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Results for tfap2e

Z-value: 0.55

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Transcription factors associated with tfap2e

Gene Symbol Gene ID Gene Info
tfap2e
ENSDARG00000008861 transcription factor AP-2 epsilon

Activity profile of tfap2e motif

Sorted Z-values of tfap2e motif

Network of associatons between targets according to the STRING database.

First level regulatory network of tfap2e

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_+_24148599 1.70 ENSDART00000058629
acta1b
actin, alpha 1b, skeletal muscle
chr22_+_12327849 1.19 ENSDART00000178678
FO704572.1
ENSDARG00000106890
chr6_-_39315024 1.04 ENSDART00000012644
krt4
keratin 4
chr14_-_26406720 0.97 ENSDART00000078563
neurog1
neurogenin 1
chr19_-_23037220 0.89 ENSDART00000090669
pleca
plectin a
chr2_+_36634309 0.88 ENSDART00000169547
ENSDART00000098417
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr21_-_39013447 0.84 ENSDART00000114885
aldh3a2b
aldehyde dehydrogenase 3 family, member A2b
chr23_-_27721250 0.82 ENSDART00000059974
wnt10b
wingless-type MMTV integration site family, member 10b
chr9_+_33167554 0.79 ENSDART00000007630
nhlh2
nescient helix loop helix 2
KN150230v1_-_36595 0.76

chr5_-_37850885 0.67 ENSDART00000136428
ENSDART00000112487
chrne
cholinergic receptor, nicotinic, epsilon
chr7_-_72500748 0.65 ENSDART00000160523
CU929444.1
ENSDARG00000099109
chr19_-_35513216 0.65

chr8_+_54171992 0.64 ENSDART00000122692
CABZ01112317.1
ENSDARG00000086057
chr5_-_37851313 0.60 ENSDART00000136428
ENSDART00000112487
chrne
cholinergic receptor, nicotinic, epsilon
chr19_-_9553977 0.57 ENSDART00000045565
vamp1
vesicle-associated membrane protein 1
chr25_-_5039781 0.57

chr15_+_21399127 0.51 ENSDART00000154914
BX663520.1
ENSDARG00000097950
chr23_-_27721202 0.48 ENSDART00000059974
wnt10b
wingless-type MMTV integration site family, member 10b
chr19_+_17451381 0.45 ENSDART00000167602
spaca4l
sperm acrosome associated 4 like
chr17_+_25503946 0.44

chr3_+_29380133 0.44 ENSDART00000123619
rac2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr6_-_39315608 0.43 ENSDART00000012644
krt4
keratin 4
chr19_-_5453469 0.41 ENSDART00000105004
krt17
keratin 17
chr15_+_21399299 0.40 ENSDART00000154914
BX663520.1
ENSDARG00000097950
chr16_+_36952821 0.40 ENSDART00000160645
si:ch73-215d9.1
si:ch73-215d9.1
chr20_-_15181042 0.40 ENSDART00000175585
prrc2c
proline-rich coiled-coil 2C
chr25_+_35855292 0.40 ENSDART00000152801
ankrd27
ankyrin repeat domain 27 (VPS9 domain)
chr13_+_24148474 0.39 ENSDART00000058629
acta1b
actin, alpha 1b, skeletal muscle
chr19_+_47720261 0.38 ENSDART00000136647
ext1c
exostoses (multiple) 1c
chr19_-_27878747 0.35 ENSDART00000137638
si:ch73-25f10.6
si:ch73-25f10.6
chr10_-_5135388 0.33 ENSDART00000108587
sec31a
SEC31 homolog A, COPII coat complex component
chr3_-_54352640 0.30 ENSDART00000128041
dnmt1
DNA (cytosine-5-)-methyltransferase 1
chr24_+_33697332 0.29

chr5_-_62116975 0.28 ENSDART00000144469
adora2b
adenosine A2b receptor
chr11_+_31061296 0.28 ENSDART00000088093
sipa1l2
signal-induced proliferation-associated 1 like 2
chr4_-_2065017 0.28 ENSDART00000087835
ano6
anoctamin 6
chr23_-_5429419 0.27 ENSDART00000159105
CR936540.3
ENSDARG00000101435
chr20_-_20412830 0.26 ENSDART00000114779
ENSDARG00000079369
ENSDARG00000079369
chr7_-_15004167 0.23 ENSDART00000030009
ENSDARG00000023868
ENSDARG00000023868
chr19_-_27878556 0.23 ENSDART00000137638
si:ch73-25f10.6
si:ch73-25f10.6
chr3_-_56969897 0.23

chr10_+_5135537 0.23 ENSDART00000132627
ENSDART00000082295
zgc:113274
zgc:113274
chr8_-_7618945 0.20 ENSDART00000040672
mecp2
methyl CpG binding protein 2
chr3_+_25859153 0.20 ENSDART00000007398
gcat
glycine C-acetyltransferase
chr17_+_34238628 0.19 ENSDART00000014306
mpp5a
membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5)
chr24_-_21758244 0.19 ENSDART00000091252
spata13
spermatogenesis associated 13
chr11_-_11722452 0.18 ENSDART00000161293
CR848705.2
ENSDARG00000104692
chr15_+_21399228 0.18 ENSDART00000154914
BX663520.1
ENSDARG00000097950
chr2_+_36634251 0.18 ENSDART00000169547
ENSDART00000098417
pak2a
p21 protein (Cdc42/Rac)-activated kinase 2a
chr21_+_39918070 0.18 ENSDART00000135235
slc47a1
solute carrier family 47 (multidrug and toxin extrusion), member 1
chr24_+_42133471 0.17 ENSDART00000170514
top1mt
topoisomerase (DNA) I, mitochondrial
chr19_-_5452918 0.17 ENSDART00000105004
krt17
keratin 17
chr14_-_34265449 0.17 ENSDART00000144547
afap1l1a
actin filament associated protein 1-like 1a
chr2_-_15373241 0.16 ENSDART00000163858
si:dkey-10f21.4
si:dkey-10f21.4
chr9_+_33167471 0.15 ENSDART00000007630
nhlh2
nescient helix loop helix 2
chr16_-_7876036 0.14 ENSDART00000113483
trim71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr3_+_45345181 0.11

chr14_-_29498646 0.11

chr8_-_47156727 0.10

chr7_-_2308580 0.08 ENSDART00000098148
ENSDART00000173624
si:cabz01007802.1
si:cabz01007802.1
chr17_-_15141309 0.07 ENSDART00000103405
gch1
GTP cyclohydrolase 1
chr4_+_76581339 0.06 ENSDART00000174203
zgc:113921
zgc:113921
chr2_-_10724196 0.06

chr8_-_47156995 0.06

chr4_-_21745163 0.06 ENSDART00000139962
pawr
PRKC, apoptosis, WT1, regulator
chr13_+_24148390 0.06 ENSDART00000058629
acta1b
actin, alpha 1b, skeletal muscle
chr20_+_22780756 0.04

chr19_-_30923513 0.04 ENSDART00000088760
bag6l
BCL2-associated athanogene 6, like
chr2_-_22173254 0.04 ENSDART00000137538
rab2a
RAB2A, member RAS oncogene family
chr24_+_42133272 0.01 ENSDART00000170514
top1mt
topoisomerase (DNA) I, mitochondrial
chr10_+_16089472 0.01

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 1.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.1 0.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.1 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0010586 miRNA metabolic process(GO:0010586)
0.0 0.4 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.2 GO:0006566 threonine metabolic process(GO:0006566) threonine catabolic process(GO:0006567)
0.0 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.0 2.1 GO:0014904 myotube cell development(GO:0014904) skeletal muscle fiber development(GO:0048741)
0.0 0.3 GO:0035587 adenosine receptor signaling pathway(GO:0001973) purinergic receptor signaling pathway(GO:0035587) G-protein coupled purinergic receptor signaling pathway(GO:0035588)
0.0 0.4 GO:0007286 spermatid development(GO:0007286)
0.0 1.3 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.0 0.1 GO:0072672 neutrophil extravasation(GO:0072672) regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0 0.8 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.0 0.1 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.2 GO:0006265 DNA topological change(GO:0006265)
0.0 1.1 GO:0032147 activation of protein kinase activity(GO:0032147)
0.0 0.4 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0005869 dynactin complex(GO:0005869)
0.2 1.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 0.9 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0002102 podosome(GO:0002102)
0.0 0.2 GO:0000792 heterochromatin(GO:0000792)
0.0 0.6 GO:0005882 intermediate filament(GO:0005882)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0070888 E-box binding(GO:0070888)
0.1 1.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.4 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.8 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.9 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.2 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.0 0.3 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.0 1.3 GO:0005109 frizzled binding(GO:0005109)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0004675 transmembrane receptor protein serine/threonine kinase activity(GO:0004675)
0.0 0.1 GO:0042910 xenobiotic transporter activity(GO:0042910)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.3 NABA SECRETED FACTORS Genes encoding secreted soluble factors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 REACTOME ACETYLCHOLINE BINDING AND DOWNSTREAM EVENTS Genes involved in Acetylcholine Binding And Downstream Events
0.0 0.6 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events