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Results for vdrb_nr1i2

Z-value: 0.72

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Transcription factors associated with vdrb_nr1i2

Gene Symbol Gene ID Gene Info
vdrb
ENSDARG00000070721 vitamin D receptor b
nr1i2
ENSDARG00000029766 nuclear receptor subfamily 1, group I, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
vdrbdr10_dc_chr6_-_39008833_390090100.591.7e-02Click!
nr1i2dr10_dc_chr9_+_9524547_95245940.322.3e-01Click!

Activity profile of vdrb_nr1i2 motif

Sorted Z-values of vdrb_nr1i2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of vdrb_nr1i2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr9_-_56692366 1.83

chr9_+_10721552 1.81 ENSDART00000061499
cxcr4b
chemokine (C-X-C motif), receptor 4b
chr6_+_50452131 1.48 ENSDART00000155051
mych
myelocytomatosis oncogene homolog
chr3_-_29846530 1.48 ENSDART00000077111
hsd17b14
hydroxysteroid (17-beta) dehydrogenase 14
chr5_-_60671545 1.42

chr13_-_3801122 1.34

chr25_+_17774363 1.27 ENSDART00000136797
btbd10a
BTB (POZ) domain containing 10a
chr2_-_53772219 1.25 ENSDART00000037557
admp
anti-dorsalizing morphogenic protein
chr7_-_23965038 0.97 ENSDART00000010124
slc7a8a
solute carrier family 7 (amino acid transporter light chain, L system), member 8a
chr5_-_36349284 0.85 ENSDART00000047269
h3f3b.1
H3 histone, family 3B.1
chr19_-_43468872 0.81

chr21_+_30434147 0.80 ENSDART00000147375
snx12
sorting nexin 12
chr7_-_11812634 0.80 ENSDART00000101537
mex3b
mex-3 RNA binding family member B
chr19_+_30210743 0.76 ENSDART00000167803
marcksl1b
MARCKS-like 1b
chr4_-_13922285 0.69 ENSDART00000080334
yaf2
YY1 associated factor 2
chr1_-_18695214 0.58

chr25_+_12397532 0.57 ENSDART00000163508
map1lc3b
microtubule-associated protein 1 light chain 3 beta
chr10_-_20524586 0.55

chr16_+_19730958 0.48 ENSDART00000139357
sp8b
sp8 transcription factor b
chr3_+_19186494 0.45 ENSDART00000111528
kri1
KRI1 homolog
chr6_+_50452229 0.43 ENSDART00000155051
mych
myelocytomatosis oncogene homolog
chr9_-_56692281 0.43

chr13_-_1177857 0.42 ENSDART00000111052
olig3
oligodendrocyte transcription factor 3
chr23_-_45011360 0.42 ENSDART00000129138
mogat3a
monoacylglycerol O-acyltransferase 3a
chr19_+_43468063 0.40 ENSDART00000168263
pum1
pumilio RNA-binding family member 1
chr21_+_5483017 0.39 ENSDART00000160885
stbd1
starch binding domain 1
chr15_-_18110169 0.39

chr23_-_18958008 0.37 ENSDART00000133419
CR847953.1
ENSDARG00000057403
chr20_+_49273889 0.37 ENSDART00000166051
ENSDART00000112689
crnkl1
crooked neck pre-mRNA splicing factor 1
chr7_+_45731077 0.36 ENSDART00000159700
si:ch211-260e23.9
si:ch211-260e23.9
chr3_+_19186724 0.33 ENSDART00000110548
kri1
KRI1 homolog
chr9_-_39190534 0.33

chr23_-_45011264 0.33 ENSDART00000129138
mogat3a
monoacylglycerol O-acyltransferase 3a
chr16_+_19730820 0.33 ENSDART00000079201
sp8b
sp8 transcription factor b
chr23_+_41349364 0.31

chr16_+_32097505 0.31 ENSDART00000039109
leng1
leukocyte receptor cluster (LRC) member 1
chr19_+_43468926 0.29

chr8_-_3287944 0.28 ENSDART00000057874
FUT9 (1 of many)
fucosyltransferase 9
chr3_+_22386709 0.27

chr16_+_33041823 0.27 ENSDART00000170157
prss35
protease, serine, 35
chr15_+_2458093 0.27 ENSDART00000082294
ENSDART00000156428
hephl1a
hephaestin-like 1a
chr22_-_16009772 0.26

chr23_+_13106555 0.26

chr16_+_19730756 0.26 ENSDART00000112894
sp8b
sp8 transcription factor b
chr19_-_43468824 0.26

chr12_+_14176424 0.26 ENSDART00000078052
mto1
mitochondrial tRNA translation optimization 1
chr23_+_42488817 0.25 ENSDART00000171459
cyp2aa2
y cytochrome P450, family 2, subfamily AA, polypeptide 2
KN150670v1_-_32201 0.24

chr23_-_21490386 0.23

chr6_+_50452529 0.23 ENSDART00000155051
mych
myelocytomatosis oncogene homolog
chr14_+_21779325 0.22 ENSDART00000106147
slc43a1a
solute carrier family 43 (amino acid system L transporter), member 1a
chr15_-_33782909 0.22 ENSDART00000167705
stard13b
StAR-related lipid transfer (START) domain containing 13b
chr12_+_10096495 0.22 ENSDART00000152212
ENSDART00000127343
smarcd2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr6_-_43679553 0.22 ENSDART00000150128
foxp1b
forkhead box P1b
chr5_+_68943914 0.21 ENSDART00000159594
mthfd2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr23_-_3809640 0.21

chr19_+_30210491 0.19 ENSDART00000167803
marcksl1b
MARCKS-like 1b
chr20_+_230394 0.19 ENSDART00000002661
lama4
laminin, alpha 4
chr15_+_2457956 0.18 ENSDART00000082294
ENSDART00000156428
hephl1a
hephaestin-like 1a
chr14_+_21999898 0.18

chr6_-_39083081 0.17 ENSDART00000021520
eif4bb
eukaryotic translation initiation factor 4Bb
chr21_+_17509116 0.17

chr21_-_25719352 0.16 ENSDART00000002341
cldnc
claudin c
chr10_-_14530112 0.16 ENSDART00000176126
galt
galactose-1-phosphate uridylyltransferase
chr19_+_4102502 0.16 ENSDART00000168112
btr23
bloodthirsty-related gene family, member 23
chr23_-_3809591 0.15

chr22_+_24362712 0.15 ENSDART00000157861
p3h2
prolyl 3-hydroxylase 2
chr9_+_49054601 0.15 ENSDART00000047401
abcb11a
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
chr16_+_6002342 0.15 ENSDART00000060519
ulk4
unc-51 like kinase 4
chr7_+_34235330 0.14 ENSDART00000173957
rfx7
regulatory factor X, 7
chr14_+_45774736 0.14 ENSDART00000139691
rnf44
ring finger protein 44
chr3_+_15245529 0.14

KN150670v1_-_32341 0.13

chr5_+_64175494 0.13 ENSDART00000050863
zgc:101858
zgc:101858
chr10_-_22834248 0.13 ENSDART00000079469
pcolcea
procollagen C-endopeptidase enhancer a
chr9_+_32379130 0.12

chr16_-_35376945 0.12 ENSDART00000162518
ptprub
protein tyrosine phosphatase, receptor type, U, b
chr14_+_31133551 0.12 ENSDART00000173088
ccdc160
coiled-coil domain containing 160
chr17_-_25545464 0.12 ENSDART00000040032
ENSDART00000163447
rtn4ip1
reticulon 4 interacting protein 1
chr19_-_4079427 0.12 ENSDART00000170325
map7d1b
MAP7 domain containing 1b
chr23_-_26150495 0.12 ENSDART00000126299
gdi1
GDP dissociation inhibitor 1
chr19_+_177005 0.12 ENSDART00000111580
tmem65
transmembrane protein 65
chr14_+_46652294 0.12

chr8_+_16954190 0.11 ENSDART00000018934
pde4d
phosphodiesterase 4D, cAMP-specific
chr23_-_3813451 0.11

chr21_-_9313788 0.11

chr21_-_13131290 0.11

chr24_+_9073790 0.11

chr5_+_69096325 0.11 ENSDART00000014649
ugt2a5
UDP glucuronosyltransferase 2 family, polypeptide A5
chr7_+_23798237 0.11 ENSDART00000034218
acin1b
apoptotic chromatin condensation inducer 1b
chr21_+_22842181 0.10 ENSDART00000065562
pcf11
PCF11 cleavage and polyadenylation factor subunit
chr24_+_17201072 0.10 ENSDART00000024722
ezh2
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr13_+_18376642 0.10 ENSDART00000142622
si:ch211-198a12.6
si:ch211-198a12.6
chr16_-_7310925 0.10 ENSDART00000149030
nt5c3a
5'-nucleotidase, cytosolic IIIA
chr7_+_25765060 0.10

chr4_+_30012767 0.09 ENSDART00000150383
znf1128
zinc finger protein 1128
chr10_+_17113205 0.09

chr16_+_19731017 0.09 ENSDART00000139357
sp8b
sp8 transcription factor b
chr5_-_1131341 0.08 ENSDART00000168336
si:zfos-128g4.1
si:zfos-128g4.1
chr15_+_24821561 0.08 ENSDART00000156424
cpda
carboxypeptidase D, a
chr4_-_16356071 0.08 ENSDART00000079521
kera
keratocan
chr1_-_24988461 0.07 ENSDART00000054230
fgg
fibrinogen gamma chain
chr17_-_37107310 0.07 ENSDART00000151921
dnmt3ab
DNA (cytosine-5-)-methyltransferase 3 alpha b
chr12_-_41128584 0.07

chr8_-_2529834 0.07

chr23_-_28881880 0.07 ENSDART00000078167
dffa
DNA fragmentation factor, alpha polypeptide
chr13_-_1177745 0.07 ENSDART00000111052
olig3
oligodendrocyte transcription factor 3
chr16_+_42868905 0.06 ENSDART00000156601
si:ch211-135n15.2
si:ch211-135n15.2
chr19_-_33301572 0.06 ENSDART00000052080
laptm4b
lysosomal protein transmembrane 4 beta
chr1_+_23093114 0.06

chr3_+_15645543 0.06

chr5_+_64175669 0.06 ENSDART00000050863
zgc:101858
zgc:101858
chr2_+_393439 0.06 ENSDART00000122138
mylk4a
myosin light chain kinase family, member 4a
chr4_-_74789596 0.06 ENSDART00000174356
ENSDART00000174313
si:ch73-158p21.3
si:ch73-158p21.3
chr6_-_9394499 0.06 ENSDART00000013066
ercc3
excision repair cross-complementation group 3
chr19_+_43468369 0.06 ENSDART00000165202
pum1
pumilio RNA-binding family member 1
chr5_-_18548689 0.06 ENSDART00000137802
fam214b
family with sequence similarity 214, member B
chr23_-_3809488 0.05

chr24_-_36227334 0.05

chr8_-_13603209 0.05 ENSDART00000080875
b3gnt3
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
chr12_+_16845837 0.05 ENSDART00000138174
slc16a12b
solute carrier family 16, member 12b
chr15_+_2710241 0.05 ENSDART00000157120
CR382327.3
ENSDARG00000097494
chr22_+_24362832 0.05 ENSDART00000157861
p3h2
prolyl 3-hydroxylase 2
chr9_-_6230087 0.05 ENSDART00000032368
tmtops2b
teleost multiple tissue opsin 2b
chr23_-_28881717 0.05 ENSDART00000078167
dffa
DNA fragmentation factor, alpha polypeptide
chr12_+_30538113 0.04 ENSDART00000179355
thbs2b
thrombospondin 2b
chr3_-_31743330 0.04 ENSDART00000155298
limd2
LIM domain containing 2
chr24_+_38267919 0.04 ENSDART00000152019
si:ch211-234p6.5
si:ch211-234p6.5
chr1_-_29885008 0.04 ENSDART00000018827
dachc
dachshund c
chr24_+_19842162 0.04 ENSDART00000123031
CR381686.3
ENSDARG00000094073
chr3_-_2686533 0.04

chr14_+_44312764 0.04 ENSDART00000098643
tomm5
translocase of outer mitochondrial membrane 5 homolog (yeast)
chr5_+_67129480 0.03

chr20_+_19093073 0.03 ENSDART00000147105
tdh
L-threonine dehydrogenase
chr5_+_50432868 0.03 ENSDART00000097466
fam169aa
family with sequence similarity 169, member Aa
chr14_-_20766762 0.03 ENSDART00000164373
si:dkey-74k8.3
si:dkey-74k8.3
chr2_+_30932612 0.03 ENSDART00000132450
ENSDART00000137012
myom1a
myomesin 1a (skelemin)
chr15_+_29460803 0.02 ENSDART00000155198
gdpd5b
glycerophosphodiester phosphodiesterase domain containing 5b
chr23_+_25381458 0.02 ENSDART00000140463
esyt1a
extended synaptotagmin-like protein 1a
chr12_+_16848206 0.02

chr14_-_21779536 0.02

chr14_+_30413350 0.02 ENSDART00000009385
yif1a
Yip1 interacting factor homolog A (S. cerevisiae)
chr6_+_41455676 0.01 ENSDART00000007798
ENSDART00000162135
twf2a
twinfilin actin-binding protein 2a
chr20_+_45530807 0.01

chr3_+_15605789 0.01 ENSDART00000140160
BX914211.1
ENSDARG00000094116
chr4_-_16356247 0.01 ENSDART00000079521
kera
keratocan
chr5_-_18548376 0.01 ENSDART00000133330
fam214b
family with sequence similarity 214, member B
chr18_-_44415397 0.01

chr14_-_25011874 0.01 ENSDART00000159569
htr4
5-hydroxytryptamine receptor 4
chr23_-_3808881 0.01

chr3_-_29846789 0.00 ENSDART00000077111
hsd17b14
hydroxysteroid (17-beta) dehydrogenase 14
chr1_-_44513922 0.00 ENSDART00000014727
ddx39aa
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0002686 negative regulation of leukocyte migration(GO:0002686)
0.2 1.2 GO:0030326 embryonic limb morphogenesis(GO:0030326)
0.2 1.3 GO:0060063 Spemann organizer formation at the embryonic shield(GO:0060063)
0.1 0.8 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.3 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.1 1.2 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.5 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388) galactose catabolic process via UDP-galactose(GO:0033499)
0.0 0.5 GO:0008298 intracellular mRNA localization(GO:0008298)
0.0 0.6 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.7 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.2 GO:0031498 nucleosome disassembly(GO:0006337) chromatin disassembly(GO:0031498) protein-DNA complex disassembly(GO:0032986)
0.0 0.1 GO:0006309 apoptotic DNA fragmentation(GO:0006309) cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0 2.1 GO:0008284 positive regulation of cell proliferation(GO:0008284)
0.0 0.6 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.2 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.1 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0017144 drug metabolic process(GO:0017144) drug catabolic process(GO:0042737) exogenous drug catabolic process(GO:0042738)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0030904 retromer complex(GO:0030904)
0.0 0.4 GO:0071007 Prp19 complex(GO:0000974) U2-type catalytic step 2 spliceosome(GO:0071007)
0.0 1.8 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.8 GO:0030686 90S preribosome(GO:0030686)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0005605 basal lamina(GO:0005605) laminin complex(GO:0043256)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.7 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.1 0.4 GO:2001070 starch binding(GO:2001070)
0.1 0.2 GO:0034057 RNA strand annealing activity(GO:0033592) RNA strand-exchange activity(GO:0034057)
0.1 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797) peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.2 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.0 1.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 1.3 GO:0005125 cytokine activity(GO:0005125)
0.0 0.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation