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Results for tefa+tefb

Z-value: 0.56

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Transcription factors associated with tefa+tefb

Gene Symbol Gene ID Gene Info
tefa
ENSDARG00000039117 TEF transcription factor, PAR bZIP family member a
tefb
ENSDARG00000098103 TEF transcription factor, PAR bZIP family member b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tefadr10_dc_chr12_-_19030156_19030162-0.852.7e-05Click!
tefbdr10_dc_chr3_-_5157662_5157883-0.621.1e-02Click!

Activity profile of tefa+tefb motif

Sorted Z-values of tefa+tefb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of tefa+tefb

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr16_-_45103102 2.07 ENSDART00000058384
gapdhs
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr3_-_31672763 1.73 ENSDART00000028270
gfap
glial fibrillary acidic protein
chr22_-_13139894 1.58 ENSDART00000105762
ahr2
aryl hydrocarbon receptor 2
chr16_+_46145286 1.34 ENSDART00000172232
sv2a
synaptic vesicle glycoprotein 2A
chr4_-_12726432 1.34 ENSDART00000132286
mgst1.2
microsomal glutathione S-transferase 1.2
chr4_-_5294280 1.28 ENSDART00000178921
SNAP91 (1 of many)
si:ch211-214j24.9
chr17_-_52020689 1.28 ENSDART00000019766
tgfb3
transforming growth factor, beta 3
chr20_-_44598129 1.22 ENSDART00000012229
fkbp1b
FK506 binding protein 1b
chr19_+_5073991 1.21 ENSDART00000151050
ENSDARG00000011076
ENSDARG00000011076
chr23_+_22977031 1.02

chr3_-_21217799 1.00 ENSDART00000114906
fam171a2a
family with sequence similarity 171, member A2a
chr15_-_40391882 0.98

chr25_-_18234069 0.97 ENSDART00000104496
dusp6
dual specificity phosphatase 6
chr3_+_29583029 0.96

chr19_-_46058954 0.94 ENSDART00000163504
trps1
trichorhinophalangeal syndrome I
chr23_+_4083697 0.94 ENSDART00000055099
b4galt5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr20_-_47521258 0.92

chr5_-_21497169 0.90 ENSDART00000143878
arhgef9a
Cdc42 guanine nucleotide exchange factor (GEF) 9a
chr16_+_17705704 0.88

chr21_+_21337628 0.87 ENSDART00000136325
rtn2b
reticulon 2b
chr8_+_8673307 0.86 ENSDART00000110854
elk1
ELK1, member of ETS oncogene family
chr24_-_39884167 0.85 ENSDART00000087441
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr3_-_11892052 0.85

chr8_+_42992323 0.82 ENSDART00000048819
rassf2a
Ras association (RalGDS/AF-6) domain family member 2a
chr2_+_24521514 0.81 ENSDART00000099546
map4l
microtubule associated protein 4 like
chr5_+_68943914 0.80 ENSDART00000159594
mthfd2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr23_+_4083748 0.79 ENSDART00000055099
b4galt5
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
chr11_-_23206021 0.79 ENSDART00000032844
plekha6
pleckstrin homology domain containing, family A member 6
chr19_-_46058895 0.77 ENSDART00000163504
trps1
trichorhinophalangeal syndrome I
chr24_+_18804086 0.77 ENSDART00000106186
prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr8_+_50498398 0.76

chr20_+_38298893 0.64 ENSDART00000022694
ehd3
EH-domain containing 3
chr19_-_22914516 0.63

chr22_-_11408859 0.63 ENSDART00000007649
mid1ip1b
MID1 interacting protein 1b
chr14_+_30568242 0.62

chr13_+_24703802 0.60 ENSDART00000101274
zgc:153981
zgc:153981
chr9_+_33979089 0.60 ENSDART00000144623
kdm6a
lysine (K)-specific demethylase 6A
chr15_-_21003820 0.60 ENSDART00000152371
usp2a
ubiquitin specific peptidase 2a
chr5_-_38224191 0.59 ENSDART00000147121
cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr6_+_16341787 0.57 ENSDART00000114667
zgc:161969
zgc:161969
chr4_-_5293599 0.52 ENSDART00000177099
SNAP91 (1 of many)
si:ch211-214j24.9
chr4_-_12915292 0.50 ENSDART00000067135
msrb3
methionine sulfoxide reductase B3
chr2_+_289138 0.50 ENSDART00000157246
znf1008
zinc finger protein 1008
chr17_-_43475725 0.49 ENSDART00000155313
hspa4l
heat shock protein 4 like
chr17_-_16079935 0.49

chr10_+_18953671 0.47 ENSDART00000135786
bnip3lb
BCL2/adenovirus E1B interacting protein 3-like b
chr17_-_8111181 0.47 ENSDART00000149873
ENSDART00000148403
ahi1
Abelson helper integration site 1
chr20_-_45757288 0.45 ENSDART00000124582
ENSDART00000100290
napbb
N-ethylmaleimide-sensitive factor attachment protein, beta b
chr5_-_20527105 0.45 ENSDART00000133461
camk2b1
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr20_-_54942216 0.44

chr5_+_22204129 0.44

KN150708v1_-_31573 0.43 ENSDART00000160040
slc16a6a
solute carrier family 16, member 6a
chr20_+_38298755 0.42 ENSDART00000022694
ehd3
EH-domain containing 3
chr7_+_10346939 0.42

chr14_+_1152700 0.42 ENSDART00000125203
hopx
HOP homeobox
chr3_-_28534446 0.40 ENSDART00000151670
fbxl16
F-box and leucine-rich repeat protein 16
chr21_+_25588388 0.39 ENSDART00000134678
ENSDARG00000078256
ENSDARG00000078256
chr5_+_14850708 0.37 ENSDART00000140990
ENSDART00000137287
pebp1
phosphatidylethanolamine binding protein 1
chr8_-_37217197 0.37 ENSDART00000178556
rbm39b
RNA binding motif protein 39b
chr8_-_29842345 0.36 ENSDART00000149297
slc20a2
solute carrier family 20 (phosphate transporter), member 2
chr17_-_17744885 0.36 ENSDART00000155261
slirp
SRA stem-loop interacting RNA binding protein
chr25_-_211879 0.34 ENSDART00000021614
srpk2
SRSF protein kinase 2
chr22_-_18466781 0.33 ENSDART00000105419
si:ch211-212d10.2
si:ch211-212d10.2
chr10_-_25629613 0.33 ENSDART00000131640
tiam1a
T-cell lymphoma invasion and metastasis 1a
chr15_+_28370102 0.32 ENSDART00000175860
myo1cb
myosin Ic, paralog b
chr23_+_34037058 0.31 ENSDART00000140666
prosc
pyridoxal phosphate binding protein
chr12_-_26291790 0.31 ENSDART00000152941
usp54b
ubiquitin specific peptidase 54b
chr25_-_10992022 0.29 ENSDART00000154748
sv2bb
synaptic vesicle glycoprotein 2Bb
chr21_+_4345150 0.27 ENSDART00000025612
phyhd1
phytanoyl-CoA dioxygenase domain containing 1
chr16_+_17706003 0.27

chr17_-_20959288 0.25 ENSDART00000006676
phyhipla
phytanoyl-CoA 2-hydroxylase interacting protein-like a
chr25_+_15257730 0.24 ENSDART00000090397
kiaa1549la
KIAA1549-like a
chr17_-_31290969 0.22

chr19_-_46058123 0.21

chr20_+_23184685 0.20 ENSDART00000132093
usp46
ubiquitin specific peptidase 46
chr19_+_8693914 0.18 ENSDART00000144925
snx27a
sorting nexin family member 27a
chr3_+_24564249 0.18 ENSDART00000111769
mkl1a
megakaryoblastic leukemia (translocation) 1a
chr12_+_18596599 0.17 ENSDART00000152935
mkl1b
megakaryoblastic leukemia (translocation) 1b
chr12_-_31369772 0.17 ENSDART00000066578
tectb
tectorin beta
chr14_+_4044357 0.16 ENSDART00000160431
dhrs13l1
dehydrogenase/reductase (SDR family) member 13 like 1
chr18_-_2580718 0.13

chr5_+_18837448 0.13

chr10_+_32949485 0.11

chr24_+_28481885 0.09 ENSDART00000079770
ENSDART00000147063
abca4a
ATP-binding cassette, sub-family A (ABC1), member 4a
chr18_-_46831863 0.07

chr19_+_7630847 0.06 ENSDART00000151758
pbxip1a
pre-B-cell leukemia homeobox interacting protein 1a
chr8_+_21192955 0.06 ENSDART00000129210
cry1ba
cryptochrome circadian clock 1ba
chr6_+_16342020 0.00 ENSDART00000114667
zgc:161969
zgc:161969

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0022602 ovarian follicle development(GO:0001541) ovulation cycle process(GO:0022602) ovulation cycle(GO:0042698)
0.3 1.0 GO:1905178 regulation of cardiac muscle tissue regeneration(GO:1905178)
0.2 1.7 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.5 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.1 0.4 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.1 0.8 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.1 0.6 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.1 0.5 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.8 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 1.3 GO:0061035 regulation of cartilage development(GO:0061035)
0.0 0.2 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.0 1.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 2.1 GO:0006096 glycolytic process(GO:0006096)
0.0 1.1 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.6 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.3 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.2 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.6 GO:0046890 regulation of lipid biosynthetic process(GO:0046890)
0.0 0.4 GO:0043409 negative regulation of MAPK cascade(GO:0043409)
0.0 0.2 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:1905097 regulation of guanyl-nucleotide exchange factor activity(GO:1905097) regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.8 GO:0006836 neurotransmitter transport(GO:0006836)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 1.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 1.1 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.9 GO:0014069 postsynaptic density(GO:0014069)
0.0 0.3 GO:0005902 microvillus(GO:0005902)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity(GO:0008489)
0.2 0.8 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.2 1.3 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.5 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 1.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.6 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 2.1 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.7 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.4 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 1.6 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.1 GO:0036459 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 0.9 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.8 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 1.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 1.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 1.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+