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Results for tp73

Z-value: 0.56

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Transcription factors associated with tp73

Gene Symbol Gene ID Gene Info
tp73
ENSDARG00000017953 tumor protein p73

Activity profile of tp73 motif

Sorted Z-values of tp73 motif

Network of associatons between targets according to the STRING database.

Top targets:

Promoter Score Transcript Gene Gene Info
chr11_+_12192624 2.22 ENSDART00000041914
ENSDART00000166887
si:ch211-156l18.7
si:ch211-156l18.7
chr11_+_12192712 1.02 ENSDART00000041914
ENSDART00000166887
si:ch211-156l18.7
si:ch211-156l18.7
chr21_+_15339960 0.87 ENSDART00000137491
si:dkey-11o15.10
si:dkey-11o15.10
chr9_-_30560440 0.85 ENSDART00000079068
asb11
ankyrin repeat and SOCS box containing 11
chr7_+_30355221 0.56 ENSDART00000173533
ENSDART00000052541
ccnb2
cyclin B2
chr2_+_37855019 0.48 ENSDART00000113337
parp2
poly (ADP-ribose) polymerase 2
chr18_+_44775384 0.46 ENSDART00000016271
ilvbl
ilvB (bacterial acetolactate synthase)-like
chr25_-_3619590 0.41 ENSDART00000037973
morc2
MORC family CW-type zinc finger 2
chr5_+_6291842 0.41 ENSDART00000148663
elac1
elaC ribonuclease Z 1
chr23_+_39454172 0.41 ENSDART00000149819
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr23_+_25224687 0.37

chr23_+_25224768 0.35

chr4_+_23406078 0.35 ENSDART00000139543
mdm2
MDM2 oncogene, E3 ubiquitin protein ligase
chr18_-_38289008 0.33 ENSDART00000139519
caprin1b
cell cycle associated protein 1b
chr11_-_22450525 0.28

chr16_+_39246663 0.26 ENSDART00000017017
zdhhc3a
zinc finger, DHHC-type containing 3a
chr21_-_26379011 0.25

chr24_+_31522539 0.25 ENSDART00000126380
cnbd1
cyclic nucleotide binding domain containing 1
chr13_-_23825684 0.25 ENSDART00000133646
phactr2
phosphatase and actin regulator 2
chr11_-_21203114 0.25 ENSDART00000080051
RASSF5
Ras association domain family member 5
chr11_-_21203166 0.24 ENSDART00000080051
RASSF5
Ras association domain family member 5
chr11_-_22450327 0.24

chr14_+_21835107 0.23 ENSDART00000109065
ccng1
cyclin G1
chr10_+_2559774 0.19 ENSDART00000126937
wu:fb59d01
wu:fb59d01
chr16_-_21683782 0.19 ENSDART00000146914
mpp6a
membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6)
chr25_+_3619832 0.19

chr13_+_17333378 0.18 ENSDART00000139245
CT025897.1
ENSDARG00000093577
chr25_-_13562597 0.17 ENSDART00000045488
csnk2a2b
casein kinase 2, alpha prime polypeptide b
chr2_+_36110584 0.15 ENSDART00000163189
BX681417.4
ENSDARG00000101668
chr6_-_10855968 0.15 ENSDART00000127209
pttg1ipa
PTTG1 interacting protein a
chr9_-_3700395 0.14 ENSDART00000102900
sp5a
Sp5 transcription factor a
chr4_-_23405867 0.14

chr17_-_15520620 0.12 ENSDART00000023320
fyna
FYN proto-oncogene, Src family tyrosine kinase a
chr23_+_39453929 0.11 ENSDART00000102843
src
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr2_+_11335810 0.11 ENSDART00000055737
tyw3
tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
chr2_-_22162431 0.08 ENSDART00000135230
chd7
chromodomain helicase DNA binding protein 7
chr25_-_3619663 0.08 ENSDART00000037973
morc2
MORC family CW-type zinc finger 2
chr13_-_17333287 0.08 ENSDART00000145499
c13h10orf11
c13h10orf11 homolog (H. sapiens)
chr22_+_8506974 0.08 ENSDART00000132998
si:ch73-27e22.7
si:ch73-27e22.7
chr12_-_3042573 0.07 ENSDART00000002867
ENSDART00000126315
rfng
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr7_-_73625262 0.07 ENSDART00000041385
zgc:163061
zgc:163061
chr20_-_3873641 0.07 ENSDART00000113132
gnpat
glyceronephosphate O-acyltransferase
chr25_-_13562558 0.07 ENSDART00000045488
csnk2a2b
casein kinase 2, alpha prime polypeptide b
chr22_+_39012456 0.06 ENSDART00000176985
CABZ01044615.1
ENSDARG00000108810
chr25_-_14327948 0.05 ENSDART00000073609
prmt7
protein arginine methyltransferase 7
KN150108v1_-_8893 0.05 ENSDART00000167033
ENSDARG00000100513
ENSDARG00000100513
chr4_+_13453833 0.04 ENSDART00000145069
dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr11_+_24060826 0.04 ENSDART00000138487
si:dkey-76p14.2
si:dkey-76p14.2
KN150359v1_+_69830 0.03

chr12_+_22455344 0.03 ENSDART00000172053
capgb
capping protein (actin filament), gelsolin-like b
chr19_+_48166365 0.02

chr2_+_36111019 0.02 ENSDART00000161694
BX681417.4
ENSDARG00000101668
chr13_-_8968136 0.02 ENSDART00000144714
HTRA2 (1 of many)
HtrA serine peptidase 2
chr9_-_34312633 0.02 ENSDART00000000004
slc35a5
solute carrier family 35, member A5
chr1_+_35919158 0.02 ENSDART00000176692
CR762429.1
ENSDARG00000108193
chr24_+_31522601 0.02 ENSDART00000126380
cnbd1
cyclic nucleotide binding domain containing 1
chr3_-_39346621 0.01 ENSDART00000135192
ENSDART00000013553
ENSDART00000167289
zgc:100868
zgc:100868
chr18_+_1583668 0.01

chr4_+_70951703 0.01 ENSDART00000106253
si:cabz01054394.7
si:cabz01054394.7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.2 0.5 GO:0098751 bone cell development(GO:0098751)
0.1 0.3 GO:1904019 epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.1 0.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.4 GO:0042779 tRNA 3'-trailer cleavage(GO:0042779)
0.1 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) regulation of cyclin-dependent protein kinase activity(GO:1904029)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0048798 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.1 0.5 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.1 0.4 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.3 GO:0019705 protein-cysteine S-myristoyltransferase activity(GO:0019705)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.0 0.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition