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Results for tcf7l1a+tcf7l1b+tcf7l2

Z-value: 1.48

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Transcription factors associated with tcf7l1a+tcf7l1b+tcf7l2

Gene Symbol Gene ID Gene Info
ENSDARG00000004415 transcription factor 7 like 2
ENSDARG00000007369 transcription factor 7 like 1b
ENSDARG00000038159 transcription factor 7 like 1a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tcf7l2dr10_dc_chr12_-_30988279_309884850.901.9e-06Click!
tcf7l1adr10_dc_chr10_-_42469083_424691130.766.3e-04Click!
tcf7l1bdr10_dc_chr8_-_52243483_522436550.731.5e-03Click!

Activity profile of tcf7l1a+tcf7l1b+tcf7l2 motif

Sorted Z-values of tcf7l1a+tcf7l1b+tcf7l2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of tcf7l1a+tcf7l1b+tcf7l2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_-_45950530 6.84 ENSDART00000060822
antifreeze protein type IV
chr5_+_41680352 5.79 ENSDART00000142855
T-box 6, like
chr7_-_54407681 4.31 ENSDART00000162795
cyclin D1
chr15_-_35563367 3.81

chr5_-_23829861 3.70 ENSDART00000051553
zinc finger protein 703
chr25_-_22089794 3.59 ENSDART00000139110
plakophilin 3a
chr1_+_16683931 3.45 ENSDART00000103262
ENSDART00000145068
ENSDART00000169619
ENSDART00000010526
FAT atypical cadherin 1a
chr14_+_23980348 3.27 ENSDART00000160984
ENSDARG00000105465
chr3_+_54876680 3.12 ENSDART00000111585
hemoglobin, beta embryonic 1.3
chr12_-_30988279 3.08 ENSDART00000122972
ENSDART00000005562
ENSDART00000031408
ENSDART00000125046
ENSDART00000009237
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr17_-_20877606 3.08 ENSDART00000088106
ankyrin 3a
chr25_+_21732255 3.07 ENSDART00000027393
creatine kinase, mitochondrial 1
chr9_-_9693163 2.92 ENSDART00000018228
glycogen synthase kinase 3 beta
chr21_-_41286846 2.83 ENSDART00000167339
muscle segment homeobox 2b
chr7_-_54407461 2.82 ENSDART00000162795
cyclin D1
chr16_+_32605735 2.64 ENSDART00000093250
POU class 3 homeobox 2b
chr23_-_22186674 2.62 ENSDART00000142474
polyhomeotic homolog 2a (Drosophila)
chr8_-_41194452 2.57 ENSDART00000165949
fumarylacetoacetate hydrolase domain containing 2A
chr3_+_26896869 2.53 ENSDART00000065495
epithelial membrane protein 2
chr1_+_25662652 2.50 ENSDART00000113020
tet methylcytosine dioxygenase 2
chr4_+_292818 2.45 ENSDART00000103659
mesogenin 1
chr10_+_32160464 2.43 ENSDART00000099880
wingless-type MMTV integration site family, member 11, related
chr1_+_46537108 2.42

chr13_+_7575753 2.38

chr21_+_45227200 2.37 ENSDART00000155681
ENSDART00000157136
transcription factor 7 (T-cell specific, HMG-box)
chr1_-_35419335 2.36 ENSDART00000037516
zinc finger protein 827
chr11_-_22966274 2.34 ENSDART00000003646
opticin
chr3_+_39425125 2.34 ENSDART00000146867
aldolase a, fructose-bisphosphate, a
chr15_-_11257445 2.30

chr9_+_44233139 2.29 ENSDART00000162406
integrin alpha 4
chr18_+_45199548 2.27

chr7_-_72500748 2.22 ENSDART00000160523
ENSDARG00000099109
chr23_-_2084541 2.21 ENSDART00000091532
neuron-derived neurotrophic factor
chr3_-_23513177 2.14 ENSDART00000078425
even-skipped-like1
chr7_+_38479571 2.10 ENSDART00000170486
coagulation factor II (thrombin)
chr6_+_30441419 2.09

chr13_-_50299821 2.08 ENSDART00000170527
ventral expressed homeobox
chr22_+_21221777 2.07 ENSDART00000079046
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr21_-_20291707 1.99 ENSDART00000079593
solute carrier family 26 (anion exchanger), member 1
chr22_-_16015935 1.97 ENSDART00000062633
sphingosine-1-phosphate receptor 1
chr7_-_37350985 1.90 ENSDART00000173523
naked cuticle homolog 1 (Drosophila)
chr19_-_9603597 1.90 ENSDART00000045245
inhibitor of growth family, member 4
chr23_-_26150495 1.87 ENSDART00000126299
GDP dissociation inhibitor 1
chr4_-_2187291 1.80 ENSDART00000150490
ENSDARG00000009262
chr16_-_8481813 1.73 ENSDART00000051166
growth factor receptor-bound protein 10b
chr9_+_17298410 1.70 ENSDART00000048548
sciellin
chr20_-_40553998 1.67 ENSDART00000075092
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr16_+_26900732 1.63 ENSDART00000042895
cadherin 17, LI cadherin (liver-intestine)
chr13_-_50299643 1.63 ENSDART00000170527
ventral expressed homeobox
chr4_-_17420378 1.62 ENSDART00000011943
phenylalanine hydroxylase
chr12_+_27444832 1.57 ENSDART00000133719
ets variant 4
chr16_-_32605560 1.55

chr19_+_30210743 1.53 ENSDART00000167803
MARCKS-like 1b
chr8_+_39525254 1.52

chr13_+_4312466 1.50 ENSDART00000156323
T, brachyury homolog b
chr13_+_28601627 1.49 ENSDART00000015773
LIM domain binding 1a
chr20_+_27194162 1.49 ENSDART00000024595
ubiquitin protein ligase E3 component n-recognin 7
chr9_-_3700395 1.48 ENSDART00000102900
Sp5 transcription factor a
chr14_+_22150325 1.47 ENSDART00000108585
ENSDART00000161776
sosondowah ankyrin repeat domain family member Ab
chr8_-_51767046 1.47 ENSDART00000007090
T-box 16
chr14_+_34154895 1.46 ENSDART00000147756
wingless-type MMTV integration site family, member 8a
chr6_+_58921655 1.45 ENSDART00000083628
DNA-damage-inducible transcript 3
chr13_-_31310439 1.45 ENSDART00000076571
reticulon 1a
chr1_-_40208544 1.42 ENSDART00000027463
H6 family homeobox 4
chr19_+_42899678 1.40 ENSDART00000076915
si:dkey-166k12.1
chr21_-_25486257 1.31 ENSDART00000110923
connector enhancer of kinase suppressor of Ras 2b
chr15_-_8333117 1.29 ENSDART00000061351
tumor necrosis factor receptor superfamily, member 19
chr5_-_28970034 1.28 ENSDART00000043259
ectonucleoside triphosphate diphosphohydrolase 2a, tandem duplicate 2
chr23_-_20837809 1.25 ENSDART00000089750
zinc finger protein 362b
chr7_-_18302231 1.25 ENSDART00000108938
Myb/SANT-like DNA-binding domain containing 1
chr20_+_25326042 1.24 ENSDART00000130494
monooxygenase, DBH-like 1
chr6_-_2294751 1.23 ENSDART00000165223
pre-B-cell leukemia homeobox 1b
chr1_-_28241500 1.23 ENSDART00000019770
glycoprotein M6Ba
chr6_-_54103765 1.23 ENSDART00000083880
hyaluronoglucosaminidase 2a
chr13_-_18704185 1.20 ENSDART00000146795
leucine zipper, putative tumor suppressor 2a
chr6_-_43806125 1.19

chr7_-_9557990 1.17 ENSDART00000055593
aldehyde dehydrogenase 1 family, member A3
chr6_-_26569321 1.17 ENSDART00000104532
SRY (sex determining region Y)-box 14
chr7_+_69418011 1.17 ENSDART00000166105
Fras1 related extracellular matrix 1a
chr8_-_41194530 1.16 ENSDART00000173055
fumarylacetoacetate hydrolase domain containing 2A
chr1_-_40208469 1.15 ENSDART00000027463
H6 family homeobox 4
chr15_-_2224784 1.15 ENSDART00000009564
short stature homeobox 2
chr8_-_18868986 1.15 ENSDART00000079840
RAR-related orphan receptor C a
chr14_-_23980261 1.15 ENSDART00000054243
D4, zinc and double PHD fingers family 2, like
chr8_-_30233470 1.12 ENSDART00000139864
zgc:162939
chr5_+_18827478 1.11 ENSDART00000089078
acetyl-CoA carboxylase beta
chr24_-_23155932 1.11

chr14_+_34151963 1.10 ENSDART00000144301
wingless-type MMTV integration site family, member 8a
chr12_+_6432058 1.07 ENSDART00000066477
dickkopf WNT signaling pathway inhibitor 1b
chr12_-_31342432 1.07 ENSDART00000148603
acyl-CoA synthetase long-chain family member 5
chr15_-_2969420 1.05

chr2_-_59293269 1.04 ENSDART00000148286
finTRIM family, member 39, pseudogene
chr20_+_22766887 1.03 ENSDART00000147520
ligand of numb-protein X 1
chr3_-_55399331 1.03 ENSDART00000162413
axin 2 (conductin, axil)
chr7_+_37105966 1.01 ENSDART00000111842
spalt-like transcription factor 1a
chr22_-_29886668 1.01 ENSDART00000125017
ENSDARG00000092881
chr20_+_23599157 0.91 ENSDART00000149922
palladin, cytoskeletal associated protein
chr20_-_35173530 0.90 ENSDART00000019196
lefty1
chr20_+_23392782 0.90

chr20_-_48677794 0.88 ENSDART00000124040
ENSDART00000148437
insulinoma-associated 1a
chr19_+_43523303 0.87 ENSDART00000167847
eukaryotic translation elongation factor 1 alpha 1, like 2
chr13_-_31516399 0.84 ENSDART00000172375
ENSDART00000125987
ENSDART00000143903
ENSDART00000158719
SIX homeobox 4a
chr20_+_22766918 0.83 ENSDART00000147520
ligand of numb-protein X 1
chr7_+_73594790 0.83 ENSDART00000123081
zgc:173552
chr3_-_34417082 0.83 ENSDART00000166623
septin 9a
chr24_+_9124068 0.82

chr17_+_23102259 0.81 ENSDART00000178403
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr18_-_39602605 0.78 ENSDART00000125116
tumor necrosis factor, alpha-induced protein 8-like 3
chr19_+_43524098 0.77 ENSDART00000129362
eukaryotic translation elongation factor 1 alpha 1, like 2
chr16_+_24046789 0.76

chr1_+_26418707 0.73 ENSDART00000161169
basonuclin 2
chr10_-_31619761 0.72 ENSDART00000023575
roundabout, axon guidance receptor, homolog 3 (Drosophila)
chr1_+_51192660 0.70 ENSDART00000052992
DAN domain family, member 5
chr2_-_53797472 0.70 ENSDART00000057053
im:7138239
chr6_+_15635696 0.69 ENSDART00000128939
IQ motif containing with AAA domain 1
chr13_-_40027211 0.69

chr24_+_11194381 0.68 ENSDART00000143171
si:dkey-12l12.1
chr14_-_25154966 0.68 ENSDART00000148652
solute carrier family 26 (anion exchanger), member 2
chr11_-_19436304 0.65 ENSDART00000110499
ataxin 7
chr16_+_5411816 0.65

chr22_-_29886840 0.64 ENSDART00000125017
ENSDARG00000092881
chr12_+_23717554 0.63 ENSDART00000152997
supervillin a
chr18_-_14868444 0.63 ENSDART00000045232
metastasis suppressor 1-like a
chr21_+_44203036 0.63

chr13_+_32987105 0.63 ENSDART00000085719
si:ch211-10a23.2
chr5_+_37113743 0.61

chr13_+_33138144 0.61 ENSDART00000002095
transmembrane protein 39B
chr5_-_41645167 0.60

chr1_+_46537333 0.60

chr3_-_55399433 0.58 ENSDART00000162413
axin 2 (conductin, axil)
chr6_-_6818925 0.58 ENSDART00000151822
tubulin, alpha 8 like 4
chr13_+_26943081 0.58 ENSDART00000146227
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr5_+_26127909 0.58 ENSDART00000098545
transmembrane protein 150Aa
chr4_+_17088146 0.57

chr6_+_15635738 0.57 ENSDART00000128939
IQ motif containing with AAA domain 1
chr20_-_9448803 0.56 ENSDART00000133000
ENSDARG00000033201
chr14_+_6655894 0.56 ENSDART00000148394
heterogeneous nuclear ribonucleoprotein A/Ba
chr20_+_41652149 0.56 ENSDART00000135715
family with sequence similarity 184, member A
chr1_-_35419273 0.54 ENSDART00000037516
zinc finger protein 827
chr24_-_35486496 0.54

chr5_-_38873781 0.54 ENSDART00000171557
anthrax toxin receptor 2a
chr1_-_42078442 0.52 ENSDART00000074618
leucine rich repeat transmembrane neuronal 1
chr1_-_7744605 0.52 ENSDART00000033917
synaptogyrin 3b
chr19_+_43468063 0.52 ENSDART00000168263
pumilio RNA-binding family member 1
chr21_-_25486330 0.51 ENSDART00000162711
connector enhancer of kinase suppressor of Ras 2b
chr13_-_31516518 0.49 ENSDART00000172375
ENSDART00000125987
ENSDART00000143903
ENSDART00000158719
SIX homeobox 4a
chr1_-_52024906 0.48 ENSDART00000150568
aprataxin
chr23_-_40059749 0.48 ENSDART00000158168
ENSDARG00000054846
chr3_+_28700619 0.48 ENSDART00000108973
fleer
chr24_+_32635139 0.47 ENSDART00000175986
ENSDARG00000105889
chr6_-_11544518 0.47 ENSDART00000151195
membrane-associated ring finger (C3HC4) 7
chr19_+_43414160 0.47 ENSDART00000033724
fatty acid binding protein 3, muscle and heart
chr3_-_28297082 0.46 ENSDART00000151546
RNA binding protein, fox-1 homolog (C. elegans) 1
chr3_-_36940675 0.45 ENSDART00000026701
tubulin, gamma 1
chr2_-_43234323 0.45 ENSDART00000084303
potassium voltage-gated channel, KQT-like subfamily, member 3
chr4_+_16721264 0.45 ENSDART00000035899
plakophilin 2
chr2_-_53797503 0.45 ENSDART00000057053
im:7138239
chr17_+_26593564 0.45 ENSDART00000159811
tetratricopeptide repeat domain 7B
chr22_-_22696091 0.45

chr11_-_39940309 0.43 ENSDART00000086287
zinc finger protein 362a
chr22_+_21221950 0.41 ENSDART00000079046
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr5_-_21578927 0.40 ENSDART00000020908
zinc finger, C4H2 domain containing
chr21_+_26576104 0.39 ENSDART00000142667
estrogen-related receptor alpha
chr6_+_51676410 0.39 ENSDART00000151565
family with sequence similarity 65, member C
chr6_-_2294717 0.39 ENSDART00000165223
pre-B-cell leukemia homeobox 1b
chr18_+_36825511 0.38 ENSDART00000098958
tetratricopeptide repeat domain 9B
chr2_-_30005139 0.38 ENSDART00000146968
canopy1
KN150672v1_+_74532 0.37

chr5_-_7591260 0.37 ENSDART00000158447
nipped-B homolog a (Drosophila)
chr3_-_23513293 0.36 ENSDART00000140264
even-skipped-like1
chr9_+_7570199 0.34 ENSDART00000081543
protein tyrosine phosphatase, receptor type, Na
chr14_-_31748733 0.34 ENSDART00000158014
si:ch211-69b22.5
chr14_+_20862466 0.34 ENSDART00000059796
ENSDARG00000019213
chr20_-_54364559 0.34

chr13_+_7575720 0.32

chr6_-_54103833 0.31 ENSDART00000083880
hyaluronoglucosaminidase 2a
chr11_-_41487157 0.31 ENSDART00000173312
abhydrolase domain containing 6a
chr9_+_50341397 0.31

chr15_+_28173909 0.30 ENSDART00000041707
unc-119 homolog a (C. elegans)
chr9_+_30183691 0.29 ENSDART00000012447
transmembrane protein 30C
chr14_+_6656015 0.27 ENSDART00000148394
heterogeneous nuclear ribonucleoprotein A/Ba
chr12_+_27444762 0.26 ENSDART00000013033
ets variant 4
chr1_-_58577305 0.26

chr23_+_26090659 0.26 ENSDART00000167427
ENSDART00000002939
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr23_+_26090616 0.25 ENSDART00000167427
ENSDART00000002939
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr3_-_2010512 0.24

chr25_+_22474108 0.24 ENSDART00000161559
stimulated by retinoic acid 6
chr9_+_7570161 0.24 ENSDART00000081543
protein tyrosine phosphatase, receptor type, Na
chr21_+_19797435 0.23 ENSDART00000147555
coiled-coil domain containing 80 like 2
chr14_-_38532216 0.22 ENSDART00000127479
glutathione reductase
chr13_+_4040744 0.22

chr3_-_26847908 0.22 ENSDART00000155396
ENSDART00000077817
nucleotide binding protein 1 (MinD homolog, E. coli)
chr12_+_27444732 0.21 ENSDART00000013033
ets variant 4
chr14_+_6655541 0.20 ENSDART00000148447
heterogeneous nuclear ribonucleoprotein A/Ba
chr8_-_12292501 0.20

chr18_-_8828500 0.18

chr9_-_28588288 0.18 ENSDART00000104317
ENSDART00000064343
Kruppel-like factor 7b
chr21_+_19797559 0.18 ENSDART00000147555
coiled-coil domain containing 80 like 2
chr3_+_41573049 0.17 ENSDART00000155440
eukaryotic translation initiation factor 3, subunit Ba
chr14_+_14759351 0.17 ENSDART00000167075
NK1 transcription factor related 2-like,b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.9 GO:0048340 paraxial mesoderm morphogenesis(GO:0048340) paraxial mesoderm formation(GO:0048341)
1.3 6.3 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) mitotic G1 DNA damage checkpoint(GO:0031571) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.8 3.1 GO:0010226 response to lithium ion(GO:0010226)
0.7 2.2 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.6 2.6 GO:0039015 spinal cord anterior/posterior patterning(GO:0021512) cell proliferation involved in pronephros development(GO:0039015) cell proliferation involved in kidney development(GO:0072111)
0.6 6.2 GO:0042661 regulation of mesodermal cell fate specification(GO:0042661)
0.6 3.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.5 2.1 GO:1900048 positive regulation of blood coagulation(GO:0030194) positive regulation of coagulation(GO:0050820) positive regulation of hemostasis(GO:1900048)
0.5 2.5 GO:0006211 5-methylcytosine catabolic process(GO:0006211) 5-methylcytosine metabolic process(GO:0019857)
0.5 2.0 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.5 1.5 GO:2001244 positive regulation of intrinsic apoptotic signaling pathway(GO:2001244)
0.5 1.9 GO:1903533 regulation of protein targeting(GO:1903533)
0.5 2.4 GO:0033151 V(D)J recombination(GO:0033151)
0.4 1.3 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.4 1.2 GO:0009713 catechol-containing compound biosynthetic process(GO:0009713) catecholamine biosynthetic process(GO:0042423)
0.4 1.2 GO:0001504 neurotransmitter uptake(GO:0001504) regulation of neurotransmitter uptake(GO:0051580) neurotransmitter reuptake(GO:0098810)
0.4 1.6 GO:0006570 tyrosine metabolic process(GO:0006570)
0.4 3.1 GO:0006599 phosphagen metabolic process(GO:0006599) phosphocreatine metabolic process(GO:0006603) phosphagen biosynthetic process(GO:0042396) phosphocreatine biosynthetic process(GO:0046314)
0.4 1.5 GO:0019532 oxalate transport(GO:0019532)
0.4 1.1 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.4 3.7 GO:0034333 adherens junction assembly(GO:0034333)
0.4 1.1 GO:0003197 endocardial cushion development(GO:0003197) hepatic duct development(GO:0061011)
0.4 1.1 GO:2000193 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747) plasma membrane long-chain fatty acid transport(GO:0015911) regulation of organic acid transport(GO:0032890) positive regulation of organic acid transport(GO:0032892) fatty acid transmembrane transport(GO:1902001) positive regulation of anion transport(GO:1903793) regulation of anion transmembrane transport(GO:1903959) positive regulation of anion transmembrane transport(GO:1903961) regulation of fatty acid transport(GO:2000191) positive regulation of fatty acid transport(GO:2000193)
0.3 2.5 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.3 1.5 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 1.7 GO:0035545 determination of left/right asymmetry in diencephalon(GO:0035462) determination of left/right asymmetry in nervous system(GO:0035545)
0.3 3.1 GO:0015671 oxygen transport(GO:0015671)
0.2 1.7 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 6.8 GO:0060030 dorsal convergence(GO:0060030)
0.2 3.1 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 1.3 GO:0033986 response to methanol(GO:0033986) cellular response to methanol(GO:0071405)
0.2 0.7 GO:0016199 axon midline choice point recognition(GO:0016199)
0.1 1.2 GO:0051013 microtubule severing(GO:0051013)
0.1 0.9 GO:0060221 retinal rod cell differentiation(GO:0060221)
0.1 1.7 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.5 GO:1901998 toxin transport(GO:1901998)
0.1 2.3 GO:0030388 thigmotaxis(GO:0001966) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.8 GO:0035108 limb morphogenesis(GO:0035108)
0.1 0.7 GO:0008272 sulfate transport(GO:0008272)
0.1 0.5 GO:0036372 opsin transport(GO:0036372)
0.1 0.6 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.5 GO:0000012 single strand break repair(GO:0000012)
0.1 2.6 GO:0001885 endothelial cell development(GO:0001885)
0.1 4.0 GO:0007043 cell-cell junction assembly(GO:0007043)
0.1 0.7 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 2.3 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.6 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.5 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 1.5 GO:0048332 mesoderm morphogenesis(GO:0048332)
0.0 0.2 GO:0071939 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.0 0.7 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.0 2.0 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.6 GO:0051014 actin filament severing(GO:0051014)
0.0 2.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.2 GO:0008016 regulation of heart contraction(GO:0008016)
0.0 0.2 GO:0003313 heart rudiment development(GO:0003313)
0.0 0.4 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.4 GO:0048665 neuron fate specification(GO:0048665)
0.0 1.7 GO:0008544 epidermis development(GO:0008544)
0.0 0.2 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.4 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.7 GO:0006414 translational elongation(GO:0006414)
0.0 0.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.6 2.6 GO:0097189 apoptotic body(GO:0097189)
0.4 3.1 GO:0005833 hemoglobin complex(GO:0005833) haptoglobin-hemoglobin complex(GO:0031838)
0.2 3.7 GO:0016363 nuclear matrix(GO:0016363)
0.2 3.1 GO:0030315 T-tubule(GO:0030315)
0.2 3.6 GO:0030057 desmosome(GO:0030057)
0.2 0.5 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 7.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 0.5 GO:0005879 axonemal microtubule(GO:0005879)
0.1 1.2 GO:0030667 secretory granule membrane(GO:0030667)
0.1 2.6 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.6 GO:0016342 catenin complex(GO:0016342)
0.1 0.4 GO:0044304 main axon(GO:0044304)
0.1 2.2 GO:0008305 integrin complex(GO:0008305)
0.1 0.4 GO:0014704 intercalated disc(GO:0014704)
0.1 0.5 GO:0070938 contractile ring(GO:0070938)
0.1 3.8 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.8 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 1.2 GO:0030496 midbody(GO:0030496)
0.0 0.1 GO:0099634 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.0 0.6 GO:0030141 secretory granule(GO:0030141)
0.0 0.2 GO:0016282 eukaryotic 43S preinitiation complex(GO:0016282)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.5 2.5 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.5 2.0 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.4 3.1 GO:0031720 haptoglobin binding(GO:0031720)
0.4 2.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.4 3.1 GO:0016775 creatine kinase activity(GO:0004111) phosphotransferase activity, nitrogenous group as acceptor(GO:0016775)
0.4 1.5 GO:0030274 LIM domain binding(GO:0030274)
0.4 1.1 GO:0039706 co-receptor binding(GO:0039706)
0.3 1.6 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.3 1.2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.3 2.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.2 1.7 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 1.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 1.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.1 1.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 1.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 1.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 1.3 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.1 3.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 5.7 GO:0045296 cadherin binding(GO:0045296)
0.1 0.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 6.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 3.7 GO:0016836 hydro-lyase activity(GO:0016836)
0.1 2.6 GO:0005109 frizzled binding(GO:0005109)
0.1 0.5 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.2 GO:0004362 glutathione-disulfide reductase activity(GO:0004362)
0.0 0.2 GO:0034632 retinol transporter activity(GO:0034632)
0.0 2.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 2.2 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.5 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.5 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.4 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 26.5 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 0.3 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.7 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 6.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.4 2.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 2.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 2.0 PID S1P S1P1 PATHWAY S1P1 pathway
0.2 2.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 2.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.8 PID LKB1 PATHWAY LKB1 signaling events
0.1 3.1 PID AP1 PATHWAY AP-1 transcription factor network
0.1 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.9 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.5 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 6.3 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.1 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.0 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.1 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.1 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 2.8 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 1.5 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.1 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.4 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.9 REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)