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Results for yy1a+yy1b
Z-value: 1.63
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Transcription factors associated with yy1a+yy1b
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| yy1a | dr10_dc_chr17_-_30846176_30846335 | -0.56 | 2.4e-02 | Click! |
| yy1b | dr10_dc_chr20_-_54645287_54645324 | -0.39 | 1.4e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of yy1a+yy1b
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_18118467 Show fit | 2.64 |
ENSDART00000142026
|
si:dkey-167i21.2 |
|
| chr14_-_35552296 Show fit | 2.50 |
ENSDART00000052648
|
transmembrane protein 144b |
|
| chr12_+_22448972 Show fit | 1.97 |
|
|
|
| chr3_-_31942015 Show fit | 1.85 |
|
|
|
| chr14_-_41101660 Show fit | 1.71 |
ENSDART00000003170
|
MID1 interacting protein 1, like |
|
| chr21_-_13593659 Show fit | 1.65 |
ENSDART00000065817
|
POU domain, class 5, transcription factor 3 |
|
| chr12_-_16386055 Show fit | 1.60 |
ENSDART00000152750
|
polycomb group ring finger 5b |
|
| chr18_+_284210 Show fit | 1.53 |
ENSDART00000158040
|
La ribonucleoprotein domain family, member 6 |
|
| chr2_+_10349452 Show fit | 1.46 |
ENSDART00000153678
|
profilin 2 like |
|
| chr5_+_24016742 Show fit | 1.45 |
ENSDART00000144560
|
DGCR8 microprocessor complex subunit |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 9.0 | GO:0036353 | histone H2A-K119 monoubiquitination(GO:0036353) |
| 0.0 | 5.4 | GO:0018105 | peptidyl-serine phosphorylation(GO:0018105) |
| 0.6 | 4.2 | GO:0010867 | regulation of triglyceride biosynthetic process(GO:0010866) positive regulation of triglyceride biosynthetic process(GO:0010867) |
| 0.1 | 3.7 | GO:0016573 | histone acetylation(GO:0016573) |
| 0.6 | 3.2 | GO:0060965 | negative regulation of posttranscriptional gene silencing(GO:0060149) negative regulation of gene silencing by miRNA(GO:0060965) negative regulation of gene silencing by RNA(GO:0060967) |
| 0.1 | 2.7 | GO:0071166 | ribonucleoprotein complex localization(GO:0071166) |
| 0.3 | 2.5 | GO:0034219 | carbohydrate transmembrane transport(GO:0034219) |
| 0.1 | 2.3 | GO:1990126 | retrograde transport, endosome to plasma membrane(GO:1990126) |
| 0.4 | 2.1 | GO:0038095 | Fc-epsilon receptor signaling pathway(GO:0038095) |
| 0.2 | 2.1 | GO:0060876 | semicircular canal formation(GO:0060876) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 9.0 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.1 | 6.2 | GO:0000786 | nucleosome(GO:0000786) |
| 0.3 | 4.3 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.6 | 4.2 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.1 | 3.8 | GO:0000123 | histone acetyltransferase complex(GO:0000123) |
| 0.0 | 2.7 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.1 | 2.5 | GO:1902555 | endoribonuclease complex(GO:1902555) |
| 0.2 | 2.4 | GO:0070775 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.0 | 2.3 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.4 | 2.2 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.4 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
| 0.1 | 6.0 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 5.5 | GO:0003712 | transcription factor activity, transcription factor binding(GO:0000989) transcription cofactor activity(GO:0003712) |
| 0.2 | 4.9 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.4 | 4.5 | GO:0008494 | translation activator activity(GO:0008494) |
| 0.0 | 4.4 | GO:0000287 | magnesium ion binding(GO:0000287) |
| 0.1 | 3.5 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 2.9 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 2.5 | GO:1901476 | carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476) |
| 0.0 | 2.4 | GO:0003713 | transcription coactivator activity(GO:0003713) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.9 | PID KIT PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.1 | 2.1 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 1.7 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.2 | 1.6 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.0 | 1.6 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 1.4 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.1 | 1.1 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 1.0 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 1.0 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 0.9 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.2 | REACTOME SIGNALING BY SCF KIT | Genes involved in Signaling by SCF-KIT |
| 0.1 | 1.9 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.1 | 1.9 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.1 | 1.6 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.1 | 1.6 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 1.6 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.0 | 1.5 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.2 | 1.4 | REACTOME SIGNALING BY NOTCH4 | Genes involved in Signaling by NOTCH4 |
| 0.0 | 1.4 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 1.3 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |