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Results for zbtb42

Z-value: 1.78

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Transcription factors associated with zbtb42

Gene Symbol Gene ID Gene Info
zbtb42
ENSDARG00000102761 zinc finger and BTB domain containing 42

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
zbtb42dr10_dc_chr17_-_756401_7564870.932.0e-07Click!

Activity profile of zbtb42 motif

Sorted Z-values of zbtb42 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of zbtb42

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr19_-_5781358 6.05 ENSDART00000082050
zgc:174904
zgc:174904
chr16_-_26803204 5.94 ENSDART00000162665
esrp1
epithelial splicing regulatory protein 1
chr9_-_33584190 5.66 ENSDART00000138844
caska
calcium/calmodulin-dependent serine protein kinase a
chr15_-_14616083 4.78 ENSDART00000171169
numbl
numb homolog (Drosophila)-like
chr7_+_34018862 4.72 ENSDART00000123498
fibinb
fin bud initiation factor b
chr13_+_11912981 4.48 ENSDART00000158244
gng2
guanine nucleotide binding protein (G protein), gamma 2
chr15_+_34131126 4.46 ENSDART00000169487
vwde
von Willebrand factor D and EGF domains
chr1_-_11286438 4.42 ENSDART00000159981
ENSDART00000066638
grk4
G protein-coupled receptor kinase 4
chr20_+_2443682 4.38 ENSDART00000131642
akap7
A kinase (PRKA) anchor protein 7
chr13_-_13163676 4.36 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
chr5_-_13872815 4.08 ENSDART00000164698
CT009570.1
ENSDARG00000104490
chr16_+_42925950 4.05 ENSDART00000159730
ENSDART00000014956
polr3glb
polymerase (RNA) III (DNA directed) polypeptide G like b
chr12_-_34614931 4.02 ENSDART00000152876
bahcc1b
BAH domain and coiled-coil containing 1b
chr9_+_7609372 3.99

chr10_-_11806373 3.96 ENSDART00000009715
adamts6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr24_-_1307905 3.89 ENSDART00000159212
nrp1a
neuropilin 1a
chr4_-_2615160 3.84 ENSDART00000140760
e2f7
E2F transcription factor 7
chr15_-_4322875 3.71 ENSDART00000173311
si:ch211-117a13.2
si:ch211-117a13.2
chr9_-_9864049 3.69 ENSDART00000121456
fstl1b
follistatin-like 1b
chr7_-_25623974 3.69 ENSDART00000173602
cd99l2
CD99 molecule-like 2
chr7_+_23306546 3.58 ENSDART00000049885
si:dkey-172j4.3
si:dkey-172j4.3
chr22_-_11712371 3.49

chr23_+_21546553 3.41 ENSDART00000142921
si:ch73-21g5.7
si:ch73-21g5.7
chr4_-_76594677 3.40 ENSDART00000049170
zgc:85975
zgc:85975
chr10_-_22834248 3.39 ENSDART00000079469
pcolcea
procollagen C-endopeptidase enhancer a
chr21_-_20305406 3.29 ENSDART00000065659
rbp4l
retinol binding protein 4, like
chr17_+_29328653 3.24 ENSDART00000086164
kctd3
potassium channel tetramerization domain containing 3
chr2_+_11902170 3.15 ENSDART00000138562
greb1l
growth regulation by estrogen in breast cancer-like
chr17_-_14551031 3.02 ENSDART00000162452
daam1a
dishevelled associated activator of morphogenesis 1a
chr9_+_7609527 3.01

chr1_+_31131899 2.97 ENSDART00000075260
inab
internexin neuronal intermediate filament protein, alpha b
chr19_+_47719438 2.94 ENSDART00000138295
ext1c
exostoses (multiple) 1c
chr3_-_39245184 2.91

chr22_+_17091411 2.82 ENSDART00000170076
frem1b
Fras1 related extracellular matrix 1b
chr2_+_31399487 2.71 ENSDART00000086863
colec12
collectin sub-family member 12
chr23_+_36010592 2.69 ENSDART00000137507
hoxc3a
homeo box C3a
chr13_-_13163801 2.69 ENSDART00000156968
fgfr3
fibroblast growth factor receptor 3
chr19_-_22894525 2.61 ENSDART00000090679
pleca
plectin a
KN150108v1_+_18276 2.59

chr11_-_42826276 2.54

chr13_-_25067585 2.52 ENSDART00000159585
adka
adenosine kinase a
chr10_+_7043530 2.52

chr4_+_4223606 2.43

chr19_+_5399813 2.42 ENSDART00000145749
si:dkeyp-113d7.1
si:dkeyp-113d7.1
chr16_-_13704905 2.36 ENSDART00000060004
ntd5
ntl-dependent gene 5
chr18_-_46243753 2.31 ENSDART00000145999
prx
periaxin
chr7_+_5372830 2.28 ENSDART00000135271
MYADM
myeloid associated differentiation marker
chr25_-_4376129 2.25

chr11_-_42826308 2.25

chr12_+_22734974 2.19 ENSDART00000130594
afap1
actin filament associated protein 1
chr21_-_18969970 2.14 ENSDART00000080269
pgam2
phosphoglycerate mutase 2 (muscle)
chr14_-_35332747 2.11 ENSDART00000074710
pdgfc
platelet derived growth factor c
chr24_+_28364360 2.10 ENSDART00000018037
arhgap29a
Rho GTPase activating protein 29a
chr7_+_28862183 2.06 ENSDART00000052346
gnao1b
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b
chr17_+_11353143 2.06 ENSDART00000013170
kif26ba
kinesin family member 26Ba
chr5_-_19357961 2.05 ENSDART00000088904
ENSDART00000163701
gltpa
glycolipid transfer protein a
chr5_-_33169062 2.04 ENSDART00000133504
dab2ipb
DAB2 interacting protein b
chr12_+_13614102 2.02 ENSDART00000152689
oplah
5-oxoprolinase (ATP-hydrolysing)
chr1_+_58029993 2.00

chr3_+_17387551 1.97 ENSDART00000104549
hcrt
hypocretin (orexin) neuropeptide precursor
chr20_+_14979154 1.96 ENSDART00000118157
dre-mir-199-1
dre-mir-199-1
chr3_-_32464649 1.96 ENSDART00000103239
tspan4b
tetraspanin 4b
chr17_-_756401 1.94 ENSDART00000157622
zbtb42
zinc finger and BTB domain containing 42
chr25_+_34997593 1.93 ENSDART00000058443
fibina
fin bud initiation factor a
chr4_-_76594399 1.91 ENSDART00000049170
zgc:85975
zgc:85975
chr3_-_54414513 1.91 ENSDART00000053106
s1pr2
sphingosine-1-phosphate receptor 2
chr16_-_20901879 1.84 ENSDART00000103630
creb5b
cAMP responsive element binding protein 5b
chr20_+_23339698 1.81 ENSDART00000074167
ociad2
OCIA domain containing 2
chr12_+_27612667 1.77 ENSDART00000153256
cacna1g
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr20_-_40553998 1.76 ENSDART00000075092
pkib
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr12_+_20578266 1.75 ENSDART00000016099
ENSDARG00000043818
ENSDARG00000043818
chr2_+_5881998 1.75 ENSDART00000158045
ENSDART00000028703
slc35d1b
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1b
chr17_-_35004687 1.71

chr1_+_44660098 1.67 ENSDART00000145486
si:ch211-243a20.3
si:ch211-243a20.3
chr9_+_3416651 1.63 ENSDART00000019910
dlx1a
distal-less homeobox 1a
chr17_+_45961986 1.60

chr10_+_20112765 1.57 ENSDART00000027612
xpo7
exportin 7
chr20_-_47576935 1.55 ENSDART00000067776
rab10
RAB10, member RAS oncogene family
chr13_+_18414806 1.54 ENSDART00000110197
zgc:154058
zgc:154058
chr4_+_22754618 1.54

chr9_-_31079647 1.53

chr10_-_30016761 1.48 ENSDART00000078800
lim2.1
lens intrinsic membrane protein 2.1
chr3_+_19582280 1.46 ENSDART00000109409
mrc2
mannose receptor, C type 2
chr2_-_37061470 1.46 ENSDART00000056514
gng7
guanine nucleotide binding protein (G protein), gamma 7
chr19_+_5399877 1.46 ENSDART00000145749
si:dkeyp-113d7.1
si:dkeyp-113d7.1
chr19_-_44495755 1.44 ENSDART00000132800
rad21b
RAD21 cohesin complex component b
chr10_-_24401876 1.42 ENSDART00000149362
pitpnab
phosphatidylinositol transfer protein, alpha b
chr20_+_6600246 1.42 ENSDART00000136567
tns3.2
tensin 3, tandem duplicate 2
chr16_+_9718837 1.41 ENSDART00000047920
enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr10_+_9134634 1.38 ENSDART00000110443
fstb
follistatin b
chr18_+_512813 1.37 ENSDART00000162513
gpib
glucose-6-phosphate isomerase b
chr23_-_27930478 1.37 ENSDART00000043462
acvrl1
activin A receptor type II-like 1
chr17_+_38307512 1.36 ENSDART00000005296
nkx2.9
NK2 transcription factor related, locus 9 (Drosophila)
chr9_+_22953351 1.35 ENSDART00000090875
tnfaip6
tumor necrosis factor, alpha-induced protein 6
chr20_+_6600184 1.35 ENSDART00000136567
tns3.2
tensin 3, tandem duplicate 2
chr23_+_41295092 1.34 ENSDART00000109567
nhsa
Nance-Horan syndrome a (congenital cataracts and dental anomalies)
chr20_+_51034244 1.34

chr14_-_45887648 1.34 ENSDART00000074208
cltb
clathrin, light chain B
chr12_-_28766713 1.33 ENSDART00000148459
cbx1b
chromobox homolog 1b (HP1 beta homolog Drosophila)
chr19_-_20508993 1.28 ENSDART00000129917
mpp6b
membrane protein, palmitoylated 6b (MAGUK p55 subfamily member 6)
chr8_+_39762186 1.28 ENSDART00000143413
si:ch211-170d8.2
si:ch211-170d8.2
chr18_+_48959401 1.27 ENSDART00000158104
SHKBP1
SH3KBP1 binding protein 1
chr1_+_58030069 1.27

chr19_+_19916407 1.25 ENSDART00000166755
tril
TLR4 interactor with leucine-rich repeats
chr17_-_20267580 1.24 ENSDART00000078703
add3b
adducin 3 (gamma) b
chr3_-_36697213 1.24 ENSDART00000154553
ramp2
receptor (G protein-coupled) activity modifying protein 2
chr20_+_29685096 1.23 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr6_+_39838929 1.19 ENSDART00000112637
smarcc2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr23_+_41129663 1.17

chr24_+_34227202 1.16 ENSDART00000105572
gbx1
gastrulation brain homeobox 1
chr2_-_24947660 1.13 ENSDART00000113356
ENSDART00000163038
crtc1a
CREB regulated transcription coactivator 1a
chr23_+_20050920 1.13 ENSDART00000144790
cfap126
cilia and flagella associated protein 126
chr24_-_28166614 1.11 ENSDART00000167861
cox4i1l
cytochrome c oxidase subunit IV isoform 1, like
chr14_-_23501428 1.06

chr22_-_29133832 1.04 ENSDART00000172576
cbx6a
chromobox homolog 6a
chr19_+_47719402 1.03 ENSDART00000138295
ext1c
exostoses (multiple) 1c
chr24_+_30343687 1.02 ENSDART00000162377
FP085414.1
ENSDARG00000100270
chr6_-_43273456 1.01

chr10_-_20524670 1.00

chr24_-_25021505 0.99 ENSDART00000141601
phldb2b
pleckstrin homology-like domain, family B, member 2b
chr2_-_44893769 0.99 ENSDART00000041806
acsm3
acyl-CoA synthetase medium-chain family member 3
chr18_+_48959017 0.98 ENSDART00000158104
SHKBP1
SH3KBP1 binding protein 1
chr19_-_36009321 0.98 ENSDART00000136811
col8a2
collagen, type VIII, alpha 2
chr16_-_26803131 0.96 ENSDART00000103431
esrp1
epithelial splicing regulatory protein 1
chr9_+_32547244 0.95 ENSDART00000144608
plcl1
phospholipase C-like 1
chr5_-_13872772 0.94 ENSDART00000164698
CT009570.1
ENSDARG00000104490
chr24_-_1308047 0.93 ENSDART00000164904
nrp1a
neuropilin 1a
chr10_-_20524586 0.90

chr13_-_13163647 0.89 ENSDART00000125883
ENSDART00000013534
fgfr3
fibroblast growth factor receptor 3
chr14_+_15698814 0.84

chr4_+_12613575 0.72 ENSDART00000133767
lmo3
LIM domain only 3
chr5_-_21578927 0.68 ENSDART00000020908
zc4h2
zinc finger, C4H2 domain containing
chr16_-_51087813 0.68 ENSDART00000165408
si:dkeyp-97a10.3
si:dkeyp-97a10.3
chr24_-_37989964 0.65 ENSDART00000128574
tmem204
transmembrane protein 204
chr5_-_18510716 0.64 ENSDART00000002624
ENSDART00000110553
ranbp1
RAN binding protein 1
chr5_-_38873781 0.64 ENSDART00000171557
antxr2a
anthrax toxin receptor 2a
chr11_-_27970634 0.63

chr7_-_38340949 0.63 ENSDART00000173678
c1qtnf4
C1q and TNF related 4
chr25_-_31049247 0.58 ENSDART00000009126
kras
v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
chr22_+_17581859 0.54 ENSDART00000035670
polr2eb
polymerase (RNA) II (DNA directed) polypeptide E, b
chr23_-_27930393 0.51 ENSDART00000043462
acvrl1
activin A receptor type II-like 1
chr18_+_45553846 0.50 ENSDART00000138075
kifc3
kinesin family member C3
chr5_-_41044841 0.50 ENSDART00000051092
riok2
RIO kinase 2 (yeast)
chr1_-_17894339 0.48 ENSDART00000131548
fam114a1
family with sequence similarity 114, member A1
chr20_+_14978952 0.46 ENSDART00000118157
dre-mir-199-1
dre-mir-199-1
chr6_+_28232386 0.45 ENSDART00000163057
FP101882.1
ENSDARG00000098121
chr22_+_25570287 0.44

chr4_-_9608687 0.43 ENSDART00000067188
dclre1c
DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)
chr13_+_11304073 0.43 ENSDART00000169895
zbtb18
zinc finger and BTB domain containing 18
chr2_-_52041699 0.41 ENSDART00000165568
pigr
polymeric immunoglobulin receptor
chr5_-_51352096 0.41 ENSDART00000097194
serinc5
serine incorporator 5
chr25_-_11287103 0.40 ENSDART00000166586
enc2
ectodermal-neural cortex 2
chr10_-_2944221 0.38 ENSDART00000132526
marveld2a
MARVEL domain containing 2a
chr10_+_28700844 0.38 ENSDART00000047776
cblb
Cbl proto-oncogene B, E3 ubiquitin protein ligase
chr6_-_45993454 0.38 ENSDART00000154392
ca16b
carbonic anhydrase XVI b
chr13_+_30968221 0.36 ENSDART00000014922
arhgap22
Rho GTPase activating protein 22
chr2_-_37061049 0.35 ENSDART00000131834
gng7
guanine nucleotide binding protein (G protein), gamma 7
chr23_-_439495 0.30 ENSDART00000146776
tspan2b
tetraspanin 2b
chr12_-_36145252 0.29

chr5_-_12789388 0.28

chr7_-_51877974 0.26 ENSDART00000122104
CT737190.1
ENSDARG00000091514
chr12_-_34615030 0.25 ENSDART00000152876
bahcc1b
BAH domain and coiled-coil containing 1b
chr25_+_2623389 0.24 ENSDART00000156567
neo1b
neogenin 1b
chr13_+_24266204 0.23 ENSDART00000101200
ENSDART00000166005
zgc:153169
zgc:153169
chr19_+_19916372 0.23 ENSDART00000166755
tril
TLR4 interactor with leucine-rich repeats
chr4_+_274394 0.22

chr9_+_7609341 0.20

chr6_-_7094523 0.20

chr17_-_30822468 0.20 ENSDART00000139707
gdf7
growth differentiation factor 7
chr20_+_29685331 0.19 ENSDART00000153339
adam17b
ADAM metallopeptidase domain 17b
chr5_-_51351827 0.19 ENSDART00000097194
serinc5
serine incorporator 5
chr12_-_34614903 0.17 ENSDART00000152876
bahcc1b
BAH domain and coiled-coil containing 1b
chr9_+_7477732 0.16 ENSDART00000061723
tmem198a
transmembrane protein 198a
chr12_-_26291790 0.15 ENSDART00000152941
usp54b
ubiquitin specific peptidase 54b
chr17_-_8570443 0.13 ENSDART00000049236
ctbp2a
C-terminal binding protein 2a
chr10_-_20524860 0.10

chr14_-_50122491 0.08 ENSDART00000133811
sfxn1
sideroflexin 1
chr1_-_9201151 0.08 ENSDART00000138630
zgc:56409
zgc:56409
chr5_-_21384509 0.07 ENSDART00000020725
smarca1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr4_-_16356247 0.05 ENSDART00000079521
kera
keratocan
chr11_+_34659252 0.04 ENSDART00000128070
gnai2a
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a
chr22_-_20141216 0.03 ENSDART00000128023
btbd2a
BTB (POZ) domain containing 2a
chr25_-_31496617 0.00 ENSDART00000155106
ENSDARG00000097988
ENSDARG00000097988

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0060055 larval development(GO:0002164) larval heart development(GO:0007508) angiogenesis involved in wound healing(GO:0060055)
1.5 4.4 GO:0051701 interaction with host(GO:0051701)
1.3 3.8 GO:0032877 regulation of DNA endoreduplication(GO:0032875) positive regulation of DNA endoreduplication(GO:0032877) DNA endoreduplication(GO:0042023)
0.8 2.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.7 2.0 GO:0030431 temperature homeostasis(GO:0001659) sleep(GO:0030431)
0.6 2.5 GO:0044209 AMP salvage(GO:0044209)
0.6 1.8 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.5 1.6 GO:1902869 negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of amacrine cell differentiation(GO:1902869) positive regulation of amacrine cell differentiation(GO:1902871)
0.4 3.6 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.4 1.4 GO:0050848 regulation of calcium-mediated signaling(GO:0050848)
0.3 2.0 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.3 1.9 GO:0034405 response to fluid shear stress(GO:0034405)
0.3 2.1 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.3 1.8 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479) negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.2 1.0 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228)
0.2 7.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.2 4.8 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.2 1.4 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.2 1.1 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.2 1.4 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.2 4.5 GO:0048010 vascular endothelial growth factor receptor signaling pathway(GO:0048010)
0.2 1.6 GO:0006611 protein export from nucleus(GO:0006611)
0.2 4.7 GO:0035118 embryonic pectoral fin morphogenesis(GO:0035118)
0.2 2.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.6 GO:1901998 toxin transport(GO:1901998)
0.1 1.2 GO:0060827 regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060827)
0.1 0.4 GO:0035676 anterior lateral line neuromast hair cell development(GO:0035676)
0.1 4.0 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.3 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 4.0 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1 1.1 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.4 GO:0043247 protection from non-homologous end joining at telomere(GO:0031848) telomere maintenance in response to DNA damage(GO:0043247)
0.1 0.6 GO:0007100 mitotic centrosome separation(GO:0007100) positive regulation of centrosome cycle(GO:0046607) centrosome separation(GO:0051299)
0.1 2.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 1.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.1 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 1.9 GO:0021986 habenula development(GO:0021986)
0.1 1.4 GO:0051156 glucose 6-phosphate metabolic process(GO:0051156)
0.1 2.1 GO:0007520 myoblast fusion(GO:0007520)
0.1 5.7 GO:0021782 glial cell development(GO:0021782)
0.1 2.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.4 GO:0021514 ventral spinal cord interneuron differentiation(GO:0021514)
0.1 2.7 GO:0001570 vasculogenesis(GO:0001570)
0.1 1.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 3.2 GO:0051260 protein homooligomerization(GO:0051260)
0.1 0.6 GO:0006658 phosphatidylserine metabolic process(GO:0006658)
0.0 1.2 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 5.9 GO:0043484 regulation of RNA splicing(GO:0043484)
0.0 0.7 GO:0070593 dendrite self-avoidance(GO:0070593)
0.0 4.9 GO:0030198 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.0 0.7 GO:0048665 neuron fate specification(GO:0048665)
0.0 2.5 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.5 GO:0060034 notochord cell differentiation(GO:0060034)
0.0 1.2 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 1.3 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 0.1 GO:0070073 clustering of voltage-gated calcium channels(GO:0070073)
0.0 1.0 GO:0010506 regulation of autophagy(GO:0010506)
0.0 1.0 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 1.5 GO:0048793 pronephros development(GO:0048793)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.0 GO:0005883 neurofilament(GO:0005883)
0.6 6.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.5 1.4 GO:0030892 nuclear cohesin complex(GO:0000798) mitotic cohesin complex(GO:0030892) nuclear mitotic cohesin complex(GO:0034990) nuclear meiotic cohesin complex(GO:0034991)
0.5 1.9 GO:0070724 BMP receptor complex(GO:0070724)
0.4 1.3 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.3 1.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.2 2.6 GO:0030056 hemidesmosome(GO:0030056)
0.2 4.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 1.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.2 GO:0071564 npBAF complex(GO:0071564)
0.1 0.4 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 0.6 GO:0070938 contractile ring(GO:0070938)
0.1 2.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.7 GO:0005581 collagen trimer(GO:0005581)
0.0 2.2 GO:0005643 nuclear pore(GO:0005643)
0.0 1.9 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.1 GO:0005871 kinesin complex(GO:0005871)
0.0 7.9 GO:0043235 receptor complex(GO:0043235)
0.0 3.8 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 29.3 GO:0005576 extracellular region(GO:0005576)
0.0 4.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.2 GO:0014069 postsynaptic density(GO:0014069)
0.0 1.1 GO:0016324 apical plasma membrane(GO:0016324) apical part of cell(GO:0045177)
0.0 0.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.8 2.5 GO:0004001 adenosine kinase activity(GO:0004001)
0.7 4.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.7 3.3 GO:0034632 retinol transporter activity(GO:0034632)
0.6 1.8 GO:0005463 UDP-glucuronic acid transmembrane transporter activity(GO:0005461) UDP-N-acetylgalactosamine transmembrane transporter activity(GO:0005463)
0.5 2.2 GO:0042169 SH2 domain binding(GO:0042169)
0.5 2.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.5 4.8 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.5 6.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.5 7.9 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.4 3.8 GO:0001217 bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding(GO:0001130) bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding(GO:0001217)
0.4 3.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.4 2.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619)
0.3 1.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 2.1 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.3 1.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.3 1.8 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2 2.6 GO:0030506 ankyrin binding(GO:0030506)
0.2 1.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.2 2.1 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 1.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 2.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 1.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 1.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 1.9 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 1.4 GO:0048185 activin binding(GO:0048185)
0.1 2.0 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 1.0 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.4 GO:0047690 aspartyltransferase activity(GO:0047690)
0.1 1.2 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.1 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.8 GO:0035497 cAMP response element binding(GO:0035497)
0.1 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 1.0 GO:0016408 C-acyltransferase activity(GO:0016408)
0.1 1.1 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 1.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.4 GO:0008201 heparin binding(GO:0008201)
0.0 0.6 GO:0031267 small GTPase binding(GO:0031267)
0.0 3.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 2.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.7 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 1.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 4.8 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.0 0.1 GO:0022889 serine transmembrane transporter activity(GO:0022889)
0.0 1.2 GO:0042393 histone binding(GO:0042393)
0.0 4.0 GO:0003682 chromatin binding(GO:0003682)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 7.9 PID FGF PATHWAY FGF signaling pathway
0.1 1.9 PID ALK1 PATHWAY ALK1 signaling events
0.1 5.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.3 PID ARF 3PATHWAY Arf1 pathway
0.1 4.5 PID E2F PATHWAY E2F transcription factor network
0.1 0.4 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 2.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 4.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.4 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 2.3 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 7.9 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.6 6.3 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.4 2.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.2 1.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 2.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 2.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME CLASS A1 RHODOPSIN LIKE RECEPTORS Genes involved in Class A/1 (Rhodopsin-like receptors)
0.0 1.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis