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Results for tal1

Z-value: 1.09

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Transcription factors associated with tal1

Gene Symbol Gene ID Gene Info
tal1
ENSDARG00000019930 T-cell acute lymphocytic leukemia 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tal1dr10_dc_chr22_+_16509286_165093220.853.1e-05Click!

Activity profile of tal1 motif

Sorted Z-values of tal1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of tal1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_+_9115745 3.15 ENSDART00000123652
hmgn6
high mobility group nucleosome binding domain 6
chr8_-_985673 2.89 ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr2_-_16896965 2.75 ENSDART00000022549
atp1b3a
ATPase, Na+/K+ transporting, beta 3a polypeptide
chr25_+_30699938 2.67 ENSDART00000036275
tnni2a.4
troponin I type 2a (skeletal, fast), tandem duplicate 4
chr25_-_35819345 2.46 ENSDART00000064400
si:ch211-113a14.24
si:ch211-113a14.24
chr11_-_22211478 2.45 ENSDART00000065996
tmem183a
transmembrane protein 183A
chr3_-_58170499 2.32 ENSDART00000074272
im:6904045
im:6904045
chr25_+_31457309 2.31 ENSDART00000022325
parp16
poly (ADP-ribose) polymerase family, member 16
chr7_+_23778570 2.22 ENSDART00000121837
efs
embryonal Fyn-associated substrate
chr16_-_42040346 2.21 ENSDART00000169313
pycard
PYD and CARD domain containing
chr16_+_24057260 2.19 ENSDART00000132742
ENSDART00000145330
apoc1
apolipoprotein C-I
chr14_-_36523075 2.12 ENSDART00000109293
rnf130
ring finger protein 130
chr1_+_27174549 2.12 ENSDART00000102337
dnajb14
DnaJ (Hsp40) homolog, subfamily B, member 14
chr23_+_565406 2.10 ENSDART00000055134
ogfr
opioid growth factor receptor
chr24_-_26165778 2.07 ENSDART00000080113
apodb
apolipoprotein Db
chr9_+_308260 2.06 ENSDART00000163474
stac3
SH3 and cysteine rich domain 3
chr20_+_2443682 1.98 ENSDART00000131642
akap7
A kinase (PRKA) anchor protein 7
chr17_-_9917832 1.96 ENSDART00000161574
ENSDART00000166081
zgc:109986
zgc:109986
chr21_+_27346176 1.92 ENSDART00000005682
actn3a
actinin alpha 3a
chr17_+_135165 1.90 ENSDART00000166339
klhdc2
kelch domain containing 2
chr5_+_40722565 1.89 ENSDART00000097546
arid3c
AT rich interactive domain 3C (BRIGHT-like)
chr2_-_42784609 1.84

chr22_+_33177432 1.77 ENSDART00000126885
dag1
dystroglycan 1
chr9_+_51693805 1.75 ENSDART00000132896
fap
fibroblast activation protein, alpha
chr1_+_51925783 1.68 ENSDART00000167514
abca1a
ATP-binding cassette, sub-family A (ABC1), member 1A
chr3_-_1463509 1.67 ENSDART00000053892
ENSDARG00000074266
ENSDARG00000074266
chr22_-_26333957 1.65 ENSDART00000130493
capn2b
calpain 2, (m/II) large subunit b
chr25_+_182037 1.65 ENSDART00000156469
RPS17
ribosomal protein S17
chr16_+_22950567 1.64 ENSDART00000143957
flad1
flavin adenine dinucleotide synthetase 1
chr17_+_53068731 1.61 ENSDART00000156774
dph6
diphthamine biosynthesis 6
chr8_-_23172938 1.56 ENSDART00000141090
si:ch211-196c10.15
si:ch211-196c10.15
chr25_-_34648956 1.56 ENSDART00000154851
zgc:153405
zgc:153405
chr22_+_26543146 1.56

chr17_+_53224434 1.53 ENSDART00000166517
asb2b
ankyrin repeat and SOCS box containing 2b
chr23_+_36822250 1.53

chr12_-_25825072 1.53

KN150475v1_-_1819 1.52

chr3_+_54327353 1.52 ENSDART00000127487
eif3g
eukaryotic translation initiation factor 3, subunit G
chr7_+_6517248 1.52 ENSDART00000102681
pnp5a
purine nucleoside phosphorylase 5a
chr25_+_34545289 1.51 ENSDART00000126625
si:dkey-108k21.10
si:dkey-108k21.10
chr22_-_120677 1.48

KN149858v1_-_12281 1.47 ENSDART00000157456
CABZ01056637.1
ENSDARG00000100203
chr4_+_8637319 1.46

chr9_+_16437408 1.43 ENSDART00000006787
epha3
eph receptor A3
chr16_+_55167489 1.41 ENSDART00000149795
nr0b2a
nuclear receptor subfamily 0, group B, member 2a
chr14_-_8975187 1.36 ENSDART00000054693
asb12b
ankyrin repeat and SOCS box-containing 12b
chr3_-_29846530 1.36 ENSDART00000077111
hsd17b14
hydroxysteroid (17-beta) dehydrogenase 14
chr16_+_54751779 1.32

chr6_-_51573878 1.31 ENSDART00000166911
rbl1
retinoblastoma-like 1 (p107)
chr22_+_34738389 1.30 ENSDART00000154372
hoga1
4-hydroxy-2-oxoglutarate aldolase 1
chr7_-_6334472 1.30 ENSDART00000081359
zgc:110425
zgc:110425
chr3_-_25886553 1.29 ENSDART00000030890
hmox1a
heme oxygenase 1a
chr24_-_26138298 1.27 ENSDART00000128618
and1
actinodin1
chr19_+_31817286 1.27 ENSDART00000078459
tmem55a
transmembrane protein 55A
chr16_-_41553835 1.24 ENSDART00000029492
cmtm7
CKLF-like MARVEL transmembrane domain containing 7
chr15_+_29343644 1.24 ENSDART00000170537
ENSDART00000128973
rap1gap2a
RAP1 GTPase activating protein 2a
chr14_-_46648563 1.22

chr1_-_23765358 1.22

chr10_+_4987494 1.21 ENSDART00000121959
si:ch73-234b20.5
si:ch73-234b20.5
chr4_-_5294280 1.20 ENSDART00000178921
SNAP91 (1 of many)
si:ch211-214j24.9
chr19_-_24971633 1.19 ENSDART00000162801
polr3gla
polymerase (RNA) III (DNA directed) polypeptide G like a
chr16_+_5625301 1.17

chr16_+_3090170 1.17 ENSDART00000110395
limd1a
LIM domains containing 1a
chr3_-_6922655 1.17

chr14_+_28126921 1.17 ENSDART00000026846
pin4
protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)
KN149932v1_+_27584 1.16

chr7_+_32451041 1.15 ENSDART00000126565
si:ch211-150g13.3
si:ch211-150g13.3
chr3_+_6150498 1.13 ENSDART00000175915
BX284638.2
ENSDARG00000108888
chr14_-_25279835 1.13 ENSDART00000163669
cplx2
complexin 2
chr6_+_4712785 1.12 ENSDART00000151674
pcdh9
protocadherin 9
chr11_-_80746 1.12

chr19_-_22182031 1.11 ENSDART00000104279
znf516
zinc finger protein 516
chr21_-_36338514 1.10 ENSDART00000157826
mpp1
membrane protein, palmitoylated 1
chr2_+_43736542 1.09 ENSDART00000148454
itgb1b.1
integrin, beta 1b.1
chr8_+_29733109 1.07 ENSDART00000020621
mapk4
mitogen-activated protein kinase 4
chr15_-_12484651 1.06 ENSDART00000162258
BX901957.1
ENSDARG00000098363
chr22_+_223797 1.05

chr15_+_28435937 1.05 ENSDART00000142298
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr19_+_48499602 1.04

chr8_+_28513670 1.04 ENSDART00000110291
srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
chr2_+_1602501 1.03 ENSDART00000109668
bcl10
B-cell CLL/lymphoma 10
chr12_+_16235258 1.00 ENSDART00000141169
ppp1r3cb
protein phosphatase 1, regulatory subunit 3Cb
chr21_-_4842528 0.99 ENSDART00000097796
rnf165a
ring finger protein 165a
chr2_+_4366169 0.98 ENSDART00000157903
gata6
GATA binding protein 6
chr12_-_36138709 0.98 ENSDART00000130985
st6galnac
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase
chr24_+_17125429 0.97 ENSDART00000017605
spag6
sperm associated antigen 6
chr2_+_16492315 0.96 ENSDART00000135783
selj
selenoprotein J
KN150475v1_-_1760 0.96

chr11_-_11317608 0.96 ENSDART00000113311
col9a1a
collagen, type IX, alpha 1a
chr11_-_25803101 0.95 ENSDART00000088888
kaznb
kazrin, periplakin interacting protein b
chr11_-_25693072 0.93 ENSDART00000122011
kaznb
kazrin, periplakin interacting protein b
chr7_-_6296880 0.93 ENSDART00000172954
si:ch1073-153i20.4
si:ch1073-153i20.4
chr23_+_22729939 0.93 ENSDART00000009337
eno1a
enolase 1a, (alpha)
chr16_-_33637966 0.93 ENSDART00000142965
BX511161.1
ENSDARG00000092272
chr24_-_26254551 0.93 ENSDART00000112317
zgc:194621
zgc:194621
chr10_+_16634200 0.92 ENSDART00000101142
chsy3
chondroitin sulfate synthase 3
chr12_-_650506 0.91 ENSDART00000172651
sult2st2
sulfotransferase family 2, cytosolic sulfotransferase 2
chr8_-_27667972 0.91 ENSDART00000086946
mov10b.1
Moloney leukemia virus 10b, tandem duplicate 1
chr6_+_59749159 0.90

chr12_-_3270927 0.90 ENSDART00000175918
CABZ01063170.1
ENSDARG00000107441
chr1_+_21309690 0.90 ENSDART00000141317
dnah6
dynein, axonemal, heavy chain 6
chr18_-_54695 0.89

chr5_-_60967429 0.88 ENSDART00000050914
si:dkey-261j4.4
si:dkey-261j4.4
chr6_+_6640324 0.88 ENSDART00000150967
si:ch211-85n16.3
si:ch211-85n16.3
chr10_-_36864268 0.88 ENSDART00000165853
dhrs13a.1
dehydrogenase/reductase (SDR family) member 13a, tandem duplicate 1
chr5_+_71611136 0.87 ENSDART00000163906
CABZ01115396.1
ENSDARG00000099805
chr8_+_999710 0.87 ENSDART00000081432
sprb
sepiapterin reductase b
chr11_+_666006 0.86 ENSDART00000130839
timp4.1
TIMP metallopeptidase inhibitor 4, tandem duplicate 1
chr20_+_34417665 0.85 ENSDART00000153207
ivns1abpa
influenza virus NS1A binding protein a
chr2_-_44402486 0.85 ENSDART00000011188
ENSDART00000093298
atp1a2a
ATPase, Na+/K+ transporting, alpha 2a polypeptide
chr16_+_7709183 0.85 ENSDART00000065514
stx12l
syntaxin 12, like
KN150487v1_+_38777 0.84

chr23_-_9990121 0.84 ENSDART00000127029
si:ch211-220i18.4
si:ch211-220i18.4
chr24_+_252774 0.82 ENSDART00000178656
ENSDART00000175867
CABZ01080224.1
ENSDARG00000107432
chr10_-_8336541 0.82 ENSDART00000163803
plpp1a
phospholipid phosphatase 1a
chr24_-_32750010 0.82 ENSDART00000038364
ca2
carbonic anhydrase II
chr25_-_31291943 0.81 ENSDART00000175104
lamb4
laminin, beta 4
chr7_-_72127164 0.81 ENSDART00000176069
CABZ01057364.1
ENSDARG00000106736
chr18_-_26483645 0.80

chr5_+_65267043 0.79 ENSDART00000161578
mymk
myomaker, myoblast fusion factor
chr19_-_2939818 0.78

KN150680v1_+_10854 0.77

chr4_+_5240888 0.77 ENSDART00000150391
si:ch211-214j24.14
si:ch211-214j24.14
chr5_-_67083987 0.77 ENSDART00000167301
b4galt4
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
chr6_+_53349584 0.77 ENSDART00000167079
si:ch211-161c3.5
si:ch211-161c3.5
chr5_+_51201924 0.76 ENSDART00000087467
cmya5
cardiomyopathy associated 5
chr4_-_16365281 0.76 ENSDART00000139919
lum
lumican
chr2_+_21267793 0.75 ENSDART00000099913
pla2g4aa
phospholipase A2, group IVAa (cytosolic, calcium-dependent)
chr15_+_2590598 0.75 ENSDART00000178505
SH2B2
SH2B adaptor protein 2
chr12_+_22605268 0.74

chr9_-_23936295 0.74 ENSDART00000165907
ndufa10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10
chr4_+_45204456 0.74 ENSDART00000158744
BX927336.3
ENSDARG00000102848
KN149874v1_+_3898 0.74

chr22_+_5657904 0.74 ENSDART00000138102
dnase1l4.2
deoxyribonuclease 1 like 4, tandem duplicate 2
chr14_-_46648119 0.74

chr21_+_45325383 0.73 ENSDART00000029946
ube2b
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr18_+_6664159 0.72

chr23_+_29981525 0.72 ENSDART00000035755
dvl1a
dishevelled segment polarity protein 1a
chr24_+_2740747 0.72 ENSDART00000169394
LYRM4
LYR motif containing 4
chr23_-_17543731 0.72 ENSDART00000002398
trim101
tripartite motif containing 101
chr13_+_51769487 0.71 ENSDART00000169928
ENSDART00000160698
klhdc3
kelch domain containing 3
chr1_+_44414936 0.71

chr20_+_6165025 0.70 ENSDART00000077072
CABZ01062780.1
ENSDARG00000037190
chr14_-_1081316 0.70

chr25_+_30472954 0.70

chr25_-_35037680 0.69 ENSDART00000097651
si:ch211-87j1.4
si:ch211-87j1.4
chr1_+_157674 0.69 ENSDART00000152205
ENSDART00000160843
cul4a
cullin 4A
chr3_+_1440282 0.69 ENSDART00000158633
poldip3
polymerase (DNA-directed), delta interacting protein 3
chr16_+_5411816 0.68

chr22_+_20695983 0.68 ENSDART00000171321
si:dkey-211f22.5
si:dkey-211f22.5
chr20_+_23392782 0.67

chr8_+_52633069 0.67 ENSDART00000162953
cyr61l2
cysteine-rich, angiogenic inducer, 61 like 2
chr18_+_91971 0.67

chr3_+_17387551 0.66 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr8_-_20357907 0.65

chr20_-_53629996 0.65 ENSDART00000141826
mettl24
methyltransferase like 24
chr19_-_44043682 0.65 ENSDART00000138009
ENSDART00000086138
fam83hb
family with sequence similarity 83, member Hb
chr8_-_11806627 0.64 ENSDART00000064017
rapgef1a
Rap guanine nucleotide exchange factor (GEF) 1a
chr11_+_30048913 0.64

chr10_-_24690263 0.64 ENSDART00000163102
proser1
proline and serine rich 1
chr23_-_3815492 0.64 ENSDART00000131536
hmga1a
high mobility group AT-hook 1a
chr22_-_38271070 0.64 ENSDART00000165430
ENSDART00000059690
hps3
Hermansky-Pudlak syndrome 3
chr24_-_36449162 0.63 ENSDART00000154402
si:ch211-40k21.9
si:ch211-40k21.9
chr10_-_28638101 0.63 ENSDART00000177781
bbx
bobby sox homolog (Drosophila)
chr21_-_45341242 0.62 ENSDART00000075438
cdkn2aipnl
CDKN2A interacting protein N-terminal like
chr23_+_22408855 0.62 ENSDART00000147696
rap1gap
RAP1 GTPase activating protein
chr16_+_42868905 0.62 ENSDART00000156601
si:ch211-135n15.2
si:ch211-135n15.2
chr17_+_29316965 0.62

chr1_-_54331157 0.62 ENSDART00000083572
zgc:136864
zgc:136864
chr14_+_28126739 0.62 ENSDART00000026846
pin4
protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)
chr11_-_41512092 0.61 ENSDART00000173147
FP325130.3
ENSDARG00000105426
chr3_-_62143464 0.61 ENSDART00000155853
gprc5ba
G protein-coupled receptor, class C, group 5, member Ba
chr7_+_69232260 0.61 ENSDART00000073861
gabarapb
GABA(A) receptor-associated protein b
chr11_-_11487856 0.60 ENSDART00000030103
krt94
keratin 94
chr25_-_727490 0.60

chr9_+_33177527 0.60 ENSDART00000174533
vangl1
VANGL planar cell polarity protein 1
chr2_+_289138 0.60 ENSDART00000157246
znf1008
zinc finger protein 1008
chr7_-_30451749 0.59 ENSDART00000052539
myo1ea
myosin IE, a
chr24_-_2740524 0.59 ENSDART00000171805
fars2
phenylalanyl-tRNA synthetase 2, mitochondrial
chr18_+_54352 0.59 ENSDART00000097163
SLC27A2 (1 of many)
solute carrier family 27 member 2
chr14_-_46648350 0.58

chr12_+_29648614 0.58 ENSDART00000161533
gfra1b
gdnf family receptor alpha 1b
chr1_-_10423289 0.58

chr7_+_1397973 0.58

chr15_-_47269988 0.57 ENSDART00000151594
h3f3b.1
H3 histone, family 3B.1
chr20_+_9776103 0.57 ENSDART00000053834
psmc6
proteasome 26S subunit, ATPase 6
chr20_-_296201 0.57 ENSDART00000104806
wisp3
WNT1 inducible signaling pathway protein 3
chr2_-_44402452 0.56 ENSDART00000011188
ENSDART00000093298
atp1a2a
ATPase, Na+/K+ transporting, alpha 2a polypeptide
chr17_+_135261 0.56 ENSDART00000166339
klhdc2
kelch domain containing 2
KN149895v1_+_73008 0.56

chr1_-_518543 0.55 ENSDART00000138032
trmt10c
tRNA methyltransferase 10C, mitochondrial RNase P subunit
chr7_+_48726955 0.55 ENSDART00000166329
si:ch211-288d18.1
si:ch211-288d18.1
chr3_-_1421391 0.54 ENSDART00000149709
smdt1a
single-pass membrane protein with aspartate-rich tail 1a
chr16_+_330953 0.54 ENSDART00000102977
nrsn1
neurensin 1
chr14_-_29565869 0.54 ENSDART00000172349
sorbs2b
sorbin and SH3 domain containing 2b
chr2_-_42510909 0.54 ENSDART00000144274
si:dkey-7l6.3
si:dkey-7l6.3
chr2_-_45386850 0.53

chr23_-_5080531 0.52

chr3_+_39617522 0.52

chr20_+_25326042 0.52 ENSDART00000130494
moxd1
monooxygenase, DBH-like 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.5 1.6 GO:0070254 mucus secretion(GO:0070254)
0.5 2.1 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880) release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0014808) sarcoplasmic reticulum calcium ion transport(GO:0070296) calcium ion transport from endoplasmic reticulum to cytosol(GO:1903514)
0.5 1.4 GO:0010084 specification of organ axis polarity(GO:0010084)
0.4 2.2 GO:0090527 actin filament reorganization(GO:0090527)
0.4 1.3 GO:0007585 respiratory gaseous exchange(GO:0007585) regulation of respiratory gaseous exchange(GO:0043576)
0.4 1.7 GO:0032374 regulation of sterol transport(GO:0032371) regulation of cholesterol transport(GO:0032374)
0.4 1.6 GO:0006747 FAD biosynthetic process(GO:0006747) FAD metabolic process(GO:0046443) flavin adenine dinucleotide metabolic process(GO:0072387) flavin adenine dinucleotide biosynthetic process(GO:0072388)
0.4 2.7 GO:0048769 sarcomerogenesis(GO:0048769)
0.4 1.4 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.3 0.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.3 0.8 GO:0015670 carbon dioxide transport(GO:0015670)
0.3 1.6 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 0.9 GO:0032889 regulation of vacuole fusion, non-autophagic(GO:0032889)
0.2 0.7 GO:0001659 temperature homeostasis(GO:0001659) sleep(GO:0030431)
0.2 1.3 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.2 0.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 1.8 GO:0033292 T-tubule organization(GO:0033292)
0.2 0.8 GO:0042698 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698) inflammatory response to wounding(GO:0090594)
0.2 2.8 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.2 0.5 GO:0042423 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.2 0.5 GO:0021610 glossopharyngeal nerve development(GO:0021563) facial nerve morphogenesis(GO:0021610)
0.2 1.2 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.2 0.9 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 2.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.4 GO:0097250 mitochondrial respiratory chain supercomplex assembly(GO:0097250)
0.1 1.0 GO:0001773 myeloid dendritic cell activation(GO:0001773) myeloid dendritic cell differentiation(GO:0043011) dendritic cell differentiation(GO:0097028)
0.1 2.7 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.7 GO:0090178 establishment of planar polarity of embryonic epithelium(GO:0042249) establishment of planar polarity involved in neural tube closure(GO:0090177) regulation of establishment of planar polarity involved in neural tube closure(GO:0090178) planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.1 1.9 GO:0051764 actin crosslink formation(GO:0051764)
0.1 0.9 GO:0042574 retinal metabolic process(GO:0042574)
0.1 2.9 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.6 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.1 0.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.8 GO:0014743 regulation of muscle hypertrophy(GO:0014743) muscle hypertrophy(GO:0014896)
0.1 0.9 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 0.3 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.1 0.5 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.1 2.1 GO:0007568 aging(GO:0007568)
0.1 2.2 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919)
0.1 0.6 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.9 GO:0051923 sulfation(GO:0051923)
0.1 1.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 1.3 GO:0015807 L-amino acid transport(GO:0015807)
0.1 0.8 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.3 GO:0045598 regulation of fat cell differentiation(GO:0045598)
0.1 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.1 1.4 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.1 1.4 GO:0071218 response to misfolded protein(GO:0051788) cellular response to misfolded protein(GO:0071218)
0.1 1.1 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 1.1 GO:0033627 cell adhesion mediated by integrin(GO:0033627)
0.1 0.2 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.1 1.0 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962) regulation of polysaccharide biosynthetic process(GO:0032885)
0.1 1.1 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.7 GO:0000737 DNA catabolic process, endonucleolytic(GO:0000737)
0.1 0.7 GO:2000134 negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.9 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 1.0 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.4 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.3 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 0.4 GO:0032264 IMP salvage(GO:0032264)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0030183 B cell differentiation(GO:0030183)
0.0 0.2 GO:2000009 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.8 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.5 GO:0006265 DNA topological change(GO:0006265)
0.0 1.0 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 0.2 GO:0045050 protein insertion into ER membrane by stop-transfer membrane-anchor sequence(GO:0045050) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.0 1.0 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.0 1.3 GO:0048278 vesicle docking(GO:0048278)
0.0 2.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.7 GO:0016574 histone ubiquitination(GO:0016574)
0.0 0.8 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.5 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.8 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 1.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0061702 inflammasome complex(GO:0061702)
0.5 1.6 GO:0098594 mucin granule(GO:0098594)
0.3 2.8 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.3 1.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 2.7 GO:0031430 M band(GO:0031430)
0.2 2.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 0.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 1.8 GO:0016011 dystroglycan complex(GO:0016011)
0.2 0.6 GO:0070062 extracellular exosome(GO:0070062)
0.1 2.1 GO:0030315 T-tubule(GO:0030315)
0.1 0.9 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 2.7 GO:0005861 troponin complex(GO:0005861)
0.1 1.0 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.1 0.7 GO:0033503 HULC complex(GO:0033503)
0.1 0.5 GO:0032420 stereocilium(GO:0032420)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 1.1 GO:0043195 terminal bouton(GO:0043195)
0.1 0.8 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.1 0.6 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 1.4 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)
0.1 0.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.6 GO:0042645 nucleoid(GO:0009295) ribonuclease P complex(GO:0030677) mitochondrial nucleoid(GO:0042645)
0.1 1.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.5 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.9 GO:0030286 dynein complex(GO:0030286)
0.0 2.8 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 0.8 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.0 2.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.5 GO:0000786 nucleosome(GO:0000786)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.6 GO:0005902 microvillus(GO:0005902)
0.0 0.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.6 GO:0000785 chromatin(GO:0000785)
0.0 0.2 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0005882 intermediate filament(GO:0005882)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0004985 opioid receptor activity(GO:0004985)
0.7 2.2 GO:0032090 Pyrin domain binding(GO:0032090)
0.4 1.6 GO:0003919 FMN adenylyltransferase activity(GO:0003919)
0.4 1.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.4 1.1 GO:0098634 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.3 1.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.3 1.7 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 2.2 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.3 0.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 0.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 1.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 1.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 0.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 0.9 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.2 0.9 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 0.5 GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) carboxyl- or carbamoyltransferase activity(GO:0016743)
0.2 2.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 6.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 2.8 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 1.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.1 1.8 GO:0043236 laminin binding(GO:0043236)
0.1 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 1.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.5 GO:0033149 FFAT motif binding(GO:0033149)
0.1 1.4 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 2.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 1.0 GO:2001069 glycogen binding(GO:2001069)
0.1 1.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 1.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.6 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 0.3 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 1.7 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.8 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 1.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.8 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.0 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 1.0 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 2.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 1.4 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.4 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 2.9 GO:0061659 ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 1.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.8 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 1.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.8 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 0.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 0.7 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 2.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.0 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.4 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 1.6 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.7 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport