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Results for tfe3a

Z-value: 0.84

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Transcription factors associated with tfe3a

Gene Symbol Gene ID Gene Info
ENSDARG00000098903 transcription factor binding to IGHM enhancer 3a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
tfe3adr10_dc_chr8_+_7739964_7740002-0.233.9e-01Click!

Activity profile of tfe3a motif

Sorted Z-values of tfe3a motif

Network of associatons between targets according to the STRING database.

First level regulatory network of tfe3a

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_+_32670368 1.62 ENSDART00000142449
cathepsin Ba
chr12_-_2834771 1.39 ENSDART00000114854
ENSDART00000163759
zinc finger, DHHC-type containing 16b
chr13_+_50990946 1.32

chr15_-_17163526 1.30 ENSDART00000101724
v-mos Moloney murine sarcoma viral oncogene homolog
chr12_-_2834814 1.23 ENSDART00000114854
ENSDART00000163759
zinc finger, DHHC-type containing 16b
chr7_+_51520610 1.12 ENSDART00000174201
solute carrier family 38, member 7
chr19_+_15536640 1.06 ENSDART00000098970
lin-28 homolog A (C. elegans)
chr9_-_8318363 1.04 ENSDART00000139867
si:ch211-145c1.1
chr21_+_38024999 0.99 ENSDART00000142106
Kruppel-like factor 8
chr2_-_57339717 0.96 ENSDART00000150034
protein inhibitor of activated STAT, 4b
chr6_+_135002 0.96 ENSDART00000097468
zinc finger, GATA-like protein 1
KN150699v1_-_15078 0.94 ENSDART00000159861
ENSDARG00000098739
chr23_-_31986679 0.92 ENSDART00000085054
mitochondrial fission regulator 2
chr23_-_22596648 0.92 ENSDART00000079019
splA/ryanodine receptor domain and SOCS box containing 1
chr17_-_25313024 0.91 ENSDART00000082324
zona pellucida protein C
chr19_-_42933592 0.90 ENSDART00000007642
zgc:110239
chr10_-_44441390 0.89 ENSDART00000160231
strawberry notch homolog 1 (Drosophila)
chr14_+_30202682 0.88 ENSDART00000145336
hairy-related 5
chr13_-_17991273 0.87 ENSDART00000128748
family with sequence similarity 21, member C
chr21_+_4375508 0.87 ENSDART00000043431
nucleoporin 188
chr6_+_11162062 0.85 ENSDART00000151548
SUMO1/sentrin/SMT3 specific peptidase 2
chr15_+_1238560 0.80 ENSDART00000167760
ENSDART00000163827
major facilitator superfamily domain containing 1
chr16_-_4350251 0.80

chr3_-_15325357 0.79 ENSDART00000139575
spinster homolog 1 (Drosophila)
chr15_+_43682831 0.79 ENSDART00000168589
cathepsin C
chr3_-_18655432 0.77 ENSDART00000034489
methionine sulfoxide reductase B1a
chr25_+_22222388 0.76 ENSDART00000154376
cytochrome P450, family 11, subfamily A, polypeptide 1
chr22_-_22337268 0.75

chr8_-_52952141 0.74 ENSDART00000168185
nuclear receptor subfamily 6, group A, member 1a
chr13_+_46487890 0.74

KN150563v1_-_10770 0.71

chr9_-_56692366 0.71

chr3_+_39426628 0.71 ENSDART00000137999
aldolase a, fructose-bisphosphate, a
chr7_+_55217087 0.69 ENSDART00000149915
chromatin licensing and DNA replication factor 1
chr7_+_40866623 0.67 ENSDART00000052274
poly-U binding splicing factor b
chr3_+_39426379 0.67 ENSDART00000020741
aldolase a, fructose-bisphosphate, a
chr20_-_25732204 0.67 ENSDART00000048164
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr22_+_15317622 0.66 ENSDART00000045682
ribosomal RNA processing 36
KN150421v1_+_14181 0.66

chr3_-_32231069 0.66 ENSDART00000035545
protein arginine methyltransferase 1
chr24_-_30929990 0.66

chr9_+_4382041 0.65

chr4_-_7867294 0.65 ENSDART00000167943
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr7_+_45747395 0.65 ENSDART00000163991
cyclin E1
chr23_+_32102030 0.65 ENSDART00000145501
TPX2, microtubule-associated, homolog (Xenopus laevis)
chr20_-_52002087 0.65 ENSDART00000041476
melanoma inhibitory activity family, member 3
KN150563v1_-_10915 0.65

chr24_-_30930178 0.65

chr15_-_33669717 0.64 ENSDART00000161151
StAR-related lipid transfer (START) domain containing 13b
chr10_-_35205636 0.63 ENSDART00000131291
receptor-interacting serine-threonine kinase 4
chr16_+_24045707 0.63 ENSDART00000058965
apolipoprotein Eb
chr1_+_41644371 0.62 ENSDART00000143871
catenin (cadherin-associated protein), alpha 2
chr10_-_44441197 0.62 ENSDART00000160231
strawberry notch homolog 1 (Drosophila)
chr5_-_56539892 0.62

chr16_+_4350448 0.61

chr16_+_43468861 0.61

chr12_+_30389706 0.60

chr17_+_49995001 0.60 ENSDART00000113644
vacuolar protein sorting 39 homolog (S. cerevisiae)
chr17_+_23291331 0.59 ENSDART00000128073
protein phosphatase 1, regulatory subunit 3Ca
chr19_-_808376 0.58 ENSDART00000140119
glycosylated lysosomal membrane protein
chr23_+_38313746 0.58 ENSDART00000129593
zinc finger protein 217
chr4_+_17666992 0.57 ENSDART00000066999
coiled-coil domain containing 53
chr15_-_14102102 0.57 ENSDART00000139068
zgc:114130
chr7_+_1443102 0.57 ENSDART00000172830
SPT16 homolog, facilitates chromatin remodeling subunit
chr15_-_33669618 0.57 ENSDART00000161151
StAR-related lipid transfer (START) domain containing 13b
chr10_-_24754849 0.56 ENSDART00000148582
sphingomyelin phosphodiesterase 1, acid lysosomal
chr16_+_33209956 0.56 ENSDART00000101943
Ras-related GTP binding Ca
chr16_+_20690902 0.56 ENSDART00000078984
carboxypeptidase, vitellogenic-like
chr23_+_26153043 0.56 ENSDART00000054013
ATPase, H+ transporting, lysosomal accessory protein 1b
chr1_-_39141284 0.55 ENSDART00000053763
dCMP deaminase
chr14_-_46608307 0.55 ENSDART00000074038
SCY1-like, kinase-like 1
chr8_-_44247277 0.55

chr18_+_14725283 0.54 ENSDART00000146128
URI1, prefoldin-like chaperone
chr21_+_7737161 0.54

chr18_-_16927749 0.54 ENSDART00000100105
ENSDART00000163400
SWAP switching B-cell complex 70b subunit 70b
chr20_+_26005068 0.53 ENSDART00000016864
solute carrier family 35, member F6
chr15_-_25025251 0.53 ENSDART00000109990
abhydrolase domain containing 15a
chr17_+_17745119 0.53 ENSDART00000138189
ENSDART00000105013
alkB homolog 1, histone H2A dioxygenase
chr23_+_10870124 0.52 ENSDART00000035693
protein phosphatase 4, regulatory subunit 2a
chr20_+_26495546 0.51 ENSDART00000036942
zinc finger and BTB domain containing 2b
chr3_+_4123775 0.51 ENSDART00000056035
ENSDARG00000038398
chr11_-_25019298 0.51 ENSDART00000130477
ENSDART00000079578
snail family zinc finger 1a
chr16_-_5243402 0.50 ENSDART00000131876
ttk protein kinase
chr21_-_3548863 0.50 ENSDART00000086492
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr7_+_27184121 0.50 ENSDART00000148417
cytochrome P450, family 2, subfamily R, polypeptide 1
chr15_+_35081979 0.50 ENSDART00000131182
zgc:66024
chr20_-_51287350 0.50 ENSDART00000023488
ATPase, H+ transporting, lysosomal V1 subunit D
chr18_+_27095398 0.50 ENSDART00000125326
ENSDART00000098334
protein phosphatase 1, regulatory subunit 15B
chr14_+_21373857 0.50 ENSDART00000079649
ENSDART00000165795
NADH dehydrogenase (ubiquinone) Fe-S protein 8b
chr25_-_35819452 0.49 ENSDART00000064400
si:ch211-113a14.24
chr15_+_1569674 0.49 ENSDART00000130413
structural maintenance of chromosomes 4
chr14_-_17270022 0.49 ENSDART00000123145
ring finger protein 4
chr11_-_14044356 0.49 ENSDART00000085158
transmembrane protein 259
chr5_+_50266345 0.48 ENSDART00000092938
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein a
chr3_-_15325178 0.48 ENSDART00000139575
spinster homolog 1 (Drosophila)
chr3_-_32231192 0.48 ENSDART00000012630
protein arginine methyltransferase 1
chr5_-_54091790 0.48 ENSDART00000150070
cyclin B1
chr8_-_52952226 0.47 ENSDART00000168185
nuclear receptor subfamily 6, group A, member 1a
chr25_+_2968769 0.47

chr3_+_14314116 0.47 ENSDART00000170927
calponin 1, basic, smooth muscle, b
chr21_+_10692781 0.47

chr3_+_31530419 0.47 ENSDART00000113441
myosin, light chain kinase 5
chr13_+_25374720 0.46 ENSDART00000140634
inositol polyphosphate-5-phosphatase F
chr10_+_32107014 0.46 ENSDART00000137373
si:ch211-266i6.3
chr25_-_19510499 0.46 ENSDART00000166824
G-2 and S-phase expressed 1
chr13_-_2296041 0.46 ENSDART00000126697
glutamate-cysteine ligase, catalytic subunit
chr17_+_24790812 0.46 ENSDART00000082251
speedy/RINGO cell cycle regulator family member A
chr2_+_25281122 0.46 ENSDART00000025962
glycogenin 1a
chr17_+_30826890 0.46 ENSDART00000149600
tripeptidyl peptidase I
chr5_-_23296575 0.45 ENSDART00000134184
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
chr25_-_24105014 0.45 ENSDART00000048507
UEV and lactate/malate dehyrogenase domains
chr9_-_56692281 0.45

chr13_-_35924447 0.44 ENSDART00000134955
legumain
chr10_+_5267937 0.44 ENSDART00000114491
receptor tyrosine kinase-like orphan receptor 2
chr11_-_38856849 0.44 ENSDART00000113185
adaptor-related protein complex 5, beta 1 subunit
chr7_-_41532268 0.44 ENSDART00000016105
ENSDART00000138800
vacuolar protein sorting 35 homolog (S. cerevisiae)
chr16_-_31664756 0.44 ENSDART00000176939
PHD finger protein 20-like 1
chr3_-_42949449 0.44 ENSDART00000161127
axin 1
chr3_+_42217187 0.44 ENSDART00000168228
transmembrane protein 184a
chr24_-_20946041 0.44 ENSDART00000140786
queuine tRNA-ribosyltransferase domain containing 1
chr13_-_31557441 0.43 ENSDART00000085989
TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)
chr14_-_35513309 0.43 ENSDART00000173343
platelet derived growth factor c
chr4_-_765957 0.43 ENSDART00000128743
transmembrane protein 214
chr23_+_34021303 0.43 ENSDART00000136104
si:ch211-148l7.4
chr19_-_2148053 0.42 ENSDART00000020497
sorting nexin 13
chr7_-_19713757 0.42

chr5_-_9036049 0.42 ENSDART00000160079
cyclin G associated kinase
chr18_-_1745485 0.42

chr16_+_24045774 0.42 ENSDART00000133484
apolipoprotein Eb
chr6_+_54672873 0.42 ENSDART00000074602
sphingomyelin phosphodiesterase 2b, neutral membrane (neutral sphingomyelinase)
chr3_-_22240424 0.42

chr24_-_30929960 0.42

chr21_+_38025480 0.42 ENSDART00000142106
Kruppel-like factor 8
chr24_+_40321763 0.42

chr17_+_7377230 0.41 ENSDART00000157123
SNF2 histone linker PHD RING helicase
chr14_+_15982295 0.41 ENSDART00000106593
pre-mRNA processing factor 19
chr13_-_4863766 0.41 ENSDART00000159679
nucleolar and coiled-body phosphoprotein 1
chr23_+_20586745 0.41 ENSDART00000157522
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
chr3_+_42217236 0.41 ENSDART00000168228
transmembrane protein 184a
chr10_-_35205597 0.41 ENSDART00000131291
receptor-interacting serine-threonine kinase 4
chr11_+_38858311 0.41 ENSDART00000155746
cell division cycle 42
chr18_-_26131468 0.41

chr4_+_18427325 0.41

chr7_+_41532360 0.41 ENSDART00000174333
origin recognition complex, subunit 6
chr14_-_47387481 0.40 ENSDART00000031498
cyclin A2
chr7_+_25554355 0.40 ENSDART00000149835
myotubularin 1
chr16_+_19223683 0.40 ENSDART00000115263
ENSDART00000114954
Rap guanine nucleotide exchange factor (GEF) 5b
chr23_-_2957262 0.40 ENSDART00000165955
zinc fingers and homeoboxes 3
chr6_+_131451 0.40 ENSDART00000166361
ferredoxin 1-like
chr20_-_223222 0.40 ENSDART00000104790
zinc finger protein 292b
chr2_-_23330863 0.39

chr23_-_19125310 0.39 ENSDART00000140866
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr12_+_33219727 0.39 ENSDART00000021491
casein kinase 1, delta b
chr11_+_44678488 0.39 ENSDART00000163408
si:dkey-93h22.8
chr15_-_33669589 0.39 ENSDART00000161151
StAR-related lipid transfer (START) domain containing 13b
chr21_-_19883182 0.39 ENSDART00000065670
protein phosphatase 1, regulatory subunit 3B
chr1_-_28257339 0.39 ENSDART00000148331
gem (nuclear organelle) associated protein 8
chr23_-_18105560 0.39

chr9_+_42355513 0.39 ENSDART00000142888
leucine rich repeat containing 3
chr24_+_35296642 0.38 ENSDART00000172652
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr14_+_20927461 0.38 ENSDART00000160576
si:ch211-175m2.4
chr14_+_5528229 0.38 ENSDART00000140260
ancient ubiquitous protein 1
chr8_-_47339228 0.38 ENSDART00000060853
peroxisomal biogenesis factor 10
chr21_+_6289363 0.38 ENSDART00000138600
si:ch211-225g23.1
chr8_-_29842489 0.37 ENSDART00000149297
solute carrier family 20 (phosphate transporter), member 2
chr17_-_44326992 0.37 ENSDART00000148786
exocyst complex component 5
chr8_-_16689736 0.37 ENSDART00000049676
DEP domain containing 1a
chr17_-_20267580 0.37 ENSDART00000078703
adducin 3 (gamma) b
chr5_-_60664244 0.37 ENSDART00000136553
si:ch211-209a2.2
chr3_-_15992035 0.37 ENSDART00000016616
ADP-ribosylation factor-like 5C
chr4_+_5332964 0.37 ENSDART00000123375
zgc:113263
chr13_-_29571309 0.37 ENSDART00000139773
ENSDARG00000093614
chr24_+_35296732 0.37 ENSDART00000172652
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr1_-_7882397 0.36 ENSDART00000114613
pentatricopeptide repeat domain 1
chr23_+_26152909 0.36 ENSDART00000129617
ATPase, H+ transporting, lysosomal accessory protein 1b
chr19_+_365865 0.36 ENSDART00000093383
vacuolar protein sorting 72 homolog (S. cerevisiae)
chr6_+_135255 0.36 ENSDART00000097468
zinc finger, GATA-like protein 1
chr17_+_24791024 0.36 ENSDART00000130871
speedy/RINGO cell cycle regulator family member A
chr8_-_16614882 0.36 ENSDART00000135319
oxysterol binding protein-like 9
chr10_-_15921335 0.36 ENSDART00000136789
tight junction protein 2a (zona occludens 2)
chr4_-_11126782 0.36 ENSDART00000150419
ENSDARG00000096039
chr20_-_25732091 0.36 ENSDART00000048164
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
chr17_+_25313170 0.36 ENSDART00000157309
transmembrane protein 54a
chr13_+_25374865 0.35 ENSDART00000140634
inositol polyphosphate-5-phosphatase F
chr13_-_2296283 0.35 ENSDART00000017148
glutamate-cysteine ligase, catalytic subunit
chr8_-_20213672 0.35 ENSDART00000136911
alkaline ceramidase 1
chr15_-_16241412 0.35 ENSDART00000156352
si:ch211-259g3.4
chr14_-_21779536 0.35

chr18_+_16144493 0.35 ENSDART00000080423
cathepsin D
chr19_-_27239547 0.35 ENSDART00000149132
neuraminidase 1
chr5_-_32290516 0.35 ENSDART00000007512
polymerase (DNA directed), epsilon 3 (p17 subunit)
chr24_-_36382704 0.35 ENSDART00000154858
si:ch211-40k21.5
chr3_-_25290808 0.35 ENSDART00000154200
bromodomain PHD finger transcription factor
chr7_+_28905795 0.35 ENSDART00000146655
APH1B gamma secretase subunit
chr15_+_43682994 0.35 ENSDART00000168589
cathepsin C
chr22_+_21491685 0.35 ENSDART00000136374
mesoderm induction early response 1, family member 2
chr16_+_14326410 0.34 ENSDART00000113093
glucosidase, beta, acid
chr20_-_16949608 0.34 ENSDART00000027582
breast cancer metastasis-suppressor 1-like b
chr24_-_42132495 0.34

chr24_-_30930283 0.34

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0071831 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830) intermediate-density lipoprotein particle clearance(GO:0071831)
0.4 1.1 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.3 1.7 GO:1901994 meiotic cell cycle phase transition(GO:0044771) metaphase/anaphase transition of meiotic cell cycle(GO:0044785) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902102) negative regulation of metaphase/anaphase transition of meiotic cell cycle(GO:1902103) regulation of meiotic chromosome separation(GO:1905132) negative regulation of meiotic chromosome separation(GO:1905133)
0.3 1.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.3 0.8 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 1.7 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.2 0.9 GO:0008057 eye pigment granule organization(GO:0008057)
0.2 0.6 GO:1902635 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process(GO:1902633) 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process(GO:1902635)
0.2 0.9 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.2 0.5 GO:0045687 positive regulation of glial cell differentiation(GO:0045687) positive regulation of oligodendrocyte differentiation(GO:0048714)
0.2 0.5 GO:0035513 oxidative RNA demethylation(GO:0035513) oxidative single-stranded DNA demethylation(GO:0035552)
0.2 0.7 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.2 0.5 GO:0071305 vitamin D3 metabolic process(GO:0070640) cellular response to vitamin D(GO:0071305)
0.2 0.6 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.2 0.6 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.4 GO:0030279 negative regulation of ossification(GO:0030279)
0.1 0.8 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 1.0 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.6 GO:0006226 dUMP biosynthetic process(GO:0006226) dUMP metabolic process(GO:0046078)
0.1 0.8 GO:1902423 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) regulation of mitotic attachment of spindle microtubules to kinetochore(GO:1902423) positive regulation of attachment of mitotic spindle microtubules to kinetochore(GO:1902425) RNA localization to chromatin(GO:1990280)
0.1 0.7 GO:0032516 positive regulation of phosphatase activity(GO:0010922) positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 1.4 GO:0021683 cerebellar granular layer development(GO:0021681) cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.9 GO:1904031 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737) positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 0.3 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.1 0.3 GO:0010312 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
0.1 0.4 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.3 GO:0043476 pigment accumulation(GO:0043476)
0.1 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.3 GO:0010084 specification of organ axis polarity(GO:0010084)
0.1 0.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.1 0.3 GO:1903232 melanosome assembly(GO:1903232)
0.1 0.3 GO:0005997 xylulose metabolic process(GO:0005997)
0.1 0.4 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887) coenzyme transport(GO:0051182)
0.1 0.6 GO:1905066 regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 1.3 GO:0090398 cellular senescence(GO:0090398)
0.1 0.4 GO:0072319 clathrin coat disassembly(GO:0072318) vesicle uncoating(GO:0072319)
0.1 0.3 GO:0043393 regulation of protein binding(GO:0043393)
0.1 0.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.1 0.7 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.2 GO:0031048 chromatin silencing by small RNA(GO:0031048)
0.1 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.4 GO:0003222 ventricular trabecula myocardium morphogenesis(GO:0003222)
0.1 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.4 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.1 0.9 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.5 GO:1904292 regulation of ERAD pathway(GO:1904292)
0.1 0.1 GO:2000009 negative regulation of cellular protein localization(GO:1903828) regulation of protein localization to cell surface(GO:2000008) negative regulation of protein localization to cell surface(GO:2000009)
0.1 0.2 GO:0035523 protein K29-linked deubiquitination(GO:0035523) protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947) protein K33-linked deubiquitination(GO:1990168)
0.1 0.6 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 0.3 GO:0034505 tooth mineralization(GO:0034505)
0.1 0.3 GO:0018872 arsonoacetate metabolic process(GO:0018872)
0.1 0.2 GO:0042766 nucleosome mobilization(GO:0042766)
0.1 1.5 GO:0000266 mitochondrial fission(GO:0000266)
0.1 0.8 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.2 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 0.6 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 0.2 GO:0061011 meiotic DNA double-strand break processing(GO:0000706) hepatic duct development(GO:0061011)
0.1 0.2 GO:0010662 negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.1 0.2 GO:0046546 development of primary male sexual characteristics(GO:0046546) male sex differentiation(GO:0046661)
0.1 0.2 GO:2001271 negative regulation of execution phase of apoptosis(GO:1900118) regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270) negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.2 GO:0009092 homoserine metabolic process(GO:0009092) cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) transsulfuration(GO:0019346)
0.1 1.7 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.1 0.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.4 GO:0045109 intermediate filament organization(GO:0045109) negative regulation of autophagosome assembly(GO:1902902)
0.1 0.2 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.1 0.2 GO:0015882 L-ascorbic acid transport(GO:0015882)
0.1 0.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 1.8 GO:0048599 oocyte development(GO:0048599)
0.1 0.9 GO:0060046 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036) egg coat formation(GO:0035803) regulation of acrosome reaction(GO:0060046) positive regulation of acrosome reaction(GO:2000344)
0.1 0.5 GO:0032387 negative regulation of intracellular transport(GO:0032387)
0.1 2.7 GO:0018345 protein palmitoylation(GO:0018345)
0.1 0.3 GO:0034341 monocyte chemotaxis(GO:0002548) response to interferon-gamma(GO:0034341) cellular response to interferon-gamma(GO:0071346)
0.1 0.3 GO:0046386 deoxyribonucleotide catabolic process(GO:0009264) deoxyribose phosphate catabolic process(GO:0046386)
0.1 1.2 GO:0016925 protein sumoylation(GO:0016925)
0.1 0.2 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.2 GO:0097101 blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.5 GO:0090382 phagosome maturation(GO:0090382)
0.1 0.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.7 GO:0006684 sphingomyelin metabolic process(GO:0006684)
0.0 0.4 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.4 GO:1903292 protein localization to Golgi membrane(GO:1903292)
0.0 0.6 GO:0035459 cargo loading into vesicle(GO:0035459)
0.0 0.5 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.2 GO:0051029 rRNA export from nucleus(GO:0006407) rRNA transport(GO:0051029)
0.0 0.2 GO:0031174 lifelong otolith mineralization(GO:0031174)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.6 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.6 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 0.6 GO:0010962 regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.0 0.8 GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling(GO:0014068)
0.0 0.3 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.3 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.3 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 0.1 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.6 GO:0006000 fructose metabolic process(GO:0006000) fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.2 GO:0071869 response to monoamine(GO:0071867) response to catecholamine(GO:0071869) response to epinephrine(GO:0071871)
0.0 0.1 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.6 GO:0090224 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 1.1 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.0 0.5 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.3 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.6 GO:0048922 posterior lateral line neuromast deposition(GO:0048922)
0.0 0.1 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.0 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.2 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.4 GO:1904356 regulation of telomere maintenance via telomere lengthening(GO:1904356)
0.0 0.5 GO:0001966 thigmotaxis(GO:0001966) fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0040014 regulation of multicellular organism growth(GO:0040014)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.3 GO:0051928 positive regulation of calcium ion transport(GO:0051928)
0.0 0.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 0.1 GO:0008542 associative learning(GO:0008306) visual learning(GO:0008542) mammillary axonal complex development(GO:0061373) mammillothalamic axonal tract development(GO:0061374) corpora quadrigemina development(GO:0061378) inferior colliculus development(GO:0061379) cell migration in diencephalon(GO:0061381)
0.0 0.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.2 GO:0019079 viral genome replication(GO:0019079) negative stranded viral RNA replication(GO:0039689) viral RNA genome replication(GO:0039694) RNA replication(GO:0039703) multi-organism biosynthetic process(GO:0044034)
0.0 2.0 GO:0031101 fin regeneration(GO:0031101)
0.0 0.3 GO:0044872 lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872)
0.0 0.1 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.3 GO:0045471 response to ethanol(GO:0045471)
0.0 1.2 GO:1902593 protein import into nucleus(GO:0006606) protein targeting to nucleus(GO:0044744) single-organism nuclear import(GO:1902593)
0.0 0.1 GO:0021588 cerebellum formation(GO:0021588)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.3 GO:0031952 regulation of protein autophosphorylation(GO:0031952)
0.0 0.3 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.3 GO:0051127 positive regulation of actin nucleation(GO:0051127) positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 1.0 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 0.5 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.1 GO:0071938 vitamin A transport(GO:0071938) vitamin A import(GO:0071939)
0.0 0.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0009409 response to cold(GO:0009409)
0.0 0.7 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.4 GO:0045494 Golgi to plasma membrane transport(GO:0006893) photoreceptor cell maintenance(GO:0045494)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.1 GO:0098927 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.0 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.8 GO:0016575 histone deacetylation(GO:0016575)
0.0 0.3 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.3 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.2 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.1 GO:0044528 regulation of mitochondrial mRNA stability(GO:0044528)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 1.0 GO:0045765 regulation of angiogenesis(GO:0045765)
0.0 0.7 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.3 GO:0003323 type B pancreatic cell development(GO:0003323)
0.0 0.2 GO:0042113 B cell activation(GO:0042113)
0.0 0.1 GO:0007135 meiosis II(GO:0007135) meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.2 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.1 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.3 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:2000779 regulation of double-strand break repair(GO:2000779)
0.0 0.5 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of chemotaxis(GO:0050922) negative regulation of axon guidance(GO:1902668)
0.0 0.1 GO:0032509 endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0 0.2 GO:1903321 negative regulation of protein ubiquitination(GO:0031397) negative regulation of protein modification by small protein conjugation or removal(GO:1903321)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.3 0.9 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 1.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.2 0.8 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.2 1.0 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.4 GO:0097124 cyclin A2-CDK2 complex(GO:0097124)
0.1 0.8 GO:0000803 sex chromosome(GO:0000803) inactive sex chromosome(GO:0098577)
0.1 0.9 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 0.4 GO:0033263 CORVET complex(GO:0033263)
0.1 0.3 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.6 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 0.5 GO:0008623 CHRAC(GO:0008623)
0.1 1.9 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 0.3 GO:0031085 BLOC-3 complex(GO:0031085)
0.1 0.6 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.6 GO:0035101 FACT complex(GO:0035101)
0.1 1.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.6 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.3 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.2 GO:0044326 dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)
0.1 0.4 GO:0032797 SMN complex(GO:0032797)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.5 GO:0071986 Ragulator complex(GO:0071986)
0.1 0.4 GO:0070187 telosome(GO:0070187)
0.1 0.4 GO:0071012 U2-type catalytic step 1 spliceosome(GO:0071006) catalytic step 1 spliceosome(GO:0071012)
0.0 0.3 GO:0071546 pi-body(GO:0071546)
0.0 0.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0030666 endocytic vesicle membrane(GO:0030666) phagocytic vesicle membrane(GO:0030670)
0.0 0.8 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.9 GO:0030686 90S preribosome(GO:0030686)
0.0 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.0 1.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 5.9 GO:0005764 lysosome(GO:0005764)
0.0 0.4 GO:0044545 NSL complex(GO:0044545)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.5 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.4 GO:0005876 spindle microtubule(GO:0005876)
0.0 1.3 GO:0008287 protein serine/threonine phosphatase complex(GO:0008287) phosphatase complex(GO:1903293)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0071005 U2-type precatalytic spliceosome(GO:0071005)
0.0 0.3 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.8 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.4 GO:0000786 nucleosome(GO:0000786)
0.0 0.7 GO:0000776 kinetochore(GO:0000776)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.4 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.4 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.4 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.4 1.3 GO:0033745 L-methionine-(R)-S-oxide reductase activity(GO:0033745)
0.4 1.1 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.3 0.8 GO:0016595 glutamate-cysteine ligase activity(GO:0004357) glutamate binding(GO:0016595)
0.3 0.8 GO:0016713 cholesterol monooxygenase (side-chain-cleaving) activity(GO:0008386) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.2 1.1 GO:0052834 inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.2 0.7 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.2 0.6 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 1.0 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
0.2 0.9 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 0.5 GO:0035514 DNA demethylase activity(GO:0035514) oxidative RNA demethylase activity(GO:0035515)
0.2 0.8 GO:0003948 N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity(GO:0003948)
0.2 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.8 GO:0034338 short-chain carboxylesterase activity(GO:0034338)
0.1 0.8 GO:0001097 TFIIH-class transcription factor binding(GO:0001097) poly(C) RNA binding(GO:0017130)
0.1 0.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.8 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 0.3 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 0.3 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 1.3 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 0.9 GO:0035804 structural constituent of egg coat(GO:0035804)
0.1 1.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 1.3 GO:2001069 glycogen binding(GO:2001069)
0.1 0.4 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 0.4 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.1 0.3 GO:0034584 piRNA binding(GO:0034584)
0.1 0.3 GO:0043531 ADP binding(GO:0043531)
0.1 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.4 GO:0004067 asparaginase activity(GO:0004067)
0.1 0.9 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 0.3 GO:0030792 arsenite methyltransferase activity(GO:0030791) methylarsonite methyltransferase activity(GO:0030792)
0.1 2.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.3 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.1 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.3 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.0 0.3 GO:0004530 deoxyribonuclease I activity(GO:0004530) 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.2 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.0 0.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.8 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 3.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.2 GO:0004936 alpha-adrenergic receptor activity(GO:0004936) alpha1-adrenergic receptor activity(GO:0004937)
0.0 1.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.1 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups(GO:0016725)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0015377 cation:chloride symporter activity(GO:0015377) potassium:chloride symporter activity(GO:0015379)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0072542 phosphatase activator activity(GO:0019211) protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.2 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 0.2 GO:0035173 histone kinase activity(GO:0035173) steroid hormone receptor binding(GO:0035258)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.6 GO:0019239 deaminase activity(GO:0019239)
0.0 0.3 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 2.2 GO:0042803 protein homodimerization activity(GO:0042803)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.5 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 0.2 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters(GO:0016894)
0.0 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0051117 ATPase binding(GO:0051117)
0.0 0.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.6 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.7 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 1.1 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0 0.2 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.9 GO:0003724 RNA helicase activity(GO:0003724)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.3 GO:0071949 FAD binding(GO:0071949)
0.0 0.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.4 GO:0000049 tRNA binding(GO:0000049)
0.0 0.1 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.6 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0017075 syntaxin-1 binding(GO:0017075)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 2.4 PID MYC PATHWAY C-MYC pathway
0.1 0.5 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.0 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.5 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.3 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 1.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.3 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.2 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 PID INSULIN PATHWAY Insulin Pathway
0.0 1.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.1 0.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 1.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.0 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.3 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.7 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 1.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.7 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.7 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.1 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.1 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening