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Results for tbp

Z-value: 2.45

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Transcription factors associated with tbp

Gene Symbol Gene ID Gene Info
ENSDARG00000014994 TATA box binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tbpdr10_dc_chr13_-_24265471_24265568-0.621.0e-02Click!

Activity profile of tbp motif

Sorted Z-values of tbp motif

Network of associatons between targets according to the STRING database.

First level regulatory network of tbp

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_-_45950530 10.39 ENSDART00000060822
antifreeze protein type IV
chr2_+_17112049 10.11 ENSDART00000125647
transferrin-a
chr5_+_37378340 9.16 ENSDART00000012050
apolipoprotein A-Ia
chr3_-_32686790 8.90 ENSDART00000075465
myosin light chain, phosphorylatable, fast skeletal muscle a
chr5_-_31674204 8.41 ENSDART00000122889
myosin, heavy polypeptide 1.3, skeletal muscle
chr12_-_17590507 8.35 ENSDART00000010144
parvalbumin 2
chr8_-_16577737 7.55 ENSDART00000139038
ENSDARG00000092337
chr8_+_933677 6.97 ENSDART00000149528
fatty acid binding protein 1b, tandem duplicate 1
chr16_+_24045774 6.15 ENSDART00000133484
apolipoprotein Eb
chr5_+_4033390 6.10 ENSDART00000149185
spermidine/spermine N1-acetyltransferase 1a, duplicate 2
chr5_-_24982964 5.90 ENSDART00000031665
ENSDART00000161043
annexin A1a
chr2_-_7693224 5.75 ENSDART00000167019
wu:fc46h12
chr11_+_7139675 5.72 ENSDART00000155864
ENSDARG00000097452
chr9_-_22434581 5.62 ENSDART00000114943
crystallin, gamma M2d4
KN150173v1_-_16439 5.58 ENSDART00000162810
Small nucleolar RNA SNORD60
chr23_-_10242377 5.50 ENSDART00000129044
keratin 5
chr5_+_68410884 5.42 ENSDART00000153691
ENSDARG00000097815
chr14_-_46651359 5.41 ENSDART00000163316
ENSDARG00000099970
chr5_-_70948223 5.40 ENSDART00000013404
adenylate kinase 1
chr8_+_26799298 5.31 ENSDART00000134987
si:ch211-156j16.1
chr9_-_45802484 5.26 ENSDART00000139019
anterior gradient 1
chr5_-_36237656 5.17 ENSDART00000032481
creatine kinase, muscle a
chr18_-_45750 5.12 ENSDART00000148821
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr24_-_41448993 5.07 ENSDART00000041349
crystallin, gamma N2
chr11_+_6446302 4.96 ENSDART00000140707
ENSDART00000036939
growth arrest and DNA-damage-inducible, beta a
chr9_-_22402341 4.88 ENSDART00000110656
crystallin, gamma M2d20
chr4_+_828545 4.86 ENSDART00000067461
si:ch211-152c2.3
chr9_-_22470612 4.79 ENSDART00000123763
crystallin, gamma M2d3
chr4_-_26333625 4.72 ENSDART00000170709
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
KN149795v1_-_24393 4.67

chr2_+_24852094 4.65 ENSDART00000052063
ribosomal protein S28
chr6_+_251026 4.63 ENSDART00000042970
activating transcription factor 4a
chr19_-_5429428 4.62 ENSDART00000066620
ENSDART00000151398
keratin type 1 c19e
chr6_-_54172509 4.61 ENSDART00000149468
ribosomal protein S10
chr25_+_34515221 4.56 ENSDART00000046218
filamin C, gamma a (actin binding protein 280)
chr10_-_6816534 4.56 ENSDART00000110735
zgc:194281
chr9_-_22371512 4.16 ENSDART00000101809
crystallin, gamma M2d6
chr23_-_21520413 4.14 ENSDART00000044080
ENSDART00000112929
hairy-related 12
chr9_-_22507592 4.09 ENSDART00000132029
crystallin, gamma M2d2
chr8_+_6819898 4.07 ENSDART00000101450
ENSDART00000064163
neurofilament, medium polypeptide b
chr3_+_15355472 4.06 ENSDART00000141714
nuclear protein 1
chr13_-_12513113 4.03

chr9_-_22318918 3.99 ENSDART00000124272
crystallin, gamma M2d17
chr24_-_1307905 3.98 ENSDART00000159212
neuropilin 1a
chr23_+_19887319 3.96 ENSDART00000139192
emerin (Emery-Dreifuss muscular dystrophy)
chr19_+_17832515 3.93 ENSDART00000149045
Kruppel-like factor 2b
chr24_+_32261533 3.91 ENSDART00000003745
vimentin
chr9_-_52847086 3.81 ENSDART00000171721
death associated protein 1b
chr9_-_22488422 3.76 ENSDART00000124600
crystallin, gamma M2d21
chr2_+_24881103 3.76 ENSDART00000144149
angiopoietin-like 4
chr17_-_52020689 3.74 ENSDART00000019766
transforming growth factor, beta 3
chr10_-_44180588 3.64 ENSDART00000145404
crystallin, beta B1
chr15_+_28435937 3.63 ENSDART00000142298
solute carrier family 43 (amino acid system L transporter), member 2a
chr22_+_26543146 3.63

KN150074v1_-_1031 3.63

chr11_-_11591394 3.58 ENSDART00000142208
zgc:110712
chr23_+_27749014 3.57 ENSDART00000128833
ribosomal protein S26
chr9_-_22324699 3.57 ENSDART00000175417
ENSDART00000101902
crystallin, gamma M2d8
chr20_-_54192057 3.56 ENSDART00000023550
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2
chr23_+_25378921 3.55 ENSDART00000143291
ribosomal protein L41
chr5_-_21523520 3.54 ENSDART00000023306
ankyrin repeat and SOCS box-containing 12a
chr15_-_5827067 3.54 ENSDART00000102459
retinol binding protein 2a, cellular
chr14_+_46419051 3.51 ENSDART00000112377
microtubule-associated protein 1 light chain 3 gamma, like
chr20_-_9992898 3.46 ENSDART00000080664
zgc:86709
chr9_-_22306541 3.46 ENSDART00000101916
crystallin, gamma M2d15
chr21_-_28486800 3.46 ENSDART00000077910
ependymin-like 2
chr22_+_16471319 3.42 ENSDART00000014330
immediate early response 5
chr2_-_38017902 3.37 ENSDART00000034790
Purkinje cell protein 4 like 1
chr6_+_35378839 3.37 ENSDART00000102483
ENSDART00000133783
regulator of G protein signaling 4
chr9_-_1701626 3.36 ENSDART00000163482
heterogeneous nuclear ribonucleoprotein A3
chr22_-_10372023 3.34

chr19_-_16126342 3.29

chr6_-_43094573 3.18 ENSDART00000084389
leucine rich repeat neuronal 1
chr9_-_22461196 3.05 ENSDART00000135190
crystallin, gamma M2d7
chr8_-_31359923 3.01 ENSDART00000019937
growth arrest and DNA-damage-inducible, gamma a
chr15_+_548292 2.95 ENSDART00000178563
finTRIM family, member 86
chr3_-_31672763 2.95 ENSDART00000028270
glial fibrillary acidic protein
chr1_+_54460288 2.90 ENSDART00000138070
ENSDART00000150510
myoglobin
chr25_-_13580057 2.86 ENSDART00000090226
zinc finger protein 319b
chr18_-_45892 2.81 ENSDART00000052641
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr9_-_22347397 2.79 ENSDART00000146188
crystallin, gamma M2d16
chr24_+_21476448 2.79 ENSDART00000002595
ribosomal protein L21
chr8_+_48624273 2.78 ENSDART00000121432
natriuretic peptide A
chr1_+_9999842 2.76 ENSDART00000152438
ENSDARG00000037679
chr18_+_26102262 2.76 ENSDART00000164495
zinc finger protein 710a
chr8_+_46651079 2.72 ENSDART00000113803
hairy-related 3
chr11_-_6960107 2.71 ENSDART00000171255
cartilage oligomeric matrix protein
chr20_+_27506658 2.70

chr25_+_8279754 2.64 ENSDART00000073410
mucin 5.1, oligomeric mucus/gel-forming
chr12_-_22438379 2.63 ENSDART00000177715
ENSDARG00000108493
chr20_-_475417 2.59 ENSDART00000032212
fyn-related Src family tyrosine kinase
chr24_-_33617592 2.56

chr10_-_37131530 2.52 ENSDART00000132023
myosin XVIIIAa
chr21_-_39013447 2.51 ENSDART00000114885
aldehyde dehydrogenase 3 family, member A2b
chr22_+_520496 2.50 ENSDART00000067638
mediator complex subunit 20
chr1_+_9999665 2.50 ENSDART00000054879
ENSDARG00000037679
chr7_+_20272091 2.49 ENSDART00000052917
solute carrier family 3 (amino acid transporter heavy chain), member 2a
chr2_-_30198789 2.40 ENSDART00000019149
ribosomal protein L7
chr22_+_5722410 2.39 ENSDART00000143052
COX14 cytochrome c oxidase assembly factor
chr20_-_4695108 2.35 ENSDART00000167224
ENSDART00000125620
ENSDART00000053858
poly(A) polymerase alpha
chr3_-_55995924 2.34 ENSDART00000167356
transcription factor AP-4 (activating enhancer binding protein 4)
chr12_-_36294319 2.33 ENSDART00000157746
ENSDART00000166925
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr16_-_2322075 2.32

chr9_+_24089828 2.32 ENSDART00000127859
tripartite motif containing 63b
chr10_-_24401876 2.26 ENSDART00000149362
phosphatidylinositol transfer protein, alpha b
chr7_-_31170266 2.23 ENSDART00000075398
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr9_-_32942783 2.23 ENSDART00000060006
oligodendrocyte lineage transcription factor 2
chr14_-_27703812 2.22 ENSDART00000054115
TSC22 domain family, member 3
chr5_-_67233396 2.21 ENSDART00000051833
ENSDART00000124890
GS homeobox 1
chr19_-_5416317 2.19 ENSDART00000010373
keratin, type 1, gene 19d
chr13_-_1177857 2.19 ENSDART00000111052
oligodendrocyte transcription factor 3
chr2_+_1602501 2.17 ENSDART00000109668
B-cell CLL/lymphoma 10
chr25_+_30535271 2.16

chr21_-_20305406 2.16 ENSDART00000065659
retinol binding protein 4, like
chr2_+_4233224 2.14 ENSDART00000163737
mindbomb E3 ubiquitin protein ligase 1
chr5_-_63487161 2.07 ENSDART00000048395
cardiac myosin light chain-1
chr14_-_45883839 2.06

chr10_+_44364117 2.05

chr19_+_42183946 2.04 ENSDART00000087096
tubulointerstitial nephritis antigen-like 1
chr11_+_15478585 2.03 ENSDART00000163289
ENSDART00000066033
growth differentiation factor 11
chr15_+_895792 2.01

chr11_+_33972923 2.00 ENSDART00000172594
family with sequence similarity 43, member A
chr23_+_27052594 1.98 ENSDART00000109712
ENSDART00000018654
Rho family GTPase 1b
chr4_-_20764499 1.97 ENSDART00000023337
N-acyl phosphatidylethanolamine phospholipase D
chr22_-_11596329 1.94 ENSDART00000063133
glucagon a
chr5_-_40451061 1.94 ENSDART00000083515
PDZ domain containing 2
chr7_+_73601671 1.94 ENSDART00000163075
zgc:173552
chr22_+_10372455 1.92 ENSDART00000122403
wu:fb55g09
chr14_-_32993686 1.92 ENSDART00000146999
ribosomal protein L39
chr24_-_25546068 1.91 ENSDART00000015391
cholinergic receptor, nicotinic, delta (muscle)
chr3_+_5665300 1.91 ENSDART00000101807
si:ch211-106h11.3
chr24_-_4117031 1.83 ENSDART00000147849
Kruppel-like factor 6a
chr7_+_71658461 1.83

chr4_-_71335661 1.81

chr8_+_17042976 1.78 ENSDART00000023206
polo-like kinase 2b (Drosophila)
chr25_+_34627031 1.76 ENSDART00000154377
histone cluster 1 H2B family member a
chr19_-_44459390 1.76 ENSDART00000125168
ubiquinol-cytochrome c reductase binding protein
chr13_+_1398289 1.76

chr12_-_19224698 1.74 ENSDART00000044860
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr1_-_21987718 1.73 ENSDART00000128918
fibroblast growth factor binding protein 1b
chr3_-_36465046 1.71 ENSDART00000172003
si:dkeyp-72e1.6
chr9_-_30453625 1.67 ENSDART00000060150
MID1 interacting protein 1a
chr23_-_10242235 1.67 ENSDART00000081223
ENSDART00000144280
keratin 5
chr3_+_33209227 1.66 ENSDART00000128786
peptide YYa
chr5_+_8843643 1.62 ENSDART00000149417
ENSDART00000061616
T-cell acute lymphocytic leukemia 2
chr23_+_18176720 1.59 ENSDART00000010270
major facilitator superfamily domain containing 4Ab
chr11_-_38940966 1.56 ENSDART00000105133
wingless-type MMTV integration site family, member 4a
chr11_-_42826276 1.55

chr1_-_33981055 1.54 ENSDART00000102111
tumor protein, translationally-controlled 1
chr20_-_54192092 1.54 ENSDART00000023550
heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 2
chr10_-_7827244 1.52 ENSDART00000111058
myeloid-specific peroxidase
chr13_+_30546398 1.51

chr5_-_13184573 1.49 ENSDART00000018351
zgc:65851
chr2_-_59006559 1.48

chr24_-_1308047 1.47 ENSDART00000164904
neuropilin 1a
chr21_+_10663517 1.46 ENSDART00000074833
retinal homeobox gene 3
chr3_+_15355424 1.45 ENSDART00000141714
nuclear protein 1
chr7_-_35042805 1.43 ENSDART00000005053
solute carrier family 12 (potassium/chloride transporter), member 4
chr22_+_38028979 1.43 ENSDART00000165078
ENSDART00000159906
ENSDARG00000100625
chr18_-_16934961 1.41 ENSDART00000122102
WEE1 G2 checkpoint kinase
chr21_-_37924790 1.41 ENSDART00000131490
ripply transcriptional repressor 1
chr22_-_14247636 1.41

chr24_+_37800773 1.40 ENSDART00000137017
H3 histone, family 3D
chr21_-_14276856 1.39

chr3_+_19849761 1.39

chr8_+_7237516 1.39

chr7_-_13638486 1.35 ENSDART00000169828
retinaldehyde binding protein 1a
chr10_-_22875997 1.35 ENSDART00000079454
vesicle-associated membrane protein 2
chr17_-_37266525 1.34 ENSDART00000128715
kinesin family member 3Cb
chr13_+_24417183 1.34 ENSDART00000177677
lectin, galactoside-binding-like b
chr21_+_32285006 1.33

chr3_-_14348442 1.32 ENSDART00000172102
ELF1 homolog, elongation factor 1
chr16_+_24045707 1.31 ENSDART00000058965
apolipoprotein Eb
chr25_-_352985 1.31 ENSDART00000165705
sizzled
chr8_-_6833841 1.31 ENSDART00000005321
neurofilament, light polypeptide b
chr19_+_20392669 1.30 ENSDART00000052627
neuropeptide VF precursor
chr21_+_43674754 1.29 ENSDART00000136025
trimethyllysine hydroxylase, epsilon
chr24_-_25545773 1.29 ENSDART00000015391
cholinergic receptor, nicotinic, delta (muscle)
chr10_-_35015129 1.28 ENSDART00000156045
ENSDARG00000098015
chr13_-_2083873 1.28 ENSDART00000129773
muscular LMNA-interacting protein
chr1_+_28293053 1.24 ENSDART00000075539
crystallin, alpha A
chr2_-_7560202 1.24 ENSDART00000164494
agouti signaling protein, nonagouti homolog (mouse) 2b
chr7_+_73594790 1.23 ENSDART00000123081
zgc:173552
chr24_-_32281758 1.21 ENSDART00000151845
tRNA aspartic acid methyltransferase 1
chr22_-_26307952 1.20

chr22_-_10135735 1.20 ENSDART00000142012
RanBP-type and C3HC4-type zinc finger containing 1
chr2_+_24851910 1.19 ENSDART00000133109
ribosomal protein S28
chr14_+_10350918 1.18 ENSDART00000125865
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr11_-_5617162 1.18 ENSDART00000066168
peroxisomal biogenesis factor 11 gamma
chr20_-_7141247 1.17 ENSDART00000160910
si:ch211-121a2.4
chr4_+_73490746 1.17 ENSDART00000174082
nucleoporin 50
chr2_+_43719715 1.17 ENSDART00000037808
integrin, beta 1b.2
chr3_-_59179368 1.14 ENSDART00000100327
neuronal pentraxin 1 like
chr14_-_10311677 1.13 ENSDART00000133723
si:dkey-92i17.2
chr6_-_34955205 1.12 ENSDART00000131610
SERPINE1 mRNA binding protein 1a
chr5_-_64396143 1.10 ENSDART00000168486
inositol polyphosphate-5-phosphatase E
chr13_-_40027211 1.07

chr22_-_17570275 1.07 ENSDART00000099056
glutathione peroxidase 4a
chr24_-_24017962 1.05 ENSDART00000080602
MAP7 domain containing 2b
chr20_+_27121126 1.04 ENSDART00000126919
ENSDART00000016014
chromogranin A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 10.1 GO:0019730 antimicrobial humoral response(GO:0019730) antibacterial humoral response(GO:0019731)
3.3 16.7 GO:0065005 plasma lipoprotein particle assembly(GO:0034377) high-density lipoprotein particle assembly(GO:0034380) protein-lipid complex assembly(GO:0065005)
2.6 7.9 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
2.0 5.9 GO:0002824 positive regulation of adaptive immune response(GO:0002821) positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains(GO:0002824) negative regulation of phospholipase activity(GO:0010519) positive regulation of vesicle fusion(GO:0031340) type 2 immune response(GO:0042092) regulation of fatty acid biosynthetic process(GO:0042304) T-helper 2 cell differentiation(GO:0045064) leukocyte apoptotic process(GO:0071887) regulation of leukocyte apoptotic process(GO:2000106)
1.8 5.4 GO:0060055 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
1.7 5.0 GO:1904019 epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
1.5 6.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
1.3 3.9 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
1.0 5.1 GO:0046677 response to antibiotic(GO:0046677)
1.0 4.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
1.0 5.9 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
0.9 2.8 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.9 3.6 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.8 1.6 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.8 3.8 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.7 2.2 GO:0021742 abducens nucleus development(GO:0021742)
0.7 48.5 GO:0007601 visual perception(GO:0007601)
0.7 2.0 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.6 5.2 GO:0042396 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.5 2.1 GO:0061195 dorsal spinal cord development(GO:0021516) tongue development(GO:0043586) tongue morphogenesis(GO:0043587) taste bud development(GO:0061193) taste bud morphogenesis(GO:0061194) taste bud formation(GO:0061195) cranial ganglion development(GO:0061550)
0.5 4.6 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.5 10.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.5 1.5 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
0.5 3.2 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.4 1.7 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.4 3.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 2.1 GO:0055015 ventricular cardiac muscle cell differentiation(GO:0055012) ventricular cardiac muscle cell development(GO:0055015)
0.3 10.4 GO:0060030 dorsal convergence(GO:0060030)
0.3 4.6 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.3 1.0 GO:2000471 regulation of hematopoietic stem cell migration(GO:2000471)
0.3 2.5 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
0.3 1.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 0.9 GO:0003228 atrial cardiac muscle tissue development(GO:0003228)
0.3 2.9 GO:0015671 oxygen transport(GO:0015671)
0.3 1.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.2 2.4 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.2 4.5 GO:0015807 L-amino acid transport(GO:0015807)
0.2 0.9 GO:0045337 farnesyl diphosphate biosynthetic process(GO:0045337)
0.2 3.5 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.2 0.7 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.2 1.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 3.8 GO:0010507 negative regulation of autophagy(GO:0010507)
0.2 1.0 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 4.7 GO:0006491 N-glycan processing(GO:0006491)
0.2 0.5 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.2 1.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.2 0.3 GO:0048341 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
0.2 3.7 GO:0061035 regulation of cartilage development(GO:0061035)
0.1 1.7 GO:0042743 hydrogen peroxide metabolic process(GO:0042743)
0.1 7.1 GO:0007160 cell-matrix adhesion(GO:0007160)
0.1 12.4 GO:0031101 fin regeneration(GO:0031101)
0.1 1.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 1.7 GO:0007631 feeding behavior(GO:0007631)
0.1 1.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 0.7 GO:0030317 sperm motility(GO:0030317)
0.1 0.7 GO:0006046 N-acetylglucosamine catabolic process(GO:0006046)
0.1 1.4 GO:0006884 cell volume homeostasis(GO:0006884)
0.1 1.4 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 2.2 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.1 0.4 GO:2000008 regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 2.4 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 1.9 GO:0003323 type B pancreatic cell development(GO:0003323)
0.1 2.2 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 1.6 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.1 0.9 GO:0006465 signal peptide processing(GO:0006465)
0.1 0.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 1.4 GO:0007634 optokinetic behavior(GO:0007634)
0.1 2.3 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.8 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579) positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.1 2.4 GO:0031018 endocrine pancreas development(GO:0031018)
0.1 1.1 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 0.3 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.1 5.7 GO:0033993 response to lipid(GO:0033993)
0.1 2.5 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.1 1.3 GO:0048263 determination of dorsal identity(GO:0048263)
0.0 0.8 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.9 GO:0031124 mRNA 3'-end processing(GO:0031124)
0.0 3.2 GO:0042391 regulation of membrane potential(GO:0042391)
0.0 0.4 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.9 GO:0044773 mitotic DNA damage checkpoint(GO:0044773)
0.0 2.7 GO:0045665 negative regulation of neuron differentiation(GO:0045665)
0.0 1.3 GO:0021510 spinal cord development(GO:0021510)
0.0 0.6 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.3 GO:0042551 neuron maturation(GO:0042551)
0.0 1.8 GO:0001756 somitogenesis(GO:0001756)
0.0 0.2 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.0 2.0 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.0 GO:0046619 optic placode formation(GO:0001743) optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 1.2 GO:0006606 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 2.0 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.6 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.7 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 6.8 GO:0006412 translation(GO:0006412)
0.0 1.1 GO:0006979 response to oxidative stress(GO:0006979)
0.0 2.0 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.0 0.0 GO:0065001 specification of organ axis polarity(GO:0010084) specification of axis polarity(GO:0065001)
0.0 0.3 GO:0007007 inner mitochondrial membrane organization(GO:0007007)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 5.8 GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane(GO:0098556)
1.9 7.5 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.8 9.2 GO:0042627 chylomicron(GO:0042627)
1.5 4.6 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
1.1 5.4 GO:0005883 neurofilament(GO:0005883)
0.7 5.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.4 5.1 GO:0043209 myelin sheath(GO:0043209)
0.4 3.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 7.1 GO:0045095 keratin filament(GO:0045095)
0.3 15.3 GO:0005882 intermediate filament(GO:0005882)
0.2 11.7 GO:0016459 myosin complex(GO:0016459)
0.2 0.7 GO:0097225 sperm midpiece(GO:0097225)
0.2 0.9 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.2 1.3 GO:0042583 chromaffin granule(GO:0042583)
0.2 8.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 1.8 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 7.1 GO:0022626 cytosolic large ribosomal subunit(GO:0022625) cytosolic ribosome(GO:0022626)
0.1 1.2 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.9 GO:0005787 signal peptidase complex(GO:0005787)
0.1 3.4 GO:0000421 autophagosome membrane(GO:0000421)
0.1 8.9 GO:0055037 recycling endosome(GO:0055037)
0.1 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.1 2.1 GO:0030139 endocytic vesicle(GO:0030139)
0.0 2.5 GO:0016592 mediator complex(GO:0016592)
0.0 1.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 7.7 GO:0031012 extracellular matrix(GO:0031012)
0.0 1.2 GO:0008305 integrin complex(GO:0008305)
0.0 1.3 GO:0016605 PML body(GO:0016605)
0.0 3.0 GO:0000786 nucleosome(GO:0000786)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.5 GO:0005902 microvillus(GO:0005902)
0.0 1.0 GO:0031941 filamentous actin(GO:0031941)
0.0 0.6 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 6.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.4 GO:0098798 mitochondrial protein complex(GO:0098798)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.0 1.3 GO:0005871 kinesin complex(GO:0005871)
0.0 4.7 GO:0005764 lysosome(GO:0005764)
0.0 2.4 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 10.8 GO:0005576 extracellular region(GO:0005576)
0.0 1.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.0 GO:0005938 cell cortex(GO:0005938)
0.0 0.9 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
1.7 48.5 GO:0005212 structural constituent of eye lens(GO:0005212)
1.5 9.2 GO:0071814 lipoprotein particle binding(GO:0071813) protein-lipid complex binding(GO:0071814)
1.5 6.1 GO:0019809 polyamine binding(GO:0019808) spermidine binding(GO:0019809)
1.3 3.8 GO:0070513 death domain binding(GO:0070513)
0.8 7.0 GO:0005504 fatty acid binding(GO:0005504)
0.7 5.9 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.7 4.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.6 5.2 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.6 5.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.6 5.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.6 2.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.5 1.6 GO:0016743 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088) carboxyl- or carbamoyltransferase activity(GO:0016743)
0.5 3.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.5 2.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.4 2.2 GO:0034632 retinol transporter activity(GO:0034632)
0.4 4.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.4 1.3 GO:0005521 lamin binding(GO:0005521)
0.4 1.2 GO:0098634 C-X3-C chemokine binding(GO:0019960) protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.4 7.9 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.4 1.1 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.3 2.0 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3 3.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.3 2.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 2.9 GO:0005344 oxygen transporter activity(GO:0005344) oxygen binding(GO:0019825)
0.2 1.6 GO:0015145 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.2 2.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 4.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 1.4 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.1 0.9 GO:0016493 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950) C-C chemokine receptor activity(GO:0016493)
0.1 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.4 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 21.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 13.1 GO:0003774 motor activity(GO:0003774)
0.1 2.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 0.7 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.1 1.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.4 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 2.8 GO:0051427 hormone receptor binding(GO:0051427)
0.1 1.7 GO:0004601 peroxidase activity(GO:0004601)
0.1 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 1.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.2 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.0 0.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 4.7 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 1.0 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 25.0 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.7 GO:0019838 growth factor binding(GO:0019838)
0.0 3.8 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.0 0.7 GO:0008301 DNA binding, bending(GO:0008301)
0.0 9.5 GO:0005198 structural molecule activity(GO:0005198)
0.0 15.6 GO:0046983 protein dimerization activity(GO:0046983)
0.0 1.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 2.1 GO:0042802 identical protein binding(GO:0042802)
0.0 1.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.3 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.4 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 2.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.7 GO:0019213 deacetylase activity(GO:0019213)
0.0 1.9 GO:0001664 G-protein coupled receptor binding(GO:0001664)
0.0 1.2 GO:0043130 ubiquitin binding(GO:0043130)
0.0 1.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 2.0 GO:0019901 protein kinase binding(GO:0019901)
0.0 4.6 GO:0003779 actin binding(GO:0003779)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 3.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.2 2.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 7.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 3.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 7.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.0 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 1.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.5 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 ST FAS SIGNALING PATHWAY Fas Signaling Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.5 3.2 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.4 1.3 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.4 5.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.3 14.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.3 2.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 2.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 10.6 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 2.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 2.9 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 3.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 2.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 2.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.1 6.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 4.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 0.6 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 0.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 1.1 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.2 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 3.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 4.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism