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Results for tead3a+tead3b

Z-value: 6.25

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Transcription factors associated with tead3a+tead3b

Gene Symbol Gene ID Gene Info
tead3b
ENSDARG00000063649 TEA domain family member 3 b
tead3a
ENSDARG00000074321 TEA domain family member 3 a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tead3bdr10_dc_chr6_+_54568649_545687230.552.6e-02Click!

Activity profile of tead3a+tead3b motif

Sorted Z-values of tead3a+tead3b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of tead3a+tead3b

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr20_-_29148810 22.40 ENSDART00000140350
thbs1b
thrombospondin 1b
chr2_-_10555152 21.77 ENSDART00000150166
gng12a
guanine nucleotide binding protein (G protein), gamma 12a
chr6_+_15141723 20.74 ENSDART00000128090
ecrg4b
esophageal cancer related gene 4b
chr1_+_53286155 17.03 ENSDART00000139625
acta1a
actin, alpha 1a, skeletal muscle
chr3_-_16387246 16.46 ENSDART00000133907
eps8l1
eps8-like1
chr9_+_21466934 14.50 ENSDART00000139620
lats2
large tumor suppressor kinase 2
chr5_-_70948223 14.35 ENSDART00000013404
ak1
adenylate kinase 1
chr6_-_39315024 14.29 ENSDART00000012644
krt4
keratin 4
chr13_+_22545318 14.13 ENSDART00000143312
zgc:193505
zgc:193505
chr13_-_46292762 14.10 ENSDART00000149125
fgfr2
fibroblast growth factor receptor 2
chr5_-_31708933 13.90 ENSDART00000123003
myhz1.1
myosin, heavy polypeptide 1.1, skeletal muscle
chr8_+_31426328 13.89 ENSDART00000135101
sepp1a
selenoprotein P, plasma, 1a
chr18_+_6551983 13.68 ENSDART00000160382
ENSDART00000171495
ENSDART00000160228
fam168a
family with sequence similarity 168, member A
chr2_+_36634309 13.61 ENSDART00000169547
ENSDART00000098417
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr15_-_20088439 13.33 ENSDART00000161379
auts2b
autism susceptibility candidate 2b
chr23_+_10552781 13.27

chr12_-_10372055 13.15 ENSDART00000052001
eef2k
eukaryotic elongation factor 2 kinase
chr14_-_30363703 13.02 ENSDART00000134098
efemp2a
EGF containing fibulin-like extracellular matrix protein 2a
chr6_+_17959219 12.89 ENSDART00000026448
evpla
envoplakin a
chr1_+_53353690 12.74 ENSDART00000126339
dla
deltaA
chr23_-_21520413 12.74 ENSDART00000044080
ENSDART00000112929
her12
hairy-related 12
chr14_+_45895103 12.45

chr2_-_29501573 12.43 ENSDART00000138073
cahz
carbonic anhydrase
chr16_-_31959111 12.43 ENSDART00000135669
rbfox1l
RNA binding protein, fox-1 homolog (C. elegans) 1-like
chr20_+_25441689 11.67 ENSDART00000063028
ctgfa
connective tissue growth factor a
chr9_-_34146631 11.60 ENSDART00000177897
AL590134.2
ENSDARG00000107869
chr3_+_36146072 11.55 ENSDART00000148444
zgc:86896
zgc:86896
chr15_-_29454583 11.33 ENSDART00000145976
serpinh1b
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b
chr3_-_55956030 11.32 ENSDART00000158163
srl
sarcalumenin
chr20_+_4567653 11.26

chr6_+_56157608 11.04 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr19_-_43037791 10.73 ENSDART00000004392
fkbp9
FK506 binding protein 9
chr13_-_28543929 10.59 ENSDART00000122754
ENSDART00000057574
nt5c2a
5'-nucleotidase, cytosolic IIa
chr22_-_15567180 10.58 ENSDART00000123125
tpm4a
tropomyosin 4a
chr1_-_18709814 10.50 ENSDART00000145224
rbm47
RNA binding motif protein 47
chr25_+_21732255 10.38 ENSDART00000027393
ckmt1
creatine kinase, mitochondrial 1
chr23_+_35984675 10.36 ENSDART00000053295
hoxc10a
homeobox C10a
chr1_-_34921848 9.85 ENSDART00000142154
frem3
Fras1 related extracellular matrix 3
chr19_-_30816780 9.83 ENSDART00000103475
agr2
anterior gradient 2
chr18_-_605558 9.80 ENSDART00000157564
wtip
WT1 interacting protein
chr1_-_19152361 9.79 ENSDART00000132958
grhprb
glyoxylate reductase/hydroxypyruvate reductase b
chr9_+_30483319 9.69 ENSDART00000148148
srpx
sushi-repeat containing protein, X-linked
chr23_+_25428372 9.62 ENSDART00000147440
fmnl3
formin-like 3
chr14_-_30467807 9.62 ENSDART00000173262
prss23
protease, serine, 23
chr11_-_11591394 9.53 ENSDART00000142208
zgc:110712
zgc:110712
chr16_+_7745309 9.48 ENSDART00000081418
ENSDART00000149404
bves
blood vessel epicardial substance
chr11_-_42096921 9.45

chr23_-_22204223 9.29 ENSDART00000079212
phc2a
polyhomeotic homolog 2a (Drosophila)
chr16_-_55320569 9.23 ENSDART00000156368
ENSDARG00000069583
ENSDARG00000069583
chr9_+_31471391 9.12 ENSDART00000010774
zic2a
zic family member 2 (odd-paired homolog, Drosophila), a
chr6_+_7092350 9.04 ENSDART00000049695
ENSDART00000136088
ENSDART00000083424
ENSDART00000125912
dzip1
DAZ interacting zinc finger protein 1
chr5_+_17120453 9.04

chr22_-_17652938 9.02 ENSDART00000139911
tjp3
tight junction protein 3
chr16_+_28819826 8.76 ENSDART00000103340
s100v1
S100 calcium binding protein V1
chr5_-_43334777 8.66 ENSDART00000142271
ENSDARG00000053091
ENSDARG00000053091
chr19_-_11096996 8.65 ENSDART00000010997
tpm3
tropomyosin 3
chr19_-_5851328 8.50 ENSDART00000133106
si:ch211-264f5.6
si:ch211-264f5.6
chr18_-_44135616 8.41 ENSDART00000087339
cdon
cell adhesion associated, oncogene regulated
chr12_+_27370834 8.40 ENSDART00000105661
meox1
mesenchyme homeobox 1
chr1_+_46537108 8.33

chr5_+_10789834 8.32

chr23_-_24468191 8.31 ENSDART00000044918
epha2b
eph receptor A2 b
chr5_-_64149931 8.30 ENSDART00000144816
lix1
limb and CNS expressed 1
chr13_-_46292975 8.21 ENSDART00000167402
ENSDART00000080914
ENSDART00000080916
fgfr2
fibroblast growth factor receptor 2
chr20_+_1887099 8.18

chr7_-_3900223 8.18 ENSDART00000019949
ndrg2
NDRG family member 2
chr25_-_26292712 8.15 ENSDART00000067114
fbxl22
F-box and leucine-rich repeat protein 22
chr20_-_8122838 8.14 ENSDART00000113993
si:ch211-232i5.1
si:ch211-232i5.1
chr16_+_46526268 8.12 ENSDART00000134734
rpz5
rapunzel 5
chr20_-_49880744 8.06 ENSDART00000025926
col12a1b
collagen, type XII, alpha 1b
chr4_-_24310846 8.05 ENSDART00000017443
celf2
cugbp, Elav-like family member 2
chr7_+_25466534 7.99

chr12_+_31558667 7.95 ENSDART00000152971
dnmbp
dynamin binding protein
chr2_-_32372801 7.94 ENSDART00000143348
BX663499.1
ENSDARG00000093778
chr19_-_33123724 7.91 ENSDART00000004034
hpca
hippocalcin
chr17_+_1058137 7.85

chr14_+_41805073 7.84 ENSDART00000074362
pcdh18b
protocadherin 18b
chr6_+_29420644 7.79 ENSDART00000065293
usp13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr6_+_7309023 7.71 ENSDART00000160128
erbb3a
erb-b2 receptor tyrosine kinase 3a
chr7_+_5372830 7.61 ENSDART00000135271
MYADM
myeloid associated differentiation marker
chr6_+_39373026 7.59 ENSDART00000157165
si:dkey-195m11.8
si:dkey-195m11.8
chr11_+_10925475 7.51 ENSDART00000064860
rbms1a
RNA binding motif, single stranded interacting protein 1a
chr7_-_71566426 7.50 ENSDART00000166724
myom1b
myomesin 1b
chr6_+_30441419 7.48

chr11_+_7148830 7.45 ENSDART00000035560
tmem38a
transmembrane protein 38A
chr7_-_37587227 7.43 ENSDART00000173552
adcy7
adenylate cyclase 7
chr15_+_5935952 7.36 ENSDART00000152520
ENSDART00000145827
sh3bgr
SH3 domain binding glutamate-rich protein
chr8_-_38126693 7.29 ENSDART00000112331
adgra2
adhesion G protein-coupled receptor A2
chr7_-_23878485 7.22 ENSDART00000005884
mmp14a
matrix metallopeptidase 14a (membrane-inserted)
chr20_-_26521700 7.18 ENSDART00000110883
akap12b
A kinase (PRKA) anchor protein 12b
chr6_+_57744081 7.17 ENSDART00000169175
SNTA1
syntrophin alpha 1
chr16_+_21109486 7.14 ENSDART00000079383
hoxa9b
homeobox A9b
chr3_-_16387615 7.14 ENSDART00000080749
ENSDART00000133824
eps8l1
eps8-like1
chr17_+_32619043 7.13 ENSDART00000087565
eva1a
eva-1 homolog A (C. elegans)
chr16_+_39396358 7.11

chr17_-_52572701 7.10 ENSDART00000060764
spred1
sprouty-related, EVH1 domain containing 1
chr14_-_25301744 7.09 ENSDART00000131886
slc25a48
solute carrier family 25, member 48
chr6_+_48138737 7.08

chr23_+_36010592 7.07 ENSDART00000137507
hoxc3a
homeo box C3a
chr20_+_26639029 7.04 ENSDART00000045397
stx11b.1
syntaxin 11b, tandem duplicate 1
chr19_-_2079482 6.99 ENSDART00000128639
ENSDARG00000086326
ENSDARG00000086326
chr19_+_5399813 6.97 ENSDART00000145749
si:dkeyp-113d7.1
si:dkeyp-113d7.1
chr5_-_18548689 6.96 ENSDART00000137802
fam214b
family with sequence similarity 214, member B
chr25_-_20886847 6.96 ENSDART00000110879
magi2b
membrane associated guanylate kinase, WW and PDZ domain containing 2b
chr23_+_20522512 6.92 ENSDART00000137294
slc35c2
solute carrier family 35 (GDP-fucose transporter), member C2
chr24_+_7607915 6.85 ENSDART00000124409
cavin1b
caveolae associated protein 1b
chr1_+_32915075 6.76 ENSDART00000114384
znf654
zinc finger protein 654
chr2_-_53210330 6.76 ENSDART00000024629
rab31
RAB31, member RAS oncogene family
chr3_-_5318206 6.72 ENSDART00000137105
myh9b
myosin, heavy chain 9b, non-muscle
chr16_+_53178713 6.67 ENSDART00000174634
CABZ01062546.1
ENSDARG00000108858
chr7_-_33994315 6.67 ENSDART00000173596
si:ch211-98n17.5
si:ch211-98n17.5
chr1_+_51706536 6.63

KN150131v1_+_59098 6.62 ENSDART00000175590
CABZ01064941.1
ENSDARG00000106550
chr2_+_26523457 6.60 ENSDART00000024662
plppr3a
phospholipid phosphatase related 3a
chr11_-_42934175 6.58 ENSDART00000172929
sptbn1
spectrin, beta, non-erythrocytic 1
chr23_-_18945009 6.57 ENSDART00000080064
CR847953.1
ENSDARG00000057403
chr3_-_39031305 6.54 ENSDART00000022393
si:dkeyp-57f11.2
si:dkeyp-57f11.2
chr7_+_67227810 6.52 ENSDART00000163840
gcshb
glycine cleavage system protein H (aminomethyl carrier), b
chr7_+_20272091 6.45 ENSDART00000052917
slc3a2a
solute carrier family 3 (amino acid transporter heavy chain), member 2a
chr18_+_18465951 6.42 ENSDART00000165079
siah1
siah E3 ubiquitin protein ligase 1
chr5_+_32191063 6.30 ENSDART00000077189
ier5l
immediate early response 5-like
chr1_-_58258428 6.28

chr1_-_24486146 6.24 ENSDART00000144711
tmem154
transmembrane protein 154
chr13_-_33137075 6.20 ENSDART00000138096
oip5-as1
oip5 antisense RNA 1
chr6_-_39315608 6.14 ENSDART00000012644
krt4
keratin 4
chr5_-_68270398 6.13 ENSDART00000161561
ENSDARG00000059093
ENSDARG00000059093
chr23_-_7740845 6.13 ENSDART00000172451
plagl2
pleiomorphic adenoma gene-like 2
chr23_+_28656263 6.10 ENSDART00000020296
nadl1.2
neural adhesion molecule L1.2
chr16_-_29342511 6.08 ENSDART00000058870
rhbg
Rh family, B glycoprotein (gene/pseudogene)
KN150670v1_-_32201 6.05

chr7_-_44332679 6.04 ENSDART00000073745
cmtm4
CKLF-like MARVEL transmembrane domain containing 4
chr9_-_1969197 6.03 ENSDART00000080608
hoxd10a
homeobox D10a
chr16_-_8481813 6.01 ENSDART00000051166
grb10b
growth factor receptor-bound protein 10b
chr24_-_16995194 5.97 ENSDART00000111079
CR376737.1
ENSDARG00000077318
chr1_+_16681778 5.96

chr5_+_69383382 5.96 ENSDART00000165570
rgs3a
regulator of G protein signaling 3a
chr14_-_5239605 5.95 ENSDART00000054877
fgf24
fibroblast growth factor 24
chr19_-_34508557 5.95 ENSDART00000160495
si:dkey-184p18.2
si:dkey-184p18.2
chr6_-_45903830 5.92 ENSDART00000025428
epha2a
eph receptor A2 a
chr24_-_32750010 5.91 ENSDART00000038364
ca2
carbonic anhydrase II
chr24_+_17056023 5.88 ENSDART00000149225
mllt10
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10
chr5_+_68410884 5.87 ENSDART00000153691
CU928129.1
ENSDARG00000097815
chr3_-_42275696 5.87 ENSDART00000167844
mafk
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
chr14_-_45883839 5.82

chr20_-_22478716 5.82 ENSDART00000110967
ENSDART00000011135
kita
v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a
chr8_-_39944817 5.81 ENSDART00000083066
asphd2
aspartate beta-hydroxylase domain containing 2
chr16_+_5466342 5.81 ENSDART00000160008
plecb
plectin b
chr9_+_38814714 5.80 ENSDART00000114728
znf148
zinc finger protein 148
chr14_+_41804998 5.75 ENSDART00000074362
pcdh18b
protocadherin 18b
chr14_-_46407410 5.72 ENSDART00000173078
si:ch211-168f7.5
si:ch211-168f7.5
chr15_+_42440802 5.71 ENSDART00000089694
tiam1b
T-cell lymphoma invasion and metastasis 1b
chr13_-_46292862 5.71 ENSDART00000150061
fgfr2
fibroblast growth factor receptor 2
chr7_-_41188744 5.71 ENSDART00000174087
smarcd3b
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3b
chr15_+_42440952 5.70 ENSDART00000089694
tiam1b
T-cell lymphoma invasion and metastasis 1b
chr12_-_7669319 5.70

chr13_-_5953330 5.69 ENSDART00000099224
dld
deltaD
chr4_-_12008472 5.67 ENSDART00000092250
btbd11a
BTB (POZ) domain containing 11a
chr1_-_8430894 5.60 ENSDART00000125596
si:ch211-14k19.8
si:ch211-14k19.8
chr17_-_20938261 5.54 ENSDART00000113655
tmem26a
transmembrane protein 26a
chr5_+_12791779 5.54

chr6_+_52064243 5.52 ENSDART00000153468
abraa
actin binding Rho activating protein a
chr23_+_36007936 5.52 ENSDART00000128533
hoxc3a
homeo box C3a
chr19_-_43038013 5.52 ENSDART00000004392
fkbp9
FK506 binding protein 9
chr19_-_9603597 5.51 ENSDART00000045245
ing4
inhibitor of growth family, member 4
chr1_-_37695900 5.49 ENSDART00000018533
hpgd
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr20_+_4567603 5.49

chr1_-_19580295 5.49 ENSDART00000146084
ndst3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr24_-_16994956 5.49 ENSDART00000111079
CR376737.1
ENSDARG00000077318
chr14_+_34440699 5.48 ENSDART00000130469
sh3tc2
SH3 domain and tetratricopeptide repeats 2
chr24_-_6048914 5.48 ENSDART00000146830
ENSDART00000021981
apbb1ip
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr17_+_38619041 5.43 ENSDART00000145147
sptb
spectrin, beta, erythrocytic
chr9_+_26292183 5.35

chr17_-_31327210 5.35 ENSDART00000154013
bahd1
bromo adjacent homology domain containing 1
chr3_+_40667131 5.34 ENSDART00000033713
arpc1b
actin related protein 2/3 complex, subunit 1B
chr7_+_63014869 5.33 ENSDART00000161436
pcdh7b
protocadherin 7b
chr7_-_50244215 5.32 ENSDART00000073910
adamtsl5
ADAMTS like 5
chr14_+_28136958 5.29

chr17_-_26893412 5.22 ENSDART00000045842
rcan3
regulator of calcineurin 3
chr7_-_26572828 5.22 ENSDART00000162241
si:ch211-107p11.3
si:ch211-107p11.3
chr20_-_38546922 5.21 ENSDART00000136303
itpkb
inositol-trisphosphate 3-kinase B
chr2_-_32572545 5.16 ENSDART00000056641
smarcd3a
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3a
chr3_+_23563620 5.15 ENSDART00000147022
hoxb7a
homeobox B7a
chr5_+_71133418 5.12

chr14_-_34431528 5.05 ENSDART00000125109
ablim3
actin binding LIM protein family, member 3
chr7_-_18894639 5.05 ENSDART00000142924
kirrel1a
kin of IRRE like a
chr2_+_22196971 5.05 ENSDART00000140012
ca8
carbonic anhydrase VIII
chr7_-_23474701 5.03 ENSDART00000048050
ITGB1BP2
integrin subunit beta 1 binding protein 2
chr11_+_10557530 5.03 ENSDART00000132365
b3gnt5a
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr12_-_26339002 5.01 ENSDART00000153214
synpo2lb
synaptopodin 2-like b
chr21_+_26660833 5.00 ENSDART00000004109
gng3
guanine nucleotide binding protein (G protein), gamma 3
chr21_+_13063614 5.00

chr19_+_46380082 5.00 ENSDART00000158781
si:ch211-153f2.7
si:ch211-153f2.7
chr6_-_43806125 4.97

chr25_-_23428527 4.95 ENSDART00000062930
phlda2
pleckstrin homology-like domain, family A, member 2
chr5_-_31301280 4.94 ENSDART00000141446
coro1cb
coronin, actin binding protein, 1Cb
chr15_-_26911132 4.94 ENSDART00000077582
pitpnm3
PITPNM family member 3
chr4_+_11312432 4.94 ENSDART00000051792
sema3aa
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Aa
chr17_-_39237265 4.90 ENSDART00000050534
crim1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr9_+_11311198 4.90 ENSDART00000110691
wnt6b
wingless-type MMTV integration site family, member 6b
chr7_+_19858190 4.88 ENSDART00000179395
ENSDART00000113793
ENSDART00000169603
zgc:114045
zgc:114045

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.1 18.3 GO:0015670 carbon dioxide transport(GO:0015670)
4.6 37.1 GO:0033278 cell proliferation in midbrain(GO:0033278)
4.3 17.1 GO:0048739 cardiac muscle fiber development(GO:0048739)
3.3 13.3 GO:0055016 hypochord development(GO:0055016)
3.1 18.5 GO:0030104 water homeostasis(GO:0030104)
2.7 18.8 GO:0072132 mesenchyme morphogenesis(GO:0072132)
2.6 13.0 GO:0048251 elastic fiber assembly(GO:0048251)
2.4 7.1 GO:2001017 regulation of retrograde axon cargo transport(GO:2001017)
2.0 6.1 GO:0072488 ammonium transmembrane transport(GO:0072488)
2.0 14.1 GO:0061056 sclerotome development(GO:0061056)
1.9 7.7 GO:0061032 visceral serous pericardium development(GO:0061032)
1.8 7.3 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
1.8 14.5 GO:0003139 secondary heart field specification(GO:0003139)
1.8 7.1 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
1.7 10.5 GO:2000742 regulation of anterior head development(GO:2000742)
1.6 9.9 GO:0009136 ADP biosynthetic process(GO:0006172) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180)
1.6 9.8 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
1.6 9.6 GO:0003160 endocardium morphogenesis(GO:0003160)
1.6 4.7 GO:0019323 pentose catabolic process(GO:0019323)
1.5 5.9 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
1.4 5.7 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
1.4 9.8 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
1.4 15.1 GO:0032986 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
1.3 4.0 GO:0061011 hepatic duct development(GO:0061011)
1.3 20.8 GO:0061300 cerebellum vasculature development(GO:0061300)
1.2 6.2 GO:0071632 optomotor response(GO:0071632)
1.2 4.8 GO:0034405 response to fluid shear stress(GO:0034405)
1.2 5.9 GO:0031581 hemidesmosome assembly(GO:0031581)
1.2 4.6 GO:0010481 ventriculo bulbo valve development(GO:0003173) epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
1.1 4.5 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.1 4.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
1.1 6.5 GO:0060142 regulation of syncytium formation by plasma membrane fusion(GO:0060142)
1.0 7.2 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
1.0 8.2 GO:0086003 cardiac muscle cell contraction(GO:0086003)
1.0 6.0 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
1.0 4.9 GO:0048755 branching morphogenesis of a nerve(GO:0048755)
1.0 5.8 GO:0014831 gastro-intestinal system smooth muscle contraction(GO:0014831)
0.9 11.0 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.9 17.1 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.9 11.4 GO:0030210 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.9 3.5 GO:0042417 dopamine metabolic process(GO:0042417)
0.9 5.2 GO:0071480 response to gamma radiation(GO:0010332) cellular response to gamma radiation(GO:0071480)
0.9 3.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.8 7.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.8 9.1 GO:0031063 regulation of histone deacetylation(GO:0031063) regulation of protein deacetylation(GO:0090311)
0.8 4.1 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) mitotic G1 DNA damage checkpoint(GO:0031571) positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.8 2.5 GO:0050854 regulation of antigen receptor-mediated signaling pathway(GO:0050854) regulation of B cell receptor signaling pathway(GO:0050855) positive regulation of antigen receptor-mediated signaling pathway(GO:0050857) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.8 4.7 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.8 3.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.8 27.5 GO:0045103 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.7 3.7 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.7 6.0 GO:0070650 actin filament bundle distribution(GO:0070650)
0.7 7.4 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.7 7.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.7 5.6 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.7 3.5 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971) axo-dendritic protein transport(GO:0099640)
0.7 2.8 GO:0015868 intracellular nucleoside transport(GO:0015859) purine nucleoside transmembrane transport(GO:0015860) purine nucleotide transport(GO:0015865) ATP transport(GO:0015867) purine ribonucleotide transport(GO:0015868) adenine nucleotide transport(GO:0051503) mitochondrial ATP transmembrane transport(GO:1990544)
0.7 3.4 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.7 2.7 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.7 4.7 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.6 9.0 GO:2000223 regulation of BMP signaling pathway involved in heart jogging(GO:2000223)
0.6 1.9 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.6 22.4 GO:2000181 negative regulation of angiogenesis(GO:0016525) negative regulation of blood vessel morphogenesis(GO:2000181)
0.6 2.4 GO:0010996 response to auditory stimulus(GO:0010996)
0.6 2.4 GO:0003315 heart rudiment formation(GO:0003315) cardioblast migration to the midline involved in heart rudiment formation(GO:0003319)
0.6 6.0 GO:0061458 gonad development(GO:0008406) negative regulation of endodermal cell fate specification(GO:0042664) reproductive structure development(GO:0048608) reproductive system development(GO:0061458)
0.6 4.0 GO:0019835 cytolysis(GO:0019835)
0.6 11.7 GO:0001757 somite specification(GO:0001757) segment specification(GO:0007379)
0.5 11.3 GO:0030199 collagen fibril organization(GO:0030199)
0.5 1.6 GO:0030431 sleep(GO:0030431) endocrine process(GO:0050886)
0.5 8.9 GO:0070570 regulation of axon regeneration(GO:0048679) regulation of neuron projection regeneration(GO:0070570)
0.5 1.5 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.5 6.0 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.5 2.0 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.5 7.3 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.5 4.4 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.5 8.4 GO:0051181 cofactor transport(GO:0051181)
0.5 1.8 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.4 3.1 GO:0010165 response to X-ray(GO:0010165)
0.4 2.2 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.4 10.4 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.4 5.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.4 6.3 GO:0002574 thrombocyte differentiation(GO:0002574)
0.4 2.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.4 10.6 GO:0036269 swimming behavior(GO:0036269)
0.4 15.5 GO:0030835 regulation of actin filament depolymerization(GO:0030834) negative regulation of actin filament depolymerization(GO:0030835) actin filament capping(GO:0051693)
0.4 9.5 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.4 3.1 GO:0021754 facial nucleus development(GO:0021754)
0.4 3.9 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.4 3.9 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.4 1.9 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.4 4.8 GO:0006884 cell volume homeostasis(GO:0006884)
0.4 2.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4 7.0 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.4 1.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 8.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.3 9.3 GO:0003094 glomerular filtration(GO:0003094)
0.3 2.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.3 4.9 GO:0048570 notochord morphogenesis(GO:0048570)
0.3 1.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.3 5.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.3 8.3 GO:0097352 autophagosome maturation(GO:0097352)
0.3 10.8 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.3 4.1 GO:0009746 response to carbohydrate(GO:0009743) response to hexose(GO:0009746) response to glucose(GO:0009749) response to monosaccharide(GO:0034284)
0.3 7.0 GO:0003146 heart jogging(GO:0003146)
0.3 4.5 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.3 3.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.3 5.1 GO:0097581 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.3 8.5 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.2 1.9 GO:0046549 retinal cone cell development(GO:0046549)
0.2 1.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 7.0 GO:0043113 receptor clustering(GO:0043113)
0.2 2.5 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.2 27.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 15.9 GO:0001756 somitogenesis(GO:0001756)
0.2 15.4 GO:0030239 myofibril assembly(GO:0030239)
0.2 5.0 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.2 2.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 1.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.2 0.8 GO:0090036 positive regulation of protein kinase A signaling(GO:0010739) bleb assembly(GO:0032060) regulation of protein kinase C signaling(GO:0090036) slow muscle cell migration(GO:1904969)
0.2 2.1 GO:0030168 platelet activation(GO:0030168)
0.2 2.7 GO:0031033 myosin filament organization(GO:0031033)
0.2 10.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.2 11.0 GO:0051402 neuron apoptotic process(GO:0051402)
0.2 3.1 GO:0001649 osteoblast differentiation(GO:0001649)
0.2 0.7 GO:0070073 regulation of melanocyte differentiation(GO:0045634) clustering of voltage-gated calcium channels(GO:0070073)
0.2 27.8 GO:0009952 anterior/posterior pattern specification(GO:0009952)
0.2 1.7 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.2 2.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.2 0.5 GO:0060911 cardiac cell fate commitment(GO:0060911)
0.2 0.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 0.9 GO:0042574 retinal metabolic process(GO:0042574)
0.2 14.4 GO:0031098 stress-activated protein kinase signaling cascade(GO:0031098)
0.1 5.2 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 4.1 GO:0001570 vasculogenesis(GO:0001570)
0.1 4.6 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.7 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 11.8 GO:0030041 actin filament polymerization(GO:0030041)
0.1 0.6 GO:0072498 embryonic skeletal joint development(GO:0072498)
0.1 7.3 GO:0051028 mRNA transport(GO:0051028)
0.1 5.5 GO:0006936 muscle contraction(GO:0006936)
0.1 7.7 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.1 4.1 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of chemotaxis(GO:0050922) negative regulation of axon guidance(GO:1902668)
0.1 1.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 18.5 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.1 5.9 GO:0021782 glial cell development(GO:0021782)
0.1 1.0 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.1 2.8 GO:0030641 regulation of cellular pH(GO:0030641)
0.1 4.4 GO:0071804 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.1 1.7 GO:0061053 somite development(GO:0061053)
0.1 0.5 GO:0043114 regulation of vascular permeability(GO:0043114)
0.1 0.5 GO:0032273 positive regulation of protein polymerization(GO:0032273)
0.1 13.1 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway(GO:0007169)
0.1 1.1 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 4.9 GO:0045165 cell fate commitment(GO:0045165)
0.1 3.3 GO:0031101 fin regeneration(GO:0031101)
0.1 3.5 GO:0010506 regulation of autophagy(GO:0010506)
0.1 6.4 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.4 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 1.5 GO:0032956 regulation of actin cytoskeleton organization(GO:0032956)
0.0 2.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.1 GO:0021510 spinal cord development(GO:0021510)
0.0 2.0 GO:0006954 inflammatory response(GO:0006954)
0.0 7.9 GO:0060271 cilium morphogenesis(GO:0060271)
0.0 0.8 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 1.9 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 1.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.1 GO:0042255 ribosome assembly(GO:0042255)
0.0 0.1 GO:1900028 negative regulation of Rac protein signal transduction(GO:0035021) wound healing, spreading of epidermal cells(GO:0035313) negative regulation of ruffle assembly(GO:1900028)
0.0 1.4 GO:0006865 amino acid transport(GO:0006865)
0.0 0.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 2.3 GO:0006914 autophagy(GO:0006914)
0.0 1.7 GO:0007015 actin filament organization(GO:0007015)
0.0 1.2 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 3.4 GO:0006897 endocytosis(GO:0006897)
0.0 3.1 GO:0006486 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.3 GO:0021854 limbic system development(GO:0021761) hypothalamus development(GO:0021854)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 15.5 GO:0008091 spectrin(GO:0008091)
2.4 26.8 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
1.4 18.8 GO:0005869 dynactin complex(GO:0005869)
1.2 4.8 GO:0070724 BMP receptor complex(GO:0070724)
1.2 9.5 GO:0016328 lateral plasma membrane(GO:0016328)
1.2 25.5 GO:0045095 keratin filament(GO:0045095)
1.1 8.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
1.1 20.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.9 15.1 GO:0071564 npBAF complex(GO:0071564)
0.8 7.7 GO:0009925 basal plasma membrane(GO:0009925)
0.7 7.5 GO:0031430 M band(GO:0031430)
0.6 7.0 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.6 1.8 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.5 5.8 GO:0030056 hemidesmosome(GO:0030056)
0.5 1.8 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.4 2.8 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.4 5.1 GO:0045178 basal part of cell(GO:0045178) basal cortex(GO:0045180)
0.3 19.9 GO:0005581 collagen trimer(GO:0005581)
0.3 17.4 GO:0005882 intermediate filament(GO:0005882)
0.3 6.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.3 20.9 GO:0030018 Z disc(GO:0030018)
0.3 16.1 GO:0016459 myosin complex(GO:0016459)
0.3 9.8 GO:0044853 caveola(GO:0005901) plasma membrane raft(GO:0044853)
0.3 20.7 GO:0016324 apical plasma membrane(GO:0016324)
0.3 2.3 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128) clathrin-coated endocytic vesicle membrane(GO:0030669)
0.3 60.3 GO:0043235 receptor complex(GO:0043235)
0.2 5.1 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 3.9 GO:0034707 chloride channel complex(GO:0034707)
0.2 2.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2 14.5 GO:0000922 spindle pole(GO:0000922)
0.2 6.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 6.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.2 1.0 GO:0005579 membrane attack complex(GO:0005579)
0.2 4.4 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.2 2.7 GO:0071565 nBAF complex(GO:0071565)
0.2 14.2 GO:0031012 extracellular matrix(GO:0031012)
0.2 1.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 9.0 GO:0005814 centriole(GO:0005814)
0.2 12.2 GO:0005795 Golgi stack(GO:0005795)
0.2 8.0 GO:0030017 sarcomere(GO:0030017)
0.1 68.4 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 65.2 GO:0005615 extracellular space(GO:0005615)
0.1 4.7 GO:0016605 PML body(GO:0016605)
0.1 1.2 GO:0000813 ESCRT I complex(GO:0000813)
0.1 7.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 2.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 1.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.1 8.8 GO:0000786 nucleosome(GO:0000786)
0.1 3.8 GO:0030425 dendrite(GO:0030425)
0.1 6.5 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 5.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 5.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 2.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.8 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.7 GO:0030904 retromer complex(GO:0030904)
0.1 3.5 GO:0005871 kinesin complex(GO:0005871)
0.1 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 5.7 GO:0005770 late endosome(GO:0005770)
0.0 15.4 GO:0045202 synapse(GO:0045202)
0.0 10.6 GO:0005576 extracellular region(GO:0005576)
0.0 9.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 9.1 GO:0005667 transcription factor complex(GO:0005667)
0.0 1.2 GO:0005925 cell-substrate adherens junction(GO:0005924) focal adhesion(GO:0005925)
0.0 1.2 GO:0030424 axon(GO:0030424)
0.0 1.1 GO:0016592 mediator complex(GO:0016592)
0.0 7.5 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 16.9 GO:0005829 cytosol(GO:0005829)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 9.8 GO:0008465 glycerate dehydrogenase activity(GO:0008465)
2.6 12.9 GO:0019215 intermediate filament binding(GO:0019215)
2.4 9.8 GO:0042134 rRNA primary transcript binding(GO:0042134)
2.3 7.0 GO:0070644 vitamin D response element binding(GO:0070644)
2.3 7.0 GO:0070699 beta-1 adrenergic receptor binding(GO:0031697) type II activin receptor binding(GO:0070699)
2.2 26.8 GO:0031681 G-protein beta-subunit binding(GO:0031681)
1.9 7.4 GO:0004016 adenylate cyclase activity(GO:0004016)
1.9 5.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
1.8 28.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
1.4 27.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.3 10.6 GO:0008253 5'-nucleotidase activity(GO:0008253)
1.2 6.0 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
1.2 4.6 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
1.1 11.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
1.1 12.6 GO:0005518 collagen binding(GO:0005518)
1.1 18.9 GO:0005112 Notch binding(GO:0005112)
1.0 2.1 GO:0005326 neurotransmitter transporter activity(GO:0005326)
1.0 5.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
1.0 14.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
1.0 5.0 GO:0042910 xenobiotic transporter activity(GO:0042910)
1.0 9.9 GO:0004017 adenylate kinase activity(GO:0004017)
0.9 3.6 GO:0031433 telethonin binding(GO:0031433) FATZ binding(GO:0051373)
0.9 7.1 GO:0034452 dynactin binding(GO:0034452)
0.9 7.1 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.9 2.6 GO:0039706 co-receptor binding(GO:0039706)
0.9 6.1 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.9 9.5 GO:0030552 cAMP binding(GO:0030552)
0.9 8.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.8 2.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.8 4.1 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.8 3.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.8 22.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.7 3.7 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.7 16.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.7 2.8 GO:0005471 ATP:ADP antiporter activity(GO:0005471) ADP transmembrane transporter activity(GO:0015217)
0.7 9.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.7 7.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.7 4.0 GO:0001223 transcription coactivator binding(GO:0001223)
0.6 10.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.6 1.8 GO:0001729 ceramide kinase activity(GO:0001729)
0.6 5.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.6 8.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.5 6.0 GO:0005158 insulin receptor binding(GO:0005158)
0.5 1.6 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.5 5.8 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.5 4.4 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.5 4.8 GO:0015379 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.5 1.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.5 1.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.4 2.7 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.4 5.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.4 2.2 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.4 5.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.4 15.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.4 2.7 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.4 1.9 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.4 16.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.4 4.9 GO:0038191 neuropilin binding(GO:0038191)
0.4 2.5 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.3 3.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.3 5.8 GO:0098631 protein binding involved in cell adhesion(GO:0098631) protein binding involved in cell-cell adhesion(GO:0098632)
0.3 2.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.3 1.8 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.3 70.7 GO:0051015 actin filament binding(GO:0051015)
0.3 3.1 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.3 13.1 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.3 4.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.3 3.3 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.2 4.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 3.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 1.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.2 2.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 7.4 GO:0005267 potassium channel activity(GO:0005267)
0.2 3.8 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 5.0 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 6.5 GO:0005109 frizzled binding(GO:0005109)
0.2 22.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.2 1.6 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 3.5 GO:0008171 O-methyltransferase activity(GO:0008171)
0.2 14.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 15.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 1.9 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439) phosphatidylinositol phosphate 5-phosphatase activity(GO:0034595)
0.1 3.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 4.4 GO:0005548 phospholipid transporter activity(GO:0005548)
0.1 2.0 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 3.3 GO:0005178 integrin binding(GO:0005178)
0.1 24.4 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 0.9 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 4.1 GO:0019955 cytokine binding(GO:0019955)
0.1 2.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.3 GO:0015232 heme transporter activity(GO:0015232)
0.1 24.1 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 4.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 15.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 2.2 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 5.1 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 7.3 GO:0031491 nucleosome binding(GO:0031491)
0.1 15.5 GO:0042802 identical protein binding(GO:0042802)
0.1 1.7 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 15.2 GO:0046982 protein heterodimerization activity(GO:0046982)
0.1 9.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 18.6 GO:0046983 protein dimerization activity(GO:0046983)
0.1 4.7 GO:0004713 protein tyrosine kinase activity(GO:0004713)
0.1 5.7 GO:1901981 phosphatidylinositol phosphate binding(GO:1901981)
0.1 1.0 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 2.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 6.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 6.4 GO:0051213 dioxygenase activity(GO:0051213)
0.1 67.4 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 2.4 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.1 2.6 GO:0005254 chloride channel activity(GO:0005254)
0.1 4.0 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 29.1 GO:0005509 calcium ion binding(GO:0005509)
0.1 7.3 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.1 2.3 GO:0030276 clathrin binding(GO:0030276)
0.0 1.2 GO:0008201 heparin binding(GO:0008201)
0.0 9.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 5.5 GO:0019901 protein kinase binding(GO:0019901)
0.0 2.5 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.1 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 7.9 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 3.5 GO:0038023 signaling receptor activity(GO:0038023)
0.0 0.6 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.8 GO:0005516 calmodulin binding(GO:0005516)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 27.7 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
2.5 7.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.7 5.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.7 5.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.7 10.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.5 28.0 PID FGF PATHWAY FGF signaling pathway
0.5 14.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.4 15.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.4 18.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.4 4.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.4 4.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.3 7.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3 11.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.3 4.8 PID ALK1 PATHWAY ALK1 signaling events
0.2 10.0 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 2.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 3.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.2 5.7 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.2 4.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.2 6.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 8.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 12.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 4.5 PID P73PATHWAY p73 transcription factor network
0.1 0.7 PID RAS PATHWAY Regulation of Ras family activation
0.1 8.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 2.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 1.7 PID ARF 3PATHWAY Arf1 pathway
0.1 1.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.4 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.1 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 28.0 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
2.2 15.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
2.0 16.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
1.9 7.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
1.2 8.5 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
1.0 15.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.9 5.5 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.9 14.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.8 16.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.8 2.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.7 5.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.7 5.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.6 5.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.6 5.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.5 6.6 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.5 5.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.4 1.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.4 12.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.4 11.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 2.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 3.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 6.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 2.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 2.2 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.1 2.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 1.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 5.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 0.8 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1 4.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 3.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1 2.8 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.1 2.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 5.9 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 1.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 4.7 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates