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Results for ybx1

Z-value: 1.01

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Transcription factors associated with ybx1

Gene Symbol Gene ID Gene Info
ybx1
ENSDARG00000004757 Y box binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ybx1dr10_dc_chr8_-_47161379_471616780.765.8e-04Click!

Activity profile of ybx1 motif

Sorted Z-values of ybx1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ybx1

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr4_-_2615160 4.83 ENSDART00000140760
e2f7
E2F transcription factor 7
chr10_+_39141022 3.61 ENSDART00000158245
si:ch73-1a9.3
si:ch73-1a9.3
chr4_+_29209923 3.51 ENSDART00000168709
ENSDARG00000104041
ENSDARG00000104041
chr10_+_39140943 2.25 ENSDART00000158245
si:ch73-1a9.3
si:ch73-1a9.3
chr1_+_23385409 2.22 ENSDART00000014608
mab21l2
mab-21-like 2
chr19_+_12315359 2.14 ENSDART00000149221
grhl2b
grainyhead-like transcription factor 2b
chr4_-_16556116 2.11 ENSDART00000033188
btg1
B-cell translocation gene 1, anti-proliferative
chr1_+_50277442 1.90 ENSDART00000150420
otx1a
orthodenticle homeobox 1a
chr16_+_4825019 1.85 ENSDART00000167665
LIN28A
lin-28 homolog A
chr21_+_5781882 1.70 ENSDART00000091331
prodha
proline dehydrogenase (oxidase) 1a
chr18_+_62936 1.67 ENSDART00000052638
slc27a2a
solute carrier family 27 (fatty acid transporter), member 2a
KN150670v1_-_72156 1.66

chr14_-_40454194 1.66 ENSDART00000166621
ef1
E74-like factor 1 (ets domain transcription factor)
chr14_-_11765407 1.64 ENSDART00000165581
tmsb1
thymosin beta 1
chr16_+_1338291 1.62 ENSDART00000149299
cers2b
ceramide synthase 2b
chr11_-_30105047 1.60 ENSDART00000030794
tmem169a
transmembrane protein 169a
chr6_+_56163589 1.55 ENSDART00000150219
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr6_-_50705420 1.52 ENSDART00000074100
osgn1
oxidative stress induced growth inhibitor 1
chr21_-_4842528 1.45 ENSDART00000097796
rnf165a
ring finger protein 165a
chr21_+_19034242 1.42 ENSDART00000123309
nkx6.1
NK6 homeobox 1
chr24_-_39884167 1.40 ENSDART00000087441
GFOD1
glucose-fructose oxidoreductase domain containing 1
chr5_+_69383382 1.38 ENSDART00000165570
rgs3a
regulator of G protein signaling 3a
chr11_+_34788205 1.34 ENSDART00000124800
fam212aa
family with sequence similarity 212, member Aa
chr18_+_22617072 1.29 ENSDART00000128965
bcar1
breast cancer anti-estrogen resistance 1
chr3_-_6078015 1.28 ENSDART00000165715
BX284638.1
ENSDARG00000098850
chr13_-_2259405 1.27 ENSDART00000166456
elovl5
ELOVL fatty acid elongase 5
chr10_+_9325719 1.26 ENSDART00000064968
rasgef1bb
RasGEF domain family, member 1Bb
chr19_+_32579358 1.26 ENSDART00000021798
fabp11a
fatty acid binding protein 11a
chr16_+_46728964 1.24 ENSDART00000163571
rab25b
RAB25, member RAS oncogene family b
chr10_+_10830549 1.23 ENSDART00000101077
ENSDART00000139143
ptgdsa
prostaglandin D2 synthase a
chr19_+_12315183 1.23 ENSDART00000149221
grhl2b
grainyhead-like transcription factor 2b
chr3_+_21925465 1.21

chr11_-_15162109 1.15 ENSDART00000124968
rpn2
ribophorin II
chr23_+_44951868 1.15

chr13_-_30515486 1.15 ENSDART00000139607
zcchc24
zinc finger, CCHC domain containing 24
chr15_+_1187249 1.13 ENSDART00000152638
ENSDART00000152466
mlf1
myeloid leukemia factor 1
chr6_+_251026 1.09 ENSDART00000042970
atf4a
activating transcription factor 4a
chr4_+_30012767 1.09 ENSDART00000150383
znf1128
zinc finger protein 1128
chr18_+_5456221 1.07

chr19_-_1905372 1.04 ENSDART00000029646
rplp1
ribosomal protein, large, P1
chr25_+_34515221 1.04 ENSDART00000046218
flnca
filamin C, gamma a (actin binding protein 280)
chr6_+_3549861 1.01 ENSDART00000170781
phospho2
phosphatase, orphan 2
chr23_+_44817648 0.99 ENSDART00000143688
dlg4b
discs, large homolog 4b (Drosophila)
chr23_+_6861489 0.99 ENSDART00000092131
si:ch211-117c9.5
si:ch211-117c9.5
chr23_-_41756325 0.98 ENSDART00000146808
si:ch73-184c24.1
si:ch73-184c24.1
chr6_+_48138737 0.97

chr25_-_3521512 0.97 ENSDART00000171863
ENSDART00000166363
si:ch211-272n13.3
si:ch211-272n13.3
chr7_+_5784612 0.95 ENSDART00000114327
zgc:112234
zgc:112234
chr9_+_13149212 0.93 ENSDART00000141005
fam117bb
family with sequence similarity 117, member Bb
chr20_-_53133918 0.91 ENSDART00000166508
fdft1
farnesyl-diphosphate farnesyltransferase 1
chr20_-_53560663 0.89 ENSDART00000146001
wasf1
WAS protein family, member 1
chr25_+_35855292 0.89 ENSDART00000152801
ankrd27
ankyrin repeat domain 27 (VPS9 domain)
chr21_-_26369545 0.83 ENSDART00000077200
eif4ebp3
eukaryotic translation initiation factor 4E binding protein 3
chr16_+_52779257 0.82

chr17_-_21179064 0.82

chr19_-_15951003 0.82 ENSDART00000133059
cited4a
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4a
chr3_+_2013046 0.80 ENSDART00000112979
sox10
SRY (sex determining region Y)-box 10
chr22_+_10172134 0.80 ENSDART00000132641
pdhb
pyruvate dehydrogenase (lipoamide) beta
chr20_+_16843502 0.78 ENSDART00000050308
calm1b
calmodulin 1b
chr18_-_49121584 0.78 ENSDART00000174157
ENSDARG00000099137
ENSDARG00000099137
chr25_+_34546629 0.74 ENSDART00000133379
hist2h3c
histone cluster 2, H3c
chr16_+_11260802 0.74 ENSDART00000140674
cicb
capicua transcriptional repressor b
chr19_+_48499602 0.74

chr8_-_4451417 0.73 ENSDART00000141915
si:ch211-166a6.5
si:ch211-166a6.5
chr19_-_34508557 0.73 ENSDART00000160495
si:dkey-184p18.2
si:dkey-184p18.2
chr1_-_11707288 0.71 ENSDART00000134708
sclt1
sodium channel and clathrin linker 1
chr19_-_10962536 0.70 ENSDART00000160438
psmd4a
proteasome 26S subunit, non-ATPase 4a
chr20_+_54464026 0.68 ENSDART00000158810
ENSDART00000161631
ENSDART00000172631
ENSDART00000168924
fkbp3
FK506 binding protein 3
chr1_+_25378105 0.68 ENSDART00000059264
mxd4
MAX dimerization protein 4
chr11_-_40255633 0.67 ENSDART00000172819
miip
migration and invasion inhibitory protein
chr6_+_2849460 0.67

chr20_+_54463948 0.66 ENSDART00000158810
ENSDART00000161631
ENSDART00000172631
ENSDART00000168924
fkbp3
FK506 binding protein 3
chr14_-_9274939 0.64

chr15_+_41878670 0.63 ENSDART00000137434
pxylp1
2-phosphoxylose phosphatase 1
chr9_+_24891584 0.61

chr21_-_797123 0.61 ENSDART00000144766
nars
asparaginyl-tRNA synthetase
chr22_+_38220826 0.60 ENSDART00000010537
cp
ceruloplasmin
chr15_-_20795531 0.60 ENSDART00000114464
tpst1
tyrosylprotein sulfotransferase 1
chr4_+_13451169 0.59 ENSDART00000172552
dyrk2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
chr20_-_47576935 0.59 ENSDART00000067776
rab10
RAB10, member RAS oncogene family
chr25_-_8475902 0.58 ENSDART00000176751
CU929451.3
ENSDARG00000107886
chr3_-_58488929 0.58 ENSDART00000042386
unm_sa1261
un-named sa1261
chr7_-_56533829 0.57 ENSDART00000010322
senp8
SUMO/sentrin peptidase family member, NEDD8 specific
chr6_-_48095609 0.57 ENSDART00000137458
slc2a1b
solute carrier family 2 (facilitated glucose transporter), member 1b
chr1_-_18110990 0.55 ENSDART00000020970
pgm2
phosphoglucomutase 2
chr13_+_4312466 0.55 ENSDART00000156323
tb
T, brachyury homolog b
chr6_-_34974860 0.55 ENSDART00000113097
hsd17b7
hydroxysteroid (17-beta) dehydrogenase 7
chr25_-_13737344 0.55

chr17_-_52435859 0.55

chr9_-_41072329 0.55 ENSDART00000066424
pofut2
protein O-fucosyltransferase 2
chr11_-_18442094 0.54 ENSDART00000159380
zmynd8
zinc finger, MYND-type containing 8
chr25_-_3521317 0.53 ENSDART00000171863
ENSDART00000166363
si:ch211-272n13.3
si:ch211-272n13.3
chr4_+_45204456 0.53 ENSDART00000158744
BX927336.3
ENSDARG00000102848
chr6_+_53349584 0.50 ENSDART00000167079
si:ch211-161c3.5
si:ch211-161c3.5
chr6_+_10636497 0.50 ENSDART00000041858
mtx2
metaxin 2
chr5_+_4906729 0.50 ENSDART00000139553
mapkap1
mitogen-activated protein kinase associated protein 1
chr8_-_1154004 0.49 ENSDART00000149969
ENSDART00000016800
znf367
zinc finger protein 367
chr4_-_16555765 0.49 ENSDART00000033188
btg1
B-cell translocation gene 1, anti-proliferative
chr23_+_14834670 0.49 ENSDART00000143675
si:rp71-79p20.2
si:rp71-79p20.2
chr2_-_39709905 0.48 ENSDART00000147821
spsb4a
splA/ryanodine receptor domain and SOCS box containing 4a
chr11_+_26152136 0.48

chr12_-_36191048 0.47 ENSDART00000177986
cep131
centrosomal protein 131
chr3_+_62081343 0.47 ENSDART00000058719
znf1124
zinc finger protein 1124
chr8_+_47909655 0.47

chr19_-_791149 0.46 ENSDART00000151782
ENSDART00000037515
msto1
misato 1, mitochondrial distribution and morphology regulator
chr1_-_54294303 0.45 ENSDART00000140016
khsrp
KH-type splicing regulatory protein
chr10_+_36082726 0.45 ENSDART00000165386
hmgb1a
high mobility group box 1a
chr25_+_35762694 0.44 ENSDART00000136456
ENSDART00000175090
CR354435.8
zgc:173552
Histone H3.2
zgc:173552
chr23_-_5429419 0.44 ENSDART00000159105
CR936540.3
ENSDARG00000101435
chr14_+_16508093 0.44 ENSDART00000161201
limch1b
LIM and calponin homology domains 1b
chr7_+_73601671 0.42 ENSDART00000163075
zgc:173552
zgc:173552
chr25_+_34557335 0.42 ENSDART00000089844
zgc:113983
zgc:113983
chr5_+_2839985 0.41

chr14_-_16171165 0.41 ENSDART00000089021
canx
calnexin
chr16_+_38335706 0.40

chr19_+_24340673 0.40

chr24_-_41356844 0.39 ENSDART00000121592
ENSDART00000019975
ENSDART00000166034
acvr2b
activin A receptor, type IIB
chr4_+_36180573 0.39 ENSDART00000161159
ENSDARG00000102102
ENSDARG00000102102
chr7_+_67510360 0.38 ENSDART00000172015
cyb5b
cytochrome b5 type B
chr22_+_37688585 0.38 ENSDART00000174664
ENSDART00000178200
FO704589.1
ENSDARG00000108910
chr7_-_24119645 0.38 ENSDART00000141769
ptgr1
prostaglandin reductase 1
chr16_-_52761159 0.38 ENSDART00000111869
ubr5
ubiquitin protein ligase E3 component n-recognin 5
chr24_+_36478896 0.37

chr1_-_29919280 0.37 ENSDART00000152175
MZT1
mitotic spindle organizing protein 1
chr4_-_74789596 0.37 ENSDART00000174356
ENSDART00000174313
si:ch73-158p21.3
si:ch73-158p21.3
chr16_+_5411816 0.37

chr19_-_30975279 0.37 ENSDART00000171006
hpcal4
hippocalcin like 4
chr5_+_35839198 0.37 ENSDART00000102973
ENSDART00000103020
eda
ectodysplasin A
chr8_+_8889274 0.36 ENSDART00000142075
pim2
Pim-2 proto-oncogene, serine/threonine kinase
chr16_+_49423377 0.36 ENSDART00000015694
rab5ab
RAB5A, member RAS oncogene family, b
chr21_-_26453406 0.36 ENSDART00000009889
zgc:110540
zgc:110540
chr4_-_9195261 0.36 ENSDART00000080943
hcfc2
host cell factor C2
chr7_+_5783441 0.35 ENSDART00000167099
CU459186.5
Histone H3.2
chr10_+_6009364 0.35 ENSDART00000163680
hmgcs1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr6_-_25962268 0.35 ENSDART00000076997
lmo4b
LIM domain only 4b
chr9_+_41072345 0.34 ENSDART00000141548
hibch
3-hydroxyisobutyryl-CoA hydrolase
chr7_-_6330257 0.33 ENSDART00000173138
zgc:112234
zgc:112234
chr8_-_34077790 0.33

chr7_-_6308104 0.32 ENSDART00000173010
zgc:112234
zgc:112234
chr9_-_2416300 0.31

chr2_+_29265967 0.31 ENSDART00000099157
cdh18a
cadherin 18, type 2a
chr25_-_35037680 0.30 ENSDART00000097651
si:ch211-87j1.4
si:ch211-87j1.4
chr17_-_31204651 0.29 ENSDART00000137834
pcmtl
l-isoaspartyl protein carboxyl methyltransferase, like
chr19_+_43434941 0.29 ENSDART00000038230
snrnp40
small nuclear ribonucleoprotein 40 (U5)
chr11_+_43334742 0.28

chr10_+_1610794 0.28 ENSDART00000060946
sgsm1b
small G protein signaling modulator 1b
chr13_-_30515304 0.27 ENSDART00000139607
zcchc24
zinc finger, CCHC domain containing 24
chr22_-_16154562 0.26 ENSDART00000090390
vcam1b
vascular cell adhesion molecule 1b
chr3_-_60985683 0.26 ENSDART00000133091
pvalb5
parvalbumin 5
chr2_-_56531858 0.26 ENSDART00000113589
gpx4b
glutathione peroxidase 4b
chr12_+_46944395 0.26 ENSDART00000149032
oat
ornithine aminotransferase
chr3_+_15245529 0.26

chr22_-_3954917 0.25 ENSDART00000162523
kdm4b
lysine (K)-specific demethylase 4B
chr6_+_52350428 0.25 ENSDART00000151612
si:ch211-239j9.1
si:ch211-239j9.1
KN149926v1_+_1959 0.25

chr11_-_42263721 0.25 ENSDART00000130573
atp6ap1la
ATPase, H+ transporting, lysosomal accessory protein 1-like a
chr18_-_26912259 0.23 ENSDART00000147735
si:dkey-24l11.2
si:dkey-24l11.2
chr25_-_34557204 0.23

chr23_-_2027166 0.22 ENSDART00000127443
prdm5
PR domain containing 5
chr19_-_43434820 0.21 ENSDART00000122135
zcchc17
zinc finger, CCHC domain containing 17
chr8_+_16702533 0.21 ENSDART00000100698
ercc8
excision repair cross-complementation group 8
chr22_+_36934624 0.21 ENSDART00000158293
mccc1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr4_-_5238656 0.20 ENSDART00000050221
atp6v1e1b
ATPase, H+ transporting, lysosomal, V1 subunit E1b
chr18_+_5637588 0.20

chr21_+_5597476 0.20 ENSDART00000161235
ENSDART00000170456
shroom3
shroom family member 3
chr5_+_23582396 0.20 ENSDART00000051549
ENSDART00000135934
tp53
tumor protein p53
chr7_+_26278650 0.18 ENSDART00000141353
tnk1
tyrosine kinase, non-receptor, 1
chr17_-_43296680 0.18 ENSDART00000176637
EML5
echinoderm microtubule associated protein like 5
chr13_+_42476309 0.18 ENSDART00000133388
mlh1
mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
chr15_-_19314712 0.18 ENSDART00000092705
igsf9ba
immunoglobulin superfamily, member 9Ba
chr16_+_68014 0.17 ENSDART00000159652
sox4b
SRY (sex determining region Y)-box 4b
chr4_-_18660286 0.17 ENSDART00000178638
pparaa
peroxisome proliferator-activated receptor alpha a
chr19_+_43237078 0.16 ENSDART00000108775
ubp1
upstream binding protein 1 (LBP-1a)
chr3_-_47828170 0.16

chr3_+_62051743 0.16 ENSDART00000168063
zgc:173575
zgc:173575
chr25_-_1549206 0.16

chr3_-_32409303 0.16 ENSDART00000151476
rcn3
reticulocalbin 3, EF-hand calcium binding domain
chr10_+_7744503 0.14 ENSDART00000099089
ggcx
gamma-glutamyl carboxylase
chr25_-_6262259 0.13 ENSDART00000083539
sin3aa
SIN3 transcription regulator family member Aa
chr22_-_11618612 0.13 ENSDART00000109596
dpp4
dipeptidyl-peptidase 4
chr11_+_31061296 0.13 ENSDART00000088093
sipa1l2
signal-induced proliferation-associated 1 like 2
chr6_-_50588444 0.13 ENSDART00000151500
mtss1
metastasis suppressor 1
chr10_-_44505679 0.12

chr20_+_37963275 0.12 ENSDART00000153190
vash2
vasohibin 2
chr4_+_295110 0.12 ENSDART00000067489
si:ch211-51e12.7
si:ch211-51e12.7
chr11_-_18442169 0.12 ENSDART00000171183
zmynd8
zinc finger, MYND-type containing 8
chr17_+_31204729 0.11 ENSDART00000155580
ccdc32
coiled-coil domain containing 32
chr5_+_25538112 0.11 ENSDART00000010041
dhfr
dihydrofolate reductase
chr19_-_34508527 0.11 ENSDART00000160495
si:dkey-184p18.2
si:dkey-184p18.2
chr11_-_15162471 0.10 ENSDART00000010684
rpn2
ribophorin II
chr20_-_40589999 0.10 ENSDART00000075070
hsf2
heat shock transcription factor 2
chr9_-_43015354 0.10

chr12_-_1018688 0.09 ENSDART00000054353
ENSDARG00000037357
ENSDARG00000037357
chr4_+_75484112 0.09 ENSDART00000174393
si:dkey-240n22.8
si:dkey-240n22.8
chr21_+_5597536 0.09 ENSDART00000161235
ENSDART00000170456
shroom3
shroom family member 3
chr20_+_31312234 0.09

chr12_-_36303384 0.09 ENSDART00000168538
oxld1
oxidoreductase-like domain containing 1
chr5_+_61136704 0.08 ENSDART00000113508
hnrnpul1l
heterogeneous nuclear ribonucleoprotein U-like 1 like
chr7_-_73590802 0.08 ENSDART00000167855
FP236812.8
Histone H2B 1/2
chr9_+_34412811 0.08 ENSDART00000028617
mpc2
mitochondrial pyruvate carrier 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0042023 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.6 1.7 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.3 1.0 GO:0072578 neurotransmitter-gated ion channel clustering(GO:0072578)
0.3 2.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.3 1.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.3 0.8 GO:0006086 acetyl-CoA biosynthetic process from pyruvate(GO:0006086)
0.2 1.4 GO:0008591 regulation of Wnt signaling pathway, calcium modulating pathway(GO:0008591)
0.2 3.0 GO:0060561 apoptotic process involved in morphogenesis(GO:0060561)
0.2 0.6 GO:0042762 regulation of sulfur metabolic process(GO:0042762)
0.2 0.6 GO:0006477 protein sulfation(GO:0006477) peptidyl-tyrosine sulfation(GO:0006478)
0.2 1.0 GO:0090527 actin filament reorganization(GO:0090527)
0.2 1.3 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.1 0.7 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 1.4 GO:0003310 pancreatic A cell differentiation(GO:0003310)
0.1 0.4 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 1.1 GO:0070309 lens fiber cell development(GO:0070307) lens fiber cell morphogenesis(GO:0070309)
0.1 0.4 GO:0048169 regulation of long-term neuronal synaptic plasticity(GO:0048169)
0.1 0.5 GO:0048311 mitochondrion distribution(GO:0048311)
0.1 0.8 GO:0021988 olfactory bulb development(GO:0021772) olfactory lobe development(GO:0021988)
0.1 0.9 GO:0045022 early endosome to late endosome transport(GO:0045022) vesicle-mediated transport between endosomal compartments(GO:0098927)
0.1 0.5 GO:0090317 negative regulation of intracellular protein transport(GO:0090317)
0.1 1.6 GO:0014036 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.1 1.0 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.1 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.3 GO:0006574 valine catabolic process(GO:0006574)
0.1 0.4 GO:0048041 cell-substrate adherens junction assembly(GO:0007045) focal adhesion assembly(GO:0048041) regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109)
0.1 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.4 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) regulation of protein K63-linked ubiquitination(GO:1900044) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) regulation of protein polyubiquitination(GO:1902914) negative regulation of protein polyubiquitination(GO:1902915)
0.1 0.5 GO:0006004 fucose metabolic process(GO:0006004)
0.1 0.3 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 2.6 GO:0008285 negative regulation of cell proliferation(GO:0008285)
0.0 0.6 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 0.7 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 1.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.2 GO:0010888 negative regulation of cholesterol storage(GO:0010887) negative regulation of lipid storage(GO:0010888)
0.0 0.5 GO:0009409 response to cold(GO:0009409)
0.0 0.4 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.0 1.2 GO:0018107 peptidyl-threonine phosphorylation(GO:0018107)
0.0 1.5 GO:0030308 negative regulation of cell growth(GO:0030308)
0.0 0.1 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0042476 odontogenesis(GO:0042476)
0.0 1.0 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.2 GO:2000050 regulation of non-canonical Wnt signaling pathway(GO:2000050)
0.0 0.1 GO:0051754 meiotic sister chromatid segregation(GO:0045144) meiotic sister chromatid cohesion(GO:0051177) meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.1 GO:1902624 positive regulation of neutrophil migration(GO:1902624)
0.0 0.3 GO:0072015 neural tube closure(GO:0001843) glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.3 0.8 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 1.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.4 GO:0016460 myosin II complex(GO:0016460)
0.1 0.4 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.5 GO:0001401 mitochondrial sorting and assembly machinery complex(GO:0001401)
0.1 1.0 GO:0098839 postsynaptic density membrane(GO:0098839) postsynaptic specialization membrane(GO:0099634)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 0.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0033181 plasma membrane proton-transporting V-type ATPase complex(GO:0033181)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 5.8 GO:0000785 chromatin(GO:0000785)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 1.1 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.8 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.3 0.9 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2 0.6 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 0.8 GO:0004738 pyruvate dehydrogenase activity(GO:0004738)
0.2 1.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 5.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.6 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.6 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 1.7 GO:0015245 long-chain fatty acid transporter activity(GO:0005324) fatty acid transporter activity(GO:0015245)
0.1 0.4 GO:0032038 myosin head/neck binding(GO:0032028) myosin II head/neck binding(GO:0032034) myosin II heavy chain binding(GO:0032038)
0.1 0.5 GO:0046922 peptide-O-fucosyltransferase activity(GO:0046922)
0.1 0.9 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.6 GO:0005355 glucose transmembrane transporter activity(GO:0005355) monosaccharide transmembrane transporter activity(GO:0015145) hexose transmembrane transporter activity(GO:0015149)
0.1 0.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.1 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 1.6 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.1 0.4 GO:0005123 death receptor binding(GO:0005123)
0.1 0.2 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
0.0 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0035925 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.6 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 1.3 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.5 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0016289 CoA hydrolase activity(GO:0016289)
0.0 0.4 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 2.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.0 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 0.6 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 1.5 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.4 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.1 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.0 1.0 GO:0015293 symporter activity(GO:0015293)
0.0 0.4 GO:0031593 polyubiquitin binding(GO:0031593)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 5.6 PID E2F PATHWAY E2F transcription factor network
0.1 1.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.3 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.7 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 1.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.6 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.1 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 2.3 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP