ISMARA results: twist1a+twist1b+twist3

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Results for twist1a+twist1b+twist3

Z-value: 0.45

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Transcription factors associated with twist1a+twist1b+twist3

Gene Symbol	Gene ID	Gene Info
twist3 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000019646	twist3
twist1a NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000030402	twist family bHLH transcription factor 1a
twist1b NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000076010	twist family bHLH transcription factor 1b

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
twist1a	dr10_dc_chr19_-_2399429_2399450	0.45	7.9e-02	Click!
twist1b	dr10_dc_chr16_+_19926776_19926808	0.18	5.1e-01	Click!
twist3	dr10_dc_chr23_+_2665_2671	0.07	7.8e-01	Click!

Activity profile of twist1a+twist1b+twist3 motif

Sorted Z-values of twist1a+twist1b+twist3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of twist1a+twist1b+twist3

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Promoter	Score	Transcript	Gene	Gene Info
chr4_-_17735989 Show fit	1.06	ENSDART00000016658	chpt1 NCBI UniProt ZFIN ENSEMBL Google Show fit	choline phosphotransferase 1
chr9_-_40212864 Show fit	0.72	ENSDART00000166918	IKZF2 NCBI UniProt ZFIN ENSEMBL Google Show fit	IKAROS family zinc finger 2
chr14_-_30747448 Show fit	0.67	ENSDART00000002250	hs6st2 NCBI UniProt ZFIN ENSEMBL Google Show fit	heparan sulfate 6-O-sulfotransferase 2
chr14_-_30747259 Show fit	0.60	ENSDART00000002250	hs6st2 NCBI UniProt ZFIN ENSEMBL Google Show fit	heparan sulfate 6-O-sulfotransferase 2
chr14_+_47229400 Show fit	0.57	ENSDART00000136045	mgst2 NCBI UniProt ZFIN ENSEMBL Google Show fit	microsomal glutathione S-transferase 2
chr17_-_25865861 Show fit	0.55
chr20_-_22036656 Show fit	0.46	ENSDART00000152290	daam1b NCBI UniProt ZFIN ENSEMBL Google Show fit	dishevelled associated activator of morphogenesis 1b
chr13_-_31165867 Show fit	0.43	ENSDART00000030946	prdm8 NCBI UniProt ZFIN ENSEMBL Google Show fit	PR domain containing 8
chr4_-_12792010 Show fit	0.41	ENSDART00000067131	irak3 NCBI UniProt ZFIN ENSEMBL Google Show fit	interleukin-1 receptor-associated kinase 3
chr1_-_5284684 Show fit	0.41

Showing 1 to 10 of 37 entries

Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.5	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1	0.6	GO:0006691	leukotriene metabolic process(GO:0006691) leukotriene biosynthetic process(GO:0019370)
0.1	0.4	GO:0002755	MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.0	0.4	GO:0014003	oligodendrocyte development(GO:0014003)
0.1	0.3	GO:0010657	negative regulation of muscle cell apoptotic process(GO:0010656) muscle cell apoptotic process(GO:0010657) striated muscle cell apoptotic process(GO:0010658) regulation of muscle cell apoptotic process(GO:0010660) regulation of striated muscle cell apoptotic process(GO:0010662) negative regulation of striated muscle cell apoptotic process(GO:0010664)
0.0	0.3	GO:0006448	regulation of translational elongation(GO:0006448)
0.0	0.2	GO:0006828	manganese ion transport(GO:0006828)

Showing 1 to 7 of 7 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)

Showing 1 to 1 of 1 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.5	GO:0017095	heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.4	1.1	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.2	0.6	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
0.1	0.3	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.3	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.0	GO:0004383	guanylate cyclase activity(GO:0004383)

Showing 1 to 7 of 7 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Total log-likelihood	Term	Description
0.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.3	PID IL3 PATHWAY	IL3-mediated signaling events

Showing 1 to 3 of 3 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.1	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.4	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.3	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
0.0	0.1	REACTOME INTEGRATION OF PROVIRUS	Genes involved in Integration of provirus

Showing 1 to 6 of 6 entries

Results for twist1a+twist1b+twist3

Z-value: 0.45

Motif logo

Transcription factors associated with twist1a+twist1b+twist3

Activity-expression correlation:

Activity profile of twist1a+twist1b+twist3 motif

Sorted Z-values of twist1a+twist1b+twist3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of twist1a+twist1b+twist3

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: