with sequence similarity 83, member Fa
chr16_-_39655605 1.54 ENSDART00000146301
transforming growth factor beta receptor 2b
chr15_+_11760631 1.52

chr2_-_52956156 1.51 ENSDART00000044411
guanine nucleotide binding protein (G protein), alpha 11b (Gq class)
chr19_-_7402373 1.51 ENSDART00000092375
oxidation resistance 1b
chr15_-_43283562 1.51 ENSDART00000110352
adaptor-related protein complex 1, sigma 3 subunit, a
chr15_-_17088654 1.50 ENSDART00000154719
ENSDART00000014465
huntingtin interacting protein 1
chr6_+_28001318 1.50 ENSDART00000143974
angiomotin like 2a
chr2_+_12547264 1.49 ENSDART00000169724
zgc:66475
chr2_-_47766563 1.48 ENSDART00000038228
adaptor-related protein complex 1, sigma 3 subunit, b
chr23_+_39454172 1.48 ENSDART00000149819
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr20_-_14885722 1.48 ENSDART00000160481
SUN domain containing ossification factor
chr4_-_4603205 1.47 ENSDART00000130601
ENSDARG00000090401
chr3_-_58400345 1.47 ENSDART00000052179
cerebellar degeneration-related protein 2a
chr16_-_34471475 1.47 ENSDART00000172162
ENSDARG00000105308
chr24_-_38197866 1.46 ENSDART00000078998
C-reactive protein 2
chr6_-_10574082 1.45 ENSDART00000151661
WAS/WASL interacting protein family, member 1b
chr5_-_6054581 1.45

chr22_-_21021984 1.45 ENSDART00000133982
single stranded DNA binding protein 4
KN150593v1_+_10332 1.44

chr2_+_35621136 1.44 ENSDART00000133018
ENSDART00000147278
polo-like kinase 3 (Drosophila)
chr23_-_42918055 1.43 ENSDART00000102328
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
chr3_-_36298676 1.43 ENSDART00000157950
rogdi homolog (Drosophila)
chr22_-_5888816 1.43 ENSDART00000141373
si:rp71-36a1.1
chr1_+_28936288 1.42

chr13_+_291022 1.42 ENSDART00000017854
leucine-rich, glioma inactivated 1a
chr17_+_25314229 1.42 ENSDART00000082319
transmembrane protein 54a
chr10_-_17214368 1.42

chr22_+_818795 1.42 ENSDART00000003325
DENN/MADD domain containing 2Db
chr15_+_40340914 1.41 ENSDART00000063779
EF-hand domain family, member D1
chr13_-_22776767 1.40 ENSDART00000143097
RUN and FYVE domain containing 2
chr2_+_25212281 1.37 ENSDART00000078838
RAB3A, member RAS oncogene family, a
chr14_+_46609215 1.37 ENSDART00000110429
zgc:194285
chr13_-_37043725 1.37

chr5_-_1102450 1.37 ENSDART00000115044
methyl-CpG binding domain protein 2
chr16_-_34471544 1.37 ENSDART00000172162
ENSDARG00000105308
chr19_-_44161951 1.37 ENSDART00000058491
palmitoyl-protein thioesterase 1 (ceroid-lipofuscinosis, neuronal 1, infantile)
chr24_+_41991566 1.37

chr12_-_37274632 1.36 ENSDART00000152951
CDC42 effector protein (Rho GTPase binding) 4b
chr13_-_50053501 1.36 ENSDART00000098209
sirtuin 1
chr23_-_43785497 1.36 ENSDART00000165963
ENSDARG00000102050
chr20_-_54160297 1.35 ENSDART00000153435
protein phosphatase 2, regulatory subunit B', gamma b
chr23_+_27777325 1.35 ENSDART00000134008
limb development membrane protein 1-like
chr24_+_39339391 1.35 ENSDART00000168705
si:ch73-103b11.2
chr22_-_20899539 1.33 ENSDART00000100642
elongation factor RNA polymerase II
chr15_+_29091983 1.33 ENSDART00000141164
si:ch211-137a8.2
chr7_+_13742622 1.33

KN149704v1_-_17031 1.32

chr17_-_53241366 1.31 ENSDART00000171082
exonuclease 3'-5' domain containing 1
chr2_-_52955900 1.30 ENSDART00000044411
guanine nucleotide binding protein (G protein), alpha 11b (Gq class)
chr24_+_37805069 1.30

KN150286v1_-_2942 1.30

chr20_+_46837436 1.29 ENSDART00000145294
ENSDARG00000022260
chr10_-_5023980 1.27 ENSDART00000137853
heterogeneous nuclear ribonucleoprotein D-like
chr5_+_60677040 1.27 ENSDART00000009507
GATS protein-like 2
chr8_+_23144448 1.27 ENSDART00000063057
DnaJ (Hsp40) homolog, subfamily C, member 5aa
chr6_+_12268892 1.26 ENSDART00000171460
serine/threonine kinase 24b (STE20 homolog, yeast)
chr11_-_40239946 1.25 ENSDART00000165394
si:dkeyp-61b2.1
chr18_+_6498590 1.24 ENSDART00000162398
C2 calcium-dependent domain containing 5
chr2_-_44330348 1.24 ENSDART00000111246
cell adhesion molecule 3
chr21_-_1339525 1.23

chr14_+_25950198 1.22 ENSDART00000113804
ENSDART00000159054
coiled-coil domain containing 69
chr16_+_54466704 1.22 ENSDART00000177364
ENSDART00000176635
ENSDARG00000108514
chr19_-_27185558 1.22 ENSDART00000043776
ENSDART00000168777
ENSDART00000159489
proline-rich coiled-coil 2A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
1.5 4.5 GO:0090083 inclusion body assembly(GO:0070841) regulation of inclusion body assembly(GO:0090083)
1.3 6.5 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
1.3 10.0 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
1.2 6.2 GO:0007603 phototransduction, visible light(GO:0007603)
1.0 3.0 GO:1902047 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) positive regulation of polyamine transmembrane transport(GO:1902269)
0.9 3.6 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.8 4.8 GO:0045002 DNA recombinase assembly(GO:0000730) double-strand break repair via single-strand annealing(GO:0045002)
0.8 3.9 GO:0032516 positive regulation of phosphatase activity(GO:0010922) positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.7 8.5 GO:0090309 methylation-dependent chromatin silencing(GO:0006346) positive regulation of chromatin silencing(GO:0031937) regulation of methylation-dependent chromatin silencing(GO:0090308) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.7 2.1 GO:0016119 carotene metabolic process(GO:0016119) carotene catabolic process(GO:0016121) terpene metabolic process(GO:0042214) terpene catabolic process(GO:0046247)
0.7 2.0 GO:0098751 bone cell development(GO:0098751)
0.6 1.8 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.5 2.9 GO:0040016 embryonic cleavage(GO:0040016)
0.5 1.4 GO:0090166 Golgi disassembly(GO:0090166)
0.4 6.1 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.4 1.3 GO:0042754 negative regulation of circadian rhythm(GO:0042754)
0.4 1.2 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.4 1.6 GO:0072149 glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.4 2.3 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.4 1.9 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.4 1.1 GO:0055091 phospholipid homeostasis(GO:0055091)
0.4 1.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.3 1.4 GO:0048790 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.3 3.4 GO:0060876 semicircular canal formation(GO:0060876)
0.3 2.7 GO:0010591 regulation of lamellipodium assembly(GO:0010591) regulation of lamellipodium organization(GO:1902743)
0.3 1.3 GO:0019075 virion assembly(GO:0019068) virus maturation(GO:0019075) multi-organism membrane organization(GO:0044803) viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.3 1.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.3 0.9 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.3 2.4 GO:0046850 regulation of bone remodeling(GO:0046850)
0.3 1.2 GO:0070940 termination of RNA polymerase II transcription(GO:0006369) dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.3 4.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 2.6 GO:0035912 aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.3 1.3 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.3 0.8 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.2 2.0 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 2.9 GO:0070831 basement membrane assembly(GO:0070831)
0.2 2.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.2 0.7 GO:0045601 regulation of endothelial cell differentiation(GO:0045601)
0.2 1.5 GO:0021772 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.2 1.3 GO:1990118 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 5.7 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 1.8 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.2 6.1 GO:0051453 regulation of intracellular pH(GO:0051453)
0.2 1.1 GO:0032366 intracellular sterol transport(GO:0032366)
0.2 0.9 GO:0006561 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 2.0 GO:0031269 pseudopodium organization(GO:0031268) pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.9 GO:0044857 membrane raft assembly(GO:0001765) plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857) caveola assembly(GO:0070836)
0.1 1.9 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.1 0.7 GO:1904325 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) positive regulation of calcium ion transport into cytosol(GO:0010524) positive regulation of release of sequestered calcium ion into cytosol(GO:0051281) regulation of inhibitory G-protein coupled receptor phosphorylation(GO:1904323) positive regulation of inhibitory G-protein coupled receptor phosphorylation(GO:1904325)
0.1 0.9 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 1.4 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.6 GO:0010269 response to selenium ion(GO:0010269)
0.1 0.8 GO:0032534 regulation of microvillus organization(GO:0032530) regulation of microvillus assembly(GO:0032534)
0.1 1.7 GO:0008089 anterograde axonal transport(GO:0008089)
0.1 1.7 GO:0050796 cilium or flagellum-dependent cell motility(GO:0001539) regulation of insulin secretion(GO:0050796) cilium-dependent cell motility(GO:0060285)
0.1 0.8 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.6 GO:0003128 heart field specification(GO:0003128)
0.1 0.3 GO:0046661 development of primary male sexual characteristics(GO:0046546) male sex differentiation(GO:0046661)
0.1 1.4 GO:0002084 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.1 0.4 GO:0010990 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 1.2 GO:0097499 protein localization to nonmotile primary cilium(GO:0097499)
0.1 1.5 GO:0006265 DNA topological change(GO:0006265)
0.1 1.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.3 GO:0071364 response to epidermal growth factor(GO:0070849) cellular response to epidermal growth factor stimulus(GO:0071364)
0.1 4.0 GO:0009615 response to virus(GO:0009615)
0.1 0.9 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.1 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 4.7 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 0.5 GO:0050805 negative regulation of synaptic transmission(GO:0050805) negative regulation of neurotransmitter transport(GO:0051589)
0.1 1.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.8 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 3.9 GO:0030336 negative regulation of cell migration(GO:0030336)
0.1 0.9 GO:0042026 protein refolding(GO:0042026)
0.1 0.9 GO:0060998 regulation of dendritic spine development(GO:0060998)
0.1 0.9 GO:0048016 calcineurin-NFAT signaling cascade(GO:0033173) inositol phosphate-mediated signaling(GO:0048016)
0.1 0.4 GO:0007063 regulation of sister chromatid cohesion(GO:0007063) regulation of cohesin loading(GO:0071922)
0.1 0.8 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.3 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.0 GO:0090481 pyrimidine nucleotide-sugar transport(GO:0015781) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 2.2 GO:0000187 activation of MAPK activity(GO:0000187)
0.1 4.2 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179) response to transforming growth factor beta(GO:0071559) cellular response to transforming growth factor beta stimulus(GO:0071560)
0.1 0.5 GO:0060036 notochord cell vacuolation(GO:0060036)
0.1 0.6 GO:0042430 indole-containing compound metabolic process(GO:0042430) phenol-containing compound biosynthetic process(GO:0046189)
0.1 3.5 GO:0009617 response to bacterium(GO:0009617)
0.1 0.7 GO:0051310 metaphase plate congression(GO:0051310)
0.1 2.0 GO:0030048 actin filament-based movement(GO:0030048)
0.1 0.9 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 0.5 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.1 1.4 GO:0007131 reciprocal meiotic recombination(GO:0007131)
0.0 3.4 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.0 2.5 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 4.0 GO:0006954 inflammatory response(GO:0006954)
0.0 0.5 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.8 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 2.0 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.0 GO:0035329 hippo signaling(GO:0035329)
0.0 4.0 GO:0016573 histone acetylation(GO:0016573)
0.0 2.1 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.9 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.2 GO:0045950 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247) negative regulation of mitotic recombination(GO:0045950)
0.0 0.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.6 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.0 1.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.3 GO:0006970 response to osmotic stress(GO:0006970)
0.0 2.9 GO:0006979 response to oxidative stress(GO:0006979)
0.0 1.0 GO:0021591 ventricular system development(GO:0021591)
0.0 0.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.6 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.0 1.7 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 1.7 GO:0042552 ensheathment of neurons(GO:0007272) axon ensheathment(GO:0008366) myelination(GO:0042552)
0.0 0.3 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.4 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 1.0 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 0.8 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 1.4 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.5 GO:0060972 left/right pattern formation(GO:0060972)
0.0 2.1 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 0.8 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 1.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.5 GO:0051051 negative regulation of transport(GO:0051051)
0.0 0.6 GO:0070121 Kupffer's vesicle development(GO:0070121)
0.0 0.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0098536 deuterosome(GO:0098536)
0.6 1.8 GO:0043291 RAVE complex(GO:0043291)
0.5 6.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.4 1.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 1.7 GO:0008290 F-actin capping protein complex(GO:0008290)
0.3 1.6 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.3 0.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.3 1.9 GO:0035101 FACT complex(GO:0035101)
0.3 2.9 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 4.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 2.5 GO:0035060 brahma complex(GO:0035060)
0.2 3.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 10.0 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.1 13.5 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.1 1.7 GO:0045180 basal cortex(GO:0045180)
0.1 1.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.1 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 1.3 GO:0000813 ESCRT I complex(GO:0000813)
0.1 4.0 GO:0016605 PML body(GO:0016605)
0.1 7.1 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 1.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.8 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 3.1 GO:0030175 filopodium(GO:0030175)
0.1 2.2 GO:0005844 polysome(GO:0005844)
0.1 0.3 GO:0071065 alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065)
0.1 0.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 4.9 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 0.3 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.1 0.6 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.3 GO:0043186 P granule(GO:0043186)
0.1 0.6 GO:0030667 secretory granule membrane(GO:0030667)
0.1 0.3 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 4.5 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 4.0 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 5.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 3.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.4 GO:0098978 glutamatergic synapse(GO:0098978)
0.0 2.3 GO:0005871 kinesin complex(GO:0005871)
0.0 0.3 GO:0089701 U2AF(GO:0089701)
0.0 2.8 GO:0048475 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 2.1 GO:0000922 spindle pole(GO:0000922)
0.0 2.9 GO:0005884 actin filament(GO:0005884)
0.0 1.1 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.2 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.2 GO:0005930 axoneme(GO:0005930)
0.0 1.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.2 GO:0070187 telosome(GO:0070187)
0.0 1.0 GO:0030173 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.0 1.8 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.9 GO:0000776 kinetochore(GO:0000776)
0.0 0.3 GO:0043296 apical junction complex(GO:0043296)
0.0 1.4 GO:0005764 lysosome(GO:0005764)
0.0 0.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
1.3 3.9 GO:0034713 transforming growth factor beta receptor activity, type II(GO:0005026) type I transforming growth factor beta receptor binding(GO:0034713)
1.1 3.3 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity(GO:0008118)
1.0 3.0 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.8 7.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.7 2.1 GO:0010436 beta-carotene 15,15'-monooxygenase activity(GO:0003834) carotenoid dioxygenase activity(GO:0010436)
0.6 1.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.5 3.6 GO:0071253 connexin binding(GO:0071253)
0.5 6.5 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.3 10.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.3 4.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 4.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.3 0.9 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.3 1.6 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.2 1.4 GO:0015616 DNA translocase activity(GO:0015616)
0.2 4.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 1.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.2 1.3 GO:0015385 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 5.7 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 3.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 0.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 0.8 GO:0004630 phospholipase D activity(GO:0004630)
0.2 0.8 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 3.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 1.5 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 0.5 GO:0016882 cyclo-ligase activity(GO:0016882)
0.2 2.5 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 0.8 GO:0042287 MHC protein binding(GO:0042287)
0.2 1.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 2.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 2.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.6 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 1.0 GO:0043495 protein anchor(GO:0043495)
0.1 0.7 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.1 1.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 3.4 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 0.7 GO:0060182 apelin receptor activity(GO:0060182)
0.1 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 0.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 1.6 GO:0015926 glucosidase activity(GO:0015926)
0.1 3.7 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.4 GO:0070403 NAD+ binding(GO:0070403)
0.1 1.0 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.3 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 4.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 1.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 1.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.1 5.8 GO:0031491 nucleosome binding(GO:0031491)
0.1 1.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.3 GO:0033204 ribonuclease P RNA binding(GO:0033204)
0.1 0.8 GO:0001130 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.1 1.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.3 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.1 1.1 GO:0008143 poly(A) binding(GO:0008143)
0.1 0.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.1 1.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 0.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.9 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.8 GO:0004698 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698)
0.0 1.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 2.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.4 GO:0044390 ubiquitin conjugating enzyme binding(GO:0031624) ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.5 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.7 GO:0034061 DNA-directed DNA polymerase activity(GO:0003887) DNA polymerase activity(GO:0034061)
0.0 4.1 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)
0.0 3.3 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.8 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 1.3 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.5 GO:0030276 clathrin binding(GO:0030276)
0.0 0.3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 8.1 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 3.9 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 3.1 GO:0003682 chromatin binding(GO:0003682)
0.0 0.5 GO:0005347 ATP transmembrane transporter activity(GO:0005347)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 8.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.5 2.0 ST STAT3 PATHWAY STAT3 Pathway
0.2 11.1 PID FOXO PATHWAY FoxO family signaling
0.2 6.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 0.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 3.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 3.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 3.7 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 3.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 3.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.7 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 1.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.5 4.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.4 4.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.4 8.4 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.2 4.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 2.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 3.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.9 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 3.3 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 5.9 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.1 1.1 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 1.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.7 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 3.1 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.1 0.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 0.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.9 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 8.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 1.0 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling