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Results for vox

Z-value: 0.42

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Transcription factors associated with vox

Gene Symbol Gene ID Gene Info
vox
ENSDARG00000099761 ventral homeobox

Activity profile of vox motif

Sorted Z-values of vox motif

Network of associatons between targets according to the STRING database.

First level regulatory network of vox

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr13_+_22545318 0.99 ENSDART00000143312
zgc:193505
zgc:193505
chr1_+_26330186 0.60 ENSDART00000102322
bnc2
basonuclin 2
chr4_+_5498355 0.60 ENSDART00000150785
mapk11
mitogen-activated protein kinase 11
chr7_+_56405531 0.58

chr25_+_19051298 0.55 ENSDART00000067324
mfge8b
milk fat globule-EGF factor 8 protein b
chr21_-_22510751 0.51 ENSDART00000169870
myo5b
myosin VB
chr7_+_6517248 0.48 ENSDART00000102681
pnp5a
purine nucleoside phosphorylase 5a
chr21_-_17259886 0.47 ENSDART00000114877
gfi1b
growth factor independent 1B transcription repressor
chr6_-_7563110 0.47 ENSDART00000135945
rpsa
ribosomal protein SA
chr17_+_23278879 0.45 ENSDART00000153652
zgc:165461
zgc:165461
chr7_+_23811321 0.42

chr10_+_2952793 0.41

chr7_-_45726932 0.40 ENSDART00000158603
si:ch211-260e23.8
si:ch211-260e23.8
chr16_+_14817799 0.39 ENSDART00000137912
col14a1a
collagen, type XIV, alpha 1a
chr7_+_24770873 0.39 ENSDART00000165314
AL954715.1
ENSDARG00000103682
chr5_+_55598181 0.38 ENSDART00000021159
lhx1b
LIM homeobox 1b
chr13_-_49695322 0.37

chr15_-_15421065 0.35 ENSDART00000106120
ywhag2
3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 2
chr23_+_20183765 0.34 ENSDART00000054664
tnnc1b
troponin C type 1b (slow)
chr3_-_38642067 0.32 ENSDART00000155518
znf281a
zinc finger protein 281a
chr15_-_1858350 0.31 ENSDART00000082026
mmp28
matrix metallopeptidase 28
chr7_-_45726974 0.31 ENSDART00000158603
si:ch211-260e23.8
si:ch211-260e23.8
chr25_+_31457309 0.29 ENSDART00000022325
parp16
poly (ADP-ribose) polymerase family, member 16
chr18_-_44323435 0.28 ENSDART00000098599
si:ch211-151h10.2
si:ch211-151h10.2
chr18_+_2203805 0.27

chr3_-_15849644 0.26 ENSDART00000160668
nme3
NME/NM23 nucleoside diphosphate kinase 3
chr5_+_26804344 0.25 ENSDART00000121886
ENSDART00000005025
hdr
hematopoietic death receptor
chr16_-_7525980 0.25 ENSDART00000017445
prdm1a
PR domain containing 1a, with ZNF domain
chr6_-_39346614 0.25 ENSDART00000104074
zgc:158846
zgc:158846
chr24_-_42037243 0.24

chr5_-_54026450 0.23 ENSDART00000159009
spag8
sperm associated antigen 8
chr9_-_30437160 0.23 ENSDART00000147241
BX936337.1
ENSDARG00000092870
chr12_-_27032151 0.23 ENSDART00000153365
BX001014.2
ENSDARG00000096750
chr15_-_18110169 0.23

chr3_+_25992836 0.22 ENSDART00000010477
hsp70.3
heat shock cognate 70-kd protein, tandem duplicate 3
chr16_-_24280209 0.22 ENSDART00000048599
rps19
ribosomal protein S19
chr16_+_51319421 0.22

chr12_+_27032862 0.21

chr7_-_25426346 0.21 ENSDART00000082620
dysf
dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)
chr2_-_28687065 0.21 ENSDART00000164657
dhcr7
7-dehydrocholesterol reductase
chr6_-_39278328 0.21 ENSDART00000148531
arhgef25b
Rho guanine nucleotide exchange factor (GEF) 25b
chr3_+_47412661 0.20 ENSDART00000155648
ube2ia
ubiquitin-conjugating enzyme E2Ia
chr9_+_21548069 0.19 ENSDART00000147619
n6amt2
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr11_-_6442836 0.19 ENSDART00000004483
zgc:162969
zgc:162969
chr16_+_54350976 0.18 ENSDART00000172622
ENSDART00000020033
xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr23_-_10692678 0.18

chr3_-_53467621 0.18 ENSDART00000032788
rdh8a
retinol dehydrogenase 8a
chr8_+_30912152 0.18 ENSDART00000171400
derl3
derlin 3
chr9_-_20562293 0.18 ENSDART00000113418
igsf3
immunoglobulin superfamily, member 3
chr23_+_13106555 0.18

chr1_+_22000499 0.17 ENSDART00000017413
zmynd10
zinc finger, MYND-type containing 10
chr10_+_39148251 0.17 ENSDART00000125986
ENSDARG00000055339
ENSDARG00000055339
chr10_+_32160464 0.17 ENSDART00000099880
wnt11r
wingless-type MMTV integration site family, member 11, related
chr12_-_308929 0.17 ENSDART00000066579
ENSDART00000171396
pts
6-pyruvoyltetrahydropterin synthase
chr8_-_53508979 0.17 ENSDART00000158789
chdh
choline dehydrogenase
chr15_-_5911817 0.16

chr15_+_11772499 0.16

chr5_+_65754237 0.16 ENSDART00000170757
kntc1
kinetochore associated 1
chr2_-_58214171 0.16 ENSDART00000169909
ENSDART00000168590
ENSDARG00000103284
ENSDARG00000103284
chr15_-_35394535 0.16 ENSDART00000144153
mff
mitochondrial fission factor
chr5_+_29071526 0.16 ENSDART00000043096
ak8
adenylate kinase 8
chr13_+_33578737 0.15 ENSDART00000161465
CABZ01087953.1
ENSDARG00000104106
chr6_-_35417797 0.15 ENSDART00000016586
rgs5a
regulator of G protein signaling 5a
chr12_+_22459371 0.15 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr19_+_27133834 0.15 ENSDART00000134455
zgc:100906
zgc:100906
chr17_+_42003279 0.15 ENSDART00000111537
kiz
kizuna centrosomal protein
chr8_-_22252973 0.14 ENSDART00000131805
nphp4
nephronophthisis 4
chr1_+_26330335 0.14 ENSDART00000102322
bnc2
basonuclin 2
KN149726v1_+_1094 0.14

chr1_+_49894685 0.14 ENSDART00000020412
pkd2
polycystic kidney disease 2
chr4_+_14728248 0.13 ENSDART00000124189
cmasa
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr23_+_25378921 0.13 ENSDART00000143291
RPL41
ribosomal protein L41
chr14_+_10984191 0.13 ENSDART00000113567
rlim
ring finger protein, LIM domain interacting
chr22_+_16282153 0.12 ENSDART00000162685
ENSDART00000105678
lrrc39
leucine rich repeat containing 39
chr23_-_7740845 0.11 ENSDART00000172451
plagl2
pleiomorphic adenoma gene-like 2
chr12_-_309047 0.11 ENSDART00000066579
ENSDART00000171396
pts
6-pyruvoyltetrahydropterin synthase
chr2_+_22708278 0.11 ENSDART00000163172
hs2st1a
heparan sulfate 2-O-sulfotransferase 1a
chr16_+_17808801 0.11 ENSDART00000149596
si:dkey-87o1.2
si:dkey-87o1.2
chr23_+_35614706 0.10 ENSDART00000123518
ENSDART00000113297
tuba1b
tubulin, alpha 1b
chr8_+_5222065 0.10 ENSDART00000035676
bnip3la
BCL2/adenovirus E1B interacting protein 3-like a
chr3_+_31047152 0.10

chr5_-_64201886 0.10 ENSDART00000145819
krt1-c5
keratin, type 1, gene c5
chr21_+_6829352 0.10 ENSDART00000146371
olfm1b
olfactomedin 1b
chr1_-_39622531 0.10

chr3_-_16569378 0.09 ENSDART00000055859
pold1
polymerase (DNA directed), delta 1, catalytic subunit
chr6_+_15635738 0.09 ENSDART00000128939
iqca1
IQ motif containing with AAA domain 1
chr5_-_33156615 0.09 ENSDART00000159058
dab2ipb
DAB2 interacting protein b
chr8_-_39788989 0.09 ENSDART00000067843
zgc:162025
zgc:162025
chr17_+_44583892 0.09 ENSDART00000156625
pgfb
placental growth factor b
chr13_-_51409167 0.08 ENSDART00000174550
CABZ01090417.1
ENSDARG00000108080
chr25_+_4909062 0.08 ENSDART00000170049
parvb
parvin, beta
chr11_+_38013238 0.07 ENSDART00000171496
CDK18
cyclin dependent kinase 18
chr14_-_3836967 0.07 ENSDART00000055817
ENSDARG00000038270
ENSDARG00000038270
chr21_+_6829161 0.07 ENSDART00000037265
olfm1b
olfactomedin 1b
chr25_-_18855316 0.07 ENSDART00000155927
si:ch211-68a17.7
si:ch211-68a17.7
chr7_+_24762755 0.07 ENSDART00000170873
sb:cb1058
sb:cb1058
chr9_-_12623451 0.06 ENSDART00000142024
tra2b
transformer 2 beta homolog
chr14_+_26424717 0.06

chr5_+_41396720 0.06 ENSDART00000097580
pigl
phosphatidylinositol glycan anchor biosynthesis, class L
chr23_+_36016450 0.06 ENSDART00000103035
hoxc6a
homeobox C6a
chr4_+_14728603 0.05 ENSDART00000131666
cmasa
cytidine monophosphate N-acetylneuraminic acid synthetase a
chr19_+_46567459 0.05 ENSDART00000164055
cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr19_-_42759951 0.05

chr17_+_50622887 0.05 ENSDART00000134126
fermt2
fermitin family member 2
KN150030v1_-_22642 0.05 ENSDART00000175410
CABZ01079802.1
ENSDARG00000106760
chr25_-_13737344 0.05

chr7_+_65824459 0.05 ENSDART00000098259
ENSDART00000051823
ENSDART00000104523
arntl1b
aryl hydrocarbon receptor nuclear translocator-like 1b
chr16_+_17808913 0.04 ENSDART00000149596
si:dkey-87o1.2
si:dkey-87o1.2
chr3_-_53467536 0.04 ENSDART00000032788
rdh8a
retinol dehydrogenase 8a
chr12_-_18997267 0.03 ENSDART00000149180
aco2
aconitase 2, mitochondrial
chr8_+_17042976 0.03 ENSDART00000023206
plk2b
polo-like kinase 2b (Drosophila)
chr10_+_37193690 0.03 ENSDART00000114909
cuedc1a
CUE domain containing 1a
chr6_+_15635696 0.02 ENSDART00000128939
iqca1
IQ motif containing with AAA domain 1
chr4_+_75574289 0.02 ENSDART00000174312
CU467646.4
ENSDARG00000099945
chr20_-_15029379 0.02 ENSDART00000152641
dnm3a
dynamin 3a
KN149711v1_-_7827 0.02 ENSDART00000171410
ENSDARG00000104905
ENSDARG00000104905
chr15_-_46439102 0.02 ENSDART00000125211
ENSDARG00000087950
ENSDARG00000087950
chr24_-_14447136 0.01

chr2_-_22708324 0.01

chr23_-_34983136 0.01

chr13_+_44720106 0.01 ENSDART00000017770
zbtb8os
zinc finger and BTB domain containing 8 opposite strand
chr10_+_11306969 0.00 ENSDART00000038888
hsdl2
hydroxysteroid dehydrogenase like 2
chr12_+_22459218 0.00 ENSDART00000171725
capgb
capping protein (actin filament), gelsolin-like b
chr19_-_10405099 0.00 ENSDART00000023571
u2af2b
U2 small nuclear RNA auxiliary factor 2b

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0003242 growth involved in heart morphogenesis(GO:0003241) cardiac chamber ballooning(GO:0003242) cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.2 GO:0002280 monocyte activation involved in immune response(GO:0002280) negative regulation of phagocytosis(GO:0050765)
0.1 0.2 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.1 GO:0032965 regulation of collagen metabolic process(GO:0010712) regulation of collagen biosynthetic process(GO:0032965) regulation of multicellular organismal metabolic process(GO:0044246) response to oscillatory fluid shear stress(GO:0097702) cellular response to oscillatory fluid shear stress(GO:0097704)
0.0 0.3 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.0 0.2 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.4 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.2 GO:0000012 single strand break repair(GO:0000012)
0.0 0.2 GO:0051155 positive regulation of striated muscle cell differentiation(GO:0051155)
0.0 0.7 GO:0039020 pronephric nephron tubule development(GO:0039020)
0.0 0.3 GO:0044243 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.2 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.2 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.0 0.2 GO:0042446 hormone biosynthetic process(GO:0042446)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491) regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000095)
0.0 0.2 GO:0042026 protein refolding(GO:0042026)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.3 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.1 GO:0002551 mast cell chemotaxis(GO:0002551) regulation of mast cell chemotaxis(GO:0060753) positive regulation of mast cell chemotaxis(GO:0060754) mast cell migration(GO:0097531)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.5 GO:0007338 single fertilization(GO:0007338)
0.0 0.3 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 0.1 GO:0097065 anterior head development(GO:0097065)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.1 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0097546 ciliary base(GO:0097546)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.2 GO:0003874 6-pyruvoyltetrahydropterin synthase activity(GO:0003874)
0.1 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.2 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.1 GO:0004394 heparan sulfate 2-O-sulfotransferase activity(GO:0004394)
0.0 0.5 GO:0043236 laminin binding(GO:0043236)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.1 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.1 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.0 0.1 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.2 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.5 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0 0.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.1 REACTOME BASE EXCISION REPAIR Genes involved in Base Excision Repair
0.0 0.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis