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Results for srfa+srfb

Z-value: 3.12

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Transcription factors associated with srfa+srfb

Gene Symbol Gene ID Gene Info
srfa
ENSDARG00000053918 serum response factor a
srfb
ENSDARG00000102867 serum response factor b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
srfadr10_dc_chr22_+_35113233_351133700.845.4e-05Click!

Activity profile of srfa+srfb motif

Sorted Z-values of srfa+srfb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of srfa+srfb

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr1_+_53286155 16.95 ENSDART00000139625
acta1a
actin, alpha 1a, skeletal muscle
chr7_+_29680967 15.65 ENSDART00000173540
tpma
alpha-tropomyosin
chr20_-_9992898 14.87 ENSDART00000080664
ACTC1
zgc:86709
chr5_-_31708933 14.37 ENSDART00000123003
myhz1.1
myosin, heavy polypeptide 1.1, skeletal muscle
chr5_-_31674204 14.24 ENSDART00000122889
myhz1.3
myosin, heavy polypeptide 1.3, skeletal muscle
chr14_-_21039158 14.01 ENSDART00000054460
egr1
early growth response 1
chr13_+_24148599 13.50 ENSDART00000058629
acta1b
actin, alpha 1b, skeletal muscle
chr5_+_36487425 12.42 ENSDART00000049900
tagln2
transgelin 2
chr20_-_29517770 12.28 ENSDART00000147464
ryr3
ryanodine receptor 3
chr11_+_6118409 10.66 ENSDART00000027666
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr8_-_11191783 10.32 ENSDART00000131171
unc45b
unc-45 myosin chaperone B
chr12_-_25973094 9.10 ENSDART00000171206
ENSDART00000171212
ENSDART00000170265
ldb3b
LIM domain binding 3b
chr5_-_31692803 8.93 ENSDART00000131983
myhz1.2
myosin, heavy polypeptide 1.2, skeletal muscle
chr2_+_30932612 8.05 ENSDART00000132450
ENSDART00000137012
myom1a
myomesin 1a (skelemin)
chr12_+_42281025 7.95 ENSDART00000167324
ebf3a
early B-cell factor 3a
chr22_-_36915567 7.94 ENSDART00000029588
kng1
kininogen 1
chr10_+_6316944 7.72 ENSDART00000162428
tpm2
tropomyosin 2 (beta)
chr3_+_23577103 7.64 ENSDART00000025449
hoxb5a
homeobox B5a
chr5_+_49093250 7.34 ENSDART00000133384
nr2f1a
nuclear receptor subfamily 2, group F, member 1a
chr2_-_24898678 7.26 ENSDART00000145145
cnn2
calponin 2
chr6_-_39315024 7.17 ENSDART00000012644
krt4
keratin 4
chr19_-_6384776 7.04

chr13_-_3022033 6.80 ENSDART00000050934
pkdcca
protein kinase domain containing, cytoplasmic a
chr5_+_49093134 6.79 ENSDART00000133384
nr2f1a
nuclear receptor subfamily 2, group F, member 1a
chr1_+_51925783 6.69 ENSDART00000167514
abca1a
ATP-binding cassette, sub-family A (ABC1), member 1A
chr1_+_1657493 6.57 ENSDART00000103850
atp1a1a.3
ATPase, Na+/K+ transporting, alpha 1a polypeptide, tandem duplicate 3
chr21_+_25729090 6.56 ENSDART00000021664
cldnb
claudin b
chr20_-_42805703 6.36 ENSDART00000045816
plg
plasminogen
chr18_-_23889256 6.06 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr20_+_14979154 5.91 ENSDART00000118157
dre-mir-199-1
dre-mir-199-1
chr7_-_71566426 5.84 ENSDART00000166724
myom1b
myomesin 1b
chr14_+_45895103 5.81

chr16_+_53178713 5.76 ENSDART00000174634
CABZ01062546.1
ENSDARG00000108858
chr9_-_47833777 5.76

chr8_+_20125687 5.20 ENSDART00000124809
acsbg2
acyl-CoA synthetase bubblegum family member 2
chr1_-_50147413 5.17 ENSDART00000080389
fam13a
family with sequence similarity 13, member A
chr14_+_34174018 5.16 ENSDART00000024440
foxi3b
forkhead box I3b
chr12_+_19240407 5.04 ENSDART00000041711
gspt1
G1 to S phase transition 1
chr11_+_6118322 4.86 ENSDART00000165031
nr2f6b
nuclear receptor subfamily 2, group F, member 6b
chr22_-_15576473 4.82 ENSDART00000036075
tpm4a
tropomyosin 4a
chr2_-_55879949 4.80 ENSDART00000140309
cplx4c
complexin 4c
chr23_+_42920817 4.78 ENSDART00000055577
myl9a
myosin, light chain 9a, regulatory
chr9_-_47833718 4.77

chr7_-_28278286 4.71 ENSDART00000113313
st5
suppression of tumorigenicity 5
chr20_+_40247918 4.70 ENSDART00000121818
trdn
triadin
chr20_+_35377079 4.68 ENSDART00000168216
fam49a
family with sequence similarity 49, member A
chr13_+_29108288 4.63 ENSDART00000026000
myofl
myoferlin like
chr21_+_6858073 4.53 ENSDART00000139493
olfm1b
olfactomedin 1b
chr23_-_7283514 4.38 ENSDART00000156369
CR589876.1
ENSDARG00000096997
chr6_-_18733424 4.37 ENSDART00000151578
tns1a
tensin 1a
chr18_-_23888988 4.25 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr13_-_3022193 4.19 ENSDART00000050934
pkdcca
protein kinase domain containing, cytoplasmic a
chr5_+_37861949 4.18 ENSDART00000144425
gltpd2
glycolipid transfer protein domain containing 2
chr18_+_35433242 4.17 ENSDART00000057733
zgc:153119
zgc:153119
chr24_+_31340115 4.16 ENSDART00000165993
f3a
coagulation factor IIIa
chr18_-_23889025 4.13 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr2_-_24614261 4.11 ENSDART00000099532
vmhc
ventricular myosin heavy chain
chr21_-_17566461 3.94 ENSDART00000044078
ENSDART00000168495
ENSDART00000020048
gsna
gelsolin a
chr13_-_3022131 3.82 ENSDART00000050934
pkdcca
protein kinase domain containing, cytoplasmic a
chr22_-_36915720 3.79 ENSDART00000029588
kng1
kininogen 1
chr25_+_32707410 3.78 ENSDART00000125892
ENSDART00000121680
ENSDARG00000087402
ENSDARG00000087402
chr7_-_52848084 3.77 ENSDART00000172179
ENSDART00000167882
cdh1
cadherin 1, type 1, E-cadherin (epithelial)
chr23_-_10241885 3.77 ENSDART00000081223
ENSDART00000144280
krt5
keratin 5
chr3_-_35472632 3.77 ENSDART00000055269
gng13b
guanine nucleotide binding protein (G protein), gamma 13b
chr13_+_24148474 3.76 ENSDART00000058629
acta1b
actin, alpha 1b, skeletal muscle
chr24_+_40292617 3.64

chr23_+_36019989 3.63 ENSDART00000103134
ENSDART00000139319
hoxc5a
homeobox C5a
chr16_+_28449134 3.61 ENSDART00000059044
itga8
integrin, alpha 8
chr12_+_27038210 3.58 ENSDART00000076161
hoxb5b
homeobox B5b
chr20_+_20287015 3.49 ENSDART00000002507
rhoj
ras homolog family member J
chr8_+_50738477 3.36 ENSDART00000127062
egr3
early growth response 3
chr18_-_23889169 3.35 ENSDART00000059976
nr2f2
nuclear receptor subfamily 2, group F, member 2
chr19_+_32679320 3.31

chr1_-_5796394 3.25 ENSDART00000109356
klf7a
Kruppel-like factor 7a
chr19_+_32679258 3.07

chr7_+_5372830 3.03 ENSDART00000135271
MYADM
myeloid associated differentiation marker
chr22_-_29387056 3.00 ENSDART00000121599
pdgfba
platelet-derived growth factor beta polypeptide a
chr10_-_42157835 2.97 ENSDART00000141500
ENSDART00000156626
BX005309.1
ENSDARG00000093535
chr16_+_12740993 2.95 ENSDART00000128497
nat14
N-acetyltransferase 14 (GCN5-related, putative)
chr22_+_35113233 2.94 ENSDART00000123066
srfa
serum response factor a
chr12_+_27038298 2.93 ENSDART00000076161
hoxb5b
homeobox B5b
chr17_-_20098393 2.90 ENSDART00000165606
ryr2b
ryanodine receptor 2b (cardiac)
chr2_+_24718602 2.89 ENSDART00000022379
nr2f6a
nuclear receptor subfamily 2, group F, member 6a
chr23_+_36019758 2.84 ENSDART00000103134
ENSDART00000139319
hoxc5a
homeobox C5a
chr9_-_39190534 2.76

chr5_+_69401770 2.74

chr10_+_44509370 2.68

chr10_-_44509732 2.66

chr5_+_35198499 2.53

chr14_-_25011874 2.49 ENSDART00000159569
htr4
5-hydroxytryptamine receptor 4
chr17_-_42778156 2.49 ENSDART00000140549
nkx2.2a
NK2 homeobox 2a
chr5_-_54773058 2.48 ENSDART00000145791
prune2
prune homolog 2 (Drosophila)
KN150015v1_+_1935 2.40 ENSDART00000169907
ENSDART00000160155
PDCL3
phosducin like 3
chr20_+_53772078 2.28 ENSDART00000126983
myh6
myosin, heavy chain 6, cardiac muscle, alpha
chr19_-_34328673 2.27 ENSDART00000164563
elmo1
engulfment and cell motility 1 (ced-12 homolog, C. elegans)
chr7_+_29681196 2.21 ENSDART00000039657
tpma
alpha-tropomyosin
chr20_+_14978952 2.13 ENSDART00000118157
dre-mir-199-1
dre-mir-199-1
chr7_+_29680933 2.12 ENSDART00000173540
tpma
alpha-tropomyosin
chr22_-_18520027 2.12 ENSDART00000132156
cirbpb
cold inducible RNA binding protein b
chr10_-_29930133 2.10 ENSDART00000055913
hist2h2l
histone 2, H2, like
chr20_+_6600246 2.10 ENSDART00000136567
tns3.2
tensin 3, tandem duplicate 2
chr2_-_55879979 2.10 ENSDART00000150179
cplx4c
complexin 4c
chr3_-_22098046 2.00 ENSDART00000017750
myl4
myosin, light chain 4, alkali; atrial, embryonic
chr17_-_20959288 2.00 ENSDART00000006676
phyhipla
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr12_+_42281154 1.99 ENSDART00000167324
ebf3a
early B-cell factor 3a
chr20_-_2936289 1.98 ENSDART00000104667
cdk19
cyclin-dependent kinase 19
chr10_-_1690605 1.93 ENSDART00000137620
si:ch73-46j18.5
si:ch73-46j18.5
chr5_-_70991958 1.88 ENSDART00000011955
ENSDART00000160380
gpsm1b
G protein signaling modulator 1b
chr21_+_6858020 1.88 ENSDART00000139493
olfm1b
olfactomedin 1b
chr20_+_6600184 1.62 ENSDART00000136567
tns3.2
tensin 3, tandem duplicate 2
chr4_-_16655742 1.55 ENSDART00000042307
fam60a
family with sequence similarity 60, member A
chr3_-_40387858 1.40 ENSDART00000055194
actb2
actin, beta 2
chr11_-_11722452 1.39 ENSDART00000161293
CR848705.2
ENSDARG00000104692
chr22_-_15576405 1.39 ENSDART00000009054
tpm4a
tropomyosin 4a
chr12_+_16978590 1.38 ENSDART00000177923
acta2
actin, alpha 2, smooth muscle, aorta
chr17_-_8498935 1.37 ENSDART00000148990
ctbp2a
C-terminal binding protein 2a
chr20_-_48255596 1.33 ENSDART00000031167
tfap2d
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr14_+_45895037 1.32

chr3_+_58096720 1.32 ENSDART00000010395
ENSDART00000159755
ENSDART00000171149
uqcrc2a
ubiquinol-cytochrome c reductase core protein IIa
chr22_-_36915689 1.29 ENSDART00000029588
kng1
kininogen 1
chr20_+_54544931 1.26

chr20_+_40248154 1.22 ENSDART00000121818
trdn
triadin
chr21_-_2597493 1.22

chr11_+_16018035 1.19 ENSDART00000081054
tada3l
transcriptional adaptor 3 (NGG1 homolog, yeast)-like
chr7_+_71572830 1.14 ENSDART00000171996
myl12.1
myosin, light chain 12, genome duplicate 1
chr20_+_35377155 1.09 ENSDART00000147320
ENSDART00000131974
fam49a
family with sequence similarity 49, member A
chr3_-_51038166 1.06

chr9_+_6609374 1.04 ENSDART00000122279
fhl2a
four and a half LIM domains 2a
chr16_-_30463239 1.03 ENSDART00000003752
cct3
chaperonin containing TCP1, subunit 3 (gamma)
chr12_-_8633437 1.02

chr2_-_49149839 0.98

chr5_-_31708973 0.96 ENSDART00000123003
myhz1.1
myosin, heavy polypeptide 1.1, skeletal muscle
chr15_-_39783178 0.89

chr1_-_7968497 0.84 ENSDART00000141407
ENSDART00000148067
actb1
actin, beta 1
chr14_+_4169371 0.69 ENSDART00000136665
gnpda2
glucosamine-6-phosphate deaminase 2
chr20_+_37963275 0.64 ENSDART00000153190
vash2
vasohibin 2
chr19_+_7630847 0.60 ENSDART00000151758
pbxip1a
pre-B-cell leukemia homeobox interacting protein 1a
chr7_-_28278230 0.56 ENSDART00000054368
st5
suppression of tumorigenicity 5
chr22_+_33408025 0.52 ENSDART00000101580
nicn1
nicolin 1
chr12_-_26759201 0.52

chr23_+_36020128 0.52 ENSDART00000103134
ENSDART00000139319
hoxc5a
homeobox C5a
chr19_+_46567459 0.51 ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr23_+_36019942 0.51 ENSDART00000103134
ENSDART00000139319
hoxc5a
homeobox C5a
chr2_+_56045488 0.49 ENSDART00000021011
upf1
upf1 regulator of nonsense transcripts homolog (yeast)
chr14_+_300285 0.43 ENSDART00000159949
wdr1
WD repeat domain 1
chr13_+_24148390 0.28 ENSDART00000058629
acta1b
actin, alpha 1b, skeletal muscle
chr10_+_8143021 0.22 ENSDART00000138875
pstpip2
proline-serine-threonine phosphatase interacting protein 2
chr22_-_18520332 0.21

chr1_-_53081860 0.18 ENSDART00000026409
cct4
chaperonin containing TCP1, subunit 4 (delta)
chr19_+_44120313 0.16 ENSDART00000006344
cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr3_+_51182773 0.16

chr23_-_16765933 0.14 ENSDART00000046784
fkbp1ab
FK506 binding protein 1Ab
chr1_-_7967515 0.10 ENSDART00000133319
actb1
actin, beta 1
chr10_-_1690504 0.06 ENSDART00000137620
si:ch73-46j18.5
si:ch73-46j18.5
chr16_-_2880109 0.03 ENSDART00000149463
hace1
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 17.8 GO:0060845 lymphatic endothelial cell fate commitment(GO:0060838) venous endothelial cell differentiation(GO:0060843) venous endothelial cell fate commitment(GO:0060845)
2.8 19.4 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
2.6 18.3 GO:0072132 mesenchyme morphogenesis(GO:0072132)
1.7 5.2 GO:0009957 epidermal cell fate specification(GO:0009957)
1.5 16.4 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011)
1.1 6.7 GO:0032374 regulation of sterol transport(GO:0032371) regulation of cholesterol transport(GO:0032374)
1.0 5.0 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.8 2.5 GO:0008347 glial cell migration(GO:0008347)
0.7 15.3 GO:0001757 somite specification(GO:0001757)
0.6 2.5 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.6 7.3 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.6 15.2 GO:0051209 release of sequestered calcium ion into cytosol(GO:0051209)
0.5 6.5 GO:0010002 cardioblast differentiation(GO:0010002)
0.5 5.2 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.5 3.8 GO:0007606 sensory perception of chemical stimulus(GO:0007606)
0.4 2.5 GO:0006797 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.4 5.8 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.4 43.0 GO:0006936 muscle contraction(GO:0006936)
0.4 6.6 GO:0030007 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.4 3.0 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.4 14.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.3 1.4 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.3 5.9 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.3 10.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.3 6.9 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.2 2.5 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.1 4.6 GO:0007520 myoblast fusion(GO:0007520)
0.1 8.1 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.1 3.9 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.1 0.7 GO:0006043 glucosamine metabolic process(GO:0006041) glucosamine catabolic process(GO:0006043)
0.1 0.7 GO:0030817 regulation of cAMP metabolic process(GO:0030814) regulation of cAMP biosynthetic process(GO:0030817) regulation of adenylate cyclase activity(GO:0045761)
0.1 7.6 GO:0001708 cell fate specification(GO:0001708)
0.1 17.1 GO:0000122 negative regulation of transcription from RNA polymerase II promoter(GO:0000122)
0.1 2.3 GO:0045766 positive regulation of angiogenesis(GO:0045766)
0.1 3.6 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.0 3.7 GO:0031101 fin regeneration(GO:0031101)
0.0 1.0 GO:2000027 regulation of organ morphogenesis(GO:2000027)
0.0 7.5 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 9.1 GO:0061061 muscle structure development(GO:0061061)
0.0 2.1 GO:0006334 nucleosome assembly(GO:0006334)
0.0 16.8 GO:0006468 protein phosphorylation(GO:0006468)
0.0 7.3 GO:0030036 actin cytoskeleton organization(GO:0030036)
0.0 0.6 GO:0045765 regulation of angiogenesis(GO:0045765)
0.0 0.0 GO:2000378 negative regulation of reactive oxygen species metabolic process(GO:2000378)
0.0 2.9 GO:0045944 positive regulation of transcription from RNA polymerase II promoter(GO:0045944)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.8 35.9 GO:0005869 dynactin complex(GO:0005869)
2.5 15.2 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
1.3 24.2 GO:0031672 A band(GO:0031672)
1.0 5.0 GO:0018444 translation release factor complex(GO:0018444)
0.8 40.8 GO:0016459 myosin complex(GO:0016459)
0.5 2.1 GO:0097433 dense body(GO:0097433)
0.5 42.5 GO:0005884 actin filament(GO:0005884)
0.5 10.2 GO:0045095 keratin filament(GO:0045095)
0.5 6.9 GO:0043195 terminal bouton(GO:0043195)
0.5 5.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.3 2.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 3.6 GO:0008305 integrin complex(GO:0008305)
0.1 1.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 6.6 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 3.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 13.9 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 1.0 GO:0030018 Z disc(GO:0030018)
0.0 2.0 GO:0016592 mediator complex(GO:0016592)
0.0 4.6 GO:0030659 cytoplasmic vesicle membrane(GO:0030659)
0.0 2.1 GO:0000786 nucleosome(GO:0000786)
0.0 16.1 GO:0005576 extracellular region(GO:0005576)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 15.2 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
1.6 17.8 GO:0001972 retinoic acid binding(GO:0001972)
1.1 6.7 GO:0090556 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.7 10.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.7 6.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.6 2.5 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.5 5.2 GO:0016405 CoA-ligase activity(GO:0016405)
0.5 2.1 GO:0098973 structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.5 5.0 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.5 14.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.4 9.1 GO:0051393 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.4 31.2 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.4 2.5 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.4 3.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.3 40.8 GO:0003774 motor activity(GO:0003774)
0.3 13.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 14.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.3 3.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 43.9 GO:0051015 actin filament binding(GO:0051015)
0.1 0.7 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 6.9 GO:0019905 syntaxin binding(GO:0019905)
0.1 2.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.1 18.2 GO:0003779 actin binding(GO:0003779)
0.1 6.4 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.3 GO:0017124 SH3 domain binding(GO:0017124)
0.0 38.7 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 1.4 GO:0051287 NAD binding(GO:0051287)
0.0 6.6 GO:0005198 structural molecule activity(GO:0005198)
0.0 1.2 GO:0051082 unfolded protein binding(GO:0051082)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 13.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
1.2 17.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.5 17.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.4 6.4 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.2 3.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 2.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 3.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
1.6 13.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.8 2.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.6 14.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.6 12.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 19.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.3 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 7.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 1.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+