ISMARA results: thrb

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Results for thrb

Z-value: 0.29

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Transcription factors associated with thrb

Gene Symbol	Gene ID	Gene Info
thrb NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000021163	thyroid hormone receptor beta

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
thrb	dr10_dc_chr19_-_18199573_18199635	0.53	3.4e-02	Click!

Activity profile of thrb motif

Sorted Z-values of thrb motif

Network of associatons between targets according to the STRING database.

First level regulatory network of thrb

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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr2_+_19514967 Show fit	0.41	ENSDART00000166073	elovl1a NCBI UniProt ZFIN ENSEMBL Google Show fit	ELOVL fatty acid elongase 1a
chr2_+_19515120 Show fit	0.37	ENSDART00000166073	elovl1a NCBI UniProt ZFIN ENSEMBL Google Show fit	ELOVL fatty acid elongase 1a
chr2_+_19514886 Show fit	0.36	ENSDART00000166073	elovl1a NCBI UniProt ZFIN ENSEMBL Google Show fit	ELOVL fatty acid elongase 1a
chr13_-_36440277 Show fit	0.35	ENSDART00000030133	synj2bp NCBI UniProt ZFIN ENSEMBL Google Show fit	synaptojanin 2 binding protein
chr15_-_35020312 Show fit	0.35	ENSDART00000154094	mgat1a NCBI UniProt ZFIN ENSEMBL Google Show fit	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr15_-_34550732 Show fit	0.30	ENSDART00000139934	agmo NCBI UniProt ZFIN ENSEMBL Google Show fit	alkylglycerol monooxygenase
chr19_+_30266913 Show fit	0.27	ENSDART00000109729	si:ch73-130a3.4 NCBI UniProt ZFIN ENSEMBL Google Show fit	si:ch73-130a3.4
chr15_-_35020250 Show fit	0.25	ENSDART00000154094	mgat1a NCBI UniProt ZFIN ENSEMBL Google Show fit	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase a
chr16_+_17857553 Show fit	0.24	ENSDART00000148878	them4 NCBI UniProt ZFIN ENSEMBL Google Show fit	thioesterase superfamily member 4
chr20_+_27398061 Show fit	0.23	ENSDART00000153440	BX255913.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ENSDARG00000096709
chr17_+_30826890 Show fit	0.22	ENSDART00000149600	tpp1 NCBI UniProt ZFIN ENSEMBL Google Show fit	tripeptidyl peptidase I
chr6_+_60117223 Show fit	0.22	ENSDART00000008243	prelid3b NCBI UniProt ZFIN ENSEMBL Google Show fit	PRELI domain containing 3
chr2_-_5287507 Show fit	0.21	ENSDART00000063384	phb2a NCBI UniProt ZFIN ENSEMBL Google Show fit	prohibitin 2a
chr3_+_34716635 Show fit	0.19	ENSDART00000055263	itga3a NCBI UniProt ZFIN ENSEMBL Google Show fit	integrin, alpha 3a
chr2_-_5287404 Show fit	0.18	ENSDART00000063384	phb2a NCBI UniProt ZFIN ENSEMBL Google Show fit	prohibitin 2a
chr14_+_37506462 Show fit	0.14	ENSDART00000174790 ENSDART00000179610 ENSDART00000179048	CU104743.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ENSDARG00000109062
chr6_-_42292607 Show fit	0.02	ENSDART00000064969	tex264a NCBI UniProt ZFIN ENSEMBL Google Show fit	testis expressed 264a
chr24_-_1026977 Show fit	0.01	ENSDART00000147508	ralaa NCBI UniProt ZFIN ENSEMBL Google Show fit	v-ral simian leukemia viral oncogene homolog Aa (ras related)

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	1.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.4	GO:0097120	receptor localization to synapse(GO:0097120)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	GO:0098839	postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1	0.2	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.1	0.3	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1	0.2	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	1.1	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network