ISMARA results: zic3

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Results for zic3

Z-value: 0.43

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Transcription factors associated with zic3

Gene Symbol	Gene ID	Gene Info
zic3 NCBI UniProt ZFIN ENSEMBL Google	ENSDARG00000071497	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
zic3	dr10_dc_chr14_-_31676235_31676332	-0.88	5.6e-06	Click!

Activity profile of zic3 motif

Sorted Z-values of zic3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of zic3

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Promoter	Score	Transcript	Gene	Gene Info
chr22_-_20236308 Show fit	0.96
chr22_+_37688839 Show fit	0.91	ENSDART00000174664 ENSDART00000178200	FO704589.1 NCBI UniProt ZFIN ENSEMBL Google Show fit	ENSDARG00000108910
chr19_+_24398149 Show fit	0.79	ENSDART00000080673	syt11a NCBI UniProt ZFIN ENSEMBL Google Show fit	synaptotagmin XIa
chr9_-_3548211 Show fit	0.74	ENSDART00000145043 ENSDART00000169586	dcaf17 NCBI UniProt ZFIN ENSEMBL Google Show fit	ddb1 and cul4 associated factor 17
chr6_+_27100350 Show fit	0.69	ENSDART00000121558	atg4b NCBI UniProt ZFIN ENSEMBL Google Show fit	autophagy related 4B, cysteine peptidase
chr22_+_37689055 Show fit	0.60
chr6_+_27100249 Show fit	0.51	ENSDART00000121558	atg4b NCBI UniProt ZFIN ENSEMBL Google Show fit	autophagy related 4B, cysteine peptidase
chr9_-_9729041 Show fit	0.51	ENSDART00000175212	gpr156 NCBI UniProt ZFIN ENSEMBL Google Show fit	G protein-coupled receptor 156
chr2_-_30800968 Show fit	0.45	ENSDART00000056735	rgs20 NCBI UniProt ZFIN ENSEMBL Google Show fit	regulator of G protein signaling 20
chr25_-_34235582 Show fit	0.39	ENSDART00000137665	frs2b NCBI UniProt ZFIN ENSEMBL Google Show fit	fibroblast growth factor receptor substrate 2b

Showing 1 to 10 of 18 entries

Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.6	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0	0.5	GO:0014046	dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1	0.4	GO:0046078	dUMP biosynthetic process(GO:0006226) dUMP metabolic process(GO:0046078)
0.0	0.4	GO:0007257	activation of JUN kinase activity(GO:0007257) positive regulation of JUN kinase activity(GO:0043507)
0.0	0.2	GO:0051489	regulation of filopodium assembly(GO:0051489)

Showing 1 to 5 of 5 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.7	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1	0.5	GO:0038039	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor heterodimeric complex(GO:0038039) G-protein coupled receptor complex(GO:0097648)
0.1	0.2	GO:0044326	dendritic spine neck(GO:0044326) dendritic filopodium(GO:1902737)

Showing 1 to 3 of 3 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.2	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.1	0.5	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.5	GO:0001786	phosphatidylserine binding(GO:0001786)
0.1	0.4	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.4	GO:0019239	deaminase activity(GO:0019239)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)

Showing 1 to 6 of 6 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.4	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.4	ST G ALPHA I PATHWAY	G alpha i Pathway

Showing 1 to 2 of 2 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Total log-likelihood	Term	Description
0.4	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.4	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events

Showing 1 to 3 of 3 entries

Results for zic3

Z-value: 0.43

Motif logo

Transcription factors associated with zic3

Activity-expression correlation:

Activity profile of zic3 motif

Sorted Z-values of zic3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of zic3

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: