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Results for zbtb14

Z-value: 2.26

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Transcription factors associated with zbtb14

Gene Symbol Gene ID Gene Info
zbtb14
ENSDARG00000098273 zinc finger and BTB domain containing 14

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb14dr10_dc_chr24_-_42053682_42053815-0.322.3e-01Click!

Activity profile of zbtb14 motif

Sorted Z-values of zbtb14 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb14

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr24_+_32261533 7.60 ENSDART00000003745
vim
vimentin
chr1_+_53286155 5.77 ENSDART00000139625
acta1a
actin, alpha 1a, skeletal muscle
chr4_+_5733160 5.67 ENSDART00000110243
pou3f2a
POU class 3 homeobox 2a
chr21_+_105327 5.14 ENSDART00000007672
dmgdh
dimethylglycine dehydrogenase
chr18_+_62936 4.90 ENSDART00000052638
slc27a2a
solute carrier family 27 (fatty acid transporter), member 2a
chr23_-_20332076 4.73 ENSDART00000147326
lamb2
laminin, beta 2 (laminin S)
chr4_-_73485204 4.52 ENSDART00000122898
phf21b
PHD finger protein 21B
chr11_+_15796506 4.37 ENSDART00000081098
draxin
dorsal inhibitory axon guidance protein
chr7_+_67227810 4.22 ENSDART00000163840
gcshb
glycine cleavage system protein H (aminomethyl carrier), b
chr2_-_58737903 4.05

chr1_-_55554518 3.90 ENSDART00000019573
zgc:65894
zgc:65894
chr10_-_27261937 3.81

chr2_+_42874975 3.66 ENSDART00000075392
basp1
brain abundant, membrane attached signal protein 1
chr4_+_22959458 3.61 ENSDART00000036531
gnai1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr20_-_26632676 3.61 ENSDART00000131994
mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr12_-_7572970 3.55 ENSDART00000158095
slc16a9b
solute carrier family 16, member 9b
chr10_-_13814731 3.52 ENSDART00000145103
cntfr
ciliary neurotrophic factor receptor
chr19_+_3713027 3.49 ENSDART00000125673
nedd9
neural precursor cell expressed, developmentally down-regulated 9
chr4_+_9027862 3.45 ENSDART00000102893
aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr22_-_13018196 3.30 ENSDART00000028787
ahr1b
aryl hydrocarbon receptor 1b
chr23_-_39956151 3.28 ENSDART00000115330
ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14C
chr23_+_45876483 3.19 ENSDART00000169521
ENSDART00000162915
dclk2b
doublecortin-like kinase 2b
chr15_+_37039861 3.09 ENSDART00000172664
kirrel3l
kin of IRRE like 3 like
chr4_+_10065500 3.07 ENSDART00000026492
flncb
filamin C, gamma b (actin binding protein 280)
chr19_+_26065401 3.02 ENSDART00000146947
tac1
tachykinin 1
chr1_-_37990863 3.02 ENSDART00000132402
gpm6ab
glycoprotein M6Ab
chr20_-_35343242 2.96 ENSDART00000113294
fzd3a
frizzled class receptor 3a
chr22_-_3661536 2.95 ENSDART00000153634
FP565432.1
ENSDARG00000097145
chr23_+_45020761 2.89 ENSDART00000159104
atp1b2a
ATPase, Na+/K+ transporting, beta 2a polypeptide
chr14_-_25279835 2.88 ENSDART00000163669
cplx2
complexin 2
chr10_-_37131530 2.88 ENSDART00000132023
myo18aa
myosin XVIIIAa
chr2_+_26523457 2.84 ENSDART00000024662
plppr3a
phospholipid phosphatase related 3a
chr16_+_3090170 2.83 ENSDART00000110395
limd1a
LIM domains containing 1a
chr17_-_756401 2.82 ENSDART00000157622
zbtb42
zinc finger and BTB domain containing 42
chr14_+_14759314 2.79 ENSDART00000167075
nkx1.2lb
NK1 transcription factor related 2-like,b
chr5_+_49103778 2.79 ENSDART00000155405
CR751602.2
ENSDARG00000098045
chr2_-_30340646 2.79 ENSDART00000099078
jph1b
junctophilin 1b
chr9_-_14533551 2.77 ENSDART00000056103
nrp2b
neuropilin 2b
chr4_-_73485028 2.74 ENSDART00000122898
phf21b
PHD finger protein 21B
chr8_-_387126 2.73

chr5_+_62987426 2.70 ENSDART00000178937
dnm1b
dynamin 1b
chr13_-_5440923 2.69 ENSDART00000102576
meis1b
Meis homeobox 1 b
chr6_+_56157608 2.68 ENSDART00000149665
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr7_-_14135850 2.62 ENSDART00000161442
CU467822.1
ENSDARG00000101584
chr3_+_17594555 2.55 ENSDART00000055890
znf385c
zinc finger protein 385C
chr20_+_54512601 2.52 ENSDART00000169386
faua
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed a
chr3_+_13114740 2.50 ENSDART00000162724
ENSDARG00000074231
ENSDARG00000074231
chr20_-_40553998 2.50 ENSDART00000075092
pkib
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr24_-_38928988 2.49 ENSDART00000063231
nog2
noggin 2
chr23_+_45876447 2.47 ENSDART00000169521
ENSDART00000162915
dclk2b
doublecortin-like kinase 2b
chr12_-_9400344 2.46 ENSDART00000003932
erbb2
erb-b2 receptor tyrosine kinase 2
chr11_-_1108157 2.46

chr18_+_45680282 2.45 ENSDART00000109948
qser1
glutamine and serine rich 1
chr5_-_43896815 2.45 ENSDART00000110076
gas1a
growth arrest-specific 1a
chr17_+_3842688 2.43 ENSDART00000170822
tmx4
thioredoxin-related transmembrane protein 4
chr22_-_21289850 2.42 ENSDART00000135388
cks2
CDC28 protein kinase regulatory subunit 2
chr17_+_53224434 2.41 ENSDART00000166517
asb2b
ankyrin repeat and SOCS box containing 2b
chr5_-_43896757 2.40 ENSDART00000110076
gas1a
growth arrest-specific 1a
chr3_-_21149752 2.39 ENSDART00000003939
syngr1a
synaptogyrin 1a
chr22_+_223797 2.36

chr1_-_22144014 2.36 ENSDART00000043556
ldb2b
LIM domain binding 2b
chr5_-_15774816 2.35 ENSDART00000090684
kremen1
kringle containing transmembrane protein 1
chr19_-_5338129 2.34 ENSDART00000081951
stx1b
syntaxin 1B
chr25_-_35760878 2.32 ENSDART00000121786
hist1h4l
histone 1, H4, like
chr23_+_2193582 2.31 ENSDART00000106336
cpeb2
cytoplasmic polyadenylation element binding protein 2
chr13_+_1741432 2.31 ENSDART00000161162
bmp5
bone morphogenetic protein 5
chr25_-_18044103 2.31 ENSDART00000113581
kitlga
kit ligand a
chr13_-_31339870 2.30 ENSDART00000076574
rtn1a
reticulon 1a
KN150001v1_+_14939 2.29

chr4_+_3970874 2.27 ENSDART00000049194
gpr37b
G protein-coupled receptor 37b
chr25_-_20283541 2.26 ENSDART00000142665
kctd15a
potassium channel tetramerization domain containing 15a
chr13_+_1741474 2.26 ENSDART00000161162
bmp5
bone morphogenetic protein 5
chr25_+_34997593 2.25 ENSDART00000058443
fibina
fin bud initiation factor a
chr24_-_35811390 2.25 ENSDART00000167990
mapre2
microtubule-associated protein, RP/EB family, member 2
chr2_+_49683715 2.23 ENSDART00000122742
ENSDART00000160783
rorcb
RAR-related orphan receptor C b
chr16_+_28819826 2.20 ENSDART00000103340
s100v1
S100 calcium binding protein V1
chr23_-_44460486 2.16 ENSDART00000149115
zgc:158659
zgc:158659
chr16_+_32605735 2.16 ENSDART00000093250
pou3f2b
POU class 3 homeobox 2b
chr4_+_14972481 2.15 ENSDART00000005985
smo
smoothened, frizzled class receptor
chr8_-_50899451 2.13 ENSDART00000053750
acsl2
acyl-CoA synthetase long-chain family member 2
chr14_-_46219646 2.13 ENSDART00000110191
shisa3
shisa family member 3
chr12_-_48493654 2.09 ENSDART00000162603
ndufb8
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8
chr4_+_14972708 2.08 ENSDART00000005985
smo
smoothened, frizzled class receptor
chr11_-_37322205 2.08 ENSDART00000172989
bsnb
bassoon (presynaptic cytomatrix protein) b
chr19_+_1626598 2.07 ENSDART00000163539
scrt1a
scratch family zinc finger 1a
chr18_-_11426 2.05 ENSDART00000159781
WHAMM
WAS protein homolog associated with actin, golgi membranes and microtubules
chr17_+_9150326 2.05

chr9_-_5618609 2.05 ENSDART00000127219
FAM155A
family with sequence similarity 155 member A
chr6_+_12619062 2.04 ENSDART00000156341
fam117ba
family with sequence similarity 117, member Ba
chr19_+_41488385 2.03 ENSDART00000138687
ppp1r9a
protein phosphatase 1, regulatory subunit 9A
chr20_+_4078243 2.03 ENSDART00000124197
CU929133.1
ENSDARG00000088444
chr7_-_37587227 2.03 ENSDART00000173552
adcy7
adenylate cyclase 7
chr17_+_38619041 2.01 ENSDART00000145147
sptb
spectrin, beta, erythrocytic
KN150349v1_-_13313 2.01

chr9_-_695593 1.98 ENSDART00000115030
dip2a
disco-interacting protein 2 homolog A
chr3_-_45779817 1.96 ENSDART00000164361
gcgra
glucagon receptor a
chr2_-_53156364 1.96

chr25_-_22541525 1.95 ENSDART00000073583
islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr20_-_35343057 1.94 ENSDART00000113294
fzd3a
frizzled class receptor 3a
chr16_+_23172295 1.93 ENSDART00000167518
ENSDART00000161087
efna3b
ephrin-A3b
chr24_-_28166614 1.92 ENSDART00000167861
cox4i1l
cytochrome c oxidase subunit IV isoform 1, like
chr1_+_19942293 1.90 ENSDART00000148518
spock3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr5_-_20527105 1.89 ENSDART00000133461
camk2b1
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 1
chr21_+_142265 1.89

chr12_-_1931281 1.88 ENSDART00000005676
ENSDART00000127937
sox9a
SRY (sex determining region Y)-box 9a
chr3_-_1435654 1.88 ENSDART00000089646
ENSDART00000158110
fam234b
family with sequence similarity 234, member B
chr2_+_46179589 1.88 ENSDART00000125971
gpc1b
glypican 1b
chr2_+_49358871 1.87 ENSDART00000179089
sema6ba
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6Ba
chr13_+_35619748 1.84 ENSDART00000159690
gpr75
G protein-coupled receptor 75
chr19_-_22904687 1.83 ENSDART00000141503
pleca
plectin a
chr7_-_64637419 1.79 ENSDART00000020456
mmp15b
matrix metallopeptidase 15b
chr3_-_21217799 1.79 ENSDART00000114906
fam171a2a
family with sequence similarity 171, member A2a
chr25_+_34515221 1.78 ENSDART00000046218
flnca
filamin C, gamma a (actin binding protein 280)
chr1_-_35419335 1.76 ENSDART00000037516
znf827
zinc finger protein 827
chr11_+_41246824 1.76 ENSDART00000161605
iffo2b
intermediate filament family orphan 2b
chr23_-_1124499 1.76

chr20_+_1724609 1.75

chr24_+_4946079 1.73 ENSDART00000114537
zic4
zic family member 4
chr11_-_36503807 1.71 ENSDART00000002055
cacna2d3
calcium channel, voltage dependent, alpha2/delta subunit 3
chr11_-_33925792 1.71 ENSDART00000172978
atp13a3
ATPase type 13A3
chr12_-_954375 1.71 ENSDART00000054367
kdelr2b
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2b
chr24_+_10273081 1.70 ENSDART00000111014
myca
MYC proto-oncogene, bHLH transcription factor a
chr24_+_5811389 1.66 ENSDART00000139191
trpc1
transient receptor potential cation channel, subfamily C, member 1
chr9_+_8951400 1.66 ENSDART00000102562
ankrd10b
ankyrin repeat domain 10b
KN149883v1_-_5164 1.66 ENSDART00000158506
ENSDART00000172360
NDUFA13
NADH:ubiquinone oxidoreductase subunit A13
chr18_-_25190648 1.65 ENSDART00000175178
slco3a1
solute carrier organic anion transporter family, member 3A1
chr20_-_1293519 1.64 ENSDART00000152436
pcmt
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr8_-_4903896 1.64 ENSDART00000004986
igsf9b
immunoglobulin superfamily, member 9b
chr8_+_7237516 1.62

chr1_-_50215233 1.62 ENSDART00000137648
si:dkeyp-123h10.2
si:dkeyp-123h10.2
chr4_-_5755663 1.62 ENSDART00000113864
faxca
failed axon connections homolog a
chr5_+_68943914 1.61 ENSDART00000159594
mthfd2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr19_-_35512932 1.61

chr14_+_51653588 1.59 ENSDART00000157833
igfbp7
insulin-like growth factor binding protein 7
chr20_+_4222097 1.59 ENSDART00000097543
im:7142702
im:7142702
chr25_-_12107407 1.59 ENSDART00000159800
ENSDART00000091727
ntrk3a
neurotrophic tyrosine kinase, receptor, type 3a
chr20_-_8431338 1.57 ENSDART00000145841
ENSDART00000143936
ENSDART00000083906
ENSDART00000167102
ENSDART00000083908
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr25_-_20283460 1.54 ENSDART00000067454
kctd15a
potassium channel tetramerization domain containing 15a
chr20_+_26993709 1.54 ENSDART00000133293
ftr97
finTRIM family, member 97
chr18_+_44802349 1.54 ENSDART00000139526
fam118b
family with sequence similarity 118, member B
chr20_+_51034244 1.53

chr19_-_35513216 1.52

chr17_-_6191539 1.52 ENSDART00000081707
ENSDARG00000058775
ENSDARG00000058775
chr20_-_8431368 1.52 ENSDART00000145841
ENSDART00000143936
ENSDART00000083906
ENSDART00000167102
ENSDART00000083908
dab1a
Dab, reelin signal transducer, homolog 1a (Drosophila)
chr24_+_16249188 1.50 ENSDART00000164516
sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr12_+_26530620 1.50 ENSDART00000046959
arhgap12b
Rho GTPase activating protein 12b
chr6_+_4379989 1.49 ENSDART00000025031
pou4f1
POU class 4 homeobox 1
chr20_-_40217185 1.49

KN149842v1_+_13298 1.49 ENSDART00000166541
CABZ01101812.1
ENSDARG00000098297
chr20_-_20412830 1.49 ENSDART00000114779
ENSDARG00000079369
ENSDARG00000079369
chr10_+_45499009 1.49 ENSDART00000166085
ppiab
peptidylprolyl isomerase Ab (cyclophilin A)
chr14_-_49600662 1.47 ENSDART00000161147
si:ch211-154c21.1
si:ch211-154c21.1
chr7_+_39353662 1.46 ENSDART00000173847
ENSDART00000173845
ptpn5
protein tyrosine phosphatase, non-receptor type 5
chr23_-_19177660 1.46 ENSDART00000016901
pard6b
par-6 partitioning defective 6 homolog beta (C. elegans)
chr11_-_33697442 1.46 ENSDART00000087597
col6a2
collagen, type VI, alpha 2
chr12_+_1370058 1.45 ENSDART00000026303
rasd1
RAS, dexamethasone-induced 1
chr10_-_21096635 1.44 ENSDART00000091004
pcdh1a
protocadherin 1a
chr12_-_37124892 1.43 ENSDART00000146142
pmp22b
peripheral myelin protein 22b
chr7_-_49322226 1.43 ENSDART00000174161
brsk2b
BR serine/threonine kinase 2b
chr4_-_9172622 1.43 ENSDART00000042963
chst11
carbohydrate (chondroitin 4) sulfotransferase 11
chr20_-_54942216 1.42

chr25_+_34556009 1.41 ENSDART00000111706
si:dkey-108k21.14
si:dkey-108k21.14
chr1_-_7744605 1.41 ENSDART00000033917
syngr3b
synaptogyrin 3b
chr19_+_47846675 1.41 ENSDART00000041114
psmb2
proteasome subunit beta 2
chr11_-_10844854 1.40 ENSDART00000040180
tbr1a
T-box, brain, 1a
chr4_-_73485124 1.39 ENSDART00000122898
phf21b
PHD finger protein 21B
chr23_-_7740845 1.39 ENSDART00000172451
plagl2
pleiomorphic adenoma gene-like 2
chr13_+_29924636 1.38 ENSDART00000110061
spock2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr8_-_53584884 1.38

chr9_-_47041677 1.37 ENSDART00000054137
igfbp5b
insulin-like growth factor binding protein 5b
chr1_-_47080507 1.37 ENSDART00000101079
neurl1aa
neuralized E3 ubiquitin protein ligase 1Aa
chr13_-_36008571 1.37 ENSDART00000139593
pcnx
pecanex homolog (Drosophila)
chr6_+_56163589 1.36 ENSDART00000150219
tfap2c
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr22_-_6977038 1.36 ENSDART00000133143
ENSDART00000146813
gpd1b
glycerol-3-phosphate dehydrogenase 1b
chr14_+_14759351 1.35 ENSDART00000167075
nkx1.2lb
NK1 transcription factor related 2-like,b
chr20_+_48950833 1.34 ENSDART00000159275
nkx2.2b
NK2 homeobox 2b
chr4_-_25080470 1.33 ENSDART00000179640
gata3
GATA binding protein 3
chr12_-_45714172 1.33 ENSDART00000149044
pax2b
paired box 2b
KN150487v1_+_38777 1.33

chr12_-_1545172 1.33

chr23_+_36648211 1.33

chr12_-_28248133 1.33 ENSDART00000016283
psmd11b
proteasome 26S subunit, non-ATPase 11b
chr14_-_6624878 1.32 ENSDART00000166439
si:ch211-266k2.1
si:ch211-266k2.1
chr22_-_4622401 1.32 ENSDART00000106166
rx1
retinal homeobox gene 1
chr7_+_73371895 1.32 ENSDART00000110544
znf219
zinc finger protein 219
chr19_+_19839981 1.31 ENSDART00000113580
ENSDARG00000074216
ENSDARG00000074216
chr4_-_22751641 1.31 ENSDART00000066903
ENSDART00000130072
ENSDART00000123369
kmt2e
lysine (K)-specific methyltransferase 2E
chr25_-_211879 1.31 ENSDART00000021614
srpk2
SRSF protein kinase 2
chr7_+_32451041 1.30 ENSDART00000126565
si:ch211-150g13.3
si:ch211-150g13.3
chr3_-_42649955 1.29 ENSDART00000171213
uncx
UNC homeobox
chr16_-_204751 1.29

chr13_+_51769487 1.28 ENSDART00000169928
ENSDART00000160698
klhdc3
kelch domain containing 3
chr1_-_37990935 1.28 ENSDART00000132402
gpm6ab
glycoprotein M6Ab
chr21_-_661222 1.28

chr7_-_11812634 1.28 ENSDART00000101537
mex3b
mex-3 RNA binding family member B
chr15_+_46813538 1.28

chr10_-_27262050 1.27

chr11_-_45008060 1.26 ENSDART00000166691
trappc10
trafficking protein particle complex 10
chr4_-_12008472 1.26 ENSDART00000092250
btbd11a
BTB (POZ) domain containing 11a
chr23_-_104449 1.24

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.8 4.2 GO:0060844 smooth muscle tissue development(GO:0048745) arterial endothelial cell fate commitment(GO:0060844)
0.8 2.3 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.8 3.1 GO:0097476 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
0.7 5.1 GO:0072132 mesenchyme morphogenesis(GO:0072132)
0.7 3.5 GO:0090527 actin filament reorganization(GO:0090527)
0.7 4.7 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.6 1.8 GO:0048939 anterior lateral line nerve glial cell differentiation(GO:0048913) myelination of anterior lateral line nerve axons(GO:0048914) anterior lateral line nerve glial cell development(GO:0048939) anterior lateral line nerve glial cell morphogenesis involved in differentiation(GO:0048940)
0.6 3.0 GO:0048903 anterior lateral line neuromast development(GO:0048901) anterior lateral line neuromast hair cell differentiation(GO:0048903)
0.6 1.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.5 8.7 GO:0046653 tetrahydrofolate metabolic process(GO:0046653)
0.5 2.7 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.5 4.9 GO:0021754 facial nucleus development(GO:0021754)
0.5 6.7 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.5 1.4 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.4 1.2 GO:1903259 exon-exon junction complex disassembly(GO:1903259)
0.4 1.2 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.4 1.2 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.4 1.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.4 2.8 GO:2000637 negative regulation of hippo signaling(GO:0035331) positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.4 3.1 GO:1904825 protein localization to microtubule(GO:0035372) protein localization to microtubule plus-end(GO:1904825)
0.4 4.7 GO:0016203 muscle attachment(GO:0016203)
0.4 2.5 GO:2000480 regulation of cAMP-dependent protein kinase activity(GO:2000479) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.3 2.1 GO:1990709 presynaptic active zone organization(GO:1990709)
0.3 1.4 GO:1902176 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175) negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902176)
0.3 2.8 GO:0071678 olfactory bulb axon guidance(GO:0071678)
0.3 1.7 GO:0021534 cell proliferation in hindbrain(GO:0021534)
0.3 0.7 GO:0048659 smooth muscle cell proliferation(GO:0048659)
0.3 1.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 1.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.3 0.9 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.3 0.9 GO:0030431 sleep(GO:0030431)
0.3 0.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.3 0.8 GO:1902571 regulation of serine-type peptidase activity(GO:1902571)
0.3 1.4 GO:0046168 NADH oxidation(GO:0006116) glycerol-3-phosphate catabolic process(GO:0046168)
0.3 1.1 GO:0061550 cranial ganglion development(GO:0061550)
0.3 1.9 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.3 1.3 GO:0045582 positive regulation of T cell differentiation(GO:0045582)
0.3 1.1 GO:0043217 myelin maintenance(GO:0043217)
0.3 3.6 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.3 1.5 GO:0006621 protein retention in ER lumen(GO:0006621)
0.3 1.5 GO:0030575 nuclear body organization(GO:0030575) Cajal body organization(GO:0030576)
0.3 4.3 GO:0032836 glomerular basement membrane development(GO:0032836)
0.2 0.9 GO:0010801 regulation of peptidyl-threonine phosphorylation(GO:0010799) negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.2 2.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 2.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 3.6 GO:0061154 endothelial tube morphogenesis(GO:0061154) blood vessel lumenization(GO:0072554)
0.2 2.8 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.2 1.9 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 1.1 GO:0090317 negative regulation of intracellular protein transport(GO:0090317)
0.2 2.0 GO:0006171 cAMP biosynthetic process(GO:0006171)
0.2 0.6 GO:0070292 N-acylphosphatidylethanolamine metabolic process(GO:0070292)
0.2 1.9 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 0.5 GO:0072526 pyridine nucleotide catabolic process(GO:0019364) NAD catabolic process(GO:0019677) pyridine-containing compound catabolic process(GO:0072526)
0.2 1.6 GO:1990090 response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090)
0.2 2.9 GO:0071436 cellular potassium ion homeostasis(GO:0030007) sodium ion export from cell(GO:0036376) sodium ion export(GO:0071436)
0.2 0.8 GO:0035988 chondrocyte proliferation(GO:0035988)
0.2 2.7 GO:0014034 neural crest cell fate commitment(GO:0014034) neural crest cell fate specification(GO:0014036)
0.2 0.9 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 0.8 GO:0090104 pancreatic epsilon cell differentiation(GO:0090104)
0.1 3.4 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.1 0.7 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 1.7 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.1 2.5 GO:0001649 osteoblast differentiation(GO:0001649)
0.1 4.6 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1 1.7 GO:0046847 filopodium assembly(GO:0046847)
0.1 2.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 2.3 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.1 1.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 0.4 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.1 2.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.6 GO:0048899 anterior lateral line development(GO:0048899)
0.1 5.0 GO:0007050 cell cycle arrest(GO:0007050)
0.1 0.6 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.1 1.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.7 GO:0043535 regulation of blood vessel endothelial cell migration(GO:0043535)
0.1 3.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 2.4 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 1.3 GO:0043248 proteasome assembly(GO:0043248)
0.1 2.2 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.1 2.9 GO:0014866 skeletal myofibril assembly(GO:0014866)
0.1 3.3 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 3.1 GO:0030318 melanocyte differentiation(GO:0030318)
0.1 0.5 GO:0071379 cellular response to prostaglandin stimulus(GO:0071379)
0.1 1.3 GO:0021508 floor plate formation(GO:0021508) floor plate morphogenesis(GO:0033505)
0.1 3.8 GO:0060037 pharyngeal system development(GO:0060037)
0.1 0.9 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) negative regulation of microtubule polymerization or depolymerization(GO:0031111)
0.1 1.1 GO:0045332 phospholipid translocation(GO:0045332)
0.1 4.4 GO:0015718 monocarboxylic acid transport(GO:0015718)
0.1 0.4 GO:0051031 tRNA transport(GO:0051031)
0.1 1.6 GO:0001569 patterning of blood vessels(GO:0001569)
0.1 3.8 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.1 2.1 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.3 GO:0045428 regulation of nitric oxide biosynthetic process(GO:0045428) positive regulation of nitric oxide biosynthetic process(GO:0045429) positive regulation of reactive oxygen species biosynthetic process(GO:1903428) positive regulation of nitric oxide metabolic process(GO:1904407)
0.1 0.4 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 3.0 GO:0019722 calcium-mediated signaling(GO:0019722)
0.1 0.4 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.1 0.4 GO:0021548 pons development(GO:0021548)
0.1 1.3 GO:0035249 synaptic transmission, glutamatergic(GO:0035249)
0.1 0.7 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 3.4 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.1 0.2 GO:0048011 neurotrophin signaling pathway(GO:0038179) neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 1.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.8 GO:0060729 maintenance of gastrointestinal epithelium(GO:0030277) intestinal epithelial structure maintenance(GO:0060729)
0.1 1.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.1 2.1 GO:0010675 regulation of cellular carbohydrate metabolic process(GO:0010675) regulation of glucose metabolic process(GO:0010906)
0.1 0.9 GO:0006265 DNA topological change(GO:0006265)
0.1 0.8 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 1.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.0 0.4 GO:0060827 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823) regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.0 1.1 GO:0001885 endothelial cell development(GO:0001885)
0.0 0.3 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 0.6 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.5 GO:0048747 muscle fiber development(GO:0048747)
0.0 1.0 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 0.2 GO:0031641 regulation of myelination(GO:0031641)
0.0 1.7 GO:0006874 cellular calcium ion homeostasis(GO:0006874)
0.0 0.7 GO:0071391 cellular response to estrogen stimulus(GO:0071391)
0.0 0.5 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 3.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 1.1 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 1.5 GO:0007043 cell-cell junction assembly(GO:0007043)
0.0 0.6 GO:0007212 dopamine receptor signaling pathway(GO:0007212) optokinetic behavior(GO:0007634)
0.0 1.3 GO:0048821 erythrocyte development(GO:0048821)
0.0 1.7 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.8 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.6 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.4 GO:0021986 habenula development(GO:0021986)
0.0 0.6 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.3 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 0.6 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 2.3 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.0 2.3 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.0 0.5 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0048844 artery morphogenesis(GO:0048844)
0.0 0.4 GO:0048634 regulation of muscle organ development(GO:0048634)
0.0 1.3 GO:0030903 notochord development(GO:0030903)
0.0 0.7 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.8 GO:1901800 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436) positive regulation of proteasomal protein catabolic process(GO:1901800)
0.0 0.1 GO:0019405 alditol catabolic process(GO:0019405)
0.0 3.5 GO:0042060 wound healing(GO:0042060)
0.0 0.7 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.2 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.3 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 1.6 GO:0098609 cell-cell adhesion(GO:0098609)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0030314 junctional membrane complex(GO:0030314)
0.7 4.8 GO:0044295 axonal growth cone(GO:0044295)
0.5 2.7 GO:0098844 postsynaptic endocytic zone membrane(GO:0098844)
0.4 5.8 GO:0005869 dynactin complex(GO:0005869)
0.4 2.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.4 2.1 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831)
0.4 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.4 2.0 GO:0008091 spectrin(GO:0008091)
0.4 2.9 GO:1904949 sodium:potassium-exchanging ATPase complex(GO:0005890) cation-transporting ATPase complex(GO:0090533) ATPase dependent transmembrane transport complex(GO:0098533) ATPase complex(GO:1904949)
0.3 4.7 GO:0031594 neuromuscular junction(GO:0031594)
0.3 1.9 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.3 2.8 GO:0043256 basal lamina(GO:0005605) laminin complex(GO:0043256)
0.2 1.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 2.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 2.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.2 3.0 GO:0043195 terminal bouton(GO:0043195)
0.2 3.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.2 1.8 GO:0030056 hemidesmosome(GO:0030056)
0.2 1.8 GO:0009925 basal plasma membrane(GO:0009925)
0.2 3.1 GO:0035371 microtubule plus-end(GO:0035371)
0.2 1.1 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 1.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 1.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 3.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.4 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.1 2.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 2.4 GO:0030175 filopodium(GO:0030175)
0.1 0.9 GO:0036449 microtubule minus-end(GO:0036449)
0.1 7.5 GO:1990204 oxidoreductase complex(GO:1990204)
0.1 1.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.0 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.5 GO:0015030 Cajal body(GO:0015030)
0.1 1.7 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 4.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 0.7 GO:0046930 pore complex(GO:0046930)
0.1 1.3 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.4 GO:0005839 proteasome core complex(GO:0005839)
0.1 1.5 GO:0032156 septin ring(GO:0005940) septin complex(GO:0031105) septin cytoskeleton(GO:0032156)
0.1 3.1 GO:0014069 postsynaptic density(GO:0014069)
0.1 3.0 GO:0016459 myosin complex(GO:0016459)
0.1 2.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 0.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 2.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 3.5 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 7.2 GO:0005911 cell-cell junction(GO:0005911)
0.0 4.2 GO:0030425 dendrite(GO:0030425)
0.0 3.2 GO:0005882 intermediate filament(GO:0005882)
0.0 20.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.4 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.6 GO:0009986 cell surface(GO:0009986)
0.0 0.4 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.0 GO:0035770 ribonucleoprotein granule(GO:0035770) cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 11.4 GO:0005615 extracellular space(GO:0005615)
0.0 29.4 GO:0005886 plasma membrane(GO:0005886)
0.0 0.6 GO:0031201 SNARE complex(GO:0031201)
0.0 0.2 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.3 GO:0044545 NSL complex(GO:0044545)
0.0 0.3 GO:0005604 basement membrane(GO:0005604) extracellular matrix component(GO:0044420)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0005845 mRNA cap binding complex(GO:0005845)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.9 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.3 GO:0033290 eukaryotic 48S preinitiation complex(GO:0033290)
0.0 1.2 GO:0045202 synapse(GO:0045202)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
1.2 3.6 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
1.1 4.2 GO:0008142 oxysterol binding(GO:0008142)
0.9 3.5 GO:0030274 LIM domain binding(GO:0030274)
0.8 1.6 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.6 3.4 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.6 1.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.5 2.1 GO:0098882 structural constituent of presynaptic active zone(GO:0098882)
0.5 4.6 GO:0070700 BMP receptor binding(GO:0070700)
0.5 2.0 GO:0004016 adenylate cyclase activity(GO:0004016)
0.5 1.9 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.4 1.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.4 1.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.4 2.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.4 4.9 GO:0005324 long-chain fatty acid transporter activity(GO:0005324) fatty acid transporter activity(GO:0015245)
0.3 1.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.3 2.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.3 1.2 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.3 1.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.3 1.4 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.3 2.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.3 1.8 GO:0001637 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950) C-C chemokine receptor activity(GO:0016493)
0.3 4.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.3 3.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 2.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812)
0.2 2.3 GO:0031995 insulin-like growth factor I binding(GO:0031994) insulin-like growth factor II binding(GO:0031995)
0.2 0.7 GO:0015288 porin activity(GO:0015288)
0.2 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.2 0.9 GO:0030507 spectrin binding(GO:0030507)
0.2 2.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.2 1.2 GO:0015250 water channel activity(GO:0015250)
0.2 1.4 GO:0001727 lipid kinase activity(GO:0001727)
0.2 1.4 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 0.9 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 0.5 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.2 2.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 0.9 GO:0033149 FFAT motif binding(GO:0033149)
0.2 8.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 2.9 GO:0001671 ATPase activator activity(GO:0001671)
0.2 0.8 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.2 2.0 GO:0017046 peptide hormone binding(GO:0017046)
0.2 1.1 GO:0004970 ionotropic glutamate receptor activity(GO:0004970)
0.2 1.6 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.2 0.5 GO:0004953 icosanoid receptor activity(GO:0004953)
0.2 4.7 GO:0005178 integrin binding(GO:0005178)
0.2 1.7 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 4.7 GO:0019955 cytokine binding(GO:0019955)
0.2 3.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 4.4 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 2.2 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 2.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 1.9 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.5 GO:0005080 protein kinase C binding(GO:0005080)
0.1 2.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.8 GO:0017091 AU-rich element binding(GO:0017091) mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 1.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.1 0.6 GO:0031682 G-protein gamma-subunit binding(GO:0031682)
0.1 2.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 2.3 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.1 3.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.3 GO:0016403 dimethylargininase activity(GO:0016403)
0.1 0.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 1.2 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.1 5.5 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.5 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.1 2.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 0.2 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.1 5.8 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.1 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 1.5 GO:0043022 ribosome binding(GO:0043022)
0.1 1.7 GO:0005048 signal sequence binding(GO:0005048)
0.0 0.7 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.0 0.8 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.7 GO:0031267 small GTPase binding(GO:0031267)
0.0 0.6 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 2.3 GO:0005126 cytokine receptor binding(GO:0005126)
0.0 1.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 5.5 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 2.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.7 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 4.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.6 GO:0031386 protein tag(GO:0031386)
0.0 0.6 GO:0009931 protein kinase C activity(GO:0004697) calcium-dependent protein kinase C activity(GO:0004698) calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.0 0.9 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.4 GO:0002039 p53 binding(GO:0002039)
0.0 2.2 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 2.8 GO:0003774 motor activity(GO:0003774)
0.0 31.8 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 6.5 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.6 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 1.0 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.5 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.0 GO:0015293 symporter activity(GO:0015293)
0.0 0.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.4 GO:0000149 SNARE binding(GO:0000149)
0.0 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 2.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0000049 tRNA binding(GO:0000049)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 PID LPA4 PATHWAY LPA4-mediated signaling events
0.6 4.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 3.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.2 7.6 PID AURORA B PATHWAY Aurora B signaling
0.2 4.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 3.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.2 1.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.9 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 1.3 PID IL27 PATHWAY IL27-mediated signaling events
0.1 3.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 1.5 NABA COLLAGENS Genes encoding collagen proteins
0.1 5.4 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 1.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 2.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.1 5.6 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.3 2.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 3.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.2 2.3 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.2 1.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.2 1.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 1.8 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 4.2 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 5.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 1.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 4.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 2.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 2.3 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.0 1.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 2.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein