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Results for wt1a+wt1b

Z-value: 2.74

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Transcription factors associated with wt1a+wt1b

Gene Symbol Gene ID Gene Info
ENSDARG00000007990 WT1 transcription factor b
ENSDARG00000031420 WT1 transcription factor a

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
wt1adr10_dc_chr25_-_15117843_151178940.911.4e-06Click!
wt1bdr10_dc_chr18_-_45620179_456201920.838.3e-05Click!

Activity profile of wt1a+wt1b motif

Sorted Z-values of wt1a+wt1b motif

Network of associatons between targets according to the STRING database.

First level regulatory network of wt1a+wt1b

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_46768482 9.72 ENSDART00000015046
follistatin-like 1a
chr14_-_943860 7.35 ENSDART00000010773
acyl-CoA synthetase long-chain family member 1b
chr19_+_2013850 7.15 ENSDART00000048850
SH3-domain binding protein 5a (BTK-associated)
chr1_-_50831155 6.92 ENSDART00000152719
sprouty-related, EVH1 domain containing 2a
chr14_+_21531709 6.88 ENSDART00000144367
C-terminal binding protein 1
chr9_-_39195468 6.20 ENSDART00000014207
myosin, light chain 1, alkali; skeletal, fast
chr3_+_16115708 6.03 ENSDART00000122519
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr1_+_29054033 6.00 ENSDART00000054066
zic family member 2 (odd-paired homolog, Drosophila) b
chr3_+_32394653 5.94 ENSDART00000150897
si:ch73-367p23.2
chr8_-_53508979 5.92 ENSDART00000158789
choline dehydrogenase
chr23_+_45020761 5.86 ENSDART00000159104
ATPase, Na+/K+ transporting, beta 2a polypeptide
chr5_+_6054781 5.77 ENSDART00000060532
zgc:110796
chr14_+_41805073 5.73 ENSDART00000074362
protocadherin 18b
chr1_-_53247258 5.71 ENSDART00000007732
calpain 9
chr18_-_15404998 5.52 ENSDART00000031752
regulatory factor X, 4
chr6_-_39315024 5.25 ENSDART00000012644
keratin 4
chr16_-_46799406 5.17 ENSDART00000115244
mex-3 RNA binding family member A
chr12_+_9842842 5.08 ENSDART00000055019
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4
chr17_+_30687093 5.02 ENSDART00000179434
apolipoprotein Ba
chr13_+_25298383 4.99

chr4_-_76620869 4.95

chr1_-_416138 4.94 ENSDART00000092524
RAS p21 protein activator 3
chr16_-_53896201 4.93 ENSDART00000179533
frizzled class receptor 1
KN149909v1_+_1319 4.85

chr15_+_125263 4.84

chr14_-_46359062 4.83 ENSDART00000090844
zgc:153018
chr10_-_28949111 4.82 ENSDART00000030138
activated leukocyte cell adhesion molecule a
chr17_-_124685 4.71 ENSDART00000158825
actin, alpha, cardiac muscle 1b
chr6_+_6333766 4.63 ENSDART00000140827
B-cell CLL/lymphoma 11Ab
chr10_+_9052152 4.51 ENSDART00000139466
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2
chr13_+_22350043 4.43 ENSDART00000136863
LIM domain binding 3a
chr18_-_15405161 4.41 ENSDART00000031752
regulatory factor X, 4
chr10_+_4094568 4.35 ENSDART00000114533
meningioma 1a
chr16_-_31959111 4.34 ENSDART00000135669
RNA binding protein, fox-1 homolog (C. elegans) 1-like
chr14_+_41804998 4.33 ENSDART00000074362
protocadherin 18b
chr18_+_12207888 4.33

chr19_+_34114412 4.32 ENSDART00000162517
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr23_+_2597825 4.30 ENSDART00000159039
ENSDARG00000089986
chr12_-_954375 4.23 ENSDART00000054367
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr8_+_54171992 4.15 ENSDART00000122692
ENSDARG00000086057
chr20_-_158899 4.13 ENSDART00000131635
solute carrier family 16 (aromatic amino acid transporter), member 10
chr2_-_39710140 4.12 ENSDART00000147821
splA/ryanodine receptor domain and SOCS box containing 4a
chr3_+_49277125 4.10 ENSDART00000161724
growth arrest-specific 7a
chr6_-_22504772 4.06 ENSDART00000170039
septin 9b
chr16_+_1227270 4.02

chr4_+_1750689 3.98 ENSDART00000146779
solute carrier family 38, member 2
chr23_-_7889744 3.96 ENSDART00000164117
myelin transcription factor 1b
chr10_+_10830549 3.94 ENSDART00000101077
ENSDART00000139143
prostaglandin D2 synthase a
chr13_-_508202 3.92 ENSDART00000066080
ENSDART00000128969
slit homolog 1a (Drosophila)
chr7_-_50827308 3.91 ENSDART00000121574
collagen, type IV, alpha 6
chr6_-_2294751 3.87 ENSDART00000165223
pre-B-cell leukemia homeobox 1b
chr2_+_24649130 3.85 ENSDART00000078972
fat storage-inducing transmembrane protein 1
chr4_-_76594677 3.84 ENSDART00000049170
zgc:85975
chr3_+_14238188 3.82 ENSDART00000165452
ENSDART00000171726
transmembrane protein 56b
chr24_-_4418454 3.78 ENSDART00000066835
frizzled class receptor 8a
chr7_-_26165200 3.77 ENSDART00000123395
hairy-related 8a
chr9_-_30553051 3.74 ENSDART00000147030
synaptotagmin-like 5
chr7_-_54407681 3.69 ENSDART00000162795
cyclin D1
chr21_+_28921734 3.64 ENSDART00000166575
protein phosphatase 3, catalytic subunit, alpha isozyme
chr10_+_32617430 3.63 ENSDART00000109029
microtubule-associated protein 6a
chr19_-_32214978 3.58 ENSDART00000103640
hes-related family bHLH transcription factor with YRPW motif 1
chr7_+_73408688 3.57 ENSDART00000159745
Purkinje cell protein 4 like 1
KN149874v1_+_3991 3.55

chr14_+_241493 3.53 ENSDART00000002232
muscle segment homeobox 1a
chr3_+_37645350 3.53 ENSDART00000134524
ribosomal protein S11
chr5_+_71367929 3.51 ENSDART00000149910
c-abl oncogene 1, non-receptor tyrosine kinase
chr16_+_5377008 3.46 ENSDART00000133972
plectin b
chr20_-_9593191 3.42 ENSDART00000014168
zinc finger protein 36, C3H type-like 1b
chr3_+_5665300 3.40 ENSDART00000101807
si:ch211-106h11.3
chr11_-_32461160 3.39 ENSDART00000155592
protocadherin 17
chr9_-_33916709 3.37 ENSDART00000028225
monoamine oxidase
chr17_+_11353143 3.35 ENSDART00000013170
kinesin family member 26Ba
chr14_-_6901415 3.33 ENSDART00000167994
ENSDART00000166532
storkhead box 2b
chr16_-_22218191 3.33 ENSDART00000140175
si:dkey-71b5.3
chr13_-_31304614 3.32

chr10_+_10252074 3.32 ENSDART00000144214
SH2 domain containing 3Ca
chr19_+_31046291 3.27 ENSDART00000052124
family with sequence similarity 49, member A-like
chr17_+_8166167 3.27 ENSDART00000169900
CDC42 binding protein kinase alpha (DMPK-like) a
chr11_+_10557530 3.24 ENSDART00000132365
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a
chr25_-_340711 3.23 ENSDART00000178866
ENSDARG00000107546
chr25_+_4918339 3.21 ENSDART00000153980
parvin, beta
chr18_+_5456221 3.21

chr19_-_19290260 3.21

chr19_+_32183937 3.21 ENSDART00000147474
stathmin 2b
chr6_+_39373026 3.20 ENSDART00000157165
si:dkey-195m11.8
chr11_+_6809190 3.18 ENSDART00000104289
RAB3A, member RAS oncogene family, b
chr5_+_42312784 3.16 ENSDART00000039973
RUN and FYVE domain containing 3
chr23_-_30858769 3.16 ENSDART00000131285
myelin transcription factor 1a
chr17_+_1610578 3.16 ENSDART00000082101
protein phosphatase 2, regulatory subunit B', gamma a
chr19_-_617298 3.15 ENSDART00000171387
cytochrome P450, family 51
chr2_-_58111727 3.14 ENSDART00000004431
ENSDART00000166845
ENSDART00000163999
erythrocyte membrane protein band 4.1-like 3b
chr13_+_13550656 3.14 ENSDART00000057825
complement factor D (adipsin)
KN149874v1_+_3898 3.13

chr20_+_13998066 3.12 ENSDART00000007744
solute carrier family 30 (zinc transporter), member 1a
chr8_+_20125687 3.11 ENSDART00000124809
acyl-CoA synthetase bubblegum family member 2
chr11_+_11735899 3.09 ENSDART00000003891
junction plakoglobin a
chr23_-_624534 3.08 ENSDART00000132175
neural adhesion molecule L1.1
chr4_-_22751641 3.08 ENSDART00000066903
ENSDART00000130072
ENSDART00000123369
lysine (K)-specific methyltransferase 2E
chr25_+_24152717 3.07 ENSDART00000064646
transmembrane protein 86A
chr5_-_71505131 3.06 ENSDART00000037691
T-box 5a
chr16_-_41994015 3.06

chr5_-_55843553 3.05 ENSDART00000024207
T-box 2a
chr12_+_689413 3.00 ENSDART00000174804
ATP-binding cassette, sub-family C (CFTR/MRP), member 3
chr7_-_54407461 2.91 ENSDART00000162795
cyclin D1
chr17_-_31678247 2.91 ENSDART00000143090
lin-52 DREAM MuvB core complex component
chr2_+_33399405 2.90 ENSDART00000137207
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr2_-_44330405 2.90 ENSDART00000111246
cell adhesion molecule 3
chr21_-_39013447 2.88 ENSDART00000114885
aldehyde dehydrogenase 3 family, member A2b
chr12_-_47699958 2.88 ENSDART00000171932
ENSDART00000168165
ENSDART00000161985
hematopoietically expressed homeobox
chr14_-_2682064 2.85 ENSDART00000161677
si:dkey-201i24.6
chr17_+_24596687 2.84 ENSDART00000064739
ribosomal protein L13a
KN150131v1_+_59098 2.84 ENSDART00000175590
ENSDARG00000106550
chr12_-_268910 2.84 ENSDART00000045071
forkhead box K2
KN149987v1_-_29629 2.83 ENSDART00000159555
ENSDART00000168161
ENSDARG00000103311
chr15_-_47264693 2.82

chr16_-_29229687 2.78 ENSDART00000132589
myocyte enhancer factor 2d
chr8_-_15071283 2.75

chr2_-_3317258 2.75 ENSDART00000167944
wingless-type MMTV integration site family, member 3A
chr15_-_14616083 2.74 ENSDART00000171169
numb homolog (Drosophila)-like
chr5_-_13826859 2.73 ENSDART00000137355
tet methylcytosine dioxygenase 3
chr10_-_1690605 2.72 ENSDART00000137620
si:ch73-46j18.5
chr14_-_46359248 2.71 ENSDART00000090844
zgc:153018
chr15_-_1225595 2.69

chr23_-_2573949 2.66 ENSDART00000123322
snail family zinc finger 1b
chr10_+_38568464 2.63 ENSDART00000109752
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a
chr11_-_2107054 2.61 ENSDART00000173031
homeobox C6b
chr12_+_41016238 2.61 ENSDART00000170976
kinesin family member 5B, b
chr8_+_8127635 2.59 ENSDART00000147940
plexin B3
chr2_+_43619752 2.57 ENSDART00000142078
ENSDART00000098265
ENSDART00000098267
neuropilin 1b
chr12_-_35590747 2.55

chr23_+_28804842 2.52 ENSDART00000047378
somatostatin 3
chr20_+_23392782 2.52

chr1_-_38189932 2.51 ENSDART00000136102
vascular endothelial growth factor c
chr23_-_7283514 2.51 ENSDART00000156369
ENSDARG00000096997
chr10_+_1812271 2.50

chr8_-_52952226 2.47 ENSDART00000168185
nuclear receptor subfamily 6, group A, member 1a
chr19_+_1814994 2.45

chr11_-_232269 2.44 ENSDART00000172818
si:ch1073-456m8.1
chr15_-_19314712 2.44 ENSDART00000092705
immunoglobulin superfamily, member 9Ba
chr2_-_44429891 2.42 ENSDART00000163040
ENSDART00000056372
ENSDART00000109251
ENSDART00000166923
ENSDART00000132682
myelin protein zero
chr2_-_42784609 2.40

chr3_+_16115532 2.40

chr1_-_50513645 2.39 ENSDART00000047851
jagged 1a
chr16_+_25845432 2.39

chr24_+_3296536 2.39 ENSDART00000147468
3-hydroxybutyrate dehydrogenase, type 1
chr12_-_48278273 2.37

chr5_+_8843643 2.37 ENSDART00000149417
ENSDART00000061616
T-cell acute lymphocytic leukemia 2
chr24_-_3273409 2.36

chr8_-_2054323 2.34 ENSDART00000123804
clathrin, heavy chain-like 1
chr9_-_24602136 2.31 ENSDART00000135897
transmembrane protein with EGF-like and two follistatin-like domains 2a
chr14_-_9216303 2.31 ENSDART00000054689
atonal bHLH transcription factor 8
chr10_-_1645 2.29

chr23_+_27985224 2.29 ENSDART00000171859
ENSDARG00000100606
chr2_-_9848848 2.28 ENSDART00000056901
zgc:153615
chr4_-_72603830 2.25 ENSDART00000168547
si:cabz01071912.2
chr19_+_12066023 2.23 ENSDART00000130537
sperm associated antigen 1a
chr1_-_50513873 2.22 ENSDART00000137172
jagged 1a
chr10_+_10393377 2.20 ENSDART00000109432
cerebral endothelial cell adhesion molecule
chr5_+_26925238 2.16 ENSDART00000051491
secreted frizzled-related protein 1a
chr24_+_38783264 2.16 ENSDART00000154214
si:ch73-70c5.1
chr14_+_23986703 2.14 ENSDART00000079164
kelch-like family member 3
chr18_-_15498798 2.13 ENSDART00000109410
endonuclease, polyU-specific C
chr1_-_13547500 2.10 ENSDART00000044896
calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2
chr1_+_54231447 2.10 ENSDART00000145652
golgin A7 family, member Ba
chr8_+_6533379 2.09 ENSDART00000138135
V-set and immunoglobulin domain containing 8b
chr15_-_47264619 2.07

chr14_-_12531063 2.07 ENSDART00000165004
ENSDART00000043180
glutamate receptor, ionotropic, AMPA 3b
chr21_+_13764828 2.07 ENSDART00000171306
syntaxin binding protein 1a
chr23_+_26995808 2.06

chr7_+_31567166 2.05 ENSDART00000099785
ENSDART00000122506
myosin binding protein C, cardiac
chr5_+_11340748 2.05 ENSDART00000159248
tescalcin a
chr16_+_5778398 2.03 ENSDART00000011166
ENSDART00000126445
zgc:158689
chr20_+_26408687 2.03

chr3_-_5318289 2.02 ENSDART00000137105
myosin, heavy chain 9b, non-muscle
chr5_+_22465722 2.01 ENSDART00000145477
ENSDART00000089992
high mobility group nucleosomal binding domain 7
chr10_+_34372205 2.00 ENSDART00000110121
StAR-related lipid transfer (START) domain containing 13a
chr5_+_36014029 1.99 ENSDART00000150574
neuro-oncological ventral antigen 1
chr3_+_32360862 1.98 ENSDART00000151329
transient receptor potential cation channel, subfamily M, member 4a
chr20_+_26981663 1.97 ENSDART00000077769
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr16_-_543957 1.96 ENSDART00000016303
iroquois homeobox 2a
chr21_+_11046459 1.95 ENSDART00000169024
alanine--glyoxylate aminotransferase 2
chr18_-_15498733 1.95 ENSDART00000109410
endonuclease, polyU-specific C
KN149978v1_-_10669 1.95 ENSDART00000175723
ENSDARG00000105971
chr6_+_55091896 1.93

chr12_-_308929 1.93 ENSDART00000066579
ENSDART00000171396
6-pyruvoyltetrahydropterin synthase
chr22_-_62082 1.92 ENSDART00000166010
ENSDART00000125700
mitochondrial ribosomal protein L20
chr17_+_53224434 1.92 ENSDART00000166517
ankyrin repeat and SOCS box containing 2b
chr23_+_33457343 1.92 ENSDART00000114423
Rap guanine nucleotide exchange factor (GEF) 3
chr8_+_54003190 1.91

chr3_-_34417082 1.90 ENSDART00000166623
septin 9a
chr4_-_76594399 1.90 ENSDART00000049170
zgc:85975
chr16_+_21099550 1.89

chr10_+_45499009 1.89 ENSDART00000166085
peptidylprolyl isomerase Ab (cyclophilin A)
chr17_-_43475725 1.88 ENSDART00000155313
heat shock protein 4 like
chr13_-_508050 1.87 ENSDART00000066080
ENSDART00000128969
slit homolog 1a (Drosophila)
chr8_-_46500948 1.87 ENSDART00000168384
sulfotransferase family 1, cytosolic sulfotransferase 1
chr25_-_36886647 1.86 ENSDART00000160688
proteasome subunit alpha 1
chr5_+_26925392 1.86 ENSDART00000051491
secreted frizzled-related protein 1a
chr21_-_14534576 1.86 ENSDART00000089967
ENSDART00000132142
calcium channel, voltage-dependent, N type, alpha 1B subunit, b
chr25_+_35269590 1.85 ENSDART00000034737
copine VIII

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 9.9 GO:0021910 smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021910)
1.7 6.9 GO:0010799 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
1.4 4.1 GO:0032616 interleukin-13 production(GO:0032616) regulation of interleukin-13 production(GO:0032656)
1.3 3.8 GO:0060898 eye field cell fate commitment involved in camera-type eye formation(GO:0060898)
1.1 4.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
1.1 5.4 GO:1902751 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971) mitotic G1 DNA damage checkpoint(GO:0031571) positive regulation of cell cycle G2/M phase transition(GO:1902751)
1.0 3.1 GO:1990359 detoxification of zinc ion(GO:0010312) stress response to zinc ion(GO:1990359)
1.0 3.1 GO:0003294 atrial ventricular junction remodeling(GO:0003294)
1.0 3.0 GO:0072068 distal convoluted tubule development(GO:0072025) late distal convoluted tubule development(GO:0072068)
1.0 4.0 GO:0003322 pancreatic A cell development(GO:0003322)
0.9 6.0 GO:0021627 olfactory nerve development(GO:0021553) olfactory nerve morphogenesis(GO:0021627) olfactory nerve formation(GO:0021628)
0.8 5.9 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.8 2.5 GO:0060855 venous endothelial cell migration involved in lymph vessel development(GO:0060855)
0.8 3.2 GO:0099558 maintenance of presynaptic active zone structure(GO:0048790) maintenance of synapse structure(GO:0099558)
0.8 6.0 GO:0033278 cell proliferation in midbrain(GO:0033278)
0.7 5.2 GO:0009712 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.7 2.9 GO:0099565 chemical synaptic transmission, postsynaptic(GO:0099565)
0.7 4.2 GO:0006621 protein retention in ER lumen(GO:0006621)
0.7 2.0 GO:0002706 regulation of lymphocyte mediated immunity(GO:0002706)
0.6 7.1 GO:0061099 negative regulation of peptidyl-tyrosine phosphorylation(GO:0050732) negative regulation of protein tyrosine kinase activity(GO:0061099)
0.6 2.3 GO:2001014 regulation of skeletal muscle cell differentiation(GO:2001014)
0.6 2.3 GO:0035332 positive regulation of hippo signaling(GO:0035332)
0.6 4.0 GO:0006868 glutamine transport(GO:0006868)
0.6 2.8 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
0.5 1.6 GO:1904035 epithelial cell apoptotic process(GO:1904019) regulation of epithelial cell apoptotic process(GO:1904035)
0.5 1.6 GO:2000253 negative regulation of lipid transport(GO:0032369) endocrine process(GO:0050886) positive regulation of feeding behavior(GO:2000253)
0.5 2.0 GO:0003210 cardiac atrium formation(GO:0003210)
0.4 3.6 GO:0070650 actin filament bundle distribution(GO:0070650)
0.4 1.7 GO:0051414 response to cortisol(GO:0051414) cellular response to cortisol stimulus(GO:0071387)
0.4 4.3 GO:0033138 positive regulation of peptidyl-serine phosphorylation(GO:0033138)
0.4 2.6 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.4 2.1 GO:0072017 distal tubule development(GO:0072017)
0.4 6.0 GO:0045773 positive regulation of axon extension(GO:0045773)
0.4 9.7 GO:0060034 notochord cell differentiation(GO:0060034)
0.4 5.0 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.4 3.1 GO:0002159 desmosome assembly(GO:0002159)
0.4 4.9 GO:0043363 nucleate erythrocyte differentiation(GO:0043363)
0.4 6.3 GO:0002250 adaptive immune response(GO:0002250)
0.4 2.6 GO:1902287 semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.3 6.2 GO:0071711 basement membrane organization(GO:0071711)
0.3 5.9 GO:0036376 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.3 3.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.3 3.1 GO:0006956 complement activation(GO:0006956)
0.3 2.5 GO:0048796 swim bladder maturation(GO:0048796) swim bladder inflation(GO:0048798)
0.3 1.8 GO:0007343 egg activation(GO:0007343)
0.3 3.1 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.3 0.8 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.3 1.6 GO:0006703 estrogen biosynthetic process(GO:0006703) estrogen metabolic process(GO:0008210)
0.3 1.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.3 7.3 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.3 5.4 GO:0030878 thyroid gland development(GO:0030878)
0.3 1.5 GO:0061075 positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868)
0.2 2.7 GO:0021794 thalamus development(GO:0021794)
0.2 0.9 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.2 3.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.9 GO:0008592 regulation of Toll signaling pathway(GO:0008592)
0.2 1.1 GO:0010991 SMAD protein complex assembly(GO:0007183) regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.2 0.6 GO:0046166 methylglyoxal biosynthetic process(GO:0019242) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 2.5 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.2 2.7 GO:0003260 cardioblast migration(GO:0003260) cardioblast migration to the midline involved in heart field formation(GO:0060975)
0.2 1.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.2 1.1 GO:0019427 acetate metabolic process(GO:0006083) acetyl-CoA biosynthetic process from acetate(GO:0019427)
0.2 5.4 GO:0007586 digestion(GO:0007586)
0.2 3.2 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.2 1.5 GO:0009134 nucleoside diphosphate catabolic process(GO:0009134)
0.2 1.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2 3.9 GO:0050773 regulation of dendrite development(GO:0050773)
0.2 1.5 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
0.2 9.6 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.2 0.5 GO:0098773 skin epidermis development(GO:0098773)
0.2 2.6 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.2 1.8 GO:1900077 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.1 0.4 GO:0002934 desmosome organization(GO:0002934)
0.1 7.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 2.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 3.5 GO:0043049 otic placode formation(GO:0043049)
0.1 1.6 GO:0030316 osteoclast differentiation(GO:0030316)
0.1 3.4 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 2.6 GO:0030199 collagen fibril organization(GO:0030199)
0.1 2.2 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 4.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 14.7 GO:0007519 skeletal muscle tissue development(GO:0007519)
0.1 2.0 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 0.4 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.1 2.0 GO:0035778 pronephric nephron tubule epithelial cell differentiation(GO:0035778) cell differentiation involved in pronephros development(GO:0039014)
0.1 2.7 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.1 3.2 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 0.6 GO:0006085 acetyl-CoA biosynthetic process(GO:0006085)
0.1 1.0 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.1 2.4 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.1 1.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 3.3 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.1 3.7 GO:0030917 midbrain-hindbrain boundary development(GO:0030917)
0.1 0.8 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.1 0.8 GO:1904357 negative regulation of telomere maintenance via telomerase(GO:0032211) negative regulation of telomere maintenance via telomere lengthening(GO:1904357)
0.1 10.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.3 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 7.4 GO:0010721 negative regulation of cell development(GO:0010721)
0.1 0.9 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 1.9 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.4 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.1 1.1 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.1 3.2 GO:0001878 response to yeast(GO:0001878)
0.1 4.5 GO:0007229 integrin-mediated signaling pathway(GO:0007229)
0.1 1.9 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.8 GO:0016486 peptide hormone processing(GO:0016486)
0.1 0.7 GO:0072102 glomerulus morphogenesis(GO:0072102)
0.1 4.9 GO:0046777 protein autophosphorylation(GO:0046777)
0.1 1.8 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 2.9 GO:0006081 cellular aldehyde metabolic process(GO:0006081)
0.1 0.5 GO:0015961 diadenosine polyphosphate metabolic process(GO:0015959) diadenosine polyphosphate catabolic process(GO:0015961)
0.1 2.1 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.3 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.1 1.9 GO:0071277 cellular response to calcium ion(GO:0071277)
0.1 3.7 GO:0061640 cytoskeleton-dependent cytokinesis(GO:0061640)
0.1 2.0 GO:0010951 negative regulation of endopeptidase activity(GO:0010951)
0.1 0.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.1 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 1.9 GO:0070509 calcium ion import(GO:0070509)
0.0 1.2 GO:0048854 brain morphogenesis(GO:0048854)
0.0 1.4 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 2.4 GO:0001945 lymph vessel development(GO:0001945)
0.0 2.1 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.5 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 1.3 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.0 0.6 GO:0051289 protein homotetramerization(GO:0051289)
0.0 3.3 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 1.7 GO:0007254 JNK cascade(GO:0007254)
0.0 1.3 GO:0060395 SMAD protein signal transduction(GO:0060395)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588)
0.0 2.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 1.7 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.9 GO:0051260 protein homooligomerization(GO:0051260)
0.0 0.3 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 3.4 GO:0060548 negative regulation of cell death(GO:0060548)
0.0 1.2 GO:0022900 electron transport chain(GO:0022900)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 1.9 GO:0006898 receptor-mediated endocytosis(GO:0006898)
0.0 6.0 GO:0007420 brain development(GO:0007420)
0.0 3.0 GO:0050767 regulation of neurogenesis(GO:0050767)
0.0 0.4 GO:0045104 intermediate filament-based process(GO:0045103) intermediate filament cytoskeleton organization(GO:0045104)
0.0 1.7 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.7 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.2 GO:0043551 regulation of lipid kinase activity(GO:0043550) regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 1.9 GO:0043067 regulation of programmed cell death(GO:0043067)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.0 GO:0042627 chylomicron(GO:0042627)
1.0 3.9 GO:0098644 complex of collagen trimers(GO:0098644)
0.7 5.9 GO:0090533 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.6 2.9 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.5 3.6 GO:0005955 calcineurin complex(GO:0005955)
0.5 7.9 GO:0005801 cis-Golgi network(GO:0005801)
0.4 1.7 GO:0016586 RSC complex(GO:0016586)
0.4 1.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.4 2.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.4 4.7 GO:0005869 dynactin complex(GO:0005869)
0.4 1.4 GO:0070062 extracellular exosome(GO:0070062)
0.4 2.5 GO:0071439 clathrin complex(GO:0071439)
0.3 3.5 GO:0030056 hemidesmosome(GO:0030056)
0.3 3.5 GO:0043209 myelin sheath(GO:0043209)
0.3 0.8 GO:1990879 CST complex(GO:1990879)
0.3 2.9 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.2 2.3 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 1.2 GO:1990246 uniplex complex(GO:1990246)
0.2 3.8 GO:0030057 desmosome(GO:0030057)
0.2 4.0 GO:0045095 keratin filament(GO:0045095)
0.2 1.9 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 3.7 GO:0031105 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.2 4.5 GO:0008305 integrin complex(GO:0008305)
0.1 7.7 GO:0042641 actomyosin(GO:0042641)
0.1 6.9 GO:0016459 myosin complex(GO:0016459)
0.1 5.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.5 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.5 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 4.0 GO:0030426 growth cone(GO:0030426)
0.1 4.6 GO:0030018 Z disc(GO:0030018)
0.1 0.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.8 GO:0005902 microvillus(GO:0005902)
0.1 1.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 3.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 2.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891) calcium channel complex(GO:0034704)
0.1 4.5 GO:0005871 kinesin complex(GO:0005871)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.1 9.5 GO:0030424 axon(GO:0030424)
0.1 2.8 GO:0022626 cytosolic ribosome(GO:0022626)
0.1 0.4 GO:0014704 intercalated disc(GO:0014704)
0.1 4.1 GO:0005884 actin filament(GO:0005884)
0.0 42.7 GO:0005576 extracellular region(GO:0005576)
0.0 22.8 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 5.5 GO:0099503 secretory vesicle(GO:0099503)
0.0 1.5 GO:0030658 transport vesicle membrane(GO:0030658)
0.0 3.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 2.3 GO:0016607 nuclear speck(GO:0016607)
0.0 1.2 GO:0030425 dendrite(GO:0030425)
0.0 3.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.0 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.3 GO:0005840 ribosome(GO:0005840)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0008131 primary amine oxidase activity(GO:0008131)
1.0 3.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.8 4.1 GO:0072349 modified amino acid transmembrane transporter activity(GO:0072349)
0.8 4.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.8 3.1 GO:0016803 ether hydrolase activity(GO:0016803)
0.7 7.3 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.7 5.0 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750) lipoprotein particle receptor binding(GO:0070325)
0.7 6.0 GO:0048495 Roundabout binding(GO:0048495)
0.6 1.7 GO:0030548 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.6 2.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.5 6.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.5 3.6 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.5 1.4 GO:0004953 icosanoid receptor activity(GO:0004953)
0.5 1.4 GO:0000829 inositol heptakisphosphate kinase activity(GO:0000829) diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.4 4.0 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.4 2.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.4 4.2 GO:0016405 CoA-ligase activity(GO:0016405)
0.4 3.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.4 2.9 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.4 1.6 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.4 3.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 7.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.4 1.8 GO:0015157 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.3 5.9 GO:0001671 ATPase activator activity(GO:0001671)
0.3 5.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.3 5.2 GO:0017154 semaphorin receptor activity(GO:0017154)
0.3 2.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 3.5 GO:0030506 ankyrin binding(GO:0030506)
0.3 3.3 GO:0005158 insulin receptor binding(GO:0005158)
0.3 5.4 GO:0005112 Notch binding(GO:0005112)
0.3 2.1 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.3 0.9 GO:0003874 6-pyruvoyltetrahydropterin synthase activity(GO:0003874)
0.3 0.8 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.3 1.1 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.3 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.3 1.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.3 7.1 GO:0004860 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.2 2.0 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 0.9 GO:0030274 LIM domain binding(GO:0030274)
0.2 4.4 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.2 0.6 GO:0004807 triose-phosphate isomerase activity(GO:0004807) methylglyoxal synthase activity(GO:0008929)
0.2 1.2 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.2 1.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 0.5 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.2 0.7 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.5 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.2 4.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 3.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 2.0 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.2 0.8 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 1.5 GO:0004382 guanosine-diphosphatase activity(GO:0004382) uridine-diphosphatase activity(GO:0045134)
0.1 3.2 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 2.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.4 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.1 4.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.2 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828)
0.1 2.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 7.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 4.2 GO:0005048 signal sequence binding(GO:0005048)
0.1 7.3 GO:0051287 NAD binding(GO:0051287)
0.1 0.8 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 3.1 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 2.1 GO:0005518 collagen binding(GO:0005518)
0.1 5.5 GO:0019843 rRNA binding(GO:0019843)
0.1 2.0 GO:0008483 transaminase activity(GO:0008483)
0.1 3.9 GO:0005109 frizzled binding(GO:0005109)
0.1 1.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 5.9 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.1 3.2 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 2.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.5 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.1 2.1 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 5.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 0.6 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.1 1.8 GO:0035497 cAMP response element binding(GO:0035497)
0.1 9.3 GO:0003774 motor activity(GO:0003774)
0.1 1.3 GO:0070411 I-SMAD binding(GO:0070411)
0.1 1.3 GO:0030165 calcium-transporting ATPase activity(GO:0005388) PDZ domain binding(GO:0030165)
0.1 1.7 GO:0042562 hormone binding(GO:0042562)
0.1 1.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.1 0.7 GO:0015026 coreceptor activity(GO:0015026)
0.1 1.1 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 4.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 12.3 GO:0042802 identical protein binding(GO:0042802)
0.1 1.7 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 2.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 4.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 25.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.4 GO:0030295 kinase activator activity(GO:0019209) protein kinase activator activity(GO:0030295)
0.0 1.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 3.0 GO:0043492 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) ATPase activity, coupled to transmembrane movement of substances(GO:0042626) ATPase activity, coupled to movement of substances(GO:0043492)
0.0 45.1 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 7.7 GO:0015631 tubulin binding(GO:0015631)
0.0 1.8 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 4.2 GO:0019901 protein kinase binding(GO:0019901)
0.0 0.7 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 1.2 GO:0030215 semaphorin receptor binding(GO:0030215) chemorepellent activity(GO:0045499)
0.0 0.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 5.9 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 3.2 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 9.5 GO:0003779 actin binding(GO:0003779)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 4.5 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 1.7 GO:0101005 thiol-dependent ubiquitin-specific protease activity(GO:0004843) thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 2.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 4.3 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 1.0 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.0 1.6 GO:0015267 channel activity(GO:0015267) passive transmembrane transporter activity(GO:0022803)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.5 5.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.5 3.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.3 10.8 PID ATM PATHWAY ATM pathway
0.2 6.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 1.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 5.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 1.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 3.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 3.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 3.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 4.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 2.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 3.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.0 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.5 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 4.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.8 3.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.7 2.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.6 2.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.5 2.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.5 5.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 4.0 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.4 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 2.5 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.3 3.0 REACTOME BILE ACID AND BILE SALT METABOLISM Genes involved in Bile acid and bile salt metabolism
0.3 6.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.3 2.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.3 9.2 REACTOME MYOGENESIS Genes involved in Myogenesis
0.3 3.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.3 2.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.2 3.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.2 5.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.2 4.9 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.2 7.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 0.9 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 0.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 3.9 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 2.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.7 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 3.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 0.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 5.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.1 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 5.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.1 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.9 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 1.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions