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Results for thraa+thrab

Z-value: 1.59

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Transcription factors associated with thraa+thrab

Gene Symbol Gene ID Gene Info
thraa
ENSDARG00000000151 thyroid hormone receptor alpha a
thrab
ENSDARG00000052654 thyroid hormone receptor alpha b

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
thrabdr10_dc_chr12_-_21918058_219181090.712.0e-03Click!
thraadr10_dc_chr3_-_34623996_34624121-0.543.0e-02Click!

Activity profile of thraa+thrab motif

Sorted Z-values of thraa+thrab motif

Network of associatons between targets according to the STRING database.

First level regulatory network of thraa+thrab

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr7_-_41347831 4.25 ENSDART00000174304
plxdc2
plexin domain containing 2
chr6_-_13654186 4.03 ENSDART00000150102
ENSDART00000041269
cryba2a
crystallin, beta A2a
chr15_+_37204488 3.48 ENSDART00000157762
aplp1
amyloid beta (A4) precursor-like protein 1
chr12_-_3098744 3.34 ENSDART00000015092
col1a1b
collagen, type I, alpha 1b
chr18_-_15404998 3.32 ENSDART00000031752
rfx4
regulatory factor X, 4
chr7_+_19765237 3.31 ENSDART00000100808
bcl6b
B-cell CLL/lymphoma 6, member B
chr21_+_39140701 3.22 ENSDART00000075992
cryba1b
crystallin, beta A1b
chr7_-_16776026 3.18 ENSDART00000022441
dbx1a
developing brain homeobox 1a
chr23_-_26150495 3.07 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr23_+_44817648 3.05 ENSDART00000143688
dlg4b
discs, large homolog 4b (Drosophila)
chr24_-_39722595 3.04 ENSDART00000066506
cox6b1
cytochrome c oxidase subunit VIb polypeptide 1
chr10_+_6316944 3.03 ENSDART00000162428
tpm2
tropomyosin 2 (beta)
chr2_-_28446615 2.91 ENSDART00000179495
cdh6
cadherin 6
chr19_-_24859287 2.89 ENSDART00000163763
thbs3b
thrombospondin 3b
chr9_-_22461196 2.86 ENSDART00000135190
crygm2d7
crystallin, gamma M2d7
chr10_-_44180588 2.81 ENSDART00000145404
crybb1
crystallin, beta B1
chr6_+_41466199 2.73 ENSDART00000177439
twf2a
twinfilin actin-binding protein 2a
chr13_-_37144297 2.70

chr9_-_22318918 2.64 ENSDART00000124272
crygm2d17
crystallin, gamma M2d17
chr20_+_45989418 2.64 ENSDART00000131169
bmp2b
bone morphogenetic protein 2b
chr18_-_15405161 2.62 ENSDART00000031752
rfx4
regulatory factor X, 4
chr11_+_25022419 2.57

chr9_-_22470612 2.57 ENSDART00000123763
crygm2d3
crystallin, gamma M2d3
chr1_-_44476084 2.56 ENSDART00000034549
zgc:111983
zgc:111983
chr17_+_381715 2.55 ENSDART00000162898
si:rp71-62i8.1
si:rp71-62i8.1
chr3_-_29846530 2.55 ENSDART00000077111
hsd17b14
hydroxysteroid (17-beta) dehydrogenase 14
chr15_+_24708696 2.54 ENSDART00000043292
smtnl
smoothelin, like
chr13_-_30515486 2.51 ENSDART00000139607
zcchc24
zinc finger, CCHC domain containing 24
chr9_-_22394674 2.51 ENSDART00000101869
crygm2d12
crystallin, gamma M2d12
chr19_+_3713027 2.44 ENSDART00000125673
nedd9
neural precursor cell expressed, developmentally down-regulated 9
chr16_+_53238110 2.44 ENSDART00000102170
CABZ01053976.1
ENSDARG00000069929
chr19_-_47897712 2.42

chr6_+_59788008 2.38

chr4_-_1346961 2.34 ENSDART00000164623
ptn
pleiotrophin
chr16_+_33702010 2.33 ENSDART00000143757
fhl3a
four and a half LIM domains 3a
chr11_-_29891067 2.31 ENSDART00000172106
scml2
sex comb on midleg-like 2 (Drosophila)
chr5_+_26925238 2.31 ENSDART00000051491
sfrp1a
secreted frizzled-related protein 1a
chr5_+_26840147 2.31 ENSDART00000064701
loxl2b
lysyl oxidase-like 2b
chr2_+_33399405 2.27 ENSDART00000137207
slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr20_+_34679181 2.26

chr9_-_22434581 2.26 ENSDART00000114943
crygm2d4
crystallin, gamma M2d4
chr9_-_22488422 2.24 ENSDART00000124600
crygm2d21
crystallin, gamma M2d21
chr3_-_55995924 2.20 ENSDART00000167356
tfap4
transcription factor AP-4 (activating enhancer binding protein 4)
chr4_-_25282256 2.18 ENSDART00000066936
tmem110l
transmembrane protein 110, like
chr10_-_22881453 2.17

chr9_-_22528568 2.15 ENSDART00000134805
crygm2d1
crystallin, gamma M2d1
chr8_+_28240085 2.15 ENSDART00000110857
fam212b
family with sequence similarity 212, member B
chr20_-_17006936 2.10 ENSDART00000012859
psma6b
proteasome subunit alpha 6b
chr7_+_28862183 2.07 ENSDART00000052346
gnao1b
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr1_-_20218263 2.04 ENSDART00000078271
cpe
carboxypeptidase E
chr3_+_33168814 2.02 ENSDART00000114023
hspb9
heat shock protein, alpha-crystallin-related, 9
chr3_-_18426055 2.00 ENSDART00000122968
aqp8b
aquaporin 8b
chr13_-_31304614 1.96

chr13_-_39821399 1.95 ENSDART00000056996
sfrp5
secreted frizzled-related protein 5
chr18_-_8697347 1.93 ENSDART00000093131
FRMD4A
FERM domain containing 4A
chr21_-_13571753 1.92 ENSDART00000065819
clic3
chloride intracellular channel 3
chr19_+_42491275 1.91

chr25_-_325847 1.90 ENSDART00000059514
prickle1a
prickle homolog 1a
chr5_-_30015572 1.89 ENSDART00000147769
si:ch211-117m20.5
si:ch211-117m20.5
chr16_-_44575942 1.88

chr7_-_29811734 1.88 ENSDART00000075600
tspan3b
tetraspanin 3b
chr10_-_44441481 1.86 ENSDART00000160231
sbno1
strawberry notch homolog 1 (Drosophila)
chr4_-_25282161 1.84 ENSDART00000066936
tmem110l
transmembrane protein 110, like
chr19_-_39048324 1.82 ENSDART00000086717
col16a1
collagen, type XVI, alpha 1
chr18_-_11216447 1.81 ENSDART00000040500
tspan9a
tetraspanin 9a
chr19_-_7069920 1.79 ENSDART00000145741
znf384l
zinc finger protein 384 like
chr19_+_3925188 1.77

chr1_+_38834751 1.76 ENSDART00000137676
tenm3
teneurin transmembrane protein 3
chr3_-_13942505 1.74

chr5_-_15774816 1.71 ENSDART00000090684
kremen1
kringle containing transmembrane protein 1
chr6_+_30441419 1.70

chr25_+_5695630 1.70 ENSDART00000161035
C12orf75
chromosome 12 open reading frame 75
chr21_+_25651712 1.68 ENSDART00000135123
si:dkey-17e16.17
si:dkey-17e16.17
chr25_+_35901081 1.66 ENSDART00000042271
ENSDART00000158027
irx3b
iroquois homeobox 3b
chr23_+_6298911 1.60 ENSDART00000139795
syt2a
synaptotagmin IIa
KN150131v1_+_59098 1.60 ENSDART00000175590
CABZ01064941.1
ENSDARG00000106550
chr7_-_26036887 1.60 ENSDART00000146935
zgc:77439
zgc:77439
chr5_+_26925392 1.59 ENSDART00000051491
sfrp1a
secreted frizzled-related protein 1a
chr10_-_39210658 1.59 ENSDART00000150193
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr14_-_32877752 1.59 ENSDART00000163046
si:dkey-31j3.11
si:dkey-31j3.11
chr15_-_10345337 1.57

chr9_-_56692366 1.53

chr24_+_14302079 1.50 ENSDART00000168059
prdm14
PR domain containing 14
chr9_+_907908 1.50 ENSDART00000144114
dbi
diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
chr18_-_15963983 1.47 ENSDART00000127769
plekhg7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr9_-_31714290 1.46 ENSDART00000127214
tmtc4
transmembrane and tetratricopeptide repeat containing 4
chr1_-_19001718 1.46 ENSDART00000143303
BX323590.2
ENSDARG00000095388
chr11_-_6004509 1.46 ENSDART00000108628
ano8b
anoctamin 8b
chr17_+_33423057 1.44 ENSDART00000032827
zgc:162964
zgc:162964
chr25_-_28691412 1.44 ENSDART00000067066
parp6b
poly (ADP-ribose) polymerase family, member 6b
chr9_-_22324699 1.42 ENSDART00000175417
ENSDART00000101902
crygm2d8
crystallin, gamma M2d8
chr24_-_42038250 1.42 ENSDART00000171380
top1mt
topoisomerase (DNA) I, mitochondrial
chr16_+_5778650 1.42 ENSDART00000131575
zgc:158689
zgc:158689
chr14_-_6822151 1.41 ENSDART00000171311
si:ch73-43g23.1
si:ch73-43g23.1
chr13_-_16126849 1.39 ENSDART00000079745
zgc:110045
zgc:110045
chr24_-_16995194 1.38 ENSDART00000111079
CR376737.1
ENSDARG00000077318
chr2_+_33907298 1.38

chr5_+_37861949 1.38 ENSDART00000144425
gltpd2
glycolipid transfer protein domain containing 2
chr11_+_6809190 1.36 ENSDART00000104289
rab3ab
RAB3A, member RAS oncogene family, b
chr16_+_33701759 1.36 ENSDART00000143757
fhl3a
four and a half LIM domains 3a
chr16_-_33105847 1.36

chr4_+_26507297 1.35 ENSDART00000160652
iqsec3a
IQ motif and Sec7 domain 3a
chr23_-_7892862 1.33 ENSDART00000157612
ENSDART00000165427
myt1b
myelin transcription factor 1b
chr13_-_14978365 1.33

chr11_-_1374026 1.31 ENSDART00000172953
rpl29
ribosomal protein L29
chr14_-_47688669 1.30 ENSDART00000113285
tapt1a
transmembrane anterior posterior transformation 1a
chr21_-_37404394 1.30 ENSDART00000129439
BX649250.1
ENSDARG00000091187
chr22_+_26423320 1.30 ENSDART00000044085
ENSDARG00000034211
ENSDARG00000034211
chr22_+_26616977 1.29 ENSDART00000171972
ENSDART00000083351
ENSDARG00000034211
ENSDARG00000034211
chr24_-_40968409 1.29 ENSDART00000169315
ENSDART00000171543
smyhc1
slow myosin heavy chain 1
chr19_+_4996328 1.28 ENSDART00000165082
ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr18_-_48498261 1.28 ENSDART00000146346
kcnj1a.6
potassium inwardly-rectifying channel, subfamily J, member 1a, tandem duplicate 6
chr24_-_16994956 1.26 ENSDART00000111079
CR376737.1
ENSDARG00000077318
chr1_+_28293053 1.26 ENSDART00000075539
cryaa
crystallin, alpha A
chr8_-_2375664 1.25 ENSDART00000144017
vdac3
voltage-dependent anion channel 3
chr25_+_36872560 1.25 ENSDART00000163178
slc10a3
solute carrier family 10, member 3
chr19_-_22983970 1.25 ENSDART00000160153
pleca
plectin a
chr4_-_71353374 1.25

chr1_+_1964902 1.23 ENSDART00000138396
mbnl2
muscleblind-like splicing regulator 2
chr15_+_1238615 1.23 ENSDART00000167760
ENSDART00000163827
mfsd1
major facilitator superfamily domain containing 1
chr17_+_33422832 1.22 ENSDART00000032827
zgc:162964
zgc:162964
chr15_+_29823641 1.22

chr15_-_2762950 1.21 ENSDART00000108856
si:ch211-235m3.5
si:ch211-235m3.5
chr15_+_9321225 1.20 ENSDART00000055554
slc37a4a
solute carrier family 37 (glucose-6-phosphate transporter), member 4a
chr13_-_49695322 1.18

chr19_-_7069850 1.17 ENSDART00000145741
znf384l
zinc finger protein 384 like
chr7_+_38008155 1.15 ENSDART00000169927
lrp3
low density lipoprotein receptor-related protein 3
chr10_+_8670564 1.13 ENSDART00000129643
aplnrb
apelin receptor b
chr8_-_6875110 1.11 ENSDART00000014915
asb6
ankyrin repeat and SOCS box containing 6
chr18_-_16934961 1.10 ENSDART00000122102
wee1
WEE1 G2 checkpoint kinase
chr6_-_32000976 1.08 ENSDART00000132280
ror1
receptor tyrosine kinase-like orphan receptor 1
chr11_-_11487856 1.07 ENSDART00000030103
krt94
keratin 94
chr13_+_51005155 1.06

chr3_-_29846789 1.06 ENSDART00000077111
hsd17b14
hydroxysteroid (17-beta) dehydrogenase 14
chr12_-_29190576 1.06 ENSDART00000153458
sh2d4bb
SH2 domain containing 4Bb
chr23_-_3760604 1.05 ENSDART00000143731
pacsin1a
protein kinase C and casein kinase substrate in neurons 1a
chr17_+_8874210 1.04

chr16_+_6693574 1.04

chr14_+_15698814 1.04

chr23_-_45356039 1.03 ENSDART00000067630
ENSDARG00000039901
ENSDARG00000039901
chr10_+_39211384 1.01

chr22_-_29387056 0.99 ENSDART00000121599
pdgfba
platelet-derived growth factor beta polypeptide a
chr8_-_20213672 0.98 ENSDART00000136911
acer1
alkaline ceramidase 1
chr5_+_14850708 0.98 ENSDART00000140990
ENSDART00000137287
pebp1
phosphatidylethanolamine binding protein 1
chr6_+_60190849 0.96

chr13_-_36577270 0.95 ENSDART00000044357
cdkl1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr9_-_48202667 0.94

chr25_+_5695588 0.94 ENSDART00000161035
C12orf75
chromosome 12 open reading frame 75
chr14_+_33073643 0.93 ENSDART00000052780
ndufa1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1
chr16_+_24046789 0.92

chr6_+_7257078 0.92 ENSDART00000049339
sox21a
SRY (sex determining region Y)-box 21a
chr4_+_7499654 0.92 ENSDART00000158999
tnnt2e
troponin T2e, cardiac
chr10_-_39211281 0.92 ENSDART00000148825
slc37a4b
solute carrier family 37 (glucose-6-phosphate transporter), member 4b
chr2_+_24718602 0.92 ENSDART00000022379
nr2f6a
nuclear receptor subfamily 2, group F, member 6a
chr10_+_29966381 0.92 ENSDART00000141549
hspa8
heat shock protein 8
chr19_-_39048402 0.91 ENSDART00000086717
col16a1
collagen, type XVI, alpha 1
chr20_+_316191 0.91 ENSDART00000104807
si:dkey-119m7.4
si:dkey-119m7.4
chr7_+_30803603 0.88 ENSDART00000173805
tjp1a
tight junction protein 1a
chr23_+_24161550 0.88 ENSDART00000145159
ttll10
tubulin tyrosine ligase-like family, member 10
chr11_+_23012136 0.87 ENSDART00000110152
csf1a
colony stimulating factor 1a (macrophage)
chr1_+_23093114 0.86

chr19_-_22984081 0.82 ENSDART00000160153
pleca
plectin a
chr16_-_31835463 0.82 ENSDART00000148389
chd4b
chromodomain helicase DNA binding protein 4b
chr5_-_21520111 0.82

chr7_+_26980284 0.80 ENSDART00000173962
sox6
SRY (sex determining region Y)-box 6
chr23_-_4919504 0.80 ENSDART00000133701
slc6a1a
solute carrier family 6 (neurotransmitter transporter), member 1a
chr22_-_62082 0.80 ENSDART00000166010
ENSDART00000125700
mrpl20
mitochondrial ribosomal protein L20
chr3_-_34417082 0.78 ENSDART00000166623
sept9a
septin 9a
chr1_-_15814788 0.78 ENSDART00000169081
mtmr7b
myotubularin related protein 7b
chr8_-_46903869 0.77 ENSDART00000161462
acot7
acyl-CoA thioesterase 7
chr3_-_19346061 0.77 ENSDART00000162248
CU571315.3
ENSDARG00000101990
chr17_-_15141309 0.77 ENSDART00000103405
gch1
GTP cyclohydrolase 1
chr13_-_30515304 0.76 ENSDART00000139607
zcchc24
zinc finger, CCHC domain containing 24
chr23_-_39858232 0.75 ENSDART00000160853
minos1
mitochondrial inner membrane organizing system 1
chr15_+_43683110 0.74 ENSDART00000168589
ctsc
cathepsin C
chr10_-_14587464 0.71 ENSDART00000057865
ier3ip1
immediate early response 3 interacting protein 1
chr13_-_29294141 0.71 ENSDART00000026765
slc18a3a
solute carrier family 18 (vesicular acetylcholine transporter), member 3a
chr5_+_52198613 0.70 ENSDART00000162459
scarb2a
scavenger receptor class B, member 2a
chr8_+_24725855 0.70 ENSDART00000078656
slc16a4
solute carrier family 16, member 4
chr16_+_68014 0.70 ENSDART00000159652
sox4b
SRY (sex determining region Y)-box 4b
chr25_-_15117843 0.69 ENSDART00000031499
wt1a
wilms tumor 1a
chr2_-_30005139 0.69 ENSDART00000146968
cnpy1
canopy1
chr16_-_5821719 0.68 ENSDART00000136655
ndufa3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3
chr5_-_32686309 0.66 ENSDART00000117288
SNORD24
Small nucleolar RNA SNORD24
chr5_-_56534037 0.65 ENSDART00000171252
man2a1
mannosidase, alpha, class 2A, member 1
chr21_+_35292807 0.64 ENSDART00000130626
rars
arginyl-tRNA synthetase
chr16_+_54001592 0.64

chr23_-_4175790 0.64 ENSDART00000109807
ENSDARG00000076299
ENSDARG00000076299
chr14_-_32877816 0.64 ENSDART00000163046
si:dkey-31j3.11
si:dkey-31j3.11
chr20_+_36720896 0.64 ENSDART00000062895
srp9
signal recognition particle 9
chr14_-_34431408 0.64 ENSDART00000141157
ENSDART00000160598
ENSDART00000150413
ablim3
actin binding LIM protein family, member 3
chr10_+_29966252 0.62 ENSDART00000141549
hspa8
heat shock protein 8
chr1_-_1254253 0.61 ENSDART00000130697
runx1
runt-related transcription factor 1
chr9_+_41776713 0.61

chr14_-_2179471 0.59 ENSDART00000157401
pcdh2g1
protocadherin 2 gamma 1
chr14_-_38734382 0.59 ENSDART00000030509
glra4a
glycine receptor, alpha 4a
chr24_+_33697332 0.58

chr4_+_8007802 0.58 ENSDART00000014036
optn
optineurin
chr9_-_30560440 0.58 ENSDART00000079068
asb11
ankyrin repeat and SOCS box containing 11
chr9_-_34690993 0.58 ENSDART00000114043
ppp2r3b
protein phosphatase 2, regulatory subunit B'', beta

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
1.0 3.1 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578)
0.9 2.6 GO:0061130 branching involved in pancreas morphogenesis(GO:0061114) pancreatic bud formation(GO:0061130) pancreas field specification(GO:0061131)
0.8 2.3 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.6 1.9 GO:0061031 endodermal digestive tract morphogenesis(GO:0061031)
0.6 1.8 GO:0070983 dendrite guidance(GO:0070983) regulation of homophilic cell adhesion(GO:1903385)
0.6 2.3 GO:0099565 chemical synaptic transmission, postsynaptic(GO:0099565)
0.5 2.4 GO:0090527 actin filament reorganization(GO:0090527)
0.4 2.2 GO:0048901 anterior lateral line neuromast development(GO:0048901) anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.4 1.3 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.4 27.7 GO:0007601 visual perception(GO:0007601)
0.3 1.4 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.3 1.3 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 1.7 GO:0035777 pronephric distal tubule development(GO:0035777)
0.3 1.9 GO:1902946 protein localization to early endosome(GO:1902946)
0.3 0.9 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 0.8 GO:1990092 calcium-dependent self proteolysis(GO:1990092)
0.3 1.5 GO:0034969 histone arginine methylation(GO:0034969)
0.2 0.7 GO:0042908 xenobiotic transport(GO:0042908)
0.2 1.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.2 0.6 GO:0030852 regulation of collagen metabolic process(GO:0010712) regulation of granulocyte differentiation(GO:0030852) plasminogen activation(GO:0031639) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246) regulation of neutrophil differentiation(GO:0045658)
0.2 0.8 GO:0061036 positive regulation of chondrocyte differentiation(GO:0032332) positive regulation of cartilage development(GO:0061036)
0.2 2.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 0.8 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.2 0.9 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.2 1.4 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249) positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 1.0 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.2 0.7 GO:0072149 visceral serous pericardium development(GO:0061032) glomerular visceral epithelial cell fate commitment(GO:0072149) glomerular epithelial cell fate commitment(GO:0072314)
0.2 0.5 GO:0045475 locomotor rhythm(GO:0045475)
0.1 1.9 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
0.1 2.2 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 2.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:0002762 negative regulation of myeloid leukocyte differentiation(GO:0002762)
0.1 1.0 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.1 3.8 GO:0061386 closure of optic fissure(GO:0061386)
0.1 0.4 GO:1901998 toxin transport(GO:1901998)
0.1 0.8 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 1.1 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.1 1.4 GO:0006265 DNA topological change(GO:0006265)
0.1 2.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 2.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.7 GO:0006013 mannose metabolic process(GO:0006013)
0.1 1.0 GO:0097320 membrane tubulation(GO:0097320) positive regulation of dendrite development(GO:1900006)
0.1 0.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.5 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.1 0.6 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 1.3 GO:1902017 regulation of cilium assembly(GO:1902017)
0.1 1.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.1 1.0 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.2 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.1 0.6 GO:0006448 regulation of translational elongation(GO:0006448)
0.1 1.2 GO:0047496 vesicle transport along microtubule(GO:0047496)
0.0 3.2 GO:0021515 cell differentiation in spinal cord(GO:0021515)
0.0 2.6 GO:0045010 actin nucleation(GO:0045010)
0.0 2.3 GO:0051781 positive regulation of cell division(GO:0051781)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 4.0 GO:0006936 muscle contraction(GO:0006936)
0.0 1.0 GO:0043409 negative regulation of MAPK cascade(GO:0043409)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.5 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 1.3 GO:0006821 chloride transport(GO:0006821)
0.0 0.1 GO:0035094 response to nicotine(GO:0035094)
0.0 0.6 GO:0030032 lamellipodium assembly(GO:0030032) lamellipodium organization(GO:0097581)
0.0 0.5 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.7 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.8 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.3 GO:0042476 odontogenesis(GO:0042476)
0.0 2.0 GO:0016485 protein processing(GO:0016485)
0.0 1.1 GO:0007093 mitotic cell cycle checkpoint(GO:0007093)
0.0 0.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 1.2 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.7 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.0 0.4 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 0.4 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0060231 mesenchymal to epithelial transition(GO:0060231)
0.0 0.1 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 1.4 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.3 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.2 0.9 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 2.2 GO:0030056 hemidesmosome(GO:0030056)
0.2 2.1 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 1.3 GO:0046930 pore complex(GO:0046930)
0.1 0.6 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.1 0.7 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 4.0 GO:0005865 striated muscle thin filament(GO:0005865) myofilament(GO:0036379)
0.1 2.9 GO:0016342 catenin complex(GO:0016342)
0.1 2.5 GO:0034707 chloride channel complex(GO:0034707)
0.1 4.3 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 3.3 GO:0005581 collagen trimer(GO:0005581)
0.0 2.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0070938 contractile ring(GO:0070938)
0.0 0.2 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 1.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.6 GO:0005884 actin filament(GO:0005884)
0.0 0.8 GO:0005940 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 1.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 3.9 GO:0030424 axon(GO:0030424)
0.0 13.0 GO:0005615 extracellular space(GO:0005615)
0.0 1.0 GO:0016459 myosin complex(GO:0016459)
0.0 1.3 GO:0036064 ciliary basal body(GO:0036064)
0.0 1.1 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0030057 desmosome(GO:0030057)
0.0 0.9 GO:0070160 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 1.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 27.7 GO:0005212 structural constituent of eye lens(GO:0005212)
0.4 1.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.4 1.3 GO:0015288 porin activity(GO:0015288)
0.4 1.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 2.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 2.0 GO:0015250 water channel activity(GO:0015250)
0.3 1.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 2.6 GO:0070700 BMP receptor binding(GO:0070700)
0.3 3.1 GO:0005343 sodium:amino acid symporter activity(GO:0005283) organic acid:sodium symporter activity(GO:0005343)
0.3 1.3 GO:0033149 FFAT motif binding(GO:0033149)
0.2 3.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 2.1 GO:0051429 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 4.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.2 2.2 GO:0030506 ankyrin binding(GO:0030506)
0.2 0.7 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.2 2.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 0.8 GO:0017040 ceramidase activity(GO:0017040)
0.1 8.7 GO:0008201 heparin binding(GO:0008201)
0.1 1.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.4 GO:0015230 FAD transmembrane transporter activity(GO:0015230)
0.1 0.6 GO:0008312 7S RNA binding(GO:0008312)
0.1 1.0 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.9 GO:0030172 troponin C binding(GO:0030172) troponin I binding(GO:0031013)
0.1 0.3 GO:0039706 co-receptor binding(GO:0039706) receptor antagonist activity(GO:0048019)
0.1 5.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 6.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.6 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.1 0.8 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.5 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.5 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 3.0 GO:0045296 cadherin binding(GO:0045296)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.3 GO:0005123 death receptor binding(GO:0005123)
0.0 0.7 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 2.6 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.0 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.5 GO:0019894 kinesin binding(GO:0019894)
0.0 1.0 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.3 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.4 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.8 GO:0004438 phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0 0.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 10.9 GO:0003779 actin binding(GO:0003779)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.6 GO:0015293 symporter activity(GO:0015293)
0.0 0.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.8 GO:0019843 rRNA binding(GO:0019843)
0.0 2.5 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.1 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 1.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.9 GO:0008083 growth factor activity(GO:0008083)
0.0 0.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.0 GO:0003678 DNA helicase activity(GO:0003678)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 3.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 2.7 NABA COLLAGENS Genes encoding collagen proteins
0.1 1.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 4.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 2.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.7 PID ATM PATHWAY ATM pathway
0.0 2.2 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 1.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.2 3.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 2.0 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 0.8 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 0.6 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 2.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 4.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 3.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation