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Results for tcf12

Z-value: 1.67

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Transcription factors associated with tcf12

Gene Symbol Gene ID Gene Info
tcf12
ENSDARG00000004714 transcription factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tcf12dr10_dc_chr7_-_52434786_524348230.862.0e-05Click!

Activity profile of tcf12 motif

Sorted Z-values of tcf12 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of tcf12

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr14_-_25659535 4.77 ENSDART00000135627
sparc
secreted protein, acidic, cysteine-rich (osteonectin)
chr2_-_16896965 4.32 ENSDART00000022549
atp1b3a
ATPase, Na+/K+ transporting, beta 3a polypeptide
chr19_-_30816780 4.18 ENSDART00000103475
agr2
anterior gradient 2
chr19_+_31046291 3.96 ENSDART00000052124
fam49al
family with sequence similarity 49, member A-like
chr10_+_15819127 3.91 ENSDART00000140511
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr4_-_14330113 3.84 ENSDART00000091151
nell2b
neural EGFL like 2b
chr7_+_49442972 3.80 ENSDART00000019446
ascl1b
achaete-scute family bHLH transcription factor 1b
chr18_-_11216447 3.69 ENSDART00000040500
tspan9a
tetraspanin 9a
chr7_+_6517248 3.50 ENSDART00000102681
pnp5a
purine nucleoside phosphorylase 5a
chr15_-_15421065 3.36 ENSDART00000106120
ywhag2
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr2_-_30675594 3.28 ENSDART00000087270
ctnnd2b
catenin (cadherin-associated protein), delta 2b
chr11_-_25803101 3.27 ENSDART00000088888
kaznb
kazrin, periplakin interacting protein b
chr18_+_62936 3.20 ENSDART00000052638
slc27a2a
solute carrier family 27 (fatty acid transporter), member 2a
chr10_+_33227967 3.20 ENSDART00000159666
myl10
myosin, light chain 10, regulatory
chr15_+_34131126 3.19 ENSDART00000169487
vwde
von Willebrand factor D and EGF domains
chr8_-_985673 3.12 ENSDART00000170737
smyd1b
SET and MYND domain containing 1b
chr24_-_33817169 3.08 ENSDART00000079292
cavin4b
caveolae associated protein 4b
chr18_-_3244618 3.03 ENSDART00000161520
gdpd4a
glycerophosphodiester phosphodiesterase domain containing 4a
chr9_-_23081918 3.02 ENSDART00000143888
neb
nebulin
chr7_+_40972616 3.02 ENSDART00000173814
scrib
scribbled planar cell polarity protein
chr7_+_39173765 2.92 ENSDART00000173748
tnnt3b
troponin T type 3b (skeletal, fast)
chr6_-_39315024 2.92 ENSDART00000012644
krt4
keratin 4
chr22_-_37468331 2.91 ENSDART00000160940
SOX2OT_exon1
SOX2 overlapping transcript exon 1
chr8_-_7049946 2.89 ENSDART00000045669
ENSDART00000162950
KRT73
keratin 73
chr10_-_43826919 2.88 ENSDART00000039551
ENSDART00000160786
ENSDART00000099134
mef2ca
myocyte enhancer factor 2ca
chr25_-_2485276 2.83 ENSDART00000154889
ENSDART00000155027
BX957346.1
ENSDARG00000096850
chr2_-_21693984 2.82 ENSDART00000171699
hhatla
hedgehog acyltransferase-like, a
chr23_+_21546553 2.81 ENSDART00000142921
si:ch73-21g5.7
si:ch73-21g5.7
chr23_+_24141576 2.75

chr5_-_40133824 2.71 ENSDART00000010896
isl1
ISL LIM homeobox 1
chr18_+_38307946 2.68 ENSDART00000134247
lmo2
LIM domain only 2 (rhombotin-like 1)
chr17_+_23278879 2.67 ENSDART00000153652
zgc:165461
zgc:165461
chr10_+_31358236 2.66 ENSDART00000145562
robo4
roundabout, axon guidance receptor, homolog 4 (Drosophila)
chr10_-_10372266 2.66

chr3_-_48865474 2.65 ENSDART00000133036
elavl3
ELAV like neuron-specific RNA binding protein 3
chr22_+_26543146 2.65

chr24_+_17125429 2.62 ENSDART00000017605
spag6
sperm associated antigen 6
chr20_-_32543497 2.62 ENSDART00000026635
nr2e1
nuclear receptor subfamily 2, group E, member 1
chr4_+_12618256 2.60 ENSDART00000112860
ENSDART00000134362
lmo3
LIM domain only 3
chr23_-_7892862 2.58 ENSDART00000157612
ENSDART00000165427
myt1b
myelin transcription factor 1b
chr9_-_23081250 2.55

chr9_+_308260 2.54 ENSDART00000163474
stac3
SH3 and cysteine rich domain 3
chr21_+_23916512 2.53 ENSDART00000145541
ENSDART00000065599
ENSDART00000112869
cadm1a
cell adhesion molecule 1a
chr14_+_21531709 2.50 ENSDART00000144367
ctbp1
C-terminal binding protein 1
chr14_-_36523075 2.49 ENSDART00000109293
rnf130
ring finger protein 130
chr8_-_44305494 2.49 ENSDART00000098520
fzd10
frizzled class receptor 10
chr23_-_27226280 2.49 ENSDART00000141305
si:dkey-157g16.6
si:dkey-157g16.6
chr16_+_5625301 2.48

chr19_-_23037220 2.47 ENSDART00000090669
pleca
plectin a
chr3_+_32394653 2.45 ENSDART00000150897
si:ch73-367p23.2
si:ch73-367p23.2
chr12_-_5085227 2.42 ENSDART00000160729
rbp4
retinol binding protein 4, plasma
chr14_+_34683602 2.40 ENSDART00000172171
ebf1a
early B-cell factor 1a
chr9_+_42019770 2.40 ENSDART00000097295
col18a1a
collagen type XVIII alpha 1 chain a
chr18_+_9413588 2.39 ENSDART00000061886
sema3ab
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab
chr24_+_9605832 2.35 ENSDART00000131891
tmem108
transmembrane protein 108
chr5_-_36647498 2.34 ENSDART00000112312
lrch2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr3_+_37433008 2.32 ENSDART00000055225
wnt9b
wingless-type MMTV integration site family, member 9B
chr9_-_7560915 2.32 ENSDART00000081553
desma
desmin a
chr11_-_41357639 2.31 ENSDART00000055709
her2
hairy-related 2
chr7_+_6814828 2.30 ENSDART00000001649
actn3b
actinin alpha 3b
chr22_-_17652938 2.28 ENSDART00000139911
tjp3
tight junction protein 3
chr7_+_21455138 2.28 ENSDART00000173992
kdm6ba
lysine (K)-specific demethylase 6B, a
chr3_-_55956030 2.26 ENSDART00000158163
srl
sarcalumenin
chr4_+_17428131 2.24 ENSDART00000056005
ascl1a
achaete-scute family bHLH transcription factor 1a
KN149968v1_+_15749 2.24 ENSDART00000168977
ENSDARG00000102503
ENSDARG00000102503
chr9_-_34491458 2.20 ENSDART00000049805
ildr2
immunoglobulin-like domain containing receptor 2
KN149932v1_+_27584 2.19

chr2_-_20941256 2.17 ENSDART00000114199
si:ch211-267e7.3
si:ch211-267e7.3
chr5_+_45477559 2.17 ENSDART00000138055
iqgap2
IQ motif containing GTPase activating protein 2
chr1_-_54319943 2.17 ENSDART00000152666
slc25a23a
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23a
chr12_-_36138709 2.16 ENSDART00000130985
st6galnac
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase
chr10_-_39210658 2.16 ENSDART00000150193
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr4_+_10065500 2.16 ENSDART00000026492
flncb
filamin C, gamma b (actin binding protein 280)
chr10_-_42032702 2.16

chr20_-_19646761 2.15

chr24_-_3334678 2.13

chr13_-_31310439 2.13 ENSDART00000076571
rtn1a
reticulon 1a
chr23_-_39956151 2.13 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr21_+_27346176 2.09 ENSDART00000005682
actn3a
actinin alpha 3a
chr1_-_10822278 2.08 ENSDART00000091205
sdk1b
sidekick cell adhesion molecule 1b
chr16_+_43249142 2.07 ENSDART00000154493
adam22
ADAM metallopeptidase domain 22
chr10_+_15819085 2.07 ENSDART00000114483
apba1b
amyloid beta (A4) precursor protein-binding, family A, member 1b
chr5_-_28090077 2.06

chr11_+_14142126 2.05 ENSDART00000102520
palm1a
paralemmin 1a
chr25_+_35179025 2.05 ENSDART00000149768
kif21a
kinesin family member 21A
chr14_+_11151485 2.04 ENSDART00000169202
si:ch211-153b23.5
si:ch211-153b23.5
chr5_-_36237656 2.03 ENSDART00000032481
ckma
creatine kinase, muscle a
chr11_-_5868257 2.02 ENSDART00000104360
gamt
guanidinoacetate N-methyltransferase
chr5_+_36180981 2.02 ENSDART00000087191
mark4a
MAP/microtubule affinity-regulating kinase 4a
chr11_+_20269868 2.01 ENSDART00000104022
cdh4
cadherin 4, type 1, R-cadherin (retinal)
chr16_+_24057260 2.00 ENSDART00000132742
ENSDART00000145330
apoc1
apolipoprotein C-I
chr16_+_46435014 1.99 ENSDART00000144000
rpz2
rapunzel 2
chr21_-_17259886 1.99 ENSDART00000114877
gfi1b
growth factor independent 1B transcription repressor
chr11_+_666006 1.98 ENSDART00000130839
timp4.1
TIMP metallopeptidase inhibitor 4, tandem duplicate 1
chr17_-_6219019 1.98

chr23_-_31585883 1.98 ENSDART00000157511
eya4
EYA transcriptional coactivator and phosphatase 4
chr9_+_9133904 1.98 ENSDART00000165932
sik1
salt-inducible kinase 1
chr16_-_20506304 1.97 ENSDART00000134980
si:dkeyp-86h10.3
si:dkeyp-86h10.3
chr14_+_26247858 1.97 ENSDART00000105932
si:dkeyp-110e4.11
si:dkeyp-110e4.11
chr22_+_4722336 1.97 ENSDART00000138967
atcaya
ataxia, cerebellar, Cayman type a
chr8_-_23172938 1.93 ENSDART00000141090
si:ch211-196c10.15
si:ch211-196c10.15
chr22_-_613948 1.90 ENSDART00000148692
apobec2a
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a
chr16_+_5625552 1.90

chr15_-_35563367 1.88

chr15_+_9351511 1.88 ENSDART00000144381
sgcg
sarcoglycan, gamma
chr16_+_3090170 1.88 ENSDART00000110395
limd1a
LIM domains containing 1a
chr22_+_12327849 1.88 ENSDART00000178678
FO704572.1
ENSDARG00000106890
chr16_-_42040346 1.88 ENSDART00000169313
pycard
PYD and CARD domain containing
chr21_+_4964891 1.86 ENSDART00000102572
thbs4b
thrombospondin 4b
chr19_-_22182031 1.86 ENSDART00000104279
znf516
zinc finger protein 516
chr2_-_44402486 1.86 ENSDART00000011188
ENSDART00000093298
atp1a2a
ATPase, Na+/K+ transporting, alpha 2a polypeptide
chr24_-_2278409 1.85

chr3_-_38550961 1.84 ENSDART00000155042
mpp3a
membrane protein, palmitoylated 3a (MAGUK p55 subfamily member 3)
chr16_-_26803204 1.83 ENSDART00000162665
esrp1
epithelial splicing regulatory protein 1
chr23_-_15807415 1.82 ENSDART00000178557
BX005011.3
ENSDARG00000108083
chr3_-_39313029 1.81 ENSDART00000156123
CU464118.1
ENSDARG00000097747
chr15_-_1858350 1.81 ENSDART00000082026
mmp28
matrix metallopeptidase 28
chr16_-_14463682 1.81 ENSDART00000011224
itga10
integrin, alpha 10
chr23_+_20183765 1.80 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr20_-_42805703 1.80 ENSDART00000045816
plg
plasminogen
chr6_-_16541104 1.79

chr1_-_48853800 1.79 ENSDART00000137357
zgc:175214
zgc:175214
chr21_-_34623741 1.79 ENSDART00000023038
dacha
dachshund a
chr11_-_9479592 1.79 ENSDART00000175829
CU179643.1
ENSDARG00000086489
chr18_-_15404998 1.78 ENSDART00000031752
rfx4
regulatory factor X, 4
chr2_-_42643045 1.78 ENSDART00000139929
esyt2a
extended synaptotagmin-like protein 2a
chr13_-_31165867 1.78 ENSDART00000030946
prdm8
PR domain containing 8
chr17_+_8166167 1.77 ENSDART00000169900
cdc42bpaa
CDC42 binding protein kinase alpha (DMPK-like) a
chr12_-_4767887 1.76 ENSDART00000167490
mapta
microtubule-associated protein tau a
chr20_-_22036656 1.75 ENSDART00000152290
daam1b
dishevelled associated activator of morphogenesis 1b
chr25_+_14411153 1.75 ENSDART00000015681
dbx1b
developing brain homeobox 1b
chr14_-_33596430 1.74 ENSDART00000112438
si:ch73-335m24.5
si:ch73-335m24.5
chr13_-_24181106 1.74 ENSDART00000004420
rab4a
RAB4a, member RAS oncogene family
chr23_+_36032206 1.73 ENSDART00000103132
hoxc4a
homeobox C4a
chr23_-_27226387 1.73 ENSDART00000141305
si:dkey-157g16.6
si:dkey-157g16.6
chr24_-_33817036 1.73 ENSDART00000079292
cavin4b
caveolae associated protein 4b
chr4_+_12618485 1.73 ENSDART00000112860
lmo3
LIM domain only 3
chr5_+_53854279 1.72 ENSDART00000165889
tprn
taperin
chr7_+_31608828 1.72 ENSDART00000138491
mybpc3
myosin binding protein C, cardiac
chr6_-_586251 1.71 ENSDART00000148867
ENSDART00000149414
ENSDART00000149248
lgals2b
lectin, galactoside-binding, soluble, 2b
chr20_+_34497817 1.71 ENSDART00000061632
fam129aa
family with sequence similarity 129, member Aa
chr10_-_36462538 1.71 ENSDART00000161823
ubl3a
ubiquitin-like 3a
chr10_+_16634200 1.71 ENSDART00000101142
chsy3
chondroitin sulfate synthase 3
chr4_-_4825948 1.70 ENSDART00000141539
coa6
cytochrome c oxidase assembly factor 6
chr18_-_34166500 1.70 ENSDART00000079341
plch1
phospholipase C, eta 1
chr10_-_10374032 1.70 ENSDART00000134929
BX323065.1
ENSDARG00000095365
chr4_-_14330048 1.69 ENSDART00000091151
nell2b
neural EGFL like 2b
chr6_+_1873957 1.69

chr11_-_6960107 1.69 ENSDART00000171255
COMP
cartilage oligomeric matrix protein
chr5_-_23697487 1.69 ENSDART00000013309
sox19a
SRY (sex determining region Y)-box 19a
KN150178v1_-_23644 1.68 ENSDART00000165583
soul3
heme-binding protein soul3
chr16_+_23172295 1.67 ENSDART00000167518
ENSDART00000161087
efna3b
ephrin-A3b
chr14_-_2027432 1.67

chr1_+_38834751 1.66 ENSDART00000137676
tenm3
teneurin transmembrane protein 3
chr12_-_25825072 1.66

chr12_+_22734974 1.66 ENSDART00000130594
afap1
actin filament associated protein 1
chr24_+_20414578 1.66 ENSDART00000131677
hhatlb
hedgehog acyltransferase-like, b
chr1_+_51925783 1.65 ENSDART00000167514
abca1a
ATP-binding cassette, sub-family A (ABC1), member 1A
chr6_-_32718634 1.65 ENSDART00000175666
mafaa
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa
chr14_-_16023198 1.64

chr9_-_49834232 1.64

chr23_+_14058972 1.63 ENSDART00000090864
lmod3
leiomodin 3 (fetal)
chr15_+_28435937 1.63 ENSDART00000142298
slc43a2a
solute carrier family 43 (amino acid system L transporter), member 2a
chr22_+_21997000 1.62 ENSDART00000046174
gna15.1
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1
chr11_-_30105047 1.62 ENSDART00000030794
tmem169a
transmembrane protein 169a
chr14_+_36156947 1.61

KN150495v1_-_20497 1.60

chr9_-_32942783 1.60 ENSDART00000060006
olig2
oligodendrocyte lineage transcription factor 2
chr23_+_6861489 1.60 ENSDART00000092131
si:ch211-117c9.5
si:ch211-117c9.5
chr23_+_36002332 1.60 ENSDART00000103139
hoxc8a
homeobox C8a
chr16_+_28819826 1.60 ENSDART00000103340
s100v1
S100 calcium binding protein V1
chr22_+_38096040 1.60 ENSDART00000097533
wwtr1
WW domain containing transcription regulator 1
chr14_+_38445969 1.60 ENSDART00000164440
si:ch211-195b11.3
si:ch211-195b11.3
chr9_-_18561215 1.59 ENSDART00000084668
enox1
ecto-NOX disulfide-thiol exchanger 1
chr21_-_5852663 1.58 ENSDART00000130521
CACFD1
calcium channel flower domain containing 1
chr3_-_27944852 1.58 ENSDART00000122037
rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr22_+_24131239 1.58 ENSDART00000159165
b3galt2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr2_-_30071872 1.58 ENSDART00000056747
shhb
sonic hedgehog b
chr7_+_16583234 1.57 ENSDART00000173580
nav2a
neuron navigator 2a
chr8_+_23464087 1.57 ENSDART00000026316
sema3gb
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Gb
chr25_+_24193604 1.56 ENSDART00000083407
b4galnt4a
beta-1,4-N-acetyl-galactosaminyl transferase 4a
chr23_-_3466041 1.56 ENSDART00000002309
mafba
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
chr6_+_59762717 1.55 ENSDART00000050457
zgc:65895
zgc:65895
chr15_+_7190427 1.55 ENSDART00000109394
her13
hairy-related 13
chr5_+_38237115 1.55 ENSDART00000160236
fras1
Fraser extracellular matrix complex subunit 1
chr16_+_24032160 1.55 ENSDART00000103190
apoa4b.2
apolipoprotein A-IV b, tandem duplicate 2
chr4_+_8637319 1.55

chr10_-_39211281 1.55 ENSDART00000148825
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr22_+_16282153 1.54 ENSDART00000162685
ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr1_-_16894589 1.53 ENSDART00000039917
acsl1a
acyl-CoA synthetase long-chain family member 1a
chr21_-_7277655 1.53 ENSDART00000056561
s100z
S100 calcium binding protein Z
chr2_+_21342233 1.53 ENSDART00000062563
rreb1b
ras responsive element binding protein 1b
chr4_+_21166170 1.53 ENSDART00000036886
nav3
neuron navigator 3
chr25_-_13737344 1.52

chr7_+_31567166 1.52 ENSDART00000099785
ENSDART00000122506
mybpc3
myosin binding protein C, cardiac
chr11_-_25592102 1.52 ENSDART00000103549
skib
v-ski avian sarcoma viral oncogene homolog b
chr6_+_45917081 1.52 ENSDART00000149450
ENSDART00000149642
h6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr10_+_34377959 1.52

chr14_+_34683695 1.51 ENSDART00000170631
ebf1a
early B-cell factor 1a
chr5_+_37053530 1.51 ENSDART00000161051
sptbn2
spectrin, beta, non-erythrocytic 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.6 GO:0060262 N-terminal protein palmitoylation(GO:0006500) negative regulation of lipoprotein metabolic process(GO:0050748) regulation of N-terminal protein palmitoylation(GO:0060254) negative regulation of N-terminal protein palmitoylation(GO:0060262) negative regulation of protein lipidation(GO:1903060)
1.1 4.5 GO:0003210 cardiac atrium formation(GO:0003210)
1.1 6.4 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
1.1 3.2 GO:0021742 abducens nucleus development(GO:0021742)
1.0 2.9 GO:0010084 specification of organ axis polarity(GO:0010084)
0.8 2.5 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.8 2.4 GO:0097484 dendrite extension(GO:0097484)
0.8 3.8 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
0.8 3.0 GO:0071691 cardiac muscle thin filament assembly(GO:0071691)
0.7 2.2 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.7 8.1 GO:0033292 T-tubule organization(GO:0033292)
0.7 2.8 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.7 7.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.7 2.1 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577) regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.7 2.0 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.7 2.0 GO:0006601 creatine metabolic process(GO:0006600) creatine biosynthetic process(GO:0006601)
0.6 2.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.6 1.9 GO:0051101 regulation of DNA binding(GO:0051101)
0.6 1.8 GO:0042730 fibrinolysis(GO:0042730)
0.6 1.7 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.6 2.2 GO:0032371 regulation of sterol transport(GO:0032371) regulation of cholesterol transport(GO:0032374)
0.5 2.1 GO:0098900 regulation of action potential(GO:0098900)
0.5 1.6 GO:0007624 ultradian rhythm(GO:0007624)
0.5 1.5 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.5 3.0 GO:1902946 protein localization to early endosome(GO:1902946)
0.5 3.0 GO:2001240 histone dephosphorylation(GO:0016576) negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.5 2.8 GO:0006798 polyphosphate metabolic process(GO:0006797) polyphosphate catabolic process(GO:0006798)
0.5 1.9 GO:0035989 tendon development(GO:0035989)
0.4 1.3 GO:0097104 presynaptic membrane organization(GO:0097090) postsynaptic membrane assembly(GO:0097104) presynaptic membrane assembly(GO:0097105)
0.4 1.8 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
0.4 0.4 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.4 1.3 GO:0030431 temperature homeostasis(GO:0001659) sleep(GO:0030431)
0.4 1.3 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.4 1.2 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.4 2.3 GO:0010882 regulation of cardiac muscle contraction by calcium ion signaling(GO:0010882)
0.4 1.5 GO:0016199 axon midline choice point recognition(GO:0016199)
0.4 1.1 GO:0097186 enamel mineralization(GO:0070166) amelogenesis(GO:0097186)
0.4 4.8 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.4 0.7 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.3 2.0 GO:0046532 regulation of photoreceptor cell differentiation(GO:0046532)
0.3 3.7 GO:0060956 cardiac endothelial cell differentiation(GO:0003348) endocardial cell differentiation(GO:0060956)
0.3 4.3 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.3 1.6 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.3 1.3 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.3 2.3 GO:0030104 water homeostasis(GO:0030104)
0.3 2.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.3 1.9 GO:0061298 retina vasculature development in camera-type eye(GO:0061298)
0.3 1.6 GO:0090200 regulation of mitochondrial membrane potential(GO:0051881) membrane depolarization(GO:0051899) regulation of release of cytochrome c from mitochondria(GO:0090199) positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.3 1.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.3 1.6 GO:0051124 synaptic growth at neuromuscular junction(GO:0051124)
0.3 1.8 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.3 2.4 GO:0046865 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.3 0.9 GO:0021661 rhombomere 4 development(GO:0021570) rhombomere 4 morphogenesis(GO:0021661)
0.3 0.9 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 1.8 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.3 1.5 GO:0035860 esophagus smooth muscle contraction(GO:0014846) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.3 0.9 GO:0042590 antigen processing and presentation of exogenous peptide antigen(GO:0002478) antigen processing and presentation of exogenous antigen(GO:0019884) antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.3 1.1 GO:0071635 transforming growth factor beta activation(GO:0036363) transforming growth factor beta production(GO:0071604) regulation of transforming growth factor beta production(GO:0071634) negative regulation of transforming growth factor beta production(GO:0071635) regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
0.3 1.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.3 1.7 GO:0007405 neuroblast proliferation(GO:0007405)
0.3 3.3 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.3 1.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.3 1.1 GO:0003334 keratinocyte development(GO:0003334)
0.3 2.4 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.3 1.9 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.3 1.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021) wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.3 0.8 GO:0030800 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclic nucleotide metabolic process(GO:0030800) negative regulation of cyclic nucleotide biosynthetic process(GO:0030803) negative regulation of nucleotide biosynthetic process(GO:0030809) negative regulation of cAMP metabolic process(GO:0030815) negative regulation of cAMP biosynthetic process(GO:0030818) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350) negative regulation of purine nucleotide biosynthetic process(GO:1900372)
0.3 3.7 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.3 0.8 GO:0061550 cranial ganglion development(GO:0061550)
0.3 2.0 GO:0006603 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.3 0.8 GO:0007289 spermatid nucleus differentiation(GO:0007289) sperm chromatin condensation(GO:0035092) spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2 0.7 GO:0016203 muscle attachment(GO:0016203)
0.2 1.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 1.5 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 1.2 GO:0050975 sensory perception of touch(GO:0050975)
0.2 1.9 GO:0032185 septin ring organization(GO:0031106) septin cytoskeleton organization(GO:0032185)
0.2 0.9 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 1.8 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.2 1.3 GO:0034672 anterior/posterior pattern specification involved in pronephros development(GO:0034672) anterior/posterior pattern specification involved in kidney development(GO:0072098)
0.2 4.5 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 1.2 GO:0001964 startle response(GO:0001964)
0.2 4.3 GO:0030199 collagen fibril organization(GO:0030199)
0.2 0.6 GO:0003241 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.2 2.9 GO:0006942 regulation of striated muscle contraction(GO:0006942)
0.2 1.6 GO:0030183 B cell differentiation(GO:0030183)
0.2 0.2 GO:0035479 angioblast cell migration from lateral mesoderm to midline(GO:0035479)
0.2 1.3 GO:0021754 facial nucleus development(GO:0021754)
0.2 2.6 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.2 0.6 GO:0050810 positive regulation of steroid metabolic process(GO:0045940) regulation of steroid biosynthetic process(GO:0050810)
0.2 1.6 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.2 0.9 GO:0021576 hindbrain formation(GO:0021576)
0.2 1.9 GO:0072576 liver morphogenesis(GO:0072576)
0.2 1.0 GO:0033198 response to ATP(GO:0033198)
0.2 3.3 GO:0051764 actin crosslink formation(GO:0051764)
0.2 0.5 GO:0010996 response to auditory stimulus(GO:0010996)
0.2 1.7 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.2 1.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 0.7 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.2 4.9 GO:0007416 synapse assembly(GO:0007416)
0.2 0.5 GO:0097378 interneuron axon guidance(GO:0097376) spinal cord interneuron axon guidance(GO:0097377) dorsal spinal cord interneuron axon guidance(GO:0097378)
0.2 2.1 GO:0097320 membrane tubulation(GO:0097320)
0.2 0.5 GO:0003207 cardiac chamber formation(GO:0003207)
0.2 3.1 GO:0003009 skeletal muscle contraction(GO:0003009)
0.2 2.1 GO:0045471 response to ethanol(GO:0045471)
0.2 0.9 GO:1904103 regulation of convergent extension involved in gastrulation(GO:1904103)
0.2 1.1 GO:0016572 histone phosphorylation(GO:0016572)
0.2 0.8 GO:0090527 actin filament reorganization(GO:0090527)
0.2 0.5 GO:0099560 synaptic membrane adhesion(GO:0099560)
0.2 2.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.1 GO:0019374 galactosylceramide metabolic process(GO:0006681) galactolipid metabolic process(GO:0019374) short-chain fatty acid metabolic process(GO:0046459)
0.2 0.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.2 0.9 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 0.8 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.2 3.3 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.2 1.5 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.2 0.6 GO:0060143 positive regulation of syncytium formation by plasma membrane fusion(GO:0060143) positive regulation of myoblast fusion(GO:1901741)
0.2 0.6 GO:0072506 regulation of fat cell differentiation(GO:0045598) phosphate ion homeostasis(GO:0055062) trivalent inorganic anion homeostasis(GO:0072506)
0.2 0.8 GO:1901381 positive regulation of sodium ion transport(GO:0010765) positive regulation of potassium ion transport(GO:0043268) positive regulation of potassium ion transmembrane transport(GO:1901381) positive regulation of sodium ion transmembrane transport(GO:1902307) regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288) positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.2 1.2 GO:0046185 aldehyde catabolic process(GO:0046185)
0.1 1.0 GO:1902866 regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.1 1.5 GO:0045773 positive regulation of axon extension(GO:0045773)
0.1 0.4 GO:0070084 protein initiator methionine removal(GO:0070084)
0.1 0.4 GO:0019284 L-methionine biosynthetic process from S-adenosylmethionine(GO:0019284)
0.1 3.1 GO:1903845 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845)
0.1 7.9 GO:0045666 positive regulation of neuron differentiation(GO:0045666)
0.1 2.2 GO:0030050 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 0.3 GO:0030279 negative regulation of ossification(GO:0030279)
0.1 2.0 GO:0007602 phototransduction(GO:0007602)
0.1 0.9 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1 12.5 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.1 1.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.1 1.2 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 1.5 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.1 1.4 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.4 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.6 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) succinate transport(GO:0015744) succinate transmembrane transport(GO:0071422) malate transmembrane transport(GO:0071423)
0.1 0.6 GO:0006958 humoral immune response mediated by circulating immunoglobulin(GO:0002455) complement activation, classical pathway(GO:0006958)
0.1 0.4 GO:0098943 neurotransmitter receptor transport, postsynaptic endosome to lysosome(GO:0098943)
0.1 0.5 GO:0061337 cardiac conduction(GO:0061337)
0.1 0.5 GO:0035908 ventral aorta development(GO:0035908) pharyngeal arch artery morphogenesis(GO:0061626)
0.1 1.5 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.1 2.2 GO:0015807 L-amino acid transport(GO:0015807)
0.1 1.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.3 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.5 GO:0006574 valine catabolic process(GO:0006574)
0.1 1.6 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.1 1.4 GO:0045332 phospholipid translocation(GO:0045332)
0.1 1.5 GO:0055008 cardiac muscle tissue morphogenesis(GO:0055008)
0.1 0.8 GO:0034389 lipid particle organization(GO:0034389)
0.1 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.1 4.7 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1 1.9 GO:0097202 activation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0006919) activation of cysteine-type endopeptidase activity(GO:0097202)
0.1 0.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 2.0 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 0.5 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.8 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.6 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365) aorta morphogenesis(GO:0035909) dorsal aorta morphogenesis(GO:0035912)
0.1 0.4 GO:0030517 negative regulation of axon extension(GO:0030517) negative regulation of axonogenesis(GO:0050771)
0.1 1.2 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 5.9 GO:0021782 glial cell development(GO:0021782)
0.1 1.7 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.1 1.3 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.2 GO:0099509 regulation of presynaptic cytosolic calcium ion concentration(GO:0099509) regulation of long-term synaptic potentiation(GO:1900271)
0.1 0.3 GO:0021703 locus ceruleus development(GO:0021703)
0.1 4.0 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 1.7 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.5 GO:0046847 filopodium assembly(GO:0046847)
0.1 0.9 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.3 GO:1901998 toxin transport(GO:1901998)
0.1 0.7 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 2.6 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.9 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 1.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.1 0.4 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 0.6 GO:0070252 actin-mediated cell contraction(GO:0070252)
0.1 0.8 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.4 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.6 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.2 GO:0046655 folic acid metabolic process(GO:0046655)
0.1 0.5 GO:0045899 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 1.2 GO:0060349 bone morphogenesis(GO:0060349)
0.1 2.1 GO:0051693 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) actin filament capping(GO:0051693)
0.1 0.6 GO:0036302 atrioventricular canal development(GO:0036302)
0.1 0.1 GO:0051660 establishment of centrosome localization(GO:0051660)
0.1 1.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 2.7 GO:0031017 exocrine pancreas development(GO:0031017) exocrine system development(GO:0035272)
0.1 0.2 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 0.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.6 GO:0021587 cerebellum morphogenesis(GO:0021587)
0.1 1.0 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.1 2.5 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.1 1.7 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.1 1.3 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.2 GO:0006582 L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.7 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.5 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.9 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 6.0 GO:0007268 chemical synaptic transmission(GO:0007268) anterograde trans-synaptic signaling(GO:0098916)
0.0 1.4 GO:1990266 granulocyte migration(GO:0097530) neutrophil migration(GO:1990266)
0.0 1.3 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.4 GO:0060036 notochord cell vacuolation(GO:0060036)
0.0 0.2 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.7 GO:0030500 regulation of bone mineralization(GO:0030500) regulation of biomineral tissue development(GO:0070167)
0.0 0.6 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 1.1 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 2.2 GO:0007492 endoderm development(GO:0007492)
0.0 1.2 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 2.0 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.5 GO:0050768 negative regulation of neurogenesis(GO:0050768)
0.0 0.6 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 1.2 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.5 GO:0043550 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 1.3 GO:0030901 midbrain development(GO:0030901)
0.0 0.5 GO:0043433 negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433)
0.0 1.4 GO:0046328 regulation of JNK cascade(GO:0046328)
0.0 0.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.2 GO:0043114 regulation of vascular permeability(GO:0043114)
0.0 1.3 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 1.7 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.0 0.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 1.1 GO:0050821 protein stabilization(GO:0050821)
0.0 1.9 GO:0048738 cardiac muscle tissue development(GO:0048738)
0.0 1.3 GO:0009142 nucleoside triphosphate biosynthetic process(GO:0009142)
0.0 1.2 GO:0006906 vesicle fusion(GO:0006906)
0.0 0.6 GO:0043049 otic placode formation(GO:0043049)
0.0 1.4 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 1.5 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.3 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 1.2 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.0 1.2 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.0 0.1 GO:0071236 response to antibiotic(GO:0046677) cellular response to antibiotic(GO:0071236) cellular response to toxic substance(GO:0097237)
0.0 1.0 GO:0007601 visual perception(GO:0007601)
0.0 0.3 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 0.2 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.1 GO:0051048 negative regulation of secretion(GO:0051048) negative regulation of secretion by cell(GO:1903531)
0.0 1.1 GO:0018108 peptidyl-tyrosine phosphorylation(GO:0018108)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.3 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.1 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0019934 cGMP-mediated signaling(GO:0019934) positive regulation of oocyte development(GO:0060282)
0.0 1.3 GO:0008544 epidermis development(GO:0008544)
0.0 0.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.3 GO:0043171 peptide catabolic process(GO:0043171)
0.0 0.7 GO:0021854 limbic system development(GO:0021761) hypothalamus development(GO:0021854)
0.0 0.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 0.1 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.0 0.1 GO:0048898 anterior lateral line system development(GO:0048898) anterior lateral line development(GO:0048899)
0.0 0.0 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0036065 fucosylation(GO:0036065)
0.0 0.3 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.6 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 2.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.0 GO:0010942 positive regulation of cell death(GO:0010942) positive regulation of apoptotic process(GO:0043065) positive regulation of programmed cell death(GO:0043068)
0.0 0.9 GO:0051216 cartilage development(GO:0051216) connective tissue development(GO:0061448)
0.0 0.1 GO:0048546 digestive tract morphogenesis(GO:0048546)
0.0 0.4 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.4 GO:0090307 mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0 1.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 2.0 GO:0006897 endocytosis(GO:0006897)
0.0 0.3 GO:0042552 myelination(GO:0042552)
0.0 0.1 GO:0048311 mitochondrion distribution(GO:0048311)
0.0 0.9 GO:0006869 lipid transport(GO:0006869)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 1.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.8 6.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.6 6.2 GO:0031430 M band(GO:0031430)
0.6 1.7 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.5 1.9 GO:0061702 inflammasome complex(GO:0061702)
0.5 2.3 GO:0008091 spectrin(GO:0008091)
0.4 2.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.4 3.3 GO:0030315 T-tubule(GO:0030315)
0.3 1.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.3 2.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.3 0.9 GO:0042709 succinate-CoA ligase complex(GO:0042709)
0.3 6.0 GO:0005861 troponin complex(GO:0005861)
0.2 2.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.2 1.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 2.5 GO:0030056 hemidesmosome(GO:0030056)
0.2 1.1 GO:0005883 neurofilament(GO:0005883)
0.2 0.8 GO:0033263 CORVET complex(GO:0033263)
0.2 8.6 GO:0014069 postsynaptic density(GO:0014069)
0.2 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 1.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 7.0 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.2 2.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.2 2.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 0.3 GO:0070938 contractile ring(GO:0070938)
0.1 8.4 GO:0005581 collagen trimer(GO:0005581)
0.1 1.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 4.8 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.1 4.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 0.5 GO:0070062 extracellular exosome(GO:0070062)
0.1 1.1 GO:0030057 desmosome(GO:0030057)
0.1 6.5 GO:0042641 actomyosin(GO:0042641)
0.1 6.3 GO:0030018 Z disc(GO:0030018)
0.1 0.7 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.6 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.7 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.1 1.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.7 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 3.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 3.0 GO:0030426 growth cone(GO:0030426)
0.1 2.9 GO:0008305 integrin complex(GO:0008305)
0.1 1.0 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 1.0 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 3.7 GO:0016459 myosin complex(GO:0016459)
0.1 1.8 GO:0045095 keratin filament(GO:0045095)
0.1 1.2 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.4 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 3.4 GO:0005882 intermediate filament(GO:0005882)
0.1 1.7 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 1.0 GO:0043195 terminal bouton(GO:0043195)
0.1 0.4 GO:0002102 podosome(GO:0002102)
0.1 0.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.4 GO:0001650 fibrillar center(GO:0001650)
0.1 0.4 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 36.8 GO:0005615 extracellular space(GO:0005615)
0.1 4.9 GO:0030425 dendrite(GO:0030425)
0.1 1.8 GO:0016342 catenin complex(GO:0016342)
0.1 0.5 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.1 3.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.8 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 5.7 GO:0030424 axon(GO:0030424)
0.1 2.1 GO:0005924 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.1 1.4 GO:0030017 sarcomere(GO:0030017)
0.0 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.2 GO:0031201 SNARE complex(GO:0031201)
0.0 12.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 1.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 6.6 GO:0045202 synapse(GO:0045202)
0.0 1.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0036477 somatodendritic compartment(GO:0036477) neuronal cell body(GO:0043025)
0.0 1.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.0 GO:0043235 receptor complex(GO:0043235)
0.0 7.7 GO:0005576 extracellular region(GO:0005576)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.4 GO:0043005 neuron projection(GO:0043005)
0.0 6.9 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.5 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.5 GO:0030027 lamellipodium(GO:0030027)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.6 GO:0070161 adherens junction(GO:0005912) anchoring junction(GO:0070161)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.6 1.9 GO:0004126 cytidine deaminase activity(GO:0004126)
0.6 1.9 GO:0032090 Pyrin domain binding(GO:0032090)
0.6 2.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.6 1.7 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.6 4.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.5 1.6 GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity(GO:0033842)
0.5 1.5 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.5 2.4 GO:0034632 retinol transporter activity(GO:0034632)
0.5 2.8 GO:0004309 exopolyphosphatase activity(GO:0004309)
0.5 6.4 GO:0038191 neuropilin binding(GO:0038191)
0.4 1.7 GO:0016936 galactoside binding(GO:0016936)
0.4 1.7 GO:0042169 SH2 domain binding(GO:0042169)
0.4 6.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.4 5.5 GO:0005080 protein kinase C binding(GO:0005080)
0.4 6.5 GO:0001671 ATPase activator activity(GO:0001671)
0.4 3.7 GO:0005113 patched binding(GO:0005113)
0.4 2.9 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.3 1.0 GO:0019215 intermediate filament binding(GO:0019215)
0.3 1.7 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.3 1.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.3 6.6 GO:0005518 collagen binding(GO:0005518)
0.3 4.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 1.5 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.3 2.9 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3 0.9 GO:0004774 succinate-CoA ligase activity(GO:0004774) succinate-CoA ligase (ADP-forming) activity(GO:0004775) succinate-CoA ligase (GDP-forming) activity(GO:0004776)
0.3 2.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.3 2.2 GO:0055102 phospholipase inhibitor activity(GO:0004859) lipase inhibitor activity(GO:0055102)
0.3 1.7 GO:0090554 phospholipid-translocating ATPase activity(GO:0004012) phosphatidylcholine-translocating ATPase activity(GO:0090554) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 1.6 GO:0005523 tropomyosin binding(GO:0005523)
0.3 2.0 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.2 3.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 1.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.2 2.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.2 4.3 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.2 5.2 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.2 0.9 GO:0051373 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.2 2.5 GO:0030506 ankyrin binding(GO:0030506)
0.2 1.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 12.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 3.0 GO:0017022 myosin binding(GO:0017022)
0.2 1.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 0.4 GO:0008556 potassium-transporting ATPase activity(GO:0008556)
0.2 0.6 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.2 1.2 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 1.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 0.8 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.2 2.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 0.8 GO:0034584 piRNA binding(GO:0034584)
0.2 2.6 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 0.6 GO:0044548 S100 protein binding(GO:0044548)
0.2 0.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 1.2 GO:0015149 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.2 1.0 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) extracellular ATP-gated cation channel activity(GO:0004931) nucleotide receptor activity(GO:0016502) ATP-gated ion channel activity(GO:0035381)
0.2 0.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 1.5 GO:0051429 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 0.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 0.8 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.2 0.8 GO:0017081 chloride channel regulator activity(GO:0017081) chloride channel inhibitor activity(GO:0019869) potassium channel inhibitor activity(GO:0019870)
0.1 12.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 2.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 1.0 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.1 2.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.6 GO:0015140 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131) malate transmembrane transporter activity(GO:0015140) succinate transmembrane transporter activity(GO:0015141)
0.1 1.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.6 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 1.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 2.1 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.1 1.0 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.4 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.6 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 3.6 GO:0005109 frizzled binding(GO:0005109)
0.1 0.6 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 1.6 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.2 GO:0042910 xenobiotic transporter activity(GO:0042910)
0.1 1.6 GO:0032452 histone demethylase activity(GO:0032452)
0.1 3.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 2.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 1.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.4 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 1.1 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 2.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.1 0.3 GO:0099528 G-protein coupled neurotransmitter receptor activity(GO:0099528)
0.1 0.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.0 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 1.3 GO:0005112 Notch binding(GO:0005112)
0.1 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 3.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 8.0 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.8 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 3.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.2 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 23.2 GO:0003779 actin binding(GO:0003779)
0.1 1.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.2 GO:0045125 bioactive lipid receptor activity(GO:0045125) lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 2.8 GO:0046332 SMAD binding(GO:0046332)
0.1 0.4 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 1.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 2.1 GO:0005347 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleoside transmembrane transporter activity(GO:0015211) purine nucleotide transmembrane transporter activity(GO:0015216)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.0 3.7 GO:0015293 symporter activity(GO:0015293)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)
0.0 4.6 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.6 GO:0016408 C-acyltransferase activity(GO:0016408)
0.0 0.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.3 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 2.3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.9 GO:0004180 carboxypeptidase activity(GO:0004180)
0.0 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.4 GO:0030332 cyclin binding(GO:0030332)
0.0 0.7 GO:0008235 metalloexopeptidase activity(GO:0008235) metalloaminopeptidase activity(GO:0070006)
0.0 2.2 GO:0051287 NAD binding(GO:0051287)
0.0 2.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.5 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 48.0 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 2.2 GO:0019838 growth factor binding(GO:0019838)
0.0 1.0 GO:0019003 GDP binding(GO:0019003)
0.0 0.4 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.9 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0022842 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.0 1.0 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 1.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.3 GO:0031267 small GTPase binding(GO:0031267)
0.0 2.4 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 1.9 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 4.5 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.3 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.2 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.5 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0019957 chemokine binding(GO:0019956) C-C chemokine binding(GO:0019957)
0.0 0.5 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0045134 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.0 0.4 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.0 4.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.0 GO:0004475 mannose-1-phosphate guanylyltransferase activity(GO:0004475) mannose-phosphate guanylyltransferase activity(GO:0008905)
0.0 1.9 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 5.6 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.2 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.4 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.0 0.3 GO:0000049 tRNA binding(GO:0000049)
0.0 1.8 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 7.1 NABA COLLAGENS Genes encoding collagen proteins
0.2 2.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 1.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.2 0.8 PID ALK2 PATHWAY ALK2 signaling events
0.1 11.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 2.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 2.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.7 PID ARF 3PATHWAY Arf1 pathway
0.1 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.7 PID ATM PATHWAY ATM pathway
0.1 6.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 2.0 PID LKB1 PATHWAY LKB1 signaling events
0.1 1.3 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 1.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.1 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 0.2 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.9 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.6 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.9 PID E2F PATHWAY E2F transcription factor network
0.0 2.9 NABA MATRISOME Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.0 0.2 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 3.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 2.4 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.3 2.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 2.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 7.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 1.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 3.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 1.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 1.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.1 1.3 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.1 4.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 5.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.0 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 2.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 1.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 4.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 0.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 0.5 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 0.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 0.6 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.1 0.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 0.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME KERATAN SULFATE KERATIN METABOLISM Genes involved in Keratan sulfate/keratin metabolism
0.0 0.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.5 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport