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Results for zbtb12.1+zbtb12.2

Z-value: 0.70

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Transcription factors associated with zbtb12.1+zbtb12.2

Gene Symbol Gene ID Gene Info
zbtb12.2
ENSDARG00000070658 zinc finger and BTB domain containing 12, tandem duplicate 2
zbtb12.1
ENSDARG00000103949 zinc finger and BTB domain containing 12, tandem duplicate 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb12.2dr10_dc_chr19_-_27379989_27380198-0.504.6e-02Click!

Activity profile of zbtb12.1+zbtb12.2 motif

Sorted Z-values of zbtb12.1+zbtb12.2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb12.1+zbtb12.2

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr2_-_17443607 2.06 ENSDART00000136207
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr15_+_38397772 1.90 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr19_-_27995593 1.76 ENSDART00000142263
si:dkeyp-46h3.3
si:dkeyp-46h3.3
chr2_-_17443642 1.74 ENSDART00000136207
pif1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr24_-_7928026 1.42 ENSDART00000145815
txndc5
thioredoxin domain containing 5
KN150339v1_-_39357 1.32 ENSDART00000169638
wu:fa19b12
wu:fa19b12
chr8_-_38284959 1.23 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr21_+_20350152 1.20 ENSDART00000144366
si:dkey-30k6.5
si:dkey-30k6.5
chr14_-_6220150 1.18 ENSDART00000125058
nipsnap3a
nipsnap homolog 3A (C. elegans)
chr10_-_25383262 1.14 ENSDART00000166348
cct8
chaperonin containing TCP1, subunit 8 (theta)
chr19_+_21209328 1.13 ENSDART00000142463
txnl4a
thioredoxin-like 4A
chr12_+_9811557 1.10 ENSDART00000110458
fam117ab
family with sequence similarity 117, member Ab
chr21_-_28700679 1.00 ENSDART00000128237
ENSDART00000124826
nrg2a
neuregulin 2a
chr6_-_1613740 0.99 ENSDART00000156305
trim107
tripartite motif containing 107
chr5_-_66145078 0.94 ENSDART00000041441
stip1
stress-induced phosphoprotein 1
chr13_-_7904111 0.92

chr14_+_47368995 0.91 ENSDART00000060577
tmem33
transmembrane protein 33
chr19_+_27056002 0.89 ENSDART00000175951
ints3
integrator complex subunit 3
chr22_-_9832436 0.87

chr22_+_1283662 0.84 ENSDART00000124161
si:ch73-138e16.5
si:ch73-138e16.5
chr20_-_5992604 0.83 ENSDART00000170468
cep128
centrosomal protein 128
chr7_-_59851075 0.77 ENSDART00000128363
cct7
chaperonin containing TCP1, subunit 7 (eta)
chr17_-_12095843 0.73 ENSDART00000155545
ahctf1
AT hook containing transcription factor 1
chr6_-_1613915 0.73 ENSDART00000112118
trim107
tripartite motif containing 107
chr17_-_12095723 0.72 ENSDART00000115321
ahctf1
AT hook containing transcription factor 1
chr19_+_27055869 0.72 ENSDART00000067793
ENSDART00000124755
ints3
integrator complex subunit 3
chr17_+_49540985 0.70

chr8_+_13757024 0.70

chr5_-_45244910 0.69

chr16_-_26505960 0.61 ENSDART00000144462
BX571757.1
ENSDARG00000088497
chr8_+_13757180 0.61

chr2_+_52225622 0.61 ENSDART00000170353
ENSDARG00000103108
ENSDARG00000103108
chr14_+_47368951 0.60 ENSDART00000060577
tmem33
transmembrane protein 33
chr15_+_38397897 0.59 ENSDART00000142403
si:dkey-24p1.6
si:dkey-24p1.6
chr22_-_9832520 0.59

chr17_-_52239876 0.57

chr21_-_13575544 0.57 ENSDART00000146717
clic3
chloride intracellular channel 3
chr21_-_28700622 0.57 ENSDART00000098696
nrg2a
neuregulin 2a
chr6_-_1613994 0.55 ENSDART00000112118
trim107
tripartite motif containing 107
chr4_-_4603205 0.54 ENSDART00000130601
CABZ01020840.1
ENSDARG00000090401
chr10_+_29963102 0.53 ENSDART00000168898
hspa8
heat shock protein 8
chr6_-_2768437 0.50

chr20_-_29630048 0.49 ENSDART00000049224
taf1b
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
chr18_+_8444064 0.49 ENSDART00000171974
prpf18
PRP18 pre-mRNA processing factor 18 homolog (yeast)
chr16_-_10946422 0.48 ENSDART00000036891
rabac1
Rab acceptor 1 (prenylated)
chr16_-_32865452 0.47

chr7_+_28753073 0.46 ENSDART00000076425
cog4
component of oligomeric golgi complex 4
chr17_-_35290338 0.46 ENSDART00000005784
itgb1bp1
integrin beta 1 binding protein 1
chr3_-_36235222 0.43 ENSDART00000028883
gna13b
guanine nucleotide binding protein (G protein), alpha 13b
chr10_-_22176478 0.43

chr21_-_43176006 0.38 ENSDART00000148630
hspa4a
heat shock protein 4a
chr19_+_9066225 0.38 ENSDART00000018973
scamp3
secretory carrier membrane protein 3
chr19_+_21208954 0.37 ENSDART00000014774
txnl4a
thioredoxin-like 4A
chr8_-_38285034 0.36 ENSDART00000125920
pdlim2
PDZ and LIM domain 2 (mystique)
chr16_-_42225498 0.36 ENSDART00000084715
alkbh8
alkB homolog 8, tRNA methyltransferase
chr3_+_42667814 0.36 ENSDART00000172425
zfand2a
zinc finger, AN1-type domain 2A
chr7_+_28753102 0.33 ENSDART00000076425
cog4
component of oligomeric golgi complex 4
chr24_-_7928168 0.32 ENSDART00000145815
txndc5
thioredoxin domain containing 5
chr20_+_38555185 0.29 ENSDART00000020153
adck3
aarF domain containing kinase 3
chr8_+_44629016 0.29

chr16_-_48488178 0.27 ENSDART00000005927
rad21a
RAD21 cohesin complex component a
chr10_-_25383076 0.24 ENSDART00000009477
cct8
chaperonin containing TCP1, subunit 8 (theta)
chr2_+_52225552 0.23 ENSDART00000170353
ENSDARG00000103108
ENSDARG00000103108
KN150650v1_+_861 0.22

chr17_-_27402265 0.22 ENSDART00000127043
ythdf2
YTH N(6)-methyladenosine RNA binding protein 2
chr12_-_17013870 0.22

chr9_-_45096523 0.22 ENSDART00000110697
dnajc10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr10_-_15090551 0.21 ENSDART00000038401
ENSDART00000155674
si:ch211-95j8.2
si:ch211-95j8.2
chr1_-_51086075 0.20 ENSDART00000045894
rnaseh2a
ribonuclease H2, subunit A
KN150650v1_+_738 0.18

chr7_-_59851104 0.15 ENSDART00000128363
cct7
chaperonin containing TCP1, subunit 7 (eta)
chr18_-_21921898 0.14 ENSDART00000132381
edc4
enhancer of mRNA decapping 4
chr12_-_31619559 0.13

chr3_+_40265548 0.09 ENSDART00000103486
tnrc18
trinucleotide repeat containing 18
chr7_-_56465497 0.08 ENSDART00000020967
csnk2a2a
casein kinase 2, alpha prime polypeptide a
chr19_+_43526327 0.07

chr6_-_20308805 0.06 ENSDART00000083038
nprl2
NPR2-like, GATOR1 complex subunit
chr6_+_34406796 0.06

chr16_-_10946309 0.05 ENSDART00000049148
rabac1
Rab acceptor 1 (prenylated)
chr6_+_40525610 0.05 ENSDART00000033819
prkcda
protein kinase C, delta a
chr5_-_42350607 0.02 ENSDART00000149868
grsf1
G-rich RNA sequence binding factor 1
chr19_+_43526408 0.02

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0051292 pore complex assembly(GO:0046931) nuclear pore complex assembly(GO:0051292)
0.3 3.8 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.3 1.4 GO:0035095 behavioral response to nicotine(GO:0035095)
0.3 1.5 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.3 0.8 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.3 1.6 GO:0098773 ventricular trabecula myocardium morphogenesis(GO:0003222) skin epidermis development(GO:0098773)
0.1 0.5 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 0.5 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.4 GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation(GO:0003262)
0.1 1.6 GO:0044818 mitotic G2/M transition checkpoint(GO:0044818)
0.1 0.5 GO:1902946 protein localization to early endosome(GO:1902946)
0.1 0.2 GO:1903429 regulation of cell maturation(GO:1903429)
0.1 1.7 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 0.3 GO:0003173 ventriculo bulbo valve development(GO:0003173)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.4 GO:0002098 tRNA wobble uridine modification(GO:0002098)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0070876 SOSS complex(GO:0070876)
0.2 2.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 0.5 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.2 0.5 GO:0071020 post-spliceosomal complex(GO:0071020)
0.1 1.5 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.3 GO:0034990 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.1 0.4 GO:0031526 brush border membrane(GO:0031526)
0.1 3.8 GO:0005657 replication fork(GO:0005657)
0.1 0.8 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.6 GO:0031941 filamentous actin(GO:0031941)
0.0 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 1.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0001772 immunological synapse(GO:0001772)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.8 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.1 0.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 1.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 1.6 GO:0051371 muscle alpha-actinin binding(GO:0051371) alpha-actinin binding(GO:0051393)
0.1 0.4 GO:0050780 dopamine receptor binding(GO:0050780)
0.1 0.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.5 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046) core promoter binding(GO:0001047)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 2.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 1.6 GO:0008083 growth factor activity(GO:0008083)
0.0 0.6 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 1.8 GO:0030246 carbohydrate binding(GO:0030246)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 PID TELOMERASE PATHWAY Regulation of Telomerase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 2.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.9 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions