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Results for tfcp2+tfcp2l1+ubp1
Z-value: 2.91
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Transcription factors associated with tfcp2+tfcp2l1+ubp1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| tfcp2 | dr10_dc_chr23_-_33753484_33753531 | -0.27 | 3.1e-01 | Click! |
| ubp1 | dr10_dc_chr19_+_43237078_43237198 | 0.26 | 3.4e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of tfcp2+tfcp2l1+ubp1
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_-_27516974 Show fit | 12.14 |
ENSDART00000151675
|
si:ch211-157c3.4 |
|
| chr10_+_39141022 Show fit | 6.56 |
ENSDART00000158245
|
si:ch73-1a9.3 |
|
| chr12_-_7572970 Show fit | 6.08 |
ENSDART00000158095
|
solute carrier family 16, member 9b |
|
| chr13_+_28364942 Show fit | 5.54 |
ENSDART00000025583
|
fibroblast growth factor 8a |
|
| chr22_+_21996941 Show fit | 5.49 |
ENSDART00000149586
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 1 |
|
| chr10_+_39140943 Show fit | 5.48 |
ENSDART00000158245
|
si:ch73-1a9.3 |
|
| chr21_+_25651712 Show fit | 5.48 |
ENSDART00000135123
|
si:dkey-17e16.17 |
|
| chr8_-_3253562 Show fit | 5.40 |
ENSDART00000035965
|
fucosyltransferase 9b |
|
| chr10_-_15090647 Show fit | 5.19 |
ENSDART00000038401
ENSDART00000155674 |
si:ch211-95j8.2 |
|
| chr24_+_38783264 Show fit | 4.94 |
ENSDART00000154214
|
si:ch73-70c5.1 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 10.3 | GO:0043587 | tongue development(GO:0043586) tongue morphogenesis(GO:0043587) taste bud development(GO:0061193) taste bud morphogenesis(GO:0061194) taste bud formation(GO:0061195) |
| 0.9 | 10.0 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 0.2 | 8.8 | GO:0007189 | adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189) |
| 0.1 | 6.1 | GO:0015718 | monocarboxylic acid transport(GO:0015718) |
| 0.7 | 5.8 | GO:0060142 | regulation of syncytium formation by plasma membrane fusion(GO:0060142) |
| 0.5 | 5.4 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
| 0.0 | 5.3 | GO:0008154 | actin polymerization or depolymerization(GO:0008154) |
| 0.4 | 4.4 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 4.4 | GO:0031101 | fin regeneration(GO:0031101) |
| 0.2 | 4.3 | GO:0001649 | osteoblast differentiation(GO:0001649) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 16.1 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.0 | 15.0 | GO:0000785 | chromatin(GO:0000785) |
| 0.2 | 11.0 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.1 | 10.3 | GO:0005764 | lysosome(GO:0005764) |
| 0.1 | 10.1 | GO:0030424 | axon(GO:0030424) |
| 0.1 | 4.7 | GO:0030175 | filopodium(GO:0030175) |
| 0.1 | 3.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 3.6 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.5 | 2.3 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.0 | 2.2 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 15.6 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 2.1 | 10.3 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.0 | 10.3 | GO:0008270 | zinc ion binding(GO:0008270) |
| 1.1 | 10.0 | GO:0031826 | type 2A serotonin receptor binding(GO:0031826) |
| 0.1 | 7.8 | GO:0004930 | G-protein coupled receptor activity(GO:0004930) |
| 0.2 | 6.1 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.0 | 6.0 | GO:0005085 | guanyl-nucleotide exchange factor activity(GO:0005085) |
| 0.0 | 5.7 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
| 1.8 | 5.4 | GO:0004360 | glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360) L-glutamine aminotransferase activity(GO:0070548) |
| 0.9 | 4.7 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.5 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.1 | 3.1 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.0 | 2.4 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 1.7 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.0 | 1.1 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.2 | PID IL5 PATHWAY | IL5-mediated signaling events |
| 0.0 | 0.2 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 0.1 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.4 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.3 | 3.1 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 0.1 | 2.8 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.4 | 2.6 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 2.4 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 2.3 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.1 | 2.1 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.1 | 2.1 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 1.7 | REACTOME G1 PHASE | Genes involved in G1 Phase |
| 0.0 | 1.7 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |